CN104436140B - Treat the medicine of beriberi cardiopathy - Google Patents
Treat the medicine of beriberi cardiopathy Download PDFInfo
- Publication number
- CN104436140B CN104436140B CN201410780891.7A CN201410780891A CN104436140B CN 104436140 B CN104436140 B CN 104436140B CN 201410780891 A CN201410780891 A CN 201410780891A CN 104436140 B CN104436140 B CN 104436140B
- Authority
- CN
- China
- Prior art keywords
- parts
- root
- tuber
- medicine
- radix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 27
- 206010047601 Vitamin B1 deficiency Diseases 0.000 title claims abstract description 17
- 208000002894 beriberi Diseases 0.000 title claims abstract description 17
- 235000006886 Zingiber officinale Nutrition 0.000 claims abstract description 14
- 235000008397 ginger Nutrition 0.000 claims abstract description 14
- 241000427159 Achyranthes Species 0.000 claims abstract description 13
- 241000132012 Atractylodes Species 0.000 claims abstract description 13
- 241000282817 Bovidae Species 0.000 claims abstract description 13
- 244000037364 Cinnamomum aromaticum Species 0.000 claims abstract description 13
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims abstract description 13
- 244000303040 Glycyrrhiza glabra Species 0.000 claims abstract description 13
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 13
- 235000017443 Hedysarum boreale Nutrition 0.000 claims abstract description 13
- 235000007858 Hedysarum occidentale Nutrition 0.000 claims abstract description 13
- 239000009636 Huang Qi Substances 0.000 claims abstract description 13
- 240000002948 Ophiopogon intermedius Species 0.000 claims abstract description 13
- 241001522129 Pinellia Species 0.000 claims abstract description 13
- 241000405414 Rehmannia Species 0.000 claims abstract description 13
- 240000007164 Salvia officinalis Species 0.000 claims abstract description 13
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 claims abstract description 13
- 235000005412 red sage Nutrition 0.000 claims abstract description 13
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 11
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 11
- 241001078983 Tetradium ruticarpum Species 0.000 claims abstract description 9
- 244000273928 Zingiber officinale Species 0.000 claims abstract description 6
- 244000126002 Ziziphus vulgaris Species 0.000 claims abstract description 6
- 239000011691 vitamin B1 Substances 0.000 abstract description 12
- 235000010374 vitamin B1 Nutrition 0.000 abstract description 12
- 229930003451 Vitamin B1 Natural products 0.000 abstract description 10
- 229960003495 thiamine Drugs 0.000 abstract description 10
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 abstract description 10
- 238000000034 method Methods 0.000 abstract description 3
- 241000411851 herbal medicine Species 0.000 abstract description 2
- 238000001802 infusion Methods 0.000 abstract description 2
- 230000008092 positive effect Effects 0.000 abstract description 2
- 229940126532 prescription medicine Drugs 0.000 abstract description 2
- 230000000694 effects Effects 0.000 description 23
- 239000000796 flavoring agent Substances 0.000 description 14
- 235000019634 flavors Nutrition 0.000 description 14
- 210000004185 liver Anatomy 0.000 description 14
- 210000004072 lung Anatomy 0.000 description 13
- 210000000952 spleen Anatomy 0.000 description 13
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 12
- 210000002784 stomach Anatomy 0.000 description 12
- 239000008280 blood Substances 0.000 description 11
- 210000004369 blood Anatomy 0.000 description 11
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 10
- 206010047700 Vomiting Diseases 0.000 description 10
- 235000009508 confectionery Nutrition 0.000 description 10
- 241000234314 Zingiber Species 0.000 description 8
- 241001247821 Ziziphus Species 0.000 description 8
- 230000001737 promoting effect Effects 0.000 description 8
- 206010030124 Oedema peripheral Diseases 0.000 description 7
- 206010038743 Restlessness Diseases 0.000 description 6
- 239000002253 acid Substances 0.000 description 6
- 238000003745 diagnosis Methods 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 210000002216 heart Anatomy 0.000 description 6
- 210000003734 kidney Anatomy 0.000 description 6
- 235000014655 lactic acid Nutrition 0.000 description 6
- 239000004310 lactic acid Substances 0.000 description 6
- 206010011703 Cyanosis Diseases 0.000 description 5
- 230000036772 blood pressure Effects 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 230000035485 pulse pressure Effects 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 206010019842 Hepatomegaly Diseases 0.000 description 4
- 206010062717 Increased upper airway secretion Diseases 0.000 description 4
- 208000002151 Pleural effusion Diseases 0.000 description 4
- 208000004880 Polyuria Diseases 0.000 description 4
- LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 description 4
