CN104403229A - Medical antibacterial PVC(polyvinyl chloride) film and preparation method thereof - Google Patents
Medical antibacterial PVC(polyvinyl chloride) film and preparation method thereof Download PDFInfo
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- CN104403229A CN104403229A CN201410676976.0A CN201410676976A CN104403229A CN 104403229 A CN104403229 A CN 104403229A CN 201410676976 A CN201410676976 A CN 201410676976A CN 104403229 A CN104403229 A CN 104403229A
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L27/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers
- C08L27/02—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L27/04—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment containing chlorine atoms
- C08L27/06—Homopolymers or copolymers of vinyl chloride
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K2201/00—Specific properties of additives
- C08K2201/014—Additives containing two or more different additives of the same subgroup in C08K
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/16—Applications used for films
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Abstract
The invention discloses a medical antibacterial PVC(polyvinyl chloride) film and a preparation method thereof. The method comprises the following steps: weighing materials of PVC, DOP(dioctyl-phthalate), a nanometer zirconium phosphate carrying silver antibacterial agent, a DBP(double base propellant), a stabilizing agent, calcium carbonate, dicumyl peroxide, barium stearate, antioxidant, cadmium stearate, epoxy soybean oil, sodium hydrogen sulfite and dibutyl tin dialurate, uniformly mixing the materials, and then extruding the mixed materials to make grains so as to obtain the film. The elongation rate of products is 45-85%, and the tensile strength is 45-65 MPa; the antibacterial rate to enterobacteria is 95.9-99.9%, and the antibacterial rate to golden staphylococcocci is 97.5-99.5%; at the temperature of 100 DEG C, the lateral shrinkage is 25-45%; the right angle tear strength is 60-80 N/m.
Description
Technical field
The application belongs to medical new material technology field, particularly relates to a kind of medical antibacterial PVC film and preparation method thereof.
Background technology
Biomedical material refers to a class and has property, features, for artificial organs, surgical repair, physiotherapy and rehabilitation, diagnosis, treatment illness, and can not produce dysgenic material to tissue.Present various synthetic materials and natural macromolecular material, metal and alloy material, pottery and carbon materials and various matrix material, it is made product and has been widely used in clinical and scientific research.The research of Chinese medical macromolecular material starts to walk comparatively early, development is very fast.About You50Duo Ge unit is engaged in the research of this respect at present, existing medical macromolecular materials kind more than 60, and goods reach more than 400 and plant, and the polymethylmethacrylate for medical treatment reaches 300 t every year.But the research of Chinese medical macromolecular material is still in experience and semiempirical stage [5] at present, does not also have can be based upon on the basis of molecular designing.Therefore, should with the structure and theory of material, the chemical constitution of material, the pass between surface properties and the consistency of life entity tissue are according to researching and developing novel material.Medical macromolecular materials will be applied to organism must will meet the strict requirement such as biological functionality, biocompatibility, chemical stability and workability simultaneously.The research and development direction of bio-medical material mainly comprises following several respects: 1, tissue engineering material, organizational project is that application life science and the principle of engineering and method build a biological device, safeguard, promote the growth of human body cell and tissue, to recover the function of damaged tissue or organ.Its main task be realize damaged tissue and organ reparation or build again, prolongs life and improving health conditions.Its method is: particular organization's cell " plantation " is good in a kind of biocompatibility, by the biomaterial of human body progressively degraded and absorbed, can form cell-biomaterial composites; The growth breeding that biomaterial is cell provides three-dimensional space and Nutrition and Metabolism environment; Along with the degraded of material and the breeding of cell, form the new tissue that adapts with self function and morphology or