CN104490486A - Spring type animal beating device and method - Google Patents
Spring type animal beating device and method Download PDFInfo
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- CN104490486A CN104490486A CN201410789315.9A CN201410789315A CN104490486A CN 104490486 A CN104490486 A CN 104490486A CN 201410789315 A CN201410789315 A CN 201410789315A CN 104490486 A CN104490486 A CN 104490486A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D1/00—Surgical instruments for veterinary use
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Abstract
The invention discloses a spring type animal beating device. The spring type animal beating device comprises a base, a fixator and an indication panel and beating parts, wherein the base is connected with the beating part through a screw, the indication panel is composed of a perpendicular panel and a slide panel, and the slide panel is additionally provided with a protractor and transversely slides on the perpendicular panel. The beating parts include a beating rod, a spring and a beating guide rail, and the beating rod moves along the beating guide rail. The invention provides a spring type animal beating method. The spring type small animal beating device can mark different beating forces with angle degrees, by replacing different springs and beating rods, beating of small and medium animals can be realized, injury classification animal beating models can be easily manufactured, and the spring type animal beating type is applicable to researches of biomechanics, injury mechanism and pathology.
Description
Technical field
The present invention relates to the biological percussion device of a kind of spring and method.
Background technology
Traumatic brain injury (traurnatic brain injury, TBI) be the common clinically emergency case of neurosurgery, also be one of major affliction threatening human life now, especially heavy head-brain injury mortality is very high, at about 30%-50%, in clinical studies, in order to genesis mechanism and the damage rear secondary disease reason physiological change illustrating TBI, improve early diagnostic rate, rationally effective remedy measures and rehabilitation maneuver is taked to reduce TBI mortality rate, to set up one and be of great significance with the machine-processed similar experimental animal model tool of clinical TBI.Since the forties, people apply multiple method and replicate and close platform TBI animal model, by its injure manner and machine-processed difference, be broadly divided into falling bodies impingement method, hydraulic punch striking, load of accelerating cause injury method, the contusion of controlling cortex etc., but the falling bodies percussion device existence scope of causing injury is difficult to control, damage is not easy fine quantization, is not suitable for the shortcoming of biomechanical analysis; Hydraulic pressure and load of accelerating device also have instrument complicated, and cost is high, it is loaded down with trivial details to operate, and is not easy the problems such as popularization.
Summary of the invention
For this reason, the present invention proposes the biological percussion device of a kind of new spring at least partially that can solve the problem and method.
According to an aspect of the present invention, provide the biological percussion device of a kind of spring, comprising: pedestal, holder, indication panel and hitting part, wherein, described pedestal is connected with described hitting part by screw; Described holder is fixedly connected with described pedestal; Described indication panel is made up of vertical panel and slidable panels, additional amount hornwork on described slidable panels, and described slidable panels laterally moves on described vertical panel; Described hitting part comprises hits rod, spring and strike guide rail, and one end of described spring is connected with described pedestal by the screw of plastic sheath, and described strike rod is connected with the other end of described spring, and described strike rod is along described strike guide rail movement.
Alternatively, according to the biological percussion device of spring of the present invention, after described holder is bent by rod iron, insert in the hole that described pedestal bores, formed so that nut is fixing.
Alternatively, according to the biological percussion device of spring of the present invention, described strike guide rail bends to semicircular rod iron by two to form, and the end points of described rod iron is fixed on described pedestal.
Alternatively, according to the biological percussion device of spring of the present invention, described holder comprises head and neck holder and extremity holder.
Alternatively, according to the biological percussion device of spring of the present invention, described pedestal corner is provided with leg.
Alternatively, according to the biological percussion device of spring of the present invention, described leg is made up of the screw with rubber sleeve.
Alternatively, according to the biological percussion device of spring of the present invention, the material of described strike rod is steel, ferrum or aluminum.
According to another aspect of the present invention, provide the biological striking method of a kind of spring, comprise the steps: S100, experimental subject is fixed on pedestal by head and neck holder and extremity holder;
S200, pulls described strike rod along strike guide rail;
S300, Spontaneous release hits rod, hits rod and to fall down to cause injury rapidly under the pulling force and action of gravity of spring experimental subject.
