CN104324169A - Externally applied traditional Chinese medicine ointment for treating gouty arthritis - Google Patents

Externally applied traditional Chinese medicine ointment for treating gouty arthritis Download PDF

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Publication number
CN104324169A
CN104324169A CN201410637198.4A CN201410637198A CN104324169A CN 104324169 A CN104324169 A CN 104324169A CN 201410637198 A CN201410637198 A CN 201410637198A CN 104324169 A CN104324169 A CN 104324169A
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chinese medicine
ointment
traditional chinese
gouty arthritis
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宋爱民
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • A61K36/515Gentiana
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716Clematis (leather flower)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884Arisaema, e.g. Jack in the pulpit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to an externally applied traditional Chinese medicine ointment for treating gouty arthritis, and belongs to the technical field of traditional Chinese medicines. The ointment is composed of the following raw materials in parts by weight: 3 parts of rhizoma arisaematis, 3 parts of momordica cochinchinensis, 2 parts of sodium sulfate, 1 part of peach seeds, 1 part of gentian, 2 parts of radix angelicae dahuricae, 2 parts of clematis chinensis, and 1 part of rhizoma atractylodis. The ointment disclosed by the invention has the effects of clearing away heat and removing dampness, and promoting blood circulation to remove meridian obstruction, and has the characteristics that the ointment directly affects the affected site after being locally applied, takes effect quickly, has no toxic or side effect, and is high in curative effect, safe and reliable, and the like.

