CN104324158A - Complex with antioxidant auxiliary health function and capsule of complex - Google Patents
Complex with antioxidant auxiliary health function and capsule of complex Download PDFInfo
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- CN104324158A CN104324158A CN201410600740.9A CN201410600740A CN104324158A CN 104324158 A CN104324158 A CN 104324158A CN 201410600740 A CN201410600740 A CN 201410600740A CN 104324158 A CN104324158 A CN 104324158A
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- folium ginkgo
- vitis viniferae
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Abstract
The invention discloses a complex with an antioxidant auxiliary health function and a capsule of the complex. The main ingredients comprise the following components in parts by weight: 130-150 parts of a grape seed extract, 70-80 parts of a ginkgo biloba leaf extract, 40-60 parts of aloe barbadensis mill whole-leaf freeze-dried powder, 0.5-0.8 part of seleno-k-carrageenan and 300-320 parts of camellia oleifera seed oil. The complex disclosed by the invention has good antioxidant property, which is verified in animal experiments and human experiments, mice experiments prove that the level of MDA (malondialdehyde) dissolved in peripheral blood is in a decreasing trend, the animal experiments prove that the sample can increase the activity of SOD (superoxide dismutase) in serum of mice, and the human experiments prove that after the sample prepared by the invention is taken for trial, the activity of SOD and GSH-Px (glutathione peroxidase) in serum of a human body is significantly improved and the MDA in the serum is obviously reduced. The complex disclosed by the invention has the antioxidant function.
Description
Technical field
The present invention relates to Medicines and Health Product field, particularly a kind of complex and capsule thereof with non-oxidizability health-care assistance function.
Background technology
Antioxidation refers to the abbreviation of resisting oxidation free radical, English Anti-Oxidant.Human body, because of the continuous contact with the external world, comprises the factors such as breathing (oxidation reaction), outside contamination, radiation exposure and constantly produces in body
free radical.Scientific research shows, cancer, aging or Other diseases are mostly relevant with the generation of excessive free radicals.Effect of Anti oxidation effectively can overcome its harm brought, so the health product with antioxygenic property become one of Main way of at present research and development, non-oxidizability is also one of important functional requirements of health product.
Summary of the invention
In sum, the present invention is necessary to provide a kind of complex with non-oxidizability health-care assistance function.
Further, be necessary to provide a kind of capsule obtained by the above-mentioned complex with non-oxidizability health-care assistance function.
Have a complex for non-oxidizability health-care assistance function, its main component is made up of by its weight portion following component: Semen Vitis viniferae extract 130-150 part; Folium Ginkgo extract 70-80 part; Aloe vulgaris full leaf lyophilized powder 40-60 part; Selenocarrageenan 0.5-0.8 part; Camellia seed oil 300-320 part.
There is a complex for non-oxidizability health-care assistance function, be made up of by its weight portion following component: Semen Vitis viniferae extract 130-150 part; Folium Ginkgo extract 70-80 part; Aloe vulgaris full leaf lyophilized powder 40-60 part; Selenocarrageenan 0.5-0.8 part; Camellia seed oil 300-320 part; Purified water 90-110 part.
Wherein, the general flavone content of described complex is greater than 1.15wt%, and procyanidin is greater than 22.4wt%, and selenium is less than 0.002wt%.
Wherein, the above-mentioned formula with the complex of non-oxidizability health-care assistance function is preferably: Semen Vitis viniferae extract 135-145 part; Folium Ginkgo extract 73-77 part; Aloe vulgaris full leaf lyophilized powder 45-55 part; Selenocarrageenan 0.55-0.7 part; Camellia seed oil 305-315 part.
Wherein, the procyanidin content of described Semen Vitis viniferae extract is more than 95%.
Wherein, the general flavone content of described Folium Ginkgo extract is more than 10%.
Wherein, the content of described selenocarrageenan is below 1%.
Wherein, the extracting method of described Semen Vitis viniferae is as follows: cleaned by Semen Vitis viniferae after pulverizing and be soaked in water 0.5 hour, be heated to the lasting 0.6-0.8 hour that seethes with excitement, cooled and filtered, when being concentrated into 65 DEG C, relative density is the concentrated solution of 0.9-0.98, adding ethanol in proper amount makes alcohol content volume ratio reach 80%-85%, 0 DEG C of cold preservation more than 40 hours, filter, filtrate recycling ethanol is also concentrated into paste, lyophilization evacuation, obtains Semen Vitis viniferae extract.
