CN104415092A - Traditional Chinese medicine composition for treating breast hyperplasia and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating breast hyperplasia and preparation method thereof Download PDFInfo
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- CN104415092A CN104415092A CN201310364519.3A CN201310364519A CN104415092A CN 104415092 A CN104415092 A CN 104415092A CN 201310364519 A CN201310364519 A CN 201310364519A CN 104415092 A CN104415092 A CN 104415092A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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Abstract
The invention relates to a traditional Chinese medicine composition for treating breast hyperplasia and a preparation method thereof. The traditional Chinese medicine composition is a plaster which is prepared from following drugs: fennels, cinnamon, schizonepeta spike, divaricate saposhnikovia roots, semen brassicae, stiff silkworms, sesame oil, rosin and the like. The plaster is unique in formula, is definite in curative effects, is safe, economical and convenient, is free of significant toxic and side effects, has effects of regulating qi and resolving stasis, resolving phlegm and dissipating binds, and dispelling cold and relieving pain, and is suitable for patients suffered from the breast hyperplasia and dysmenorrhea in an externally-use adhesive manner.
Description
One, technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of cyclomastopathy and preparation method thereof, belong to biomedicine field.
Two, background technology
Cyclomastopathy is two large primary symptoms with breast portion lump and pain, belongs to mammary dysplasia pathological changes, mainly comprises Simple proliferation of mammary gland and cystic cyclomastopathy two kinds.Cyclomastopathy accounts for more than 70% of whole mastopathy, its morbidity peak age be 30-35 year, the women's sickness rate more than 30 years old reaches more than 90%, and its sickness rate accounts for the first place of cystic hyperplasia of breast.Because the primary disease course of disease is long, be easy to recurrence, the serious physical and mental health compromising women.Current pure Western medicine there is no desirable Therapeutic Method, and traditional Chinese medical herbal treatment cyclomastopathy has unique advantage and potential, from entirety, dialectically to combine with differential diagnosis of diseases, can from many aspects, multi-angle plays adjustment endocrine, the effect of enhancing human body immunity power, is the Therapeutic Method of clinical first-selection.
Cyclomastopathy belongs to categories such as the traditional Chinese medical science " infantile eczema " " nodules of the breast ".How because stagnation of QI due to depression of the liver, QI-blood circulation are smooth, passages through which vital energy circulates QI and blood blocks, depression of liver-QI, and Liver Channel QI and blood is smooth, qi depression to blood stasis, and blood stasis blocks passages through which vital energy circulates, stagnation of QI and blood may bring about pain, knot and be core.Breast carcinoma has another name called " breast carcinoma ", " milk rock ", " stone milk ", " Punica granatum L. sends out magic flower ", " mammary calculus " etc., be women's kinds of tumor.Southern Song Dynasty's Chen Ziming proposes the name of " breast carcinoma " first in " Complete Effective Prescriptions for Women ", and later age continues to use this more and says.This disease is called as in early days " (breast) stone carbuncle ", " carbuncle having to jail root and hard as stone person " (" Zhouhou Beiji Fang volume five "), how because of " the malicious stasis of expectorant ", with the passing of time diagenesis.Current each doctor to the etiology and pathogenesis that cyclomastopathy compares approval have hepatic depression it, the expectorant blood coagulation stasis of blood, Chong and Ren channel disorder, clinical each doctor emphasizes particularly on different fields.The utilization of external treatment in recent years, can make medicine be gone directly lesions position by Transdermal absorption, has fast, the eutherapeutic advantage of effect.
The present invention is on clinical experience basis, and found we with regulating the flow of QI to dissipate blood stasis, dissipating phlegm and resolving masses, cold-dispelling pain-relieving for method, be applicable to cyclomastopathy and dysmenorrhea patient external sticks, Clinical practice is achieved good results.The present invention adopts pure traditional Chinese medicine to form, have prescription uniqueness, determined curative effect, safety, economy, convenience, without features such as obvious toxic-side effects.
Three, summary of the invention
The object of the present invention is to provide a kind of determined curative effect, safety, economy, convenience, the Chinese medicine composition for the treatment of cyclomastopathy that has no side effect and preparation method thereof, be applicable to cyclomastopathy and dysmenorrhea patient external sticks.
The present invention program: a kind of Chinese medicine composition for the treatment of cyclomastopathy is made up of medicines such as Fructus Foeniculi, Cortex cinnamomi japonici (Ramulus Cinnamomi), Herba Schizonepetae, Radix Saposhnikoviae, Semen Sinapis Albae, Bombyx Batryticatus, Oleum Sesami, Colophonium, it is characterized in that the unguentum that following material composition and weight proportion are prepared from: 15 ~ 30 parts, Fructus Foeniculi, 10 ~ 20 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi), Herba Schizonepetae 10 ~ 20 parts, Radix Saposhnikoviae 10 ~ 20 parts, Semen Sinapis Albae 10 ~ 20 parts, Bombyx Batryticatus 10 ~ 20 parts, 100 ~ 300 parts, Oleum Sesami, Colophonium 30 ~ 60 parts.
