CN104414689A - Ultrasonic imaging method and ultrasonic imaging device for realizing high-sensitivity imaging - Google Patents

Ultrasonic imaging method and ultrasonic imaging device for realizing high-sensitivity imaging Download PDF

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CN104414689A
CN104414689A CN201310404746.4A CN201310404746A CN104414689A CN 104414689 A CN104414689 A CN 104414689A CN 201310404746 A CN201310404746 A CN 201310404746A CN 104414689 A CN104414689 A CN 104414689A
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mode
pattern
emitting voltage
view data
high sensitivity
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CN104414689B (en
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李雷
杨鹏飞
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Shenzhen Mindray Scientific Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/54Control of the diagnostic device
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06Measuring blood flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48Diagnostic techniques
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5207Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of raw data to produce diagnostic data, e.g. for generating an image
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01SRADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S15/00Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
    • G01S15/88Sonar systems specially adapted for specific applications
    • G01S15/89Sonar systems specially adapted for specific applications for mapping or imaging
    • G01S15/8906Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
    • G01S15/8979Combined Doppler and pulse-echo imaging systems
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01SRADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52019Details of transmitters
    • G01S7/5202Details of transmitters for pulse systems

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Remote Sensing (AREA)
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Abstract

The invention relates to an ultrasonic imaging method and an ultrasonic imaging device for realizing high-sensitivity imaging. The ultrasonic imaging method comprises the following steps of a normal imaging step, wherein an object to be detected is hybrid scanned for a couple of times, and each hybrid scanning comprises first mode scanning and second mode scanning; a high-sensitivity imaging step, wherein the transmitting voltage of second mode pulse is adjusted to be higher than the transmitting voltage of second mode pulse in the normal imaging step, and the transmitting voltage of first mode pulse is adjusted to be lower than the transmitting voltage of a first mode pulse signal in the normal imaging step. According to the embodiment of the invention, the high-sensitivity imaging step is added, so that the transmitting voltage of the second mode pulse is improved, the transmit voltage of the first mode pulse is reduced, and the sensitivity of imaging can be improved.

Description

Realize the ultrasonic imaging method of high sensitivity imaging, supersonic imaging device
Technical field
The present invention relates to ultra sonic imaging field, particularly relate to and a kind ofly realize the ultrasonic imaging method of high sensitivity imaging and a kind of supersonic imaging device.
Background technology
The propagation of medical ultrasound imaging equipment utilization ultrasound wave in human body, obtains the ultrasound wave characteristic information of tissue and organ structure.Usually many array element probe is adopted in supersonic imaging apparatus, high-voltage pulse ripple is carried in each array element of probe, excitation array element produces high-frequency ultrasonic and then forms launching beam and enters human body, to pop one's head in the echo of each array element recipient soma's structural scattering or reflection, form received beam, supersonic imaging apparatus extracts the information in ultrasonic echo, forms various imaging pattern and shows.The pulse that dissimilar imaging pattern is corresponding dissimilar, the corresponding B pulse of black and white imaging pattern (also claiming B-mode), color flow angiography pattern (also claiming C mode) corresponding C pulse etc.
Under C mode, calculated the multidate information of hemocyte in blood flow by Moveing target indication mode, according to the moving direction, speed, deployment conditions etc. of hemocyte, allocate red, blue, green three primary colours, change its brightness, be superimposed upon on two-dimensional scan image (i.e. Type B image).The design of current color flow angiography is generally the C pulse of alternate emission one frame and a frame B pulse, after launching and receiving, echo-signal is delivered to Beam synthesis resume module, improve the signal to noise ratio of echo-signal, again according to the character of echo-signal, the output signal of Beam synthesis is sent to corresponding signal processing module, namely relevantly to Type B image two-dimentional B signal processing module is sent to obtain two-dimentional Type B view data, relevant to colorful blood is sent to color Doppler flow signals processing module to obtain color blood-stream image data, finally, Type B view data and colorful blood data combine through display module, form the result data for display screen simultaneous display, as shown in Figure 1, in diagram, fan-shaped part is Type B image, be color blood-stream image in dotted line frame.
Generally, the intensity of picture signal and the intensity of echo-signal are directly proportional, and the intensity of echo-signal is then directly proportional with emitting voltage (because emitting voltage is directly proportional to the acoustic pressure of echo-signal).When the emission parameter such as transmitted waveform, transmitting aperture is fixing, emitting voltage determines the acoustic pressure of echo-signal, and emitting voltage determines detecting head surface temperature rise and acoustical power together with pulse recurrence frequency.But, the maximum of these emission parameters is all subject to International Electrotechnical Commission (IEC, International Electro-technical Commission), U.S. food and drug administration (FDA, Food and Drug Administration) etc. restriction, thus ultra sonic imaging quality is restricted.Sensitivity is most important performance indications in ultra sonic imaging quality, particularly in blood flow imaging.The factor the most directly having influence on sensitivity is emitting voltage, and it is generally by sound export-restriction.FDA define medical supersonic sound export indices, comprise Ispta.3(decay after spatial peak temporal average sound intensity), MI(mechanical index, Mechanical Index), TI(heat number, ThermalIndex).
For improving the sensitivity of ultra sonic imaging, some researchs adopt and improve the maximum voltage method of voltage to circuit instantaneously, but detecting head surface temperature rise can obviously increase in this case, exceedes the temperature that human body can bear.Meanwhile, mechanical index MI also can more than the secure threshold 6 of FDA suggestion.
