CN104352699A - Traditional Chinese medicine ointment for treating burns and bedsore and preparation method thereof - Google Patents

Traditional Chinese medicine ointment for treating burns and bedsore and preparation method thereof Download PDF

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Publication number
CN104352699A
CN104352699A CN201410683879.4A CN201410683879A CN104352699A CN 104352699 A CN104352699 A CN 104352699A CN 201410683879 A CN201410683879 A CN 201410683879A CN 104352699 A CN104352699 A CN 104352699A
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parts
radix
traditional chinese
scald
burn
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张井强
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/35Extraction with lipophilic solvents, e.g. Hexane or petrol ether
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention discloses traditional Chinese medicine ointment for treating burns and bedsore. The ointment is prepared from the following medicinal raw materials in parts by weight: 20 parts of sanguisorba officinalis, 20 parts of dragon blood, 20 parts of scutellaria baicalensis, 20 parts of coptis chinensis, 20 parts of cortex phellodendri, 20 parts of human hair, 20 parts of poppy shell, 30 parts of lithospermum, 20 parts of gypsum rubrum, 20 parts of gypsum, 40 parts of mungbean, 20 parts of borneol, 1000 parts of sesame oil and 80 parts of beewax. By adopting the ointment, epithelial tissues can quickly grow, infection can be effectively controlled, and the color of the recovered skin has small difference from normal skin color.

