CN104399540A - 一种基于离心作用的微流控芯片液体试剂释放方法 - Google Patents
一种基于离心作用的微流控芯片液体试剂释放方法 Download PDFInfo
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- CN104399540A CN104399540A CN201410750822.1A CN201410750822A CN104399540A CN 104399540 A CN104399540 A CN 104399540A CN 201410750822 A CN201410750822 A CN 201410750822A CN 104399540 A CN104399540 A CN 104399540A
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- 239000007788 liquid Substances 0.000 title claims abstract description 39
- 239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 23
- 238000000034 method Methods 0.000 title claims abstract description 20
- 230000000694 effects Effects 0.000 title abstract 2
- 238000007789 sealing Methods 0.000 claims abstract description 54
- 238000011068 loading method Methods 0.000 claims abstract description 19
- 239000000463 material Substances 0.000 claims abstract description 14
- 239000010409 thin film Substances 0.000 claims abstract description 5
- 239000004033 plastic Substances 0.000 claims description 13
- 229920003023 plastic Polymers 0.000 claims description 13
- 229910052782 aluminium Inorganic materials 0.000 claims description 10
- 239000004411 aluminium Substances 0.000 claims description 8
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 8
- 239000002131 composite material Substances 0.000 claims description 8
- 239000005030 aluminium foil Substances 0.000 claims description 7
- 239000010408 film Substances 0.000 claims description 6
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- 238000004458 analytical method Methods 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 5
- 230000007423 decrease Effects 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
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- 238000006243 chemical reaction Methods 0.000 description 1
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- 102000004169 proteins and genes Human genes 0.000 description 1
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/52—Containers specially adapted for storing or dispensing a reagent
- B01L3/527—Containers specially adapted for storing or dispensing a reagent for a plurality of reagents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
- B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0803—Disc shape
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
- B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Centrifugal Separators (AREA)
Abstract
Description
Claims (7)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410750822.1A CN104399540B (zh) | 2014-12-10 | 2014-12-10 | 一种基于离心作用的微流控芯片液体试剂释放方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201410750822.1A CN104399540B (zh) | 2014-12-10 | 2014-12-10 | 一种基于离心作用的微流控芯片液体试剂释放方法 |
Publications (2)
Publication Number | Publication Date |
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CN104399540A true CN104399540A (zh) | 2015-03-11 |
CN104399540B CN104399540B (zh) | 2016-04-27 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201410750822.1A Active CN104399540B (zh) | 2014-12-10 | 2014-12-10 | 一种基于离心作用的微流控芯片液体试剂释放方法 |
Country Status (1)
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CN (1) | CN104399540B (zh) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3182136A1 (de) * | 2015-12-18 | 2017-06-21 | Robert Bosch Gmbh | Folienbeutel für ein mikrofluidisches analysesystem, mikrofluidisches analysesystem, verfahren zum herstellen und verfahren zum betreiben eines mikrofluidischen analysesystems |
CN108216888A (zh) * | 2018-04-02 | 2018-06-29 | 东莞东阳光科研发有限公司 | 一种液体试剂储存与释放装置及反应系统 |
CN109475869A (zh) * | 2016-07-18 | 2019-03-15 | 西门子医疗保健诊断公司 | 液体分析试剂分配设备及其相关的分析套件和使用方法 |
CN110302850A (zh) * | 2019-06-10 | 2019-10-08 | 东莞东阳光医疗智能器件研发有限公司 | 一种离心式液体释放装置 |
CN111203291A (zh) * | 2020-04-18 | 2020-05-29 | 博奥生物集团有限公司 | 一种液体存储控释装置以及生物检测芯片 |
CN114308166A (zh) * | 2022-02-24 | 2022-04-12 | 含光微纳科技(太仓)有限公司 | 一种液体试剂预埋及释放结构 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102105227A (zh) * | 2008-06-19 | 2011-06-22 | 贝林格尔英格海姆米克罗帕茨有限责任公司 | 定量供应流体的容器 |