Description

The external application Chinese medicine unguentum for the treatment of gouty arthritis
Technical field
The invention belongs to field of traditional Chinese medicine technology, relate to a kind of external application Chinese medicine unguentum for the treatment of gouty arthritis.
Background technology
Gouty arthritis is modern medicine name, is because disorders of purine metabolism and blood uric acid continue higher, and urate deposition is at joint capsule, synovial bursa, cartilage and the inflammatory reaction that causes." gout " disease, had once done more detailed record in classical Chinese medicine, " danxi's experiential therapy gout " describes the symptom of gout for " it is also that extremity hundred joint is walked to lead to ", also points out " the severe and migratory arthralgia wind disease of other party meaning "." Elementary Medicine gout " thinks that gout is many by " vim and vigour asthenia not nutrition space between skin and muscles ".Red, swollen, hot with joint, bitterly clinically, recurrent exerbation, joint motion is dumb is main manifestations; Be principle for the treatment of clinically by dialectical removing damp-heat, the promoting blood circulation to remove obstruction in the collateral taked, have received good therapeutic effect.
Summary of the invention
The object of this invention is to provide a kind of external application Chinese medicine unguentum for the treatment of gouty arthritis, have instant effect, curative effect high, have no side effect, the feature such as safe ready.
The external application Chinese medicine unguentum for the treatment of gouty arthritis of the present invention, the weight of raw material of Chinese medicine consists of: Rhizoma Arisaematis 3 parts, Semen Momordicae 3 parts, 2 parts, Natrii Sulfas, 1 part, Semen Persicae, Radix Gentianae 1 part, the Radix Angelicae Dahuricae 2 parts, Radix Clematidis 2 parts and Rhizoma Atractylodis 1 part.
Preparation method: medicine-feeding is concocted qualified, weigh and assort, insert and decoct in container, add 30 parts, Oleum Sesami, fry one hour, filter and remove residue with slow fire; Medicine oil continuation slow fire is tempered one hour, from fire, add 10 parts, Plumbum preparatium, stir evenly into cream, the 7 days gas that reduces internal heat of harvesting and storing.
Usage and dosage: external, melts plaster with little fire during use, and get heavily about 15 grams of ointment and be applied in the Corii Bovis seu Bubali paper substrate cloth of 10 × 10cm size and stick affected part, within 3 days, changing dressings once, 21 days is a course for the treatment of.
Drug action mechanism in the present invention is as follows:
Rhizoma Arisaematis: drying dampness to eliminate phlegm, expelling wind to relieve convulsion, externally used detumescence pain relieving.
Semen Momordicae: externally used detumescence pain relieving.
Natrii Sulfas: under rushing down, hard masses softening and resolving, heat clearing away.
Semen Persicae: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.
Radix Gentianae: clearing away dryness wets, eliminating pathogen in the liver gallbladder fire.
The Radix Angelicae Dahuricae: the dispelling wind that induces sweat, understand things pain-stopping, dampness leukorrhagia stopping, detumescence and apocenosis.
Radix Clematidis: wind-damp dispelling, the meridian dredging, the bone that disappears are choked.
Rhizoma Atractylodis: drying damp and strengthening spleen, wind-damp dispelling.
According to compatibility the present invention with Rhizoma Arisaematis drying dampness to eliminate phlegm, reducing swelling and alleviating pain for monarch drug, Semen Momordicae dispersing swelling and dissipating binds, pain relieving are ministerial drug, and Natrii Sulfas, Semen Persicae, Radix Gentianae, the Radix Angelicae Dahuricae, Radix Clematidis, Rhizoma Atractylodis are adjuvant altogether.
Above all medicines cure mainly and effect is all referred to college of traditional Chinese medicine's undergraduate course teaching material " Chinese materia medica ", Science and Technology of Shanghai publishing house.
Below for clinical trial is summed up:
The symptom of gouty arthritis: joint is red, swollen, hot, bitterly, recurrent exerbation, joint motion is dumb, tenderness, common joint as: secondly Metatarsophalangeal joint is ankle, instep, knee joint, elbow and carpal joint, lab testing: blood uric acid increases.
Treatment standard:
Recovery from illness: clinical symptoms all disappears, joint motion is normal, chemical examination: blood uric acid is normal, erythrocyte sedimentation rate is normal.
Take a turn for the better: cardinal symptom obviously alleviates, and function of joint is progress obviously, chemical examination: blood uric acid is close to normal value.
Invalid: although arthralgia alleviates, joint function disturbance is not improved, chemical examination: blood uric acid reduces not obvious.
Usage and dosage: external, melts plaster with little fire during use, and get heavily about 15 grams of ointment and be applied in the Corii Bovis seu Bubali paper substrate cloth of 10 × 10cm size and stick affected part, within 3 days, changing dressings once, 21 days is a course for the treatment of.
Therapeutic outcome: clinical trial treatment gouty arthritis Patients with 300 Cases, after a course of therapy, recovery from illness 219 example, accounts for 73%, 57 examples that take a turn for the better, accounts for 19%, invalid 24 examples, accounts for 8%, total effective rate 92%.Shown in treating, without any side effects to patient, three large routine tests and hepatic and renal function detect no abnormal phenomenon.
Below enumerate several model case:
Case 1: patient appoints so-and-so, man, 40 years old, broke out between 2 day eve right lower extremity big toe joint red, swollen, hot, bitterly, tenderness, joint motion is dumb, and oral anti-inflammatory drug of being in is invalid, therefore in Lai Zhenwo institute August 7 in 2012, be diagnosed as gouty arthritis on inspection, fully recover after giving a course for the treatment of of Drug therapy of the present invention.
Case 2: patient Yang, man, 45 years old, the year before because of right lower extremity big toe arthralgia, institute of traditional Chinese medicine of Zeng county is diagnosed as gouty arthritis, weighs, do not heal so far time light during the state of an illness, this time cause exacerbation of symptoms because overworking, examine my institute in August, 2012, be diagnosed as gouty arthritis on inspection, fully recover after giving a course for the treatment of of Drug therapy of the present invention.
Case 3: patient Lee so-and-so, man, 50 years old, causeless burst joint, left lower extremity internal malleolus place is red, swollen, hot, bitterly; red scorching hot, the spasm of muscles and vessels of office's portion's inflammation, limitation of activity, examines my institute in August, 2012, be diagnosed as gouty arthritis on inspection, fully recover after giving a course for the treatment of of Drug therapy of the present invention.
The present invention compared with prior art, has following beneficial effect:
1. the Chinese medicine that the present invention selects all meets Pharmacopoeia of the People's Republic of China regulation, has effect of removing damp-heat, promoting blood circulation to remove obstruction in the collateral according to compatibility the present invention.
2. the present invention not only can treat gouty arthritis effectively, and also has good therapeutical effect to rheumatoid arthritis.
3. the present invention is dialectical accurately, compatibility is reasonable, local application, through sick institute, and instant effect, curative effect be high, have no side effect, safe ready.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment:
The weight of raw material of Chinese medicine consists of: Rhizoma Arisaematis 3 parts, Semen Momordicae 3 parts, 2 parts, Natrii Sulfas, 1 part, Semen Persicae, Radix Gentianae 1 part, the Radix Angelicae Dahuricae 2 parts, Radix Clematidis 2 parts and Rhizoma Atractylodis 1 part.
Preparation method: medicine-feeding is concocted qualified, weigh and assort, insert and decoct in container, add 30 parts, Oleum Sesami, fry one hour, filter and remove residue with slow fire; Medicine oil continuation slow fire is tempered one hour, from fire, add 10 parts, Plumbum preparatium, stir evenly into cream, the 7 days gas that reduces internal heat of harvesting and storing.
External, melts plaster with little fire during use, and get heavily about 15 grams of ointment and be applied in the Corii Bovis seu Bubali paper substrate cloth of 10 × 10cm size and stick affected part, within 3 days, changing dressings once, 21 days is a course for the treatment of.

Claims (1)

1. treat an external application Chinese medicine unguentum for gouty arthritis, it is characterized in that the weight of each raw material of Chinese medicine consists of: Rhizoma Arisaematis 3 parts, Semen Momordicae 3 parts, 2 parts, Natrii Sulfas, 1 part, Semen Persicae, Radix Gentianae 1 part, the Radix Angelicae Dahuricae 2 parts, Radix Clematidis 2 parts and Rhizoma Atractylodis 1 part.
CN201410637198.4A 2014-11-13 2014-11-13 Externally applied traditional Chinese medicine ointment for treating gouty arthritis Withdrawn CN104324169A (en)

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Application Number Priority Date Filing Date Title
CN201410637198.4A CN104324169A (en) 2014-11-13 2014-11-13 Externally applied traditional Chinese medicine ointment for treating gouty arthritis

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Application Number Priority Date Filing Date Title
CN201410637198.4A CN104324169A (en) 2014-11-13 2014-11-13 Externally applied traditional Chinese medicine ointment for treating gouty arthritis

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114306216A (en) * 2022-01-17 2022-04-12 郝博川 External ointment for relieving gouty arthritis pain and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114306216A (en) * 2022-01-17 2022-04-12 郝博川 External ointment for relieving gouty arthritis pain and preparation method thereof

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Application publication date: 20150204