CN104474475A - Traditional Chinese medicine for treating colorectal cancer caused by spleen deficiency and dampness-heat - Google Patents

Traditional Chinese medicine for treating colorectal cancer caused by spleen deficiency and dampness-heat Download PDF

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Publication number
CN104474475A
CN104474475A CN201410743429.XA CN201410743429A CN104474475A CN 104474475 A CN104474475 A CN 104474475A CN 201410743429 A CN201410743429 A CN 201410743429A CN 104474475 A CN104474475 A CN 104474475A
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parts
radix
grams
herba
rhizoma
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李玉富
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Abstract

The invention discloses a traditional Chinese medicine for treating colorectal cancer caused by spleen deficiency and dampness-heat. The traditional Chinese medicine is prepared from the following medicinal materials: radix sophorae flavescentis, radix codonopsis, ginseng, herba agrimoniae, garden balsam seeds, rhizoma atractylodis macrocephalae, rhizoma atractylodis, magnolia officinalis, Chinese brake herbs, humifuse euphorbia herbs, dahurian patrinia herbs, hedyotis diffusa, Chinese pulsatilla roots, sculellaria barbata, nightshade, radix linderae, bittersweet herbs, semen coicis, radix paeoniae alba, wild grape roots, bitter oranges, Indian strawberries, sargentgloryvine stems, radix paeoniae rubra, ground beetles, alpine yarrow herbs, selaginella doederleinii, cephalotaxus fortunei, terfezia leonis, astragalus, tuckahoe, angelica sinensis, suberect spatholobus stems, radix rehmanniae praeparata, fomes fomentarius, tortoise plastron, radix aconiti lateralis preparata, sweet potatoes, morinda officinalis, cinnamon, herba epimedii, actinidia arguta, semen cuscutae, rhizoma corydalis, szechwan chinaberry fruits, olibanum, rhizoma alismatis, polyporus umbellatus, peach kernels, salvia miltiorrhiza, spina gleditsiae, glossy privet fruits, rhizoma sparganii, curcuma zedoary, raw semen coicis, rhizoma smilacis glabrae, eclipta alba and paris polyphylla. Clinical experiments prove that the traditional Chinese medicine can be used for safely and effectively treating colorectal cancer caused by spleen deficiency and dampness-heat.