IEC also specify the limitation standard of detecting head surface temperature rise.Such as, when under room temperature (being generally 23 ± 3 DEG C), probe contacts with apery soma body mould, pop one's head in for external, within 30 minutes, detecting head surface temperature rise is no more than 10 degree; For intervention probe, within 30 minutes, detecting head surface temperature rise is no more than 6 degree.For the probe (i.e. external probe) of topical application, IEC supposes that shell temperature is 33 degree, and add the maximum temperaturerise restriction of 10 degree, then the probe maximum surface temperature acting on body surface must not more than 43 degree; For intervention probe, IEC supposition is 37 degree with the contact surface initial temperature of probe, and add the maximum temperaturerise restriction of 6 degree, the maximum surface temperature getting involved probe also must not be more than 43 degree.IEC also specify at room temperature, and in static air, detecting head surface temperature rise is no more than 27 degree.
Because B-mode is generally that transmitted pulse is shorter, emitting voltage is larger, therefore mechanical index MI is the principal element of restriction emitted energy, and C mode is generally that transmitted pulse is longer, emitting voltage is less, therefore detecting head surface temperature rise is the principal element of restriction emitted energy, and its mechanical index MI does not reach the upper limit threshold of FDA.To this, for improving the sensitivity of blood flow imaging, existing research proposal mounting temperature sensor on probe, the transmitting power of probe is controlled by temperature sensor, after probe temperature exceedes a certain condition, automatic adjustment emission parameter, as pulse recurrence frequency, frequency, emitting voltage etc., thus maintains surface temperature of probe in a certain tolerance interval.But although temperature sensor can effectively detect and control surface temperature of probe, there are the following problems: on the one hand, badly cannot predict in advance during picture quality fashion, cause affecting the expection of diagnostician to probe map picture; On the other hand, mounting temperature sensor on probe, adds the cost of probe virtually, complexity and the probability broken down.
Summary of the invention
The invention provides and a kind ofly can realize the ultrasonic imaging method of high sensitivity blood flow imaging and the supersonic imaging device of correspondence thereof.
According to a first aspect of the invention, the invention provides a kind of ultrasonic imaging method realizing high sensitivity imaging, it is characterized in that, comprise: normal imaging step, described normal imaging step comprises: the first emitting voltage launches first mode pulse signal to object to be detected in a first pattern, receive first mode first ultrasound echo signal returned from described object to be detected, process to obtain first mode first view data to described first mode first ultrasound echo signal; First emitting voltage launches the second patterned pulse signal to described object to be detected in a second mode, receive the second pattern first ultrasound echo signal returned from described object to be detected, process to obtain the second pattern first view data to described second pattern first ultrasound echo signal; Show described first mode first view data and described second pattern first view data; After receiving the triggering signal entering high sensitivity image-forming step, perform high sensitivity image-forming step, described high sensitivity image-forming step comprises: the second emitting voltage launches first mode pulse signal to described object to be detected in a first pattern, receive first mode second ultrasound echo signal returned from described object to be detected, process to obtain first mode second view data to described first mode second ultrasound echo signal; Second emitting voltage launches the second patterned pulse signal to described object to be detected in a second mode, receive the second pattern second ultrasound echo signal returned from described object to be detected, process to obtain the second pattern second view data to described second pattern second ultrasound echo signal; Show described first mode second view data and described second pattern second view data; Wherein said second pattern second emitting voltage is higher than described second pattern first emitting voltage, and described first mode second emitting voltage is lower than described first mode first emitting voltage.
In one embodiment of the present of invention, also comprise: recover normal imaging step, after described high sensitivity image-forming step continues the first Preset Time, recover to perform described normal imaging step.
In one embodiment of the present of invention, also comprise: described high sensitivity image-forming step reverts in the default out-of-service time after described normal imaging step, described high sensitivity image-forming step is prohibited to trigger.
In one embodiment of the present of invention, described second pattern second emitting voltage meets the criterion that in medical supersonic, sound exports.
In one embodiment of the present of invention, described first Preset Time and described default out-of-service time meet: make when supersonic imaging device switches back and forth between described high sensitivity image-forming step and described normal imaging step, the surface temperature rise of ultrasonic probe meets the limitation standard of detecting head surface temperature rise in medical supersonic.
In one embodiment of the present of invention, described first Preset Time is longer, and the voltage amplitude that described second pattern second emitting voltage improves relative to described second pattern first voltage is less.
In one embodiment of the present of invention, described first mode second emitting voltage is zero, and wherein reads described first mode first view data as described first mode second view data.
In one embodiment of the present of invention, described first mode is B-mode, M-mode and/or D mode.
In one embodiment of the present of invention, described second pattern is C mode and/or D mode.
According to a further aspect in the invention, additionally provide a kind of supersonic imaging device, it is characterized in that, comprising: ultrasonic probe; Transmitter module, described transmitter module is used in normal imaging step, first emitting voltage launches first mode pulse signal by described ultrasonic probe to object to be detected in a first pattern, and the first emitting voltage launches the second patterned pulse signal by described ultrasonic probe to object to be detected in a second mode; And in high sensitivity image-forming step, second emitting voltage launches first mode pulse signal by described ultrasonic probe to described object to be detected in a first pattern, and the second emitting voltage launches the second patterned pulse signal by described ultrasonic probe to object to be detected in a second mode; Voltage control module, described voltage control module is used in normal imaging step, and the emitting voltage controlling described transmitter module is described first mode first emitting voltage or described second pattern first emitting voltage; And for after receiving the triggering signal entering high sensitivity image-forming step, the emitting voltage controlling described transmitter module changes described first mode second emitting voltage or described second pattern second emitting voltage into; Receiver module, described receiver module is used in normal imaging step, receives first mode first ultrasound echo signal returned from described object to be detected and the second pattern first ultrasound echo signal returned from described object to be detected; And in high sensitivity image-forming step, receive first mode second ultrasound echo signal returned from described object to be detected and the second pattern second ultrasound echo signal returned from described object to be detected; Signal processing module, described signal processing module is used in normal imaging step, processes to obtain first mode first view data and process to obtain the second pattern first view data to described second pattern first ultrasound echo signal to described first mode first ultrasound echo signal; And in high sensitivity image-forming step, process to obtain first mode second view data and process to obtain the second pattern second view data to described second pattern second ultrasound echo signal to described first mode second ultrasound echo signal; Display module, for showing described first mode first view data and described second pattern first view data or showing described first mode second view data and described second pattern second view data; Wherein said second pattern second emitting voltage is higher than described second pattern first emitting voltage, and described first mode second emitting voltage is lower than described first mode first emitting voltage.
