CN104398576A - Traditional Chinese medicine preparation for treating cervical spondylosis as well as preparation method and application thereof - Google Patents

Traditional Chinese medicine preparation for treating cervical spondylosis as well as preparation method and application thereof Download PDF

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CN104398576A
CN104398576A CN201410786120.9A CN201410786120A CN104398576A CN 104398576 A CN104398576 A CN 104398576A CN 201410786120 A CN201410786120 A CN 201410786120A CN 104398576 A CN104398576 A CN 104398576A
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chinese medicine
medicine preparation
cervical spondylosis
treatment
radix
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朱静
赵兰
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Qingdao Bairuiji Biological Engineering Co Ltd
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Qingdao Bairuiji Biological Engineering Co Ltd
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237Notopterygium
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    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating cervical spondylosis. The traditional Chinese medicine preparation includes the following components by mass: 10-15 g of asarum, 5-8 g of notopterygium incisum, 5-8 g of scorpion, 10-12 g of caulis spatholobi, 5-8 g of tuberculate speranskia herb, 3-5 g of radix angelicae dahuricae, 3-5 g of ligusticum chuanxiong hort, 5-8 g of angelica sinensis, 3-5 g of semen strychni, 3-5 g of olibanum, 5-8 g of cassia twig, and 3-5 g of radix puerariae. Meanwhile, the invention further discloses a preparation method and application of the traditional Chinese medicine preparation. Through the medicinal values and the compatibility effect of all components in the traditional Chinese medicine preparation, the traditional Chinese medicine preparation has the effects of effectively eliminating cold and dampness, promoting blood circulation to remove meridian obstruction, calming the liver, fixing vertigo, relaxing the neck and refreshing, and has the advantages of good curative effect and low cost.

