CN104434004A - Capsule endoscope detection system and image information processing method - Google Patents
Capsule endoscope detection system and image information processing method Download PDFInfo
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- CN104434004A CN104434004A CN201410838789.8A CN201410838789A CN104434004A CN 104434004 A CN104434004 A CN 104434004A CN 201410838789 A CN201410838789 A CN 201410838789A CN 104434004 A CN104434004 A CN 104434004A
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- capsule endoscope
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
- A61B1/041—Capsule endoscopes for imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00002—Operational features of endoscopes
- A61B1/00004—Operational features of endoscopes characterised by electronic signal processing
- A61B1/00009—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00002—Operational features of endoscopes
- A61B1/00011—Operational features of endoscopes characterised by signal transmission
- A61B1/00016—Operational features of endoscopes characterised by signal transmission using wireless means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00002—Operational features of endoscopes
- A61B1/0002—Operational features of endoscopes provided with data storages
- A61B1/00022—Operational features of endoscopes provided with data storages removable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00002—Operational features of endoscopes
- A61B1/00025—Operational features of endoscopes characterised by power management
Abstract
The invention relates to a medical diagnostic apparatus, in particular to a capsule endoscope detection system and a processing method for image information collected by the system. A communication emission port of a capsule endoscope is set to be a Bluetooth function port or a WIFI function port, experiment image information is directly transmitted to a common smart phone or a laptop, and therefore the capsule endoscope can be conveniently used by a patient and can be conveniently popularized. The processing method for the image information is a self diagnosis method, according to the method, firstly a person without a medical science background or a patient himself or herself selects suspected lesion images, and then the selected suspected lesion images are diagnosed by a special doctor. The method can greatly reduce the workload of doctors, lower inspection cost and improve work efficiency of the doctors.
Description
Technical field
The present invention relates to a kind of medical diagnostic device, particularly relate to the processing method of the image information of a kind of capsule endoscope detection system and this system acquisition.
Background technology
The endoscopic procedure that Israel scientist Iddan tells about according to an internist, creates the initial imagination of development wireless endoscope, and obtains patent the nineties in last century.After this, Given Imaging company adopts this patented technology, produces first capsule endoscopic in the world, and drops into Clinical practice.This technology has filled up the blank of small intestinal visuality, woundless testing means, has started new era of digestive system wireless endoscope diagnosis.
From appearance, capsule endoscope and common capsule for medicine are distinguished not quite, but it is a microcam, for spying upon the health status at human body the intestines and stomach and esophagus position.After intelligent capsule is swallowed by patient as taking medicine, namely it run along the direction of esophagus, Stomach duodenum, jejunum and ileum, colon, rectum, makes a video recording continuously to the tract of process simultaneously, and image is passed to the image recorder carried outside patient body.The capsule endoscope working time reaches 6 ~ 8 hours, will excrete after swallowing 8 ~ 72 hours with feces.The image that doctor is recorded by image workstation analysis image recorder, just can understand the whole gastral situation of patient, thus make diagnosis to the state of an illness.Capsule endoscope extends the visual field of digestive tract examining, overcome the toleration that traditional plug-in type endoscope has poor, be not suitable for the defects such as elderly and infirm, can be used as the prefered method of digestive tract disease especially diagnosis of small bowel diseases.
Inspection fee is relatively costly, and general patient is difficult to bear, and the inspection fee of a domestic current capsule endoscope is about 4000 yuan, and general single health check-up total cost is about 1000 yuan, and therefore this inspection cannot list routine physical examination project in.This expense checked is about as much as 8 times of common CT examination expense, and general patient is also difficult to bear.Capsule Endoscopy is costly, mainly contains two reasons: one is that a whole set of capsule endoscope system equipment manufacturing cost is higher, and domestic system generally reaches hundreds thousand of unit, and imported product is then higher; That import checks that capsule is then more expensive because check that the producer price of capsule remains high, domestic inspection capsule price about about 2000 yuan more in addition.
There is ratio shared by the picture of diagnostic significance less.The alimentary tract endoscope image that general capsule endoscope inspection produces nearly several ten thousand even hundreds of thousands open, and the image with diagnostic value comprising focus often only has tens.But when diagnosis, doctor then needs all images traveling through capsule endoscope collection, find the image with diagnostic value also to make diagnosis accordingly, this is a job of wasting time and energy very much, directly affects the work efficiency of clinician.Therefore, from several ten thousand two field pictures, the image screened containing possible pathological changes and focus just becomes very meaningful automatically.At present, image workstation generally provide only original image playback and some auxiliary read tablet functions, pattern distortion rectification, denoising, motion blur recovery and enhancing etc. are then mainly comprised in image processing process, and the less application with real effectively minimizing image data amount.