Alternatively, according to the biological striking method of spring of the present invention, in described step S200, record out the angle of described strike rod rotation and the length of described spring, the hitting dynamics that corresponding described strike rod is different.
Different hitting dynamics can indicate by use angle by the biological percussion device of spring of the present invention, by changing different springs and hitting rod, the strike of centering toy can be realized, make such Animal Wounds model quickly and easily, produce injury scale easily and hit animal model, be suitable for biomechanics, mechanism of injury, pathological research.
Accompanying drawing explanation
By reading hereafter detailed description of the preferred embodiment, various other advantage and benefit will become cheer and bright for those of ordinary skill in the art.Accompanying drawing only for illustrating the object of preferred implementation, and does not think limitation of the present invention.And in whole accompanying drawing, represent identical parts by identical reference marks.Wherein in the accompanying drawings, the multiple identical parts of alphabetic flag instruction after reference number, when making a general reference these parts, by its last alphabetic flag of omission.In the accompanying drawings:
Fig. 1 is the structural representation of the biological percussion device of spring of the present invention;
Fig. 2 is the flow chart of the biological striking method of spring of the present invention.
Wherein, in accompanying drawing, the implication of each labelling is:
Pedestal 1, indication panel 2, vertical panel 2-1, slidable panels 2-2, strike guide rail 3, strike rod 4, spring 5, head and neck holder 6-1, extremity holder 6-2, leg 7 and protractor 8.
Detailed description of the invention
Below in conjunction with accompanying drawing and concrete embodiment, the invention will be further described.
Fig. 1 shows the structural representation of the biological percussion device of spring of the present invention.As shown in Figure 1, the biological percussion device of described spring comprises pedestal 1, holder, indication panel 2 and hitting part, and wherein, described pedestal 1 plays fixing effect, described pedestal 1 is connected with described hitting part by screw, and described hitting part is for hitting experimental subject; Described holder is fixedly connected with described pedestal 1, and the mode be fixedly connected with has multiple, as riveted joint, welding, after described holder is bent by rod iron in the present invention, insert in the hole that described pedestal 1 bores, formed so that nut is fixing, described holder is used for fixing experimental subject; Described indication panel 2 is made up of vertical panel 2-1 and slidable panels 2-2, additional amount hornwork 8 on described slidable panels 2-2, and described slidable panels 2-2 laterally moves on described vertical panel 2-1, and described protractor 8 is for reading the number of degrees hitting rod 4 and rotate; Described hitting part comprises hits rod 4, spring 5 and hits guide rail 3, one end of described spring 5 is connected with described pedestal 1 by the screw of plastic sheath, described strike rod 4 is connected with the other end of described spring 5, and described strike rod 4 moves along described strike guide rail 3.
When using described spring biology percussion device, experimental subject is fixed on described pedestal 1 by described holder, then the protractor 8 moved on described slidable panels 2-2 is corresponding with the radian of described strike guide rail 3 to facilitate the reading number of degrees, pull described strike rod 4, described strike rod 4 is connected with described spring 5, described strike rod 4 moves on described strike guide rail 3 around the end points of described spring 5, the angle of described strike rod 4 rotation is read by described protractor 8, then rod 4 is hit described in Spontaneous release, described strike rod 4 falls down to cause injury rapidly experimental subject under the pulling force of described spring 5 and the action of gravity of described strike rod 4, then the experimental subject of causing injury is studied.
In the biological percussion device of spring of the present invention, described strike guide rail 3 bends to semicircular rod iron by two to form, and the end points of described rod iron is fixed on described pedestal 1.As shown in Figure 1, described strike guide rail 3 is fixedly connected on described pedestal 1, and the mode be fixedly connected with has multiple, and can be welding, also can rivet, also can be fixed by nut, the mode be fixedly connected with in the present invention be for fix by nut.The material of described strike guide rail 3 can be ferrum, aluminum or steel, and preferred material is steel.
