CN104435800A - Traditional Chinese medicine preparation for treating epilepsy - Google Patents

Traditional Chinese medicine preparation for treating epilepsy Download PDF

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CN104435800A
CN104435800A CN201410608903.8A CN201410608903A CN104435800A CN 104435800 A CN104435800 A CN 104435800A CN 201410608903 A CN201410608903 A CN 201410608903A CN 104435800 A CN104435800 A CN 104435800A
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chinese medicine
traditional chinese
epilepsy
medicine preparation
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高小娜
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    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • AHUMAN NECESSITIES
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    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/646Arachnids, e.g. spiders, scorpions, ticks or mites
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    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884Arisaema, e.g. Jack in the pulpit
    • AHUMAN NECESSITIES
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
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    • A61K9/00Medicinal preparations characterised by special physical form
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

The invention relates to a traditional Chinese medicine preparation for treating epilepsy. The traditional Chinese medicine preparation is characterized by comprising the following traditional Chinese medicine materials in parts by weight: 10 parts of periostracum cicadae, 10 parts of centipedes, 8 parts of scorpion, 8 parts of bombys batryticatus, 30 parts of fructus trichosanthis, 9 parts of rhizoma arisaematis, 18 parts of bambusae caulis im taeniam, 12 parts of ramulus uncariae cum uncis, 8 parts of rhizoma acori tatarinowii and 10 parts of fructus aurantii. The raw material materials selected for preparing the traditional Chinese medicine preparation for treating epilepsy are complementary in drug property, avoid the mutual inhibition, mutual restraint and mutual detoxication of compatibility of medicine materials to remarkably improve the mutual reinforcement and mutual assistance of the medicine materials; and the traditional Chinese medicine preparation for treating epilepsy has the functions of relieving convulsion and spasm, expelling wind and clearing away heat, and reducing phlegm and resolving masses, and has a definite effect in treatment of epilepsy.