Existing capsule endoscope technology and diagnostic mode greatly constrain this universal and application diagnosed, and make so advanced diagnostic means cannot benefit the more vast masses.Therefore, how to improve existing capsule endoscope technology, even change existing diagnostic mode, thus break its intrinsic 'bottleneck' restrictions, capsule endoscope technical field urgent problem just.
Summary of the invention
The object of the invention is to avoid the deficiencies in the prior art part and provide a kind of can avoiding to concentrate by special-purpose computer work station the processing method receiving the capsule endoscope detection system of process capsule endoscope image information and the image information of this detection system collection.
Capsule endoscope detection system of the present invention, comprise capsule endoscope and portable mobile apparatus terminal, described capsule endoscope comprises cmos image sensor, central control unit, the first wireless communication port and power supply, and described mobile device terminal comprises the second wireless communication port and control unit, described power supply is cmos image sensor, central control unit and the first wireless communication port provide electric energy, described cmos image sensor gathers image information and image information is transferred to central control unit, described central control unit is converted into digital signal according to the image information that cmos image sensor transmits by the instruction of mobile device terminal and is transferred to the first wireless communication port, the digital signal transmission that central control unit transmits by the first wireless communication port is to portable mobile apparatus terminal, portable mobile apparatus terminal receives by the second wireless communication port digital signal that the first wireless communication port launches and by control unit, digital signal is converted into image information.
Preferably, described first wireless communication port is Bluetooth chip, accordingly, describedly portablely to move
Second wireless communication port of dynamic device end is bluetooth module.Second wireless communication port of described first wireless communication port and portable mobile apparatus terminal is by bluetooth approach communication.
Preferably, described first wireless communication port is WIFI chip, accordingly, describedly portablely to move
Second wireless communication port of dynamic device end is WIFI module.Second wireless communication port of described first wireless communication port and portable mobile apparatus terminal is by the communication of WIFI mode.
Preferably, described mobile device terminal is smart mobile phone.
Preferably, described mobile device terminal is notebook computer.
Described capsule endoscope also comprises capsule-like packaging shell, and described cmos image sensor, central control unit, the first wireless communication port and power supply are all encapsulated in described capsule-like housing.
The present invention also provides a kind of image information processing method, comprises the steps:
A () provides capsule endoscope detection system as claimed in claim 1, carry out digestive tract detection to sufferer, and detected image is sent to portable mobile apparatus terminal,
B the digestive tract image information that portable mobile apparatus terminal receives is carried out suspected lesion picture and is selected by (),
C suspected lesion picture that step (b) is selected by () meets at medical practitioner and diagnoses, and selects pathological changes picture.
Preferably, the screening personnel of described step (b) are non-medical background personnel.So not only can reduce the expense of whole inspection and the working time of doctor but also the work efficiency of doctor can have been improved.
Capsule endoscopy diagnosis system of the present invention, image information can be sent to the mobile device terminal such as smart mobile phone, notebook computer having and utilize bluetooth or WIFI function to carry out picture receiving function, overcome original drawback being concentrated reception process capsule endoscope image information by special-purpose computer work station, patient can carry out at home voluntarily, add the free mobility of patient, also can reduce the cost of manufacture of capsule, be convenient to this technology large-scale promotion and use.Realize the facilitation and the domestic that check capsule the most at last.The image information of capsule endoscope detection system of the present invention collection can first be carried out " self diagnostic mode ", namely patient carries out suspected lesion picture voluntarily and selects, again the suspected lesion picture filtered out is transferred to the further Screening Diagnosis of medical practitioner, the workload of doctor can be reduced so greatly, also can reduce inspection fee, improve the work efficiency of doctor.
Accompanying drawing explanation
The present invention is further illustrated to utilize accompanying drawing, but the content in accompanying drawing does not form any limitation of the invention.
