CN104399187A - Calibration method and device for effective laser power of low-power laser therapeutic instrument - Google Patents
Calibration method and device for effective laser power of low-power laser therapeutic instrument Download PDFInfo
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- CN104399187A CN104399187A CN201410737823.2A CN201410737823A CN104399187A CN 104399187 A CN104399187 A CN 104399187A CN 201410737823 A CN201410737823 A CN 201410737823A CN 104399187 A CN104399187 A CN 104399187A
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Abstract
The invention relates to a calibration method and a device for effective laser power of a low-power laser therapeutic instrument. The device is provided with a detecting head, a data acquisition unit and a computer, wherein the detecting head comprises photodiodes and a pre-amplification module; the data acquisition unit comprises a data acquisition card and a power supply; the data acquisition card is connected with the pre-amplification module through the detecting head, converts analog signals acquired by the photodiodes and outputted by the pre-amplification module to digital signals, and transmits the data to the computer to complete data processing; a power supply is connected with the pre-amplification module and takes charge of supplying power to the pre-amplification module. During use, the detector is mounted at the front end of the laser therapeutic instrument to ensure that the photodiodes are arranged in the surrounding space of the laser head and can receive reflected laser and scattered light within 180 degrees in the back of the laser head beam direction of the laser therapeutic instrument, so as to perform effective determination of the laser power. The calibration method and the device disclosed by the invention obtain the accurate effective laser power into the body surface by monitoring the laser retroreflection and scattered signals for the first time.
Description
[technical field]
The present invention relates to medical laser instrument technical field, specifically, relate to a kind of method and apparatus demarcating the effective laser power of low power laser therapeutic instrument.
[background technology]
Laser can produce biologic effect, promotes cell regeneration, improves blood circulation, anti-inflammatory analgetic, alleviate edema, conditioner body immunity function.The shorter laser (as 650nm) of wavelength has good curative effect to superficial tissue pathological changes, the laser (as 810nm) of infrared band has very large penetration capacity to skin, fat and the tissue such as muscular tissue and osseous tissue, therefore has good curative effect to deep tissue pathological changes.The population effect of different optical maser wavelength combination can realize the therapeutical effect to different depth.Therefore low power laser treatment obtains increasing application, such as, be used widely in the naturopathy of the orthopaedics such as bone pain, myalgia, soft tissue pain, neuralgia, the edge of a knife and wound pain, the traumatology department and Pain Management disease.
But medical circle is to some diseases, such as the curative effect of the low power laser treatment of carpal tunnel syndrome (being called for short CTS) has larger dispute, the people such as DB Piazzini in 2007 have done systematic commentary to documents (based on MEDLINE data base) delivered about CTS (providing clinical symptoms and electro physiology test and appraisal to make a definite diagnosis) expectant treatment all between in January, 1985 in May, 2006, and it is highly inconsistent for particularly pointing out laser therapy effect understanding.In laser radiation, the parameter of laser, particularly arrive the laser power in affected part, the area irradiating affected part, laser action time and the interval at every turn between laser irradiation etc. all closely related with the effect of laser to tissue, therefore the effect of accurate evaluation laser therapy is wanted, must accurately control to arrive affected part body surface, even arrive the laser parameter of therapy target, this point ignores in most clinical trial.Commentary paper [the M.Naesera that seven routine laser therapy CTS are studied that Boston University Medical School neuroscience system M.Naesera in 2006 delivers, Photobiomodulation of Pain in Carpal TunnelSyndrome:Review of Seven Laser Therapy Studies, Photomedicine and LaserSurgery, 24,101-110 (2006) .] analyze discovery: obtain the laser radiation dose (9J adopted in five cases of laser therapy CTS curative effect affirmative conclusion, 12-30J, 32J/cm
2, 225J/cm
2) apparently higher than laser radiation dose (1.8J or 6J/cm in two cases obtaining laser therapy CTS curative effect negative decision
2).But laser parameter diversity is also very large in the report of this five examples affirmative laser curative effect, optical maser wavelength has marked difference, there is 830nm, 632.8nm, 904nm, the Single wavelength of 670nm or combined wave length irradiate, and laser energy density also exists notable difference, says nothing of the difference of laser action time and interval.Can the curative effect of laser therapy CTS be guaranteed in laser power and laser energy density higher position? answer is negative.Bergen university of Norway J.Bjordal [J.Bjordal in 2007, Inadequate statistical analysis hidessignificant effect of low level laser therapy in carpel tunnel syndrome, Photomedicine and Laser Surgery, 25,530-531 (2007) .] report the unfavorable factor that laser energy too high in laser therapy CTS and energy density may bring.So, what does is the optimal parameter of CTS laser therapy? there is the threshold value of laser power, laser energy density and total irradiation laser energy? the laser parameter arriving therapy target was also never monitored in past clinical experimental study.
