CN104398989A - Medicament for treating infertility and preparation method thereof - Google Patents
Medicament for treating infertility and preparation method thereof Download PDFInfo
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- CN104398989A CN104398989A CN201410703257.3A CN201410703257A CN104398989A CN 104398989 A CN104398989 A CN 104398989A CN 201410703257 A CN201410703257 A CN 201410703257A CN 104398989 A CN104398989 A CN 104398989A
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Abstract
The invention relates to a medicament for treating infertility and a preparation method thereof. The medicament is prepared from semen coicis, teasel root, red peony root, moutan bark, the seed of Chinese dodder, herba bupleurl, roasted amethyst, alcohol processed angelica sinensis diels, ligusticum chuanxiong hort, rhizoma atractylodis macrocephalae stir-fried with bran, the root of red-rooted salvia, red flower and cucuma powder through compatibility and has curative effects of nourishing liver and kidney, regulating blood vessel, promoting blood circulation for regulating menstruation, prompting pregnancy and benefiting maternal body and the like. The medicament has practical curative effects on diseases of female patients, such as irregular menstruation, amenorrhea and dysmenorrhea, threatened abortion, uterine bleeding, abnormal leukorrhea, uterine bleeding and descent of blood, heat attacking uterus, infertility caused by insufficiency-cold blood sea, blood stasis menstrual block, endometriosis, hypoplasia of uterus, habitual abortion and the like.
Description
Technical field
The present invention relates to a kind of is Chinese medicine composition of crude drug and preparation method thereof by Chinese herbal medicine, relates to a kind of medicine for the treatment of sterility and infertility and preparation method thereof specifically.
Background technology
Sterility and infertility is gynaecopathia common from ancient times to the present, reason numerous complicated, and the impact of many-sided unfavorable factor such as present contaminated grade, this is sick in increasing trend, so the medicine producing progestogenic is various, but its progestogenic function singleness, lack effect for the treatment of both the principal and secondary aspects of a disease, cause patient to step into mistaken ideas, until uncomfortable, sb.'s illness took a turn for the worse, fetal anomaly, habitual abortion abortion, infertile etc. all the life.
Summary of the invention
The present invention is directed to above-mentioned deficiency, propose one from clinical treatment medication demand and the dialectical principle of traditional Chinese medical science prescription and cure mainly sterility and infertility for many years, the compatible combination medicine of reproduction environment, blood stasis dispelling dredging in conditioning and manufacture method thereof.Medicine of the present invention is the medicament be prepared into by the raw material of following parts by weight proportioning:
Semen Coicis (parched) 8-12g, Radix Dipsaci 13-17g, Radix Paeoniae Rubra 10-14g, Cortex Moutan 8-12g, Semen Cuscutae 8-12g, HERBA BUPLEURL 6-10g, forge Fluoritum 2-5g, Radix Angelicae Sinensis (parched with wine) 8-12g, Rhizoma Chuanxiong 8-12g, Rhizoma Atractylodis Macrocephalae (parched with bran) 8-12g, Radix Salviae Miltiorrhizae 8-12g, Flos Carthami 6-10g, Radix Curcumae 10-14g.Optimum ratio is: Semen Coicis (parched) 10g, Radix Dipsaci 15g, Radix Paeoniae Rubra 12g, Cortex Moutan 10g, Semen Cuscutae 10g, HERBA BUPLEURL 8g, forge Fluoritum 3g, Radix Angelicae Sinensis (parched with wine) 10g, Rhizoma Chuanxiong 10g, Rhizoma Atractylodis Macrocephalae (parched with bran) 10g, Radix Salviae Miltiorrhizae 10g, Flos Carthami 8g, Radix Curcumae 12g.Described medicament is capsule, tablet or pill.
The preparation method step of described capsule, tablet, pill is as follows:
(1) Semen Coicis (parched), Radix Dipsaci, Radix Paeoniae Rubra, Cortex Moutan, Semen Cuscutae, HERBA BUPLEURL in the side of getting, forge Fluoritum, Radix Angelicae Sinensis (parched with wine), Rhizoma Chuanxiong, Rhizoma Atractylodis Macrocephalae (parched with bran), Radix Salviae Miltiorrhizae, Flos Carthami, Radix Curcumae pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry for step granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
Mixture described in step (2), the preferred number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
beneficial effect
Clinical practice for many years and test, confirm that medicine of the present invention has estrogenic activity, suppresses uterine myometrium and analgesia, improves ability effect of exempting from service.
Medicine for a better understanding of the present invention, as follows from pharmacodynamics angle analysis:
the present invention's each crude drug drug effect is as follows:
Semen Coicis (parched): sweet in the mouth, light, cool in nature.Return spleen, stomach, lung meridian.[function cures mainly] favourable water permeation wets, invigorating the spleen to arrest diarrhea, eliminating impediment, evacuation of pus, the effect of detoxicating and resolving stagnation of pathogens.For edema, beriberi, dysuria, diarrhea due to hypofunction of the spleen, arthralgia chiefly caused by damp pathogen contracture, lung abscess, intestinal carbuncle; Wart, cancerous protuberance.
Radix Dipsaci: [function cures mainly] invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating.Control aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, carbuncle skin ulcer swells.
Vitamin antagonist E deficiency disease: through white mice and chicken test, prove that Radix Dipsaci has the effect of vitamin antagonist E deficiency disease.
Hemostasis, analgesic activity: effect carbuncle and ulcer being had to evacuation of pus, hemostasis, analgesia, promotion tissue regeneration.Sexual impotence erectile problem, the seminal emission enuresis.Soreness of waist and knee joint, arthralgia due to cold-dampnes.Metrostaxis, frequent fetal movement.Traumatic injury, the injury of tendon and muscle is fractured.
Radix Paeoniae Rubra: bitter in the mouth, cold nature.Return Liver Channel.[function cures mainly] clearing away heat and cooling blood, eliminating stasis to stop pain.For thermal man's nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, addiction abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection.
Cortex Moutan: bitter, pungent, is slightly cold.GUIXIN, liver, kidney channel.[function cures mainly] clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.Thermal man's nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, falls and flutters the pain of injury, carbuncle sore tumefacting virus.
Semen Cuscutae: Gui Jing: abnormal smells from the patient is pungent, sweet, flat nontoxic.[function with cure mainly]: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity.The waist knee joint muscles and bones being applicable to deficiency of the liver and kindey is ached, the diseases such as legs and feet weakness, impotence and seminal emission, crazy talk, frequent micturition, dripping urination, dizziness and blurred vision, blurring of vision, Hiccough and deaf and women's leukorrhagia, habitual abortion.There is good yang invigorating functions: experiment proves: Semen Cuscutae is improved the effect of fruit bat Sexual potency, its mating rate is obviously increased, effect is strong and weak becomes positive correlation with administration concentration for it. to because of mice " yang deficiency " model caused by hydrocortisone, with its yang deficiency symptom can be made after Semen Cuscutae to have certain restitution, but fail to make animal return to levels found in normal controls.Experiment shows: Semen Cuscutae decocting liquid gives " yang deficiency " mouse stomach, and the vigor of its body weight, kidney weight, chest gland weight, leukocyte count, RBC number, hemoglobin and superoxide dismutase can be made significantly to increase; To male mice gavage, can the swimming time of significant prolongation mice and time-to-live under anoxic conditions, also there is potentiation to the nonspecific resistance of mice.
HERBA BUPLEURL: bitter, cool.Enter liver, gallbladder meridian.[function with cure mainly] is controlled yang-energy and is sunk, and suppressing the hyperactive liver, gallbladder, three burnt, envelope is mutually fiery, and headache, dizzy, and blurred vision, swelling pain are hidden from view, deaf ring, all malarias, and lump at the left hypochondrium cold and heat, married woman's invasion of the blood-chamber by heat, irregular menstruation, children's's varioliform exanthema waste heat, the thin heat of five kinds of child malnutrition.
Forge Fluoritum: sweet, temperature.Enter the heart, Liver Channel.[function with cure mainly] relieving palpitation, calms the nerves, lowering the adverse flow of QI, warm uterus.Control asthenia palpitation with fear, cough with dyspnea, women's sea of blood deficiency and coldness is infertile.
Radix Angelicae Sinensis (parched with wine): return liver, the heart, spleen channel.[function with cure mainly] enriches blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize laxation.The all cards of main blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.
Rhizoma Chuanxiong: pharmacopeia is included as Rhizoma Chuanxiong, often writes Rhizoma Chuanxiong in prescription.Rhizoma Chuanxiong is written as because of differences such as regional reason literary style customs.Have another name called large Rhizoma Chuanxiong, comfort vault, separately have wine Rhizoma Chuanxiong.Return liver, gallbladder, pericardium channel.[effect] blood-activating and qi-promoting, wind-expelling pain-stopping.Rhizoma Chuanxiong is apt to " lower regulating menstruation water, middle relieving stagnation ", is gynecological's key medicine, and energy promoting blood flow to regulate menstruation, the disease of department of obstetrics and gynecology is planted by available Zhiduo County.As controlled blood stasis amenorrhea, dysmenorrhea, be often equal to use with Radix Paeoniae Rubra, Semen Persicae, as decoction for removing blood stasis (errors in Medicine Corrected); If belong to cold blood stasis person, Cortex Cinnamomi, Radix Angelicae Sinensis etc. can be joined, as decoction for warming channels (" Complete Effective Prescriptions for Women "); If control lochiostasis, stasis blocking is suffered from abdominal pain, and can join Radix Angelicae Sinensis, Semen Persicae, Rhizoma Zingiberis Preparatum etc., as SHENGHUATANG ("Fu Qingzhu works on obstetric"); If control menoxenia, after preceded menstrual cycle or mistake, Herba Leonuri, Radix Angelicae Sinensis etc. can be joined, as Herba Leonuri wins Jindan (" Medicine Comprehended ").Stagnation of QI and blood pain card can be controlled.The pungent loose temperature of this product is led to, can blood circulation promoting and blood stasis dispelling, again can promoting the circulation of QI to relieve pain, is " the gas medicine in blood ", the sensible QI and blood effect of tool, therefore controls the breast side of body, all pains of abdominal part of qi depression to blood stasis.If control the obstruction of qi in the chest and cardialgia of heart arteries and veins stasis blocking, normal being equal to Radix Salviae Miltiorrhizae, Ramulus Cinnamomi, Lignum Santali Albi, is used; If control the hypochondriac pain of stagnation of QI due to depression of the liver, often join Radix Bupleuri, the Radix Paeoniae Alba, Rhizoma Cyperi, as bupleurum powder for relieving liver-qi (Jing-Yue Complete Works); As liver blood stasis, gather mass in the abdomen, the twinge of the breast side of body, how to be equal to use with Semen Persicae, Flos Carthami, as decoction for removing blood stasis (errors in Medicine Corrected).If control tumbling down damage, pain caused by ecchymoma, it is medicinal to join Olibanum, Myrrha, Radix Notoginseng etc.
Rhizoma Atractylodis Macrocephalae (parched with bran): burn heat in first being used by pot, be sprinkled into Testa Tritici.In time smoldering, drop into Rhizoma Atractylodis Macrocephalae sheet, constantly stir-frying, is coke yellow to the Rhizoma Atractylodis Macrocephalae, and effusion burnt odor gas, take out, sieve removes Testa Tritici, cools.Can dry property be relaxed, in entering by means of bran, strengthen spleen invigorating, detumescence effect.For incoordination between the spleen and stomach, dysfunction of the spleen in transportation and transformation, lack of appetite distension fatigue and weakness, exterior deficiency spontaneous perspiration.
Radix Salviae Miltiorrhizae: nature and flavor are bitter, are slightly cold.GUIXIN, Liver Channel.There is stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the effect of the relieving restlessness that clears away heart-fire.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Flos Carthami: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, contributes to controlling amenorrhea, dysmenorrhea, lochia, obstruction of qi in the chest and cardialgia, the stagnant stomachache of the stasis of blood, the twinge of the breast side of body, traumatic injury, skin infection swells and ache curative effect.Have blood circulation promoting and blood stasis dispelling, wet dissipation goes the effect swollen, and avoids anemia of pregnant woman to use, otherwise can cause miscarriage.
Radix Curcumae: acrid in the mouth, hardship, cold in nature.Return liver, the heart, lung meridian, there is the use of regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, promoting blood circulation and stopping pain, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire.
Medicine of the present invention is that folk prescription among the people combined with the modern times, is the goods of new generation that traditional decoction changes, has the curative effects such as invigorating the liver and kidney, blood circulation regulating, promoting blood flow to regulate menstruation, progestogenic Herba Leonuri.Show through clinical observation that medicine of the present invention is infertile to the menoxenia of female patient, amenorrhea dysmenorrhea, vaginal bleeding during pregnancy, metrorrhagia, leucorrhea abnormal, metrostaxis, invasion of the blood-chamber by heat, sea of blood deficiency and coldness, the disease such as blood stasis amenorrhea, endometriosis, uterine hypoplasia, habitual abortion has practical curative effect.
Medicine of the present invention is by clinical proof: in gynaecopathia, progestogenic, medicine of the present invention reaches 95 percent to treatment barrenness total effective rate, and processing method of the present invention is simple, flow process is few, reduce its cost, medicine of the present invention holds the marrow of the traditional Chinese medical science, rigorous prescription: strong muscle of enriching blood, loosening bowel to relieve constipation, caring skin, progestogenic Herba Leonuri; Removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving, abdominal mass of dispelling painful abdominal mass, antiabortively to compose oneself; Promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, along regulating the flow of vital energy, raw gram help mutually; All medicine monarch share, and mend broken combination, bring out the best in each other, meet the principle of traditional Chinese medical science medicine law and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.
Results of pharmacodynamic test shows: the present invention to two physical weakness, the soft waist of lower limb thanks to caused of QI and blood soft have benefiting action and can enrich blood, the dredging of menstruction regulating and pain relieving, dissipating blood stasis, progestogenic Herba Leonuri.
Estrogen-like effects: infant rats is filled with and fed medicine of the present invention, endometrium can be made to increase, the visible endometrial thickness of Microscopic observation, cell is in double-deck evenly distributed, glandular cell is more, volume is comparatively large, and in glandular secretion state, follicle is also progressively grown until ripe; Rat drinks medicine of the present invention, can maintain and extend the normal function of Alfasone cell;
Suppress uterine myometrium: medicine of the present invention can suppress pituitrin to the contraction of isolated uterine;
Spasmolytic effect: medicine of the present invention can reduce the number of times that lumbar injection acetic acid induced mice produces writhing response;
Strengthen immunocompetence: fill with and feed medicine of the present invention, the removing speed of normal mouse to carbon granules in blood and the amount of antibody forming cell can be improved, promote that B cell is by the division growth after antigenic stimulus, increases young Mus thymus index, strengthen the ability that Turnover of Mouse Peritoneal Macrophages engulfs chicken red blood cell;
Acute toxicity test: medicine of the present invention promotes hemoposieis, to acute bleeding model mice gavage medicine of the present invention, the recovery of erythrocyte and hemoglobin can be promoted, improve the content of hemoglobin, shorten mice bleeding time and blood plasma recalcification time, extend mice normal pressure and hypoxia death and walking weight load, toxicological test result of study shows, its anxious toxicity is very little, larger dose and take the growth to rat compared with long-term therapy, hemopoietic function is without remarkable toxicity, to the brain of rat, the heart, liver, lung, the chip form inspections such as kidney have no overt toxicity damage and change, prove its safety.