A kind of preparation method for the treatment of the Chinese medicine composition of cyclomastopathy, it is characterized in that taking above each crude drug by recipe quantity, first Oleum Sesami is heated in little fire, successively Fructus Foeniculi, Cortex cinnamomi japonici (Ramulus Cinnamomi), Herba Schizonepetae, Radix Saposhnikoviae, Semen Sinapis Albae, Bombyx Batryticatus are added fried withered, 100 ~ 130 mesh sieves are excessively oily, be heated to 80 ~ 120 degree again, be dissolved in Colophonium fine powder and stir evenly, put in cold water to pull and pull out.Administrated method: get this cream by patient affected part size appropriate, stoking is placed on calico that size adapts to and is affixed on affected part, additional hot compress 10 minutes.Within 5 ~ 7 days, change dressings once.
The invention has the advantages that prescription uniqueness, determined curative effect, safety, economy, convenience, without obvious toxic-side effects, there is effect of regulating the flow of QI to dissipate blood stasis, dissipating phlegm and resolving masses, cold-dispelling pain-relieving, be applicable to cyclomastopathy and dysmenorrhea patient external sticks.
The routine cyclomastopathy patient of clinical treatment 80 of the present invention, achieves good results.
1, physical data: 80 routine female patients, 30 ~ 56 years old age, 43 years old mean age; The course of disease 3 weeks ~ 5 years; All cases all turn out to be cyclomastopathy through B ultrasonic, far infrared and/or aluminum target x-ray etc. inspections.
2, diagnostic criteria: the diagnostic criteria of formulating with reference to breast disease Professional Committee of Society of Surgery of China Association of Traditional Chinese Medicine in 2002: (1) side or bilateral distending pain of the breast or dull pain, during the moon premenstrual and anxious state of mind, pain is very; (2) one-sided or bilateral differs in size, and in the form of sheets, plate-like, graininess, streak, quality is pliable and tough, obscure boundary, with skin without adhesion, the lump in breast having tenderness; (3) mammary gland aluminum target x-ray is taken the photograph sheet and is seen that comparatively uniform density increases shadow.
3, Therapeutic Method: get this cream by patient affected part size appropriate, stoking is placed on calico that size adapts to and is affixed on affected part, additional hot compress 10 minutes.Within 5 ~ 7 days, changing dressings once, 7 days is 1 course for the treatment of.
4, criterion of therapeutical effect: the standard formulated with reference to the academic conference of national traditional Chinese medical science second time breast disease.(1) cure: lump disappears, mastalgia disappears, and stops treatment not recurring for 3 months; (2) effective: lump maximum gauge reduces > 1/2, mastalgia disappears; (3) effective: lump maximum gauge reduces < 1/2, and mastalgia alleviates; (4) invalid: lump is without reducing, and mastalgia is without alleviation.
5, therapeutic outcome: cure 36 examples, account for 45%; Effective 30 examples, account for 37.5%; Effective 10 examples, account for 12.5%; Invalid 4 examples, account for 5%, total effective rate 95%.Clinical observation has no toxic and side effects.
Clinical treatment 80 of the present invention routine cyclomastopathy patient curative effect situation
In addition, the present invention also has obvious curative effects to cold coagulation dysmenorrhea patient, and 23 routine dysmenorrhea patient clinical preruns show, total effective rate 95.65%.
Four, detailed description of the invention
With specific embodiment, the present invention is elaborated below:
Embodiment 1:
Raw material is taken: 12 parts, Fructus Foeniculi 20 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s, Herba Schizonepetae 12 parts, Radix Saposhnikoviae 12 parts, Semen Sinapis Albae 12 parts, Bombyx Batryticatus 12 parts, 130 parts, Oleum Sesami, Colophonium 40 parts according to following proportioning.
Preparation method: by recipe quantity by above each crude drug, first heats Oleum Sesami in little fire, adds fried withered successively by Fructus Foeniculi, Cortex cinnamomi japonici (Ramulus Cinnamomi), Herba Schizonepetae, Radix Saposhnikoviae, Semen Sinapis Albae, Bombyx Batryticatus, 110 mesh sieves are excessively oily, be heated to 100 degree again, be dissolved in Colophonium fine powder and stir evenly, put in cold water to pull and pull out.
Embodiment 2:
Raw material is taken: 25 parts, Fructus Foeniculi, 18 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi), Herba Schizonepetae 18 parts, Radix Saposhnikoviae 18 parts, Semen Sinapis Albae 18 parts, Bombyx Batryticatus 18 parts, 150 parts, Oleum Sesami, Colophonium 50 parts according to following proportioning.