In the prior art, such as more widely used Man Disen Pain Therapy by Laser Diode instrument (upper Heyman Di Sen Photoelectric Co., Ltd.), only having the nominal value of laser therapeutic head output, all not comprising the laser-bounce of laser irradiating part position and the measuring device of scattering to being treated object.Such as model is that the nominal output parameter of the laser therapeutic apparatus of MDC-500-I is as follows: output 0-500mW continuously adjustabe, laser spot diameter 50mm.But laser beam irradiation, to there is significant reflection and scattering during human body skin, causes effective laser power obviously to decline.
Known in sum, Measurement accuracy is very necessary with the parameter of control laser, but this point ignores in most clinical trial, and have very large individual variation to the reflection of laser and scattering ratio due to human body skin, be therefore necessary very much treating the demarcation all carrying out effective laser power each time in low power laser therapeutic process.Therefore need badly and set up laser parameter actual measurement means, in quantitative measurement treatment, arrive the effective laser parameter of affected part body surface, for suitable laser parameter scope is determined in low power laser treatment, and develop the laser parameter monitoring auxiliary facilities in the treatment of clinical low power laser.
[summary of the invention]
The object of the invention is for deficiency of the prior art, a kind of laser therapeutic apparatus reflected light and detector for scattered light are provided.
Of the present invention again one object be that a kind of method of demarcating the effective laser power of low power laser therapeutic instrument is provided.
Another object of the present invention provides described laser therapeutic apparatus reflected light and the purposes of detector for scattered light.
For achieving the above object, the technical scheme that the present invention takes is:
A kind of laser therapeutic apparatus reflected light and detector for scattered light, it is provided with detecting head, data acquisition unit and computer; Described detecting head is provided with photodiode and pre-amplifying module; Described data acquisition unit comprises data collecting card and power supply; Described data collecting card connects pre-amplifying module, and the analogue signal by photodiode collection and via pre-amplifying module output is converted to digital signal, and transfers data to computer, completes date processing in a computer; Described power supply connects pre-amplifying module, is responsible for pre-amplifying module and powers.
The number of described photodiode is 20.
Photodiode described under using state is arranged at the laser head surrounding volume of laser therapeutic apparatus, for accepting laser-bounce in backward nearly 180 degree of the laser head beam direction of laser therapeutic apparatus and scattered power signal.
Described photodiode is fan-shaped being uniformly distributed, the incident laser radiation window of laser head is equivalent to the vacancy of two photodiodes, the angle of the photodiode of the nearly coplanar laser illumination of incident laser radiation window side is 5 °, and the angle of the photodiode of the nearly coplanar laser illumination of incident laser radiation window opposite side is 170 °.
For realizing above-mentioned second object, the technical scheme that the present invention takes is:
Demarcate a method for the effective laser power of low power laser therapeutic instrument, comprise the following steps:
A) as above arbitrary described laser therapeutic apparatus reflected light and detector for scattered light are arranged on laser therapeutic apparatus front end, ensure that photodiode can accept the rear to the laser in nearly 180 degree of the laser head beam direction of laser therapeutic apparatus in the laser head surrounding volume arrangement of laser therapeutic apparatus;
B) all photodiodes are calibrated to identical amplification via the output of pre-amplifying module;
C) coefficient between the analogue signal that exports via pre-amplifying module of alignment light electric diode and laser power;
D) start low power laser therapeutic instrument, obtained effective laser power of low power laser therapeutic instrument by detecting head, data acquisition unit and computer.
