CN104523214A - Narrow-band imaging endoscope device - Google Patents
Narrow-band imaging endoscope device Download PDFInfo
- Publication number
- CN104523214A CN104523214A CN201410820009.7A CN201410820009A CN104523214A CN 104523214 A CN104523214 A CN 104523214A CN 201410820009 A CN201410820009 A CN 201410820009A CN 104523214 A CN104523214 A CN 104523214A
- Authority
- CN
- China
- Prior art keywords
- light
- narrow
- band
- light source
- narrow band
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000003384 imaging method Methods 0.000 title claims abstract description 50
- 238000001228 spectrum Methods 0.000 claims abstract description 27
- 230000001360 synchronised effect Effects 0.000 claims abstract description 12
- 230000001678 irradiating effect Effects 0.000 claims abstract description 5
- 230000003595 spectral effect Effects 0.000 claims description 18
- 238000005286 illumination Methods 0.000 claims description 17
- 230000008878 coupling Effects 0.000 claims description 9
- 238000010168 coupling process Methods 0.000 claims description 9
- 238000005859 coupling reaction Methods 0.000 claims description 9
- 239000000835 fiber Substances 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 5
- 230000008569 process Effects 0.000 abstract description 4
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 210000001519 tissue Anatomy 0.000 description 49
- 210000004204 blood vessel Anatomy 0.000 description 9
- 229910052724 xenon Inorganic materials 0.000 description 7
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 7
- 102000001554 Hemoglobins Human genes 0.000 description 6
- 108010054147 Hemoglobins Proteins 0.000 description 6
- 239000013307 optical fiber Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 4
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 239000010410 layer Substances 0.000 description 3
- 210000004877 mucosa Anatomy 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000005265 energy consumption Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 208000017897 Carcinoma of esophagus Diseases 0.000 description 1
- 206010009944 Colon cancer Diseases 0.000 description 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 description 1
- 208000005718 Stomach Neoplasms Diseases 0.000 description 1
- 230000000712 assembly Effects 0.000 description 1
- 238000000429 assembly Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 208000029742 colonic neoplasm Diseases 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 201000005619 esophageal carcinoma Diseases 0.000 description 1
- 206010017758 gastric cancer Diseases 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 201000006866 hypopharynx cancer Diseases 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 1
- 229910052721 tungsten Inorganic materials 0.000 description 1
- 239000010937 tungsten Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00002—Operational features of endoscopes
- A61B1/00004—Operational features of endoscopes characterised by electronic signal processing
- A61B1/00009—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
- A61B1/0661—Endoscope light sources
- A61B1/0684—Endoscope light sources using light emitting diodes [LED]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00002—Operational features of endoscopes
- A61B1/00004—Operational features of endoscopes characterised by electronic signal processing
- A61B1/00009—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope
- A61B1/000094—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope extracting biological structures
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00002—Operational features of endoscopes
- A61B1/00043—Operational features of endoscopes provided with output arrangements
- A61B1/00045—Display arrangement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00064—Constructional details of the endoscope body
- A61B1/00071—Insertion part of the endoscope body
- A61B1/0008—Insertion part of the endoscope body characterised by distal tip features
- A61B1/00096—Optical elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00163—Optical arrangements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
- A61B1/0638—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
- A61B1/07—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements using light-conductive means, e.g. optical fibres
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Pathology (AREA)
- Radiology & Medical Imaging (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Signal Processing (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Endoscopes (AREA)
Abstract
The invention discloses a narrow-band imaging endoscope device which comprises a light source structure, an endoscope structure, an image processing module, a synchronous irradiating assembly and a spectrum light splitting assembly. The light source structure irradiates at least one beam of illuminating light provided with regulated wavelength frequency bands on detected tissue. The endoscope structure photographs an image of the detected tissue irradiated by the illuminating light provided with the regulated wavelength frequency bands. The image processing module processes the image photographed by the endoscope structure. The synchronous irradiating assembly irradiates the illuminating light emitted by the light source structure on the surface of the detected tissue synchronously. The spectrum light splitting assembly splits the light reflected back by the detected tissue and then inputs the light into the image processing module. The narrow-band imaging endoscope device effectively solves the problem that due to motion of the detected tissue, a narrow-band image is distorted, the structure of the endoscope device is simplified, the reliability of the endoscope device is improved, and consumed energy is reduced.
Description
Technical Field
The invention relates to an endoscope device, in particular to a narrow-band imaging endoscope device which irradiates a detected tissue with irradiation light rays of various spectrums and performs light splitting and imaging on the light rays reflected by the detected tissue simultaneously.
Background
The oxygenated hemoglobin and the deoxygenated hemoglobin in the blood have strong effect on certain specific narrow-band spectrums, and the narrow-band imaging endoscope realizes the effect of enhancing the blood vessel image in the human mucous membrane by utilizing the characteristic. The conventional electronic endoscope uses a xenon lamp or a halogen tungsten lamp and other broadband white light sources as illuminating light, and a broadband filter is added behind the white light source of the conventional narrow-band imaging endoscope to filter broadband white light, only red, green and blue narrow-band spectrums with peak wavelengths of 600nm, 540nm and 420nm are left, and the narrow-band spectrums are transmitted to the surface of a target to be observed. Since the oxygenated hemoglobin and the deoxygenated hemoglobin in the blood have strong absorption effects on the several narrow-band spectra, the blood vessels observed on the image appear as dark patterns on a bright background, improving the contrast of the blood vessel image.