- 208000006673 asthma Diseases 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 210000003414 extremity Anatomy 0.000 description 4
- 230000001939 inductive effect Effects 0.000 description 4
- 238000009527 percussion Methods 0.000 description 4
- 208000026435 phlegm Diseases 0.000 description 4
- 210000003462 vein Anatomy 0.000 description 4
- 206010011224 Cough Diseases 0.000 description 3
- 206010030302 Oliguria Diseases 0.000 description 3
- 208000001431 Psychomotor Agitation Diseases 0.000 description 3
- 230000002411 adverse Effects 0.000 description 3
- 210000001367 artery Anatomy 0.000 description 3
- 210000000988 bone and bone Anatomy 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 210000004243 sweat Anatomy 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 206010030113 Oedema Diseases 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 210000001124 body fluid Anatomy 0.000 description 2
- 239000010839 body fluid Substances 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 206010016256 fatigue Diseases 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 208000019622 heart disease Diseases 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 230000003119 painkilling effect Effects 0.000 description 2
- 238000005498 polishing Methods 0.000 description 2
- 229940107700 pyruvic acid Drugs 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000005728 strengthening Methods 0.000 description 2
- 201000004647 tinea pedis Diseases 0.000 description 2
- 230000017423 tissue regeneration Effects 0.000 description 2
- 235000017166 Bambusa arundinacea Nutrition 0.000 description 1
- 235000017491 Bambusa tulda Nutrition 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 241000521257 Hydrops Species 0.000 description 1
- 206010025476 Malabsorption Diseases 0.000 description 1
- 208000004155 Malabsorption Syndromes Diseases 0.000 description 1
- 206010029458 Nodal arrhythmia Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 244000082204 Phyllostachys viridis Species 0.000 description 1
- 235000015334 Phyllostachys viridis Nutrition 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 208000031353 Systolic Murmurs Diseases 0.000 description 1
- 241001251949 Xanthium sibiricum Species 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 210000000683 abdominal cavity Anatomy 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 239000011425 bamboo Substances 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 208000017580 chronic wasting disease Diseases 0.000 description 1
- 239000005515 coenzyme Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 239000010977 jade Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 238000003359 percent control normalization Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000036581 peripheral resistance Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 206010037833 rales Diseases 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- BWMISRWJRUSYEX-SZKNIZGXSA-N terbinafine hydrochloride Chemical compound Cl.C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 BWMISRWJRUSYEX-SZKNIZGXSA-N 0.000 description 1
- 239000002341 toxic gas Substances 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/254—Acanthopanax or Eleutherococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/754—Evodia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The medicine for the treatment of beriberi cardiopathy belongs to medical domain, and in particular to a kind of prescription medicine for treating beriberi cardiopathy.The present invention includes following Chinese herbal medicine：Orange peel, the tuber of dwarf lilyturf, radix bupleuri, the bighead atractylodes rhizome, antelope's horn, evodia rutaecarpa, the tuber of pinellia, PORIA ALBA, the root of bidentate achyranthes, the dried rhizome of rehmannia, cassia twig, cortex acanthopanacis, the red sage root, the Radix Astragali, radix polygonati officinalis, honey-fried licorice root, ginger, jujube, it is characterised in that：Each Chinese medicine parts by weight are 10 15 parts of orange peel, 69 parts of the tuber of dwarf lilyturf, 58 parts of radix bupleuri, 8 12 parts of the bighead atractylodes rhizome, 8 12 parts of antelope's horn, evodia rutaecarpa, 10 15 parts, 15 20 parts of the tuber of pinellia, 5 10 parts of PORIA ALBA, 8 10 parts of the root of bidentate achyranthes, 12 15 parts of the dried rhizome of rehmannia, 58 parts of cassia twig, 69 parts of cortex acanthopanacis, 15 20 parts of the red sage root, 8 12 parts of the Radix Astragali, 10 15 parts of radix polygonati officinalis, 9 12 parts of honey-fried licorice root, 57 parts of ginger, 57 parts of jujube, above-mentioned Chinese medicine is according to Traditional medicine infusion method, vitamin B1 is taken in cooperation, for treating beriberi cardiopathy positive effect, effective percentage 100%, cure rate more than 98%.