In one embodiment of the present of invention, described voltage control module is after described high sensitivity image-forming step continues the first Preset Time, and the emitting voltage controlling described transmitter module reverts to described first mode first emitting voltage or described second pattern first emitting voltage.
In one embodiment of the present of invention, in the default out-of-service time after the emitting voltage of described transmitter module reverts to described first mode first emitting voltage or described second pattern first emitting voltage, forbid triggering described high sensitivity image-forming step.
In one embodiment of the present of invention, described first Preset Time and described default out-of-service time meet: make when supersonic imaging device switches back and forth between described high sensitivity image-forming step and described normal imaging step, the surface temperature rise of ultrasonic probe meets the limitation standard of detecting head surface temperature rise in medical supersonic.
The invention has the beneficial effects as follows: due to the triggering of high sensitivity image-forming step, the emitting voltage of the second patterned pulse signal is improved and the emitting voltage of first mode pulse reduces, improve the sensitivity of blood flow imaging, also reduce the speed of detecting head surface temperature rise., the run duration of high sensitivity image-forming step is limited meanwhile, further avoid sound output-index and surface temperature rise exceeds restriction.Like this, achieve and both meet the requirement of FDA and IEC relevant laws and regulations, also there is higher image sensitivity (such as, blood flow imaging sensitivity).
Accompanying drawing explanation
Fig. 1 is the schematic diagram of the result of two dimensional image and blood-stream image combination display;
Fig. 2 is the schematic diagram of the supersonic imaging device of an embodiment of the present invention;
Fig. 3 is the voltage-controlled schematic diagram in an embodiment of the present invention under normal imaging step;
Fig. 4 is the structured flowchart of the supersonic imaging device of an embodiment of the present invention;
Fig. 5 is the voltage-controlled schematic diagram in an embodiment of the present invention under high sensitivity image-forming step;
Fig. 6 is the Control of Voltage time diagram in an embodiment of the present invention under high sensitivity image-forming step;
Fig. 7 is the temperature rise control schematic diagram in an embodiment of the present invention under high sensitivity image-forming step;
Fig. 8 is the Control of Voltage time diagram in the another kind of embodiment of the present invention under high sensitivity image-forming step.
Detailed description of the invention
In various embodiments of the present invention, at guarantee sound output-index MI, Ispta.3, TI meets FDA laws and regulations requirement, under detecting head surface temperature rise meets the prerequisite of IEC laws and regulations requirement, within specific sweep time, suitable reduction first mode emitted energy, improve the second Mode Launch energy, thus improve the sensitivity of supersonic blood imaging, after this scan method continues for some time, system automatically switches to normal scan, retrain user simultaneously and again can not enter this specific scan mode within a certain period of time, thus ensure that sound output-index and detecting head surface temperature rise meet the laws and regulations requirement of FDA and IEC all the time.
First some terms itself please used in each embodiment or concept are made an explanation.
(1) normal imaging step: refer to the imaging image-forming step that ordinary ultrasonic imaging adopts often, during normal work, supersonic imaging device can use one or more imaging patterns to carry out imaging, such as, first mode can be used (such as, B-mode, M-mode and/or D mode etc.) and the second pattern (such as, C mode and/or D mode etc.) carry out imaging.In the present invention's embodiment hereinafter, be that example is described for B-mode, the second pattern are C mode in a first pattern.But, one of ordinary skill in the art will readily recognize that first mode here and the second pattern also can be any imaging patterns that other is applicable to.
The various imaging patterns (B-mode, C mode, M-mode, D mode etc.) mentioned herein refer to and the ultrasound imaging mode known by those skilled in the art of the present invention no longer specifically describe at this in detail.
In each imaging pattern, the transmitter module of supersonic imaging device launches pulse signal corresponding to this imaging pattern with certain emitting voltage to object to be detected by ultrasonic probe.Such as, aforesaid first mode be B-mode, the second pattern is in the example of C mode, the transmitted pulse under first mode (B-mode) is shorter, emitting voltage is comparatively large, and transmitted pulse under the second pattern (C mode) is longer, emitting voltage is less., the emitting voltage of first mode in normal imaging step is called first mode first emitting voltage herein, similarly, the emitting voltage of the second pattern in normal imaging step is called the second pattern first emitting voltage.
(2) high sensitivity image-forming step: refer to improve the image-forming step that ultra sonic imaging sensitivity (such as, blood flow imaging sensitivity) is major consideration (or main purpose).Similarly, in high sensitivity image-forming step, under each imaging pattern, the transmitter module of supersonic imaging device also launches pulse signal corresponding to this imaging pattern with certain emitting voltage to object to be detected by ultrasonic probe., the emitting voltage of first mode in high sensitivity image-forming step is called first mode second emitting voltage herein, similarly, the emitting voltage of the second pattern in high sensitivity image-forming step is called the second pattern second emitting voltage.。
By reference to the accompanying drawings the present invention is described in further detail below by detailed description of the invention.
