CN104435786A - Formula for acne removal liquid - Google Patents
Formula for acne removal liquid Download PDFInfo
- Publication number
- CN104435786A CN104435786A CN201310420570.1A CN201310420570A CN104435786A CN 104435786 A CN104435786 A CN 104435786A CN 201310420570 A CN201310420570 A CN 201310420570A CN 104435786 A CN104435786 A CN 104435786A
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- China
- Prior art keywords
- acne
- metronidazole
- erythromycin
- removal liquid
- acne removal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
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- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to a formula for acne removal liquid, which belongs to the acne removal technology field. The formula comprises the following components with mass percentage: 92.5-95% of special corn wine, 1.7-2.5% of erythromycin and 3.3-5% of metronidazole. The method for preparing the acne removal liquid comprises the following steps: preparing the special corn wine by a traditional distillation method and taking as a base of the acne removal liquid, preparing erythromycin and metronidazole at pressurization and heating environment that temperature is 60-80 DEG C and pressure is 1.06-1.1*10e<5>pa, mixing three components under normal temperature and normal pressure and then uniformly stirring, mixing, bottling and sealing to obtain the product. The acne removal liquid has the advantage of convenient usage and has good curative effect for removing acnes, has functions for treating acnes and disinfecting for conditioning skin, effect is obvious, action is fast, no acne trace is generated after recovery, recurrence is difficult, and the acne removal liquid has the functions of skin tendering, moisture retention, grease secrete reduction, and cell metabolism promotion.
Description
technical field
The present invention relates to a kind of acne-removing liquid formula, belong to acne-removing liquid formulation art.
Background technology
Small pox Producing reason is varied, and skin belongs to oily skin, and sebaceous gland is too flourishing, sebum secretion is excessively prosperous, and the blocked or other reasons of pore causes oil extraction smooth, when sebaceous gland continues secretion, sebum is just accumulated in pore, and projection, becomes small pox then.Internal cause is that hormone in vivo secretion is unbalance, makes the long comedo of skin.Hormone secretion is unbalance also can cause sebum secretion too vigorous indirectly, directly causes clogging of pores, produces comedo rapidly.The comedo of most people is all caused by above-mentioned reason, so, thoroughly to treat comedo, in anti-acne, need set about from following several respects: the moistening effect 1) improving skin; 2) the oils and fats balance of regulation of skin, suppresses the too much secretion of sebum; 3) breeding of seat skin ulcer propionibacterium is suppressed; 4) there is certain antiinflammatory action; 5) pox print is dispelled; 6) endocrine regulation.
In existing patented technology, some are also had to relate to formula for anti-acne and method.As disclosed a kind of acne-removing liquid in patent " a kind of acne-removing liquid " (publication number: 103006527A), comprise following component: component A: propylene glycol, HANSHENGJIAO, the first solvent; B component: two isethionic acid hexyl ethers, vitamin B6, the second solvent; Component C: plant extraction liquid, azelaic acid derivant, Herba Dendranthematis indici dimension element, salicylic acid, Radix Ginseng extract, vitamin E, antiseptic.Patent " a kind of anti-acne essence adding pearl hydrolysate liposome " (publication number: 101288640) disclose a kind of anti-acne essence adding pearl hydrolysate liposome; be by glycerol, 1,3 butanediols, disodiumedetate, pearl hydrolysate liposome, phytosphingosine, glycyrrhizic acid dipotassium, extremely U.S. and deionized water are prepared from through mix and blend; Its preparation technology is by glycerol, 1,3 butanediols, disodiumedetate, deionized water mixing and stirring, after heating, insulation, cooling, add pearl hydrolysate liposome, phytosphingosine, glycyrrhizic acid dipotassium, extremely beautiful and stir, discharging obtains finished product.These acne-removing liquids are all often adopt a series of chemical drugs through processing, and there are some effects for anti-acne, but, still can not fundamentally anti-acne, to this, the present invention is according to the characteristic of small pox itself, be configured with new prescription, there is the effect of good antiphlogistic antibacterial and anti-acne.
Summary of the invention
The object of the present invention is to provide a kind of acne-removing liquid, can Bergamot Mint Extract, deep layer conditioning skin, correct metabolism disorder, strengthening skin metabolism, improves skin microcirculation ecological environment, antiinflammatory, kills flora, thus effective anti-acne.