Furthermore, because the penetration depths of the narrow-band spectrums with different wavelengths in the human mucosa are different, for example, the blue light band (420nm) penetrates less deeply, and can better display the blood vessels on the surface layer of the mucosa, and the green light band (540nm) penetrates deeper, and can better display the blood vessels in the middle layer. Therefore, the shot images can be decomposed and processed according to different spectrums in an image processing mode, and images with different mucosal depths can be obtained.
The narrow-band imaging endoscope has a very good effect on diagnosing and detecting some pathological changes accompanied with microvascular changes. Such as early stage hypopharynx cancer, esophageal carcinoma, early stage gastric cancer, early stage colon cancer, etc., which generally cause the increase of blood vessels in the lesion, the structure formed by capillary vessels on the surface of the mucosa will be changed. Narrow band imaging endoscopes can highlight the shape of these capillaries and thus can provide a powerful aid in the early detection of these diseases.
Patent No. CN103501683A discloses an endoscope apparatus that uses a filter wheel that rotates at high speed to filter a xenon light source. The filter disc is provided with 3 kinds of narrow-band filters with different spectral sections along the circumference, and the white light emitted by the xenon lamp can only pass through one of the narrow-band filters at the same time. Because the filter disc continuously rotates, light emitted by the xenon lamp is sequentially filtered by the 3 kinds of narrow-band filters to form a time-sequential narrow-band spectrum sequence to irradiate the surface of the detected tissue. Then shooting a reflected light image of the tissue through an endoscope imaging system, and finally obtaining a narrow-band image of the tissue through decomposition and processing of a spectral band. The majority of current narrow band imaging endoscope systems are based on such an implementation as described above. From the current application, the narrow-band imaging endoscope system using the combination of the high-power xenon lamp and the high-speed rotating filter disk has the following defects:
1. the xenon lamp has low energy utilization rate, emits broadband white light, only the part in the band-pass of the narrow-band filter is utilized after passing through the narrow-band filter, and the xenon lamp is required to have high power in order to ensure that the narrow-band image has enough brightness.
2. The image processing algorithm is complex, and in the existing narrow-band endoscope, the narrow-band light of different wave bands sequentially irradiates the surface of the measured tissue according to time sequence, so that the photographed images need to be spliced and processed by a complex algorithm.
3. The method is sensitive to the motion of a target, and because the narrow-band light of different wave bands sequentially irradiates the surface of the measured tissue according to a time sequence, if the target is displaced in the shooting process, the positions irradiated by the narrow-band light of different wave bands are changed, so that the narrow-band image is distorted.
4. The structure is complicated, the reliability is poor, the structure of the existing narrow-band endoscope comprises a plurality of mechanisms moving at high speed, the whole structure is complicated, and the reliability is poor.
Accordingly, the prior art is yet to be improved and developed.
Disclosure of Invention
The invention aims to provide a narrow-band imaging endoscope device, and aims to solve the technical problems that in the prior art, a narrow-band endoscope structure image processing algorithm is complex and has high sensitivity to target motion.
The technical scheme of the invention is as follows: a narrow band imaging endoscope apparatus includes
A light source structure for irradiating the tissue to be examined with at least one illumination light having a predetermined wavelength band;
an endoscope structure for capturing an image of a tissue under irradiation with illumination light having a predetermined wavelength band;
the image processing module is used for processing an image shot by the endoscope structure;
a display module for displaying the processed image;
wherein,
the synchronous irradiation assembly irradiates the illumination light emitted by the light source structure to the surface of the tissue to be detected simultaneously;
the device also comprises a spectrum light splitting component which splits the light reflected by the detected tissue and inputs the split light into the image processing module.
The narrow-band imaging endoscope device is characterized in that the synchronous irradiation component comprises at least one light splitting element, or the synchronous irradiation component is a light combining prism.
The narrow-band imaging endoscope device is characterized in that the spectrum light splitting component comprises at least one light splitting element, or the spectrum light splitting component is a Bayer filter.
The narrow-band imaging endoscope apparatus described above, wherein the spectroscopic element includes a dichroic mirror.
The narrow-band imaging endoscope device is characterized in that the light source structure comprises at least one LED light source.
The narrow-band imaging endoscope device is characterized in that the light source structure comprises a narrow-band light source providing a narrow-band spectrum and a broadband light source providing a broadband spectrum, wherein the narrow-band light source comprises a blue light LED providing narrow-band blue light, a green light LED providing narrow-band green light and a red light LED providing narrow-band red light; the broadband light source includes a white light LED that provides broadband white light.
The narrow-band imaging endoscope device is characterized in that the central wavelength of the blue light LED is 420nm, the central wavelength of the green light LED is 540nm, and the central wavelength of the red light LED is 600 nm.
The narrow-band imaging endoscope device is characterized in that the light source structure further comprises a movable reflector with an adjustable angle, and the movable reflector is movably adjusted to selectively irradiate the spectrum of the detected tissue.
The narrow-band imaging endoscope device is characterized in that the image processing module comprises at least one CCD image sensor.
The narrow-band imaging endoscope device is characterized in that a coupling optical fiber is connected with the endoscope structure, and the coupling optical fiber transmits the illumination light emitted by the light source structure into the endoscope structure.
The invention has the beneficial effects that: the synchronous irradiation component and the spectrum light splitting component are arranged, so that visible light emitted by the light source structure can be simultaneously irradiated into the tissue to be detected, and light reflected by the tissue to be detected can simultaneously enter the image processing module for processing, so that the problem of narrow-band image distortion caused by the movement of the tissue to be detected is effectively solved, the structure of the endoscope device is simplified, the reliability of the endoscope device is improved, and the energy consumption of the endoscope device is reduced.
Drawings
Fig. 1 is a block diagram showing the construction of a narrow band imaging endoscope apparatus according to the present invention.
Fig. 2 is a schematic diagram of a spectral splitting assembly.
Fig. 3 is a schematic diagram of a configuration in which a light combining prism and a narrow-band light source are arranged.
In the drawing, 100 light source structures, 110 blue light LEDs, 120 green light LEDs, 130 red light LEDs, 140 white light LEDs, 151 first dichroic mirrors, 152 second dichroic mirrors, 153 light-combining prisms, 160 movable reflecting mirrors, 170 condenser lenses, 200 endoscope structures, 300 image processing modules, 400 display modules, 500 coupling optical fibers, 600 spectral light splitting assemblies, 610 third dichroic mirrors, 620 fourth dichroic mirrors, 630 prism combinations, 700CCD image sensor modules, 710 first CCD image sensors, 720 second CCD image sensors, 730 third CCD image sensors are provided.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention clearer and clearer, the present invention is further described in detail below with reference to the accompanying drawings and examples.
The invention discloses a narrow-band imaging endoscope device which can irradiate a detected tissue with irradiation light rays of various spectrums at the same time, and can perform light splitting and imaging on the light rays reflected by the detected tissue at the same time. As shown in fig. 1, the narrow band imaging endoscope apparatus of the present invention includes a light source structure 100, the light source structure 100 irradiating an illumination light having a predetermined wavelength band to a tissue to be examined; an endoscope structure 200 for capturing an image of a tissue to be examined irradiated with illumination light having a predetermined wavelength band; an image processing module 300, wherein the image processing module 300 processes the image obtained by the endoscope structure 200; a display module 400, wherein the display module 400 displays the processed image. The endoscope structure 200 is inserted into the body of a human or animal, light emitted by the light source structure 100 enters the body of the human or animal through the endoscope structure 200, the detected tissue is irradiated, reflected light of the detected tissue is received by the CCD image sensor module 700 through the endoscope structure 200 to be imaged, the image is stored in the image processing module 300, and the image processing module 300 processes and synthesizes the images and displays the images in the display module 400.
As shown in fig. 1, the light source structure 100 includes a narrow-band light source providing a narrow-band spectrum including a blue LED110 providing a narrow-band blue light, a green LED120 providing a narrow-band green light, and a red LED130 providing a narrow-band red light, and a broad-band light source including a white LED140 providing a broad-band white light, and a condensing lens 170 is disposed corresponding to each light source to condense light emitted from each light source. The LED light source has the characteristics of high luminous efficiency and narrow luminous spectrum, and is very suitable for narrow-band imaging, light rays emitted by the LED light source can be basically and completely utilized, and the utilization rate of light energy is improved. In a preferred embodiment, the blue LED110 has a center wavelength of 420nm, the green LED120 has a center wavelength of 540nm, and the red LED130 has a center wavelength of 600 nm. Of course, the center wavelength of the narrow-band light source is not limited in the present invention, and the center wavelength of the narrow-band light source needs to be selected according to the special response of the examined tissue to the light. In the present invention, the narrow-band light source is preferably one whose center wavelength is located in the vicinity of the absorption peaks of oxygenated hemoglobin and deoxygenated hemoglobin in blood.
Further, in order to simultaneously irradiate the above-mentioned plurality of narrow-band light sources to the surface of the tissue to be detected, the light source structure 100 is further provided with a synchronous irradiation assembly including the first dichroic mirror 151 and the second dichroic mirror 152. The two dichroic mirrors and each narrow-band light source are arranged in parallel, the mirror surfaces on both sides of each dichroic mirror are simultaneously irradiated by two different light rays, and the light rays output (reflected or transmitted) by the dichroic mirrors simultaneously contain the two different light rays, as shown in fig. 1. The first dichroic mirror is used for transmitting light with the light wavelength lower than 450nm and reflecting light with the light wavelength higher than 450 nm; the second dichroic mirror is used for transmitting light with the light wavelength higher than 580nm and reflecting light with the light wavelength lower than 580 nm. Therefore, referring to fig. 1, the light path of the narrow-band light source includes a green LED120 and a red LED130 respectively illuminating the two side mirror surfaces of the second dichroic mirror 152, the light of the green LED120 is reflected, the light of the red LED130 is transmitted, the formed first mixed light (including the light of the green LED120 and the light of the red LED 130) and the light of the blue LED110 respectively illuminate the two side mirror surfaces of the first dichroic mirror 151, the first mixed light is reflected, the light of the blue LED110 is transmitted, the formed second mixed light (including the light of the blue LED110, the light of the green LED120 and the light of the red LED 130) is transmitted to the endoscope structure 200 through the coupling fiber 500, and the tissue to be detected is illuminated. By the facility mode, the light of each narrow-band light source is ensured to be irradiated to the same detected tissue at the same time, and the problem of distortion caused by inconsistent irradiation points of each narrow-band light source due to the movement of the detected tissue is completely solved.
Certainly, the number of dichroic mirrors is not limited in the present invention, and in practical applications, the light of multiple kinds of narrow-band light sources can be finally irradiated to the tissue to be detected through reasonable arrangement of multiple dichroic mirrors, but the number of dichroic mirrors adopted in the specific embodiment in fig. 1 is small (the number of dichroic mirrors is 1 less than the number of narrow-band light sources), and the arrangement structure is simple and is easier to implement. The number of the narrow-band light sources is not limited, in practical application, two narrow-band light sources, three narrow-band light sources (i.e., the embodiment in fig. 1) or four narrow-band light sources may be adopted, and correspondingly, the number of the dichroic mirrors also needs to be selected according to the number of the narrow-band light sources.
In practical applications, besides the dichroic mirror, other light splitting optical elements or light combining elements may be used to simultaneously irradiate the tissues to be detected with the lights from multiple kinds of narrow-band light sources, for example, in another preferred embodiment, as shown in fig. 3, the light splitting and light combining elements may be used to realize the light splitting and light combining by using one light combining prism 153, and the three narrow-band light sources are respectively disposed on three sides of the light combining prism 153 to simultaneously irradiate the light combining prism 153, and then are combined by the light combining prism 153 to output the light including three narrow-band spectrums.
In practical applications, as shown in fig. 1, a movable mirror 160 may be provided to select a narrow-band light source or a wide-band white light. The movable mirror 160 can rotate at 45 °, and when it rotates to the position of the dotted line in fig. 1, the light of the narrow-band light source can be blocked, and the broadband white light can be reflected.
In order to realize the purpose that the light reflected by the detected tissue is split and then simultaneously input into the image processing module for processing, the narrow-band imaging endoscope device further comprises a spectral splitting assembly 600. As shown in fig. 2, spectral splitting assembly 600 includes a third dichroic mirror 610, a fourth dichroic mirror 620, and a prism combination 630, where third dichroic mirror 610 functions to transmit light with a wavelength of below 580nm and reflect light with a wavelength of above 580nm, and fourth dichroic mirror 620 functions to transmit light with a wavelength of below 450nm and reflect light with a wavelength of above 450 nm. In this embodiment, three CCD image sensors are provided, namely, a first CCD image sensor 710, a second CCD image sensor 720 and a third CCD image sensor 730 (the number of CCD image sensors corresponds to the number of narrow-band spectra that need to be received). The working principle of the spectral splitting assembly 600 is as follows: the mixed light reflected by the tissue to be detected, which includes narrow-band red light (center wavelength is 600nm), narrow-band green light (center wavelength is 540nm), and narrow-band blue light (center wavelength is 420nm), enters the spectral splitting assembly 600, passes through the third dichroic mirror 610, the narrow-band red light is reflected, is reflected by the prism combination 630, enters the first CCD image sensor 710 for imaging, the narrow-band green light and the narrow-band blue light are transmitted from the third dichroic mirror 610, passes through the fourth dichroic mirror 620, the narrow-band green light is reflected by the fourth dichroic mirror 620, is reflected by the prism combination 630, enters the second CCD image sensor 720 for imaging, and the narrow-band blue light is transmitted from the fourth dichroic mirror 620, and enters the third CCD image sensor 730 for imaging (the specific optical path is shown in fig. 2). Through the arrangement mode, the light reflected by the detected tissue is subjected to spectrum splitting and then enters the corresponding CCD image sensors for imaging and storage, so that the accuracy of the device is improved, the complexity of an image processing module algorithm is greatly reduced, the imaging efficiency is improved, and the distortion and the error rate are reduced.
Of course, in practical applications, other combinations of optical elements and image sensors may be adopted instead of the combination structure of the dichroic mirror, the prism combination and the three CCD image sensors in the spectral splitting assembly 600, for example, in another preferred embodiment, a combination of the bayer filter and one CCD image sensor may be adopted to realize simultaneous imaging of three kinds of narrow-band light.
The narrow-band imaging endoscope device in fig. 1 specifically works as follows: the doctor selects broadband white light or narrow-band illumination light according to the illness state of the patient; if the doctor selects the narrow-band illumination light, the control circuit sends a control signal to the driving circuit, so that the movable reflector 160 moves to the position A, the blue LED110, the green LED120 and the red LED130 emit light simultaneously, and the white LED140 stops emitting light. After passing through the synchronous irradiation component, each narrow-band light forms mixed light to be coupled into the coupling optical fiber 500, and is irradiated onto the measured tissue through the coupling optical fiber 500 and the endoscope structure 200. The endoscope structure 200 collects light reflected on the tissue under test and transmits it to the spectral splitting assembly 600. The spectral splitting assembly 600 splits the narrow-band light reflected from the tissue to be examined according to different spectral bands, and transmits the corresponding narrow-band reflected light to the corresponding CCD image sensor. The narrow-band blue light reflected by the surface of the tissue to be detected enters the third CCD image sensor 730 after passing through the spectral splitting assembly 600, and the depth of the narrow-band blue light entering the tissue to be detected is shallow, so that an image formed in the third CCD image sensor 730 is a blood vessel image of the surface of the tissue to be detected; narrow-band green light reflected by the surface of the detected tissue enters the second CCD image sensor 720 after passing through the spectral light splitting assembly 600, and the depth of the narrow-band green light entering the detected tissue is deep, so an image formed in the second CCD image sensor 720 is a blood vessel image of the middle layer of the detected tissue; narrow-band red light reflected by the surface of the tissue to be detected enters the first CCD image sensor 710 after passing through the spectral light splitting assembly 600, and the depth of the narrow-band red light entering the tissue to be detected is the deepest, so that an image formed in the first CCD image sensor 710 is a blood vessel image of the lower layer of the tissue to be detected. The image processing module 300 synthesizes the three sets of images to obtain tissue images of the tissue to be measured at different depths under the narrow-band illumination light, and the tissue images are displayed by the display module 400. If the doctor selects the broadband white light illumination light, the control circuit sends a control signal to the driving circuit, so that the movable reflector 160 moves to the position B, the blue light LED110, the green light LED120 and the red light LED130 pause to emit light, the white light LED140 emits light, the broadband white light illumination light is coupled to enter the coupling optical fiber 500, and at the moment, the narrow-band imaging endoscope device can shoot the tissue picture which is the same as that of the traditional white light endoscope.
The invention utilizes three narrow-band LED light sources to simultaneously irradiate the tissue to be detected in combination with the synchronous irradiation component, uses the spectral light-splitting device to respectively enter the narrow-band light reflected on the tissue to be detected into the three CCD image sensors for simultaneous imaging, and overcomes the defect that the different narrow-band light of the traditional narrow-band endoscope is sensitive to target motion due to time sequence imaging. The image processing module of the invention has the advantages of simple algorithm, high efficiency, high image synthesis precision and small distortion. The device has simple structure, no high-speed moving part and high reliability. The LED light source adopted by the invention has low energy consumption and high energy utilization efficiency.
It is to be understood that the invention is not limited to the examples described above, but that modifications and variations may be effected thereto by those of ordinary skill in the art in light of the foregoing description, and that all such modifications and variations are intended to be within the scope of the invention as defined by the appended claims.
Claims (10)
1. A narrow band imaging endoscope apparatus includes
A light source structure for irradiating the tissue to be examined with at least one illumination light having a predetermined wavelength band;
an endoscope structure for capturing an image of a tissue under irradiation with illumination light having a predetermined wavelength band;
the image processing module is used for processing an image shot by the endoscope structure;
it is characterized in that the preparation method is characterized in that,
the synchronous irradiation assembly irradiates the illumination light emitted by the light source structure to the surface of the tissue to be detected simultaneously;
the device also comprises a spectrum light splitting component which splits the light reflected by the detected tissue and inputs the split light into the image processing module.
2. The narrow band imaging endoscopic device of claim 1 wherein the synchronized illumination assembly comprises at least one beam splitting element or the synchronized illumination assembly is a beam combining prism.
3. The narrowband imaging endoscopic device of claim 1, wherein the spectral splitting assembly comprises at least one splitting element, or wherein the spectral splitting assembly is a bayer filter.
4. The narrowband imaging endoscopic device of claim 2 or 3, wherein the light splitting element comprises a dichroic mirror.
5. The narrow band imaging endoscopic device of claim 1 wherein the light source structure comprises at least one LED light source.
6. The narrow band imaging endoscopic device of claim 5 wherein the light source arrangement comprises a narrow band light source providing a narrow band spectrum of light and a broad band light source providing a broad band spectrum of light, the narrow band light source comprising a blue LED providing a narrow band blue light, a green LED providing a narrow band green light, and a red LED providing a narrow band red light; the broadband light source includes a white light LED that provides broadband white light.
7. The narrow band imaging endoscope apparatus of claim 6, wherein the blue LEDs have a center wavelength of 420nm, the green LEDs have a center wavelength of 540nm, and the red LEDs have a center wavelength of 600 nm.
8. The narrow band imaging endoscopic device of claim 6 wherein the light source configuration further comprises an angularly adjustable movable mirror that actively adjusts the spectrum selected to illuminate the tissue being examined.
9. The narrow band imaging endoscopic device of claim 1 wherein the image processing module comprises at least one CCD image sensor.