organ.The vital biological tissue of this tool or organ can carry out the reconstruction of structure, morphology and function to disease damage tissue or organ, and reach permanent alternative.2. Nano biomedical material---drug release material and gene therapy vector material polymer drug Co ntrolled release system can not only improve drug effect, simplify administering mode, greatly reduce the toxic side effect of medicine, and nano target Co ntrolled release system makes medicine at predetermined position, by the dosage of design, in the time range needed, with certain speed slow releasing in vivo, thus reach certain disease for the treatment of or regulate the object of giving birth to.The exploitation of disposable injection or oral polymer vaccine preparation, by the shortcoming overcoming plain vaccine and need multiple injection to prove effective, and the dark attention by people.The development of polymer pregnancy vaccine again the growth difference for the mankind is provided one easy, have no side effect, foolproof novel method, and likely become the important measures of bringing the growth of population under control future.Gene therapy imports normal gene in specific cell (cancer cells); defect or pathogenic gene are repaired; or import and can give expression to the protein gene with Therapeutic cancer function; or importing can stop the gene fragment of Disease-causing gene synthetic protein in body to be had an effect to organize Disease-causing gene, thus reach the object for the treatment of.The key of gene therapy is the carrier of quiding gene, and only by carrier, normal gene just can enter in nucleus.At present, high molecule nano material and liposome are the ideal carriers of gene therapy, bearer cap is large, safety performance is high feature that it has.Recently the new dendrimer material synthesized merits attention as the carrier of channel genes.3. composite biological material, as the main body of hard tissue repairing material, composite biological material is in widespread attention, and it has, and intensity is high, the feature of good toughness, has been widely used in clinical at present.By having the compound of different performance material, can reach the effect of " learning from other's strong points to offset one's weaknesses ", effectively can solve the intensity of material, toughness and biocompatibility issues, be the effective means of biomaterial new varieties.The consistency improved between composite material interface is the major subjects of matrix material research.Different according to use-pattern, studying more is the compound research of alloy, carbon fiber/macromolecular material, inorganic materials (biological ceramics, bioactivity glass), macromolecular material.4. biomaterial surface modification is permanent problem, except the novel material of design, processability excellence, also improves material property by carrying out chemical conversion treatment, surface physics modification and bio-modification to traditional material.Material surface modifying is the permanent problem of biomaterial research.As: when selecting synthesized polymer material to manufacture artificial organ, can by the method for copolymerization, two or more Polymer Synthesizings together, make that the hydrophilic radical in material molecule is thinly scattered to be distributed in everywhere, in microcosmic body uniform texture state, greatly anti-thrombus function can be improved like this.Look forward to the future, the injection of new and high technology will greatly strengthen the vigor of medical macromolecular materials industry.The wear debris problem that the joint prosthesis faced in the application of general medical material lost efficacy, the anticoagulation problem of cardiovascular device, the degradation mechanism problem of material, the problem such as reliable method and model of evaluating material and implant long-term safety, reliability is expected to improve.But compare with developed country, the scale of medical polymer related industries and the level of research and development of China all also have larger gap.After China's entry into the WTO, medical material industry will face significant challenge and opportunity, so should under the support energetically of country, trans-departmental, interdiscipline is worked in concert, by walking to rely on one's own efforts the road that combines with technology introduction, emphasis input in biomaterial, molecular designing, human simulation, intelligent medicine control are executed etc.Medical macromolecular materials will make larger contribution for promoting the well-being of mankind.