In order to achieve the above object, the solution of the present invention is as follows:
A kind of acne-removing liquid formula, comprise speciality corn wine, erythromycin, metronidazole, its proportioning is, according to mass percent is: speciality corn wine is 92.5 ~ 95%, erythromycin is 1.7 ~ 2.5%, metronidazole is 3.3 ~ 5%.
Wherein, speciality corn wine adopts way of distillation traditional handicraft, remains on 45 ~ 50 degree.
The concrete manufacture method of this acne-removing liquid is: the processing technique of special corn wine is produced with Conventional espresso method, as the medicine base of acne-removing liquid, erythromycin, metronidazole temperature be 60 ~ 80 degree, pressure is 1.06 ~ 1.1 * 10e
5pa is prepared in the environment of Pressurized-heated, at normal temperatures and pressures by these three kinds of composition mixing and stirring after completing, and mixing bottling sealing.
The traditional Chinese medical science is thought, the flat sweet in the mouth of Semen Maydis, has the effects such as appetizing, spleen invigorating, dehumidifying, diuresis, cures mainly diarrhoea, dyspepsia, edema etc.According to trophic analysis, Semen Maydis contains carbohydrate, protein, carotene, lutein, cryptoxanthin, phosphorus, magnesium, potassium, zinc etc.Semen Maydis is that fermentation industry provides the abundant and carbohydrate of economy.By the glucose that enzymolysis generates, it is the very good material of fermentation industry.The side-product of processing, produces the multiple product perhaps such as ethanol, medicated beer as corn steep liquor, powder slurry etc. all can be used for fermentation industry.Therefore the corn wine preparing gained has good health therapy function, and in this product, special corn wine plays the effect of effective ingredient rapid osmotic in the product.
Erythromycin is macrolide antibiotics, to gram positive bacteria, as staphylococcus, micrococcus scarlatinae, viridans streptococci, streptococcus pneumoniae, streptococcus faecalis, Hemolytic streptococcus, clostridium, diphtheria corynebacterium, anthrax bacillus etc. have stronger inhibitory action.To gram-negative bacteria, as gonococcus, pylori, bordetella pertussis, Brucella, legionella, meningococcus and hemophilus influenza, bacteroid, part dysentery bacterium and escherichia coli etc. also have certain inhibitory action.In addition, to mycoplasma, actinomycetes, spirillum, rickettsia, chlamydia, slave blocks bacterium, minority mycobacteria and ameba inhibitory action.
Metronidazole has another name called metronidazole, metronidazole, to most of anaerobe, there is powerful antibacterial action, but to aerobe and facultative anaerobe without work, antimicrobial spectrum comprises bacteroides fragilis, with other bacteroids, fusiform bacilarmature, aerogenesis clostruidium, Eubacterium, Wei Rong coccus, dyspepsiacoccus and peptostreptococcus etc., actinomyces, Lactobacillus, propionibacterium are to this product drug resistance.It kills a little higher than Mlc of concentration.It has antibacterial wide, the advantage such as sterilizing power strong, and toxic and side effects is few, has no drug resistance, and dosage form is various, and medication is convenient.Therefore clinical play a part very important.
Beneficial effect of the present invention is: in this invention, corn wine is utilized to make medicine base, and erythromycin, metronidazole dissolve play in the product Bergamot Mint Extract, deep layer conditioning skin, correct metabolism disorder, strengthening skin metabolism, improve skin microcirculation ecological environment, antiinflammatory, kill flora effect.This medicine mixing bottling sealing, easy to use, to anti-acne, there is good curative effect effect, there is the function for the treatment of comedo and sterilization conditioning skin simultaneously, successful, effect is fast, without pockmark more, be not easy recurrence, and have the function of skin care, moisturizing, minimizing fat secretion, promotion cellular metabolism concurrently.
Detailed description of the invention
embodiment one
A kind of acne-removing liquid formula, comprise speciality corn wine, erythromycin, metronidazole, its proportioning is, according to mass percent is: speciality corn wine is 92.5%, erythromycin is 2.5%, metronidazole is 5%.
Wherein, speciality corn wine adopts way of distillation traditional handicraft, remains on 45 degree.