Description

The Chinese medicine preparation for the treatment of epilepsy
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of Chinese medicine preparation for the treatment of epilepsy.The present invention has effect of relieving spasm by subduing liver-wind, expelling wind and clearing away heat, dissipating phlegm and resolving masses, is used for the treatment of epilepsy and has definite curative effect.
Background technology
Epilepsy is chronic recurrent of short duration brain function imbalance syndrome.Cause repeatedly epilepsy outbreak for feature with brain neuron paradoxical discharge.Epilepsy is one of nervous system common disease, and prevalence is only second to apoplexy.Epileptics, because of extremely complicated, can divide three major types, and there is the factor of multiple impact morbidity: 1. idiopathy: suspected genetic tendency is without other obvious causes of disease, and certain special age bracket onset of being everlasting, has Characteristic clinical and EEG, diagnose clearer and more definite.2. symptomatic epilepsy: central nervous system pathological change affects structure or function etc., as chromosomal abnormality, focal or diffusivity brain diseases, and caused by some systemic disease.3. essential epilepsy: more common, clinical manifestation prompting symptomatic epilepsy, means the outbreak of whole-body muscle twitch and loss of consciousness.More common with maternal infuries, cerebral trauma, cerebroma etc.Tonic-clonic seizures can occur in any age, is modal seizure types in various epilepsy.Its Typical onset can be divided into the tendency phase, the tetanic phase, the clonic spasm phase, convalescent period four clinical stages.Between stage of attack, electroencephalogram is that typical explosive many spikes and sour jujube-slow wave are comprehensive, and each sour jujube-slow wave comprehensively can with muscle beat.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation for the treatment of epilepsy.The present invention has effect of relieving spasm by subduing liver-wind, expelling wind and clearing away heat, dissipating phlegm and resolving masses, is used for the treatment of epilepsy and has definite curative effect.
The technical solution used in the present invention: the raw medicinal material that the Chinese medicine preparation of described treatment epilepsy is selected and components by weight percent respectively: Periostracum Cicadae 10 parts, Scolopendra 10 parts, Scorpio 8 parts, Bombyx Batryticatus 8 parts, Fructus Trichosanthis 30 parts, Rhizoma Arisaematis 9 parts, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle eat 18 parts, Ramulus Uncariae macrophyllae 12 parts, Rhizoma Acori Graminei 8 parts, Fructus Aurantii 10 parts.
In the raw materials of traditional Chinese medicinal materials that the present invention chooses, its effect and pharmacological action respectively: Periostracum Cicadae: loose wind heat extraction, sore-throat relieving, rash, nebula removing, spasmolytic.For anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.
Scolopendra: be medicinal herbs most in use, warm in nature, acrid in the mouth is poisonous.There is the function of endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, apoplexy facial hemiparalysis, hemiplegia, tetanus disease, rheumatoid arthritis stubborn, skin infection, scrofula, venom.
Scorpio: there is " spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., antiinflammatory counteracting toxic substances, removing obstruction in the collateral to relieve pain " function; Cure mainly diseases such as " infantile convulsion, tic spasm, dermatosis, cardiovascular and cerebrovascular disease, inflammation, hepatitis B, tumors ".Scorpio is nutritious, prevents and cures diseases, enhancing immunity and anti-ageing function of waiting for a long time.
Bombyx Batryticatus: acrid in the mouth, salty, property is put down, and have expelling wind to relieve convulsion, dissipating phlegm and resolving masses, effect of heat clearing and damp drying, clinical being used for controls heat syndrome cough, phlegm dyspnea, spits blood, collapses, band, traumatic injury, rheumatalgia, sore etc.;
Fructus Trichosanthis: chemical composition: containing triterpenoid saponin, organic acid and its esters, resin, saccharide, arginine, lysine, alanine, valine, isoleucine, leucine, glycine and Alkaloid material, pigment etc.; Function cures mainly: clearing away heat and eliminating phlegm, and relieving stuffiness of the chest by dispersing aggregation of pathogens moisturizes laxation.For cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, and acute appendicitis swells and ache, constipation.
Rhizoma Arisaematis: [meridian distribution of property and flavor] is bitter, pungent, temperature; Poisonous.Return lung, liver, spleen channel; [function cures mainly] 1. drying dampness to eliminate phlegm, for the cough of cold-phlegm, damp-phlegm and pertinacious phlegm, chest and diaphragm feeling of distension and oppression.2. expelling wind to relieve convulsion, for wind-phlegm syndrome, as dizzy, middle wind-phlegm heap soil or fertilizer over and around the roots, epilepsy and tetanus etc.3. this product external, mass dissipating and swelling eliminating, for cards such as carbuncle sucutaneous nodule, arthralgias.4. for cancerous protuberance.5. control hyperlipemia.6. control children's sialorrhoea.7. control talalgia.8. control herpes zoster.9. control hordeolum.In addition, with life, fresh or dry Rhizoma Arisaematis with vinegar mill juice, put on the skin outward and control venom, smashing cake external application facial paralysis etc. with Rhizoma Arisaematis, Rhizoma Zingiberis Recens all has good therapeutic effect.
Phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle eats: nature and flavor with return through: sweet, be slightly cold.Attach to the lung and stomach meridians.Function with cure mainly: removing heat-phlegm, relieve restlessness and prevent vomiting.For phlegm-heat cough, expectorant held under the arm by gallbladder fire, and dysphoria with smothery sensation is vomitted, and eye is lost in palpitation with fear, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, frequent fetal movement.
Ramulus Uncariae macrophyllae: chemical composition is containing Ramulus Uncariae cum Uncis alkali (rhynchophylline), isorhynchophylline.Nature and flavor are cool in nature, sweet in the mouth.Function cures mainly heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion.For dizzy, dysphoric cold, the diarrhea induced by fright tic of having a headache, pregnant sub-dysentery, vascular hypertension.
Rhizoma Acori Graminei: (pungent, bitter, temperature.GUIXIN, stomach warp.Removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Not hungry for gastral cavity painful abdominal mass, a mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.Regulate the flow of vital energy, invigorate blood circulation, loose wind, dries.Control epilepsy, syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, ambition is unhappy, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.Rhizome and Ye Zhongjun are containing volatile oil (0.11% ~ 0.42%) and saccharide, organic acid, aminoacid etc.Containing 34 kinds of compositions in volatile oil, its main component is beta-Asarone (β-Asarone), accounts for 63.2% ~ 81.2%; α-asaricin (α-Asarone), accounts for 3.4% ~ 13.7%; Secondly be caryophyllene (Caryophyllene), α-Humuleno (α-Humulene), sekishone (Sekishone), asarylaldehyde (Asarylaldehyde), elemicin (Elemicine), euasarone (Euasarone), 1-pi-allyl-2,4,5-trimethoxy-benzene (1-Allyl-2,4,5-trimethoxy benzene), methyleugenol (Methyleugenol), cis methyl tert-butyl Oleum sesami phenol, transmethyl isoeugenol (trans-Methylisoeugenol) etc.
Fructus Aurantii (parched): the dry immature fruit of rutaceae Citrus aurantium Linn. Citrus aurantium L. and variety thereof.Nature and flavor are bitter; Acid; Cold nature is returned through lung; Spleen; Liver; Stomach; Large intestine channel function cures mainly: septum pectorale feeling of fullness; Distending pain over the hypochondrium; Accumulation of food in the stomach and intes tine due to indigestion; Distension and fullness in the abdomen; Heavy after dysentery; Proctoptosis; Uterine prolapse.
Complementary with the raw medicinal material property of medicine effect selected by top, evade the choosing of the mutual inhibition of compatibility between medicine, mutual restraint between two drugs, the mutual-detoxication, made medicine mutual reinforcement between, mutual-assistance effect significantly, there is effect of relieving spasm by subduing liver-wind, expelling wind and clearing away heat, dissipating phlegm and resolving masses, be used for the treatment of epilepsy, there is definite curative effect.Clinical practice has good precise effects:
The model case of clinical practice of the present invention:
Tight XX, man, 37 years old.May 21 2007 first visit date.
Patient is existing epilepsy history many years ago, but attack times is less, every outbreak in 1 year 1 time, and instantaneous i.e. mistake at every turn.From the beginning of this year, outbreak is frequent, within 1 hour sometimes, can occur 2 times, during petit mal, only has mind to stare blankly, a few second and mistake, have baa during grand mal, gnathospasma, the eyes turning upwards, two fists are held, obnubilation, whole body is twitched, and spits out white foams, and lasting half an hour, right and left can be alleviated.Feeling of fullness in the head is uncomfortable in chest at ordinary times, and abundant expectoration sticks greasy, dry stool yellowish urine, thick and greasy fur, stringy and rolling pulse.This holds expectorant under the arm with gas superinverse for liver-wind, and it is sick that clear key is caused into epilepsy by illiteracy, should relieving spasm by subduing liver-wind, expelling wind and clearing away heat, dissipating phlegm and resolving masses master it.After clothes we 15 doses, spirit takes a turn for the better, and amount of expectoration reduces, and does not reaccess.Continue to take we 10 doses, consolidated.
Method and effective dose: Periostracum Cicadae 10 parts, Scolopendra 10 parts, Scorpio 8 parts, Bombyx Batryticatus 8 parts, Fructus Trichosanthis 30 parts, Rhizoma Arisaematis 9 parts, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle eat 18 parts, Ramulus Uncariae macrophyllae 12 parts, Rhizoma Acori Graminei 8 parts, Fructus Aurantii 10 parts; Get prescription ormal weight tcm and herbal slice, put in suitable decocting device, add clear water appropriate, soak suitable time, be heated to boil, keep slight boiling condition certain hour (about 25 ~ 30 minutes), be separated fried liquid, medicinal residues add water and decoct in right amount, after regulation decoction 2 ~ 3 times, merge fried liquid, filter or settlement separate fried liquid for.
Decoction oral is main, and every day takes orally for 2 times sooner or later, each 150ml decoction being taken warmly.Decoction then acts on fast and power is high, is adapted to the more anxious severe one of the state of an illness.As lighter in the state of an illness or slow person, is preferably that pill is for oral administration asks its merit.
Detailed description of the invention
The described Chinese medicine preparation being used for the treatment of epilepsy, it is characterized in that, the raw material of Chinese medicine of selection and weight portion respectively: Periostracum Cicadae 10 parts, Scolopendra 10 parts, Scorpio 8 parts, Bombyx Batryticatus 8 parts, Fructus Trichosanthis 30 parts, Rhizoma Arisaematis 9 parts, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle eat 18 parts, Ramulus Uncariae macrophyllae 12 parts, Rhizoma Acori Graminei 8 parts, Fructus Aurantii 10 parts;
Preparation method: get Periostracum Cicadae 10 parts, Scolopendra 10 parts, Scorpio 8 parts, Bombyx Batryticatus 8 parts, Fructus Trichosanthis 30 parts, Rhizoma Arisaematis 9 parts, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle eat 18 parts, Ramulus Uncariae macrophyllae 12 parts, Rhizoma Acori Graminei 8 parts, Fructus Aurantii 10 parts; Ormal weight Chinese crude drug makes decoction pieces, put in suitable decocting device, add clear water appropriate, soak suitable time, be heated to boil, keep slight boiling condition certain hour (about 25 ~ 30 minutes), be separated fried liquid, medicinal residues add water and decoct in right amount, after regulation decoction 2 ~ 3 times, merge fried liquid, filter or settlement separate fried liquid for.