Description

Chinese medicine preparation being used for the treatment of cervical spondylosis and preparation method thereof and application
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof and application, especially a kind of Chinese medicine preparation for the treatment of cervical spondylosis and preparation method thereof and application, belong to Chinese medicine formula and applied technical field.
Background technology
Cervical spondylosis, also known as cervical vertebra syndrome, is osteoarthritis of cervical spine, proliferative cervical spondylosis, cervical nerve root syndrome, cervical intervertebral disk comes off the general name of disease.Main rise because the long-term strain of cervical vertebra, hyperosteogeny, or prolapse of intervertebral disc, ligament thickens, and causes cervical vertebra spinal cord, nerve root or cone tremulous pulse pressurized, and then occurs a series of handicapped clinical syndrome.At present, cervical spondylosis by original senile disease more and more to " rejuvenation ", " becoming younger " develop, many youngsters are due to work and occupational relation, need to bend over the desk for a long time, long-time " forcing " health keeps same posture, thus has buried the seed of trouble for occurred frequently and " rejuvenation " of cervical spondylosis.The great misery that cervical spondylosis is brought to patient, therefore severe patient even can patient paralyse, and therefore effectively treatment is most important.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide that a kind of side effect is little, good effect, expense are low, therapeutic effect be significantly used for the treatment of cervical spondylosis Chinese medicine preparation and preparation method thereof and application.
For solving the problems of the technologies described above, technical scheme of the present invention is:
The Chinese medicine preparation for the treatment of cervical spondylosis, is characterized in that, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively:
Herba Asari: 10-15g;
Rhizoma Et Radix Notopterygii: 5-8g;
Scorpio: 5-8g;
Caulis Spatholobi: 10-12g;
Herba speranskiae tuberculatae: 5-8g;
The Radix Angelicae Dahuricae: 3-5g;
Rhizoma Chuanxiong: 3-5g;
Radix Angelicae Sinensis: 5-8g;
Semen Strychni: 3-5g;
Olibanum: 3-5g;
Ramulus Cinnamomi: 5-8g;
Radix Puerariae: 3-5g.
Further, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively: Herba Asari: 15g; Rhizoma Et Radix Notopterygii: 5g; Scorpio: 5g; Caulis Spatholobi: 10g; Herba speranskiae tuberculatae: 5g; The Radix Angelicae Dahuricae: 5g; Rhizoma Chuanxiong: 5g; Radix Angelicae Sinensis: 5g; Semen Strychni: 5g; Olibanum: 5g; Ramulus Cinnamomi: 5g; Radix Puerariae: 5g.
Further, the described Chinese medicine preparation being used for the treatment of cervical spondylosis, also comprises Flos Carthami: 8-10g.
And the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively: Herba Asari: 15g; Rhizoma Et Radix Notopterygii: 5g; Scorpio: 5g; Caulis Spatholobi: 10g; Herba speranskiae tuberculatae: 5g; The Radix Angelicae Dahuricae: 5g; Rhizoma Chuanxiong: 5g; Radix Angelicae Sinensis: 5g; Semen Strychni: 5g; Olibanum: 5g; Ramulus Cinnamomi: 5g; Radix Puerariae: 5g; Flos Carthami 10g.
The above-mentioned manufacture method being used for the treatment of the Chinese medicine preparation of cervical spondylosis, it is characterized in that, after the described quality proportioning being used for the treatment of each component in the Chinese medicine preparation of cervical spondylosis is mixed, carry out pulverizing and grind to form fine powder, cross 80-100 mesh sieve, then the fine powder after sieving is dropped in mixing and blending machine and fully mix, and for subsequent use according to the metering, distributing, packaging of every agent.
And, the application of above-mentioned Chinese medicine preparation on preparation treatment cervical spondylosis medicine.
Beneficial effect of the present invention is: the present invention is by the medical value of each component in Chinese medicine preparation, and compatibility effect each other, can effectively expelling cold and dampness, promoting blood circulation to remove obstruction in the collateral, fixed dizzy, the easypro neck refreshment of suppressing the hyperactive liver, has good effect, advantage that cost is low.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be described in detail.
As follows for the pharmacology analysis situation of component in Chinese medicine preparation of the present invention:
Fang Zhong:
Herba Asari: induce sweat cold expelling, wind-expelling pain-stopping is sensible, warming the lung to resolve fluid-retention, with Ramulus Cinnamomi compatibility, can drive the cold of internal organs;
Rhizoma Et Radix Notopterygii: can the gas of unimpeded governor vessel bladder, has effect of expelling wind and cold pain relieving, and can priming up;
Scorpio: the meridian dredging;
Caulis Spatholobi: the function having relaxing muscles and tendons to promote blood circulation, with Flos Carthami, Radix Angelicae Sinensis compatibility, can effectively treat numb hand and foot, quadriplegia, rheumatic arthralgia;
Herba speranskiae tuberculatae: expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation and stopping pain, joins Caulis Spatholobi, and two medicines share, the liver and the kidney tonifying, promoting blood circulation and stopping pain;
The Radix Angelicae Dahuricae: dispel the wind, dampness, antiinflammatory, detumescence, pain relieving;
Rhizoma Chuanxiong: blood-activating and qi-promoting, wind-expelling pain-stopping, effectively can treat numb limbs and tense tendons.
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, with Rhizoma Et Radix Notopterygii, Ramulus Cinnamomi compatibility, has calmness, analgesia, antibacterial effect;
Semen Strychni: removing obstruction in the collateral to relieve pain, dispersing swelling and dissipating binds;
Olibanum: wind of invigorating blood circulation, muscles and tendons relaxing to alleviate pain, has more significant analgesic activity;
Ramulus Cinnamomi: harmonizing yingfen and weifen with logical sun passages through which vital energy circulates, use same with Flos Carthami,
Radix Puerariae: yang invigorating expelling pathogenic factors from muscles, anxious to separate person's back, matches with Ramulus Cinnamomi,
Flos Carthami: with Radix Angelicae Sinensis, the same use of Rhizoma Chuanxiong, have and nourish blood, invigorate blood circulation, effect of removing blood stasis
All medicines share above, and can effectively improve microcirculation and alleviate local inflammation reaction, reaching congestion must be capable, and numbness hinders the effect that can lead to, and has significant curative effect to treatment cervical spondylosis.
embodiment 1:
The component be used for the treatment of in the Chinese medicine preparation of cervical spondylosis by described: Herba Asari: 10g; Rhizoma Et Radix Notopterygii: 5g; Scorpio: 5g; Caulis Spatholobi: 10g; Herba speranskiae tuberculatae: 8g; The Radix Angelicae Dahuricae: 3g; Rhizoma Chuanxiong: 3g; Radix Angelicae Sinensis: 5g; Semen Strychni: 5g; Olibanum: 3g; Ramulus Cinnamomi: 5g; Radix Puerariae: 3g carries out pulverizing and grinds to form fine powder after mixing, and crosses 80 mesh sieves, is then dropped in mixing and blending machine by the fine powder after sieving and fully mixes, by fine powder every day of every agent Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
 