Step b) concrete grammar be: each photodiode be correspond to same light source, records the output signal of each photodiode via pre-amplifying module, then calculate corresponding amplification and correct.
Step c) concrete grammar be: the laser of laser therapeutic apparatus is incided on one block of clouded glass, and an energy meter record transmitted optical power is placed after clouded glass, the photodiode of reflectance to be corrected is placed on the position of energy meter, utilizes the transmitted optical power alignment light electric diode of record.
For realizing above-mentioned 3rd object, the technical scheme that the present invention takes is:
As above arbitrary described laser therapeutic apparatus reflected light and detector for scattered light are demarcating the application in the effective laser power of low power laser therapeutic instrument.
The invention has the advantages that:
The present invention has following innovative point: the present invention establishes laser parameter actual measurement means, have developed laser therapeutic apparatus reflected light and detector for scattered light, and first passage monitoring laser backscatter and reflected signal obtain the accurately effective laser power entering body surface.The method that the present invention proposes can be widely used in practical function in low power laser therapeutic process in the quantitative measurement of effective laser power being treated object, to comparing and judging that the curative effect that low power laser is treated has very large meaning, be expected to the dispute of clarifying long-standing low power laser treatment curative effect, and suitable laser parameter can be determined for low-power treatment, being expected to the clinical auxiliary facilities developing into practical low power laser therapeutic instrument, selecting suitable parameters to provide important means for implementing personalized medicine for individual variation in the future.
[accompanying drawing explanation]
Accompanying drawing 1 is the structural representation of laser therapeutic apparatus reflected light of the present invention and detector for scattered light.
Accompanying drawing 2 is ultimate principle figure of laser therapeutic apparatus reflected light of the present invention and detector for scattered light.
Accompanying drawing 3 is using state schematic diagrams of laser therapeutic apparatus reflected light of the present invention and detector for scattered light.
Accompanying drawing 4 and Fig. 5 are the coefficient calibration schematic diagrams between the analogue signal of photodiode and laser power.
Accompanying drawing 6 is laser reflectivity (or reflection coefficient) results to 30 routine CTS patient's wrist actual measurements.
[detailed description of the invention]
Below in conjunction with accompanying drawing, detailed description of the invention provided by the invention is elaborated.
The Reference numeral related in accompanying drawing and ingredient as follows:
1. detecting head 11. photodiode
12. pre-amplifying module 2. data acquisition units
21. data collecting card 22. power supplys
3. computer 4. laser head
5. clouded glass 6. energy meter
Embodiment 1 laser therapeutic apparatus reflected light of the present invention and detector for scattered light
Please refer to Fig. 1, Fig. 1 is the structural representation of laser therapeutic apparatus reflected light of the present invention and detector for scattered light.Described laser therapeutic apparatus reflected light and detector for scattered light are provided with detecting head 1, data acquisition unit 2 and computer 3.Described detecting head 1 comprises 20 photodiodes 11 and pre-amplifying module 12, described photodiode 11 is connected with pre-amplifying module 12, and the output current signal of photodiode 11 is converted to 0-10V voltage signal by described pre-amplifying module 12.Described data acquisition unit 2 comprises data collecting card 21 and power supply 22.Described data collecting card 21 connects pre-amplifying module 12, and the analogue signal that pre-amplifying module 12 exports is converted to digital signal, and transfers data to computer 3, in computer 3, complete date processing.Described power supply 22 connects pre-amplifying module 12, is responsible for pre-amplifying module 12 and powers.Described computer 3 is provided with signal acquiring system, control system, Data Analysis Services system.