In the biological percussion device of spring of the present invention, described holder comprises head and neck holder 6-1 and extremity holder 6-2.As shown in Figure 1, described holder comprises head and neck holder 6-1 and extremity holder 6-2, described head and neck holder 6-1 and described extremity holder 6-2 is fixed on described pedestal 1, described head and neck holder 6-1 is used for the head and neck of fixing experimental subject, and described extremity holder 6-2 is used for the extremity of fixing experimental subject.
In the biological percussion device of spring of the present invention, described pedestal 1 four jiaos is provided with leg 7, and described leg 7 is made up of the screw of band rubber sleeve.As shown in Figure 1, described pedestal 1 four jiaos is provided with leg 7, described leg 7 is made up of the screw of band rubber sleeve, and described leg 7 is for supporting fixing described pedestal 1.
In the biological percussion device of spring of the present invention, the material of described strike rod 4 is steel, ferrum or aluminum.Aluminum is argenteous light metal, has good ductility, can form the oxide-film that one deck prevents metal erosion in humid air.Ferrum is glossiness silvery white metal, and firmly have ductility, fusing point is 1535 DEG C, boiling point 2750 DEG C, has very strong ferromagnetism, and has good plasticity and heat conductivity.Steel take ferrum as essential element, and the metal material of carbon content generally also containing other elements below 2.0%, steel has better physics, chemistry, mechanical performance than the initial pig iron.The preferred material of described strike rod 4 is steel.
Present invention also offers the biological striking method of a kind of spring, as shown in Figure 2, comprise the steps:
S100, is fixed on pedestal 1 experimental subject by head and neck holder 6-1 and extremity holder 6-2;
S200, pulls along strike guide rail 3 and hits rod 4;
S300, Spontaneous release hits rod 4, hits rod 4 and to fall down to cause injury rapidly under the pulling force and action of gravity of spring 5 experimental subject.
In the biological striking method of spring of the present invention, in described step S200, record out the angle of described strike rod 4 rotation and the length of described spring 5, the hitting dynamics that corresponding described strike rod 4 is different.The angle of being rotated by described strike rod 4 and the length of described spring 5 can cause experimental subject wound in various degree, can reach experimental design requirement.
Be the Effect disquisition that experimental subject carries out the biological striking method of spring below by adult SD rats:
Animal and grouping: adult SD rats totally 70, male and female half and half, average weight 300 grams, is divided into 7 subgroups according to described spring 5 different length of the biological percussion device of spring and described strike rod 4 rotational angle.A group, 2cm, 180 °; B group, 2cm, 120 °; C group, 2cm, 90 °; D group, 3cm, 180 °; E group, 3cm, 120 °; F group, 3cm, 90 ° and matched group, often organize 10 animals.
Caused injury: be positioned on described pedestal 1 prostrate for the adult SD rats after suction etherization, incidence is fixed in described head and neck holder 6-1, and extremity are fixed in described extremity holder 6-2, pads a thick foam pad below.Described strike rod 4 is pulled to along described spring 5 fixing point and presets angle, Spontaneous release, and described strike rod 4 to fall down to cause injury adult SD rats along described strike guide rail 3 rapidly under the effect of described spring 5 pulling force.Hit the center line that position is rat eyes and ears line, after Animal Wounds, remove from the biological percussion device of spring rapidly, in order to avoid secondary wounds, do not apply recovery means, react after observing animal injury, be left intact after Normal group anesthesia.
Early stage neural reflex inspection: after adult SD rats is caused injury, remove from the biological percussion device of spring immediately, do not apply recovery means, show after observing adult SD rats damage, to between adult SD rats lucid interval after causing injury, observe corneal reflex, limb bounces back, pain stimulation hind leg flexion reflex suppresses the time, spontaneous local motion, and righting response (can roll when back is placed on the bottom of cage, but can not stand) time of occurrence, occur with righting response, the Judging index terminated as stupor of creeping voluntarily, record stupor time.