Medical macromolecular materials are the polymer materialss manufacturing human body viscera, vitro in organ, pharmaceutical dosage form and medicine equipment.Over 20 years, the macromolecular material for this respect has polyvinyl chloride, natural rubber, polyethylene, polymeric amide, polypropylene, polystyrene, silicon rubber, polyester, tetrafluoroethylene, polymethylmethacrylate and urethane etc.Medical macromolecular materials are used for human body, are directly connected to the life and health of people, to the requirement of its performance are generally: security: must be nontoxic or side effect is few.This just requires that polymer purity is high, and production environment is very clean, and remaining of reagent and additive in polymerization is few, and foreign matter content is ppm level, guarantees anosis, nontoxic propagation conditions.Physics, chemistry and mechanical property: the requirement that need meet medical required Design and Features.As aging in hardness, elasticity, physical strength, fatigue strength, creep, abrasion, water-absorbent, stripping property, resistance to enzymatic and body etc.For heart valve, preferably can use 250,000 hours, require that fatigue resistance is good especially.In addition, also require to be convenient to sterilization, damp and hot sterilization (120 ~ 140 ° of C), dry heat sterilization (160 ~ 190 ° of C), radiation sterilization or chemical treatment sterilization can be tolerated, and do not reduce the performance of material.Require good processability, required different shape can be processed into, and not damage its proper property.Adaptability: comprise the adaptability with other materials in medical treatment product, the adaptability of material and the various tissue of human body.After material implant into body, require over a long time on body fluid without impact; Good with blood compatibility, harmless to blood ingredient, not blood coagulation, not haemolysis, do not form thrombus; Foreign reacts, and not damaged tissue in human body, not carcinogenic teratogenesis, can not cause inflammation necrosis, hamartoplasia etc.Specific function: different Application Areass, requires that material has certain specific function respectively.Such as: there is the kidney machine filtering membrane, the artificial lung gas-exchange membrane that are separated dialysis function, and the material etc. of the degassed body of artificial blood suction, all require separation special separately through function.In most of the cases, the surface chemistry composition of existing macromolecular material is difficult to meet above-mentioned requirements with structure, usually will adopt surface modification treatment, as graft copolymerization, to improve the performances such as its anticoagulant property.
Antibiotic plastic be a class in environment for use itself to stain bacterium on plastics, mould, the female bacterium of alcohol, algae even virus etc. rise and suppress or the plastics of killing action, keep itself clean by suppressing the breeding of microorganism.At present, antibiotic plastic obtains mainly through the method for adding a small amount of antiseptic-germicide in common plastics.First antibiotic plastic will meet the exclusive requirement to performances such as its physics, chemistry, machineries when plastics use as basic material in using, will consider to possess the requirement of this specific function antibacterial and consequent additional factor simultaneously.The research of Chinese medical macromolecular material starts to walk comparatively early, development is very fast.About You50Duo Ge unit is engaged in the research of this respect at present, existing medical macromolecular materials kind more than 60, and goods reach more than 400 and plant, and the poly-methyl PVC acid methyl esters for medical treatment reaches 300t every year.But the research of Chinese medical macromolecular material is still in experience and semiempirical stage at present, does not also have can be based upon on the basis of molecular designing.Therefore, should with the structure and theory of material, the chemical constitution of material, the pass between surface properties and the consistency of life entity tissue are according to researching and developing novel material.Medical macromolecular materials will be applied to organism must will meet the strict requirement such as biological functionality, biocompatibility, chemical stability and workability simultaneously.Development trend, research and development meet biocompatibility and blood compatibility material, attach most importance to polyolefine, polysiloxane, fluorocarbon polymer and urethane; Exploitation Drug controlled release, artificial organ, medicine equipment and control fertility material therefor.Development of small-scale, Portable belt, in the artificial organs device of the type such as burying.
Polyvinyl chloride, English abbreviation PVC(Polyvinyl chloride polymer=PVC molecular structure), be the thermoplastic resin be polymerized under initiator effect by vinylchlorid.It is the homopolymer of vinylchlorid.Ryuron and vinyl chloride copolymer system are referred to as vinyl chloride resin.PVC is the white powder of amorphous structure, and the degree of branching is less.Industrial PVC molecular weight generally, in 50,000 ~ 120,000 scopes, has larger polymolecularity, the reduction of molecular weight with polymerisation temperature and increasing; Without definite melting point, 80 ~ 85 DEG C start to soften, and 130 DEG C become viscoelastic state, and 160 ~ 180 DEG C start to change viscous state into; There is good mechanical property, about tensile strength 60MPa, shock strength 5 ~ 10kJ/m2; There are excellent dielectric properties.But to the poor stability of light and heat, more than 100 DEG C or through long-time exposure in sunshine, will decompose and produce hydrogenchloride, and autocatalytically is decomposed further, cause variable color, physical and mechanical properties also declines rapidly, must add stablizer in actual applications to improve the stability to light and heat.PVC is very hard, and solvability is also very poor, and can only be dissolved in the minority solvents such as pimelinketone, ethylene dichloride and tetrahydrofuran (THF), all stable to organic and mineral acid, alkali, salt, chemical stability reduces with the rising of use temperature.PVC is dissolved in acetone-dithiocarbonic anhydride or Acetone-Benzene mixed solvent, forms fiber for dry-spinning or wet-spinning, claims polyvinyl chloride fibre, have difficult combustion, acid and alkali-resistance, antimicrobial, wear-resisting, environmental protection characteristic and there is good heat retention and elasticity.And popularizing along with humanity concept, and the formation of novel harmonious society, design high medical antibacterial PVC film of a kind of intestinal bacteria antibiotic rate, streptococcus aureus antibiotic rate, tensile strength and elongation and preparation method thereof and be very important.