Description
Technical field
The invention belongs to medical domain, and in particular to a kind of prescription medicine for treating beriberi cardiopathy.
Background technology
Beriberi cardiopathy is that vitamin B1 is serious and a kind of high discharge capacity type heart disease caused by lacking for a long time；This
Disease is that cyanosis on the face and lips is wandering, the athlete's foot that nausea and vomiting etc. are characterized with simultaneously had palpitation asthma.Pathogenesis, vitamin
B1 participates in the metabolic process of carbohydrate as a kind of coenzyme, and important catalytic action is played in intermediate supersession oxidizing process, lacks
Vitamin B1 can make pyruvic acid be difficult to enter the circulation of three shuttles acid and aoxidize, thus the concentration of pyruvic acid and its predecessor's lactic acid increases in blood
It is more, make arteriolar dilatation around, peripheral resistance lowers, therefore diastole drops, and pulse pressure increase, venous return increases, heart burden
Increase.
Tcm diagnosis is this disease by rheumatism poison gas, enters from pin interior, is mutually fought with visceral-qi, knot is poly- not to be dissipated, therefore abdominal distnetion is anxious
；Palpitaition asthma is shown as, cyanosis on the face and lips, edema of lower extremity, apathetic, limbs are heavy, and tongue nature is light fat, and white,slippery and moist fur, arteries and veins moistens.
The western medical treatment illness is independent replenishing vitamins B1, but due to lacking vitamin B1 in food merely at present
Caused ill situation it is seldom, occur illness more be due to constitution difference, intestines and stomach malabsorption or chronic wasting disease
The medicine of caused beriberi cardiopathy, simple replenishing vitamins B1 cure the symptoms, not the disease.
The content of the invention
To solve problem above, the present invention provides a kind of medicine for the treatment beriberi cardiopathy that can treat both principal and secondary aspect of disease.
Treatment by Chinese herbs beriberi cardiopathy drops turbid, stopping nausea and vomiting by lowering the adverse flow of QI with dampness elimination, and dissolving lump and resolving mass is promoting blood circulation and removing blood stasis, rouses oneself heart-yang
For the rules for the treatment of.
To realize above curative effect, the present invention includes following Chinese herbal medicine：Orange peel, the tuber of dwarf lilyturf, radix bupleuri, the bighead atractylodes rhizome, antelope's horn, Wu
The fruit of medicinal cornel, the tuber of pinellia, PORIA ALBA, the root of bidentate achyranthes, the dried rhizome of rehmannia, cassia twig, cortex acanthopanacis, the red sage root, the Radix Astragali, radix polygonati officinalis, honey-fried licorice root, ginger, jujube, its feature
It is：Each Chinese medicine parts by weight are orange peel 10-15 parts, tuber of dwarf lilyturf 6-9 part, radix bupleuri 5-8 parts, bighead atractylodes rhizome 8-12 parts, antelope's horn 8-12 parts, Wu
The fruit of medicinal cornel, 10-15 parts, tuber of pinellia 15-20 parts, PORIA ALBA 5-10 parts, root of bidentate achyranthes 8-10 parts, dried rhizome of rehmannia 12-15 parts, cassia twig 5-8 parts, cortex acanthopanacis
6-9 parts, red sage root 15-20 parts, Radix Astragali 8-12 parts, radix polygonati officinalis 10-15 parts, honey-fried licorice root 9-12 parts, ginger 5-7 parts, jujube 5-7 parts.
