CN104491818A - Formula for treating rheumatoid rheumatic arthritis and preparation method thereof - Google Patents

Formula for treating rheumatoid rheumatic arthritis and preparation method thereof Download PDF

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CN104491818A
CN104491818A CN201410854731.2A CN201410854731A CN104491818A CN 104491818 A CN104491818 A CN 104491818A CN 201410854731 A CN201410854731 A CN 201410854731A CN 104491818 A CN104491818 A CN 104491818A
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parts
radix
rhizoma
formula
semen strychni
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刘一泰
刘国村
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237Notopterygium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/56Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716Clematis (leather flower)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger

Abstract

The invention discloses a formula for treating rheumatoid rheumatic arthritis and a preparation method thereof. In the formula, the following components are comprised: monkshood, radix aconiti agrestis, saposhnicovia divaricata, Chinese angelica, frankincense, myrrh, ephedra, earthworms, dried body of ground beetle, rhizoma zingiberis, notopterygium root, pawpaws, ligusticum wallichii, radix cyathulae, cassia twig, radix clematidis, fructus citri sarcodactyli, eucommia ulmoides and semen strychni. The formula is prepared by processing the components into powder, mixing, drying, performing enzyme deactivation and screening. The formula for treating rheumatoid rheumatic arthritis disclosed by the invention adopts natural medical components which are matched and mixed to achieve effects of mutually permeating, is free of side effect and quick in effect-taking. According to the clinical practice of hundreds of years, the formula has an effective rate of 100%, and has a remarkable curative effect on patients with rheumatism and rheumatoid arthritis, pains in neck, shoulders, waist and legs.