Claims (1)

1. treat the Chinese medicine preparation of epilepsy for one kind, it is characterized in that, the raw material of Chinese medicine of selection and weight portion respectively: Periostracum Cicadae 10 parts, Scolopendra 10 parts, Scorpio 8 parts, Bombyx Batryticatus 8 parts, Fructus Trichosanthis 30 parts, Rhizoma Arisaematis 9 parts, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle eat 18 parts, Ramulus Uncariae macrophyllae 12 parts, Rhizoma Acori Graminei 8 parts, Fructus Aurantii 10 parts;
Preparation method: get Periostracum Cicadae 10 parts, Scolopendra 10 parts, Scorpio 8 parts, Bombyx Batryticatus 8 parts, Fructus Trichosanthis 30 parts, Rhizoma Arisaematis 9 parts, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle eat 18 parts, Ramulus Uncariae macrophyllae 12 parts, Rhizoma Acori Graminei 8 parts, Fructus Aurantii 10 parts; Ormal weight Chinese crude drug makes decoction pieces, put in suitable decocting device, add clear water appropriate, soak suitable time, be heated to boil, keep slight boiling condition certain hour (about 25 ~ 30 minutes), be separated fried liquid, medicinal residues add water and decoct in right amount, after regulation decoction 2 ~ 3 times, merge fried liquid, filter or settlement separate fried liquid for.
CN201410608903.8A 2014-10-27 2014-10-27 Traditional Chinese medicine preparation for treating epilepsy Pending CN104435800A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031369A (en) * 2015-08-28 2015-11-11 辛晓林 Medicine for treating epilepsy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031369A (en) * 2015-08-28 2015-11-11 辛晓林 Medicine for treating epilepsy

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