Description

The traditional Chinese herb medicine for the treatment of burn and scald, decubital ulcer and manufacture method
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind ofly treat burn and scald, the traditional Chinese herb medicine of decubital ulcer and its preparation method.
Background technology
Current treatment ointment for burns and scalds is that what have needs dermatoplastic treatment to dark II degree, III degree burn and scald, and the ointment for the treatment of decubital ulcer, leaves cicatrix after treatment, and the speed of recovery is slow, does not reach promising result.
Summary of the invention
The object of the invention is the deficiency existed for prior art, provide and a kind ofly treat burn and scald, the traditional Chinese herb medicine of decubital ulcer and its preparation method.
The object of the invention is to be realized by following technological means:
The traditional Chinese herb medicine for the treatment of burn and scald, decubital ulcer, calculating by weight crude drug material is: Radix Sanguisorbae 20 parts, Sanguis Draxonis 20 parts, Radix Scutellariae 20 parts, Rhizoma Coptidis 20 parts, Cortex Phellodendri 20 parts, hemopoietic more than 20 parts, Pericarpium Papaveris 20 parts, Radix Arnebiae (Radix Lithospermi) 30 parts, Mirabilitum crystallina 20 parts, 20 parts, Gypsum Fibrosum, 40 parts, Semen phaseoli radiati, Borneolum Syntheticum 20 parts, 1000 parts, Oleum Sesami, 80 parts, Cera Flava.
The preparation method of the traditional Chinese herb medicine for the treatment of burn and scald, decubital ulcer, get that Radix Scutellariae, Rhizoma Coptidis, Cortex Phellodendri, hemopoietic are remaining, Radix Sanguisorbae, Pericarpium Papaveris, Radix Arnebiae (Radix Lithospermi) put in Oleum Sesami and soak 3 days, explode withered filtration with slow fire, Oleum Sesami is continued heating, Cera Flava is melted, continuous stirring, endures to dark-brown for spending, when being chilled to 60o ~ 80oC, add Mirabilitum crystallina powder, Gypsum Fibrosum powder, Semen phaseoli radiati powder, when being cooled to 50o ~ 60oC, add Borneolum Syntheticum, Sanguis Draxonis also constantly stirs, until become ointment shape.
Fang Zhong: Radix Scutellariae, Rhizoma Coptidis, Cortex Phellodendri, heat clearing and damp drying.Separate scar fire-toxin, pyretic toxicity carbuncle knot, tissue regeneration promoting meat, corrosion removal, receipts water wet, reducing swelling and alleviating pain; Semen phaseoli radiati: Xie Zhure, QI invigorating, control burn and scald burn; Radix Arnebiae (Radix Lithospermi): bitter cold, relieving heat toxin, go to dislike rotten; Pericarpium Papaveris: astringent therapy, relieve the pain pain; More than hemopoietic: to put on flesh the congestion that disappears with soft extracts; Mirabilitum crystallina: pungent cold nontoxic, control to scald to burn and burn; Gypsum Fibrosum: pungent, sweet, Great Cold, control skin infection fester do not conform to, scald fiery rotten skin ulcer; Borneolum Syntheticum: pungent, bitter, be slightly cold, removing the necrotic tissue and promoting granulation, clearing away heat to alleviate pain; Sanguis Draxonis: sweet, salty, flat, removing the necrotic tissue and promoting granulation, scattered silt pain relieving; Cera Flava: sweet, tepor, the red pain of burn and scald Chuan, inflammation, poison corruption pus, with this pull out pyretic toxicity, relieve the pain pain, sore mouth; Oleum Sesami and Oleum sesami: sweet, be slightly cold, granulation promoting is put on flesh, pain relieving, the pain that disappears are swollen, mend rhagades of the skin; All medicines share, and amount to live silt, anti-inflammatory and antalgic, granulation promoting, promotion wound repair.
Compared with prior art the present invention has following obvious advantage: can bear epithelial tissue fast, effective infection control, after rehabilitation color and luster and normal skin tone difference little.
Detailed description of the invention
The traditional Chinese herb medicine for the treatment of burn and scald, decubital ulcer, calculating by weight crude drug material is: Radix Sanguisorbae 20 parts, Sanguis Draxonis 20 parts, Radix Scutellariae 20 parts, Rhizoma Coptidis 20 parts, Cortex Phellodendri 20 parts, hemopoietic more than 20 parts, Pericarpium Papaveris 20 parts, Radix Arnebiae (Radix Lithospermi) 30 parts, Mirabilitum crystallina 20 parts, 20 parts, Gypsum Fibrosum, 40 parts, Semen phaseoli radiati, Borneolum Syntheticum 20 parts, 1000 parts, Oleum Sesami, 80 parts, Cera Flava.
The preparation method of the traditional Chinese herb medicine for the treatment of burn and scald, decubital ulcer, get that Radix Scutellariae, Rhizoma Coptidis, Cortex Phellodendri, hemopoietic are remaining, Radix Sanguisorbae, Pericarpium Papaveris, Radix Arnebiae (Radix Lithospermi) put in Oleum Sesami and soak 3 days, explode withered filtration with slow fire, Oleum Sesami is continued heating, Cera Flava is melted, continuous stirring, endures to dark-brown, when being chilled to 60o ~ 80oC, add Mirabilitum crystallina powder, Gypsum Fibrosum powder, Semen phaseoli radiati powder, when being cooled to 50o ~ 60oC, add Borneolum Syntheticum, Sanguis Draxonis also constantly stirs, until become ointment shape.
Directly be coated on gauze with ointment, external application affected part, the next day, changes dressings once.
Clinical treatment criterion standard and result:
Name of disease Number Recovery from illness Effective Invalid Total effective rate
Burn and scald 362 340 22 0 100%
Decubital ulcer 28 20 8 0 100%
Recovery from illness standard: wound surface uniform fold one deck epithelial tissue, preventing from scar, but color and luster and normal skin tone difference to some extent.Effective standard: the granulation that wound surface grows, above normal skin, forms cicatrix.Null criterion: can not infection control after medication, ulcer surface does not reduce, and this group case is minimum changes dressings 2 times, and maximum 30 times, therapeutic outcome is in Table.
Burn and scald clinical treatment 362 example, the longest 60 days, the shortest 3 days, total effective rate 100%, cure rate 96%.Decubital ulcer clinical treatment 28 example, the longest 60 days, the shortest 3 days, total effective rate 100%, cure rate 72%.
Medical record is illustrated:
1, Lu, man, 51 years old, electrician.In work on June 2nd, 2014, the right hand is burnt by high-tension electricity accidentally, hands is to ancon, interior outside corium deep layer, part skin accessory structure, third-degree burn, belong to deepⅱdegreeburn, account for body surface area 5.5%, outer painting burn and scald, bedsore ointment, the next day, changes dressings once, January fully recovers, without cicatrix, color and luster and colour of skin difference to some extent, meet each other after half a year, the colour of skin is as usual.
2, Wang, man, 38 years old.Drunk rear gas range igniting smoking on February 20th, 2012, Fire explosion revealed by gas pipe.Affiliated Hospital of urban district Jining City delivered to by ambulance.Within ten days, went to a doctor afterwards.Meeting portion, both hands burn of back, belong to the degree of depth and scald, body surface area 8%. external medicine cream, changes dressings 1 time every other day, recovery from illness in 25 days, without cicatrix, color and luster and colour of skin difference to some extent.
3, high certain, 1 years old half.On October 8th, 2013, its mother was put one bowl of hot medicated porridge on dining table, accidentally by high certain grab askew, before scalding machine lower lip, foreneck, front, account for body surface area 6%.Corium deep layer, part skin belongs to structure and scalds, and belongs to dark II degree of scald, and the recovery from illness in 20 days of external medicine cream, without cicatrix, color and luster and skin difference to some extent.
4, Guo, 53 years old.Occupation ironsmith, burns red iron block on February 29th, 2012 and loses instep, and connect to scald to add and pound, after necrotic tissue cleaning, visible sclerotin belongs to deep burn, is coated with outward with ointment, fully recovers after 30 days, without cicatrix, and color and luster 3 and colour of skin difference to some extent.
5, road, 90 years old.The left lower limb of traumatic injury on February 6 in 2013, after the conservative treatment March of lying low, finds that tail rumpbone festers to waist, deeply reaches surface of bone, after external application burn and scald, band bed sore ointment 7 times, the tissue that rots is removed, and green meat blastogenesis goes out, adhere to treatment recovery from illness in 60 days, skin recovers normal, color and luster and normal skin difference to some extent.
Above data can be found out, the treatment of the present invention to burn and scald, decubital ulcer has significant curative effect.
The above; be only a part of detailed description of the invention of the present invention, protection scope of the present invention is not limited thereto, and is anyly familiar with those skilled in the art in the technical scope that the present invention discloses; the change that can expect easily or replacement, all should be encompassed within protection scope of the present invention.

