Background technology
Easily there is the diseases such as yellow urine disease, pyosapremia, fungal skin disease and diarrhoeal diseases in young rabbit, once morbidity, being difficult to cure, is the several large difficult problem in producing.
Young rabbit Huang urine is sick also known as young rabbit acute enteritis, caused by staphylococcus aureus and toxin thereof.Young rabbit feeds the milk sucking and suffer from the female rabbit of mastitis and causes a disease, and often broodly occurs together, sick rabbit lethargy, and whole body feels like jelly, perianal and hind leg are stain by yellow water sample loose stool, stench unpleasant, the course of disease 2 ~ 3 days, mortality rate is very high, in addition, also can cause young rabbit Huang urine disease owing to padding careless moist dirt.The method of traditional treatment young rabbit Huang urine disease is with penicillin or chloromycetin eyedrops, drips every day and feeds young rabbit 1 ~ 2 time, each 1 ~ 2, forbid that young rabbit feeds and eat female rabbit milk during treatment.The method curative effect is low, and owing to can not eat female rabbit milk, need artificial milk powder to raise, feeding cost is high.
Young rabbit pyaemia septica majority has infection of staphylococcus aureus skin to cause subcutaneous little pustule, thereafter pathogenic bacterium invade growth and breeding in the circulation of young Sanguis Leporis seu oryctolagi, produce toxin and the acute systemic infection caused by other metabolites, the acute systemic infection that pathogenic microorganism causes from wound or In vivo infection focus intrusion blood, suffer from rabbit case fatality rate and can reach more than 50%, break through's majority loses Feeding value.The Therapeutic Method of this disease mainly uses antibiotic, and curative effect is not high.
Rabbit body surface mycosis has another name called skin fungus disease, depilation tinea etc., is a kind of high degree in contact sexually transmitted disease caused by trichophyton or size spore fungal infection skin surface and accessory structure hair follicle thereof and hair shaft.At present, the still not effective medicine of this disease, puts prevention first with the sterilization of rabbit home.
Young rabbit diarrhoeal diseases majority is that case, pad are careless owing to producing, cage tool and the environment pathogenic bacterial infection caused such as unhygienic, moist cause digestive system diseases associated with inflammation.Sick rabbit loss of appetite, activity reduces, and arrange rare soft stool, medicated porridge sample just or watery stool, pollute rear quarters by hair, tarnish, mortality rate is higher.Common antibiotics or this disease of chemotherapy in production, but poor effect, side effect is obvious.
At present, not yet have a kind of can the pharmaceutical composition of simultaneously prevention and therapy young rabbit Huang urine disease, pyosapremia, fungal skin disease and diarrhoeal diseases.
Summary of the invention
The object of the present invention is to provide the health-care sand of a kind of Prevention and Curation young rabbit Huang urine disease, pyosapremia, fungal skin disease and diarrhoeal diseases.
A kind of young rabbit health-care sand, is made up of the component of following parts by weight: salicylic acid 20 ~ 30 parts, bactrim 15 ~ 25 parts, calcium propionate 15 ~ 25 parts, Pulvis Talci 920 ~ 950 parts.
Preferably, be made up of the component of following parts by weight: salicylic acid 25 parts, bactrim 20 parts, calcium propionate 20 parts, Pulvis Talci 935 parts.
The preparation method of young rabbit health-care sand: above-mentioned raw materials component coordinated according to part by weight, fully stir, then subpackage, vacuum seal, lucifuge drying place preserves.
The using method of young rabbit health-care sand: before female rabbit farrowing, get above-mentioned young rabbit health-care sand 4-6g, the pad grass surface of uniformly dispersing in product case, each product case scatters once, if high-temperature high humidity season or the larger warren of humidity, supplement when young rabbit 10-20 days and scatter once.
Pad grass surface area in described product case is 0.1-0.15m
2.
