CN104490616A - Application of natural organic carboxylate laminine chelates in fiber - Google Patents
Application of natural organic carboxylate laminine chelates in fiber Download PDFInfo
- Publication number
- CN104490616A CN104490616A CN201410753504.0A CN201410753504A CN104490616A CN 104490616 A CN104490616 A CN 104490616A CN 201410753504 A CN201410753504 A CN 201410753504A CN 104490616 A CN104490616 A CN 104490616A
- Authority
- CN
- China
- Prior art keywords
- laminine
- natural organic
- chelates
- ion
- organic carboxylate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- MXNRLFUSFKVQSK-UHFFFAOYSA-N 2-Amino-6-(trimethylazaniumyl)hexanoate Chemical compound C[N+](C)(C)CCCCC(N)C([O-])=O MXNRLFUSFKVQSK-UHFFFAOYSA-N 0.000 title claims abstract description 48
- 239000000835 fiber Substances 0.000 title claims abstract description 19
- 150000007942 carboxylates Chemical class 0.000 title abstract 7
- 230000003115 biocidal effect Effects 0.000 claims abstract description 23
- 239000013522 chelant Substances 0.000 claims abstract description 23
- 235000015097 nutrients Nutrition 0.000 claims abstract description 11
- -1 halogen anions Chemical class 0.000 claims abstract description 10
- 238000004519 manufacturing process Methods 0.000 claims abstract description 5
- 150000007524 organic acids Chemical class 0.000 claims description 31
- 239000002253 acid Substances 0.000 claims description 11
- 229910052709 silver Inorganic materials 0.000 claims description 7
- 239000004332 silver Substances 0.000 claims description 7
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 claims description 5
- 230000001228 trophic effect Effects 0.000 claims description 5
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 4
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 claims description 4
- 241000191967 Staphylococcus aureus Species 0.000 claims description 4
- 150000001450 anions Chemical class 0.000 claims description 4
- 229910001425 magnesium ion Inorganic materials 0.000 claims description 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims description 3
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 3
- 229930003268 Vitamin C Natural products 0.000 claims description 3
- 125000000539 amino acid group Chemical group 0.000 claims description 3
- 150000001768 cations Chemical class 0.000 claims description 3
- POULHZVOKOAJMA-UHFFFAOYSA-M dodecanoate Chemical compound CCCCCCCCCCCC([O-])=O POULHZVOKOAJMA-UHFFFAOYSA-M 0.000 claims description 3
- 229940070765 laurate Drugs 0.000 claims description 3
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims description 3
- 229910052761 rare earth metal Inorganic materials 0.000 claims description 3
- 229940095064 tartrate Drugs 0.000 claims description 3
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims description 3
- 235000019154 vitamin C Nutrition 0.000 claims description 3
- 239000011718 vitamin C Substances 0.000 claims description 3
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims description 2
- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 claims description 2
- 241000588724 Escherichia coli Species 0.000 claims description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 claims description 2
- LCKIEQZJEYYRIY-UHFFFAOYSA-N Titanium ion Chemical compound [Ti+4] LCKIEQZJEYYRIY-UHFFFAOYSA-N 0.000 claims description 2
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 229910001424 calcium ion Inorganic materials 0.000 claims description 2
- 229940047608 chelated magnesium Drugs 0.000 claims description 2
- 229910001431 copper ion Inorganic materials 0.000 claims description 2
- 239000013078 crystal Substances 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 9
- 230000000845 anti-microbial effect Effects 0.000 abstract description 7
- 229910021645 metal ion Inorganic materials 0.000 abstract description 5
- 230000007246 mechanism Effects 0.000 abstract description 4
- 230000000813 microbial effect Effects 0.000 abstract description 4
- 244000005700 microbiome Species 0.000 abstract description 3
- 229910052736 halogen Inorganic materials 0.000 abstract description 2
- 230000029058 respiratory gaseous exchange Effects 0.000 abstract description 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 125000002091 cationic group Chemical group 0.000 abstract 1
- 239000002131 composite material Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 description 18
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 6
- 235000001014 amino acid Nutrition 0.000 description 4
- 150000001413 amino acids Chemical class 0.000 description 4
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 230000000774 hypoallergenic effect Effects 0.000 description 4
- 235000016709 nutrition Nutrition 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 238000011160 research Methods 0.000 description 4
- 230000004071 biological effect Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000035764 nutrition Effects 0.000 description 3
- 235000018102 proteins Nutrition 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 206010020772 Hypertension Diseases 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-M L-ascorbate Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] CIWBSHSKHKDKBQ-JLAZNSOCSA-M 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 210000000170 cell membrane Anatomy 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 238000012790 confirmation Methods 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 150000005838 radical anions Chemical class 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 206010008111 Cerebral haemorrhage Diseases 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 101710088194 Dehydrogenase Proteins 0.000 description 1
- 235000017858 Laurus nobilis Nutrition 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241000199919 Phaeophyceae Species 0.000 description 1
- 229920000297 Rayon Polymers 0.000 description 1
- 235000018167 Reynoutria japonica Nutrition 0.000 description 1
- 240000001341 Reynoutria japonica Species 0.000 description 1
- 241000195474 Sargassum Species 0.000 description 1
- 241000033695 Sige Species 0.000 description 1
- 244000125380 Terminalia tomentosa Species 0.000 description 1
- 235000005212 Terminalia tomentosa Nutrition 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 229960001126 alginic acid Drugs 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 239000000783 alginic acid Substances 0.000 description 1
- 150000004781 alginic acids Chemical class 0.000 description 1
- 229940077927 altace Drugs 0.000 description 1
- 150000001449 anionic compounds Chemical class 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000003276 anti-hypertensive effect Effects 0.000 description 1
- 230000000702 anti-platelet effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000003139 biocide Substances 0.000 description 1
- 239000012496 blank sample Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 230000002079 cooperative effect Effects 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 230000000875 corresponding effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 239000003792 electrolyte Substances 0.000 description 1
- 239000013538 functional additive Substances 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000002779 inactivation Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 229910001412 inorganic anion Inorganic materials 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- HDACQVRGBOVJII-JBDAPHQKSA-N ramipril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](C[C@@H]2CCC[C@@H]21)C(O)=O)CC1=CC=CC=C1 HDACQVRGBOVJII-JBDAPHQKSA-N 0.000 description 1
- 150000002910 rare earth metals Chemical class 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000005215 recombination Methods 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses application of natural organic carboxylate laminine chelates as antibiotic nutrients in a fiber. One or more natural organic carboxylate laminine chelates are independently used, and are applied to the field of manufacturing of antibiotic nutrient fibers as the antibiotic nutrients. The natural organic carboxylate laminine chelates are composite mechanisms, so that, on one hand, the natural organic carboxylate laminine chelates carry with cationic groups, and can electrostatically adsorb microorganisms such as bacteria with negative charges on a cytomembrane to inhibit the breathing function of microbial cells, resulting in contact death; the metal ions can form a complex or chelate together with an active group in the cell; and the microorganisms cannot breed or even die. Compared with halogen anions in the prior art, the natural organic carboxylate laminine chelates have relatively good biocompatibility and biodegradability, and no toxic or side effect, and therefore, the natural organic carboxylate laminine chelates have good broad-spectrum antimicrobial capability and a skin-nourishing function.
Description
Technical field
The present invention relates generally to one and natural organic acids root laminine chelate is used as antibiosis nutrient, and the main antibiosis trophic fiber that is used as manufactures field.
Background technology
Laminine is distinctive a kind of ocean nonprotein amino acid with biological hypertension activity in Sargassum, can reduce cholesterol, reduces blood fat, anti-platelet aggregation, prevents blood vessel scleratheroma, effectively the generation of prophylaxis of hypertension and cerebral hemorrhage, safe and efficient, have no side effect.Metal ion has maintenance electrolyte balance in vivo, form the multiple biological activity such as protein molecule active center, antimicrobial infringement, natural organic acids root laminine metallo-chelate then has the dual biological activity of natural organic acids root laminine and metal concurrently, is the newtype drug urgently leaved for development and the functional additive that have no report.Within 1964, Japanese bamboo Ben Changsong finds to there is a kind of aminoacid with antihypertensive activity in natural organic acids root Brown algae (i.e. Thallus Laminariae (Thallus Eckloniae)), called after laminine (Laminine) after confirmation structure, but because the content of laminine in Thallus Laminariae (Thallus Eckloniae) is very low, so not only there is no commercialization at present, biological activity aspect is also only limitted to its research; After this progress is slow, until nineteen ninety-five, the people such as Sun Shixi [research [J] of Altace Ramipril-natural organic acids root laminine synthetic method. Shandong medical industry, 1995,14 (2): 7-8] propose the chemical synthesis process of laminine; Patent CN200410024504.3 discloses a kind of cleanly production and application process of crude drug-N-trimethyl lysine; On the former basis, patent CN200610069978.9 discloses a kind of clean method for producing of high-purity laminine, and the research of laminine and commercial value are promoted further.
Although the existing research of natural organic acids root laminine metallo-chelate, belongs to active anticancer field, be used as antibiosis nutrient and be used for fiber and be fabricated onto and have no report at present.
Summary of the invention
The invention discloses a kind of natural organic acids root laminine chelate as the application in the fibre of antibiosis nutrient, it is mainly used as the fields such as antibiosis, diseases prevention, hypo-allergenic, extra-nutrition, and natural organic acids root laminine chelate of the present invention has good broad spectrum antimicrobial ability and conveying nutritional capacity.
Its technical solution is:
Organic acid laminine chelate is as the application of antibiosis nutrient, and the molecular formula of described organic acid laminine chelate is as (1-1):
Wherein, Y represents anion during organic acid laminine chelate cation formation crystal, and described anion comprises citrate, tartrate anion, maleate, laurate, Petiolus Trachycarpi acid group, lactate, Vitamin C acid group or amino acid group; M represents calcium ion, magnesium ion, copper ion, silver ion, titanium ion or mixed light rare earth ion; The described antibiosis trophic fiber that is applied as manufactures field; Described organic acid laminine chelate shared percent by weight in the manufacture of antibiosis trophic fiber is 1-10%.
As a preferred version of the present invention, above-mentioned M is the mixture of magnesium ion and silver ion, the organic acid laminine chelated magnesium formed and organic acid laminine chelating silver are 99.3% to staphylococcus aureus bacteriostasis rate, are 98.8% to escherichia coli bacteriostasis rate.
The reaction mechanism of organic acid laminine chelate of the present invention is as follows:
From antimicrobial mechanism, natural organic acids root laminine chelate is recombination mechanism, on the one hand natural organic acids root laminine chelate carries cation group, can the Antimicrobial microbial cell such as the electronegative antibacterial of Electrostatic Absorption cell membrane breathing function and cause " contact is dead "; Also can diffuse in cell membrane, suppress microbial cell dehydrogenase, oxidase effect, make its inactivation; The metal ion of organic chelated state, more easily near cell, can form bonding relationships with active group in microbial cell, and makes microorganism irreproducible even dead, and two kinds of effects may exist in cooperative effect.Meanwhile, natural organic acids root maintains weakly alkaline environment, and alginic acid has skin-moisturizing, skin performance, and selected metal ion is biological element, three's synergistic, and fiber can be made to have antibiosis, diseases prevention, hypo-allergenic, extra-nutrition effect.
Natural organic acids root laminine chelate of the present invention is as the application of antibiosis nutrient, its experimental result in an embodiment have also been obtained corresponding confirmation, compared with traditional antibiosis nutrient, natural organic acids root laminine of the present invention is marine natural non-protein amino acid, the chelate formed with biological essential metal element is also environmentally friendly antibiotic, has opened up new purposes direction for making full use of this valuable marine natural biological active substance.
Natural organic acids root laminine and halogen anion of the prior art, the inorganic anion such as sulfate radical, nitrate anion, phosphate radical, acetate, hydroxyl are compared, and have better biocompatibility, biodegradable, have no side effect.Therefore, natural organic acids root laminine chelate has good broad spectrum antimicrobial ability and the biocompatibility to skin.
Accompanying drawing explanation
Below in conjunction with accompanying drawing, explanation clear, complete is further done to the present invention:
Fig. 1 is that the embodiment of the present invention 1 is to colibacillary antibacterial loop graph and antibacterial circle diameter d value (inhibition zone method).
Detailed description of the invention
The invention discloses a kind of natural organic acids root laminine chelate as the application in the fibre of antibiosis nutrient, in order to make advantage of the present invention, technical scheme clearly, clearly, below in conjunction with specific embodiment, explanation clear, complete is further done to the present invention.
Raw material selected by the present invention is all bought by commercial channel and is obtained.
