CN104306873A - 一种治疗颈肩综合症的中药制剂及其制备方法 - Google Patents

一种治疗颈肩综合症的中药制剂及其制备方法 Download PDF

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CN104306873A
CN104306873A CN201410491696.2A CN201410491696A CN104306873A CN 104306873 A CN104306873 A CN 104306873A CN 201410491696 A CN201410491696 A CN 201410491696A CN 104306873 A CN104306873 A CN 104306873A
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黄厚生
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Abstract

一种治疗颈肩综合症的中药制剂及其制备方法，涉及一种中药制剂，该中药制剂由以下重量的原料药组成，姜活13-17克、桂枝8-12克、威灵仙13-17克、白芍10-14克、当归10-14克、川芎8-12克、黄芪18-22克、熟地13-17克、姜黄10-14克、土鳖虫8-12克、全蝎8-12克、茯苓13-17克、白术13-17克、山茱萸13-17克、麦蓝菜8-12克、炒神曲8-14克、甘草4-8克。本发明的有益效果是：本发明提供的治疗颈肩综合症的中药制剂及其制备方法具有用药准确、吸收性强、有效成分含量高的特点，疗效显著，不易复发，治疗周期短，使用方法简便易行，原料易得，价格低廉，无毒副作用。

Description

一种治疗颈肩综合症的中药制剂及其制备方法
技术领域
本发明涉及中草药技术领域，具体涉及一种治疗颈肩综合症的中药制剂及其制备方法。
背景技术
颈肩综合征，乃是颈部、肩部，以至臂肘的肌筋并联发生酸软、痹痛、乏力感，及功能障碍等临床表现的病症。本症多于肩周炎基础上累及演进形成，好发于中老年人，以女性的发病率较高。尚缺乏特效治疗，故病程迁延，是临床常见的难治病之一。
目前，在临床中对于颈肩综合症治疗通常采用口服药物，口服药对胃肠道的刺激较大，患者难以忍受，且对肝、肾产生不同程度的损伤。现有的一些用于治疗颈肩综合症的中药制剂的使用效果均不够理想，其主要原因是：原料选择不够精确、药物中的有效成分含量低、药物的吸收性不佳。
发明内容
本发明所要解决的技术问题在于提供一种用料准确、且有效成分含量高、吸收性好的治疗颈肩综合症的中药制剂及其制备方法。
本发明所要解决的技术问题采用以下技术方案来实现：
一种治疗颈肩综合症的中药制剂，由以下重量的原料药组成：
姜活13-17克、桂枝8-12克、威灵仙13-17克、白芍10-14克、当归10-14克、川芎8-12克、黄芪18-22克、熟地13-17克、姜黄10-14克、土鳖虫8-12克、全蝎8-12克、茯苓13-17克、白术13-17克、山茱萸13-17克、麦蓝菜8-12克、炒神曲8-14克、甘草4-8克。
各原料药的优选重量为，
姜活14-16克、桂枝9-11克、威灵仙14-16克、白芍11-13克、当归11-13克、川芎9-11克、黄芪19-21克、熟地14-16克、姜黄11-15克、土鳖虫9-11克、全蝎9-11克、茯苓14-16克、白术14-16克、山茱萸14-16克、麦蓝菜9-11克、炒神曲9-11克、甘草5-7克。
各原料药的优选重量为，
姜活15克、桂枝10克、威灵仙15克、白芍12克、当归12克、川芎10克、黄芪20克、熟地15克、姜黄12克、土鳖虫10克、全蝎10克、茯苓15克、白术15克、山茱萸15克、麦蓝菜10克、炒神曲10克、甘草6克。
本发明的另一个目的是提供一种制备本发明中药制剂的方法，包括以下步骤：
1)按如下重量称取各原料药：
姜活13-17克、桂枝8-12克、威灵仙13-17克、白芍10-14克、当归10-14克、川芎8-12克、黄芪18-22克、熟地13-17克、姜黄10-14克、土鳖虫8-12克、全蝎8-12克、茯苓13-17克、白术13-17克、山茱萸13-17克、麦蓝菜8-12克、炒神曲8-14克、甘草4-8克；
将上述原料药清洗后混入水中浸泡25-30分钟，然后放入煎煮器皿中加入水1000ml，用文火加热煮沸，再煎熬20分钟后去渣取汁，得到药液。
用法与用量：将上述药液每日煎煮一剂，分为两次早晚各服用一次，15天为一个疗程。
本发明中：
姜活：性味：味辛，性温。归经：脾；胃；肝经。功效：温胃散寒，消食止痛功效。主治：温中消食；散寒止痛；活血；止咳平喘。主胃寒冷痛；噎膈吐逆；腹痛泄泻消化不良；风湿关节冷痛；跌打损伤；风寒咳喘。
桂枝：性味：味辛；甘；性温。归经：膀胱经；心经；肺经。功效：散寒解表；温通经脉；促阳化气。主治：风寒表证；寒湿痹痛；四肢厥冷；经闭痛经；癥瘕结块；胸痹；心悸；痰饮；小便不利。
威灵仙：性味：味辛、咸，性温。归经：膀胱经、肝经。功效：祛风除湿，通络止痛。主治：风湿痹痛，肢体麻木，筋脉拘挛，屈伸不利，骨哽咽喉。
白芍：性味：味苦酸，微寒归经：入肝、脾经。功能：补血柔肝、平肝止痛。敛阴收汗等。主治：胸腹胁肋疼痛，泻痢腹痛，自汗盗汗，阴虚发热，月经不调，崩漏，带下。
当归：性味：味甘；辛；苦；性温。归经：归肝经；心经；脾经。功能：补血；活血；调经止痛；润燥滑肠。主治：血虚诸证；月经不调；经闭；痛经；癥瘕结聚；崩漏；虚寒腹痛；痿痹；肌肤麻木；肠燥便难；赤痢后重；痈疽疮疡；跌扑损伤。
川芎：性味：味辛，性温。归经：归肝、胆、心包经。功能：活血祛瘀；行气开郁；祛风止痛。主治：治疗头痛之首选药物。月经不调；经闭痛经；产后瘀滞腥痛；症瘕肿块；胸胁疼痛；头痛眩晕；风寒湿痹；跌打损伤；痈疽疮疡。