Description

A kind of Chinese medicine for the treatment of insufficiency of the spleen damp-heat type colorectal cancer
Technical field
The present invention relates to a kind of Chinese medicine, particularly a kind of Chinese medicine for the treatment of insufficiency of the spleen damp-heat type colorectal cancer.
Background technology
The morbidity of colorectal cancer is a complicated process, or first has insufficiency of the spleen, rear raw excess pathogen, or first has heresy to invade, and taste are killd, insufficiency of the spleen always one of them important pathological factor.The spleen being the foundation of acquired constitution, main transporting, insufficiency of the spleen then dysfunction of the spleen in transportation and transformation, precise and tiny mistake cloth, water is wet to stop storing, solidifying and do not fall apart, and accumulate in the course of time and make poison, wet, expectorant, poison, the stasis of blood are tied mutually, accumulate resistance intestinal internal organs, are substantial pathogenic factor, send out as primary disease.Thus insufficiency of the spleen close with the generation development relationship of colorectal cancer, Ming Dynasty's Zhang Jingyue is said: " people of spleen kidney deficiency and debilitating disorder has the disease gathered more." surfeit is rich, pure wine savoury, impairing the spleen and stomach, transporting mistake department, causes endogenous dampness, pents up into expectorant, accumulates in the course of time and makes poison, multiple abscess large intestine; Endogenous cause of ill disorder of emotion, the stagnation of QI network stasis of blood, ties mutually with noxious dampness, and contamination intestinal, forms tumor.Therefore, detoxification and promoting urination, blood circulation promoting and blood stasis dispelling are the important method for the treatment of of primary disease.Invigorating the spleen and benefiting QI medicine is improved the effect of immune function of human body and natural repair ability, is conducive to the growth of Tumor suppression, improves the body constitution of patient, promotes rehabilitation, extends life cycle.
Summary of the invention
The problem to be solved in the present invention is: provide a kind of Chinese medicine for the treatment of insufficiency of the spleen damp-heat type colorectal cancer, by selecting suitable medical material and proportioning thereof, reaches the object of the insufficiency of the spleen damp-heat type colorectal cancer of safe and effective healing.
In order to solve the problems of the technologies described above, the present invention by the following technical solutions:
Treat a Chinese medicine for insufficiency of the spleen damp-heat type colorectal cancer, it is characterized in that, it is prepared into by the medical material of following parts by weight proportioning: Radix Sophorae Flavescentis 20 parts, Radix Codonopsis 15 parts, Radix Ginseng 12 parts, Herba Agrimoniae 12 parts, Semen Impatientis 15 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Rhizoma Atractylodis 12 parts, Cortex Magnoliae Officinalis 12 parts, Herba Pteridis Multifidae 20 parts, Herba Euphorbiae Humifusae 25 parts, Herba Patriniae 50 parts, Herba Hedyotidis Diffusae 50 parts, the Radix Pulsatillae 20 parts, Herba Scutellariae Barbatae 30 parts, Herba Solani Nigri 20 parts, the Radix Linderae 12 parts, Herba Solani Lyrati 12 parts, Semen Coicis 25 parts, the Radix Paeoniae Alba 12 parts, Radix vitis romanetii 25 parts, Fructus Aurantii 12 parts, Herba Duchesneae Indicae 25 parts, Caulis Sargentodoxae 20 parts, Radix Paeoniae Rubra 12 parts, Eupolyphaga Seu Steleophaga 15 parts, achillea millefolium 12 parts, Herba Selaginellae Doederleinii 12 parts, Folium et Ramulus Cephalotaxi 12 parts, 12 parts, the mushroom in tumor spore ground, the Radix Astragali 12 parts, 12 parts, Poria, Radix Angelicae Sinensis 12 parts, Caulis Spatholobi 15 parts, 12 parts, Radix Rehmanniae Preparata, Fomes Fomentarius 12 parts, Carapax et Plastrum Testudinis 12 parts, Radix Aconiti Lateralis Preparata 6 parts, 12 parts, Ipomoea batatas Lam., Radix Morindae Officinalis 12 parts, Cortex Cinnamomi 9 parts, Herba Epimedii 12 parts, Fructus Actinidiae Argutae 12 parts, Semen Cuscutae 12 parts, Rhizoma Corydalis 15 parts, Fructus Toosendan 15 parts, Olibanum 12 parts, Rhizoma Alismatis 10 parts, Polyporus 12 parts, 12 parts, Semen Persicae, Radix Salviae Miltiorrhizae 15 parts, Spina Gleditsiae 12 parts, Fructus Ligustri Lucidi 15 parts, Rhizoma Sparganii 12 parts, Rhizoma Curcumae 12 parts, Semen Coicis 15 parts, Rhizoma Smilacis Glabrae 12 parts, Herba Ecliptae 12 parts, Rhizoma Paridis 15 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, general material
Inventor collects the out-patient of 60 routine insufficiency of the spleen damp-heat type colorectal cancer altogether between in February ,-2014 in January calendar year 2001, age 40-70 year.Be divided at random: treatment group 40 example, matched group 20 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2, test method
Matched group oral anti-cancer medicine, sooner or later respectively once.6 months courses for the treatment of.
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 1, every bu is taken for 2 times sooner or later.6 months courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
(1) fully recover: clinical symptoms and sign disappear completely or substantially disappear;
(2) effective: clinical symptoms and sign major part take a turn for the better or be clearly better;
(3) invalid; Clinical symptoms and sign are all not improved, symptom as front, DeGrain.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
Group Case number Recovery from illness Effective Invalid Untoward reaction Total effective rate %
Treatment group 40 34 4 2 0(0％) 95％
Matched group 20 0 1 19 0(0％) 5％
Visible, the medicine that the preferred embodiment for the present invention obtains can treat insufficiency of the spleen damp-heat type colorectal cancer safely and effectively.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take Radix Sophorae Flavescentis 20 grams, Radix Codonopsis 15 grams, Radix Ginseng 12 grams, Herba Agrimoniae 12 grams, Semen Impatientis 15 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Rhizoma Atractylodis 12 grams, Cortex Magnoliae Officinalis 12 grams, Herba Pteridis Multifidae 20 grams, Herba Euphorbiae Humifusae 25 grams, Herba Patriniae 50 grams, Herba Hedyotidis Diffusae 50 grams, the Radix Pulsatillae 20 grams, Herba Scutellariae Barbatae 30 grams, Herba Solani Nigri 20 grams, the Radix Linderae 12 grams, Herba Solani Lyrati 12 grams, Semen Coicis 25 grams, the Radix Paeoniae Alba 12 grams, Radix vitis romanetii 25 grams, Fructus Aurantii 12 grams, Herba Duchesneae Indicae 25 grams, Caulis Sargentodoxae 20 grams, Radix Paeoniae Rubra 12 grams, Eupolyphaga Seu Steleophaga 15 grams, achillea millefolium 12 grams, Herba Selaginellae Doederleinii 12 grams, Folium et Ramulus Cephalotaxi 12 grams, 12 grams, the mushroom in tumor spore ground, the Radix Astragali 12 grams, 12 grams, Poria, Radix Angelicae Sinensis 12 grams, Caulis Spatholobi 15 grams, 12 grams, Radix Rehmanniae Preparata, Fomes Fomentarius 12 grams, Carapax et Plastrum Testudinis 12 grams, Radix Aconiti Lateralis Preparata 6 grams, 12 grams, Ipomoea batatas Lam., Radix Morindae Officinalis 12 grams, Cortex Cinnamomi 9 grams, Herba Epimedii 12 grams, Fructus Actinidiae Argutae 12 grams, Semen Cuscutae 12 grams, Rhizoma Corydalis 15 grams, Fructus Toosendan 15 grams, Olibanum 12 grams, Rhizoma Alismatis 10 grams, Polyporus 12 grams, 12 grams, Semen Persicae, Radix Salviae Miltiorrhizae 15 grams, Spina Gleditsiae 12 grams, Fructus Ligustri Lucidi 15 grams, Rhizoma Sparganii 12 grams, Rhizoma Curcumae 12 grams, Semen Coicis 15 grams, Rhizoma Smilacis Glabrae 12 grams, Herba Ecliptae 12 grams, Rhizoma Paridis 15 grams.Add 10 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, load in capsulae vacuus, the capsule of adult normal's one day consumption must be met.
Be used for the treatment of insufficiency of the spleen damp-heat type colorectal cancer.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take Radix Sophorae Flavescentis 20 grams, Radix Codonopsis 15 grams, Radix Ginseng 12 grams, Herba Agrimoniae 12 grams, Semen Impatientis 15 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Rhizoma Atractylodis 12 grams, Cortex Magnoliae Officinalis 12 grams, Herba Pteridis Multifidae 20 grams, Herba Euphorbiae Humifusae 25 grams, Herba Patriniae 50 grams, Herba Hedyotidis Diffusae 50 grams, the Radix Pulsatillae 20 grams, Herba Scutellariae Barbatae 30 grams, Herba Solani Nigri 20 grams, the Radix Linderae 12 grams, Herba Solani Lyrati 12 grams, Semen Coicis 25 grams, the Radix Paeoniae Alba 12 grams, Radix vitis romanetii 25 grams, Fructus Aurantii 12 grams, Herba Duchesneae Indicae 25 grams, Caulis Sargentodoxae 20 grams, Radix Paeoniae Rubra 12 grams, Eupolyphaga Seu Steleophaga 15 grams, achillea millefolium 12 grams, Herba Selaginellae Doederleinii 12 grams, Folium et Ramulus Cephalotaxi 12 grams, 12 grams, the mushroom in tumor spore ground, the Radix Astragali 12 grams, 12 grams, Poria, Radix Angelicae Sinensis 12 grams, Caulis Spatholobi 15 grams, 12 grams, Radix Rehmanniae Preparata, Fomes Fomentarius 12 grams, Carapax et Plastrum Testudinis 12 grams, Radix Aconiti Lateralis Preparata 6 grams, 12 grams, Ipomoea batatas Lam., Radix Morindae Officinalis 12 grams, Cortex Cinnamomi 9 grams, Herba Epimedii 12 grams, Fructus Actinidiae Argutae 12 grams, Semen Cuscutae 12 grams, Rhizoma Corydalis 15 grams, Fructus Toosendan 15 grams, Olibanum 12 grams, Rhizoma Alismatis 10 grams, Polyporus 12 grams, 12 grams, Semen Persicae, Radix Salviae Miltiorrhizae 15 grams, Spina Gleditsiae 12 grams, Fructus Ligustri Lucidi 15 grams, Rhizoma Sparganii 12 grams, Rhizoma Curcumae 12 grams, Semen Coicis 15 grams, Rhizoma Smilacis Glabrae 12 grams, Herba Ecliptae 12 grams, Rhizoma Paridis 15 grams.Add 12 times of water gagings, decoct 2 hours, filter; Filtering residue adds 10 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of insufficiency of the spleen damp-heat type colorectal cancer.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take Radix Sophorae Flavescentis 20 grams, Radix Codonopsis 15 grams, Radix Ginseng 12 grams, Herba Agrimoniae 12 grams, Semen Impatientis 15 grams, the Rhizoma Atractylodis Macrocephalae 12 grams, Rhizoma Atractylodis 12 grams, Cortex Magnoliae Officinalis 12 grams, Herba Pteridis Multifidae 20 grams, Herba Euphorbiae Humifusae 25 grams, Herba Patriniae 50 grams, Herba Hedyotidis Diffusae 50 grams, the Radix Pulsatillae 20 grams, Herba Scutellariae Barbatae 30 grams, Herba Solani Nigri 20 grams, the Radix Linderae 12 grams, Herba Solani Lyrati 12 grams, Semen Coicis 25 grams, the Radix Paeoniae Alba 12 grams, Radix vitis romanetii 25 grams, Fructus Aurantii 12 grams, Herba Duchesneae Indicae 25 grams, Caulis Sargentodoxae 20 grams, Radix Paeoniae Rubra 12 grams, Eupolyphaga Seu Steleophaga 15 grams, achillea millefolium 12 grams, Herba Selaginellae Doederleinii 12 grams, Folium et Ramulus Cephalotaxi 12 grams, 12 grams, the mushroom in tumor spore ground, the Radix Astragali 12 grams, 12 grams, Poria, Radix Angelicae Sinensis 12 grams, Caulis Spatholobi 15 grams, 12 grams, Radix Rehmanniae Preparata, Fomes Fomentarius 12 grams, Carapax et Plastrum Testudinis 12 grams, Radix Aconiti Lateralis Preparata 6 grams, 12 grams, Ipomoea batatas Lam., Radix Morindae Officinalis 12 grams, Cortex Cinnamomi 9 grams, Herba Epimedii 12 grams, Fructus Actinidiae Argutae 12 grams, Semen Cuscutae 12 grams, Rhizoma Corydalis 15 grams, Fructus Toosendan 15 grams, Olibanum 12 grams, Rhizoma Alismatis 10 grams, Polyporus 12 grams, 12 grams, Semen Persicae, Radix Salviae Miltiorrhizae 15 grams, Spina Gleditsiae 12 grams, Fructus Ligustri Lucidi 15 grams, Rhizoma Sparganii 12 grams, Rhizoma Curcumae 12 grams, Semen Coicis 15 grams, Rhizoma Smilacis Glabrae 12 grams, Herba Ecliptae 12 grams, Rhizoma Paridis 15 grams.Add 8 times of water gagings, decoct 2 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, must meet the granule of adult normal's one day consumption.
Be used for the treatment of insufficiency of the spleen damp-heat type colorectal cancer.Oral, every bu is taken for twice sooner or later.
Facts have proved through a large amount of clinical treatments, the present invention treats the Chinese medicine of insufficiency of the spleen damp-heat type colorectal cancer, belongs to pure Chinese medicinal preparation, little to human body toxicity, side effect, and to treating, insufficiency of the spleen damp-heat type colorectal cancer has reliably, safety, significant therapeutic effect.