Wherein, Folium Ginkgo extract method is as follows: described by 75%-95% alcoholic solution heating and refluxing extraction 2-4 time of dry Folium Ginkgo by 12 times amount, each 2h, filters, the residue medicinal residues after filtrate discards, add Folium Ginkgo weight 10-15 water heating and refluxing extraction doubly 2-4 time, each 1-1.5h, refilters, and filtrate is concentrated into paste, lyophilization evacuation, obtains Folium Ginkgo extract.
In addition, above-mentioned complex can obtain dosage form conventional on health product, as tablet, and capsule, oral liquid etc.
Wherein, the making raw material of capsule is Cera Flava, gelatin, purified water, glycerol, titanium dioxide, alkermes, and its preferential ratio is 15 parts, Cera Flava, 100 parts, gelatin, purified water 100 parts, glycerol 57 parts, titanium dioxide 1.2 parts, alkermes 0.3 part.
Compare prior art, complex of the present invention, there is good non-oxidizability, all be verified in zoopery and human experimentation, mouse experiment end hemolysate MDA level has reduction trend, and zoopery shows that sample has rising trend to mice serum SOD vigor, show in human experimentation, after the sample that test-meal the present invention is made, in human body, SOD in serum and GSH-Px vigor are significantly increased, and serum MDA has obvious reduction, and complex of the present invention has anti-oxidation function.
Detailed description of the invention
Below in conjunction with some detailed description of the invention, the present invention is described further.Specific embodiment is for further describing the present invention, non-limiting protection scope of the present invention.
Materials all in following examples, experimental example and comparative example is all from commercially available.
The assay method of total flavones: the method specified by " mensuration of total flavonoids in health food " in " health food inspection and assessment technical specification " 2003 editions measures.
The assay method of procyanidin: the method specified by " mensuration of health food procyanidins " in " health food inspection and assessment technical specification " 2003 editions measures.
The method that the mensuration of selenium: GB 5009.93 first specifies measures.
Malonaldehyde (MDA), superoxide dismutase (SOD), glutathion peroxidase (GSH-Px) detection method with being built up malonaldehyde (MDA) that Bioengineering Research Institute provides by Nanjing, superoxide dismutase (SOD), glutathion peroxidase (GSH-Px) test kit detect.
Embodiment 1
With Semen Vitis viniferae extract, Folium Ginkgo extract, the full leaf lyophilized powder of Aloe vulgaris, selenocarrageenan, camellia seed oil and making 5 kinds of complex, its cost-effectively formula is listed in form 1.Wherein, Semen Vitis viniferae extract is commercially available, and the content of its procyanidin lists in table 1 after testing, and Folium Ginkgo extract is commercially available, and the content of its total flavones lists in table 1 after testing, and selenocarrageenan is commercially available, and the content of its selenium lists in table 1 after testing.
Manufacture method is: Semen Vitis viniferae extract, Folium Ginkgo extract, the full leaf lyophilized powder of Aloe vulgaris, selenocarrageenan and camellia seed oil are mixed in proportion, obtained complex carries out zoopery and human experimentation.
Embodiment 2
With Semen Vitis viniferae extract, Folium Ginkgo extract, the full leaf lyophilized powder of Aloe vulgaris, selenocarrageenan, camellia seed oil and making 5 kinds of complex, its cost-effectively formula is listed in form 1.Wherein, Semen Vitis viniferae extract is commercially available, and the content of its procyanidin lists in table 1 after testing, and Folium Ginkgo extract is commercially available, and the content of its total flavones lists in table 1 after testing, and selenocarrageenan is commercially available, and the content of its selenium lists in table 1 after testing.
Manufacture method is: Semen Vitis viniferae extract, Folium Ginkgo extract, the full leaf lyophilized powder of Aloe vulgaris, selenocarrageenan and camellia seed oil are mixed in proportion, obtained complex carries out zoopery and human experimentation.
Embodiment 3
With Semen Vitis viniferae extract, Folium Ginkgo extract, the full leaf lyophilized powder of Aloe vulgaris, selenocarrageenan, camellia seed oil and making 5 kinds of complex, its cost-effectively formula is listed in form 1.Wherein, Semen Vitis viniferae extract is made by oneself, and the content of its procyanidin lists in table 1 after testing, and Folium Ginkgo extract is made by oneself, and the content of its total flavones lists in table 1 after testing, and selenocarrageenan is commercially available, and the content of its selenium lists in table 1 after testing.