It should be noted that, when described photodiode 11 uses, its laser head surrounding volume at laser therapeutic apparatus is arranged, the laser power signal in backward nearly 180 degree of the laser head beam direction for accepting laser therapeutic apparatus; Described data collecting card 21 can be usb data capture card, as NI USB-6210, for receiving signal that each photodiode 11 exports via pre-amplifying module 12 and being transferred to computer 3; Described computer 3 is for calculating all reflections and scattering laser power total value; Described pre-amplifying module 12 is converted to 0-10V voltage signal for the current signal exported by photodiode 11, is convenient to subsequent acquisition and obtains.Described signal acquiring system, control system, Data Analysis Services system are for gathering, storing and analyze the various information (comprising the reflectance of different angles) of patient, facilitate the follow-up information tracing to patient and historical data process, these systems are known to those skilled in the art.
Embodiment 2 the present invention demarcates the method for the effective laser power of low power laser therapeutic instrument
Please refer to Fig. 2, Fig. 2 is the ultimate principle figure of laser therapeutic apparatus reflected light of the present invention and detector for scattered light.The ultimate principle of the inventive method is: because the laser beam irradiation launched of laser head scattering occurs to after scattering surface (skin) in space ± 90 °, 16 photodiodes 11 (using for testing for other 4) are distributed on one perpendicular in the cross section of scattering surface, the laser-bounce performance number that each photodiode 11 gathers is as the mean power of its place endless belt, then operated the laser-bounce power obtained in whole space by filtering, matching and weighting etc., judge that different skin is to sharp light reflectance with this.
As shown in Figure 2, 20 photodiodes 11 (wherein the power of 4 photodiodes detections of lowermost end extremely low can) are uniformly distributed in fan-shaped at grade, the angle of adjacent two photodiodes 11 is 7.86 °, because top needs for incident laser leaves illumination window, therefore top has two photodiode vacancies, the angle of first photodiode in right side is 5 ° (the anticlockwise angles relative to coplanar laser illumination), the angle of first photodiode in left side is 170 ° (the anticlockwise angles relative to coplanar laser illumination), then total angle is configured to 21 × 7.86 ° of+5 ° of+10 ° of ≈ 180 °, substantially whole hemisphere can be covered.
The calculation procedure of laser reflectivity is as follows:
1. filtering: for the electronic noise of filtering detecting head 1 and data acquisition unit 2, filtering method has many, determines to adopt frequency domain filtering method, filter away high frequency noise according to the measuring characteristic (acquisition rate is slower) of native system.
2. calibrate: because the parameter such as enlargement ratio, light sensitivitys of each photodiode 11 there are differences, therefore need first each photodiode 11 to be calibrated to identical amplification via the output of pre-amplifying module 12, suppose that each photodiode 11 is V via the voltage signal that pre-amplifying module 12 exports
i, calibration factor is e
i, then the numerical value after calibration is e
iv
i.
3. matching: because the restriction in space, top has two photodiode vacancies, and because the inhomogeneities of reflected light may cause the detectable signal of certain photodiode high especially or low especially, therefore need to carry out curve fitting to inverse signal, obtain the value of each photodiode (comprising the photodiode of 2 vacancies).Approximating method can adopt fitting of a polynomial, spline curve fitting, and least square fitting etc., can be competent at the simple curve of native system, this programme adopts fitting of a polynomial.Data after matching are:
m is multinomial exponent number, and a is the multinomial coefficient of matching.
4. weighted integral: the data measured by each photodiode 11 represent the meansigma methods of 7.68 ° of spherical zones at its place, and the area of each spherical zone is different, therefore needs the data to each photodiode 11 detects to be weighted integration.The areal calculation formula of spherical zone is:
Wherein, R is the radius of photodiode place sphere, and θ is the angle (θ=5 °+i* δ) of photodiode arrangement, and δ is the angle of spherical zone, δ=7.86 ° in native system.As can be seen from the above equation, the area of spherical zone only with | cos θ | relevant, the data therefore after weighting can be expressed as:
5. power transfer: treated data are before converted to final power signal.Owing to having carried out calibration and weighting to the signal of each photodiode before, as long as be therefore multiplied by a fixing coefficient to data before and summation just can obtain power signal.Therefore final reflected optical power can be expressed as:
Coefficient wherein between the c analogue signal that to be photodiode 11 export via pre-amplifying module 12 and laser power, n is the quantity (n=22) of detector.The bearing calibration of c is provided by next joint.