Summary of the invention
the technical problem solved:
The application, for above-mentioned technical problem, provides a kind of medical antibacterial PVC film and preparation method thereof, solves the technical problems such as existing medical novel material intestinal bacteria antibiotic rate, streptococcus aureus antibiotic rate, tensile strength and elongation are low.
technical scheme:
A kind of medical antibacterial PVC film, the raw materials by weight portion proportioning of described medical antibacterial PVC film is as follows: PVC100 part; DOP30-50 part; Nanometer silver-zirconium phosphate antimicrobial 0.5-4.5 part; DBP10-30 part; Diisononyl hexanodioic acid 30-50 part; DOS5-15 part; Stablizer 1.5-5.5 part; Calcium carbonate 0.5-2.5 part; Dihexyl hexanodioic acid 5-25 part; Barium stearate is 1.5-3.5 part; Oxidation inhibitor 0.05-0.45 part; Cadmium stearate is 1-3 part; Epoxy soybean oil 10-30 part; Sodium bisulfite is 0.1-0.5 part; Dibutyl tin laurate is 0.5-2.5 part.
As a preferred technical solution of the present invention: the raw materials by weight portion proportioning of described medical antibacterial PVC film is as follows: PVC100 part; DOP35-45 part; Nanometer silver-zirconium phosphate antimicrobial 1.5-3.5 part; DBP15-25 part; Diisononyl hexanodioic acid 35-45 part; DOS8-12 part; Stablizer 2.5-4.5 part; Calcium carbonate 1-2 part; Dihexyl hexanodioic acid 10-20 part; Barium stearate is 2-3 part; Oxidation inhibitor 0.15-0.35 part; Cadmium stearate is 1.5-2.5 part; Epoxy soybean oil 15-25 part; Sodium bisulfite is 0.2-0.4 part; Dibutyl tin laurate is 1-2 part.
As a preferred technical solution of the present invention: the raw materials by weight portion proportioning of described medical antibacterial PVC film is as follows: PVC100 part; DOP40 part; Nanometer silver-zirconium phosphate antimicrobial 2.5 parts; DBP20 part; Diisononyl hexanodioic acid 40 parts; DOS10 part; Stablizer 3.5 parts; 1.5 parts, calcium carbonate; Dihexyl hexanodioic acid 15 parts; Barium stearate is 2.5 parts; 0.25 part, oxidation inhibitor; Cadmium stearate is 2 parts; Epoxy soybean oil 20 parts; Sodium bisulfite is 0.3 part; Dibutyl tin laurate is 1.5 parts.
As a preferred technical solution of the present invention: described stablizer adopts organotin stabilizer or liquid barium cadmium stabilizer.
As a preferred technical solution of the present invention: described oxidation inhibitor adopts antioxidant 1010 or antioxidant CA.
