CN104345647A - Automatic control system used for refrigeration of medical and biological medicines - Google Patents
Automatic control system used for refrigeration of medical and biological medicines Download PDFInfo
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- CN104345647A CN104345647A CN201310336710.7A CN201310336710A CN104345647A CN 104345647 A CN104345647 A CN 104345647A CN 201310336710 A CN201310336710 A CN 201310336710A CN 104345647 A CN104345647 A CN 104345647A
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- storage disk
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- refrigeration
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- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B19/00—Programme-control systems
- G05B19/02—Programme-control systems electric
- G05B19/04—Programme control other than numerical control, i.e. in sequence controllers or logic controllers
- G05B19/042—Programme control other than numerical control, i.e. in sequence controllers or logic controllers using digital processors
- G05B19/0423—Input/output
Abstract
The invention relates to the technical field of automatic control and particularly relates to an automatic control system used for refrigeration of medical and biological medicines. The system includes a refrigeration chamber, an automatic access gate, a sample pool, a sample automatic conveyance mechanism, a barcode scanner, a programmable controller and an upper computer. The refrigeration chamber is an enclosed body and the automatic access gate device is arranged between an external environment and the refrigeration chamber. The sample pool and the sample automatic conveyance mechanism are both arranged in the refrigeration chamber. The barcode scanner is installed on a sample conveyance path. Sensors and electrical parts in the automatic access gate, the sample pool, and the sample automatic conveyance mechanism are all connected with the programmable controller. The barcode scanner and the programmable controller are both connected with the upper computer. The system realizes automatic access of samples and data intelligent management and has the characteristics of being simple in structure and large in sample storage capacity and through arrangement of two gates, internal and external environments are effectively isolated so that fluctuation of the refrigeration environment caused by door opening is prevented and the stability of the refrigeration environment and sample quality and safety are ensured and remote monitoring is easy to realize.
Description
Technical field
The present invention relates to automatic control technology field, in particular for the automatic control system of this refrigeration of medicine bioengineering medicine.
Background technology
Sample size in the laboratory of biomedicine field is many, batch more than, most of research institution does not have special sample management system, the written management of management and long-term implementation of sample, cause that sample utilization factor is low, information delay, cannot the problem such as real-time follow-up achievement in research.Add that flow of personnel is large, achievement in research can not be shared, and experimental work handover procedure is loaded down with trivial details, does not have unified standard, bring larger difficulty to the preservation of sample, use and management work to reagent and the handing-over of compound equal samples.
Along with the improvement of HIGH POWER PROTON ACCELERATOR, biology laboratory sample size increases gradually, simply unordered sample managing pattern in the past can not adapt to current need of work, the management in laboratory needs to be improved further, how more efficiently, easily management misconduct room sample be the key subjects being badly in need of at present solving, especially in laboratory, the scientific management of biological products and chemicals just seems especially important for the fast development in whole laboratory and orderly function.At present in the urgent need to a kind of efficiently, easily sample access system meet in Development of Laboratories process the needs that sample accurately manages.
At present, the bottleneck of restriction China biological medicine research is instrument and equipment, and relevant high-end instrument and equipment is import mostly, and can not give full play to their function, the more important thing is and can't buy state-of-the-art instrument and equipment.Domestic many research institutions do not have special sample management system, the written management of management and long-term implementation of sample, cause that sample utilization factor is low, information delay, cannot the problem such as real-time follow-up achievement in research.Sample Storehouse both domestic and external, from preservation container, the main traditional refrigerator (cabinet) adopted is preserved, and part have employed liquid nitrogen container and preserves, and also has very fraction pilot mechanical arm automated sample storehouse.From data management, major part also rests on the simple data storehouse epoch, only has part Sample Storehouse to develop private database, and has done interface with large database.
