CN104522729A - 一种海参营养咀嚼片 - Google Patents
一种海参营养咀嚼片 Download PDFInfo
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- CN104522729A CN104522729A CN201410716747.7A CN201410716747A CN104522729A CN 104522729 A CN104522729 A CN 104522729A CN 201410716747 A CN201410716747 A CN 201410716747A CN 104522729 A CN104522729 A CN 104522729A
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- sea cucumber
- root
- chitin
- trepang
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Classifications
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- A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
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Abstract
本发明提供了一种海参营养咀嚼片,其中,包括按照重量份数配置的如下活性组分:中药料:酸枣仁30-50份,没药20-40份,红花20-40份,竹茹20-40份,橘红10-30份,威灵仙10-30份,地耳草10-30份,猪苓10-30份,丝瓜络10-30份,生地黄10-30份,红藤10-30份,金银花10-30份,黄芩10-30份,石膏10-30份,基础料:海参300-500份;附加料:甲壳素3-6份、淀粉10-20份、糊精5-10份、甘露醇3-6份,甜味剂1-4份,微晶纤维素1-4份。本发明配比简单,组方搭配合理,促进免疫调解、增加伤口愈合速度。
Description
技术领域:
本发明涉及海参深加工技术领域,尤其涉及一种海参营养咀嚼片。
背景技术:
海参含胆固醇极低,为一种典型的高蛋白、低脂肪、低胆固醇食物。加上其肉质细嫩,易于消化,所以,非常适宜于老年人、儿童以及体质虚弱的人食用。海参因含胆固醇极低,为一种典型的高蛋白、低脂肪、低胆固醇的食物。又因肉质细嫩,易于消化,所以非常适合老年人与儿童,以及体质虚弱者食用。海参中的牛磺酸、尼克酸等,具有调节神经系统、快速消除疲劳,预防皮肤老化的功效,另外海参中含有的牛磺酸、赖氨酸、蛋氨酸等在植物性食品中几乎没有,刺参中含有的硫酸软骨素和刺参粘多糖,通过药理实验证明,对人体的生长发育、抗炎成骨和预防组织老化,促进伤口愈合抑制数种癌细胞都有特殊功效。延续衰老,消除疲劳,提高免疫力,增强抵抗疾病的能力 海参富含蛋白质、矿物质、维生素等50多种天然珍贵活性物质,其中酸性粘多糖和软骨素可明显降低心脏组织中脂褐素和皮肤脯氨酸的数量,起到延缓衰老的作用。海参体内所含的18种氨基酸能够增强组织的代谢功能,增强机体细胞活力,适宜于生长发育中的青少年。海参能调节人体水份平衡,适宜于孕期腿脚浮肿的女士。海参能消除疲劳,提高人体免疫力,增强人体抵抗疾病的能力,因此非常适合经常处于疲劳状态的中年女士与男士,易感冒、体质虚弱的老年人和儿童等亚健康人群。