As a preferred technical solution of the present invention: the preparation method of described medical antibacterial PVC film, comprises the steps:
The first step: take PVC, DOP, nanometer silver-zirconium phosphate antimicrobial, DBP, diisononyl hexanodioic acid, DOS, stablizer, calcium carbonate, dicumyl peroxide, barium stearate, oxidation inhibitor, cadmium stearate, epoxy soybean oil, sodium bisulfite and dibutyl tin laurate according to parts by weight proportioning;
Second step: PVC, DOP, nanometer silver-zirconium phosphate antimicrobial, DBP and barium stearate are dropped in reactor and is heated to 75-95 DEG C, stir 20-40min, stirring velocity 200-300 rev/min;
3rd step: then add surplus stock, be warming up to 105-125 DEG C, stirs 10-30min, stirring velocity 200-400 rev/min;
4th step: mixed material is dropped into extruding pelletization in twin screw extruder, barrel temperature 80 DEG C, 100 DEG C, 135 DEG C, 160 DEG C, 170 DEG C, 185 DEG C, 190 DEG C and 200 DEG C, screw speed 55-75 rev/min, pulling speed 45-55m/min, blow-up ratio 3.5.
beneficial effect:
A kind of medical antibacterial PVC film of the present invention and preparation method thereof adopts above technical scheme compared with prior art, has following technique effect: 1, product elongation 45-85%, tensile strength 45-65MPa; 2, intestinal bacteria antibiotic rate 95.9-99.9%, streptococcus aureus antibiotic rate 97.5-99.5%; 3,100 DEG C time, lateral shrinkage is 25-45%; 4, angle tear strength 60-80N/m, the widespread production not division of history into periods can replace current material.
Embodiment
embodiment 1:
PVC100 part is taken according to parts by weight proportioning; DOP30 part; Nanometer silver-zirconium phosphate antimicrobial 0.5 part; DBP10 part; Diisononyl hexanodioic acid 30 parts; DOS5 part; Liquid barium cadmium stabilizer 1.5 parts; 0.5 part, calcium carbonate; Dihexyl hexanodioic acid 5 parts; Barium stearate is 1.5 parts; Antioxidant 1010 is 0.05 part; Cadmium stearate is 1 part; Epoxy soybean oil 10 parts; Sodium bisulfite is 0.1 part; Dibutyl tin laurate is 0.5 part.
PVC, DOP, nanometer silver-zirconium phosphate antimicrobial, DBP and barium stearate are dropped in reactor and be heated to 75 DEG C, stir 20min, stirring velocity 200 revs/min, then adds surplus stock, is warming up to 105 DEG C, stirs 10min, stirring velocity 200 revs/min.
Mixed material is dropped into extruding pelletization in twin screw extruder, barrel temperature 80 DEG C, 100 DEG C, 135 DEG C, 160 DEG C, 170 DEG C, 185 DEG C, 190 DEG C and 200 DEG C, screw speed 55 revs/min, pulling speed 45m/min, blow-up ratio 3.5.
Product elongation 45%, tensile strength 45MPa; Intestinal bacteria antibiotic rate 95.9%, streptococcus aureus antibiotic rate 97.5%; 100 DEG C time, lateral shrinkage is 25%; Angle tear strength 60N/m.
embodiment 2:
PVC100 part is taken according to parts by weight proportioning; DOP50 part; Nanometer silver-zirconium phosphate antimicrobial 4.5 parts; DBP30 part; Diisononyl hexanodioic acid 50 parts; DOS15 part; Liquid barium cadmium stabilizer 5.5 parts; 2.5 parts, calcium carbonate; Dihexyl hexanodioic acid 25 parts; Barium stearate is 3.5 parts; Antioxidant 1010 is 0.45 part; Cadmium stearate is 3 parts; Epoxy soybean oil 30 parts; Sodium bisulfite is 0.5 part; Dibutyl tin laurate is 2.5 parts.
PVC, DOP, nanometer silver-zirconium phosphate antimicrobial, DBP and barium stearate are dropped in reactor and be heated to 95 DEG C, stir 40min, stirring velocity 300 revs/min, then adds surplus stock, is warming up to 125 DEG C, stirs 30min, stirring velocity 400 revs/min.
Mixed material is dropped into extruding pelletization in twin screw extruder, barrel temperature 80 DEG C, 100 DEG C, 135 DEG C, 160 DEG C, 170 DEG C, 185 DEG C, 190 DEG C and 200 DEG C, screw speed 75 revs/min, pulling speed 55m/min, blow-up ratio 3.5.