Detailed description of the invention
embodiment 1:a kind of medicine for the treatment of sterility and infertility and preparation method thereof.It is the medicament be prepared from by the crude drug of following parts by weight proportioning: Semen Coicis (parched) 8-12g, Radix Dipsaci 13-17g, Radix Paeoniae Rubra 10-14g, Cortex Moutan 8-12g, Semen Cuscutae 8-12g, HERBA BUPLEURL 6-10g, forge Fluoritum 2-5g, Radix Angelicae Sinensis (parched with wine) 8-12g, Rhizoma Chuanxiong 8-12g, Rhizoma Atractylodis Macrocephalae (parched with bran) 8-12g, Radix Salviae Miltiorrhizae 8-12g, Flos Carthami 6-10g, Radix Curcumae 10-14g.Described medicament is capsule, tablet or pill.
According to following portions by weight proportioning weighting raw materials:
Semen Coicis (parched) 8-12g, Radix Dipsaci 13-17g, Radix Paeoniae Rubra 10-14g, Cortex Moutan 8-12g, Semen Cuscutae 8-12g, HERBA BUPLEURL 6-10g, forge Fluoritum 2-5g, Radix Angelicae Sinensis (parched with wine) 8-12g, Rhizoma Chuanxiong 8-12g, Rhizoma Atractylodis Macrocephalae (parched with bran) 8-12g, Radix Salviae Miltiorrhizae 8-12g, Flos Carthami 6-10g, Radix Curcumae 10-14g.
The preparation method step of described capsule, tablet, pill is as follows:
(1) Semen Coicis (parched), Radix Dipsaci, Radix Paeoniae Rubra, Cortex Moutan, Semen Cuscutae, HERBA BUPLEURL in the side of getting, forge Fluoritum, Radix Angelicae Sinensis (parched with wine), Rhizoma Chuanxiong, Rhizoma Atractylodis Macrocephalae (parched with bran), Radix Salviae Miltiorrhizae, Flos Carthami, Radix Curcumae pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry for step granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
Mixture described in step (2), the preferred number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
embodiment 2:a kind of medicine for the treatment of sterility and infertility and preparation method thereof.It is the medicament be prepared from by the crude drug of following parts by weight proportioning: Semen Coicis (parched) 10g, Radix Dipsaci 15g, Radix Paeoniae Rubra 12g, Cortex Moutan 10g, Semen Cuscutae 10g, HERBA BUPLEURL 8g, forge Fluoritum 3g, Radix Angelicae Sinensis (parched with wine) 10g, Rhizoma Chuanxiong 10g, Rhizoma Atractylodis Macrocephalae (parched with bran) 10g, Radix Salviae Miltiorrhizae 10g, Flos Carthami 8g, Radix Curcumae 12g.Described medicament is capsule, tablet or pill.
According to following portions by weight proportioning weighting raw materials:
Semen Coicis (parched) 10g, Radix Dipsaci 15g, Radix Paeoniae Rubra 12g, Cortex Moutan 10g, Semen Cuscutae 10g, HERBA BUPLEURL 8g, forge Fluoritum 3g, Radix Angelicae Sinensis (parched with wine) 10g, Rhizoma Chuanxiong 10g, Rhizoma Atractylodis Macrocephalae (parched with bran) 10g, Radix Salviae Miltiorrhizae 10g, Flos Carthami 8g, Radix Curcumae 12g.
The preparation method step of described capsule, tablet, pill is as follows:
(1) Semen Coicis (parched), Radix Dipsaci, Radix Paeoniae Rubra, Cortex Moutan, Semen Cuscutae, HERBA BUPLEURL in the side of getting, forge Fluoritum, Radix Angelicae Sinensis (parched with wine), Rhizoma Chuanxiong, Rhizoma Atractylodis Macrocephalae (parched with bran), Radix Salviae Miltiorrhizae, Flos Carthami, Radix Curcumae pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry for step granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
Mixture described in step (2), the preferred number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
Embodiment 3, the dosage form of medicine of the present invention can also be granule, oral liquid, decoction.