Description

Rheumatic rheumatoid arthritis treatment formula and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of rheumatic rheumatoid arthritis treatment formula and preparation method thereof.
Background technology
Rheumatoid and rheumatic arthritis are a kind of based on the whole body chronic disease of the non-infectious inflammation of joint and periarticular tissue, and in Chinese medicine, be called that numbness is sick, be one of common clinical and difficult treatment.Cardinal symptom can show miserable, pain, the enlargement at the place such as limbs, joint, and can aggravate with ambient weather change, and it is anxious that severe one can cause joint contraction, and joint stuffiness, is even entered internal organs by meridians, occur that internal organs QI and blood hinders the syndrome of closing.Its cause of disease mostly is caused by wind-cold damp pathogen invasion and attack human body, and partially wins different with its invasion and attack and make clinical syndrome different.With ailment said due to cold or exposure victor for migratory arthralgia, cold-evil victor is arthralgia aggravated by cold, and damp victor is damp arthralgia.Wherein the clinical manifestation of damp arthralgia be limbs joint pain, weigh, swelling, limitation of activity, sore spot is fixing not to be moved, or numbness of the skin is meciless, and normal touching difficulty is more.
The anti-treating rheumatic arthritis of motherland's medical science and rheumatoid arthritis disease with a long history, successive dynasties have accumulated rich experiences, at present, some are developed by single medicinal material as Radix Tripterygii Wilfordii, Tripterygium hypoglaucum and by Radix Angelicae Sinensis, Scorpio, Scolopendra, Nidus Vespae, Eupolyphaga Seu Steleophaga and Caulis Sinomenii, Radix Aconiti Lateralis Preparata, the medicines such as Cornu Cervi Pantotrichum are the compound preparation of main composition, good effect is achieved to the control of rheumatic arthritis and rheumatoid arthritis disease, but the side effect of above-mentioned Chinese medicine composition is more, as damaged reproductive system function, endocrine dysfunction and stimulating gastrointestinal mucosa is caused to cause nausea, vomiting, stomachache, the gastrointestinal side effects such as diarrhoea, hepatic injury can be caused, glutamate pyruvate transaminase in blood is raised, suppress bone marrow hematogenesis, make leukocyte, thrombocytopenia etc., and most of Chinese medicine composition only can take stopgap measures, fundamentally cannot treat rheumatoid arthritis disease, temporarily can only slow down pain, once discontinue medication, will again fall ill.
Summary of the invention
For the deficiencies in the prior art, the invention provides a kind of rheumatic rheumatoid arthritis treatment formula and preparation method thereof, adopt natural drug material composition, reduce untoward reaction, curative effect is high, non-evident effect.
The technical solution adopted for the present invention to solve the technical problems is:
A kind of rheumatic rheumatoid arthritis treatment formula, be made up of Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Saposhnikoviae, Radix Angelicae Sinensis, Olibanum, Myrrha, Herba Ephedrae, Pheretima, eupolyphaga, Rhizoma Zingiberis, Rhizoma Et Radix Notopterygii, Fructus Chaenomelis, Rhizoma Chuanxiong, Radix Cyathulae, Ramulus Cinnamomi, Radix Clematidis, finger citron sliced, the Cortex Eucommiae and Semen Strychni, the mass parts ratio that wherein each component uses is: Radix Aconiti 10 ~ 20 parts; Radix Aconiti Kusnezoffii 10 ~ 20 parts; Radix Saposhnikoviae 10 ~ 20 parts; Radix Angelicae Sinensis 10 ~ 20 parts; Olibanum 10 ~ 20 parts; Myrrha 10 ~ 20 parts; 12 ~ 18 parts, Herba Ephedrae; Pheretima 15 ~ 20 parts; Eupolyphaga 15 ~ 20 parts; Rhizoma Zingiberis 15 ~ 20 parts; Rhizoma Et Radix Notopterygii 10 ~ 20 parts; Fructus Chaenomelis 10 ~ 20 parts; Rhizoma Chuanxiong 10 ~ 20 parts; Radix Cyathulae 15 ~ 20 parts; Ramulus Cinnamomi 10 ~ 20 parts; Radix Clematidis 10 ~ 20 parts; Finger citron sliced 10 ~ 20 parts; The Cortex Eucommiae 10 ~ 20 parts; Semen Strychni 200 ~ 300 parts.
Above-mentioned rheumatic rheumatoid arthritis treatment formula, preparation method concrete steps are as follows:
(1) get the raw materials ready: get sand, put in pot and make popular, add and pick clean Semen Strychni, fry to being buff and heaving, take out, sieve removes sand, unhairing, levigation, and powder soaks to filter for 24 hours and obtains Semen Strychni Pulveratum in Radix Glycyrrhizae extract, for subsequent use; Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Saposhnikoviae, Herba Ephedrae, Rhizoma Et Radix Notopterygii, Rhizoma Chuanxiong, Radix Clematidis and Radix Cyathulae are carried out concocting into powder; Pheretima and eupolyphaga yellow wine are mixed thoroughly slightly profit, put in pot with slow fire fry slightly see focal spot to yellow time, namely take out spreading for cooling, levigation; Radix Angelicae Sinensis, Herba Ephedrae, Olibanum, Myrrha, Rhizoma Zingiberis, Fructus Chaenomelis, Ramulus Cinnamomi, finger citron sliced and the Cortex Eucommiae are carried out concocting into powder;
(2) by above-mentioned various powder mixing, then be positioned in Enzyme-deactivation dryer and heat, temperature controls between 200-220 DEG C, make moisture lower than 5%, play enzyme denaturing effect simultaneously, then mixture is delivered to pulverizer and carry out pulverization process, obtain 80-500 object micropowder.
In rheumatic rheumatoid arthritis treatment formula of the present invention: 1, Radix Aconiti: expelling wind and removing dampness, antalgic.Have a pain for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type, be used for the treatment of the disease such as anemofrigid-damp arthralgia, arthralgia.2, Radix Aconiti Kusnezoffii: search wind prevailing over dampness, dispersing cold for relieving pain, opens expectorant, detumescence.Control anemofrigid-damp arthralgia, paralysis due to windstroke, tetanus, wind syndrome of head, coldness and pain in the epigastrium, accumulation of phlegm in the hypochondrium, air parcel, cold-dysentery, sore throat, carbuncle, furuncle, scrofula.3, Radix Saposhnikoviae: expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion is jerked surely.4, Radix Angelicae Sinensis: enrich blood invigorate blood circulation, rheumatic arthralgia, injury from falling down, ulcer sores.5, Olibanum: have more significant analgesic activity and bacteriostasis.6, Myrrha: there is loose blood blood stasis removing, effect of subduing swelling and relieving pain.7, Herba Ephedrae: diaphoresis cold expelling, inducing diuresis to remove edema, is used for the treatment of edema due to wind pathogen edema and rheumatic arthralgia.8, Pheretima: cure mainly high fanatical dry, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, hemiplegia etc.9, eupolyphaga: removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.10, Rhizoma Zingiberis: warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, dampness expectorant, and warming the lung to resolve fluid-retention, cures mainly coldness and pain in the epigastrium; Vomiting; Have loose bowels, YANG-depletion is fainted inverse; Cold fluid-retention is breathed with cough; Arthralgia due to cold-dampnes.11, Rhizoma Et Radix Notopterygii: loose exterior cold, wind-damp dispelling, sharp joint, cures mainly anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore.12, Fructus Chaenomelis: swell and ache for rheumatic arthralgia, the contracture of muscle arteries and veins, beriberi.Fructus Chaenomelis has good relaxing muscles and tendons and activating QI and blood in the collateral effect, and energy removing dampness, by dispelling the wind and dampness pathogens arthralgia pain is commonly used.13, Rhizoma Chuanxiong: for pain in chest and hypochondrium, rheumatic arthralgia, lump in the abdomen lumps, and skin infection swells and ache, and falls and flutters the pain of injury.14, Radix Cyathulae: dispel the wind, dampness removing, stimulates the menstrual flow, and invigorates blood circulation.Dispelling the wind and dampness pathogens lumbocrural pain, foot flaccidity clonic spasm of the muscle.15, Ramulus Cinnamomi: diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.16, Radix Clematidis: cure mainly gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, chills and pain of the waist and kness, the contracture of muscle arteries and veins, joint stuffiness.17, finger citron sliced: have activating QI to eliminate phlegm, preventing or arresting vomiting relieving distension, the liver soothing and the spleen invigorating, stomach function regulating effect.18, the Cortex Eucommiae: invigorating the liver and kidney, bone and muscle strengthening, controls spinal column ache, foot and knee flaccidity.19, Semen Strychni: removing obstruction in the collateral to relieve pain, cures mainly rheumatoid arthritis stubborn, contracture numbness, anemofrigid-damp arthralgia, general joint contracture, numbness.
Three large compositions are mainly divided in rheumatic rheumatoid arthritis treatment formula of the present invention, Semen Strychni, Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Saposhnikoviae, Herba Ephedrae, Rhizoma Et Radix Notopterygii, Rhizoma Chuanxiong, Radix Clematidis and Radix Cyathulae are for curing mainly composition, Pheretima, eupolyphaga, Radix Angelicae Sinensis, Myrrha, Herba Ephedrae, Rhizoma Zingiberis, Fructus Chaenomelis and Ramulus Cinnamomi are auxiliary treatment composition, and finger citron sliced and the Cortex Eucommiae are liver detoxification composition.
Rheumatic rheumatoid arthritis treatment formula of the present invention all adopts natural medicinal ingredients, the mutual compatibility of various important component is utilized to be in harmonious proportion, reach each composition nature and flavor to interpenetrate, have no side effect, instant effect, through the clinical practice of upper a century, none example is invalid, has significant curative effect to rheumatism, patient with rheumatoid arthritis and neck, shoulder, waist, skelalgia.
Detailed description of the invention
A kind of rheumatic rheumatoid arthritis treatment formula, be made up of Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Saposhnikoviae, Radix Angelicae Sinensis, Olibanum, Myrrha, Herba Ephedrae, Pheretima, eupolyphaga, Rhizoma Zingiberis, Rhizoma Et Radix Notopterygii, Fructus Chaenomelis, Rhizoma Chuanxiong, Radix Cyathulae, Ramulus Cinnamomi, Radix Clematidis, finger citron sliced, the Cortex Eucommiae and Semen Strychni, the mass parts ratio that wherein each component uses is: Radix Aconiti 15 parts; Radix Aconiti Kusnezoffii 15 parts; Radix Saposhnikoviae 15 parts; Radix Angelicae Sinensis 15 parts; Olibanum 15 parts; Myrrha 15 parts; 16 parts, Herba Ephedrae; Pheretima 18 parts; 18 parts, upper unit; Rhizoma Zingiberis 18 parts; Rhizoma Et Radix Notopterygii 15 parts; Fructus Chaenomelis 15 parts; Rhizoma Chuanxiong 15 parts; Radix Cyathulae 18 parts; Ramulus Cinnamomi 15 parts; Radix Clematidis 15 parts; Finger citron sliced 15 parts; The Cortex Eucommiae 15 parts; Semen Strychni 250 parts.
Above-mentioned rheumatic rheumatoid arthritis treatment formula, preparation method concrete steps are as follows:
(1) get the raw materials ready: get sand, put in pot and make popular, add and pick clean Semen Strychni, fry to being buff and heaving, take out, sieve removes sand, unhairing, levigation, and powder soaks to filter for 24 hours and obtains Semen Strychni Pulveratum in Radix Glycyrrhizae extract, for subsequent use; Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Saposhnikoviae, Herba Ephedrae, Rhizoma Et Radix Notopterygii, Rhizoma Chuanxiong, Radix Clematidis and Radix Cyathulae are carried out concocting into powder; Pheretima and eupolyphaga yellow wine are mixed thoroughly slightly profit, put in pot with slow fire fry slightly see focal spot to yellow time, namely take out spreading for cooling, levigation; Radix Angelicae Sinensis, Herba Ephedrae, Olibanum, Myrrha, Rhizoma Zingiberis, Fructus Chaenomelis, Ramulus Cinnamomi, finger citron sliced and the Cortex Eucommiae are carried out concocting into powder;
(2) by above-mentioned various powder mixing, then be positioned in Enzyme-deactivation dryer and heat, temperature controls between 200-220 DEG C, make moisture lower than 5%, play enzyme denaturing effect simultaneously, then mixture is delivered to pulverizer and carry out pulverization process, obtain 80-500 object micropowder.