Mortality rate calculates: after adult SD rats recovers autonomic activities, steams again and raises, and after damage, 24h records death toll, calculates mortality rate.
Sample process: all dead adult SD rats open breast at once, after 40g/L paraformaldehyde carefully pours into fixing 10mi n, broken end gets brain, fixes 24h (4 DEG C) after being placed in 40g/L paraformaldehyde, conventional dehydration, paraffin embedding.In strike position row coronalplane serial section, thickness is about 10um, and HE dyes.Process as stated above after not dead adult SD rats 24h.
Result: the rear early stage neural reflex of (1) damage: matched group reactivated mostly in 15 seconds, F group is average goes into a coma 25 seconds, and C group extends a little approximately goes into a coma 5 minutes, and E group is on average gone into a coma 30 minutes, the average stupor of B group 4 hours, the average stupor of D group 8 hours.(2) craniocerebral injury mortality rate: after 24 hours, A group is all dead, and B group 50% is dead, and C group 10% is dead, and D group 80% is dead, and E group 20% is dead, and F group is without dead.A group, D group are dead to be occurred after injury in 10 minutes mostly, and the cause of death is respiration inhibition.
Brain HE stained tissue pathological examination: A group, the visible fracture of skull of D group, diffusivity subarachnoid hemorrhage, all the other each group has no fracture of skull, diffusivity subarachnoid hemorrhage.Under mirror, the visible large area cortex of A group, D group is dampened, and scope is comparatively extensive, has no obvious change under F arrangement of mirrors.All the other respectively organize little contusion stove in visible limitation subarachnoid hemorrhage, partial rat Lu Gan and brain essence.Cortex, Hippocampus, thalamus, the performance of the neuronal damage that all visible weight of brain stem differs, and visible diffuse cerebral edema.
Conclusion: preliminary experiment shows, utilizes this device to test rat, can cause the wound in various degree of animal head, can reach experimental design requirement completely, have good operability and repeatability, is a kind of novel research device of causing injury.This device is except the damage research that can be used for brain, and also can be used for the local damage research of other position or organ, the small-sized percussion device of spring of visible development is comparatively ideal injury device, is expected to have larger application prospect.Different hitting dynamics can indicate by use angle by this device; By changing the spring of different length, hardness, and the steel rod of different thicknesses, can realize centering toy (as large old mouselet, rabbit, cat) etc. strike, make such Animal Wounds model quickly and easily, this modeling method is by many sections of papers quoteds, proof successfully can produce close copy, modeling economical.Can produce injury scale easily by this device and hit animal model, be suitable for biomechanics Research, mechanism of injury is studied, pathological research.
Different hitting dynamics can indicate by use angle by the biological percussion device of spring of the present invention, by changing different springs and hitting rod, the strike of centering toy can be realized, make such Animal Wounds model quickly and easily, produce injury scale easily and hit animal model, be suitable for biomechanics, mechanism of injury, pathological research.
It should be noted, the present invention will be described instead of limit the invention for above-described embodiment, and those skilled in the art can design alternative embodiment when not departing from the scope of claims.In the claims, any reference marks between bracket should be configured to limitations on claims.Word " comprises " not to be got rid of existence and does not arrange element in the claims or step.Word "a" or "an" before being positioned at element is not got rid of and be there is multiple such element.The present invention can by means of including the hardware of some different elements and realizing by means of the computer of suitably programming.In the unit claim listing some devices, several in these devices can be carry out imbody by same hardware branch.Word first, second and third-class use do not represent any order.Can be title by these word explanations.
Claims (9)
1. the biological percussion device of spring, is characterized in that comprising: pedestal (1), holder, indication panel (2) and hitting part, wherein,
Described pedestal (1) is connected with described hitting part by screw;
Described holder is fixedly connected with described pedestal (1);
Described indication panel (2) is made up of vertical panel (2-1) and slidable panels (2-2), the upper additional amount hornwork (8) of described slidable panels (2-2), described slidable panels (2-2) laterally moves on described vertical panel (2-1);
Described hitting part comprises hits rod (4), spring (5) and hits guide rail (3), one end of described spring (5) is connected with described pedestal (1) by the screw of plastic sheath, described strike rod (4) is connected with the other end of described spring (5), and described strike rod (4) is moved along described strike guide rail (3).
