CN104337958A - Medicament for treating emphysema and preparation method thereof - Google Patents

Medicament for treating emphysema and preparation method thereof Download PDF

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Publication number
CN104337958A
CN104337958A CN201410628006.3A CN201410628006A CN104337958A CN 104337958 A CN104337958 A CN 104337958A CN 201410628006 A CN201410628006 A CN 201410628006A CN 104337958 A CN104337958 A CN 104337958A
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Prior art keywords
medicament
medicine
emophysematous
radix
emphysema
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CN201410628006.3A
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Chinese (zh)
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陈丽芳
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/342Adenophora
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884Arisaema, e.g. Jack in the pulpit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a medicament for treating emphysema. The medicament mainly comprises the Chinese herbal medicines of the root of straight ladybell, fineleaf schizonepeta herb, bile arisaema, red lead, Chinese magnoliavine fruit, coptidis rhizoma and the like as raw materials, wherein the Chinese herbal medicines are repeatedly decocted through slow fire; dregs of the decoction are taken out; the soup is mixed and placed in a casserole to decoct for 2-4 hours and is condensed into paste ; then conventional auxiliary materials are added to prepare a clinically acceptable medicament; the medicament is packed to obtain a finished product. The medicament has the effects of clearing heat, activating qi and promoting blood circulation to remove meridian obstruction, and can be used for treating various types of emphysema.

Description

One treats emophysematous medicine and preparation method thereof
Technical field
The present invention relates to one and treat emophysematous medicine, being related specifically to a kind of take Chinese herbal medicine as the emophysematous medicine for the treatment of prepared by raw material, the invention still further relates to the preparation method of this medicine.
Background technology
Emphysema are one of common pneumonopathy, mainly refer to the air flue elasticity attenuation of terminal bronchiole far-end, and excessive expansion, inflation and Pulmonary volume increase or simultaneously with the pathological state that airway walls is destroyed.Cardinal symptom be breathe hard, dyspnea, weak, weight loss, loss of appetite, upper abdomen distension, simultaneously with symptoms such as cough, expectorations.At present, treat emophysematous Western medicine a lot, but generally there is the shortcomings such as treatment cost is high, side effect is large.In addition, also have the emophysematous Chinese medicine of a lot for the treatment of, but great majority has the shortcoming such as therapeutic effect difference, treatment cycle length.
Summary of the invention
The present invention aims to provide the emophysematous medicine for the treatment of that a kind of cure rate is high, treatment cost is low, have no side effect.
The preparation method of this medicine is provided to be another goal of the invention of the present invention.
Medicine of the present invention is made up of the raw material of following mass ratio:
Radix Adenophorae (Radix Glehniae) 5-10 Herba Schizonepetae 10-20
Arisaema Cum Bile 5-20 Plumbum preparatium 12-25
Fructus Schisandrae Chinensis 8-15 Rhizoma Coptidis 3-10.
Specifically be made up of the raw material of following mass ratio:
Radix Adenophorae (Radix Glehniae) 7 Herba Schizonepetae 15
Arisaema Cum Bile 12 Plumbum preparatium 18
Fructus Schisandrae Chinensis 10 Rhizoma Coptidis 8.
The preparation method of medicine of the present invention is:
Radix Adenophorae (Radix Glehniae), Herba Schizonepetae, Arisaema Cum Bile, Plumbum preparatium, Fructus Schisandrae Chinensis and Rhizoma Coptidis are added the clear water of 60-100 weight portions, 0.5-1.5 hours at a simmer, after repeatedly decocting 3 times, take out medicinal residues, marmite is put in 3 medicinal liquid mixing and decocts 2-4 hours, concentration of liquid medicine is become paste, then adds customary adjuvant, make the medicament of clinical acceptance.
Have between each medicine in prescription of the present invention and be added complementary and synergism, heat clearing away promoting the circulation of QI, promoting blood circulation to remove obstruction in the collateral, can treat all kinds emphysema, and have no side effect.
The present invention is that inventor is through repeatedly studying, progressively improve, last successful a kind of curative effect treats emophysematous medicine preferably, for showing that medicine of the present invention is to emophysematous therapeutic effect, the present invention has carried out clinical observation to the emphysema patient that 195 examples take this medicine, and selection has emphysema patient 195 example of comparability as a control group.Treatment group patient takes medicine of the present invention every day three times, and the morning, noon and afternoon respectively once, once take 5 grams of medicines, and matched group patient takes the emophysematous oral drugs of conventional therapy.Treat after one month, therapeutic outcome is in table 1
Table 1 treatment group and treatment of control group result synopsis
Cure Effectively Cure rate Effective percentage
Treatment group 149 examples 161 examples 76.41% 82.56%
Matched group 91 examples 113 examples 46.67% 57.95%
Treatment group is compared matched group and is had higher cure rate and effective percentage, thinks thus, and Drug therapy emphysema of the present invention have good effect, and through the Ureteral Calculus of month, takes medicine of the present invention and do not occur any toxic and side effects.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, but does not form any limitation of the invention.
Embodiment 1
Raw material (kg) is prepared according to following weight:
Radix Adenophorae (Radix Glehniae) 0.7, Herba Schizonepetae 1.5, Arisaema Cum Bile 1.2, Plumbum preparatium 1.8, Fructus Schisandrae Chinensis 1.0 and Rhizoma Coptidis 0.8.
Above-mentioned 7.0kg Chinese herbal medicine is put into marmite, adds the clear water of 8.0kg, 0.5-1.5 hours at a simmer, after repeatedly decocting 3 times, take out medicinal residues, concentration of liquid medicine is become paste, then adds customary adjuvant, make the powder of clinical acceptance, after packaging, obtain finished product.
Embodiment 2
Raw material (kg) is prepared according to following weight:
Radix Adenophorae (Radix Glehniae) 0.8, Herba Schizonepetae 1.6, Arisaema Cum Bile 1.5, Plumbum preparatium 2.0, Fructus Schisandrae Chinensis 1.0 and Rhizoma Coptidis 0.7.
Above-mentioned 7.6kg Chinese herbal medicine is put into marmite, add the clear water of 8.0kg, 1.5 hours at a simmer, after repeatedly decocting 3 times, take out medicinal residues, marmite is put in 3 medicinal liquid mixing again and decocts 3 hours, concentration of liquid medicine is become paste, then the paste medicine of gained dried, grind, encapsulated, after packaging finished product.