Biological medicine sample needs to store under freezing or cold storage environment, also can take out from freezing or cold storage environment simultaneously, no matter be that situation, capital needs the room door opening cold storage environment (as refrigerator, refrigerator-freezer), sometimes opening is frequently, this just causes the convection current of inner air and outer air, and cold storage environment (temperature, humidity etc.) certainly will be caused like this to change, and affects the stable of storage condition.Research shows, pharmaceutical preparation, medicine performance, biological specimen (blood plasma, serum, whole blood, lymph, saliva, various tissue, hair, urine, bile, tear, spinal fluid, sweat, milk, amniotic fluid etc.), vaccine store and the storage condition of vegetables meat all has a significant impact its performance, quality.
Existing refrigerating equipment (as refrigerator, refrigerator-freezer) is all deposit or pulling items by arranging a larger room door.Article are when storing and take out, capital needs the room door opening cold storage environment (as refrigerator, refrigerator-freezer), sometimes opening is frequently, this just causes the convection current of inner air and outer air, cold storage environment (temperature, humidity etc.) certainly will be caused like this to change, affect the stable of storage condition, particularly harsh article are required to storage condition, small storage condition change all can affect its quality, also can make freezing or refrigerating equipment frequent starting simultaneously, increase power consumption, improve storage cost.
The quantity of sample is on the increase, and need the quantity of information of record also increasing, in the face of so many information, traditional way to manage seems awkward.At present, market there is no the product that can meet this demand, and this product is to the storage of sample, management and particular importance, in order to improve the storage quality of sample and researchist be freed from loaded down with trivial details sample management, a kind of automatic sampling, the metering that under cold storage environment, sample can be completed according to research process requirements must be researched and developed, novel sample automatic access and the intelligent management system of registration management can be carried out again sample service condition.
No matter domestic or external, the unit of research data base is many, provides the enterprise of freezing equipment also very well-known, but, the successful case that sample technique of refrigeration, sample automatic access technology combine with sample data library management is not also had.
Summary of the invention
The object of the invention is the automatic control system being provided for this refrigeration of medicine bioengineering medicine in order to overcome above-mentioned technical disadvantages.
The technical scheme that technical solution problem of the present invention adopts is: for the automatic control system of this refrigeration of medicine bioengineering medicine, comprise reefer, automatic access sluice gate, Sample Storehouse, sample automatic delivering mechanism, barcode scanner, Programmable Logic Controller (PLC) and host computer; Reefer is an obturator, and automatic access sluice gate is arranged on reefer sidewall, and Sample Storehouse and sample automatic delivering mechanism are all arranged in reefer; Barcode scanner is arranged on the path that sample is conveyed through; Sensor in automatic access sluice gate, Sample Storehouse and sample automatic delivering mechanism is all connected with Programmable Logic Controller with execution unit; Barcode scanner is all connected with host computer with Programmable Logic Controller;
Described automatic access sluice gate, it is the transition passage being used for accessing sample that reefer and space outerpace contact, flood tide gate is provided with between this transition passage and external environment condition, and be provided with interior automatically-controlled door between cold storage environment, a zone of transition is provided with between flood tide gate and interior automatically-controlled door, be provided with in zone of transition and the gas access of reefer ft connection and exhausr port, the cryogenic gas entrance be communicated with cooling compartment and protective gas entrance, these mouths are all provided with valve; Pressure transducer and Temperature Humidity Sensor is provided with in zone of transition; Arrange the sample tray of a movement in the inner side that interior automatically-controlled door is in reefer, the inner side of sample tray is provided with a delivery device;
Described Sample Storehouse, comprises central shaft, sample storage disk and disk driving mechanism, central shaft bottom is arranged on a pedestal, each sample storage disk is installed in parallel on central shaft, sealing gasket is provided with between adjacent sample storage disk, sample storage disk is distributed with sample nest and sample delivery channel, corresponding to all sample storage disks, a set of disk driving mechanism is at least set, disk driving mechanism is arranged on one and is fixed on the support of pedestal, sample nest adopts many form of annular rings to be arranged on sample storage disk, sample nest is circular distribution, number of rings is at least two rings, all annulus are concentric, each annulus is at least arranged a sample delivery channel,
Described sample automatic delivering mechanism, comprise lifting apparatus and absorption conveying device, lifting apparatus is arranged on the below of bottom sample storage disk, comprise and lift air jet pipe and gas puff Z-pinch valve, arrange one corresponding to each sample delivery channel on bottom sample storage disk and lift air jet pipe, lift on air jet pipe and be connected with gas puff Z-pinch valve, lift air jet pipe and be connected with source of the gas; Absorption conveying device is arranged on the top of most top layer sample storage disk, comprise combination air-breathing seat, air intake duct, suction control valve, delivery pipe, pipage control valve and vacuum storehouse, each sample delivery channel corresponded on most top layer sample storage disk arranges an air intake duct, air intake duct is connected with suction control valve, each air intake duct is all connected with vacuum storehouse, delivery pipe one end is connected with vacuum storehouse, and one end is connected to sample tray, delivery pipe is connected with pipage control valve.