Preferably, optimum weight part of above-mentioned formula is：12 parts of orange peel, 8 parts of the tuber of dwarf lilyturf, 6 parts of radix bupleuri, 10 parts of the bighead atractylodes rhizome, antelope
8 parts of angle, 12 parts of evodia rutaecarpa, 20 parts of the tuber of pinellia, 8 parts of PORIA ALBA, 8 parts of the root of bidentate achyranthes, 15 parts of the dried rhizome of rehmannia, 7 parts of cassia twig, 8 parts of cortex acanthopanacis, the red sage root 15
Part, 10 parts of the Radix Astragali, 12 parts of radix polygonati officinalis, 12 parts of honey-fried licorice root, 5 parts of ginger, 5 parts of jujube.
It is wherein described：Orange peel, nature and flavor are pungent, slight bitter, temperature, returns spleen, lung channel, have qi-regulating adjust in, eliminating dampness and eliminating phlegm effect it
Effect.
The tuber of dwarf lilyturf, nature and flavor are sweet, slight bitter, are slightly cold, return lung, the heart, stomach, have Yin nourishing and lung moistening, reinforcing stomach reg fluid, the work(of relieving restlessness that clears away heart-fire
Effect.
Radix bupleuri, bitter in taste, pungent, be slightly cold, the thoughts of returning home, liver, courage, tri-jiao channel, there is evacuation to bring down a fever, soothing liver-qi stagnation, rise and lift yang-energy
The effect of.
The bighead atractylodes rhizome, bitter in taste, sweet, warm, returns spleen, stomach, have air making-up and spleen enlivening, eliminate dampness and have diuretic effect, hidroschesis, it is antiabortive the effect of.
Antelope's horn, nature and flavor are salty, cold, Return liver, the heart channel of Hang-Shaoyin, have Inflammation Zhijing, it is calming the liver, clear liver and improve vision, heat toxin hair spot it
Effect.
Evodia rutaecarpa, bitter in taste, pungent, Return liver, spleen, stomach, there is the effect of eliminating cold to stop pain, soothing the liver lower gas, inverse eliminating dampness drop.
The tuber of pinellia, nature and flavor are pungent, warm, returns spleen, stomach, lung channel, have the effect of eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.
PORIA ALBA, nature and flavor are sweet, light, flat, the thoughts of returning home, spleen, kidney channel, have the effect of clearing damp and promoting diuresis, spleen-benefiting mind-tranquilizing.
The root of bidentate achyranthes, it is bitter in taste, sour, flat, return liver and kidney channel, there is promoting blood circulation, filling liver kidney, strengthening the bones and muscles, promoting diuresis for stranguria, draw blood
The effect of descending.
The dried rhizome of rehmannia, nature and flavor are sweet, bitter, cold, the thoughts of returning home, liver and kidney channel, have the effect of clearing heat and cooling blood, nourishing Yin and promoting production of body fluid.
Cassia twig, nature and flavor are pungent, sweet, warm, the thoughts of returning home, lung, bladder warp, have the effect of inducing sweat and dispelling exogenous evils, Wen Jing activate yang.
Cortex acanthopanacis, nature and flavor are pungent, bitter, sweet, warm, return liver and kidney channel, have wind-damp dispelling, strengthen the bone, intelligence development, sharp water the effect of.
The red sage root, nature and flavor are slightly cold, are bitter, the thoughts of returning home, Liver Channel, have the effect of invigorate blood circulation, stasis-dispelling and pain-killing, relieving restlessness that clears away heart-fire.
The Radix Astragali, nature and flavor are sweet, tepor, returns spleen, lung channel, have the solid table of beneficial stomach, polishing rising Yang, promoting pus discharge and tissue regeneration, inducing diuresis for removing edema it
Effect.
Radix polygonati officinalis, nature and flavor are sweet, flat, attach to the lung and stomach meridians, have nourishing Yin and moistening lung, promote the production of body fluid nourishing the stomach the effect of.
Honey-fried licorice root, nature and flavor are sweet, flat, enter the heart, lung, spleen, stomach, have and invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, emergency
Analgesic, the effect of coordinating the drug actions of a prescription.