The extracting method of Semen Vitis viniferae is as follows: cleaned by Semen Vitis viniferae after pulverizing and be soaked in water 0.5 hour, be heated to boiling and continue 0.8 hour, cooled and filtered, when being concentrated into 65 DEG C, relative density is the concentrated solution of 0.98, adds ethanol in proper amount and makes alcohol content volume ratio reach 85%, 0 DEG C of cold preservation more than 40 hours, filter, filtrate recycling ethanol is also concentrated into paste, and lyophilization evacuation, obtains Semen Vitis viniferae extract.
Described by the 95% alcoholic solution heating and refluxing extraction 2 time of dry Folium Ginkgo by 12 times amount, each 2h, filter, residue medicinal residues after filtrate discards, add the water heating and refluxing extraction 2 times of Folium Ginkgo weight 15 times, each 1-1.5h, refilter, filtrate is concentrated into paste, and lyophilization evacuation, obtains Folium Ginkgo extract.
Manufacture method is: Semen Vitis viniferae extract, Folium Ginkgo extract, the full leaf lyophilized powder of Aloe vulgaris, selenocarrageenan and camellia seed oil are mixed in proportion, obtained complex carries out zoopery and human experimentation.
Embodiment 4
With Semen Vitis viniferae extract, Folium Ginkgo extract, the full leaf lyophilized powder of Aloe vulgaris, selenocarrageenan, camellia seed oil and making 5 kinds of complex, its cost-effectively formula is listed in form 1.Wherein, Semen Vitis viniferae extract is made by oneself, and the content of its procyanidin lists in table 1 after testing, and Folium Ginkgo extract is made by oneself, and the content of its total flavones lists in table 1 after testing, and selenocarrageenan is commercially available, and the content of its selenium lists in table 1 after testing.
The extracting method of Semen Vitis viniferae is as follows: cleaned by Semen Vitis viniferae after pulverizing and be soaked in water 0.5 hour, be heated to boiling and continue 0.6 hour, cooled and filtered, when being concentrated into 65 DEG C, relative density is the concentrated solution of 0.9, adds ethanol in proper amount and makes alcohol content volume ratio reach 80%, 0 DEG C of cold preservation more than 40 hours, filter, filtrate recycling ethanol is also concentrated into paste, and lyophilization evacuation, obtains Semen Vitis viniferae extract.
Described by the 75% alcoholic solution heating and refluxing extraction 4 time of dry Folium Ginkgo by 12 times amount, each 2h, filter, residue medicinal residues after filtrate discards, add the water heating and refluxing extraction 4 times of Folium Ginkgo weight 10 times, each 1.5h, refilter, filtrate is concentrated into paste, and lyophilization evacuation, obtains Folium Ginkgo extract.
Manufacture method is: Semen Vitis viniferae extract, Folium Ginkgo extract, the full leaf lyophilized powder of Aloe vulgaris, selenocarrageenan and camellia seed oil are mixed in proportion, obtained complex carries out zoopery and human experimentation.
Embodiment 5
With Semen Vitis viniferae extract, Folium Ginkgo extract, the full leaf lyophilized powder of Aloe vulgaris, selenocarrageenan, camellia seed oil and making 5 kinds of complex, its cost-effectively formula is listed in form 1.Wherein, Semen Vitis viniferae extract is made by oneself, and the content of its procyanidin lists in table 1 after testing, and Folium Ginkgo extract is made by oneself, and the content of its total flavones lists in table 1 after testing, and selenocarrageenan is commercially available, and the content of its selenium lists in table 1 after testing.
The extracting method of Semen Vitis viniferae is as follows: cleaned by Semen Vitis viniferae after pulverizing and be soaked in water 0.5 hour, be heated to boiling and continue 0.6 hour, cooled and filtered, when being concentrated into 65 DEG C, relative density is the concentrated solution of 0.98, adds ethanol in proper amount and makes alcohol content volume ratio reach 85%, 0 DEG C of cold preservation more than 40 hours, filter, filtrate recycling ethanol is also concentrated into paste, and lyophilization evacuation, obtains Semen Vitis viniferae extract.