Fig. 1 is the structured flowchart of capsule endoscope detection system of the present invention,
Fig. 2 is the flow chart of image information processing method of the present invention,
Fig. 3 is the palm picture of experimental model shooting,
Fig. 4 is ulcer pathological changes picture,
Fig. 5 is that flavochrome tumor becomes picture,
Fig. 6 is ulcer pathological changes picture.
Detailed description of the invention
The invention will be further described with the following Examples.
As shown in Figure 1, capsule endoscope detection system of the present invention, comprise capsule endoscope and portable mobile apparatus terminal, described capsule endoscope comprises cmos image sensor, central control unit, the first wireless communication port and power supply, and described mobile device terminal comprises the second wireless communication port and control unit, described power supply is cmos image sensor, central control unit and the first wireless communication port provide electric energy, described cmos image sensor gathers image information and image information is transferred to central control unit, described central control unit is converted into digital signal according to the image information that cmos image sensor transmits by the instruction of mobile device terminal and is transferred to the first wireless communication port, the digital signal transmission that central control unit transmits by the first wireless communication port is to portable mobile apparatus terminal, portable mobile apparatus terminal receives by the second wireless communication port digital signal that the first wireless communication port launches and by control unit, digital signal is converted into image information.Described cmos image sensor, central control unit, the first wireless communication port and power supply are all arranged in capsule-like housing.In the preferred embodiment, described first wireless communication port is Bluetooth chip, and described portable mobile apparatus terminal is the smart mobile phone of the Android system with wifi functional module and Bluetooth function module.In another preferred embodiment of the invention, described first wireless communication port is WIFI chip, described portable mobile apparatus terminal be have wifi functional module notebook computer.
As shown in Figure 2, image information processing method of the present invention comprises the digestive tract image utilizing the capsule endoscope of the WIFI of being provided with of the present invention or blue tooth interface (simultaneously formulating respective protocol) to gather patient, then upload in the domestic portable such as smart mobile phone or notebook computer mobile device terminal, then enable " volunteer's self diagnostic mode ", from 50,000 images once gathered, " self diagnosis " goes out 50 " the doubtful images of disease ", and then " the doubtful image of disease " is submitted to expert's (medical practitioner) diagnoses.
Below in conjunction with experiment, the present invention is further described.
experiment one
One, experimental model makes: form capsule endoscope structure with short-focus lens, lens mount, control circuit, battery, radiating circuit, antenna, magnetic switch and CMOS.Mobile device terminal selects the smart mobile phone with the Android system of WIFI and Bluetooth function.
Two, result, the collection of this model realization image and image are to the transmission of host computer.Existing capsule endoscope be all wirelessly picture collection to external image recorder, the image transmitting that imageing sensor collects by experimental model of the present invention shows to mobile device terminal, is beneficial to and carries and domestic.Fig. 3 is the picture of palm image transmitting to mobile phone of this experimental model collection.
Capsule endoscope detection system of the present invention, by realizing the facilitation and the domestic that check capsule, makes it to be popularized in a large number, then can break its " economical one ".In our experimental model, the price buying components and parts is respectively: photographic head 50 yuan, button cell 5 yuan, bluetooth module 30 yuan, singlechip chip 10 yuan.Add the expense of other accessory and encapsulation, estimated cost can control completely within 150 yuan.Namely check that the price of capsule can reduce about 13 times.And this item inspection total cost is estimated can control at about 200 yuan.Can predict, along with popularizing of Capsule Endoscopy, its Financial cost also can be impelled to reduce further.
test two image processing methods
One, experimentation
Utilize capsule endoscope of the present invention to check sufferer, we select whole pictures of some cases, it are given expert and volunteer to diagnose respectively.
Expert is Gastroenterology dept. capsule endoscope diagnostician 3 people.Expert need pick out the picture all having pathological changes for case, and provides diagnosis.
And volunteer is postgraduate 20 people without medical ground.We are supplied to volunteer's capsule endoscope diagnosis teaching material, simply learn 4 hours, the wherein collection of illustrative plates of the various model case of selective learning for it.Then we require that volunteer picks out the suspected lesion picture being less than 50 for each case, wherein think that the picture belonging to same focus only selects 1 representatively.The time that every volunteer selects suspected lesion picture according to case all images data is about 5 hours.