Ginger, nature and flavor are pungent, tepor, return lung the spleen channel, have the effect of inducing sweat and dispelling exogenous evils, warming middle energizer to stop vomiting, warm lung cough-relieving.
Jujube, nature and flavor are sweet, warm, returns spleen, stomach, have tonifying middle-Jiao and Qi, nourishing blood and tranquilization, relax the effect of property of medicine.
The orange peel, radix bupleuri, the root of bidentate achyranthes, the Radix Astragali, radix polygonati officinalis, the tuber of dwarf lilyturf, the bighead atractylodes rhizome, have qi-regulating adjust in, rise lift yang-energy, filling liver kidney,
The effect of strengthening the bones and muscles, the solid table of beneficial stomach, polishing rising Yang, promoting pus discharge and tissue regeneration, air making-up and spleen enlivening, coordinate antelope's horn, evodia rutaecarpa, the tuber of pinellia, white Fu
Siberian cocklebur, the dried rhizome of rehmannia, cassia twig, cortex acanthopanacis, the red sage root, Inflammation Zhijing, clear liver and improve vision, stasis-dispelling and pain-killing, soothing the liver lower gas, the eliminating dampness and eliminating phlegm, ruffian that disappears dissipate
The effect of knot, inducing sweat and dispelling exogenous evils, relieving restlessness that clears away heart-fire, by honey-fried licorice root, invigorate the spleen and benefit qi, relieving spasm to stop pain, coordinating the drug actions of a prescription, be equipped with ginger, jujube
To draw, warm lung cough-relieving, tonifying middle-Jiao and Qi, nourishing blood and tranquilization, the property of medicine is relaxed, there is dampness elimination to drop turbid, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass, promoting blood circulation
Stagnation resolvation, the effect of rousing oneself heart-yang.
Above-mentioned Chinese medicine obtains herb liquid according to Traditional medicine infusion method, is divided into two parts, and each portion warmly takes sooner or later, and 6 are a course for the treatment of,
Vitamin B1 is taken in cooperation, for treating beriberi cardiopathy positive effect, is verified according to clinical application for many years：It is efficient
100%, cure rate more than 98%.
Embodiment
The present invention will be further described in conjunction with the embodiments.
Embodiment, treat the medicine of beriberi cardiopathy, it is characterised in that weigh material medicine according to the following ratio：Orange peel
10-15 parts, tuber of dwarf lilyturf 6-9 part, radix bupleuri 5-8 parts, bighead atractylodes rhizome 8-12 parts, antelope's horn 8-12 parts, evodia rutaecarpa 10-15 parts, tuber of pinellia 15-20
Part, PORIA ALBA 5-10 parts, root of bidentate achyranthes 8-10 parts, dried rhizome of rehmannia 12-15 parts, cassia twig 5-8 parts, cortex acanthopanacis 6-9 parts, red sage root 15-20 parts, the Radix Astragali
8-12 parts, radix polygonati officinalis 10-15 parts, honey-fried licorice root 9-12 parts, ginger 5-7 parts, jujube 5-7 parts.
Further, as preferred plan drug ratio：12 parts of orange peel, 8 parts of the tuber of dwarf lilyturf, 6 parts of radix bupleuri, 10 parts of the bighead atractylodes rhizome, antelope
8 parts of angle, 12 parts of evodia rutaecarpa, 20 parts of the tuber of pinellia, 8 parts of PORIA ALBA, 8 parts of the root of bidentate achyranthes, 15 parts of the dried rhizome of rehmannia, 7 parts of cassia twig, 8 parts of cortex acanthopanacis, the red sage root 15
Part, 10 parts of the Radix Astragali, 12 parts of radix polygonati officinalis, 12 parts of honey-fried licorice root, 5 parts of ginger, 5 parts of jujube.