Claims (5)
1. treat a medicine for sterility and infertility, it is characterized in that it is the medicament be prepared from by the crude drug of following parts by weight proportioning: Semen Coicis (parched) 8-12g, Radix Dipsaci 13-17g, Radix Paeoniae Rubra 10-14g, Cortex Moutan 8-12g, Semen Cuscutae 8-12g, HERBA BUPLEURL 6-10g, forge Fluoritum 2-5g, Radix Angelicae Sinensis (parched with wine) 8-12g, Rhizoma Chuanxiong 8-12g, Rhizoma Atractylodis Macrocephalae (parched with bran) 8-12g, Radix Salviae Miltiorrhizae 8-12g, Flos Carthami 6-10g, Radix Curcumae 10-14g.
2. the medicine for the treatment of sterility and infertility according to claim 1, is characterized in that it is the medicament be prepared from by the crude drug of following parts by weight proportioning: Semen Coicis (parched) 10g, Radix Dipsaci 15g, Radix Paeoniae Rubra 12g, Cortex Moutan 10g, Semen Cuscutae 10g, HERBA BUPLEURL 8g, forge Fluoritum 3g, Radix Angelicae Sinensis (parched with wine) 10g, Rhizoma Chuanxiong 10g, Rhizoma Atractylodis Macrocephalae (parched with bran) 10g, Radix Salviae Miltiorrhizae 10g, Flos Carthami 8g, Radix Curcumae 12g.
3. the medicine for the treatment of sterility and infertility according to claim 1 and 2, is characterized in that: described medicament is capsule, tablet or pill.
4. the medicine for the treatment of sterility and infertility according to claim 3, is characterized in that: the preparation method step of described capsule, tablet, pill is as follows:
(1) Semen Coicis (parched), Radix Dipsaci, Radix Paeoniae Rubra, Cortex Moutan, Semen Cuscutae, HERBA BUPLEURL in the side of getting, forge Fluoritum, Radix Angelicae Sinensis (parched with wine), Rhizoma Chuanxiong, Rhizoma Atractylodis Macrocephalae (parched with bran), Radix Salviae Miltiorrhizae, Flos Carthami, Radix Curcumae pulverize screen analysis;
(2) decocted with water 2-3 time by the mixture of sieve series in step (1), collecting decoction, filtration, worry liquid is condensed into 70-80 when spending, capsule, pill relative density are the thick paste of 1.0-1.6, and tablet relative density is the thick paste of 1.0-1.4;
(3) when making capsule, pill:
By thick paste separation and purification, drying, make dry granule; By dry for step granule mix homogeneously, in filled capsules, namely make capsule; Dry granule spray is added refined honey, mix homogeneously, makes piller and namely make pill;
When making tablet:
2-4 part starch is mixed homogeneously with the thick paste in step (2), makes granule, drying, make dry granule, dry granule is pressed into tablet, sugar coating, namely makes tablet.
5. the preparation method of the medicine for the treatment of sterility and infertility according to claim 4, is characterized in that the mixture described in step (2), and the number of times decocted with water is 2 times, and first time is 60-80 minute, and second time is 40-60 minute.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410703257.3A CN104398989A (en) | 2014-11-29 | 2014-11-29 | Medicament for treating infertility and preparation method thereof |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101780231A (en) * | 2010-03-22 | 2010-07-21 | 胡冠彬 | Traditional Chinese medicine for treating damp-heat infertility and preparation method thereof |
| CN102114221A (en) * | 2009-12-31 | 2011-07-06 | 李运乃 | Medicine for treating female infertility |
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- 2014-11-29 CN CN201410703257.3A patent/CN104398989A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102114221A (en) * | 2009-12-31 | 2011-07-06 | 李运乃 | Medicine for treating female infertility |
| CN101780231A (en) * | 2010-03-22 | 2010-07-21 | 胡冠彬 | Traditional Chinese medicine for treating damp-heat infertility and preparation method thereof |
Non-Patent Citations (1)
| Title |
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| 王肃季: "温经补肾活血化瘀治疗原发性不孕症15例临床体会", 《河北中医》 * |
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