Described disk driving mechanism comprises servomotor and gear train, and servomotor is connected with the input end of gear train, and the output terminal of gear train connects on a rotary disc.Gear train can adopt the various mechanism that can make disk rotational such as V belt translation, toothed belt transmission, gear drive, rack pinion.
The beneficial effect that the present invention has is: the present invention changes the opening/shutting mode of traditional cold storage environment, can realize the automatic access of sample, has the advantages that structure is simple, sample storing capacity is large; There is temperature, humidity coupling controlling functions, there is inert gas protection device, reduce the fluctuation of cold storage environment as far as possible, avoid the change of cold storage environment, ensure that the stable of cold storage environment, ensured sample qualities and safety; The storage of sample and sample data information association can be got up, allow researchist free from loaded down with trivial details sample management.
Accompanying drawing explanation
Accompanying drawing 1 is structural representation of the present invention.
Accompanying drawing 2 is the structural representation of automatic access sluice gate of the present invention.
Accompanying drawing 3 is that the structure of Sample Storehouse of the present invention and sample automatic delivering mechanism is bowed diagram.
Accompanying drawing 4 is the structural front view of Sample Storehouse of the present invention and sample automatic delivering mechanism.
Accompanying drawing 5 is that of the present invention bottle is stored in process flow diagram.
Embodiment
Below in conjunction with accompanying drawing 1 ~ accompanying drawing, 5 couples of the present invention are described below.
As shown in Fig. 1 ~ 5,1, reefer, 2, automatic access sluice gate, 3, Sample Storehouse, 4, sample automatic delivering mechanism, 5, barcode scanner, 6, Programmable Logic Controller, 7, host computer; 201, flood tide gate, 202, interior automatically-controlled door, 203, zone of transition, 204, sample tray, 205, cooling compartment, 206, reefer is outside, and 2031, outer gas inlets, 2032, protective gas entrance, 2033, cryogenic gas entrance, 2034, exhausr port, 2035, temperature and humidity controller, 2036, pressure controller; 301, sample storage disk, 302, sample nest, 303, sample delivery channel, 304, sealing gasket, 305, specimen bottle, 306, pedestal, 307, central shaft; 401, air-breathing seat is combined, 402, suction control valve, 403, air intake duct, 404, vacuum pump, 405, vacuum control valve, 406, vacuum storehouse, 407, lift air jet pipe, 408, gas puff Z-pinch valve, 409, air compressor, 410, delivery pipe, 411, pipage control valve.
The present invention, comprises reefer 1, automatic access sluice gate 2, Sample Storehouse 3, sample automatic delivering mechanism 4, barcode scanner 5 and Programmable Logic Controller 6 and host computer 7.Reefer 1 is an obturator, substantially the same with the structure of existing refrigerator-freezer, and just surrounding is sealing, only sidewall is provided with an automatic access sluice gate 2., and automatic access sluice gate 2 is set at this.Sample Storehouse 3 and sample automatic delivering mechanism 4 are all arranged in reefer 1.