By the ginger in above-mentioned Chinese medicine preparation, jujube cotton gauze wrapped, be put into clear water soak it is standby, by orange peel,
The tuber of dwarf lilyturf, radix bupleuri, the bighead atractylodes rhizome, antelope's horn, evodia rutaecarpa, the tuber of pinellia, PORIA ALBA, the root of bidentate achyranthes, the dried rhizome of rehmannia, cassia twig, cortex acanthopanacis, the red sage root, the Radix Astragali, jade
Bamboo, honey-fried licorice root, which are put into clear water, to be soaked 60 minutes, and ginger and jujube are put into after big fire is boiled and soaked clear water, small fire endure 30 slowly
Minute, leach decoction；Adding cold water, big fire is boiled again, and small fire is endured 30 minutes slowly, leaches decoction；Two decoctions are combined into one,
Fried about 300ML altogether, is divided into two parts, and daily sooner or later each a heating warmly takes, and 6 are a course for the treatment of, during which coordinate and take vitamin
B1.2-3 course for the treatment of can sample cure beriberi cardiopathy, no longer recur.
It is as follows to the patient outcomes of beriberi cardiopathy according to long-term clinical application：
| Group | Treatment time | Number of cases | Recovery from illness | Effectively | It is invalid | It is efficient | Cure rate |
| Of the present invention group | 20-40 days | 50 | 49 | 1 | 0 | 100% | 98% |
| Control group | 20-40 days | 50 | 26 | 15 | 9 | 82% | 52% |
During clinical practice, of the present invention group, vitamin B1 is taken while medicine of the present invention is taken；Control group, only take
Vitamin B1.
By clinical practice, effective percentage 100% of the invention, cure rate more than 98% are used.
Treatment standard：Cure：Palpitaition is panted, and cyanosis on the face and lips is wandering, nausea and vomiting, and the symptoms such as fatigue is out of breath disappear,
Pulse frequency is normal, and blood pressure is normal, and percussion heart tone is normal, the sign such as no hepatomegaly, pleural effusion, seroperitoneum and hydropericardium, blood
Acetone acid content（57~125 μm of ol/L of normal value）It is normal with lactic acid concn, no recurrence；Tcm diagnosis, edema of lower extremity disappear, limb
Body is flexible, and tongue nature is ruddy, and tongue is without exception, and pulse-phase is normal.
Effectively：Weakness, fatigue, palpitaition, it is out of breath slightly, pulse frequency is quick but rarely exceeds 120 beats/min, and blood pressure is low, pulse pressure
Difference increase, percussion relativecardiac dullness is normal, or gently expands to severe, and singly one or more, which can be looked into, sees hepatomegaly, pleural effusion, abdomen
Chamber hydrops and hydropericardium sign, patient's blood acetone acid content（57~125 μm of ol/L of normal value）Or lactic acid concn slightly raises；
Tcm diagnosis, edema of lower extremity mitigate, and limbs sense of heaviness slightly subtracts, and tongue nature is ruddy, and tongue slightly whitens, and arteries and veins moistens.
It is invalid：Palpitaition asthma, cyanosis on the face and lips, wandering, nausea and vomiting, palpitaition symptom out of breath are without change, heart failure disease
There is apocleisis, Nausea and vomiting, oliguria and peripheral edema in people, and pulse frequency is quick, and blood pressure is low, pulse pressure difference increase, and percussion heart is relative
Voiced sound circle is abnormal, can look into and see hepatomegaly, pleural effusion, seroperitoneum and hydropericardium sign, patient's blood acetone acid content（Normal value
57~125 μm of ol/L）Raised with lactic acid concn；Tcm diagnosis, palpitaition asthma, cyanosis on the face and lips, edema of lower extremity is apathetic, limb
Body is heavy, and tongue nature is light fat, and white,slippery and moist fur, arteries and veins moistens.
Model case.
1. side XX, man, 22 years old, patient showed as palpitaition, out of breath, Nausea and vomiting, oliguria and peripheral edema, physical examination sun
Property sign be the high performance of body circulation vein pressure, pulse frequency is quick but rarely exceeds 120 beats/min, and blood pressure is low, but pulse pressure difference increases
Greatly, apex S3 cantering rhythms, pareordia mid systolic murmur, two base of lung moist rales, it can look into and see hepatomegaly, pleural effusion, abdominal cavity product
Liquid and hydropericardium sign, blood acetone acid content（57~125 μm of ol/L of normal value）Raise, made a definite diagnosis with tinea pedis with lactic acid concn
Characteristic of disease heart disease.Through taking 3 courses for the treatment of of this formula Chinese medicine, during which coordinate and take vitamin B1, above-mentioned symptom all disappears, without multiple
Hair.