CN103182332A (zh) * | 2013-01-22 | 2013-07-03 | 厦门大学 | 一种用于面粉增白剂检测的装置及其使用方法 |
CN103272657A (zh) * | 2013-05-27 | 2013-09-04 | 苏州扬清芯片科技有限公司 | 微流控芯片的液体存储方法 |
-
2014
- 2014-12-10 CN CN201410750822.1A patent/CN104399540B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102105227A (zh) * | 2008-06-19 | 2011-06-22 | 贝林格尔英格海姆米克罗帕茨有限责任公司 | 定量供应流体的容器 |
CN103182332A (zh) * | 2013-01-22 | 2013-07-03 | 厦门大学 | 一种用于面粉增白剂检测的装置及其使用方法 |
CN103272657A (zh) * | 2013-05-27 | 2013-09-04 | 苏州扬清芯片科技有限公司 | 微流控芯片的液体存储方法 |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3182136A1 (de) * | 2015-12-18 | 2017-06-21 | Robert Bosch Gmbh | Folienbeutel für ein mikrofluidisches analysesystem, mikrofluidisches analysesystem, verfahren zum herstellen und verfahren zum betreiben eines mikrofluidischen analysesystems |
US11027276B2 (en) | 2015-12-18 | 2021-06-08 | Robert Bosch Gmbh | Film bag for a microfluidic analysis system, microfluidic analysis system, method for producing and method for operating a microfluidic analysis system |
CN109475869A (zh) * | 2016-07-18 | 2019-03-15 | 西门子医疗保健诊断公司 | 液体分析试剂分配设备及其相关的分析套件和使用方法 |
US11040350B2 (en) | 2016-07-18 | 2021-06-22 | Siemens Healthcare Diagnostics Inc. | Liquid analytical reagent dispensing apparatus and analytical kits and methods of use related thereto |
CN109475869B (zh) * | 2016-07-18 | 2021-07-30 | 西门子医疗保健诊断公司 | 液体分析试剂分配设备及其相关的分析套件和使用方法 |
CN108216888A (zh) * | 2018-04-02 | 2018-06-29 | 东莞东阳光科研发有限公司 | 一种液体试剂储存与释放装置及反应系统 |
CN110302850A (zh) * | 2019-06-10 | 2019-10-08 | 东莞东阳光医疗智能器件研发有限公司 | 一种离心式液体释放装置 |
CN111203291A (zh) * | 2020-04-18 | 2020-05-29 | 博奥生物集团有限公司 | 一种液体存储控释装置以及生物检测芯片 |
US11577240B2 (en) | 2020-04-18 | 2023-02-14 | Capitalbio Corporation | Liquid storage and controlled-release device and biological detection chip |
CN114308166A (zh) * | 2022-02-24 | 2022-04-12 | 含光微纳科技(太仓)有限公司 | 一种液体试剂预埋及释放结构 |
Also Published As
Publication number | Publication date |
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CN104399540B (zh) | 2016-04-27 |
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Effective date of registration: 20190611 Address after: 300457 Tianjin Binhai New Area Economic and Technological Development Zone, 19 West Road 2, 2102 Co-patentee after: Micro nano core (Suzhou) Technology Co.,Ltd. Patentee after: TIANJIN MNCHIP TECHNOLOGIES Co.,Ltd. Address before: 300457 First Floor, No. 2 Coastal Service Outsourcing Industrial Park, 19 Xinhuan West Road, Tanggu District Development Zone, Tianjin Patentee before: TIANJIN MNCHIP TECHNOLOGIES Co.,Ltd. |
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Address after: 300457 Tianjin Binhai New Area Economic and Technological Development Zone, No. 122 Dongting Road, Zone A, Factory Buildings 1-4, Section 3 Office Area 1, 2, 4, 5, and Section 2 Office Area 5 Patentee after: Tianjin Weinanxin Technology Co.,Ltd. Country or region after: Zhong Guo Patentee after: Micro nano core (Suzhou) Technology Co.,Ltd. Address before: 300457 Tianjin Binhai New Area Economic and Technological Development Zone, 19 West Road 2, 2102 Patentee before: TIANJIN MNCHIP TECHNOLOGIES Co.,Ltd. Country or region before: Zhong Guo Patentee before: Micro nano core (Suzhou) Technology Co.,Ltd. |
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Effective date of registration: 20240321 Address after: 300457 Tianjin Binhai New Area Economic and Technological Development Zone, No. 122 Dongting Road, Zone A, Factory Buildings 1-4, Section 3 Office Area 1, 2, 4, 5, and Section 2 Office Area 5 Patentee after: Tianjin Weinanxin Technology Co.,Ltd. Country or region after: Zhong Guo Address before: 300457 Tianjin Binhai New Area Economic and Technological Development Zone, No. 122 Dongting Road, Zone A, Factory Buildings 1-4, Section 3 Office Area 1, 2, 4, 5, and Section 2 Office Area 5 Patentee before: Tianjin Weinanxin Technology Co.,Ltd. Country or region before: Zhong Guo Patentee before: Micro nano core (Suzhou) Technology Co.,Ltd. |
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