CN104399023A - Traditional Chinese medicine composition for treating dysmenorrheal caused by cold-damp stagnation - Google Patents

Traditional Chinese medicine composition for treating dysmenorrheal caused by cold-damp stagnation Download PDF

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CN104399023A
CN104399023A CN201410623246.4A CN201410623246A CN104399023A CN 104399023 A CN104399023 A CN 104399023A CN 201410623246 A CN201410623246 A CN 201410623246A CN 104399023 A CN104399023 A CN 104399023A
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张鹏
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/89Cyperaceae (Sedge family)
    • A61K36/8905Cyperus (flatsedge)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention discloses a drug, and especially discloses a traditional Chinese medicine composition for treating dysmenorrheal caused by cold-damp stagnation. The traditional Chinese medicine composition is characterized by being composed of the following components in parts by weight: 6 to 9 parts of fennel, 6 to 9 parts of dry ginger, 6 to 12 parts of cassia twig, 10 to 12 parts of corydalis tuber, 6 to 9 parts of myrrh, 10 to 20 parts of rhizoma atractylodis, 15 to 30 parts of poria cocos, 10 to 20 parts of Chinese angelica, 10 to 15 parts of ligusticum wallichii, 6 to 9 parts of cassia bark, 6 to 9 parts of aspongopus, 6 to 9 parts of monkshood, 10 to 20 parts of folium artemisiae argyi, 20 to 30 parts of amethyst, 6 to 9 parts of common fenugreek seed, 10 to 15 parts of lindera aggregata, and 10 to 15 parts of cyperus rotundus. The traditional Chinese medicine composition can relieve the symptoms by warming the channel, relieving the pain, activating blood circulation, and removing the stasis, and thus treats the dysmenorrheal. The curative effect is prominent, and the life quality of patients is improved. The traditional Chinese medicine composition has the advantages of good curative effect, quick effect, and no side effect, and the effective rate can reach 98%.