海参的其他功用,如消除肿瘤、抗癌护心脏:在海参的体壁、内脏和腺体等组织中含有大量的海参毒素,又叫海参皂甙。海参毒素是一种抗毒剂,对人体安全无毒,但能抑制肿瘤细胞的生长与转移,有效防癌、抗癌,临床上已广泛应用于肝癌、肺癌、胃癌、鼻咽癌、骨癌、淋巴癌、卵巢癌、子宫癌、乳腺癌、脑癌白血病及手术后患者的治疗。改善骨质疏松经常食用海参可以预防儿童的佝偻病、成人的骨质疏松症和骨质增生症。金至尊海参中丰富的钙、磷、锰、铜、锗、硅等元素对预防婴儿佝偻病,成人的骨质疏松症以及对骨骼异常、畸形,牙质及釉质发育不良都有特殊作用。促进生长发育 食用海参有助于促进生长发育。海参中丰富的精氨酸、赖氨酸、牛磺酸、钙、磷、碘、铁、锌,是人体发育成长的重要物质,它们直接参与人体本身的生长发育、免疫调解、伤口愈合、生殖发育等生理活动,在人体能量储备和运转中起着重要作用,因此,作为术后的营养品,海参可以大大加快伤口的愈合速度。
在日常生活和医疗中,创伤是在所难免的,如外伤、手术等都可引起一定的创伤。由于创伤愈合的状况与病情的发展密切相关,故创伤愈合成为现今医学研究中重要的热点之一。近年来,中草药逐渐受到人们的青睐,中医药事业正在茁壮发展,中草药促创伤愈合的研究也不断涌现。现就对中草药促进创伤愈合的作用及机制综述如下。中医对创伤愈合的认识 《正体类要》注曰:“肢体损于外,则气血伤于内,营卫有所不贯,脏腑由之不和。”指出机体创伤后气血失养、营卫失和导致气血凝滞、经络阻塞、脏腑功能失调。创面的气血盛衰、营卫强弱对创面的愈合至关重要,故活血化瘀、行气通络是治疗创伤的关键。中医学认为,创伤是由外因导致的,“伤”是在皮肤表层、程度较浅,而“创”指金属利刃导致的损害,程度深达肌肉。无论何种外伤,都会伤及血络、脉管,出现出血、瘀血或血肿,止血、消肿、活血是治疗外伤的必不可少的步骤。中医药促进创面肉芽组织生长主要集中在祛腐生肌、祛瘀生肌和补益生肌等方面。
海参对于促进伤口愈合具有显著效果,所以,通常作为术后或创后的营养补品。目前海参的服用方法,仍然以食补为主,食补导致人体吸收率不足,而且,一些烹饪的禁忌也常常导致海参营养成分损失,如,海参不能用醋做调味品。因此,市面上出现了一些海参深加工产品,如口服液,片剂,胶囊,蜜炼丸剂等等,深加工的过程中,往往加入中成药以提高产品的吸收率或增加其他附属功能,但是,有些配方不合理,例如,海参不能与甘草配伍等等。因此,本发明旨在提供一种配比简单,组方搭配合理,促进免疫调解、增加伤口愈合速度的一种海参营养咀嚼片。
发明内容:
本发明的目的在于克服现有技术中存在的缺点,提供一种配比简单,组方搭配合理,促进免疫调解、增加伤口愈合速度一种海参营养咀嚼片。
为了实现上述目的,本发明提供了一种海参营养咀嚼片,其中,包括按照重量份数配置的如下活性组分:
中药料:酸枣仁30-50份,没药20-40份,红花20-40份,竹茹20-40份,橘红10-30份,威灵仙10-30份,地耳草10-30份,猪苓10-30份,丝瓜络10-30份,生地黄10-30份,红藤10-30份,金银花10-30份,黄芩10-30份,石膏10-30份,
基础料:海参300-500份;
附加料:甲壳素3-6份、淀粉10-20份、糊精5-10份、甘露醇3-6份,甜味剂1-4份,微晶纤维素1-4份。
或者,包括按照重量份数配置的如下活性组分:
中药料:酸枣仁30-40份,没药20-30份,红花20-30份,竹茹20-30份,橘红10-20份,威灵仙10-20份,地耳草10-20份,猪苓10-20份,丝瓜络10-20份,生地黄10-20份,红藤10-20份,金银花10-20份,黄芩10-20份,石膏10-20份,
基础料:海参300-400份;
附加料:甲壳素3-5份,淀粉10-15份、糊精5-8份、甘露醇3-5份,甜味剂1-3份,微晶纤维素1-3份。
或者,包括按照重量份数配置的如下活性组分:
中药料:酸枣仁40-50份,没药30-40份,红花30-40份,竹茹30-40份,橘红20-30份,威灵仙20-30份,地耳草20-30份,猪苓20-30份,丝瓜络20-30份,生地黄20-30份,红藤20-30份,金银花20-30份,黄芩20-30份,石膏20-30份,
基础料:海参400-500份;
附加料:甲壳素4-6份,淀粉15-20份、糊精8-10份、甘露醇4-6份,甜味剂2-4份,微晶纤维素2-4份。
或者,包括按照重量份数配置的如下活性组分:
中药料:中药料:酸枣仁35-45份,没药25-35份,红花25-35份,竹茹25-35份,橘红15-25份,威灵仙15-25份,地耳草15-25份,猪苓15-25份,丝瓜络15-25份,生地黄15-25份,红藤15-25份,金银花15-25份,黄芩15-25份,石膏15-25份,
基础料:海参350-450份;
附加料:甲壳素4-5份,淀粉12-18份、糊精6-9份、甘露醇2-5份,甜味剂2-3份,微晶纤维素2-3份。
为更好的实现本发明的目的,本发明又公开了海参营养咀嚼片的制备方法,其中,包括如下步骤:
A、清洗的步骤:将酸枣仁,没药,红花,竹茹,橘红,威灵仙,地耳草,猪苓,丝瓜络,生地黄,红藤,金银花,黄芩,石膏,使用滚筒式洗药机进行清洗,清洗时间控制在3-5分钟,避免药效流失;
B、润药的步骤:将步骤A清洗干净的中药组分,使用注水式润药机进行润药操作,润药使失水的植物细胞吸水膨胀,为提取工序创造条件;
C、上述组份加重量10倍量乙醇,加热回流提取3次,每次2小时,将3次提取液合并,减压回收乙醇,并浓缩至药液浓度为0.5g生药/mL,抽滤后,滤液的相对密度为20℃时1.08;所述滤液流经体积为10L的大孔吸附树脂柱,之后用10倍树脂柱体积的去离子水或蒸馏水洗脱,再用5倍树脂柱体积的95%乙醇洗脱,收集乙醇洗脱液,去除乙醇溶剂,得到中药药粉,再经80目筛子过筛后,经紫外线杀菌后备用;
D、海参深加工的步骤:鲜活海参,沿腹部从头至尾全剖开,去除内脏,将杂质清洗干净;接着进行冷冻干燥,冷冻温度为-20~-25℃,真空度为5-15Pa,快速冷冻2-3h,将冷冻干燥后的海参放入粉碎机,粉碎10-30min,过60 目筛,得到粗海参粉;将海参粗粉通过气流粉碎机进行超微粉碎,时间2-3h,得到超微海参粉;然后将超微海参粉通过高速剪切超细粉碎机进行纳米化粉碎,粉碎时间为3-5h;
向容器中加入纯净水,使纳米化粉碎后的海参粉与水以1 :5-10 质量比溶解,得到海参浆,称取海参重量0.3-0.4% 的复合蛋白酶,复合蛋白酶为胃蛋白酶的菠萝酶胃的混合物,蛋白酶:菠萝酶的质量比=2:1,使用纯净水将复合蛋白酶溶化后,连同海参浆一起放入酶解罐中,在强度为500-1000w 的微波环境中静置1-2min,进行微波酶解作业,酶解完成后,将酶解液迅速升温度至90℃灭酶10-30min ;完成酶的灭活后,对酶解罐停止加热,将酶解液迅速冷却至常温;酶解罐用纯净水冲洗,冲洗液放入酶解液中;将降温后的酶解液先用普通离心机离心20min,过滤;取滤液,低温超高速离心20min,过滤,得滤液;将滤液通过纳滤以除去盐分;剩余物过100 目筛,得到海参提取液;
E、制备胶囊的步骤:将步骤C所得中药药粉加入到步骤D所得的海参提取液中,中药药粉:海参提取液的重量比为1-1.2:1-1.5;混合均匀后,加入附加料,得到的混合物呈糊状,压片成型,干燥得咀嚼片。
附加料中的成分如下:
甲壳素(即甲壳质)的医理作用如下:1、外伤止血,血小板与血液中的甲壳质结合,能提高创伤组织的粘附力,快速使局部血管收缩,降低出血数量。2、提高伤口愈合速度,新的组织细胞的增殖、形成急需多量的基础物质,透明质酸是重要的材料。甲壳质能增加组织中透明质酸的数量,促进细胞膜的形成。并在活化细胞过程中,产生大量胶原纤维,迅速形成密质皮肤,不会留下疤痕。3、甲壳质能够防治创伤面感染,甲壳质外用在创伤局部可抑制细菌生长,国内外文献报告甲壳质敷在体外伤口能够抑制革兰氏阳性菌和白念珠菌生长,5 mg/ml抑菌率达75~100%;可增加创伤局部吞噬细胞的数量和活性;及时消除坏死组织,促进肉芽组织的形成。构成创伤口愈合的这三大要素,相辅相成综合起作用。4、甲壳质在骨外科上的应用,甲壳质做为骨缺损部填充物,由于帮助血小板粘附加速凝集显示良好的止血作用,在甲壳质的周围聚集多量的吞噬细胞、巨噬细胞,抑制局部病原菌的侵袭具有明显的加速骨修复的作用。
淀粉 :比较常用的是玉米淀粉,它的性质非常稳定,与大多数药物不起作用,价格也比较便宜,吸湿性小、外观色泽好,在实际生产中,常与可压性较好的糖粉、糊精混合使用,这是因为淀粉的可压性较差,若单独使用,会使压出的药片过于松散。
糊精:糊精是淀粉水解中间产物的总称,其化学式为(C6H10O5)n·XH2O,其水溶物约为80%,在冷水中溶解较慢,较易溶于热水,不溶于乙醇。习惯上亦称其为为高糊(高粘度糊精),即具有较强的粘结性。
微晶纤维素:微晶纤维素(Microcrystalline cellulose, MCC)是纤维素部分水解而制得的聚合度较小的结晶性纤维素,具有良好的可压性,有较强的结合力,压成的片剂有较大有硬度,可作为粉末直接压片的“干粘合剂”使用。
甘露醇:甘露醇呈颗粒或粉末状,在口中溶解时吸热,因而有凉爽感,同时兼具一定的甜味,在口中无砂砾感,因此较适于制备咀嚼片。
甜味剂(优选糖粉):糖粉系指结晶性蔗糖经低温干燥粉碎后而成的白色粉末,其优点在于粘合力强,可用来增加片剂的硬度,并使片剂的表面光滑美观。
本发明的优点为:配比简单,组方搭配合理,促进免疫调解、增加伤口愈合速度,具体为:
本发明以海参为基础料,在其中加入活血化瘀,止血止痛,行气通络,清热润燥的相应中药组分,以提高伤口愈合速度,另外,进一步添加甲壳素,使海参功效、中药功效与甲壳素功效相结合,制备成为咀嚼片使用,较单独的中药治疗、单纯的海参食补或者甲壳素胶丸在治疗伤口的速度上均效果显著。
具体实施方式:
海参营养咀嚼片,其中,包括按照重量份数配置的如下活性组分:
中药料:酸枣仁30-50份,没药20-40份,红花20-40份,竹茹20-40份,橘红10-30份,威灵仙10-30份,地耳草10-30份,猪苓10-30份,丝瓜络10-30份,生地黄10-30份,红藤10-30份,金银花10-30份,黄芩10-30份,石膏10-30份,
基础料:海参300-500份;
附加料:甲壳素3-6份、淀粉10-20份、糊精5-10份、甘露醇3-6份,甜味剂1-4份,微晶纤维素1-4份。
或者,包括按照重量份数配置的如下活性组分:
中药料:酸枣仁30-40份,没药20-30份,红花20-30份,竹茹20-30份,橘红10-20份,威灵仙10-20份,地耳草10-20份,猪苓10-20份,丝瓜络10-20份,生地黄10-20份,红藤10-20份,金银花10-20份,黄芩10-20份,石膏10-20份,
基础料:海参300-400份;
附加料:甲壳素3-5份,淀粉10-15份、糊精5-8份、甘露醇3-5份,甜味剂1-3份,微晶纤维素1-3份。
或者,包括按照重量份数配置的如下活性组分:
中药料:酸枣仁40-50份,没药30-40份,红花30-40份,竹茹30-40份,橘红20-30份,威灵仙20-30份,地耳草20-30份,猪苓20-30份,丝瓜络20-30份,生地黄20-30份,红藤20-30份,金银花20-30份,黄芩20-30份,石膏20-30份,
基础料:海参400-500份;
附加料:甲壳素4-6份,淀粉15-20份、糊精8-10份、甘露醇4-6份,甜味剂2-4份,微晶纤维素2-4份。
或者,包括按照重量份数配置的如下活性组分:
中药料:中药料:酸枣仁35-45份,没药25-35份,红花25-35份,竹茹25-35份,橘红15-25份,威灵仙15-25份,地耳草15-25份,猪苓15-25份,丝瓜络15-25份,生地黄15-25份,红藤15-25份,金银花15-25份,黄芩15-25份,石膏15-25份,
基础料:海参350-450份;
附加料:甲壳素4-5份,淀粉12-18份、糊精6-9份、甘露醇2-5份,甜味剂2-3份,微晶纤维素2-3份。
具体例子1
中药料:酸枣仁50份,没药40份,红花40份,竹茹40份,橘红30份,威灵仙30份,地耳草30份,猪苓30份,丝瓜络30份,生地黄30份,红藤30份,金银花30份,黄芩30份,石膏30份,
基础料:海参500份;
附加料:甲壳素6份、淀粉20份、糊精10份、甘露醇6份,甜味剂4份,微晶纤维素4份。
制备时,A、清洗的步骤:将酸枣仁,没药,红花,竹茹,橘红,威灵仙,地耳草,猪苓,丝瓜络,生地黄,红藤,金银花,黄芩,石膏,使用滚筒式洗药机进行清洗,清洗时间控制在3-5分钟,避免药效流失;
B、润药的步骤:将步骤A清洗干净的中药组分,使用注水式润药机进行润药操作,润药使失水的植物细胞吸水膨胀,为提取工序创造条件;
C、上述组份加重量10倍量乙醇,加热回流提取3次,每次2小时,将3次提取液合并,减压回收乙醇,并浓缩至药液浓度为0.5g生药/mL,抽滤后,滤液的相对密度为20℃时1.08;所述滤液流经体积为10L的大孔吸附树脂柱,之后用10倍树脂柱体积的去离子水或蒸馏水洗脱,再用5倍树脂柱体积的95%乙醇洗脱,收集乙醇洗脱液,去除乙醇溶剂,得到中药药粉,再经80目筛子过筛后,经紫外线杀菌后备用;
D、海参深加工的步骤:鲜活海参,沿腹部从头至尾全剖开,去除内脏,将杂质清洗干净;接着进行冷冻干燥,冷冻温度为-20~-25℃,真空度为5-15Pa,快速冷冻2-3h,将冷冻干燥后的海参放入粉碎机,粉碎10-30min,过60 目筛,得到粗海参粉;将海参粗粉通过气流粉碎机进行超微粉碎,时间2-3h,得到超微海参粉;然后将超微海参粉通过高速剪切超细粉碎机进行纳米化粉碎,粉碎时间为3-5h;
向容器中加入纯净水,使纳米化粉碎后的海参粉与水以1 :5-10 质量比溶解,得到海参浆,称取海参重量0.3-0.4% 的复合蛋白酶,复合蛋白酶为胃蛋白酶的菠萝酶胃的混合物,蛋白酶:菠萝酶的质量比=2:1,使用纯净水将复合蛋白酶溶化后,连同海参浆一起放入酶解罐中,在强度为500-1000w 的微波环境中静置1-2min,进行微波酶解作业,酶解完成后,将酶解液迅速升温度至90℃灭酶10-30min ;完成酶的灭活后,对酶解罐停止加热,将酶解液迅速冷却至常温;酶解罐用纯净水冲洗,冲洗液放入酶解液中;将降温后的酶解液先用普通离心机离心20min,过滤;取滤液,低温超高速离心20min,过滤,得滤液;将滤液通过纳滤以除去盐分;剩余物过100 目筛,得到海参提取液;
E、制备胶囊的步骤:将步骤C所得中药药粉加入到步骤D所得的海参提取液中,中药药粉:海参提取液的重量比为1-1.2:1-1.5;混合均匀后,加入附加料,得到的混合物呈糊状,压片成型,干燥得咀嚼片。
具体例子2
中药料:酸枣仁30份,没药20份,红花20份,竹茹20份,橘红10份,威灵仙10份,地耳草10份,猪苓10份,丝瓜络10份,生地黄10份,红藤10份,金银花10份,黄芩10份,石膏10份,
基础料:海参300份;
附加料:甲壳素3份、淀粉10份、糊精5份、甘露醇3份,甜味剂1份,微晶纤维素1份。
制备时,A、清洗的步骤:将酸枣仁,没药,红花,竹茹,橘红,威灵仙,地耳草,猪苓,丝瓜络,生地黄,红藤,金银花,黄芩,石膏,使用滚筒式洗药机进行清洗,清洗时间控制在3-5分钟,避免药效流失;
B、润药的步骤:将步骤A清洗干净的中药组分,使用注水式润药机进行润药操作,润药使失水的植物细胞吸水膨胀,为提取工序创造条件;