2. the biological percussion device of spring according to claim 1, is characterized in that: after described holder is bent by rod iron, inserts in the upper hole of boring of described pedestal (1), is formed so that nut is fixing.
3. the biological percussion device of spring according to claim 1, is characterized in that: described strike guide rail (3) bends to semicircular rod iron by two to form, and the end points of described rod iron is fixed on described pedestal (1).
4. the biological percussion device of spring according to claim 1, is characterized in that: described holder comprises head and neck holder (6-1) and extremity holder (6-2).
5. the biological percussion device of spring according to claim 1, is characterized in that: described pedestal (1) corner is provided with leg (7).
6. the biological percussion device of spring according to claim 5, is characterized in that: described leg (7) is made up of the screw of band rubber sleeve.
7. the biological percussion device of spring according to claim 1, is characterized in that: the material of described strike rod (4) is steel, ferrum or aluminum.
8. the biological striking method of spring, comprises the steps:
S100, is fixed on pedestal (1) experimental subject by head and neck holder (6-1) and extremity holder (6-2);
S200, pulls along strike guide rail (3) and hits rod (4);
S300, Spontaneous release hits rod (4), hits rod (4) and to fall down to cause injury rapidly under the pulling force and action of gravity of spring (5) experimental subject.
9. the biological percussion device of spring according to claim 8, it is characterized in that: in described step S200, record out the length of angle that described strike rod (4) rotates and described spring (5), the hitting dynamics that corresponding described strike rod (4) is different.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410789315.9A CN104490486A (en) | 2014-12-18 | 2014-12-18 | Spring type animal beating device and method |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410789315.9A CN104490486A (en) | 2014-12-18 | 2014-12-18 | Spring type animal beating device and method |
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| CN104490486A true CN104490486A (en) | 2015-04-08 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109717982A (en) * | 2019-03-15 | 2019-05-07 | 河南医学高等专科学校 | A kind of percussion device causing the damage of minitype animal experiment brainpan |
| CN113876459A (en) * | 2021-09-30 | 2022-01-04 | 中国人民解放军陆军特色医学中心 | Animal injury-causing device capable of autonomously controlling impact force |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201930095U (en) * | 2011-01-17 | 2011-08-17 | 上海长征医院 | Impingement device |
| CN103263306A (en) * | 2013-04-23 | 2013-08-28 | 中国人民解放军成都军区总医院 | Device for modeling craniocerebral impact injuries of small animals |
| CN203576679U (en) * | 2013-11-08 | 2014-05-07 | 中国人民解放军成都军区总医院 | Biological impact machine for small rodents |
-
2014
- 2014-12-18 CN CN201410789315.9A patent/CN104490486A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN201930095U (en) * | 2011-01-17 | 2011-08-17 | 上海长征医院 | Impingement device |
| CN103263306A (en) * | 2013-04-23 | 2013-08-28 | 中国人民解放军成都军区总医院 | Device for modeling craniocerebral impact injuries of small animals |
| CN203576679U (en) * | 2013-11-08 | 2014-05-07 | 中国人民解放军成都军区总医院 | Biological impact machine for small rodents |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109717982A (en) * | 2019-03-15 | 2019-05-07 | 河南医学高等专科学校 | A kind of percussion device causing the damage of minitype animal experiment brainpan |
| CN109717982B (en) * | 2019-03-15 | 2020-07-24 | 河南医学高等专科学校 | Striking device for causing brain injury of small experimental animal |
| CN113876459A (en) * | 2021-09-30 | 2022-01-04 | 中国人民解放军陆军特色医学中心 | Animal injury-causing device capable of autonomously controlling impact force |
| CN113876459B (en) * | 2021-09-30 | 2023-11-07 | 中国人民解放军陆军特色医学中心 | Animal injury device capable of automatically controlling impact force |
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Application publication date: 20150408 |