Description

A kind of Chinese medicine composition for the treatment of cold and stagnate type dysmenorrhea
Technical field
The present invention relates generally to the field of Chinese medicines, particularly relates to a kind of Chinese medicine for the treatment of cold and stagnate type dysmenorrhea.
Background technology
Dysmenorrhea is women in menstrual period or before and after passing through, in a kind of gynaecopathia of few abdomen and waist generation pain, also known as " abdominal pain during menstruation ".The lighter's waist abdomen pain, severe one severe pain unbearably, moans ceaselessly, pale complexion, deadly cold hand and foot, dizzy tending to vomit.Causing very large misery to women's physical and mental health, is one of common gynecological disease.
The many invasions because being subject to cold, dampness of cold and stagnate type dysmenorrhea, the environment of daily life, work is often moist sombre, or sometimes hot and sometimes cold, and tie under causing cold, dampness can not smooth and easyly be drained, and forms the symptom of blood stasis.Show as premenstrual or cold-type pain in the lower abdomen during menstruation, meeting cold, humidity will increase the weight of, and likes warm pain relieved by pressing, obtains warm alleviation of pain, few through the light amount of color, with waist soreness, and the hands and feet being not warm, clear urine in large amounts etc.Body of the tongue purple is dim, or has ecchymosis, petechia, and tongue fur is white or greasy, stringy pulse or heavy tight.
The medicine of current treatment dysmenorrhea, doctor trained in Western medicine is that primary and secondary effect is large with therapies such as analgesia, calm, spasmolytic and hormone preparations substantially, needs Long-term taking medicine, easily produces toleration, cure the symptoms, not the disease, easily repeatedly, and lack specially for the medicine of cold and stagnate type dysmenorrhea.Traditional Chinese Medicine emphasizes the advantages such as organic conception, regulating yin and yang, treating both the principal and secondary aspects of a disease, toxic and side effects are little owing to having, and is more and more approved by people.
Summary of the invention
The object of the invention is exactly the defect in order to make up prior art, provides a kind of Chinese medicine composition of special for treating cold and stagnate type dysmenorrhea, and it is obvious for treatment cold and stagnate type dysmenorrhea curative effect, and safe ready, side effect is little.
The present invention is achieved by the following technical solutions:
Treat a Chinese medicine composition for cold and stagnate type dysmenorrhea, it is characterized in that: the weight proportion of each raw material is: Fructus Foeniculi 6-9, Rhizoma Zingiberis 6-9, Ramulus Cinnamomi 6-12, Rhizoma Corydalis 10-12, Myrrha 6-9, Rhizoma Atractylodis 10-20, Poria 15-30, Radix Angelicae Sinensis 10-20, Rhizoma Chuanxiong 10-15, Cortex Cinnamomi 6-9, Aspongopus 6-9, Radix Aconiti Lateralis Preparata 6-9, Folium Artemisiae Argyi 10-20, Fluoritum 20-30, Semen Trigonellae 6-9, Radix Linderae 10-15, Rhizoma Cyperi 10-15.
Treat a Chinese medicine composition for cold and stagnate type dysmenorrhea, it is preferably: the weight proportion of each raw material is: Fructus Foeniculi 8, Rhizoma Zingiberis 8, Ramulus Cinnamomi 10, Rhizoma Corydalis 12, Myrrha 8, Rhizoma Atractylodis 12, Poria 20, Radix Angelicae Sinensis 16, Rhizoma Chuanxiong 12, Cortex Cinnamomi 8, Aspongopus 8, Radix Aconiti Lateralis Preparata 8, Folium Artemisiae Argyi 15, Fluoritum 24, Semen Trigonellae 8, the Radix Linderae 12, Rhizoma Cyperi 12.
Compound method of the present invention is as follows: medicinal cold water soak in above-mentioned decocted after 1 hour, decocts moisture content and exceedes Chinese medicine 2-3 centimetre, with slow fire boiling 50 minutes after water boiling, filters and pours out medicinal liquid.Divide sooner or later, twice on the one.
detailed description of the invention:
Treat a Chinese medicine composition for cold and stagnate type dysmenorrhea, it is preferably: the weight proportion of each raw material is: Fructus Foeniculi 8g, Rhizoma Zingiberis 8g, Ramulus Cinnamomi 10g, Rhizoma Corydalis 12g, Myrrha 8g, Rhizoma Atractylodis 12g, Poria 20g, Radix Angelicae Sinensis 16g, Rhizoma Chuanxiong 12g, Cortex Cinnamomi 8g, Aspongopus 8g, Radix Aconiti Lateralis Preparata 8g, Folium Artemisiae Argyi 15g, Fluoritum 24g, Semen Trigonellae 8g, Radix Linderae 12g, Rhizoma Cyperi 12g.
Take the raw material components of above correspondence group, according to the routine fashion of decoction, add water and boil decoction and take.Divide sooner or later, twice on the one.
clinical observation:
Physical data:
(1) cold and stagnate card symptom weight hierarchical table:
(2) severity extent grade scale:
Comprehensive above-mentioned symptom, sign are marked, to judge severity extent.
Slight: symptom, somatic feature score and <8 divide.
Moderate: symptom, somatic feature score and 8 ~ 14 points.
Severe: symptom, somatic feature score and >14 divide.
(3) efficacy assessment standard:
The present invention is mainly used in cold and stagnate type dysmenorrhea, therefore with the improvement situation of dysmenorrhea symptom and degree for efficacy assessment standard, is divided into following four kinds:
Cure: after treatment, abdominal pain during menstruation disappears, and dysmenorrhea symptom integral reduces >=90%; After drug withdrawal, 3 menstrual cycle do not recur.
Effective: after treatment, abdominal pain during menstruation obviously alleviates, dysmenorrhea symptom integral reduces by >=70%, <90%.
Effective: after treatment, abdominal pain during menstruation alleviates, dysmenorrhea symptom integral reduces by >=30%, <70%.
Invalid: after treatment, abdominal pain during menstruation is without improving or increasing the weight of, and dysmenorrhea symptom integral reduces <30%.