embodiment 2:
The component be used for the treatment of in the Chinese medicine preparation of cervical spondylosis by described: Herba Asari: 15g; Rhizoma Et Radix Notopterygii: 5g; Scorpio: 5g; Caulis Spatholobi: 10g; Herba speranskiae tuberculatae: 5g; The Radix Angelicae Dahuricae: 5g; Rhizoma Chuanxiong: 5g; Radix Angelicae Sinensis: 5g; Semen Strychni: 5g; Olibanum: 5g; Ramulus Cinnamomi: 5g; Radix Puerariae: 5g carries out pulverizing and grinds to form fine powder after mixing, and crosses 100 mesh sieves, is then dropped in mixing and blending machine by the fine powder after sieving and fully mixes, by fine powder every day of every agent Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
 
embodiment 3:
The component be used for the treatment of in the Chinese medicine preparation of cervical spondylosis by described: Herba Asari: 15g; Rhizoma Et Radix Notopterygii: 8g; Scorpio: 8g; Caulis Spatholobi: 12g; Herba speranskiae tuberculatae: 8g; The Radix Angelicae Dahuricae: 5g; Rhizoma Chuanxiong: 5g; Radix Angelicae Sinensis: 5g; Semen Strychni: 5g; Olibanum: 5g; Ramulus Cinnamomi: 8g; Radix Puerariae: 3g carries out pulverizing and grinds to form fine powder after mixing, and crosses 90 mesh sieves, is then dropped in mixing and blending machine by the fine powder after sieving and fully mixes, by fine powder every day of every agent Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
 
embodiment 4:
The component be used for the treatment of in the Chinese medicine preparation of cervical spondylosis by described: Herba Asari: 15g; Rhizoma Et Radix Notopterygii: 5g; Scorpio: 5g; Caulis Spatholobi: 10g; Herba speranskiae tuberculatae: 5g; The Radix Angelicae Dahuricae: 5g; Rhizoma Chuanxiong: 5g; Radix Angelicae Sinensis: 5g; Semen Strychni: 5g; Olibanum: 5g; Ramulus Cinnamomi: 5g; Radix Puerariae: 5g; Flos Carthami 10g carries out pulverizing and grinds to form fine powder after mixing, and crosses 100 mesh sieves, is then dropped in mixing and blending machine by the fine powder after sieving and fully mixes, by fine powder every day of every agent Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
 
embodiment 5:
The component be used for the treatment of in the Chinese medicine preparation of cervical spondylosis by described: Herba Asari: 125g; Rhizoma Et Radix Notopterygii: 6g; Scorpio: 6g; Caulis Spatholobi: 12g; Herba speranskiae tuberculatae: 6g; The Radix Angelicae Dahuricae: 4g; Rhizoma Chuanxiong: 4g; Radix Angelicae Sinensis: 6g; Semen Strychni: 4g; Olibanum: 4g; Ramulus Cinnamomi: 6g; Radix Puerariae: 4g; Flos Carthami 8g carries out pulverizing and grinds to form fine powder after mixing, and crosses 80 mesh sieves, is then dropped in mixing and blending machine by the fine powder after sieving and fully mixes, by fine powder every day of every agent Chinese medicine preparation at twice, take after mixing it with water in half an hour ante cibum with warm water.
For verifying the clinical effectiveness of invention formulation, carry out clinical experiment.
1, case selection standard:
After the normal experiment inspection of cervical spondylosis, x-ray inspection, electromyogram and CT examination, there is intervertebral disc degradation and insecondary a series of pathological change thereof, as vertebra joint unstability, loosen, Nucleus pulposus or deviate from, bony spur is formed, ligament is plump and the symptom such as the spinal canal stenosis of secondary all as the standard of selection case.
2, diagnostic criteria
Dysphagia, visual disorder, neck heart syndrome, hypertension cervical spondylosis, chest pain, lower extremity paralysis, the symptom such as to damping off.
3, therapeutic scheme
Treatment group 200 example takes the Chinese medicine preparation described in the embodiment of the present invention 3, every day potion, every day twice, it within 10 days, is a course for the treatment of, take 2 courses for the treatment of, matched group 120 example injection Radix Salviae Miltiorrhizae Injection, adds normal saline, intravenous drip, once a day, within 10 days, be a course for the treatment of, instil 2 courses for the treatment of, follow up a case by regular visits to 2 years, through statistical analysis, two groups of case-data there was no significant differences (P<0.05).
4, the course for the treatment of evaluation criteria:
Cure: symptom is eliminated completely, without recurrence;
Effective: transference cure, without recurrence within 1 year;
Effective: symptom obviously alleviates, or partial symptoms disappears, and needs continual cure;
Invalid: symptom does not have any improvement, even there is the trend increased the weight of.
5, therapeutic effect:
Treatment group: cure 78 examples, effective 86 examples, effective 29 examples, invalid 7 examples, total effective rate is 96.5%; Matched group cure 24 example, effective 28 example, effective 36 example, invalid 32 example, total effective rate is 73.3%, treatment group total effective rate apparently higher than matched group, specifically in table 1.
A table 1 liang group therapeutic effect compares
Group Number of cases Cure Effective Effectively Invalid Total effective rate (%)
Treatment group 200 78 86 29 7 96.5
Matched group 120 24 28 36 32 73.3
The present invention is by the medical value of each component in Chinese medicine formula, and compatibility effect each other, can effectively expelling cold and dampness, promoting blood circulation to remove obstruction in the collateral, fixed dizzy, the easypro neck refreshment of suppressing the hyperactive liver, has good effect, advantage that cost is low.
Above detailed description of the invention does not limit the present invention in any form, and every technical scheme obtained in the mode of equivalent replacement or equivalent transformation, all drops in protection scope of the present invention.