Claims (2)

1. treat the traditional Chinese herb medicine of burn and scald, decubital ulcer, it is characterized in that: calculating by weight crude drug material is: Radix Sanguisorbae 20 parts, Sanguis Draxonis 20 parts, Radix Scutellariae 20 parts, Rhizoma Coptidis 20 parts, Cortex Phellodendri 20 parts, hemopoietic more than 20 parts, Pericarpium Papaveris 20 parts, Radix Arnebiae (Radix Lithospermi) 30 parts, Mirabilitum crystallina 20 parts, 20 parts, Gypsum Fibrosum, 40 parts, Semen phaseoli radiati, Borneolum Syntheticum 20 parts, 1000 parts, Oleum Sesami, 80 parts, Cera Flava.
2. the method for the traditional Chinese herb medicine of preparation treatment burn and scald according to claim 1, decubital ulcer, it is characterized in that: get that Radix Scutellariae, Rhizoma Coptidis, Cortex Phellodendri, hemopoietic are remaining, Radix Sanguisorbae, Pericarpium Papaveris, Radix Arnebiae (Radix Lithospermi) put in Oleum Sesami and soak 3 days, explode withered filtration with slow fire, Oleum Sesami is continued heating, Cera Flava is melted, continuous stirring, endures to dark-brown, when being chilled to 60o ~ 80oC, add Mirabilitum crystallina powder, Gypsum Fibrosum powder, Semen phaseoli radiati powder, when being cooled to 50o ~ 60oC, add Borneolum Syntheticum, Sanguis Draxonis also constantly stirs, until become ointment shape.
CN201410683879.4A 2014-11-25 2014-11-25 Traditional Chinese medicine ointment for treating burns and bedsore and preparation method thereof Pending CN104352699A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104740067A (en) * 2015-04-07 2015-07-01 万小耀 External medicinal composition for treating scalds, external ointment for treating scalds and preparation method thereof
CN104740106A (en) * 2015-04-07 2015-07-01 万小耀 External-use pharmaceutical composition for treating scalds, external-use medicinal oil for treating scalds and preparation method for external-use medicinal oil

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1055297A (en) * 1991-03-28 1991-10-16 许聿祥 A kind of autofrettage of skin-moistening burn and scald medicine
CN102058781A (en) * 2010-12-24 2011-05-18 林栋� Traditional Chinese medicinal film agent for treating burns and scalds
CN102205024A (en) * 2011-05-27 2011-10-05 沈大友 Ointment for treating burns and preparation method thereof
CN102579820A (en) * 2011-01-07 2012-07-18 韦军来 Ointment for treating burns and scalds and preparation method of ointment

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Publication number Priority date Publication date Assignee Title
CN1055297A (en) * 1991-03-28 1991-10-16 许聿祥 A kind of autofrettage of skin-moistening burn and scald medicine
CN102058781A (en) * 2010-12-24 2011-05-18 林栋� Traditional Chinese medicinal film agent for treating burns and scalds
CN102579820A (en) * 2011-01-07 2012-07-18 韦军来 Ointment for treating burns and scalds and preparation method of ointment
CN102205024A (en) * 2011-05-27 2011-10-05 沈大友 Ointment for treating burns and preparation method thereof

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吴倩: ""湿润烧伤膏在临床中的应用"", 《中国民族民间医药》 *
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104740067A (en) * 2015-04-07 2015-07-01 万小耀 External medicinal composition for treating scalds, external ointment for treating scalds and preparation method thereof
CN104740106A (en) * 2015-04-07 2015-07-01 万小耀 External-use pharmaceutical composition for treating scalds, external-use medicinal oil for treating scalds and preparation method for external-use medicinal oil

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Application publication date: 20150218