The present inventor, year May in January, 2012 to 2014, carries out clinical observation treatment to 200 routine patients.According to " Chinese medical disease Standardization of diagnosis and curative effect ", be diagnosed as cold and stagnate type dysmenorrhea.Wherein severe person 16 example, moderate person 86 example, slight person 98 example.
(4) Therapeutic Method:
With medicine soak by water taking liquid of the present invention, monthly premenstrually serve on 7 doses, medical treatment continues 3 menstrual cycle, with consolidate curative effect.
(5) therapeutic effect:
clinical cure 132 example, effective 54 examples, effective 10 examples, invalid 4 examples, all cases all have no adverse reaction.
(6) sum up: effective percentage 98%, cure rate 66%.
The present invention is by antalgic, and blood circulation promoting and blood stasis dispelling, improves symptom, reaches the effect for the treatment of dysmenorrhea.Fructus Foeniculi in side, dispersing cold for relieving pain, regulating qi-flowing for harmonizing stomach, invigorate blood circulation, promoting the circulation of QI, pain relieving; Rhizoma Zingiberis, warming middle-JIAO is by cold, and recuperating depleted YANG is promoted blood circulation, and controls trusted subordinate's cold type of pain, vomits and diarrhoea, cold extremities faint pulse, and cold is breathed with cough, anemofrigid-damp arthralgia, and yang deficiency is told, be defeated in battle, hematochezia; Ramulus Cinnamomi, can dispelling cold by warming the meridian, diuretic dehumidifying, the logical yang-energy all over the body of temperature, smooth blood vessels all over the body, and regulating menstruation can lead to the stasis of blood; Rhizoma Corydalis, promoting blood circulation to remove blood stasis, regulating QI to relieve pain, " Bencao Jingshu " is said: Rhizoma Corydalis, and Wen Zeneng is with smooth, and freely then gas is capable; Xin Zeneng profit and wander away, wander away then blood live, blood lively atmosphere row, thus can main removing blood stasis and puerperal all cause of disease blood person of doing; Myrrha, loose blood detumescence, analgesic therapy granulation promoting; Rhizoma Atractylodis, drying damp and strengthening spleen, expelling wind and cold, improving eyesight; Poria, promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming; Radix Angelicae Sinensis, enriches blood and invigorates blood circulation, menstruction regulating and pain relieving, moisturizes laxation; Rhizoma Chuanxiong, blood-activating and qi-promoting, wind-expelling pain-stopping; Cortex Cinnamomi, complement sun, warming the spleen and stomach, removing accumulated cold, promoting blood circulation; Aspongopus, regulating QI to relieve pain, warming middle-JIAO are supporing yang; Radix Aconiti Lateralis Preparata, recuperating depleted YANG and rescuing the patient from collapse, warming and recuperating the spleen and kidney, dispersing cold for relieving pain; Folium Artemisiae Argyi, blood of regulating the flow of vital energy, by cold-damp, warming the meridian, hemostasis, antiabortive; Fluoritum, relieving palpitation, calm the nerves, lowering the adverse flow of QI, warm uterus; Semen Trigonellae, warming the kidney to activate YANG, dispersing cold for relieving pain; The Radix Linderae, warming kidney for dispelling cold, promoting the circulation of QI to relieve pain, opens breast resolving depression ;rhizoma Cyperi, resolving depression of regulating the flow of vital energy, pain relieving regulating menstruation.It is evident in efficacy, significantly reduces patient suffering, and relapse rate obviously declines, and improves the quality of life of patient, and has no side effect, and patient can feel at ease to take.Chinese medicine of the present invention, good effect, instant effect, has no side effect, and effective percentage reaches 98%.
For proving that the present invention has good curative effect, enumerate model case as follows:
Case 1.
Zhang, female, 34 years old, office worker, on January 18th, 2012 examined.Abdominal pain during menstruation more than 2 years, existing menstrual onset the 2nd day, few abdomen pain is obvious, companion's nausea and vomiting, the hands and feet being not warm, cold physique is timid cold, and lumbago heavily falls, and menstruation is not smooth not well, and color is dim, and clot amount is many, deep pulse stringy and tense pulse, light red tongue, white and greasy fur, indentations at the margin of the tongue, tcm diagnosis: dysmenorrhea (cold and stagnate type).With decoction medical treatment of the present invention, serve on 7, every day twice, advise continue through the last week next time and take 7.On February 15 two examined, and menstrual onset has no obvious stomachache, turns red through color, without clot, passed through 5 days totally, had no stomachache.Follow up a case by regular visits to 3 months, menstrual cycle is 28 days, red menses, and 5 days clean, and stomachache has no recurrence.
Case 2.
Liu, female, 23 years old, office worker, on August 14th, 2013, passed through and comes to go to a doctor for second day, cold and pain in the lower abdomen, the pain of pressing very, hypomenorrhea, menses are dark red clot, aversion to cold and cold limbs, complexion white, dimly red tongue, tongue is white, deep pulse stringy and tense pulse, former summer blows air-conditioning more, caused by drenching with rain proper menstrual period last time.The diagnosis and treatment of Zeng Qu community hospital, are diagnosed as dysmenorrhea, give treatment effect of indomethacin, poor effect.Tcm diagnosis: dysmenorrhea (cold and stagnate type).With decoction medical treatment of the present invention, serve on 7, every day twice, advise continue through the last week next time and take 7.Further consultation subsequently, recovery from illness.