Below the structure of automatic access sluice gate 2, Sample Storehouse 3 and sample automatic delivering mechanism 4 is elaborated.
The structure of automatic access sluice gate 2 as shown in Figure 2, is a transition passage being arranged on reefer 1 sidewall, is between external environment condition and reefer environment.Be provided with flood tide gate 201 between this transition passage and reefer outside 206, and between cooling compartment 205, be provided with interior automatically-controlled door 202, between flood tide gate 201 and interior automatically-controlled door 202, be provided with a zone of transition 203.The automatically-controlled door that interior automatically-controlled door 202 can adopt light-operated automatically-controlled door or alternate manner to control.Flood tide gate 201 can adopt manually operated door, also can adopt automatically-controlled door.The exhausr port 2034 being communicated with cryogenic gas entrance 2033 with cooling compartment 205 and being communicated with reefer outside 206 is set in the side of zone of transition 203; opposite side arranges the outer gas inlets 2031 be communicated with reefer outside 206 and the protective gas entrance 2032 be communicated with external protective gas source; these mouths are all provided with valve, to open or close.Outer gas inlets 2031 is communicated with external environment condition, and cryogenic gas entrance 2033 is communicated with cold storage environment, and protective gas entrance 2032 is communicated with external protective gas source, and protective gas is all kinds of gases being applicable to article protection, as various inert gas.In zone of transition 203, temperature and humidity controller 2035 and pressure controller 2036 are installed, so that regulation and control zone of transition 203 environment.A transportable sample tray 204 is set inside interior automatically-controlled door 202, the inner side of sample tray 204 is provided with a delivery device (not drawing in Fig. 2), this delivery device can be cylinder, hydraulic cylinder, electric pushrod or a mechanical arm, also can be the specimen bottle on sample tray 204 can be made to push zone of transition 203 or take out other mechanism of zone of transition 203.Sample tray enters zone of transition from cold storage environment room be advanced by delivery device, and delivery device action and interior automatically-controlled door action are synchronously carried out, and are controlled, enter zone of transition from external environment, manually advance by PLC.
The course of work of automatic access sluice gate 2 is as follows:
One, sample is taken out from cooling compartment 205
1, first according to the preservation feature will taking out sample; a transitional environment is built in zone of transition 203; pass into extraneous gas to improve temperature in zone of transition 203 or humidity by outer gas inlets 2031, pass into protective gas by protective gas entrance 2032.By the humiture in temperature and humidity controller 2035 detection and control zone of transition 203, according to sample, requirement is changed to humiture, determine unlatching or the closedown of outer gas inlets 2031.Also according to its requirement, the pressure in zone of transition 203 to be detected by pressure controller 2036, Control protection gas intake to the sample that some have particular/special requirement.
2, sample automatic delivering mechanism 4 is placed on the sample tray 204 inside interior automatically-controlled door 202 automatically stored in the specimen bottle 305 (see Fig. 4) in Sample Storehouse 3.
3, when needs are transported to zone of transition 203 by reefer through interior automatically-controlled door 202 sample tray 204, interior automatically-controlled door 202 is opened automatically according to PLC instruction, by the delivery device in cold storage environment region, the specimen bottle 405 on sample tray 204 is delivered to zone of transition 203, delivery device is return.
4, sample stays for some time in zone of transition 203, and adapt to external environment condition gradually, to avoid the sharply change due to environment, sample is impacted, when specimen bottle 305 the humiture of zone of transition 203, pressure and retention time meet sample transfer require time, open flood tide gate 201 and specimen bottle 305 taken away.
Two, by outside 206 stored samples of reefer
1, be the same with the 1st step of taking out sample from cooling compartment 205.