Described by the 95% alcoholic solution heating and refluxing extraction 3 time of dry Folium Ginkgo by 12 times amount, each 2h, filter, residue medicinal residues after filtrate discards, add the water heating and refluxing extraction 3 times of Folium Ginkgo weight 15 times, each 1h, refilter, filtrate is concentrated into paste, and lyophilization evacuation, obtains Folium Ginkgo extract.
Manufacture method is: Semen Vitis viniferae extract, Folium Ginkgo extract, the full leaf lyophilized powder of Aloe vulgaris, selenocarrageenan and camellia seed oil are mixed in proportion, obtained complex carries out zoopery and human experimentation.
Table 1
| Experimental example 1 | Experimental example 2 | Experimental example 3 | Experimental example 4 | Experimental example 5 | |
| Semen Vitis viniferae extract | 130 | 135 | 140 | 145 | 150 |
| Folium Ginkgo extract | 70 | 77 | 75 | 73 | 80 |
| The full leaf lyophilized powder of Aloe vulgaris | 40 | 45 | 50 | 55 | 60 |
| Selenocarrageenan | 0.5 | 0.55 | 0.6 | 0.7 | 0.8 |
| Camellia seed oil | 300 | 305 | 320 | 310 | 315 |
| Procyanidin content/the % of Semen Vitis viniferae extract | 95 | 95.5 | 96 | 96 | 96.5 |
| General flavone content/the % of Folium Ginkgo extract | 10 | 11 | 10.5 | 11 | 10 |
| Content/the % of selenocarrageenan | 0.6 | 1 | 0.8 | 0.8 | 0.9 |
Animal experiment method:
Laboratory animal: SPF level Kunming kind female 12 the monthly age mice, laboratory animal production licence number SCXK(Hunan) 2009-0012, feedstuff is provided by same unit.
Experimental situation condition: experiment condition is barrier environment, experimental session experimental situation temperature 22 DEG C-24 DEG C, temperature is 52%-56%.
Sample preparation:
The sample of embodiment is got 2g and is settled to 100ml with edible vegetable oil, mixing, for subsequent use.
Experimental technique: before test, at random 24 mices are divided into 6 groups, after mouse weights, tail point blood sampling 20 μ l add 0.48ml distilled water and make 4% molten remarks, measure the MDA level in hemolysate, and after the complex of embodiment 1-5 being made sample, difference gavage is to the mice of 1-5 group, 6th group compares group and gives isopyknic edible vegetable oil, every day gavage once, gavage volume is 0.1mg/10gbw, continuous 30 days.31st day, mice is as above adopted tail point blood and prepare 4% hemolysate, measure MDA, and pluck eyeball blood sampling, centrifugal, get serum, by kit measurement serum superoxide dismutases (SOD) and glutathion peroxidase (GSH-Px) vigor.
Table 2 sample is on the impact of Mouse Weight
| Group | Number of animals/only | Initial volume | Mid-term body weight | Latter stage body weight | Weightening finish |
| Matched group | 4 | 46.49±3.92 | 47.85±4.70 | 48.22±3.51 | 1.73±2.39 |
| 1st group | 4 | 47.77±3.95 | 48.67±4.55 | 49.32±3.96 | 1.55±3.31 |
| 2nd group | 4 | 47.83±4.17 | 48.39±4.52 | 50.00±4.79 | 2.17±2.46 |
| 3rd group | 4 | 47.87±2.85 | 48.60±2.87 | 49.90±3.34 | 2.03±3.10 |
| 4th group | 4 | 46.95±2.95 | 47.45±3.05 | 48.84±3.10 | 1.89±3.12 |
| 5th group | 4 | 47.13±3.01 | 48.03±2.85 | 49.08±2.78 | 1.95±2.98 |
The experiment of each group of mice is initial, experiment is compared matched group with the body weight that experiment terminates rear mice mid-term, there was no significant difference.
Table 3 sample is on the impact of mice MDA content
| Group | Number of animals/only | MDA content (nmol/ml4% hemolysate) before experiment | MDA content (nmol/ml4% hemolysate) after experiment |
| Matched group | 4 | 13.13±3.76 | 14.29±3.22 |
| 1st group | 4 | 13.06±3.54 | 10.73±4.06 |
| 2nd group | 4 | 13.01±3.48 | 10.89±3.98 |
| 3rd group | 4 | 12.98±3.32 | 10.67±3.87 |
| 4th group | 4 | 13.05±2.95 | 10.92±3.67 |
| 5th group | 4 | 13.10±3.01 | 10.95±3.46 |
Above-mentioned experiment shows that sample has reduction trend to mouse experiment end hemolysate MDA level.