The application of above-mentioned young rabbit health-care sand in prevention and therapy young rabbit Huang urine disease, pyosapremia, fungal skin disease and diarrhoeal diseases.
Beneficial effect of the present invention: young rabbit health-care sand preparation method of the present invention is simple, raw material sources are wide, effectively can prevent the generation of young rabbit Huang urine disease, pyosapremia, fungal skin disease and diarrhoeal diseases, also these diseases can effectively be treated, that a kind of cost is low, the compositions that prevention and therapy efficiency is high, improves young rabbit survival rate, has saved the rabbit treatment spending of rabbit warren.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be further described.
Embodiment 1
A kind of young rabbit health-care sand, is made up of the component of following parts by weight: salicylic acid 25 parts, bactrim 20 parts, calcium propionate 20 parts, Pulvis Talci 935 parts.
The preparation method of above-mentioned young rabbit health-care sand: above-mentioned raw materials component coordinated according to part by weight, fully stir, then subpackage, vacuum seal, lucifuge drying place preserves.
The using method of above-mentioned young rabbit health-care sand: before female rabbit farrowing, get above-mentioned young rabbit health-care sand 5g, the pad grass surface of uniformly dispersing in product case, each product case scatters once, if high-temperature high humidity season or the larger warren of humidity, supplement when young rabbit 15 days and scatter once.Pad grass surface area in described product case is 0.12m
2.
Embodiment 2
A kind of young rabbit health-care sand, is made up of the component of following parts by weight: salicylic acid 20 parts, bactrim 15 parts, calcium propionate 15 parts, Pulvis Talci 920 parts.
The preparation method of above-mentioned young rabbit health-care sand: above-mentioned raw materials component coordinated according to part by weight, fully stir, then subpackage, vacuum seal, lucifuge drying place preserves.
The using method of above-mentioned young rabbit health-care sand: before female rabbit farrowing, get above-mentioned young rabbit health-care sand 5g, the pad grass surface of uniformly dispersing in product case, each product case scatters once, if high-temperature high humidity season or the larger warren of humidity, supplement when young rabbit 15 days and scatter once.Pad grass surface area in described product case is 0.12m
2.
Embodiment 3
A kind of young rabbit health-care sand, is made up of the component of following parts by weight: salicylic acid 30 parts, bactrim 25 parts, calcium propionate 25 parts, Pulvis Talci 950 parts.
The preparation method of above-mentioned young rabbit health-care sand: above-mentioned raw materials component coordinated according to part by weight, fully stir, then subpackage, vacuum seal, lucifuge drying place preserves.
The using method of above-mentioned young rabbit health-care sand: before female rabbit farrowing, get above-mentioned young rabbit health-care sand 5g, the pad grass surface of uniformly dispersing in product case, each product case scatters once, if high-temperature high humidity season or the larger warren of humidity, supplement when young rabbit 15 days and scatter once.Pad grass surface area in described product case is 0.15m
2.
The preventive effect adopting the compositions described in embodiment 1-3 and using method to urinate disease, pyosapremia, fungal skin disease and diarrhoeal diseases to young rabbit Huang is as follows:
Prevent young rabbit Huang urine disease: carry out contrast test to 3 sick serious warrens of yellow urine, result is as shown in table 1, and preventive effect reaches extremely significant level:
The preventive effect that table 1 young rabbit health-care sand is sick to young rabbit Huang urine
Prevent young rabbit pyaemia septica: contrast test is carried out in the warren more serious to 5 young rabbit pyaemia septicas, and result is as shown in table 2, preventive effect reaches extremely significant level:
Table 2 health-care sand is to the preventive effect of young rabbit pyaemia septica
Prevention dermatomycosis: contrast test has been carried out in the warren that there occurs dermatomycosis at 7, and result is as shown in table 3, preventive effect reaches extremely significant level:
Table 3 health-care sand is to the mycotic preventive effect of young rabbit skin
Prevent young rabbit diarrhoeal diseases: the contrast test of having carried out the young rabbit diarrhoea of prevention in 12 warrens, result is as shown in table 4, and preventive effect reaches extremely significant level:
Table 4 health-care sand is to the preventive effect of young rabbit diarrhoeal diseases
Comparative example 1
A kind of compositions, is made up of the component of following parts by weight: bactrim 15 parts, calcium propionate 15 parts, Pulvis Talci 920 parts.