Claims (3)

1. treat an emophysematous medicine, it is characterized in that described medicine is made up of the raw material of following mass ratio:
Radix Adenophorae (Radix Glehniae) 5-10 Herba Schizonepetae 10-20
Arisaema Cum Bile 5-20 Plumbum preparatium 12-25
Fructus Schisandrae Chinensis 8-15 Rhizoma Coptidis 3-10.
2. the emophysematous medicine for the treatment of according to claim 1, is characterized in that described medicine is made up of the raw material of following mass ratio:
Radix Adenophorae (Radix Glehniae) 7 Herba Schizonepetae 15
Arisaema Cum Bile 12 Plumbum preparatium 18
Fructus Schisandrae Chinensis 10 Rhizoma Coptidis 8.
3. the preparation method of the emophysematous medicine for the treatment of according to claim 1, it is characterized in that Radix Adenophorae (Radix Glehniae), Herba Schizonepetae, Arisaema Cum Bile, Plumbum preparatium, Fructus Schisandrae Chinensis and Rhizoma Coptidis are added the clear water of 60-100 weight portions by the method, 0.5-1.5 hours at a simmer, after repeatedly decocting 3 times, take out medicinal residues, marmite is put in 3 medicinal liquid mixing and decocts 2-4 hours, concentration of liquid medicine is become paste, then add customary adjuvant, make the medicament of clinical acceptance.
CN201410628006.3A 2014-11-11 2014-11-11 Medicament for treating emphysema and preparation method thereof Pending CN104337958A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410628006.3A CN104337958A (en) 2014-11-11 2014-11-11 Medicament for treating emphysema and preparation method thereof

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Application Number Priority Date Filing Date Title
CN201410628006.3A CN104337958A (en) 2014-11-11 2014-11-11 Medicament for treating emphysema and preparation method thereof

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105394843A (en) * 2015-12-25 2016-03-16 刘震 Novel antibacterial medicinal mask

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102078499A (en) * 2009-12-01 2011-06-01 赵莉 Chinese patent medicine for treating emphysema
CN103845521A (en) * 2012-11-30 2014-06-11 孙玉洁 Traditional Chinese medicine for treating partial lung qi deficiency type emphysema

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102078499A (en) * 2009-12-01 2011-06-01 赵莉 Chinese patent medicine for treating emphysema
CN103845521A (en) * 2012-11-30 2014-06-11 孙玉洁 Traditional Chinese medicine for treating partial lung qi deficiency type emphysema

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
易磊等编著: "《中国秘方大全》", 31 May 2013 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105394843A (en) * 2015-12-25 2016-03-16 刘震 Novel antibacterial medicinal mask

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Application publication date: 20150211

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