2, open flood tide gate 201 and sample tray 204 is put into zone of transition 3, sample stays for some time in zone of transition 203, sample is first cooled gradually, adapt to cold storage environment gradually, to avoid the sharply change due to environment, sample is impacted, then interior automatically-controlled door 202 is according to PLC instruction unpack (starting timing while opening flood tide gate 201), and delivery device stretches out to be brought into sample tray 204, then passes through sample automatic delivering mechanism 4 specimen bottle 305 stored in Sample Storehouse 3.
As shown in Figure 3 and Figure 4, the structure of Sample Storehouse 3 comprises central shaft 307, sample storage disk 301 and disk driving mechanism, and central shaft 307 bottom is arranged on pedestal 306.Central shaft 307 is provided with plural sample storage disk 301, sample storage disk 301 is arranged on central shaft 307 up and down abreast by bearing, is provided with sealing gasket 304 between adjacent sample storage disk 301.Sample storage disk 301 is distributed with sample nest 302 and sample delivery channel 303 (see Fig. 1).Sample nest 302 on sample storage disk 301, sample nest 302 adopts many loop types to be arranged on sample storage disk 301, and sample nest 302 is in circular distribution, and number of rings is at least two rings, all annulus are with one heart, and each circle at least arranges a sample delivery channel 303.Two sample delivery channel (namely the angle of two sample delivery channel equals 180 degree) can be symmetrical arranged on each annulus, the center of the sample delivery channel on all annulus is in one diametrically, like this when accessing sample, driving mechanism only needs to allow disc rotary≤90 degree just can find suitable sample delivery channel.Corresponding to all sample storage disks, a set of disk driving mechanism (disk driving mechanism not shown in FIG.) is at least set, can be that each disk arranges a set of driving mechanism, also can be that several disk or all disks share a set of driving mechanism, if several disk or all disks share a set of driving mechanism, this driving mechanism can be slided up and down by elevating mechanisms such as screw pairs, just this driving mechanism is moved to this disk place when needing to rotate some disks, be connected with this disk, certainly this driving mechanism must be can the gear train of movement, as gear drive.Each cover disk driving mechanism is installed on a support, and this support is fixed on pedestal 306.Disk driving mechanism comprises servomotor and gear train, servomotor is arranged on described support, gear train can adopt V belt translation, and (driving wheel is arranged on servomotor, engaged wheel made by sample storage disk 301), gear drive (driving gear is arranged on servomotor, and follower gear made by sample storage disk 301), the various mechanism that sample storage disk 301 can be made to rotate such as rack pinion.
Sample delivery channel 303 is through holes, its aperture is slightly larger than the external diameter of sample nest 302, this is conducive to specimen bottle and enters sample delivery channel 303 smoothly from sample nest, simultaneously, annular flow can also be formed outside specimen bottle, specimen bottle just surrounds at air-flow and passes through sample delivery channel under clustering round, thus reduces the frictional resistance with sidewall; The aperture of sample nest is greater than specimen bottle external diameter, has the aperture being less than specimen bottle external diameter bottom sample nest, specimen bottle can be placed in sample nest like this, and can not fall from sample nest, and its power of still lifting implements gas passage simultaneously.