Table 4 sample is on the impact of mice serum SOD vigor
| Group | Number of animals/only | SOD vigor (U/ml) |
| Matched group | 4 | 148.7±41.60 |
| 1st group | 4 | 180.73±56.42 |
| 2nd group | 4 | 182.77±56.85 |
| 3rd group | 4 | 184.50±55.43 |
| 4th group | 4 | 179.60±50.32 |
| 5th group | 4 | 183.87±54.68 |
Above-mentioned experiment shows that sample has rising trend to mice serum SOD vigor.
Human trial
Experimenter selects
Inclusive criteria: experimenter's male or female.At 45 1 65 years old age, physical condition is good, without obvious brain, the heart, liver, lung, kidney, Hematological Diseases, without Long-term taking medicine history volunteer and ensure cooperation.
Subject Exclusion Criteria: gestation or women breast-feeding their children; To health food allergy sufferers; Merge intentionally, liver, the serious disease patient such as kidney and hemopoietic system; Take the article relevant with tested function in a short time, have influence on result judgement person; Do not meet inclusive criteria, not by the edible given the test agent of regulation, effect or data not umbra sound effect or safety judgement person cannot be judged.
To inclusive criteria be met and ensure 30 volunteers of compatibility test, be divided into 6 groups at random, embodiment 1-5 sample is made respectively the capsule of every 0.6g effective ingredient, give tested group of the 1 to 5 group respectively to take, 6th group is matched group, tested group of matched group takes placebo, continuous 180 days.Duration of test does not change original dietary habit, normal diet.
Carry out serum MDA to before and after experimenter's test-meal, SOD, GSH-Px detect.
Calculate individual MDA, SOD, GSH-Px rate of change, adds up its meansigma methods and lists in table 5
LPO: the change of MDA and MDA rate of descent before and after viewing test.
MDA X 100% before MDA rate of descent=(test front MDA mono-and test rear MDA)/test
Superoxide dismutase: the change of SOD and the rate of rise of SOD before and after viewing test.
SOD X 100% before SOD rate of rise=(after test, SOD mono-tests front SOD)/test
The sweet skin peroxidase of paddy skin: the change of GSH-Px and the rate of rise of GSH-Px before and after viewing test.
GSH-Px X 100% before GSH-Px rate of rise=(after test, GSH-Px mono-tests front GSH-Px)/test
| Group | Number | MDA average rate of decrease/% | Average rate of rise/the % of SOD | Average rate of rise/the % of GSH-Px |
| Matched group | 5 | 0.34 | 1.22 | 0.97 |
| 1st group | 5 | 2.40 | 8.64 | 3.99 |
| 2nd group | 5 | 2.52 | 8.35 | 4.01 |
| 3rd group | 5 | 2.48 | 8.40 | 3.95 |
| 4th group | 5 | 2.45 | 8.66 | 4.19 |
| 5th group | 5 | 2.41 | 8.65 | 3.95 |
Experimenter takes tested material 180 days, and result shows, after the sample that test-meal the present invention is made, in human body, SOD in serum and GSH-Px vigor are significantly increased, and serum MDA has obvious reduction, and complex of the present invention has anti-oxidation function.
The foregoing is only embodiments of the invention; not thereby the scope of the claims of the present invention is limited; every utilize description of the present invention to do equivalent structure or equivalent flow process conversion; or be directly or indirectly used in other relevant technical fields, be all in like manner included in scope of patent protection of the present invention.
Claims (10)
1. have a complex for non-oxidizability health-care assistance function, its main component is made up of by its weight portion following component:
Semen Vitis viniferae extract 130-150 part;
Folium Ginkgo extract 70-80 part;
Aloe vulgaris full leaf lyophilized powder 40-60 part;
Selenocarrageenan 0.5-0.8 part;
Camellia seed oil 300-320 part.
2. there is a complex for non-oxidizability health-care assistance function, be made up of by its weight portion following component:
Semen Vitis viniferae extract 130-150 part;
Folium Ginkgo extract 70-80 part;
Aloe vulgaris full leaf lyophilized powder 40-60 part
Selenocarrageenan 0.5-0.8 part
Camellia seed oil 300-320 part
Purified water 90-110 part.