Product elongation 55%, tensile strength 50MPa; Intestinal bacteria antibiotic rate 96.9%, streptococcus aureus antibiotic rate 98%; 100 DEG C time, lateral shrinkage is 30%; Angle tear strength 65N/m.
embodiment 3:
PVC100 part is taken according to parts by weight proportioning; DOP35 part; Nanometer silver-zirconium phosphate antimicrobial 1.5 parts; DBP15 part; Diisononyl hexanodioic acid 35 parts; DOS8 part; Liquid barium cadmium stabilizer 2.5 parts; 1 part, calcium carbonate; Dihexyl hexanodioic acid 10 parts; Barium stearate is 2 parts; Antioxidant CA 0.15 part; Cadmium stearate is 1.5 parts; Epoxy soybean oil 15 parts; Sodium bisulfite is 0.2 part; Dibutyl tin laurate is 1 part.
PVC, DOP, nanometer silver-zirconium phosphate antimicrobial, DBP and barium stearate are dropped in reactor and be heated to 80 DEG C, stir 25min, stirring velocity 220 revs/min, then adds surplus stock, is warming up to 110 DEG C, stirs 15min, stirring velocity 250 revs/min.
Mixed material is dropped into extruding pelletization in twin screw extruder, barrel temperature 80 DEG C, 100 DEG C, 135 DEG C, 160 DEG C, 170 DEG C, 185 DEG C, 190 DEG C and 200 DEG C, screw speed 60 revs/min, pulling speed 48m/min, blow-up ratio 3.5.
Product elongation 65%, tensile strength 55MPa; Intestinal bacteria antibiotic rate 97.9%, streptococcus aureus antibiotic rate 98.5%; 100 DEG C time, lateral shrinkage is 35%; Angle tear strength 70N/m.
embodiment 4:
PVC100 part is taken according to parts by weight proportioning; DOP45 part; Nanometer silver-zirconium phosphate antimicrobial 3.5 parts; DBP25 part; Diisononyl hexanodioic acid 45 parts; DOS12 part; Organotin stabilizer 4.5 parts; 2 parts, calcium carbonate; Dihexyl hexanodioic acid 20 parts; Barium stearate is 3 parts; Antioxidant CA 0.35 part; Cadmium stearate is 2.5 parts; Epoxy soybean oil 25 parts; Sodium bisulfite is 0.4 part; Dibutyl tin laurate is 2 parts.
PVC, DOP, nanometer silver-zirconium phosphate antimicrobial, DBP and barium stearate are dropped in reactor and be heated to 90 DEG C, stir 35min, stirring velocity 280 revs/min, then adds surplus stock, is warming up to 120 DEG C, stirs 25min, stirring velocity 350 revs/min.
Mixed material is dropped into extruding pelletization in twin screw extruder, barrel temperature 80 DEG C, 100 DEG C, 135 DEG C, 160 DEG C, 170 DEG C, 185 DEG C, 190 DEG C and 200 DEG C, screw speed 70 revs/min, pulling speed 53m/min, blow-up ratio 3.5.
Product elongation 75%, tensile strength 60MPa; Intestinal bacteria antibiotic rate 98.9%, streptococcus aureus antibiotic rate 99%; 100 DEG C time, lateral shrinkage is 40%; Angle tear strength 75N/m.
embodiment 5:
PVC100 part is taken according to parts by weight proportioning; DOP40 part; Nanometer silver-zirconium phosphate antimicrobial 2.5 parts; DBP20 part; Diisononyl hexanodioic acid 40 parts; DOS10 part; Organotin stabilizer 3.5 parts; 1.5 parts, calcium carbonate; Dihexyl hexanodioic acid 15 parts; Barium stearate is 2.5 parts; Antioxidant CA 0.25 part; Cadmium stearate is 2 parts; Epoxy soybean oil 20 parts; Sodium bisulfite is 0.3 part; Dibutyl tin laurate is 1.5 parts.
PVC, DOP, nanometer silver-zirconium phosphate antimicrobial, DBP and barium stearate are dropped in reactor and be heated to 85 DEG C, stir 30min, stirring velocity 250 revs/min, then adds surplus stock, is warming up to 115 DEG C, stirs 20min, stirring velocity 300 revs/min.