As shown in Figure 3 and Figure 4, the structure of sample automatic delivering mechanism, comprises lifting apparatus and absorption conveying device.Lifting apparatus is arranged on the below of bottom sample storage disk, comprise and lift air jet pipe 407 and gas puff Z-pinch valve 408, arrange one corresponding to each sample delivery channel 303 on sample storage disk 301 and lift air jet pipe 407 (only drawing in Fig. 2), lift on air jet pipe 407 and be connected with gas puff Z-pinch valve 408, gas puff Z-pinch valve 408 adopts autocontrol valve (solenoid valve etc.), lift air jet pipe 407 to be connected with source of the gas, source of the gas adopts air compressor 409.Lift air jet pipe 407 can be fixed on the support of installation disk driving mechanism.By opening gas puff Z-pinch valve 408, making pressure gas enter sample delivery channel 303 and sample nest 302 by lifting air jet pipe 407, the specimen bottle 305 in sample nest 302 is upwards lifted.Absorption conveying device is arranged on the top of the superiors' sample storage disk, comprise air intake duct 403, suction control valve 402, delivery pipe 410, delivery pipe operation valve 411 and vacuum storehouse 406, an air intake duct 403 is set corresponding to each sample delivery channel 303 on sample storage disk 301, air intake duct 403 is connected with suction control valve 402.In order to being convenient to install and operation, also each air intake duct 403 can being connected on a combination air-breathing seat 401, combining air-breathing seat 401 and be provided with the air entry corresponding with each sample delivery channel 303.Each air intake duct 403 or combination air-breathing seat 401 can be fixed on the support of installation disk driving mechanism.Each air intake duct 403 is all connected with vacuum storehouse 406.Delivery pipe 410 one end is connected with vacuum storehouse 406, delivery pipe 410 is connected with delivery pipe operation valve 411, and one end is connected to sample tray 204.Suction control valve 402 and delivery pipe operation valve 411 adopt autocontrol valve (solenoid valve etc.).Vacuum storehouse 406 is connected with vacuum pump 404, connecting line is provided with vacuum control valve 405, on vacuum storehouse 406, vacuum meter can be installed, make to produce negative pressure in vacuum storehouse 406 by vacuum pump 404, open suction control valve 402, air intake duct 403 pairs of sample delivery channel 303 and sample nest 302 aspirate, by specimen bottle 305 sucking-off in sample nest 302.Lifting the lifting with under the swabbing action of air intake duct 403 of air jet pipe 407, specimen bottle 305 is removed sample storage disk 301, is transported on the sample tray 204 in automatic access sluice gate 2 through delivery pipe 410.If specimen bottle 305 to be put into the sample nest of sample storage disk 301, also corresponding step is taked, sample nest is allowed to align with sample delivery channel, by the specimen bottle 305 inhale pipe 403 that delivery pipe 410 will be placed in automatic access sluice gate 2 on sample tray 204, drop in the sample nest of specifying through air intake duct 403.For ensureing that specimen bottle steadily falls into sample nest, prevent specimen bottle freely falling body, specimen bottle is lifted by lifting air jet pipe 407, specimen bottle is allowed to slow down, lift power size and specimen bottle weight and position three will be coupled, should ensure that specimen bottle enters nest fast, again steadily " landing ", this just needs control to lift power with the alternately change of specimen bottle present position.The opening degree of suction control valve 402 and gas puff Z-pinch valve 408 is controlled, with this control and suck power and lift power by Programmable Logic Controller 6.
Above-mentioned Sample Storehouse 3 is by vertical central shaft, sample storage disk 301 is assembled up layer by layer, disk driving mechanism makes the original state of disk remain on sample delivery channel up/down perforation state all the time, when needs store certain sample to appointment sample nest, driving mechanism driver plate rotates, and allows this sample nest find nearest sample delivery channel.Other sample like this on same disk does not just need, in " exposure " environment beyond storage condition, to maintain the temperature of sample storage environment well.Leave appropriate gap between layers, accomplish sealing and do not interfere.This structure solves the sample problem in limited space more than storage as far as possible well and sample storage is flexible.
If get third layer (to arrange from bottom to top, the number of plies is greater than 3 layers), certain specimen bottle 11 on 2nd ring (from inside to outside arranging), then third layer sample storage disk rotates the sample delivery channel corresponding to the 2nd ring under the driving of driving mechanism (is unimpeded from the 4th layer to the bottom, first, two layers is also unimpeded, because be every layer sample delivery channel virgin state be all alignment), by lifting the suction with air intake duct 403 of lifting of air jet pipe 407, the sample storage disk 301 that specimen bottle 305 is removed, sample tray 204 is transported to through delivery pipe 310.Then this sample storage disk comes back to original state under the driving of driving mechanism, and namely the sample delivery channel of this layer aligns with the sample delivery channel of other layer.