Embodiment 1:
The present embodiment provides a kind of supersonic imaging device, as shown in Figure 2, comprising: voltage control module 20, transmitter module 21, ultrasonic probe 22, receiver module 23, signal processing module 24 and display module 25.The array element that the exomonental shape of Systematical control and participation are launched, the emitting voltage of each imaging pattern is controlled respectively by voltage control module 20, ultrasonic probe 22 is acoustical signal the transform electrical signals of excitation, is transmitted into object to be detected (such as, tissue).The ultrasonic echo of object reflection to be detected receives through each array element of ultrasonic probe and converts the signal of telecommunication to, forms ultrasound echo signal (ultrasound echo signal).Receiver module 23 receives these ultrasound echo signals (ultrasound echo signal) and processes accordingly, then these ultrasound echo signals carry out process by signal processing module 24 and form ultrasound image data, and the ultrasound image data of formation is shown finally by display module 25.
In embodiments of the invention, although ultrasound echo signal refers to the signal of telecommunication, and what return from object to be detected is acoustical signal (ultrasonic echo), but ultrasound echo signal is obtained by the ultrasonic echo returned from object to be detected, this ultrasound echo signal is therefore still claimed to be the ultrasound echo signal of " returning from object to be detected " herein.
Similarly, although transmitter module 21 launches acoustical signal (ultrasound wave) to make array element to object to be detected with the array element of the electric pulse of pulse signal form excitation ultrasonic probe in embodiments of the invention, what that is in fact launch to object to be detected is acoustical signal, but because these acoustical signals encourage generation by pulse signal, because be still referred to as herein " to object transmitted pulse signal to be detected ", such as, " to object transmitting first mode pulse signal to be detected ", " launching the second patterned pulse signal to object to be detected " etc.That is, referring to object transmitted pulse signal to be detected of mentioning herein makes array element launch ultrasound wave to object to be detected with the array element of pulse signal excitation ultrasonic probe.
Based on the ultrasonic imaging method of the high sensitivity blood flow imaging that this supersonic imaging device realizes, comprise the steps.
Normal imaging step, this normal imaging step can comprise two kinds of imaging patterns (such as, first mode and the second pattern), and its concrete steps can be as described below.
In first mode, the emitting voltage that voltage control module 20 controls transmitter module 21 is first mode first emitting voltage, transmitter module 21 in a first pattern the first emitting voltage launches first mode pulse signal by ultrasonic probe 22 to object to be detected, receiver module 23 receives first mode first ultrasound echo signal returned from object to be detected, and signal processing module 24 pairs of first mode first ultrasound echo signals process to obtain first mode first view data.
In second pattern, the emitting voltage that voltage control module 20 controls transmitter module 21 is the second pattern first emitting voltage, transmitter module 21 in a second mode the first emitting voltage launches the second patterned pulse signal by ultrasonic probe 22 to object to be detected, receiver module 23 receives the second pattern first ultrasound echo signal returned from object to be detected, and signal processing module 24 processes to obtain the second pattern first view data to the second pattern first ultrasound echo signal.
In embodiments of the invention, first mode imaging (or first mode scanning) and the second mode imaging (or second Mode scans) can hocket.Such as, can first carry out one or more first mode line sweep, then carry out the scanning of one or more second mode line, then carry out one or more first mode line sweep, then carry out the scanning of one or more second mode line, by that analogy.Here, " line sweep " refers in ultra sonic imaging as obtaining the scanning that a scan-line data carries out.
In embodiments of the invention, also can be first carry out one or more first mode frame scan, then carry out the scanning of one or more second model frame, then carry out one or more first mode frame scan, carry out the scanning of one or more second model frame again, by that analogy.Here, " frame scan " refer in ultra sonic imaging as obtaining the scanning that a frame image data carries out.
By above-mentioned normal imaging step, the view data under first mode and the second pattern can be obtained, be referred to as first mode first view data and the second pattern first view data herein.Then, display module 25 can show first mode first view data (such as, B-mode view data) and the second pattern first view data (such as, C mode view data) that obtain in abovementioned steps.
Transmitted waveform and the voltage of first mode scanning and the second Mode scans normally carry out independent control respectively, as shown in Figure 3, if the emitting voltage of first mode scanning and the second Mode scans is respectively VB and VC, under normal imaging step, first mode scanning can select shorter transmitted pulse and higher emitting voltage, and the second Mode scans can select longer transmitted pulse and lower emitting voltage.
Ultrasonic signal enters human body, after the physical processes such as a series of reflection, scattering and refraction, portion of energy returns transducer, now in receiver module, system is switched to accepting state by such as high-voltage switch gear, the each array element of transducer receives ultrasonic echo and is converted into the signal of telecommunication (such as, aforesaid first mode first ultrasound echo signal and the second pattern first ultrasound echo signal), and these signals of telecommunication are received by receiver module 23 and process accordingly.
Receiver module 23 and signal processing module 24 can adopt conventional ultrasound echo signal process and Display Technique to process ultrasound echo signal.Such as, first the ultrasound echo signal of reception is converted to the signal of telecommunication, then this signal of telecommunication is through simulated time gain compensation (ATGC, Analog Time Gain Compensation) to compensate the ultrasonic attenuation under different depth, after carrying out analog digital conversion, analog echo signal is converted to digital ultrasound echo-signal and is then sent to Beam synthesis module, Beam synthesis module calculates the time delay of each array element echo-signal of control by time delay and carries out apodization, to improve the signal to noise ratio of current received scanline echo-signal.Then, relevant to the first mode imaging first mode signal processing link that enters is carried out envelope detected etc. and is processed to obtain first mode first view data; Relevant to the second mode imaging enters the second mode signal processing links.Such as, second pattern is in the embodiment of C mode, the second pattern first ultrasound echo signal after Beam synthesis by wall filtering process with the strong tissue echo signal in filtered signal, then enter blood flow parameter estimation module to obtain current blood flow rate, variance and energy, blood flow post-processing module carries out the operations such as frame is relevant, level and smooth to improve blood flow form to the blood flow information estimated subsequently; Finally, first mode first view data (such as, two-dimensional image data) and blood-stream image data (i.e. the second pattern first view data), through display module combination, form the result data for display screen simultaneous display, as shown in Figure 4.ATGC mentioned here, Beam synthesis, quadrature demodulation, envelope detected, wall filtering, blood flow parameter is estimated, frame is relevant, level and smooth, display etc. can adopt technology well-known to those skilled in the art, does not elaborate at this.