黄芪：性味：味甘，性温。归经：肺经、脾经。功效：补气固表，利尿消肿，托毒排脓，敛疮生肌。主治：气虚乏力，食少便溏，中气下陷，久泻脱肛，便血崩漏，表虚自汗，气虚水肿，痈疽难溃，久溃不敛，血虚痿黄，内热消渴；慢性肾炎蛋白尿，糖尿病。
熟地：性味：味甘，性微温。归经：归肝、肾经。功能：补血养阴，填精益髓。主治：血虎萎黄；眩晕心悸；月经不调；崩不止；肝肾阴亏；潮热盗汗；遗精阳痿；不育不孕；腰膝酸软；耳鸣耳聋；头目昏花；须发早白；消渴；便秘；肾虚喘促。
姜黄：性味：味苦；辛；性温。归经：脾经；肝经。功效：破血行气；通经止痛。主治：血瘀气滞诸证；胞腹胁痛；妇女痛经；闭经；产后瘀滞腹痛；风湿痹痛；跌打损伤；痈肿。
土鳖虫：性味：味咸；性寒。归经：肝经。功效：破血逐瘀；续筋接骨。主治：血瘀经闭，癥瘕积块；跌打瘀肿；筋骨骨折；木舌重舌。
全蝎：性味：味辛；性平。归经：肝经。功效：祛风止痉；通络止痛；玫毒散结。主治：小儿惊风；抽搐痉挛；中风口半身不遂；破伤风；风湿顽痹；偏正头痛；牙痛；耳聋；痈肿疮毒；瘰疬痰核；蛇咬伤；烧伤；风疹；顽癣。
茯苓：性味：味甘、淡，性平。归经：心经、肺经、脾经、肾经。功效：利水渗湿，健脾化痰，宁心安神，败毒抗癌。主治：小便不利；水肿胀满；痰饮咳逆；呕吐；脾虚食少；泄泻；心悸不安；失眠健忘；遗精白浊。
白术：性味：味苦；酸；性微寒。归经：肝经；脾经。功效：养血和营；缓急止痛；敛阴平肝。主治：主月经不调；经行腹痛；崩漏；自汗；盗汗；胁肋脘腹疼痛；四肢挛痛；头痛；眩晕。
山茱萸：性味：味酸、涩，性微温。归经：肝、肾经。功效：补益肝肾，收敛固涩固精缩尿止带止崩止汗。主治：腰膝酸痛头晕耳鸣，健忘遗精滑精，遗尿尿频，崩漏带下月经不调，大汗虚脱，内热消渴。
麦蓝菜：性味：味苦；性平。归经：肝经；胃经。功效：活血通经；不乳消痈。主治：妇女经行腹痛；经闭；乳汁不通；乳痈；痈肿。
炒神曲：性味：味甘辛，性温。归经：脾、胃经。功效：健脾消食，理气化湿，解表，主治：伤食胸痞，腹痛吐泻，痢疾，感冒头痛，小儿伤饥失饱。
甘草：性味：味甘，性平。归经：归心经、肺经、脾经、胃经。功能：益气补中，清热解毒，祛痰止咳，缓急止痛，调和药性。主治：脾气虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，热毒疮疡，咽喉肿痛，药物、食物中毒；缓和药物烈性、毒性。
本发明的有益效果是：本发明提供的治疗颈肩综合症的中药制剂及其制备方法具有用药准确、吸收性强、有效成分含量高的特点，疗效显著，不易复发，治疗周期短，使用方法简便易行，原料易得，价格低廉，无毒副作用。
具体实施方式
为了使本发明实现的技术手段、创作特征、达成目的与功效易于明白了解，下面结合具体实施例，进一步阐述本发明。
实施例1
一种治疗颈肩综合症的中药制剂及其制备方法，称取姜活13-17克、桂枝8-12克、威灵仙13-17克、白芍10-14克、当归10-14克、川芎8-12克、黄芪18-22克、熟地13-17克、姜黄10-14克、土鳖虫8-12克、全蝎8-12克、茯苓13-17克、白术13-17克、山茱萸13-17克、麦蓝菜8-12克、炒神曲8-14克、甘草4-8克。
将上述原料药清洗后混入水中浸泡25-30分钟，然后放入煎煮器皿中加入水1000ml，用文火加热煮沸，再煎熬20分钟后去渣取汁，得到药液。
用法与用量：将上述药液每日煎煮一剂，分为两次早晚各服用一次，15天为一个疗程。
实施例2
一种治疗颈肩综合症的中药制剂及其制备方法，称取姜活15克、桂枝10克、威灵仙15克、白芍12克、当归12克、川芎10克、黄芪20克、熟地15克、姜黄12克、土鳖虫10克、全蝎10克、茯苓15克、白术15克、山茱萸15克、麦蓝菜10克、炒神曲10克、甘草6克。
将上述原料药清洗后混入水中浸泡25-30分钟，然后放入煎煮器皿中加入水1000ml，用文火加热煮沸，再煎熬20分钟后去渣取汁，得到药液。
用法与用量：将上述药液每日煎煮一剂，分为两次早晚各服用一次，15天为一个疗程。
为了更好的验证本发明的疗效，以下通过疗效组、对照组的对比实验，来进一步说明本发明提供的中药制剂对颈肩综合症的有益效果。
1、分组及治疗方法
1.1、分组，按就诊时间先后将患者随机分为治疗组和对照组，治疗组54例，对照组51例；
1.2、治疗组，使用本发明提供的中药制剂对颈肩综合症患者进行治疗；
1.3、对照组，市售的颈复康对颈肩综合症患者进行治疗；
1.4、疗程，治疗组和对照组均15天为一疗程。
1、治疗组和对照组的相关资料。
2.1、性别分布见表一：
表一
组别 例数 男 女
治疗组 54 38 16
对照组 51 30 21
2.2、年龄分布见表二
表二
组别 例数 40岁以下 41-60岁 60岁以上
治疗组 54 32 6 16
对照组 51 26 5 20
2.3、病程情况见表三
表三
组别 例数 2年以下 3-5年 6-10年 10年以上
治疗组 54 3 32 11 8
对照组 51 4 26 12 9
3、疗效评定标准
3.1、治愈，症状消失，实验室检查多次正常。
3.2、好转，主要症状及有关实验室检查有改善。
3.3、未愈，症状及实验室检查无变化。
2、实验结果(3个疗程后)见表5
表五
组别 例数 治愈 好转 未愈 总有效率％
治疗组 54 10 39 5 90.7％
对照组 51 7 35 9 82.4％
由以上实验可以看出，本发明提供的中药组合物对于治疗颈肩综合症具有较显著的疗效。
以上显示和描述了本发明的基本原理和主要特征和本发明的优点。本行业的技术人员应该了解，本发明不受上述实施例的限制，上述实施例和说明书中描述的只是说明本发明的原理，在不脱离本发明精神和范围的前提下，本发明还会有各种变化和改进，这些变化和改进都落入要求保护的本发明范围内。本发明要求保护范围由所附的权利要求书及其等效物界定。