Claims (6)

1. be used for the treatment of the Chinese medicine preparation of cervical spondylosis, it is characterized in that, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively:
Herba Asari: 10-15g;
Rhizoma Et Radix Notopterygii: 5-8g;
Scorpio: 5-8g;
Caulis Spatholobi: 10-12g;
Herba speranskiae tuberculatae: 5-8g;
The Radix Angelicae Dahuricae: 3-5g;
Rhizoma Chuanxiong: 3-5g;
Radix Angelicae Sinensis: 5-8g;
Semen Strychni: 3-5g;
Olibanum: 3-5g;
Ramulus Cinnamomi: 5-8g;
Radix Puerariae: 3-5g.
2. the Chinese medicine preparation being used for the treatment of cervical spondylosis according to claim 1, is characterized in that, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively: Herba Asari: 15g; Rhizoma Et Radix Notopterygii: 5g; Scorpio: 5g; Caulis Spatholobi: 10g; Herba speranskiae tuberculatae: 5g; The Radix Angelicae Dahuricae: 5g; Rhizoma Chuanxiong: 5g; Radix Angelicae Sinensis: 5g; Semen Strychni: 5g; Olibanum: 5g; Ramulus Cinnamomi: 5g; Radix Puerariae: 5g.
3. the Chinese medicine preparation being used for the treatment of cervical spondylosis according to claim 1, is characterized in that, also comprise Flos Carthami: 8-10g.
4. the Chinese medicine preparation being used for the treatment of cervical spondylosis according to claim 3, is characterized in that, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively: Herba Asari: 15g; Rhizoma Et Radix Notopterygii: 5g; Scorpio: 5g; Caulis Spatholobi: 10g; Herba speranskiae tuberculatae: 5g; The Radix Angelicae Dahuricae: 5g; Rhizoma Chuanxiong: 5g; Radix Angelicae Sinensis: 5g; Semen Strychni: 5g; Olibanum: 5g; Ramulus Cinnamomi: 5g; Radix Puerariae: 5g; Flos Carthami 10g.
5. the manufacture method being used for the treatment of the Chinese medicine preparation of cervical spondylosis according to claim 1, it is characterized in that, after the described quality proportioning being used for the treatment of each component in the Chinese medicine preparation of cervical spondylosis is mixed, carry out pulverizing and grind to form fine powder, cross 80-100 mesh sieve, then the fine powder after sieving is dropped in mixing and blending machine and fully mix, and for subsequent use according to the metering, distributing, packaging of every agent.
6. the application of Chinese medicine preparation according to claim 5 on preparation treatment cervical spondylosis medicine.
CN201410786120.9A 2014-12-18 2014-12-18 Traditional Chinese medicine preparation for treating cervical spondylosis as well as preparation method and application thereof Pending CN104398576A (en)

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