The concrete manufacture method of this acne-removing liquid is: the processing technique of special corn wine is produced with Conventional espresso method, as the medicine base of acne-removing liquid, erythromycin, metronidazole temperature be 60 degree, pressure is 1.1 * 10e
5pa is prepared in the environment of Pressurized-heated, at normal temperatures and pressures by these three kinds of composition mixing and stirring after completing, and mixing bottling sealing.
embodiment two
A kind of acne-removing liquid formula, comprise speciality corn wine, erythromycin, metronidazole, its proportioning is, according to mass percent is: speciality corn wine is 95%, erythromycin is 1.7%, metronidazole is 3.3%.
Wherein, speciality corn wine adopts way of distillation traditional handicraft, remains on 50 degree.
The concrete manufacture method of this acne-removing liquid is: the processing technique of special corn wine is produced with Conventional espresso method, as the medicine base of acne-removing liquid, erythromycin, metronidazole temperature be 80 degree, pressure is 1.06*10e
5pa is prepared in the environment of Pressurized-heated, at normal temperatures and pressures by these three kinds of composition mixing and stirring after completing, and mixing bottling sealing.
embodiment three
A kind of acne-removing liquid formula, comprise speciality corn wine, erythromycin, metronidazole, its proportioning is, according to mass percent is: speciality corn wine is 94%, erythromycin is 2%, metronidazole is 4%.
Wherein, speciality corn wine adopts way of distillation traditional handicraft, remains on 48 degree.
The concrete manufacture method of this acne-removing liquid is: the processing technique of special corn wine is produced with Conventional espresso method, as the medicine base of acne-removing liquid, erythromycin, metronidazole temperature be 70 degree, pressure is 1.08*10e
5pa is prepared in the environment of Pressurized-heated, at normal temperatures and pressures by these three kinds of composition mixing and stirring after completing, and mixing bottling sealing.
Claims (3)
1. an acne-removing liquid formula, is characterized in that: comprise speciality corn wine, erythromycin, metronidazole, and its proportioning according to mass percent is: speciality corn wine is 92.5 ~ 95%, erythromycin is 1.7 ~ 2.5%, metronidazole is 3.3 ~ 5%.
2. a kind of acne-removing liquid formula according to claim 1, is characterized in that: described speciality corn wine adopts the preparation of way of distillation traditional handicraft, remains on 45 ~ 50 degree.
3. a kind of acne-removing liquid formula according to claim 1, it is characterized in that: the concrete manufacture method of described acne-removing liquid is: the processing technique of special corn wine is produced with Conventional espresso method, as the medicine base of acne-removing liquid, erythromycin, metronidazole temperature be 60 ~ 80 degree, pressure is 1.06 ~ 1.1 * 10e
5pa is prepared in the environment of Pressurized-heated, at normal temperatures and pressures by these three kinds of composition mixing and stirring after completing, and mixing bottling sealing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310420570.1A CN104435786A (en) | 2013-09-16 | 2013-09-16 | Formula for acne removal liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310420570.1A CN104435786A (en) | 2013-09-16 | 2013-09-16 | Formula for acne removal liquid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104435786A true CN104435786A (en) | 2015-03-25 |
Family
ID=52883047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310420570.1A Pending CN104435786A (en) | 2013-09-16 | 2013-09-16 | Formula for acne removal liquid |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104435786A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1628631A (en) * | 2004-09-02 | 2005-06-22 | 刘洪福 | Pox removing cream |
| US20130267486A1 (en) * | 2010-11-01 | 2013-10-10 | Stiefel Research Australia Pty Ltd. | Polymeric topical compositions |
-
2013
- 2013-09-16 CN CN201310420570.1A patent/CN104435786A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1628631A (en) * | 2004-09-02 | 2005-06-22 | 刘洪福 | Pox removing cream |
| US20130267486A1 (en) * | 2010-11-01 | 2013-10-10 | Stiefel Research Australia Pty Ltd. | Polymeric topical compositions |
Non-Patent Citations (2)
| Title |
|---|
| 王碧江等: "静肤平中甲硝唑与红霉素的含量测定", 《药学实践杂志》 * |
| 田兴秀等: "《苗族医药学》", 31 December 1995, 云南民族出版社 * |
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| PB01 | Publication | ||
| EXSB | Decision made by sipo to initiate substantive examination | ||
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Application publication date: 20150325 |