10. The narrow band imaging endoscopic device of claim 1 wherein a coupling fiber is attached to the endoscopic structure, the coupling fiber transmitting illumination light from the light source structure into the endoscopic structure.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410820009.7A CN104523214A (en) | 2014-12-19 | 2014-12-19 | Narrow-band imaging endoscope device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410820009.7A CN104523214A (en) | 2014-12-19 | 2014-12-19 | Narrow-band imaging endoscope device |
Publications (1)
Publication Number | Publication Date |
---|---|
CN104523214A true CN104523214A (en) | 2015-04-22 |
Family
ID=52838986
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201410820009.7A Pending CN104523214A (en) | 2014-12-19 | 2014-12-19 | Narrow-band imaging endoscope device |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104523214A (en) |
Cited By (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106308751A (en) * | 2016-08-23 | 2017-01-11 | 江苏鹰利视医疗器械有限公司 | Device for achieving narrow-band or broad-band spectrum combined lighting and method thereof |
CN107149461A (en) * | 2017-04-26 | 2017-09-12 | 上海成运医疗器械股份有限公司 | The LED/light source and means of illumination of illumination are dyed for Medical endoscope spectrum |
CN107456202A (en) * | 2017-10-01 | 2017-12-12 | 凝辉(天津)科技有限责任公司 | A kind of nonlinear optics flexible endoscope imaging device |
CN107635452A (en) * | 2015-06-02 | 2018-01-26 | 奥林巴斯株式会社 | Special optical endoscope device |
CN107837064A (en) * | 2017-11-02 | 2018-03-27 | 北京华信佳音医疗科技发展有限责任公司 | A kind of endoscope arrowband cold light source device |
CN108937825A (en) * | 2018-04-20 | 2018-12-07 | 南京图格医疗科技有限公司 | A kind of multispectral light source fusion of imaging system |
CN108992023A (en) * | 2018-08-15 | 2018-12-14 | 重庆金山医疗器械有限公司 | Illumination for endoscope system |
CN109222858A (en) * | 2018-11-19 | 2019-01-18 | 苏州新光维医疗科技有限公司 | Endoscope structure with various light sources |
CN109381153A (en) * | 2018-09-28 | 2019-02-26 | 北京凡星光电医疗设备股份有限公司 | A kind of endoscope image pick-up device |
CN109452922A (en) * | 2018-12-17 | 2019-03-12 | 深圳开立生物医疗科技股份有限公司 | A kind of endoscope and its light supply apparatus |
CN109620110A (en) * | 2019-01-15 | 2019-04-16 | 深圳英美达医疗技术有限公司 | A kind of lighting device and endoscopic system |
CN110731748A (en) * | 2019-11-18 | 2020-01-31 | 深圳开立生物医疗科技股份有限公司 | electronic endoscope |
CN110881941A (en) * | 2019-12-24 | 2020-03-17 | 广东欧谱曼迪科技有限公司 | Electronic soft lens with fluorescence and narrow-band spectral imaging technology and implementation method thereof |
WO2020103698A1 (en) * | 2018-11-19 | 2020-05-28 | 苏州新光维医疗科技有限公司 | Endoscope structure having different light sources |
CN111308691A (en) * | 2020-04-16 | 2020-06-19 | 厦门行者科创科技有限公司 | Narrow-band light endoscopic imaging system |
CN111557632A (en) * | 2020-06-12 | 2020-08-21 | 深圳开立生物医疗科技股份有限公司 | Endoscope light source and endoscope system |
CN112904549A (en) * | 2021-01-29 | 2021-06-04 | 武汉联影智融医疗科技有限公司 | Multi-color mixed light illumination method and system |
CN113616138A (en) * | 2021-08-03 | 2021-11-09 | 北京双翼麒电子有限公司 | Multispectral endoscope image processing system |
EP3878344A4 (en) * | 2018-11-07 | 2021-12-08 | Sony Group Corporation | Image acquisition system and image acquisition method |
CN114041737A (en) * | 2021-11-16 | 2022-02-15 | 四川大学华西医院 | Imaging device applied to endoscope |
CN114287871A (en) * | 2022-03-09 | 2022-04-08 | 杭州康基医疗器械有限公司 | Medical endoscope fluorescence cold light source camera system with high-efficient heat radiation structure |
CN114391792A (en) * | 2021-09-13 | 2022-04-26 | 南京诺源医疗器械有限公司 | Tumor prediction method and device based on narrow-band imaging and imaging endoscope |
CN114468950A (en) * | 2021-12-30 | 2022-05-13 | 浙江大学 | Mixed illumination autofluorescence laparoscope |
CN114468949A (en) * | 2021-12-30 | 2022-05-13 | 浙江大学 | Multispectral endoscope image processing method and system |
CN115736791A (en) * | 2022-11-28 | 2023-03-07 | 北京大学 | Endoscopic imaging device and method |
WO2023116727A1 (en) * | 2021-12-20 | 2023-06-29 | 上海安翰医疗技术有限公司 | Imaging apparatus and capsule endoscope |
WO2024037590A1 (en) * | 2022-08-17 | 2024-02-22 | 常州联影智融医疗科技有限公司 | Light source apparatus and endoscopic system |
Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007068699A (en) * | 2005-09-06 | 2007-03-22 | Media Technology:Kk | Light source unit |
JP2007175210A (en) * | 2005-12-27 | 2007-07-12 | Pentax Corp | Self-fluorescence observation apparatus |