Please refer to Fig. 3, Fig. 3 is the using state schematic diagram of laser therapeutic apparatus reflected light of the present invention and detector for scattered light.During use, laser therapeutic apparatus reflected light of the present invention and detector for scattered light being directly installed on existing laser therapeutic apparatus front end, without the need to transforming laser therapeutic apparatus, and being only connected with common computer by USB line, there is the suitability and the strong feature of portability.The concrete grammar demarcating the effective laser power of low power laser therapeutic instrument is:
(1) all photodiodes 11 are calibrated to identical amplification via the output of pre-amplifying module 12
All photodiodes 11 to be calibrated to identical amplification via the output of pre-amplifying module 12, need the light source of a stable and uniform, and the stability that the sun has artificial light sources incomparable as the supplier of nature energy, uniformity, therefore can select a sunny daytime, all photodiodes 11 are placed in one plane, and aim at the sun, now be equivalent to each photodiode 11 and correspond to same light source, record the output signal of each photodiode 11 via pre-amplifying module 12, then can calculate corresponding amplification and correct.
(2) coefficient between the analogue signal that exports via pre-amplifying module 12 of alignment light electric diode 11 and laser power
See Fig. 4 and Fig. 5, the laser of laser therapeutic apparatus is incided on one block of clouded glass 5, and a placement energy meter 6 records transmitted optical power (as far as possible need select photosurface near the energy meter of front surface) after clouded glass; The detector of reflectance to be corrected is placed on the position of energy meter 6, utilizes the transmitted optical power calibration detectors of record.
(3) start low power laser therapeutic instrument, obtained effective laser power of low power laser therapeutic instrument by detecting head, data acquisition unit and computer.
Laser therapeutic apparatus reflected light of the present invention and detector for scattered light use 16 photodiodes for detection of reflected luminous power in whole reflection space, have higher accuracy.
Embodiment 3 application example
Apply laser therapeutic apparatus reflected light of the present invention and detector for scattered light and accept the wrist of the CTS patient of low power laser treatment in clinical middle actual measurement 30 to the reflectance of laser therapeutic apparatus Output of laser, to verify its implementation result.
Concrete laser therapeutic apparatus reflected light and detector for scattered light are configured to: laser therapeutic apparatus reflected light of the present invention and detector for scattered light are directly fixed on existing laser therapeutic apparatus (model that upper Heyman Di Sen Photoelectric Co., Ltd. produces is MDC-500-I Pain Therapy by Laser Diode instrument), described photodiode 11 specifically adopts the S2386-18K photodiode of Bin Song company, and its parameter is as shown in table 1.Photodiode is connected with pre-amplifying module, and photodiode output current signal is converted to 0-10V voltage signal by pre-amplifying module, is convenient to subsequent acquisition and obtains.Described data collecting card 21 specifically uses USB capture card (NI USB-6210), and its parameter is as shown in table 2.Original Output of laser head of removing laser therapeutic apparatus, the overall dimensions of detecting head is about: 172mm × 62mm × 40mm.
Table 1 photodiode parameter
■ General ratings/Absolute maximum ratings
■ Electrical and optical characteristics(Typ.Ta＝25℃，unless otherwise noted)
The parameter of table 2 USB capture card
Laser therapeutic apparatus reflected light of the present invention and detector for scattered light is calibrated according to the method for embodiment 2, support the use with the laser therapeutic apparatus of commercialization, by the clinical measurement of 30 examples, find that patient individual difference is very remarkable, the proportional difference of the output of effective laser irradiation power and laser therapeutic apparatus is very large, laser-bounce coefficient wide fluctuations between 1.32%-53.95% of actual measurement, as shown in Figure 6.Absolutely prove that the important evidence of the laser therapy Outcome measure that the present invention proposes first is the effective importance of this thinking of laser power of actual measurement and the novelty of the inventive method and feasibility.