After receiving the triggering signal entering high sensitivity image-forming step, enter high sensitivity image-forming step, correspondingly this high sensitivity image-forming step also comprises two kinds of imaging patterns (such as, first mode and the second pattern), and its concrete steps can be as described below.
In a first mode, the emitting voltage that voltage control module 20 controls transmitter module 21 changes first mode second emitting voltage into, transmitter module 21 in a first pattern the second emitting voltage launches first mode pulse signal to object to be detected, receiver module 23 receives first mode second ultrasound echo signal returned from object to be detected, and signal processing module 24 pairs of first mode second ultrasound echo signals process to obtain first mode second view data.
In a second mode, the emitting voltage that voltage control module 20 controls transmitter module 21 changes the second pattern second emitting voltage into, transmitter module 21 in a second mode the second emitting voltage launches the second patterned pulse signal to object to be detected, receiver module 23 receives the second pattern second ultrasound echo signal returned from object to be detected, and signal processing module 24 processes to obtain the second pattern second view data to the second pattern second ultrasound echo signal.
Similar with aforesaid normal imaging step, in high sensitivity image-forming step, first mode imaging (or first mode scanning) and the second mode imaging (or second Mode scans) also can hocket.Such as, in an embodiment, can first carry out one or more first mode line sweep, then the scanning of one or more second mode line is carried out, carry out one or more first mode line sweep again, then carry out the scanning of one or more second mode line, by that analogy.Here, " line sweep " refers in ultra sonic imaging as obtaining the scanning that a scan-line data carries out.Or, in other embodiment, also can be first carry out one or more first mode frame scan, then the scanning of one or more second model frame is carried out, carry out one or more first mode frame scan again, then carry out the scanning of one or more second model frame, by that analogy.Here, " frame scan " refer in ultra sonic imaging as obtaining the scanning that a frame image data carries out.
In embodiments of the invention, aforesaid second pattern second emitting voltage is higher than the second pattern first emitting voltage, and first mode second emitting voltage is lower than described first mode first emitting voltage.
In embodiments of the invention, aforesaid first mode first emitting voltage and the second pattern first emitting voltage can be mutually different.Aforesaid first mode second emitting voltage and the second pattern second emitting voltage also can be mutually different.
In this high sensitivity image-forming step, after obtaining first mode second view data and the second pattern second view data, display module 25 can show this first mode second view data (such as, B-mode image) and the second pattern second view data (such as, C mode image).
For this high sensitivity image-forming step, exomonental power supply supply can as shown in Figure 5, and the second Mode scans can select longer transmitted pulse and higher transmit voltage, and first mode scanning can select shorter transmitted pulse and lower emitting voltage.In embodiments of the invention, second pattern can be for the higher imaging pattern of image sensitivity requirement (such as, C mode), in this high sensitivity image-forming step step, second pattern employs higher emitting voltage, and first mode employs lower emitting voltage, therefore improve the sensitivity of imaging (such as, blood flow imaging).
The triggering signal entering high sensitivity image-forming step can manually be selected high sensitivity imaging pattern by input equipment (as trace ball or touch screen or mouse etc.) by operator and produce (such as selecting after normal imaging step continuous firing at least the second Preset Time) in supersonic imaging device, should be understood that in supersonic imaging device now and high sensitivity imaging option is provided.In other embodiments, the triggering signal entering high sensitivity image-forming step can be automatically produced after normal imaging step continuous firing second Preset Time by supersonic imaging device, such as, arrange enumerator in supersonic imaging device to count normal image-forming step, when arriving predetermined count value (being also predetermined time), produce the triggering signal of high sensitivity image-forming step, etc.That is, after normal imaging step continuous firing a period of time (as the second preset time t 2), high sensitivity image-forming step is automatically switched to.After high sensitivity image-forming step triggers, the maximum restriction of the MI that the instantaneous FDA of bringing up to of emitting voltage VC of the second Mode scans specify, meet the criterion of sound output in medical supersonic, the sensitivity of blood flow imaging increases.
In embodiments of the invention, can also comprise and recover normal imaging step, namely after high sensitivity image-forming step continues the first preset time t 1, normal imaging step can be reverted to.Now, this recovery normal imaging step can revert to aforesaid first mode first emitting voltage (in first mode) or the second pattern first emitting voltage (in the second pattern) by voltage control module 20 at the emitting voltage that high sensitivity image-forming step continues to control after the first preset time t 1 transmitter module 21 and realize.
In embodiments of the invention, can also, in the default out-of-service time after high sensitivity image-forming step reverts to normal imaging step, forbid triggering high sensitivity image-forming step.Here, forbid triggering high sensitivity image-forming step and can produce high sensitivity image-forming step triggering signal by forbidding user or ultrasonic image-forming system and/or by forbidding that voltage control module 20 changes the emitting voltage of transmitter module 21 into first mode second emitting voltage or the second pattern second emitting voltage or any mode that other is applicable to and realizes.