Claims (2)

1. a rheumatic rheumatoid arthritis treatment formula, it is characterized in that being made up of Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Saposhnikoviae, Radix Angelicae Sinensis, Olibanum, Myrrha, Herba Ephedrae, Pheretima, eupolyphaga, Rhizoma Zingiberis, Rhizoma Et Radix Notopterygii, Fructus Chaenomelis, Rhizoma Chuanxiong, Radix Cyathulae, Ramulus Cinnamomi, Radix Clematidis, finger citron sliced, the Cortex Eucommiae and Semen Strychni, the mass parts ratio that wherein each component uses is: Radix Aconiti 10 ~ 20 parts; Radix Aconiti Kusnezoffii 10 ~ 20 parts; Radix Saposhnikoviae 10 ~ 20 parts; Radix Angelicae Sinensis 10 ~ 20 parts; Olibanum 10 ~ 20 parts; Myrrha 10 ~ 20 parts; 12 ~ 18 parts, Herba Ephedrae; Pheretima 15 ~ 20 parts; Eupolyphaga 15 ~ 20 parts; Rhizoma Zingiberis 15 ~ 20 parts; Rhizoma Et Radix Notopterygii 10 ~ 20 parts; Fructus Chaenomelis 10 ~ 20 parts; Rhizoma Chuanxiong 10 ~ 20 parts; Radix Cyathulae 15 ~ 20 parts; Ramulus Cinnamomi 10 ~ 20 parts; Radix Clematidis 10 ~ 20 parts; Finger citron sliced 10 ~ 20 parts; The Cortex Eucommiae 10 ~ 20 parts; Semen Strychni 200 ~ 300 parts.
2. rheumatic rheumatoid arthritis treatment formula according to claim 1, is characterized in that preparation method concrete steps are as follows:
(1) get the raw materials ready: get sand, put in pot and make popular, add and pick clean Semen Strychni, fry to being buff and heaving, take out, sieve removes sand, unhairing, levigation, and powder soaks to filter for 24 hours and obtains Semen Strychni Pulveratum in Radix Glycyrrhizae extract, for subsequent use; Radix Aconiti, Radix Aconiti Kusnezoffii, Radix Saposhnikoviae, Herba Ephedrae, Rhizoma Et Radix Notopterygii, Rhizoma Chuanxiong, Radix Clematidis and Radix Cyathulae are carried out concocting into powder; Pheretima and eupolyphaga yellow wine are mixed thoroughly slightly profit, put in pot with slow fire fry slightly see focal spot to yellow time, namely take out spreading for cooling, levigation; Radix Angelicae Sinensis, Herba Ephedrae, Olibanum, Myrrha, Rhizoma Zingiberis, Fructus Chaenomelis, Ramulus Cinnamomi, finger citron sliced and the Cortex Eucommiae are carried out concocting into powder;
(2) by above-mentioned various powder mixing, then be positioned in Enzyme-deactivation dryer and heat, temperature controls between 200-220 DEG C, make moisture lower than 5%, play enzyme denaturing effect simultaneously, then mixture is delivered to pulverizer and carry out pulverization process, obtain 80-500 object micropowder.
CN201410854731.2A 2014-12-15 2014-12-15 Formula for treating rheumatoid rheumatic arthritis and preparation method thereof Pending CN104491818A (en)

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