C、上述组份加重量10倍量乙醇,加热回流提取3次,每次2小时,将3次提取液合并,减压回收乙醇,并浓缩至药液浓度为0.5g生药/mL,抽滤后,滤液的相对密度为20℃时1.08;所述滤液流经体积为10L的大孔吸附树脂柱,之后用10倍树脂柱体积的去离子水或蒸馏水洗脱,再用5倍树脂柱体积的95%乙醇洗脱,收集乙醇洗脱液,去除乙醇溶剂,得到中药药粉,再经80目筛子过筛后,经紫外线杀菌后备用;
D、海参深加工的步骤:鲜活海参,沿腹部从头至尾全剖开,去除内脏,将杂质清洗干净;接着进行冷冻干燥,冷冻温度为-20~-25℃,真空度为5-15Pa,快速冷冻2-3h,将冷冻干燥后的海参放入粉碎机,粉碎10-30min,过60 目筛,得到粗海参粉;将海参粗粉通过气流粉碎机进行超微粉碎,时间2-3h,得到超微海参粉;然后将超微海参粉通过高速剪切超细粉碎机进行纳米化粉碎,粉碎时间为3-5h;
向容器中加入纯净水,使纳米化粉碎后的海参粉与水以1 :5-10 质量比溶解,得到海参浆,称取海参重量0.3-0.4% 的复合蛋白酶,复合蛋白酶为胃蛋白酶的菠萝酶胃的混合物,蛋白酶:菠萝酶的质量比=2:1,使用纯净水将复合蛋白酶溶化后,连同海参浆一起放入酶解罐中,在强度为500-1000w 的微波环境中静置1-2min,进行微波酶解作业,酶解完成后,将酶解液迅速升温度至90℃灭酶10-30min ;完成酶的灭活后,对酶解罐停止加热,将酶解液迅速冷却至常温;酶解罐用纯净水冲洗,冲洗液放入酶解液中;将降温后的酶解液先用普通离心机离心20min,过滤;取滤液,低温超高速离心20min,过滤,得滤液;将滤液通过纳滤以除去盐分;剩余物过100 目筛,得到海参提取液;
E、制备胶囊的步骤:将步骤C所得中药药粉加入到步骤D所得的海参提取液中,中药药粉:海参提取液的重量比为1-1.2:1-1.5;混合均匀后,加入附加料,得到的混合物呈糊状,压片成型,干燥得咀嚼片。
具体例子3
中药料:酸枣仁40份,没药30份,红花30份,竹茹30份,橘红20份,威灵仙20份,地耳草20份,猪苓20份,丝瓜络20份,生地黄20份,红藤20份,金银花20份,黄芩20份,石膏20份,
基础料:海参400份;
附加料:甲壳素5份,淀粉15份、糊精8份、甘露醇5份,甜味剂3份,微晶纤维素3份。
制备时,A、清洗的步骤:将酸枣仁,没药,红花,竹茹,橘红,威灵仙,地耳草,猪苓,丝瓜络,生地黄,红藤,金银花,黄芩,石膏,使用滚筒式洗药机进行清洗,清洗时间控制在3-5分钟,避免药效流失;
B、润药的步骤:将步骤A清洗干净的中药组分,使用注水式润药机进行润药操作,润药使失水的植物细胞吸水膨胀,为提取工序创造条件;
C、上述组份加重量10倍量乙醇,加热回流提取3次,每次2小时,将3次提取液合并,减压回收乙醇,并浓缩至药液浓度为0.5g生药/mL,抽滤后,滤液的相对密度为20℃时1.08;所述滤液流经体积为10L的大孔吸附树脂柱,之后用10倍树脂柱体积的去离子水或蒸馏水洗脱,再用5倍树脂柱体积的95%乙醇洗脱,收集乙醇洗脱液,去除乙醇溶剂,得到中药药粉,再经80目筛子过筛后,经紫外线杀菌后备用;
D、海参深加工的步骤:鲜活海参,沿腹部从头至尾全剖开,去除内脏,将杂质清洗干净;接着进行冷冻干燥,冷冻温度为-20~-25℃,真空度为5-15Pa,快速冷冻2-3h,将冷冻干燥后的海参放入粉碎机,粉碎10-30min,过60 目筛,得到粗海参粉;将海参粗粉通过气流粉碎机进行超微粉碎,时间2-3h,得到超微海参粉;然后将超微海参粉通过高速剪切超细粉碎机进行纳米化粉碎,粉碎时间为3-5h;