In order to further illustrate object of the present invention, illustrate especially exemplified by following examples:
Embodiment 1
Petiolus Trachycarpi acid group laminine chelating silver is made into 20% aqueous solution, make an addition to mix homogeneously in spray webbing serosity, Petiolus Trachycarpi acid group laminine chelating silver content is more than or equal to 1%, be less than or equal to 10%, the regenerated fiber of preparation is to gram negative bacteria---and staphylococcus aureus bacteriostasis rate is 97.8%, to gram positive bacteria---escherichia coli bacteriostasis rate is 96.3%, because of the non-protein ocean aminoacid containing organic monoacid combination, therefore have skin nutrition, comfortable, inhale smelly, antianaphylaxis function, and product has biodegradable.As shown in Figure 1, general bacteriostatic diameter is more than or equal to 10mm, is just effective biocide, and antibacterial circle diameter 31mm herein, illustrates that sterilizing ability is larger.This illustration understands Petiolus Trachycarpi acid group laminine chelating silver existing sterilizing disease-preventing effect, again nutritious skin, hypo-allergenic effect.
Embodiment 2
Difference from Example 1 is: respectively Laurel Petiolus Trachycarpi acid radical anion is replaced to citrate, tartrate anion, maleate, laurate, amino acid group, Vitamin C acid radical anion, for the preparation of antibiosis nutrition regenerated fiber, effect is close with embodiment 4.
Embodiment 3
Difference from Example 1 is: respectively silver ion is replaced in the metal ions such as calcium, magnesium, copper, zinc, titanium, rare earth one or more, for the preparation of functional regeneration fiber, effect is close with embodiment 1.For regenerated viscose fiber, experimental result sees table 1 (blank sample is the same matrix fiber not adding functional component).
Table 1
Illustrate: antibiosis ability 1 (%) refers to gram negative bacteria---staphylococcus aureus bacteriostasis rate; Antibiosis ability 2 (%) is to gram positive bacteria---escherichia coli bacteriostasis rate; Skin nutrition evaluation, hypo-allergenic evaluation refer to employing 5 grades of assessment methods, and plus sige is more, and effect is better, 3 plus siges and be judged to effectively above.
Embodiment 4
20% aqueous solution is made into after being mixed by 1:1 with polyhexamethylene guanidine by Petiolus Trachycarpi acid group laminine chelating silver, make an addition to mix homogeneously in spray webbing serosity, Petiolus Trachycarpi acid group laminine chelating silver content is more than or equal to 1%, be less than or equal to 10%, the regenerated fiber of preparation is to gram negative bacteria---and staphylococcus aureus bacteriostasis rate is 99.3%, to gram positive bacteria---escherichia coli bacteriostasis rate is 97.6%, have comfortable, inhale smelly, antianaphylaxis function, and biodegradable.
The natural organic acids root laminine chelate that the present invention prepares has good broad spectrum antimicrobial ability and the biocompatibility to skin.
Claims (2)
1. organic acid laminine chelate is as the application of antibiosis nutrient, and the molecular formula of described organic acid laminine chelate is as (1-1):
Wherein, Y represents anion during organic acid laminine chelate cation formation crystal, and described anion comprises the one in citrate, tartrate anion, maleate, laurate, Petiolus Trachycarpi acid group, lactate, Vitamin C acid group or amino acid group;
M represents the one in calcium ion, magnesium ion, copper ion, silver ion, titanium ion or mixed light rare earth ion; The described antibiosis trophic fiber that is applied as manufactures field, and described organic acid laminine chelate shared percent by weight in the manufacture of antibiosis trophic fiber is 1-10%.
2. application according to claim 1, it is characterized in that: described M is the mixture of magnesium ion and silver ion, the organic acid laminine chelated magnesium formed and organic acid laminine chelating silver are 99.3% to staphylococcus aureus bacteriostasis rate, are 98.8% to escherichia coli bacteriostasis rate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410753504.0A CN104490616B (en) | 2014-12-10 | 2014-12-10 | The application of natural organic acids root laminine chelate in the fibre |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410753504.0A CN104490616B (en) | 2014-12-10 | 2014-12-10 | The application of natural organic acids root laminine chelate in the fibre |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104490616A true CN104490616A (en) | 2015-04-08 |
| CN104490616B CN104490616B (en) | 2018-05-29 |
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| CN201410753504.0A Expired - Fee Related CN104490616B (en) | 2014-12-10 | 2014-12-10 | The application of natural organic acids root laminine chelate in the fibre |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104490616B (en) |
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- 2014-12-10 CN CN201410753504.0A patent/CN104490616B/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| 孔合心: "昆布氨酸的纯化以及吸湿性、抗菌性研究", 《中国优秀硕士学位论文全文数据库 工程科技I辑》 * |
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| CN104490616B (en) | 2018-05-29 |
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