Mixed material is dropped into extruding pelletization in twin screw extruder, barrel temperature 80 DEG C, 100 DEG C, 135 DEG C, 160 DEG C, 170 DEG C, 185 DEG C, 190 DEG C and 200 DEG C, screw speed 65 revs/min, pulling speed 50m/min, blow-up ratio 3.5.
Product elongation 85%, tensile strength 65MPa; Intestinal bacteria antibiotic rate 99.9%, streptococcus aureus antibiotic rate 99.5%; 100 DEG C time, lateral shrinkage is 45%; Angle tear strength 80N/m.
Composition all components in above embodiment all can business be bought.
Above-described embodiment is just for setting forth content of the present invention, instead of restriction, and any change therefore in the implication suitable with claims of the present invention and scope, all should think to be included in the scope of claims.
Claims (6)
1. a medical antibacterial PVC film, is characterized in that the raw materials by weight portion proportioning of described medical antibacterial PVC film is as follows: PVC100 part; DOP30-50 part; Nanometer silver-zirconium phosphate antimicrobial 0.5-4.5 part; DBP10-30 part; Diisononyl hexanodioic acid 30-50 part; DOS5-15 part; Stablizer 1.5-5.5 part; Calcium carbonate 0.5-2.5 part; Dihexyl hexanodioic acid 5-25 part; Barium stearate is 1.5-3.5 part; Oxidation inhibitor 0.05-0.45 part; Cadmium stearate is 1-3 part; Epoxy soybean oil 10-30 part; Sodium bisulfite is 0.1-0.5 part; Dibutyl tin laurate is 0.5-2.5 part.
2. a kind of medical antibacterial PVC film according to claim 1, is characterized in that described medical antibacterial PVC film raw materials by weight portion proportioning is as follows: PVC100 part; DOP35-45 part; Nanometer silver-zirconium phosphate antimicrobial 1.5-3.5 part; DBP15-25 part; Diisononyl hexanodioic acid 35-45 part; DOS8-12 part; Stablizer 2.5-4.5 part; Calcium carbonate 1-2 part; Dihexyl hexanodioic acid 10-20 part; Barium stearate is 2-3 part; Oxidation inhibitor 0.15-0.35 part; Cadmium stearate is 1.5-2.5 part; Epoxy soybean oil 15-25 part; Sodium bisulfite is 0.2-0.4 part; Dibutyl tin laurate is 1-2 part.
3. a kind of medical antibacterial PVC film according to claim 1, is characterized in that the raw materials by weight portion proportioning of described medical antibacterial PVC film is as follows: PVC100 part; DOP40 part; Nanometer silver-zirconium phosphate antimicrobial 2.5 parts; DBP20 part; Diisononyl hexanodioic acid 40 parts; DOS10 part; Stablizer 3.5 parts; 1.5 parts, calcium carbonate; Dihexyl hexanodioic acid 15 parts; Barium stearate is 2.5 parts; 0.25 part, oxidation inhibitor; Cadmium stearate is 2 parts; Epoxy soybean oil 20 parts; Sodium bisulfite is 0.3 part; Dibutyl tin laurate is 1.5 parts.
4. a kind of medical antibacterial PVC film according to claim 1, is characterized in that: described stablizer adopts organotin stabilizer or liquid barium cadmium stabilizer.
5. a kind of medical antibacterial PVC film according to claim 1, is characterized in that: described oxidation inhibitor adopts antioxidant 1010 or antioxidant CA.