Barcode scanner 5 is arranged on the path that sample is conveyed through, as in automatic access sluice gate 2, sample tray 204 place, the position such as delivery pipe two-port in sample automatic delivering mechanism.For sample identity identification and the corresponding sample nest 302 of searching, and be connected with host computer 7.
Sensor (Temperature Humidity Sensor, pressure transducer) in above-mentioned automatic access sluice gate 2, Sample Storehouse 3, sample automatic delivering mechanism 4, electric executing part (servomotor, operation valve etc.) are all connected with Programmable Logic Controller 6, and the program according to establishment in Programmable Logic Controller 6 is run according to condition and order.
Barcode scanner 5 is all connected with host computer 7 with Programmable Logic Controller 6, the main finishing man-machine interaction of host computer 7, steering order input and output, sample information collection, sample information record, data conversion, with the function such as Programmable Logic Controller 6 communication.Programmable Logic Controller 6 accepts the steering order that host computer 7 sends, and is automatically converted to corresponding control signal by certain logical relation, exports each topworks to.
Fig. 5 give specimen bottle 305 stored in process flow diagram, specimen bottle 305 posts in advance the label of band bar code, a kind of bar code information represents a kind of sample, and each sample nest 302 is a corresponding bar code information also, so just forms one-to-one relationship.Specimen bottle 305 stored in process is:
First by specimen bottle 305 through automatic access sluice gate 2, enter reefer, barcode scanner 5 carries out bar-code identification, and the bar code information of scanning is passed to host computer 7, host computer 7 store according to record and provide this specimen bottle 305 at Sample Storehouse 3 stored in position (number of plies of sample storage disk and the polar coordinates radius of sample nest position and polar angle); Sample Storehouse 3 and sample automatic delivering mechanism start, and the respective sample storage disk in Sample Storehouse 3 is rotated, make specimen bottle will stored in sample nest above and below sample delivery channel all align; Specimen bottle is delivered to air intake duct 403 through delivery pipe 410 simultaneously, enters sample delivery channel by air intake duct 403.Programmable Logic Controller 6 controls the opening degree of gas puff Z-pinch valve 408, the size of holder for regulating lifting force, specimen bottle is steadily arrived fast and specifies sample nest.
The process that specimen bottle 305 takes out is:
Programmable Logic Controller 6 reads the specimen bottle positional information (number of plies of place sample storage disk that host computer 7 records, and the sample nest position on this layer of sample storage disk), positional information is converted to locator data (the layer location of sample storage disk, the polar coordinates radius location of sample nest and polar angle location); Sample storage disk is according to instruction, rotate to assigned address, start sample automatic delivering mechanism 4, open got specimen bottle place sample nest corresponding lift gas puff Z-pinch valve 408 on air jet pipe 407 and air intake duct 403 and suction control valve 402, make specimen bottle be delivered to automatic access sluice gate 2 by delivery pipe 410 again, barcode scanner 5 carries out bar code scan, and the bar code recorded with host computer 7 is checked, after confirmation, taken out by automatic access sluice gate 2.If sample that this is undesirable, then original route returns, and again chooses.