Experimental procedure: the picture collection display routine that (1) mobile phone development is relevant.What this experiment adopted is the image display program that Android develops;
(2) image that bluetooth capsule endoscope is taken is sent to mobile phone show and store,
The image that imageing sensor collects by bluetooth capsule endoscope transfers to external by the mode of Bluetooth transmission, and the mobile terminal with Bluetooth function receives, and shows and preserves,
(3) patient learns the relevant teaching material of capsule endoscopy diagnosis,
Relevant teaching material is the model case of the teaching material about capsule endoscope medical diagnosis on disease, selective learning disease,
(4) picture of suspected disease within 50 is found out by real-time monitored picture or the display picture be stored on mobile phone,
Volunteer checks the image collected by mobile device terminal, according to the study to (3), find out the picture of the suspected disease within 50,
(5) picture found out is submitted to doctor and do last diagnostic.
Two, experimental result
The whole pictures having 20 routine patients carry out diagnosis contrast:
Table one, diagnostic result contrast
Three. interpretation of result
Contrasted by the diagnosis of above 20 cases, we find:
Wherein case 4,5,6,10,11,16,18, volunteer finds out focus picture, does not occur undetected.
Wherein case 3 omits the picture mated with expert diagnosis (4), but does not affect last diagnostic, because the pathological changes detected is one species; Case 7,8,13,14,15,17,19 is also similar result.
Case 2 misses the picture matched with expert diagnosis (4), but this picture group sheet is uncertain class, and fixed identical type pathological changes is detected; Case 12 is similar.
Case 1 misses and the picture diagnosing (3) to mate, but does not affect last diagnostic, because the pathological changes kind apoplexy due to endogenous wind detected has included the kind identical with omitting focus.Case 9 is similar.
Case 20 does not find the picture of coupling, and wherein ulcer pathological changes picture is as Fig. 6.
We do a simple quantum chemical method to the result of above-mentioned 20 routine diagnostic tests.Wherein expert diagnosis has 86 focuses, and volunteer detects 53, omits 33, and namely Lesion Detection rate is 53/86=61%; Have 21 class diseases through expert diagnosis to plant, volunteer detects 20 kinds, and namely sick kind recall rate is 20/21=95.2%.
By above-mentioned experiment, we find: without the volunteer of medical ground, after simple exercise, can detect the disease kind of 95.2%.Although miss indivedual focus, these focuses are identical with the focus kind that same case has detected, do not affect last diagnostic.Further, volunteer leak select focus picture, likely specify with us select criterion about: the picture namely belonging to identical focus only selects 1 representatively picture.If the proper extension training time, improve and select criterion, and collect targetedly for the pathological changes of easily omitting and sum up, then quality of diagnosis is still expected to be promoted further, thus meets clinical needs completely.
Here it may be noted that, we are for the deficiency of existing capsule endoscope diagnostic mode, " self diagnostic mode " that proposed, its essence not substitutes medical practitioner by common person under inspection, but by after common person under inspection in addition simple exercise, picked out the suspected lesion picture (as being no more than 50) of some by it, do further diagnosis for doctor.Certainly, the case of inspection of will demanding perfection for the case of existing presumptive signs or patient oneself, can read whole picture by expert.The corresponding expense of this type of diagnosis can suitably improve.If this pattern is practicable words through fairly large experimental verification, so the diagnostic image quantity of doctor will reduce within 50 by about 50,000, thus its diagnosis efficiency can improve 1000 times in theory.
In China, the size of population is huge, the corresponding increase of doubtful sufferer sum.And along with carrying out of nine-year-system obligation system education and popularizing of higher education, the average schooling of people improves very fast.Add individual to the high attention rate of own health and high responsibility, the self diagnostic mode promoting capsule endoscope is necessitated and possibility.In fact, the pattern of checking oneself of disease early has carries out, and more successful example is adult female's checking oneself breast carcinoma.And under large data background, carry out the self diagnosis of capsule endoscope, perhaps can bring important promotion for carrying out this inspection, and bring useful inspiration for other similar research.
Experimentation of the present invention carries out suspected lesion picture by the volunteer without medical ground according to the capsule endoscope view data of magnanimity to select, and from 20 routine experimental results, sick recall rate of planting reaches more than 95%, and Lesion Detection rate reaches more than 60%.If strengthens training targetedly and improve picking rule further, and after more massive experimental verification, self diagnostic mode is expected to the important supplement as existing capsule endoscope clinical diagnosis pattern.Positive contribution will be had in assist physician diagnosis and endoscope are popularized.