2. king X, female, 43 years old, there is apocleisis, Nausea and vomiting, oliguria and peripheral edema, blood pressure is low, pulse pressure difference increase,
Peripheral arterial audible and pistol-shot sound, percussion relativecardiac dullness gently expand to severe, blood acetone acid content（Normal value 57~
125μmol/L）Raised with lactic acid concn, Electrocardiogram Feature QRS wave low-voltage, is made a definite diagnosis and suffered to show as nodal tachycardia
Beriberi cardiopathy.Through taking 3 courses for the treatment of of this formula Chinese medicine, during which coordinate and take vitamin B1, appropriate rest, above-mentioned symptom
All disappear, then without recurrence.
Claims (2)
1. treating the medicine of beriberi cardiopathy, it is made up of following medicine：Orange peel, the tuber of dwarf lilyturf, radix bupleuri, the bighead atractylodes rhizome, antelope's horn, Wu Zhu
Cornel, the tuber of pinellia, PORIA ALBA, the root of bidentate achyranthes, the dried rhizome of rehmannia, cassia twig, cortex acanthopanacis, the red sage root, the Radix Astragali, radix polygonati officinalis, honey-fried licorice root, ginger, jujube, its feature exist
In：Each Chinese medicine parts by weight are orange peel 10-15 parts, tuber of dwarf lilyturf 6-9 part, radix bupleuri 5-8 parts, bighead atractylodes rhizome 8-12 parts, antelope's horn 8-12 parts, Wu Zhu
Cornel 10-15 parts, tuber of pinellia 15-20 parts, PORIA ALBA 5-10 parts, root of bidentate achyranthes 8-10 parts, dried rhizome of rehmannia 12-15 parts, cassia twig 5-8 parts, cortex acanthopanacis 6-9
Part, red sage root 15-20 parts, Radix Astragali 8-12 parts, radix polygonati officinalis 10-15 parts, honey-fried licorice root 9-12 parts, ginger 5-7 parts, jujube 5-7 parts.
2. the medicine for the treatment of beriberi cardiopathy according to claim 1, it is characterised in that：The optimal weight of above-mentioned Chinese medicine
It is 12 parts of orange peel, 8 parts of the tuber of dwarf lilyturf, 6 parts of radix bupleuri, 10 parts of the bighead atractylodes rhizome, 8 parts of antelope's horn, 12 parts of evodia rutaecarpa, 20 parts of the tuber of pinellia, PORIA ALBA to measure part
8 parts, 8 parts of the root of bidentate achyranthes, 15 parts of the dried rhizome of rehmannia, 7 parts of cassia twig, 8 parts of cortex acanthopanacis, 15 parts of the red sage root, 10 parts of the Radix Astragali, 12 parts of radix polygonati officinalis, 12 parts of honey-fried licorice root,
5 parts of ginger, 5 parts of jujube.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410780891.7A CN104436140B (en) | 2014-12-17 | 2014-12-17 | Treat the medicine of beriberi cardiopathy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410780891.7A CN104436140B (en) | 2014-12-17 | 2014-12-17 | Treat the medicine of beriberi cardiopathy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104436140A CN104436140A (en) | 2015-03-25 |
| CN104436140B true CN104436140B (en) | 2018-02-06 |
Family
ID=52883400
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410780891.7A Expired - Fee Related CN104436140B (en) | 2014-12-17 | 2014-12-17 | Treat the medicine of beriberi cardiopathy |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104436140B (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1403149A (en) * | 2002-10-24 | 2003-03-19 | 河北以岭医药研究院有限公司 | Medicines composition for treating chronic heart failure and its prepn |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009097512A1 (en) * | 2008-02-01 | 2009-08-06 | Innovative Drug Discovery Inc. | Herbal pharmaceutical compositions to treat inflammation and inflammation associated conditions and diseases |
-
2014
- 2014-12-17 CN CN201410780891.7A patent/CN104436140B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1403149A (en) * | 2002-10-24 | 2003-03-19 | 河北以岭医药研究院有限公司 | Medicines composition for treating chronic heart failure and its prepn |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104436140A (en) | 2015-03-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105561214A (en) | Traditional Chinese medicine composition for treating coronary heart disease | |