3. there is a complex for non-oxidizability health-care assistance function, it is characterized in that:
Semen Vitis viniferae extract 135-145 part;
Folium Ginkgo extract 73-77 part;
Aloe vulgaris full leaf lyophilized powder 45-55 part;
Selenocarrageenan 0.55-0.7 part;
Camellia seed oil 305-315 part.
4. the complex as described in any one of claims 1 to 3, is characterized in that:
The general flavone content of described complex is greater than 1.15wt%, and procyanidin is greater than 22.4wt%, and selenium is less than 0.002wt%.
5. the complex as described in any one of claims 1 to 3, is characterized in that:
The procyanidin content of described Semen Vitis viniferae extract is more than 95%.
6. the complex as described in any one of claims 1 to 3, is characterized in that:
The general flavone content of described Folium Ginkgo extract is more than 10%.
7. the complex as described in any one of claims 1 to 3, is characterized in that:
The content of described selenocarrageenan is below 1%.
8. the complex as described in any one of claims 1 to 3, is characterized in that:
The extracting method of described Semen Vitis viniferae is as follows: cleaned by Semen Vitis viniferae after pulverizing and be soaked in water 0.5 hour, be heated to the lasting 0.6-0.8 hour that seethes with excitement, cooled and filtered, when being concentrated into 65 DEG C, relative density is the concentrated solution of 0.9-0.98, adds ethanol in proper amount and makes alcohol content volume ratio reach 80%-85%, 0 DEG C of cold preservation more than 40 hours, filter, filtrate recycling ethanol is also concentrated into paste, and lyophilization evacuation, obtains Semen Vitis viniferae extract.
9. the complex as described in any one of claims 1 to 3, is characterized in that:
Folium Ginkgo extract method is as follows: described by 75%-95% alcoholic solution heating and refluxing extraction 2-4 time of dry Folium Ginkgo by 12 times amount, each 2h, filter, residue medicinal residues after filtrate discards, add Folium Ginkgo weight 10-15 water heating and refluxing extraction doubly 2-4 time, each 1-1.5h, refilter, filtrate is concentrated into paste, and lyophilization evacuation, obtains Folium Ginkgo extract.
10. there is a complex for non-oxidizability health-care assistance function, it is characterized in that effective ingredient is complex described in any one of claim 1-9.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107260908A (en) * | 2017-06-01 | 2017-10-20 | 中山大学 | It is a kind of that there is the composition for promoting internal lead-eliminating effect |
| CN108041600A (en) * | 2017-12-18 | 2018-05-18 | 苏州诺衡生命科技有限公司 | A kind of formula and preparation method of comprehensive antioxidant functional food |
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| CN1660224A (en) * | 2004-12-24 | 2005-08-31 | 陕西爱波卓科技有限责任公司 | High preformance oxidation resistant combination extracted from plants |
| CN102216318A (en) * | 2008-11-19 | 2011-10-12 | 森永乳业株式会社 | Antioxidant |
| CN102318818A (en) * | 2011-08-11 | 2012-01-18 | 通化腾龙生物科技有限公司 | Health product of oligomeric proantho cyanidins and seleno-k-carrageenan |
| CN103142451A (en) * | 2013-04-03 | 2013-06-12 | 长沙理工大学 | Lip protector containing oil-tea camellia seed oil |
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- 2014-10-31 CN CN201410600740.9A patent/CN104324158A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660224A (en) * | 2004-12-24 | 2005-08-31 | 陕西爱波卓科技有限责任公司 | High preformance oxidation resistant combination extracted from plants |
| CN102216318A (en) * | 2008-11-19 | 2011-10-12 | 森永乳业株式会社 | Antioxidant |
| CN102318818A (en) * | 2011-08-11 | 2012-01-18 | 通化腾龙生物科技有限公司 | Health product of oligomeric proantho cyanidins and seleno-k-carrageenan |
| CN103142451A (en) * | 2013-04-03 | 2013-06-12 | 长沙理工大学 | Lip protector containing oil-tea camellia seed oil |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107260908A (en) * | 2017-06-01 | 2017-10-20 | 中山大学 | It is a kind of that there is the composition for promoting internal lead-eliminating effect |
| CN108041600A (en) * | 2017-12-18 | 2018-05-18 | 苏州诺衡生命科技有限公司 | A kind of formula and preparation method of comprehensive antioxidant functional food |
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