In embodiments of the invention, high sensitivity image-forming step and the normal imaging step of supersonic imaging device can switch back and forth.In high sensitivity image-forming step, the emitting voltage of the second pattern is enhanced, thus improves the sensitivity of imaging (such as, blood flow imaging).Meanwhile, by controlling the persistent period of high sensitivity image-forming step and forbidding triggering the default out-of-service time of high sensitivity image-forming step, the system temperature of supersonic imaging device can be ensured and not obvious rising, be no more than the regulation restriction of IEC.That is, aforesaid first Preset Time and default out-of-service time meet: make when supersonic imaging device switches back and forth at high sensitivity image-forming step and normal imaging step, the surface temperature rise of ultrasonic probe meets the limitation standard of detecting head surface temperature rise in medical supersonic.
Here, high sensitivity image-forming step persistent period with forbid that the concrete value of the default out-of-service time of triggering high sensitivity image-forming step can be determined according to relevant character of the heat of the material of the concrete magnitude of voltage of probe under each pattern or power, radiating condition, probe and probe material etc.The concrete defining method of the concrete value of this persistent period and default out-of-service time can be any applicable method, such as, then multi-group data obtains persistent period and/or default out-of-service time and detecting head surface temperature rise functional relationship according to statistics, matching, analysis etc. the method for these experimental datas can be measured by experiment, thus determine the persistent period of correspondence under certain concrete condition and/or default out-of-service time according to this functional relationship; Or obtain persistent period under specified conditions and/or default out-of-service time according to the derive functional relationship that obtains persistent period and/or default out-of-service time and detecting head surface temperature rise or the direct derivation of the formula of hot relevant nature of probe material, radiating condition formula and/or voltage or the functional relationship between power and caloric value etc.; Etc..The concrete steps of these experiments, Data Processing in Experiment and/or derivation method can be well known to those skilled in the art, do not repeat them here.
In the embodiment of the present invention, under multiplex's emission state, make normal imaging step enter high sensitivity image-forming step, and under high sensitivity image-forming step, improve the emitting voltage of the second mode pulse, the emitting voltage of reduction first mode pulse, and due to the raising of the second mode pulse emitting voltage, thus the sensitivity of imaging can be made to be improved, and due to the reduction of first mode impulse ejection voltage and the switching of imaging pattern, for ensure supersonic imaging device system temperature and not obvious rising provides possibility.
Embodiment 2:
The difference of the present embodiment and embodiment 1 is: to the restriction of the second mode pulse emitting voltage improved in high sensitivity image-forming step (i.e. aforesaid second pattern second voltage).Now, the concrete scanning process that the transmitter module of the present embodiment or step of transmitting relate to as shown in Figure 6, under normal imaging step, the running voltage of the second Mode scans is less, after high sensitivity image-forming step triggers, the maximum restriction of the MI that the instantaneous FDA of bringing up to of emitting voltage VC of the second Mode scans specifies, meet the criterion that in medical supersonic, sound exports, the emitting voltage VB of first mode scanning then correspondingly reduces, after this high sensitivity image-forming step continuous firing first preset time t 1, automatically switch to normal imaging step, normal imaging step continuous firing second preset time t 2, ensure the system temperature of supersonic imaging device as much as possible and not obvious rising, be no more than the regulation restriction of IEC.Based on this, the Adjustment principle of the first preset time t 1 is: if the first Preset Time is longer, then the voltage amplitude that is enhanced of the emitting voltage of the second mode pulse is less, and that is the voltage amplitude that improves relative to the second pattern first voltage of aforesaid second pattern second emitting voltage is less.
Embodiment 3:
Based on embodiment 1, in the present embodiment, after switching back normal imaging step from high sensitivity image-forming step, normal imaging step continuous firing a period of time (as the second preset time t 2), the second Preset Time is more than or equal to the default out-of-service time.When realizing, t1 and t2 is defined as: supersonic imaging device adopts high sensitivity image-forming step and normal imaging step, and switch operating several (t1+t2) is after the time back and forth, and the surface temperature rise of ultrasonic probe meets the limitation standard about detecting head surface temperature rise in medical supersonic.Thus can ensure that supersonic imaging device there will not be because continuous firing is in the situation of higher transmit energy, finally ensure that within all working time, detecting head surface temperature rise all can not more than the laws and regulations requirement of IEC.
IEC is defined in any case, all must not more than 43 degree in the temperature of detecting head surface half an hour after system starts.The present embodiment meets the prerequisite of the requirement of MI and Ispta.3 that FDA specifies at emitting voltage under, by controlling the persistent period t1 of high sensitivity image-forming step and switching back the out-of-service time after normal imaging step, even if ensure user continue low between high sensitivity image-forming step and this two states of normal imaging step repeatedly switch reach halfhour extreme working position under, detecting head surface temperature rise still meets IEC laws and regulations requirement.Similar with embodiment 2, if the principle that the t1 persistent period adjusts is that the persistent period is elongated, then the corresponding emitting voltage step-down of the second pattern, surface temperature of probe T changes and the variation relation of change t in time of voltage VB, VC can be as shown in Figure 7.
Embodiment 4:
Owing to adopting high sensitivity image-forming step in previous embodiment 1-3, the emitting voltage of first mode pulse is reduced, first mode view data may be made to weaken to some extent, based on this, the present embodiment makes improvements foregoing embodiments, namely, when to the echo signal processing received, by automatic gain compensation method, first mode brightness of image is compensated.Here the method for automatic gain compensation can realize with reference to the correlation technique in conventional Digital Image Processing, such as the first mode view data obtained is carried out to the image enhancement processing etc. of the gray feature based on pixel, said gray feature includes but not limited to grey level histogram, gray average, gray variance, shade of gray etc.Thus, adopt the ultrasonic imaging method of the present embodiment can not only improve the sensitivity of blood flow imaging, and the quality of first mode image is also unaffected.