| CN104642678A (en) | Female beauty tranquilizing tea and preparation method thereof | |
| CN104645249B (en) | One kind treats treating coronary heart disease and angina pectoris | |
| CN104436140B (en) | Treat the medicine of beriberi cardiopathy | |
| CN102579799A (en) | Traditional Chinese medicine composition for treating postpartum fever with blood deficiency | |
| CN104667129B (en) | A kind of drug for treating rheumatic heart disease | |
| CN104800772A (en) | Traditional Chinese medicine composition for treating vital-energy-depression type coronary heart disease and application of traditional Chinese medicine composition | |
| CN104208174A (en) | Traditional Chinese medicine composition for treating sunstroke, preparation method and application thereof | |
| CN104127680A (en) | Traditional Chinese medicine formula for treating myocarditis | |
| CN104173803B (en) | A kind of Chinese medicine preparation for treating intractable nosebleed epistaxis disease | |
| CN103948880B (en) | Traditional Chinese medicine for treating arrhythmia | |
| CN108378641A (en) | A kind of Neurology treatment pillow | |
| CN103845671B (en) | Warming YANG and invigorating QI in heart failure falls apart and preparation method | |
| CN107529439A (en) | A kind of medicine pill for treating rheumatic heart disease and preparation method thereof | |
| CN106266779A (en) | A kind of Chinese medicine of endocrine regulation imbalance | |
| CN101244194B (en) | Chinese medicine for treating scrofula disease | |
| CN105582303A (en) | Traditional Chinese medicine preparation for treating coronary heart disease | |
| CN105687656A (en) | Pharmaceutical composition for treating myelitis and preparation method thereof | |
| CN103860991B (en) | Acute heart failure invigorating QI and tranquilization electuary and preparation method | |
| CN106563054A (en) | A yang-invigorating medicine | |
| CN104474210A (en) | Traditional Chinese medicine composition for treating unstable angina pectoris caused by qi stagnation and blood stasis | |
| CN106266440A (en) | A kind of Chinese medicine composition treating blood deficiency and Qi exhaustion type post partum blood faint | |
| CN107823584A (en) | It is a kind of to treat noisy pill medicine and preparation method thereof | |
| CN104623528B (en) | Qi and activate blood circulation Yangxin Decoction | |
| CN109432305A (en) | A kind of Chinese medicine preparation for treating rhinitis, nasosinusitis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhang Ran Inventor after: Tian Xiaoyan Inventor after: Cao Yong Inventor before: Zhang Ran |
|
| COR | Change of bibliographic data | ||
| CB03 | Change of inventor or designer information |
Inventor after: Feng Defeng Inventor before: Zhang Ran Inventor before: Tian Xiaoyan Inventor before: Cao Yong |
|
| CB03 | Change of inventor or designer information | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20171123 Address after: High tech Zone 272100 Shandong city of Jining Province Wang Niangniang Temple Village South Applicant after: Jining Fengpeng Engineering Facility Co.,Ltd. Address before: Guhuai road 272000 in Shandong province Jining City No. 77 Affiliated Hospital of Jining Medical College in four families Applicant before: Zhang Ran |
|
| TA01 | Transfer of patent application right | ||
| CB03 | Change of inventor or designer information |
Inventor after: Wang Jing Inventor after: Yu Jikui Inventor before: Feng Defeng |
|
| CB03 | Change of inventor or designer information | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20180112 Address after: 276300 Yinan County People's Hospital of Linyi City, Shandong Province Applicant after: Wang Jing Applicant after: Yu Jikui Address before: High tech Zone 272100 Shandong city of Jining Province Wang Niangniang Temple Village South Applicant before: Jining Fengpeng Engineering Facility Co.,Ltd. |
|
| TA01 | Transfer of patent application right | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20180206 Termination date: 20181217 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |