CN104367953A - Pharmaceutical composition for treating chronic pelvic inflammation - Google Patents
Pharmaceutical composition for treating chronic pelvic inflammation Download PDFInfo
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- CN104367953A CN104367953A CN201410660596.8A CN201410660596A CN104367953A CN 104367953 A CN104367953 A CN 104367953A CN 201410660596 A CN201410660596 A CN 201410660596A CN 104367953 A CN104367953 A CN 104367953A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/902—Sparganiaceae (Bur-reed family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention relates to a pharmaceutical composition for treating chronic pelvic inflammation. The pharmaceutical composition is prepared from the traditional Chinese medicine raw materials in parts by weight: 20-40 parts of honeysuckle stems, 20-40 parts of patrinia, 20-40 parts of salvia miltiorrhiza, 6-10 parts of cortex moutan, 6-10 parts of radix paeoniae rubra, 6-10 parts of rhizoma sparganii, 6-10 parts of curcuma zedoaria, 20-40 parts of suberect spatholobus stems, 20-40 parts of beautiful sweetgum fruits and 10-30 parts of fructus forsythiae. The pharmaceutical composition has the characteristics that blood stasis can be dispersed without blood injury because of the effects of invigorating the blood circulation and replenishing blood, the qi flow in channels is regulated, but is not consumed because of the effects of dispelling melancholy and regulating the qi flow in the channels, and finally, the stasis is dispersed and uterine vessels are circulated; and meanwhile, the pharmaceutical composition can be used for invigorating blood circulation and promoting diuresis, promoting uterine vessel circulation, promoting exudative inflammation absorption and adhered tissue looseness, relieving lesions, effectively relieving pelvic inflammation, salpingitis and hydrops conditions and promoting blood circulation to restore menstrual flow, and has a remarkable effect on treating hypogastric pain, lumbosacral aching pain, pelvic hydrops and infertility caused by fallopian tube obstruction caused by chronic pelvic inflammation.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, specifically a kind of pharmaceutical composition for the treatment of chronic pelvic inflammatory disease.
Background technology
Chronic pelvic inflammatory disease is common gynecological disease, frequently-occurring disease, there is course of disease length, recurrent exerbation, the feature that heals of delay difficulty, have a strong impact on the quality of life of patient, even cause fallopian tube adhesion, block cause infertile, according to clinical experience this mainly blood stasis, yang deficiency cause, add, the work of current women, study, amusement all overload operations, rule of life is more and more unbalance, make endocrine disturbance, the harm of chronic pelvic inflammatory disease is very large, and due to pelvic congestion, the situation that menstruation increases can appear in patient; When ovarian function suffers damage, women there will be menoxenia; When fallopian tube adhesion, obstruction, can cause female acyesis, doctor trained in Western medicine antibiotic therapy short-term is effective, but relapse rate is high, and easily causes endocrine regulation.
Summary of the invention
For the deficiencies in the prior art, the invention provides a kind of pharmaceutical composition for the treatment of chronic pelvic inflammatory disease, do not recur, have no side effect, cure rate is high.
Technical scheme of the present invention is as follows:
Treat a pharmaceutical composition for chronic pelvic inflammatory disease, be made up of the raw material of Chinese medicine of following weight parts proportioning:
Flos Lonicerae rattan 20-40 part, Herba Patriniae 20-40 part, Radix Salviae Miltiorrhizae 20-40 part, Cortex Moutan 6-10 part, Radix Paeoniae Rubra 6-10 part, Rhizoma Sparganii 6-10 part, Rhizoma Curcumae 6-10 part, Caulis Spatholobi 20-40 part, Fructus Liquidambaris 20-40 part, Fructus Forsythiae 10-30 part.
Preferred further, a kind of pharmaceutical composition for the treatment of chronic pelvic inflammatory disease, is made up of the raw material of Chinese medicine of following weight parts proportioning:
30 parts, Flos Lonicerae rattan, Herba Patriniae 30 parts, Radix Salviae Miltiorrhizae 30 parts, Cortex Moutan 9 parts, Radix Paeoniae Rubra 9 parts, Rhizoma Sparganii 9 parts, Rhizoma Curcumae 9 parts, Caulis Spatholobi 30 parts, Fructus Liquidambaris 30 parts, Fructus Forsythiae 20 parts.
Aforementioned pharmaceutical compositions can be made into decoction, pill or tablet, and the present invention is preferably decoction by therapeutic effect, and preparation method is as follows:
(1) important source material of above-mentioned weight portion is put into boccaro tank, add pure water, add water to exceed powder 2-3cm and be advisable, before decocting, soaked by above-mentioned raw material of Chinese medicine, winter soaks 3-4 hour, and summer soaks 1-2 hour, makes it fully moistening;
(2) then boil 8-12 minute with big fire, pour out a medicinal liquid, stay slag, continue to add cold water, add water to exceed powder 2-3cm and be advisable, use moderate heat instead and boil 14-16 minute, pour out secondary medicinal liquid, stay slag; Continue to add cold water, add water to exceed powder 3-5cm and be advisable, use little fire instead and boil 30-35 minute, pour out three medicinal liquids,
(3) medicinal liquid, secondary medicinal liquid, three medicinal liquids are merged, to obtain final product.
The present invention is preferred, and step (2) big fire boils 10 minutes, and moderate heat boils 15 minutes, and little fire boils 35 minutes.
The present invention is preferred, and the obtained remaining medicinal residues gauze of decoction wraps up, and is overlying on lower abdomen.
Usage and dosage: daily once, a menstrual cycle was 1 course for the treatment of to above-mentioned decoction, serve on 6-8 the course for the treatment of.
Technical characterstic of the present invention and advantage:
Chinese medicine is thought, QI-blood circulation is not smooth, stay in silt body, congestion retardance vessels of the uterus, punching is appointed, then can affect germ cell combination, cause infertile, the treatment of Infertility caused by fallopian tube obstruction will catch " silt " word, again in conjunction with body constitution and degree of congestion, with or without adhesion, the situations such as hydrops are treated, the full side's vital energy regualting and blood circulation-promoting of Chinese medicine composition of the present invention, disperse blood stasis and dredge collateral, its feature is blood circulation promoting and enriching, thus blood stasis dispelling and non-blood trouble, resolving depression regulating QI, thus regulate the flow of vital energy and do not consume gas, finally make to be retarded by silt loose, vessels of the uterus must be logical, energy activating blood and promoting diuresis simultaneously, unimpeded vessels of the uterus, promote the absorption of inflammatory seep, the absent-mindedness of adhesion organization, pathological changes is covered, effectively improve pelvic inflammatory disease, salpingitis, hydrops situation, promoting blood flow to regulate menstruation, to the lower abdomen pain that chronic pelvic inflammatory disease causes, lumbosacral aching pain, pelvic hydrops and Infertility caused by fallopian tube obstruction have obvious therapeutic effect.
Detailed description of the invention
Below by specific embodiment, the invention will be further described, but be not limited thereto.
Raw materials usedly in embodiment be convenient source.
Embodiment 1
Treat a pharmaceutical composition for chronic pelvic inflammatory disease, be made up of the raw material of Chinese medicine of following weight parts proportioning:
Flos Lonicerae rattan 30g, Herba Patriniae 30g, Radix Salviae Miltiorrhizae 30g, Cortex Moutan 9g, Radix Paeoniae Rubra 9g, Rhizoma Sparganii 9g, Rhizoma Curcumae 9g, Caulis Spatholobi 30g, Fructus Liquidambaris 30g, Fructus Forsythiae 20g.
It is as follows that aforementioned pharmaceutical compositions makes decoction preparation method:
(1) important source material of above-mentioned weight portion is put into boccaro tank, add pure water, add water to exceed powder 2cm and be advisable, before decocting, above-mentioned raw material of Chinese medicine is soaked, soak 4 hours winter, soak 2 hours summer, make it fully moistening;
(2) then boil 10 minutes with big fire, pour out a medicinal liquid, stay slag, continue to add cold water, add water to exceed powder 2m and be advisable, use moderate heat instead and boil 15 minutes, pour out secondary medicinal liquid, stay slag; Continue to add cold water, add water to exceed powder 4cm and be advisable, use little fire instead and boil 35 minutes, pour out three medicinal liquids,
(3) medicinal liquid, secondary medicinal liquid, three medicinal liquids are merged, to obtain final product.
The present invention is preferred, and step (2) big fire boils 10 minutes, and moderate heat boils 15 minutes, and little fire boils 35 minutes.
The present invention is preferred, and the obtained remaining medicinal residues gauze of decoction wraps up, and is overlying on lower abdomen.
Usage and dosage: daily once, a menstrual cycle was 1 course for the treatment of to above-mentioned decoction, serve on 6-8 the course for the treatment of.
Be described in detail below by the therapeutic effect of clinical data to this medicine:
1. the whole 306 routine patients of physical data are divided into 3 groups at random.Matched group 102 example, 22 ~ 38 years old age, average (30.31 ± 3.53) year, fertility 29 example, infertility 73 example; Treat 1 group of 102 example, 24 ~ 39 years old age, average (31.07 ± 4.00) year, fertility 26 example, infertility 76 example; Treat 2 group of 102 example, 22 ~ 40 years old age, average (30.85 ± 3.87) year, fertility 28 example, infertility 74 example, 3 groups of physical data comparing difference not statistically significants (P > 0.05), have comparability.
2. Therapeutic Method (1) matched group: clean period gives hydrotubation in 3 days, every 1 time on the 2nd, each menstrual cycle totally 3 times, prophylactic postoperative takes antibiotic.Continuous 3 menstrual cycle.(2) treat 1 group: oral treatment by Chinese herbs of the present invention, daily once, a menstrual cycle was 1 course for the treatment of, serve on 6 courses for the treatment of.(3) treat 2 groups: on treatment of control group basis, oral treatment by Chinese herbs of the present invention simultaneously, daily once, a menstrual cycle was 1 course for the treatment of, serve on 8 courses for the treatment of.