Embodiment 5:
The difference of the present embodiment and previous embodiment is, when being in high sensitivity image-forming step, stop first mode scanning, namely the transmitting of first mode pulse signal is directly closed, the emitting voltage of first mode pulse signal is zero, as shown in Figure 8, thus the emitting voltage of the second higher patterned pulse signal can be obtained, improve image sensitivity; And first mode view data and the second mode image data are being synthesized so that before display, here for the synthesis of the first mode view data (i.e. first mode first view data) in the normal imaging step of buffer memory before first mode view data (the i.e. first mode second view data) employing shown, the first mode view data namely before employing triggering high sensitivity image-forming step is as first mode view data during high sensitivity image-forming step.That is, aforesaid first mode first view data is read as first mode second view data (easy understand, now first mode first view data is identical with first mode second view data) here.Thus, adopt the ultrasonic imaging method of the present embodiment can not only improve the sensitivity of blood flow imaging, and the quality of first mode view data is also unaffected.
In each embodiment aforesaid, although be that example is illustrated for B-mode, the second pattern are C mode in a first pattern, in embodiments of the invention, " first mode " wherein and " the second pattern " can be any applicable ultrasound imaging mode respectively.Especially, the second pattern can be for the higher imaging pattern (such as, for the C mode of blood flow imaging) of image sensitivity requirement.Such as, first mode can be B-mode, M-mode and/or D mode etc., and the second pattern can be C mode and/or D mode etc.
From foregoing teachings, in embodiments of the invention, provide a kind of supersonic imaging device.This supersonic imaging device comprises voltage control module 20, transmitter module 21, ultrasonic probe (also known as probe) 22, receiver module 23, signal processing module 24 and display module 25.
Transmitter module 21 is in normal imaging step, first emitting voltage launches first mode pulse signal by ultrasonic probe 22 to object to be detected in a first pattern, and the first emitting voltage launches the second patterned pulse signal by 22 ultrasonic probes to object to be detected in a second mode; And in high sensitivity image-forming step, second emitting voltage launches first mode pulse signal by ultrasonic probe 22 to object to be detected in a first pattern, and the second emitting voltage launches the second patterned pulse signal by ultrasonic probe 22 to object to be detected in a second mode.
Voltage control module 20 is in normal imaging step, and the emitting voltage controlling transmitter module 21 is first mode first emitting voltage or the second pattern first emitting voltage; And for after receiving the triggering signal entering high sensitivity image-forming step, the emitting voltage controlling transmitter module 21 changes first mode second emitting voltage or the second pattern second emitting voltage into.
Receiver module 23, in normal imaging step, receives first mode first ultrasound echo signal (the first mode pulse signal launched under first mode first emitting voltage by object reflection to be detected and obtain) returned from object to be detected and the second pattern first ultrasound echo signal returned from object to be detected (second patterned pulse signal of being launched under the second pattern first emitting voltage by object reflection to be detected and obtain); And in high sensitivity image-forming step, receive first mode second ultrasound echo signal (the first mode pulse signal launched at first mode second emitting voltage by object reflection to be detected and obtain) returned from object to be detected and the second pattern second ultrasound echo signal returned from object to be detected (second patterned pulse signal of being launched under the second pattern second emitting voltage by object reflection to be detected and obtain).
Signal processing module 24, in normal imaging step, processes to obtain first mode first view data and process to obtain the second pattern first view data to the second pattern first ultrasound echo signal to first mode first ultrasound echo signal; And in high sensitivity image-forming step, process to obtain first mode second view data and process to obtain the second pattern second view data to the second pattern second ultrasound echo signal to first mode second ultrasound echo signal.
Display module 25 is for showing aforesaid first mode first view data and the second pattern first view data; Or show aforesaid first mode second view data and the second pattern second view data.
Wherein, in the supersonic imaging device of the present embodiment, the second pattern second emitting voltage is higher than the second pattern first emitting voltage, and first mode second emitting voltage is lower than first mode first emitting voltage.
In embodiments of the invention, voltage control module 20 is also after high sensitivity image-forming step continues the first Preset Time, and the emitting voltage controlling transmitter module 21 reverts to first mode first emitting voltage (during first mode imaging) or the second pattern first emitting voltage (during the second mode imaging).
In embodiments of the invention, in the default out-of-service time after the emitting voltage of transmitter module 21 reverts to first mode first emitting voltage or the second pattern first emitting voltage, forbid triggering aforesaid high sensitivity image-forming step.
Similarly, in embodiments of the invention, aforesaid first Preset Time and default out-of-service time meet: make when supersonic imaging device switches back and forth at high sensitivity image-forming step and normal imaging step, the surface temperature rise of ultrasonic probe meets the limitation standard of detecting head surface temperature rise in medical supersonic.
To sum up, the present invention proposes a kind of ultrasonic imaging method and the device that realize high sensitivity blood flow imaging, the sensitivity of blood flow imaging is significantly improved by directly improving the method for the second impulse ejection voltage under the second Mode scans, to small blood flow and difficult patient, there is obvious advantage, improve the diagnosis confidence of doctor.
It will be appreciated by those skilled in the art that, in above-mentioned embodiment, all or part of step of various method can be carried out instruction related hardware by program and completes, this program can be stored in a computer-readable recording medium, and storage medium can comprise: read only memory, random access memory, disk or CD etc.
Above content is in conjunction with concrete embodiment further description made for the present invention, can not assert that specific embodiment of the invention is confined to these explanations.For general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, some simple deduction or replace can also be made.