US20100280322A1 (en) * | 2008-06-04 | 2010-11-04 | Fujifilm Corporation | Illumination device for use in endoscope |
CN102188226A (en) * | 2010-03-19 | 2011-09-21 | 富士胶片株式会社 | An electronic endoscope system, an electronic endoscope processor, and a method of acquiring blood vessel information |
CN102274000A (en) * | 2011-05-16 | 2011-12-14 | 易定容 | Narrow-band multispectral fluorescent vagina check device |
US20120157774A1 (en) * | 2010-12-15 | 2012-06-21 | Toshihiko Kaku | Endoscopy system |
CN103190878A (en) * | 2013-03-22 | 2013-07-10 | 浙江大学 | Multifunctional medical LED (Light Emitting Diode) lighting system |
CN103431833A (en) * | 2013-05-24 | 2013-12-11 | 中国科学院苏州生物医学工程技术研究所 | Medical multiband narrow band imaging system |
CN103732117A (en) * | 2011-12-07 | 2014-04-16 | 奥林巴斯医疗株式会社 | Endoscope device |
CN103796571A (en) * | 2012-03-29 | 2014-05-14 | 奥林巴斯医疗株式会社 | Endoscope system |
CN103987309A (en) * | 2012-05-01 | 2014-08-13 | 奥林巴斯医疗株式会社 | Endoscope device |
WO2014123000A1 (en) * | 2013-02-07 | 2014-08-14 | オリンパス株式会社 | Light source device |
CN204379226U (en) * | 2014-12-19 | 2015-06-10 | 佛山市南海区欧谱曼迪科技有限责任公司 | A kind of Narrow-Band Imaging endoscope apparatus |
-
2014
- 2014-12-19 CN CN201410820009.7A patent/CN104523214A/en active Pending
Patent Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007068699A (en) * | 2005-09-06 | 2007-03-22 | Media Technology:Kk | Light source unit |
JP2007175210A (en) * | 2005-12-27 | 2007-07-12 | Pentax Corp | Self-fluorescence observation apparatus |
US20100280322A1 (en) * | 2008-06-04 | 2010-11-04 | Fujifilm Corporation | Illumination device for use in endoscope |
CN102188226A (en) * | 2010-03-19 | 2011-09-21 | 富士胶片株式会社 | An electronic endoscope system, an electronic endoscope processor, and a method of acquiring blood vessel information |
US20120157774A1 (en) * | 2010-12-15 | 2012-06-21 | Toshihiko Kaku | Endoscopy system |
CN102274000A (en) * | 2011-05-16 | 2011-12-14 | 易定容 | Narrow-band multispectral fluorescent vagina check device |
CN103732117A (en) * | 2011-12-07 | 2014-04-16 | 奥林巴斯医疗株式会社 | Endoscope device |
CN103796571A (en) * | 2012-03-29 | 2014-05-14 | 奥林巴斯医疗株式会社 | Endoscope system |
CN103987309A (en) * | 2012-05-01 | 2014-08-13 | 奥林巴斯医疗株式会社 | Endoscope device |
WO2014123000A1 (en) * | 2013-02-07 | 2014-08-14 | オリンパス株式会社 | Light source device |
CN103190878A (en) * | 2013-03-22 | 2013-07-10 | 浙江大学 | Multifunctional medical LED (Light Emitting Diode) lighting system |
CN103431833A (en) * | 2013-05-24 | 2013-12-11 | 中国科学院苏州生物医学工程技术研究所 | Medical multiband narrow band imaging system |
CN204379226U (en) * | 2014-12-19 | 2015-06-10 | 佛山市南海区欧谱曼迪科技有限责任公司 | A kind of Narrow-Band Imaging endoscope apparatus |
Cited By (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107635452B (en) * | 2015-06-02 | 2019-09-13 | 奥林巴斯株式会社 | Special optical endoscope device |
CN107635452A (en) * | 2015-06-02 | 2018-01-26 | 奥林巴斯株式会社 | Special optical endoscope device |
CN106308751A (en) * | 2016-08-23 | 2017-01-11 | 江苏鹰利视医疗器械有限公司 | Device for achieving narrow-band or broad-band spectrum combined lighting and method thereof |
CN107149461A (en) * | 2017-04-26 | 2017-09-12 | 上海成运医疗器械股份有限公司 | The LED/light source and means of illumination of illumination are dyed for Medical endoscope spectrum |
CN107456202A (en) * | 2017-10-01 | 2017-12-12 | 凝辉(天津)科技有限责任公司 | A kind of nonlinear optics flexible endoscope imaging device |
CN107837064A (en) * | 2017-11-02 | 2018-03-27 | 北京华信佳音医疗科技发展有限责任公司 | A kind of endoscope arrowband cold light source device |
CN108937825A (en) * | 2018-04-20 | 2018-12-07 | 南京图格医疗科技有限公司 | A kind of multispectral light source fusion of imaging system |
CN108992023A (en) * | 2018-08-15 | 2018-12-14 | 重庆金山医疗器械有限公司 | Illumination for endoscope system |
CN109381153A (en) * | 2018-09-28 | 2019-02-26 | 北京凡星光电医疗设备股份有限公司 | A kind of endoscope image pick-up device |
EP3878344A4 (en) * | 2018-11-07 | 2021-12-08 | Sony Group Corporation | Image acquisition system and image acquisition method |
US11509870B2 (en) | 2018-11-07 | 2022-11-22 | Sony Group Corporation | Image acquisition system and image acquisition method |
WO2020103698A1 (en) * | 2018-11-19 | 2020-05-28 | 苏州新光维医疗科技有限公司 | Endoscope structure having different light sources |
CN109222858A (en) * | 2018-11-19 | 2019-01-18 | 苏州新光维医疗科技有限公司 | Endoscope structure with various light sources |
CN109452922A (en) * | 2018-12-17 | 2019-03-12 | 深圳开立生物医疗科技股份有限公司 | A kind of endoscope and its light supply apparatus |