6. a preparation method for medical antibacterial PVC film described in claim 1, is characterized in that, comprise the steps:
The first step: take PVC, DOP, nanometer silver-zirconium phosphate antimicrobial, DBP, diisononyl hexanodioic acid, DOS, stablizer, calcium carbonate, dicumyl peroxide, barium stearate, oxidation inhibitor, cadmium stearate, epoxy soybean oil, sodium bisulfite and dibutyl tin laurate according to parts by weight proportioning;
Second step: PVC, DOP, nanometer silver-zirconium phosphate antimicrobial, DBP and barium stearate are dropped in reactor and is heated to 75-95 DEG C, stir 20-40min, stirring velocity 200-300 rev/min;
3rd step: then add surplus stock, be warming up to 105-125 DEG C, stirs 10-30min, stirring velocity 200-400 rev/min;
4th step: mixed material is dropped into extruding pelletization in twin screw extruder, barrel temperature 80 DEG C, 100 DEG C, 135 DEG C, 160 DEG C, 170 DEG C, 185 DEG C, 190 DEG C and 200 DEG C, screw speed 55-75 rev/min, pulling speed 45-55m/min, blow-up ratio 3.5.
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105504581A (en) * | 2015-12-25 | 2016-04-20 | 黄山豪泰塑胶有限公司 | Antibacterial PVC (polyvinyl chloride) film with self-cleaning function |
| CN105713317A (en) * | 2016-03-23 | 2016-06-29 | 苏州市贝克生物科技有限公司 | Medical antibacterial PVC film and preparation method thereof |
| CN106147084A (en) * | 2016-08-24 | 2016-11-23 | 安徽顺彤包装材料有限公司 | A kind of antibacterial medical packaging material and preparation method thereof |
| CN106280131A (en) * | 2016-08-31 | 2017-01-04 | 黄山豪泰塑胶有限公司 | A kind of PVC decorative Film of heat-proof combustion-resistant and its preparation method and application |
| CN106317703A (en) * | 2016-08-31 | 2017-01-11 | 黄山豪泰塑胶有限公司 | PVC (polyvinyl chloride) film as well as preparation method and application thereof |
| CN106589693A (en) * | 2016-12-13 | 2017-04-26 | 无锡市四方达高分子材料有限公司 | Medical antibacterial polymer material |
| CN106674798A (en) * | 2016-11-22 | 2017-05-17 | 孙祎 | Method for preparing antibacterial plastic by nanometer silver-loaded carbon fiber |
| CN108559123A (en) * | 2018-05-15 | 2018-09-21 | 东莞市联洲知识产权运营管理有限公司 | A kind of bio-medical PVC material and preparation method thereof |
| CN109354793A (en) * | 2018-09-04 | 2019-02-19 | 浙江天原医用材料有限公司 | A kind of high-strength PVC medical material and preparation method thereof |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105504581A (en) * | 2015-12-25 | 2016-04-20 | 黄山豪泰塑胶有限公司 | Antibacterial PVC (polyvinyl chloride) film with self-cleaning function |
| CN105713317A (en) * | 2016-03-23 | 2016-06-29 | 苏州市贝克生物科技有限公司 | Medical antibacterial PVC film and preparation method thereof |
| CN106147084A (en) * | 2016-08-24 | 2016-11-23 | 安徽顺彤包装材料有限公司 | A kind of antibacterial medical packaging material and preparation method thereof |
| CN106280131A (en) * | 2016-08-31 | 2017-01-04 | 黄山豪泰塑胶有限公司 | A kind of PVC decorative Film of heat-proof combustion-resistant and its preparation method and application |
| CN106317703A (en) * | 2016-08-31 | 2017-01-11 | 黄山豪泰塑胶有限公司 | PVC (polyvinyl chloride) film as well as preparation method and application thereof |
| CN106674798A (en) * | 2016-11-22 | 2017-05-17 | 孙祎 | Method for preparing antibacterial plastic by nanometer silver-loaded carbon fiber |
| CN106589693A (en) * | 2016-12-13 | 2017-04-26 | 无锡市四方达高分子材料有限公司 | Medical antibacterial polymer material |
| CN108559123A (en) * | 2018-05-15 | 2018-09-21 | 东莞市联洲知识产权运营管理有限公司 | A kind of bio-medical PVC material and preparation method thereof |
| CN109354793A (en) * | 2018-09-04 | 2019-02-19 | 浙江天原医用材料有限公司 | A kind of high-strength PVC medical material and preparation method thereof |
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