Claims (3)
1. for the automatic control system of this refrigeration of medicine bioengineering medicine, comprise reefer, automatic access sluice gate, Sample Storehouse, sample automatic delivering mechanism, barcode scanner, Programmable Logic Controller and host computer, it is characterized in that: described reefer is an obturator, automatic access sluice gate is arranged on reefer sidewall, and Sample Storehouse and sample automatic delivering mechanism are all arranged in reefer; Barcode scanner is arranged on the path that sample is conveyed through; Sensor in automatic access sluice gate, Sample Storehouse and sample automatic delivering mechanism is all connected with Programmable Logic Controller with execution unit; Barcode scanner is all connected with host computer with Programmable Logic Controller;
Described automatic access sluice gate, it is the transition passage being used for accessing sample that reefer and space outerpace contact, flood tide gate is provided with between this transition passage and external environment condition, and be provided with interior automatically-controlled door between cold storage environment, a zone of transition is provided with between flood tide gate and interior automatically-controlled door, be provided with in zone of transition and the gas access of reefer ft connection and exhausr port, the cryogenic gas entrance be communicated with cooling compartment and protective gas entrance, these mouths are all provided with valve; Pressure transducer and Temperature Humidity Sensor is provided with in zone of transition; Arrange the sample tray of a movement in the inner side that interior automatically-controlled door is in reefer, the inner side of sample tray is provided with a delivery device;
Described Sample Storehouse, comprises central shaft, sample storage disk and disk driving mechanism, central shaft bottom is arranged on a pedestal, each sample storage disk is installed in parallel on central shaft, sealing gasket is provided with between adjacent sample storage disk, sample storage disk is distributed with sample nest and sample delivery channel, corresponding to all sample storage disks, a set of disk driving mechanism is at least set, disk driving mechanism is arranged on one and is fixed on the support of pedestal, sample nest adopts many form of annular rings to be arranged on sample storage disk, sample nest is circular distribution, number of rings is at least two rings, all annulus are concentric, each annulus is at least arranged a sample delivery channel,
Described sample automatic delivering mechanism, comprise lifting apparatus and absorption conveying device, lifting apparatus is arranged on the below of bottom sample storage disk, comprise and lift air jet pipe and gas puff Z-pinch valve, arrange one corresponding to each sample delivery channel on bottom sample storage disk and lift air jet pipe, lift on air jet pipe and be connected with gas puff Z-pinch valve, lift air jet pipe and be connected with source of the gas; Absorption conveying device is arranged on the top of most top layer sample storage disk, comprise combination air-breathing seat, air intake duct, suction control valve, delivery pipe, pipage control valve and vacuum storehouse, each sample delivery channel corresponded on most top layer sample storage disk arranges an air intake duct, air intake duct is connected with suction control valve, each air intake duct is all connected with vacuum storehouse, delivery pipe one end is connected with vacuum storehouse, and one end is connected to sample tray, delivery pipe is connected with pipage control valve.
2. the automatic control system for this refrigeration of medicine bioengineering medicine according to claim 1, is characterized in that: described sample tray is provided with LOAD CELLS.
3. the automatic control system for this refrigeration of medicine bioengineering medicine according to claim 1, it is characterized in that: described in state disk driving mechanism and comprise servomotor and gear train, servomotor is connected with the input end of gear train, and the output terminal of gear train connects on a rotary disc.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310336710.7A CN104345647A (en) | 2013-08-05 | 2013-08-05 | Automatic control system used for refrigeration of medical and biological medicines |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310336710.7A CN104345647A (en) | 2013-08-05 | 2013-08-05 | Automatic control system used for refrigeration of medical and biological medicines |
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| Publication Number | Publication Date |
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| CN104345647A true CN104345647A (en) | 2015-02-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310336710.7A Pending CN104345647A (en) | 2013-08-05 | 2013-08-05 | Automatic control system used for refrigeration of medical and biological medicines |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110425788A (en) * | 2019-07-18 | 2019-11-08 | 江苏领坤生物科技有限公司 | A kind of -20 degrees Celsius of full-automatic sample database refrigerators |
-
2013
- 2013-08-05 CN CN201310336710.7A patent/CN104345647A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110425788A (en) * | 2019-07-18 | 2019-11-08 | 江苏领坤生物科技有限公司 | A kind of -20 degrees Celsius of full-automatic sample database refrigerators |
| CN110425788B (en) * | 2019-07-18 | 2024-03-22 | 江苏领坤生物科技有限公司 | Full-automatic sample storehouse refrigerator of-20 degrees centigrade |
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| WD01 | Invention patent application deemed withdrawn after publication |