CN109620110A (en) * | 2019-01-15 | 2019-04-16 | 深圳英美达医疗技术有限公司 | A kind of lighting device and endoscopic system |
CN110731748A (en) * | 2019-11-18 | 2020-01-31 | 深圳开立生物医疗科技股份有限公司 | electronic endoscope |
CN110881941A (en) * | 2019-12-24 | 2020-03-17 | 广东欧谱曼迪科技有限公司 | Electronic soft lens with fluorescence and narrow-band spectral imaging technology and implementation method thereof |
CN111308691A (en) * | 2020-04-16 | 2020-06-19 | 厦门行者科创科技有限公司 | Narrow-band light endoscopic imaging system |
CN111557632A (en) * | 2020-06-12 | 2020-08-21 | 深圳开立生物医疗科技股份有限公司 | Endoscope light source and endoscope system |
CN112904549A (en) * | 2021-01-29 | 2021-06-04 | 武汉联影智融医疗科技有限公司 | Multi-color mixed light illumination method and system |
CN113616138B (en) * | 2021-08-03 | 2024-05-03 | 北京双翼麒电子有限公司 | Multispectral endoscope image processing system |
CN113616138A (en) * | 2021-08-03 | 2021-11-09 | 北京双翼麒电子有限公司 | Multispectral endoscope image processing system |
CN114391792A (en) * | 2021-09-13 | 2022-04-26 | 南京诺源医疗器械有限公司 | Tumor prediction method and device based on narrow-band imaging and imaging endoscope |
CN114391792B (en) * | 2021-09-13 | 2023-02-24 | 南京诺源医疗器械有限公司 | Tumor prediction method and device based on narrow-band imaging and imaging endoscope |
CN114041737A (en) * | 2021-11-16 | 2022-02-15 | 四川大学华西医院 | Imaging device applied to endoscope |
WO2023116727A1 (en) * | 2021-12-20 | 2023-06-29 | 上海安翰医疗技术有限公司 | Imaging apparatus and capsule endoscope |
CN114468950A (en) * | 2021-12-30 | 2022-05-13 | 浙江大学 | Mixed illumination autofluorescence laparoscope |
CN114468949A (en) * | 2021-12-30 | 2022-05-13 | 浙江大学 | Multispectral endoscope image processing method and system |
CN114287871B (en) * | 2022-03-09 | 2022-07-29 | 杭州康基医疗器械有限公司 | Medical endoscope fluorescence cold light source camera system with high-efficient heat radiation structure |
CN114287871A (en) * | 2022-03-09 | 2022-04-08 | 杭州康基医疗器械有限公司 | Medical endoscope fluorescence cold light source camera system with high-efficient heat radiation structure |
WO2024037590A1 (en) * | 2022-08-17 | 2024-02-22 | 常州联影智融医疗科技有限公司 | Light source apparatus and endoscopic system |
CN115736791A (en) * | 2022-11-28 | 2023-03-07 | 北京大学 | Endoscopic imaging device and method |
CN115736791B (en) * | 2022-11-28 | 2024-05-07 | 北京大学 | Endoscopic imaging device and method |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN104523214A (en) | Narrow-band imaging endoscope device | |
CN204379226U (en) | A kind of Narrow-Band Imaging endoscope apparatus | |
US10798310B2 (en) | Hyperspectral imager coupled with indicator molecule tracking | |
KR102506587B1 (en) | Camera having light emitting device, method for imaging skin and method for detecting skin conditions using the same | |
US9526427B2 (en) | Compact light sensors with symmetrical lighting | |
US11206987B2 (en) | Method and apparatus for concurrent imaging at visible and infrared wavelengths | |
US9433350B2 (en) | Imaging system and method for the fluorescence-optical visualization of an object | |
JP6204314B2 (en) | Electronic endoscope system | |
US20130245411A1 (en) | Endoscope system, processor device thereof, and exposure control method | |
CN108697307A (en) | computing system | |
US9918613B2 (en) | Endoscope system and operating method thereof | |
US9345392B2 (en) | Endoscope system and method for imaging exposure control | |
JP5222934B2 (en) | Endoscope system, processor device for endoscope system, and method for operating endoscope system | |
US20130338438A1 (en) | Fluorescence endoscope apparatus | |
US9113814B2 (en) | Endoscope apparatus capable of providing narrow band imaging and image processing method of the endoscope apparatus | |
JP2007029453A (en) | Lighting device and observation device | |
JP2006181387A (en) | Endoscope apparatus | |
WO2023116722A1 (en) | Imaging apparatus and method, and capsule endoscope | |
RU2290855C1 (en) | Method and device for carrying out fluorescent endoscopy | |
CN110731748B (en) | Electronic endoscope | |
CN211213049U (en) | Electronic endoscope | |
CN109549614B (en) | Endoscope system | |
CN216984858U (en) | Illumination module, endoscope imaging system and endoscope | |
JP5483522B2 (en) | Image acquisition device | |
JP7426248B2 (en) | Medical control device and medical observation system |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150422 |
|
RJ01 | Rejection of invention patent application after publication |