Preparation method: by recipe quantity by above each crude drug, first heats Oleum Sesami in little fire, adds fried withered successively by Fructus Foeniculi, Cortex cinnamomi japonici (Ramulus Cinnamomi), Herba Schizonepetae, Radix Saposhnikoviae, Semen Sinapis Albae, Bombyx Batryticatus, 120 mesh sieves are excessively oily, be heated to 100 degree again, be dissolved in Colophonium fine powder and stir evenly, put in cold water to pull and pull out.
Embodiment 3:
Raw material is taken: 15 parts, Fructus Foeniculi, 15 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi), Herba Schizonepetae 15 parts, Radix Saposhnikoviae 15 parts, Semen Sinapis Albae 15 parts, Bombyx Batryticatus 15 parts, 200 parts, Oleum Sesami, Colophonium 35 parts according to following proportioning.
Preparation method: by recipe quantity by above each crude drug, first heats Oleum Sesami in little fire, adds fried withered successively by Fructus Foeniculi, Cortex cinnamomi japonici (Ramulus Cinnamomi), Herba Schizonepetae, Radix Saposhnikoviae, Semen Sinapis Albae, Bombyx Batryticatus, 120 mesh sieves are excessively oily, be heated to 100 degree again, be dissolved in Colophonium fine powder and stir evenly, put in cold water to pull and pull out.
Claims (3)
1. treat a Chinese medicine composition for cyclomastopathy, it is characterized in that the unguentum that following material composition and weight proportion are prepared from: 15 ~ 30 parts, Fructus Foeniculi, 10 ~ 20 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi), Herba Schizonepetae 10 ~ 20 parts, Radix Saposhnikoviae 10 ~ 20 parts, Semen Sinapis Albae 10 ~ 20 parts, Bombyx Batryticatus 10 ~ 20 parts, 100 ~ 300 parts, Oleum Sesami, Colophonium 30 ~ 60 parts.
2. a kind of Chinese medicine composition for the treatment of cyclomastopathy as claimed in claim 1, it is characterized in that preparation method: get 15 ~ 30 parts, Fructus Foeniculi, 10 ~ 20 parts, Cortex cinnamomi japonici (Ramulus Cinnamomi), Herba Schizonepetae 10 ~ 20 parts, Radix Saposhnikoviae 10 ~ 20 parts, Semen Sinapis Albae 10 ~ 20 parts, Bombyx Batryticatus 10 ~ 20 parts, 100 ~ 300 parts, Oleum Sesami, Colophonium 30 ~ 60 parts, first Oleum Sesami is heated in little fire, successively Fructus Foeniculi, Cortex cinnamomi japonici (Ramulus Cinnamomi), Herba Schizonepetae, Radix Saposhnikoviae, Semen Sinapis Albae, Bombyx Batryticatus are added fried withered, 100 ~ 130 mesh sieves are excessively oily, be heated to 80 ~ 120 degree again, be dissolved in Colophonium fine powder stirring evenly, put in cold water to pull and pull out.
3. a kind of application of Chinese medicine composition in preparation dysmenorrhea medicine for the treatment of cyclomastopathy as claimed in claim 1.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310364519.3A CN104415092B (en) | 2013-08-21 | 2013-08-21 | A kind of Chinese medicine composition and preparation method thereof for treating the proliferation of mammary gland |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310364519.3A CN104415092B (en) | 2013-08-21 | 2013-08-21 | A kind of Chinese medicine composition and preparation method thereof for treating the proliferation of mammary gland |
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| CN104415092A true CN104415092A (en) | 2015-03-18 |
| CN104415092B CN104415092B (en) | 2018-11-02 |
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| CN201310364519.3A Expired - Fee Related CN104415092B (en) | 2013-08-21 | 2013-08-21 | A kind of Chinese medicine composition and preparation method thereof for treating the proliferation of mammary gland |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003050267A2 (en) * | 2001-12-12 | 2003-06-19 | Credere Corporation | Method of isolating extract from the euphorbaciae obesa plant and methods for using the same |
| CN101185711A (en) * | 2006-11-15 | 2008-05-28 | 杨恩铭 | Nucleus eliminating ointment special for treating hyperplasia of mammary glands |
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- 2013-08-21 CN CN201310364519.3A patent/CN104415092B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003050267A2 (en) * | 2001-12-12 | 2003-06-19 | Credere Corporation | Method of isolating extract from the euphorbaciae obesa plant and methods for using the same |
| CN101185711A (en) * | 2006-11-15 | 2008-05-28 | 杨恩铭 | Nucleus eliminating ointment special for treating hyperplasia of mammary glands |
Non-Patent Citations (2)
| Title |
|---|
| 康广盛等: "《中医名方临床新用》", 31 October 2001 * |
| 张方胜: "《中华传世医方上 明医验方》", 31 May 1999 * |
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| CN104415092B (en) | 2018-11-02 |
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Granted publication date: 20181102 Termination date: 20200821 |