Claims (4)

1.一种治疗颈肩综合症的中药制剂，其特征在于：该中药制剂由以下重量的原料药组成，
姜活13-17克、桂枝8-12克、威灵仙13-17克、白芍10-14克、当归10-14克、川芎8-12克、黄芪18-22克、熟地13-17克、姜黄10-14克、土鳖虫8-12克、全蝎8-12克、茯苓13-17克、白术13-17克、山茱萸13-17克、麦蓝菜8-12克、炒神曲8-14克、甘草4-8克。
2.根据权利要求1所述的治疗颈肩综合症的中药制剂，其特征在于：优选的中药制剂由以下重量的原料药组成：
姜活14-16克、桂枝9-11克、威灵仙14-16克、白芍11-13克、当归11-13克、川芎9-11克、黄芪19-21克、熟地14-16克、姜黄11-15克、土鳖虫9-11克、全蝎9-11克、茯苓14-16克、白术14-16克、山茱萸14-16克、麦蓝菜9-11克、炒神曲9-11克、甘草5-7克。
3.根据权利要求1所述的一种治疗颈肩综合症的中药制剂，其特征在于：优选的中药制剂由以下重量的原料药组成：
姜活15克、桂枝10克、威灵仙15克、白芍12克、当归12克、川芎10克、黄芪20克、熟地15克、姜黄12克、土鳖虫10克、全蝎10克、茯苓15克、白术15克、山茱萸15克、麦蓝菜10克、炒神曲10克、甘草6克。
4.一种制备权利要求1-3任一项所述的治疗颈肩综合症的中药制剂的方法，其特征在于：包括以下步骤，
a.按所述重量称取各味原料药；
b.将上述原料药清洗后混入水中浸泡25-30分钟，然后放入煎煮器皿中加入水1000ml，用文火加热煮沸，再煎熬20分钟后去渣取汁，得到药液。
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