3. curative effect determinate standard:
Recovery from illness: uterine pregnancy in a year;
Invalid: not pregnant in 1 year.
4. result
Matched group patient pregnancy rate 30.55%, treats 1 group of patient's pregnancy rate 46.67%, and treating 2 groups of patient's pregnancy rate is 57.83%, and treatment by Chinese herbs patient curative effect is obviously better than matched group.
Claims (5)
1. treat a pharmaceutical composition for chronic pelvic inflammatory disease, be made up of the raw material of Chinese medicine of following weight parts proportioning:
Flos Lonicerae rattan 20-40 part, Herba Patriniae 20-40 part, Radix Salviae Miltiorrhizae 20-40 part, Cortex Moutan 6-10 part, Radix Paeoniae Rubra 6-10 part, Rhizoma Sparganii 6-10 part, Rhizoma Curcumae 6-10 part, Caulis Spatholobi 20-40 part, Fructus Liquidambaris 20-40 part, Fructus Forsythiae 10-30 part.
2. the pharmaceutical composition for the treatment of chronic pelvic inflammatory disease according to claim 1, is characterized in that, is made up of the raw material of Chinese medicine of following weight parts proportioning:
30 parts, Flos Lonicerae rattan, Herba Patriniae 30 parts, Radix Salviae Miltiorrhizae 30 parts, Cortex Moutan 9 parts, Radix Paeoniae Rubra 9 parts, Rhizoma Sparganii 9 parts, Rhizoma Curcumae 9 parts, Caulis Spatholobi 30 parts, Fructus Liquidambaris 30 parts, Fructus Forsythiae 20 parts.
3. the pharmaceutical composition for the treatment of chronic pelvic inflammatory disease according to claim 1, is characterized in that, the pharmaceutical composition of claim 1 makes decoction, and preparation method is as follows:
(1) important source material of above-mentioned weight portion is put into boccaro tank, add pure water, add water to exceed powder 2-3cm and be advisable, before decocting, soaked by above-mentioned raw material of Chinese medicine, winter soaks 3-4 hour, and summer soaks 1-2 hour, makes it fully moistening;
(2) then boil 8-12 minute with big fire, pour out a medicinal liquid, stay slag, continue to add cold water, add water to exceed powder 2-3cm and be advisable, use moderate heat instead and boil 14-16 minute, pour out secondary medicinal liquid, stay slag; Continue to add cold water, add water to exceed powder 3-5cm and be advisable, use little fire instead and boil 30-35 minute, pour out three medicinal liquids,
(3) medicinal liquid, secondary medicinal liquid, three medicinal liquids are merged, to obtain final product.
4. the pharmaceutical composition for the treatment of chronic pelvic inflammatory disease according to claim 1, is characterized in that, step (2) big fire boils 10 minutes, and moderate heat boils 15 minutes, and little fire boils 35 minutes.
5. the pharmaceutical composition for the treatment of chronic pelvic inflammatory disease according to claim 1, is characterized in that, the obtained remaining medicinal residues gauze of decoction wraps up, and is overlying on lower abdomen.
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CN201410660596.8A CN104367953A (en) | 2014-11-18 | 2014-11-18 | Pharmaceutical composition for treating chronic pelvic inflammation |
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CN201410660596.8A CN104367953A (en) | 2014-11-18 | 2014-11-18 | Pharmaceutical composition for treating chronic pelvic inflammation |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105233154A (en) * | 2015-10-22 | 2016-01-13 | 朱坤英 | Detoxifying decoction containing honeysuckle, fructus forsythiae and herba patriniae |
CN105749037A (en) * | 2016-03-30 | 2016-07-13 | 宜都市中医医院 | Traditional Chinese medicine composition for treating chronic pelvic inflammatory disease and preparation method and application thereof |
CN106310204A (en) * | 2016-10-25 | 2017-01-11 | 孙光周 | Traditional Chinese medicine decoction for treating pelvic effusion and salpingemphraxis |
CN112618683A (en) * | 2021-01-14 | 2021-04-09 | 佛山市欣康迈科技有限公司 | Medicine for treating fallopian tube obstruction and preparation method thereof |
-
2014
- 2014-11-18 CN CN201410660596.8A patent/CN104367953A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105233154A (en) * | 2015-10-22 | 2016-01-13 | 朱坤英 | Detoxifying decoction containing honeysuckle, fructus forsythiae and herba patriniae |
CN105749037A (en) * | 2016-03-30 | 2016-07-13 | 宜都市中医医院 | Traditional Chinese medicine composition for treating chronic pelvic inflammatory disease and preparation method and application thereof |
CN106310204A (en) * | 2016-10-25 | 2017-01-11 | 孙光周 | Traditional Chinese medicine decoction for treating pelvic effusion and salpingemphraxis |
CN112618683A (en) * | 2021-01-14 | 2021-04-09 | 佛山市欣康迈科技有限公司 | Medicine for treating fallopian tube obstruction and preparation method thereof |
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