Claims (1)

1. treat a Chinese medicine for insufficiency of the spleen damp-heat type colorectal cancer, it is characterized in that, it is prepared into by the medical material of following parts by weight proportioning: Radix Sophorae Flavescentis 20 parts, Radix Codonopsis 15 parts, Radix Ginseng 12 parts, Herba Agrimoniae 12 parts, Semen Impatientis 15 parts, the Rhizoma Atractylodis Macrocephalae 12 parts, Rhizoma Atractylodis 12 parts, Cortex Magnoliae Officinalis 12 parts, Herba Pteridis Multifidae 20 parts, Herba Euphorbiae Humifusae 25 parts, Herba Patriniae 50 parts, Herba Hedyotidis Diffusae 50 parts, the Radix Pulsatillae 20 parts, Herba Scutellariae Barbatae 30 parts, Herba Solani Nigri 20 parts, the Radix Linderae 12 parts, Herba Solani Lyrati 12 parts, Semen Coicis 25 parts, the Radix Paeoniae Alba 12 parts, Radix vitis romanetii 25 parts, Fructus Aurantii 12 parts, Herba Duchesneae Indicae 25 parts, Caulis Sargentodoxae 20 parts, Radix Paeoniae Rubra 12 parts, Eupolyphaga Seu Steleophaga 15 parts, achillea millefolium 12 parts, Herba Selaginellae Doederleinii 12 parts, Folium et Ramulus Cephalotaxi 12 parts, 12 parts, the mushroom in tumor spore ground, the Radix Astragali 12 parts, 12 parts, Poria, Radix Angelicae Sinensis 12 parts, Caulis Spatholobi 15 parts, 12 parts, Radix Rehmanniae Preparata, Fomes Fomentarius 12 parts, Carapax et Plastrum Testudinis 12 parts, Radix Aconiti Lateralis Preparata 6 parts, 12 parts, Ipomoea batatas Lam., Radix Morindae Officinalis 12 parts, Cortex Cinnamomi 9 parts, Herba Epimedii 12 parts, Fructus Actinidiae Argutae 12 parts, Semen Cuscutae 12 parts, Rhizoma Corydalis 15 parts, Fructus Toosendan 15 parts, Olibanum 12 parts, Rhizoma Alismatis 10 parts, Polyporus 12 parts, 12 parts, Semen Persicae, Radix Salviae Miltiorrhizae 15 parts, Spina Gleditsiae 12 parts, Fructus Ligustri Lucidi 15 parts, Rhizoma Sparganii 12 parts, Rhizoma Curcumae 12 parts, Semen Coicis 15 parts, Rhizoma Smilacis Glabrae 12 parts, Herba Ecliptae 12 parts, Rhizoma Paridis 15 parts.
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