向容器中加入纯净水,使纳米化粉碎后的海参粉与水以1 :5-10 质量比溶解,得到海参浆,称取海参重量0.3-0.4% 的复合蛋白酶,复合蛋白酶为胃蛋白酶的菠萝酶胃的混合物,蛋白酶:菠萝酶的质量比=2:1,使用纯净水将复合蛋白酶溶化后,连同海参浆一起放入酶解罐中,在强度为500-1000w 的微波环境中静置1-2min,进行微波酶解作业,酶解完成后,将酶解液迅速升温度至90℃灭酶10-30min ;完成酶的灭活后,对酶解罐停止加热,将酶解液迅速冷却至常温;酶解罐用纯净水冲洗,冲洗液放入酶解液中;将降温后的酶解液先用普通离心机离心20min,过滤;取滤液,低温超高速离心20min,过滤,得滤液;将滤液通过纳滤以除去盐分;剩余物过100 目筛,得到海参提取液;
E、制备胶囊的步骤:将步骤C所得中药药粉加入到步骤D所得的海参提取液中,中药药粉:海参提取液的重量比为1-1.2:1-1.5;混合均匀后,加入附加料,得到的混合物呈糊状,压片成型,干燥得咀嚼片。
本发明配比简单,组方搭配合理,促进免疫调解、增加伤口愈合速度,具体为:本发明以海参为基础料,在其中加入活血化瘀,止血止痛,行气通络,清热润燥的相应中药组分,以提高伤口愈合速度,另外,进一步添加甲壳素,使海参功效、中药功效与甲壳素功效相结合,制备成为咀嚼片使用,较单独的中药治疗、单纯的海参食补或者甲壳素胶丸在治疗伤口的速度上均效果显著。
Claims (4)
1.一种海参营养咀嚼片,其特征在于,包括按照重量份数配置的如下活性组分:
中药料:酸枣仁30-50份,没药20-40份,红花20-40份,竹茹20-40份,橘红10-30份,威灵仙10-30份,地耳草10-30份,猪苓10-30份,丝瓜络10-30份,生地黄10-30份,红藤10-30份,金银花10-30份,黄芩10-30份,石膏10-30份,
基础料:海参300-500份;
附加料:甲壳素3-6份、淀粉10-20份、糊精5-10份、甘露醇3-6份,甜味剂1-4份,微晶纤维素1-4份。
2.根据权利要求1所述海参营养咀嚼片,其特征在于,包括按照重量份数配置的如下活性组分:
中药料:酸枣仁30-40份,没药20-30份,红花20-30份,竹茹20-30份,橘红10-20份,威灵仙10-20份,地耳草10-20份,猪苓10-20份,丝瓜络10-20份,生地黄10-20份,红藤10-20份,金银花10-20份,黄芩10-20份,石膏10-20份,
基础料:海参300-400份;
附加料:甲壳素3-5份,淀粉10-15份、糊精5-8份、甘露醇3-5份,甜味剂1-3份,微晶纤维素1-3份。
3.根据权利要求1所述海参营养咀嚼片,其特征在于,包括按照重量份数配置的如下活性组分:
中药料:酸枣仁40-50份,没药30-40份,红花30-40份,竹茹30-40份,橘红20-30份,威灵仙20-30份,地耳草20-30份,猪苓20-30份,丝瓜络20-30份,生地黄20-30份,红藤20-30份,金银花20-30份,黄芩20-30份,石膏20-30份,
基础料:海参400-500份;
附加料:甲壳素4-6份,淀粉15-20份、糊精8-10份、甘露醇4-6份,甜味剂2-4份,微晶纤维素2-4份。
4.根据权利要求1所述海参营养咀嚼片,其特征在于,包括按照重量份数配置的如下活性组分:
中药料:中药料:酸枣仁35-45份,没药25-35份,红花25-35份,竹茹25-35份,橘红15-25份,威灵仙15-25份,地耳草15-25份,猪苓15-25份,丝瓜络15-25份,生地黄15-25份,红藤15-25份,金银花15-25份,黄芩15-25份,石膏15-25份,
基础料:海参350-450份;
附加料:甲壳素4-5份,淀粉12-18份、糊精6-9份、甘露醇2-5份,甜味剂2-3份,微晶纤维素2-3份。
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