The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the prerequisite not departing from the inventive method; can also make some improvement and supplement, these improve and supplement and also should be considered as protection scope of the present invention.
Claims (8)
1. laser therapeutic apparatus reflected light and a detector for scattered light, is characterized in that, it is provided with detecting head, data acquisition unit and computer; Described detecting head is provided with photodiode and pre-amplifying module; Described data acquisition unit comprises data collecting card and power supply; Described data collecting card connects pre-amplifying module, and the analogue signal by photodiode collection and via pre-amplifying module output is converted to digital signal, and transfers data to computer, completes date processing in a computer; Described power supply connects pre-amplifying module, is responsible for pre-amplifying module and powers.
2. laser therapeutic apparatus reflected light according to claim 1 and detector for scattered light, is characterized in that, the number of described photodiode is 20.
3. laser therapeutic apparatus reflected light according to claim 2 and detector for scattered light, it is characterized in that, photodiode described under using state is arranged at the laser head surrounding volume of laser therapeutic apparatus, for accepting the laser power signal in backward nearly 180 degree of the laser head beam direction of laser therapeutic apparatus.
4. laser therapeutic apparatus reflected light according to claim 3 and detector for scattered light, it is characterized in that, described photodiode is fan-shaped being uniformly distributed, the incident laser radiation window of laser head is equivalent to the vacancy of two photodiodes, the angle of the photodiode of the nearly coplanar laser illumination of incident laser radiation window side is 5 °, and the angle of the photodiode of the nearly coplanar laser illumination of incident laser radiation window opposite side is 170 °.
5. demarcate a method for the effective laser power of low power laser therapeutic instrument, it is characterized in that, comprise the following steps:
A) arbitrary for claim 1-4 described laser therapeutic apparatus reflected light and detector for scattered light are arranged on laser therapeutic apparatus front end, ensure that photodiode also can accept the rear to the laser power signal in nearly 180 degree of the laser head beam direction of laser therapeutic apparatus in the laser head surrounding volume arrangement of laser therapeutic apparatus;
B) all photodiodes are calibrated to identical amplification via pre-amplifying module output;
C) coefficient between the analogue signal that exports via pre-amplifying module of alignment light electric diode and laser power;
D) start low power laser therapeutic instrument, obtained effective laser power of low power laser therapeutic instrument by detecting head, data acquisition unit and computer.
6. method according to claim 5, it is characterized in that, step b) concrete grammar be: each photodiode be correspond to same light source, records the output signal of each photodiode via pre-amplifying module, then calculate corresponding amplification and correct.
7. method according to claim 5, it is characterized in that, step c) concrete grammar be: the laser of laser therapeutic apparatus is incided on one block of clouded glass, and an energy meter record transmitted optical power is placed after clouded glass, the photodiode of reflectance to be corrected is placed on the position of energy meter, utilizes the transmitted optical power alignment light electric diode of record.
8. the arbitrary described laser therapeutic apparatus reflected light of claim 1-4 and detector for scattered light are demarcating the application in the effective laser power of low power laser therapeutic instrument.
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| CN112445168A (en) * | 2020-11-27 | 2021-03-05 | 南京亿高微波系统工程有限公司 | Power correction system and method for semiconductor laser therapeutic instrument |
| CN116107194A (en) * | 2023-04-13 | 2023-05-12 | 北京新科以仁科技发展有限公司 | Automatic switching control method, device and equipment of laser and storage medium |
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| CN116107194B (en) * | 2023-04-13 | 2023-06-09 | 北京新科以仁科技发展有限公司 | Automatic switching control method, device and equipment of laser and storage medium |
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