Claims (2)

1. treat a Chinese medicine composition for cold and stagnate type dysmenorrhea, it is characterized in that: the weight proportion of each raw material is: Fructus Foeniculi 6-9, Rhizoma Zingiberis 6-9, Ramulus Cinnamomi 6-12, Rhizoma Corydalis 10-12, Myrrha 6-9, Rhizoma Atractylodis 10-20, Poria 15-30, Radix Angelicae Sinensis 10-20, Rhizoma Chuanxiong 10-15, Cortex Cinnamomi 6-9, Aspongopus 6-9, Radix Aconiti Lateralis Preparata 6-9, Folium Artemisiae Argyi 10-20, Fluoritum 20-30, Semen Trigonellae 6-9, Radix Linderae 10-15, Rhizoma Cyperi 10-15.
2. Chinese medicine composition as claimed in claim 1, is characterized in that: the weight proportion of each raw material is: Fructus Foeniculi 8, Rhizoma Zingiberis 8, Ramulus Cinnamomi 10, Rhizoma Corydalis 12, Myrrha 8, Rhizoma Atractylodis 12, Poria 20, Radix Angelicae Sinensis 16, Rhizoma Chuanxiong 12, Cortex Cinnamomi 8, Aspongopus 8, Radix Aconiti Lateralis Preparata 8, Folium Artemisiae Argyi 15, Fluoritum 24, Semen Trigonellae 8, the Radix Linderae 12, Rhizoma Cyperi 12.
CN201410623246.4A 2014-11-09 2014-11-09 Traditional Chinese medicine composition for treating dysmenorrheal caused by cold-damp stagnation Pending CN104399023A (en)

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CN105412571A (en) * 2015-12-29 2016-03-23 兖矿集团有限公司总医院 Medicine composition for treating cold-damp-stagnation primary dysmenorrhea in cooperation with milli-fire needles
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CN109276701A (en) * 2018-12-10 2019-01-29 李天基 A kind of pharmaceutical composition and preparation method thereof for treating dysmenorrhea
CN110841033A (en) * 2019-11-14 2020-02-28 河北中医学院 Traditional Chinese medicine health-care waistband for preventing and treating blood deficiency and cold coagulation type dysmenorrhea and preparation method thereof

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蒲继明等: "加味少腹逐瘀汤配合点穴治疗原发性痛经68例", 《陕西中医》 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105214048A (en) * 2015-10-30 2016-01-06 青岛申达高新技术开发有限公司 Be used for the treatment of the medicine of cold blood stasis type primary dysmenorrhea
CN105495291A (en) * 2015-11-30 2016-04-20 广东岭南职业技术学院 Black-bone chicken ravioli capable of regulating menstruation and preparation method for ravioli
CN105412571A (en) * 2015-12-29 2016-03-23 兖矿集团有限公司总医院 Medicine composition for treating cold-damp-stagnation primary dysmenorrhea in cooperation with milli-fire needles
CN109276701A (en) * 2018-12-10 2019-01-29 李天基 A kind of pharmaceutical composition and preparation method thereof for treating dysmenorrhea
CN110841033A (en) * 2019-11-14 2020-02-28 河北中医学院 Traditional Chinese medicine health-care waistband for preventing and treating blood deficiency and cold coagulation type dysmenorrhea and preparation method thereof

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Application publication date: 20150311