Claims (13)

1. realize a ultrasonic imaging method for high sensitivity imaging, it is characterized in that, comprising:
Normal imaging step, described normal imaging step comprises:
First emitting voltage launches first mode pulse signal to object to be detected in a first pattern, receive first mode first ultrasound echo signal returned from described object to be detected, process to obtain first mode first view data to described first mode first ultrasound echo signal;
First emitting voltage launches the second patterned pulse signal to described object to be detected in a second mode, receive the second pattern first ultrasound echo signal returned from described object to be detected, process to obtain the second pattern first view data to described second pattern first ultrasound echo signal;
Show described first mode first view data and described second pattern first view data;
After receiving the triggering signal entering high sensitivity image-forming step, perform high sensitivity image-forming step, described high sensitivity image-forming step comprises:
Second emitting voltage launches first mode pulse signal to described object to be detected in a first pattern, receive first mode second ultrasound echo signal returned from described object to be detected, process to obtain first mode second view data to described first mode second ultrasound echo signal;
Second emitting voltage launches the second patterned pulse signal to described object to be detected in a second mode, receive the second pattern second ultrasound echo signal returned from described object to be detected, process to obtain the second pattern second view data to described second pattern second ultrasound echo signal;
Show described first mode second view data and described second pattern second view data;
Wherein said second pattern second emitting voltage is higher than described second pattern first emitting voltage, and described first mode second emitting voltage is lower than described first mode first emitting voltage.
2. ultrasonic imaging method as claimed in claim 1, is characterized in that, also comprise:
Recover normal imaging step, after described high sensitivity image-forming step continues the first Preset Time, recover to perform described normal imaging step.
3. ultrasonic imaging method as claimed in claim 2, is characterized in that, also comprise:
Described high sensitivity image-forming step reverted in the default out-of-service time after described normal imaging step, forbade triggering described high sensitivity image-forming step.
4. ultrasonic imaging method as claimed in claim 1, is characterized in that, described second pattern second emitting voltage meets the criterion that in medical supersonic, sound exports.
5. ultrasonic imaging method as claimed in claim 3, it is characterized in that, described first Preset Time and described default out-of-service time meet: make when supersonic imaging device switches back and forth between described high sensitivity image-forming step and described normal imaging step, the surface temperature rise of ultrasonic probe meets the limitation standard of detecting head surface temperature rise in medical supersonic.
6. as the ultrasonic imaging method in claim 2 to 5 as described in any one, it is characterized in that, described first Preset Time is longer, and the voltage amplitude that described second pattern second emitting voltage improves relative to described second pattern first voltage is less.
7. ultrasonic imaging method as claimed in claim 1, it is characterized in that, described first mode second emitting voltage is zero, and wherein reads described first mode first view data as described first mode second view data.
8. ultrasonic imaging method as claimed in any of claims 1 to 7 in one of claims, it is characterized in that, described first mode is B-mode, M-mode and/or D mode.
9. ultrasonic imaging method as claimed in any of claims 1 to 7 in one of claims, it is characterized in that, described second pattern is C mode and/or D mode.
10. a supersonic imaging device, is characterized in that, comprising:
Ultrasonic probe;
Transmitter module, described transmitter module is used in normal imaging step, first emitting voltage launches first mode pulse signal by described ultrasonic probe to object to be detected in a first pattern, and the first emitting voltage launches the second patterned pulse signal by described ultrasonic probe to object to be detected in a second mode; And in high sensitivity image-forming step, second emitting voltage launches first mode pulse signal by described ultrasonic probe to described object to be detected in a first pattern, and the second emitting voltage launches the second patterned pulse signal by described ultrasonic probe to object to be detected in a second mode;
Voltage control module, described voltage control module is used in normal imaging step, and the emitting voltage controlling described transmitter module is described first mode first emitting voltage or described second pattern first emitting voltage; And for after receiving the triggering signal entering high sensitivity image-forming step, the emitting voltage controlling described transmitter module changes described first mode second emitting voltage or described second pattern second emitting voltage into;
Receiver module, described receiver module is used in normal imaging step, receives first mode first ultrasound echo signal returned from described object to be detected and the second pattern first ultrasound echo signal returned from described object to be detected; And in high sensitivity image-forming step, receive first mode second ultrasound echo signal returned from described object to be detected and the second pattern second ultrasound echo signal returned from described object to be detected;
Signal processing module, described signal processing module is used in normal imaging step, processes to obtain first mode first view data and process to obtain the second pattern first view data to described second pattern first ultrasound echo signal to described first mode first ultrasound echo signal; And in high sensitivity image-forming step, process to obtain first mode second view data and process to obtain the second pattern second view data to described second pattern second ultrasound echo signal to described first mode second ultrasound echo signal;
Display module, for showing described first mode first view data and described second pattern first view data or showing described first mode second view data and described second pattern second view data;
Wherein said second pattern second emitting voltage is higher than described second pattern first emitting voltage, and described first mode second emitting voltage is lower than described first mode first emitting voltage.
11. supersonic imaging devices as claimed in claim 10, it is characterized in that, described voltage control module is after described high sensitivity image-forming step continues the first Preset Time, and the emitting voltage controlling described transmitter module reverts to described first mode first emitting voltage or described second pattern first emitting voltage.
12. supersonic imaging devices as claimed in claim 11, it is characterized in that, in the default out-of-service time after the emitting voltage of described transmitter module reverts to described first mode first emitting voltage or described second pattern first emitting voltage, forbid triggering described high sensitivity image-forming step.
13. supersonic imaging devices as claimed in claim 12, it is characterized in that, described first Preset Time and described default out-of-service time meet: make when supersonic imaging device switches back and forth between described high sensitivity image-forming step and described normal imaging step, the surface temperature rise of ultrasonic probe meets the limitation standard of detecting head surface temperature rise in medical supersonic.
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