Finally should be noted that; above embodiment is only in order to illustrate technical scheme of the present invention but not limiting the scope of the invention; although be explained in detail the present invention with reference to preferred embodiment; those of ordinary skill in the art is to be understood that; can modify to technical scheme of the present invention or equivalent replacement, and not depart from essence and the scope of technical solution of the present invention.
Claims (8)
1. a capsule endoscope detection system, it is characterized in that, comprise capsule endoscope and portable mobile apparatus terminal, described capsule endoscope comprises cmos image sensor, central control unit, the first wireless communication port and power supply, and described mobile device terminal comprises the second wireless communication port and control unit, described power supply is cmos image sensor, central control unit and the first wireless communication port provide electric energy, described cmos image sensor gathers image information and image information is transferred to central control unit, described central control unit is converted into digital signal according to the image information that cmos image sensor transmits by the instruction of mobile device terminal and is transferred to the first wireless communication port, the digital signal transmission that central control unit transmits by the first wireless communication port is to portable mobile apparatus terminal, portable mobile apparatus terminal receives by the second wireless communication port digital signal that the first wireless communication port launches and by control unit, digital signal is converted into image information.
2. capsule endoscope detection system as claimed in claim 1, is characterized in that, the second wireless communication port of described first wireless communication port and portable mobile apparatus terminal is by bluetooth approach communication.
3. capsule endoscope detection system as claimed in claim 1, is characterized in that, the second wireless communication port of described first wireless communication port and portable mobile apparatus terminal is by the communication of WIFI mode.
4. capsule endoscope detection system as claimed in claim 1, it is characterized in that, described mobile device terminal is smart mobile phone.
5. capsule endoscope detection system as claimed in claim 1, it is characterized in that, described mobile device terminal is notebook computer.
6. capsule endoscope detection system as claimed in claim 1, it is characterized in that, described capsule endoscope also comprises capsule-like packaging shell, and described cmos image sensor, central control unit, the first wireless communication port and power supply are all arranged in described capsule-like housing.
7. an image information processing method, is characterized in that, comprises the steps:
There is provided capsule endoscope detection system as claimed in claim 1, carry out digestive tract detection to sufferer, detected image is sent to portable mobile apparatus terminal,
The digestive tract image information that portable mobile apparatus terminal receives is carried out suspected lesion picture select,
Suspected lesion picture step (b) selected meets at medical practitioner and diagnoses, and selects pathological changes picture.
8. image information processing method as claimed in claim 7, it is characterized in that, the screening personnel of described step (b) are non-medical background personnel.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106389061A (en) * | 2015-08-10 | 2017-02-15 | 孙彪 | Vibration capsule system for recovering and treating digestive tract function degradation and disorder |
| CN110859596A (en) * | 2019-11-14 | 2020-03-06 | 大连理工大学 | Miniature gas-sensitive electronic capsule for detecting gas in human gastrointestinal tract |
| CN111462082A (en) * | 2020-03-31 | 2020-07-28 | 重庆金山医疗技术研究院有限公司 | Focus picture recognition device, method and equipment and readable storage medium |
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| US8098295B2 (en) * | 2006-03-06 | 2012-01-17 | Given Imaging Ltd. | In-vivo imaging system device and method with image stream construction using a raw images |
| CN103494595A (en) * | 2013-08-02 | 2014-01-08 | 南方医科大学南方医院 | Capsule endoscopy system |
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| CN1559337A (en) * | 2004-02-28 | 2005-01-05 | �����ɽ�Ƽ������ţ�����˾ | Radio capsule like endoscope system for medical use |
| US8098295B2 (en) * | 2006-03-06 | 2012-01-17 | Given Imaging Ltd. | In-vivo imaging system device and method with image stream construction using a raw images |
| CN103494595A (en) * | 2013-08-02 | 2014-01-08 | 南方医科大学南方医院 | Capsule endoscopy system |
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| CN106389061A (en) * | 2015-08-10 | 2017-02-15 | 孙彪 | Vibration capsule system for recovering and treating digestive tract function degradation and disorder |
| CN110859596A (en) * | 2019-11-14 | 2020-03-06 | 大连理工大学 | Miniature gas-sensitive electronic capsule for detecting gas in human gastrointestinal tract |
| CN111462082A (en) * | 2020-03-31 | 2020-07-28 | 重庆金山医疗技术研究院有限公司 | Focus picture recognition device, method and equipment and readable storage medium |
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