The preparation method of above-mentioned composition: above-mentioned raw materials component coordinated according to part by weight, fully stir, then subpackage, vacuum seal, lucifuge drying place preserves.
The using method of above-mentioned composition: before the farrowing of female rabbit, get above-mentioned young rabbit health-care sand 5g, uniformly dispersing is producing the grass of the pad in case surface, and each product case scatters once, if high-temperature high humidity season or the larger warren of humidity, supplements distribution once when young rabbit 15 days.Pad grass surface area in described product case is 0.1m
2.
Comparative example 2
A kind of compositions, is made up of the component of following parts by weight: salicylic acid 20 parts, calcium propionate 15 parts, Pulvis Talci 920 parts.
The preparation method of above-mentioned composition: above-mentioned raw materials component coordinated according to part by weight, fully stir, then subpackage, vacuum seal, lucifuge drying place preserves.
The using method of above-mentioned composition: before the farrowing of female rabbit, get above-mentioned young rabbit health-care sand 5g, uniformly dispersing is producing the grass of the pad in case surface, and each product case scatters once, if high-temperature high humidity season or the larger warren of humidity, supplements distribution once when young rabbit 15 days.Pad grass surface area in described product case is 0.1m
2.
Comparative example 3
A kind of compositions, is made up of the component of following parts by weight: salicylic acid 20 parts, bactrim 15 parts, Pulvis Talci 920 parts.
The preparation method of above-mentioned composition: above-mentioned raw materials component coordinated according to part by weight, fully stir, then subpackage, vacuum seal, lucifuge drying place preserves.
The using method of above-mentioned composition: before the farrowing of female rabbit, get above-mentioned young rabbit health-care sand 5g, uniformly dispersing is producing the grass of the pad in case surface, and each product case scatters once, if high-temperature high humidity season or the larger warren of humidity, supplements distribution once when young rabbit 15 days.Pad grass surface area in described product case is 0.1m
2.
The preventive effect adopting the compositions described in comparative example 1-3 and using method to urinate disease, pyosapremia, fungal skin disease and diarrhoeal diseases to young rabbit Huang is as follows:
Prevent young rabbit Huang urine disease: carry out contrast test to 3 sick serious warrens of yellow urine, result is as shown in table 5, and comparative example 1-2 preventive effect is not obvious, comparative example 3 successful, but effect is poorer than embodiment 1-3:
The preventive effect that table 5 compositions is sick to young rabbit Huang urine
Prevent young rabbit pyaemia septica: contrast test is carried out in the warren more serious to 5 young rabbit pyaemia septicas, and result is as shown in table 6, and comparative example 1-2 preventive effect is not obvious, comparative example 3 successful, but effect is poorer than embodiment 1-3:
Table 6 compositions is to the preventive effect of young rabbit pyaemia septica
Prevention dermatomycosis: contrast test has been carried out in the warren that there occurs dermatomycosis at 7, and result is as shown in table 7, and comparative example 1-2 preventive effect is not obvious, comparative example 3 successful, but effect is poorer than embodiment 1-3:
Table 7 compositions is to the mycotic preventive effect of young rabbit skin
Prevent young rabbit diarrhoeal diseases: the contrast test of having carried out the young rabbit diarrhoea of prevention in 12 warrens, result is as shown in table 8, and comparative example 1-2 preventive effect is not obvious, comparative example 3 successful, but effect is poorer than embodiment 1-3:
Table 8 compositions is to the preventive effect of young rabbit diarrhoeal diseases