CN104306635A - Traditional Chinese medicine for treating thyroid enlargement - Google Patents

Traditional Chinese medicine for treating thyroid enlargement Download PDF

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Publication number
CN104306635A
CN104306635A CN201410553305.5A CN201410553305A CN104306635A CN 104306635 A CN104306635 A CN 104306635A CN 201410553305 A CN201410553305 A CN 201410553305A CN 104306635 A CN104306635 A CN 104306635A
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parts
herba
traditional chinese
chinese medicine
rhizoma
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CN201410553305.5A
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崔楠楠
赵虹
王海亮
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/58Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Abstract

The invention relates to the field of formulae of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine for treating thyroid enlargement. The traditional Chinese medicine is characterized by being prepared from the following medicinal raw materials in parts by weight: 15-20 parts of dioscorea bulbifera, 10-15 parts of acanthus ilicifolius, 8-12 parts of Chinese forgetmenot root, 10-12 parts of rhizoma belamcandae, 10-15 parts of spreading hedyotis, 6-10 parts of honewort, 20-25 parts of symplocos lancifolia, 6-8 parts of honeysuckle stem, 10-12 parts of radices lithospermi, 12-15 parts of persian veronica, 15-20 parts of inula flower, 8-10 parts of fructus citri, 12-16 parts of melia toosendan, 6-10 parts of sculellaria barbata, 15-20 parts of pyrrosia lingua, 16-18 parts of pyrola, 12-16 parts of rhizoma curculiginis, 3-5 parts of pothos chinensis and 3-5 parts of tribulus terrestris. The 19 medicinal raw materials are soaked by water and decocted, and residues are removed to obtain filtrate. The traditional Chinese medicine has the effects of softening hard lumps, dispelling nodes, activating blood circulation to remove stasis and the like, can be used for radically treating patients with thyroid enlargement, and has good curative effect and no toxic or side effect, patients can recover quickly, and relapse can be prevented.

Description

Be used for the treatment of the Chinese medicine of thyromegaly
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine being used for the treatment of thyromegaly.
Background technology
As everyone knows, goiter refers to the goiter that benign thyroid epithelial cell hyperplasia is formed, and is the modal clinical manifestation of thyroid disease.In recent years, the sickness rate of primary disease and diagnosis constantly rise.Can peripheral organs be oppressed when goiter disease is serious, easily cause diet and dyspnea.At present, generally operative treatment is adopted to the Therapeutic Method of this disease, but often there is the decline of thyroid function in Post operation, even can leave permanent cicatrix.Clinician commonly uses levothyrocine treatment goiter, but curative effect is slow, the course for the treatment of is long, DeGrain.
Summary of the invention
Object of the present invention is exactly to overcome above-mentioned existing technical deficiency, provides a kind of Chinese medicine being used for the treatment of thyromegaly, has the effect such as hard masses softening and resolving, blood circulation promoting and blood stasis dispelling, thorough to goiter patient treatment, good effect, has no side effect, Rehabilitation is fast, not easily recurs.
The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of Chinese medicine being used for the treatment of thyromegaly, it is characterized in that being made up of the crude drug of following weight portion, Rhizoma Dioscoreae Bulbiferae 15 ~ 20, mouse muscle 10 ~ 15, Rhizoma seu Herba Elatostematis stewardii 8 ~ 12, Rhizoma Belamcandae 10 ~ 12, Radix Linderae Chunii 10 ~ 15, Herba abutili indici 6 ~ 10, cutter ash tree 20 ~ 25, Caulis Lonicerae 6 ~ 8, Radix Arnebiae (Radix Lithospermi) 10 ~ 12, Herba Veronicae Persicae 12 ~ 15, Flos Inulae 15 ~ 20, Fructus Citri 8 ~ 10, Fructus Toosendan 12 ~ 16, Herba Scutellariae Barbatae 6 ~ 10, Folium Pyrrosiae 15 ~ 20, Herba Pyrolae 16 ~ 18, Rhizoma Curculiginis 12 ~ 16, Herba Pothi Chinensis 3 ~ 5, Fructus Tribuli 3 ~ 5, above-mentioned 19 taste crude drug are soaked in water, to remove slag after decocting to obtain filtrate.
The invention has the beneficial effects as follows to have the effect such as hard masses softening and resolving, blood circulation promoting and blood stasis dispelling, thorough to goiter patient treatment, good effect, has no side effect, and Rehabilitation is fast, not easily recurs.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1:
Rhizoma Dioscoreae Bulbiferae, mouse muscle, Rhizoma seu Herba Elatostematis stewardii, Rhizoma Belamcandae, Radix Linderae Chunii, Herba abutili indici, cutter ash tree, Caulis Lonicerae, Radix Arnebiae (Radix Lithospermi), Herba Veronicae Persicae, Flos Inulae, Fructus Citri, Fructus Toosendan, Herba Scutellariae Barbatae, Folium Pyrrosiae, Herba Pyrolae, Rhizoma Curculiginis, Herba Pothi Chinensis, Fructus Tribuli is adopted to be that crude drug is prepared from.The every auxiliary medicine of its component (weight portion) is Rhizoma Dioscoreae Bulbiferae 18, mouse muscle 13, Rhizoma seu Herba Elatostematis stewardii 10, Rhizoma Belamcandae 11, Radix Linderae Chunii 12, Herba abutili indici 8, cutter ash tree 22, Caulis Lonicerae 7, Radix Arnebiae (Radix Lithospermi) 11, Herba Veronicae Persicae 13, Flos Inulae 17, Fructus Citri 9, Fructus Toosendan 14, Herba Scutellariae Barbatae 8, Folium Pyrrosiae 17, Herba Pyrolae 17, Rhizoma Curculiginis 14, Herba Pothi Chinensis 4, Fructus Tribuli 4.Getting above-mentioned 19 taste crude drug gross weights is 230 grams, add water 1100-1200ml, soaks 4-5 hour, then boil slow fire with high heat and decoct to about 60 minutes, remove slag to obtain filtrate about 200ml, medicinal residues add water about 300-400ml again, and decoct about 30 minutes, remove slag to obtain filtrate about 100ml, be total to obtain about 300ml medicine juice, i.e. obtained decoction of the present invention, load in sterile glass vials, seal bottle cap is for subsequent use.Every day 1 dose point sooner or later 2 times oral.
Rhizoma Dioscoreae Bulbiferae of the present invention is used for laryngopharynx swelling and pain, carbuncle sore tumefacting virus, snake bite and insect sting, goiter, haematemesis, spitting of blood; Mouse muscle heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, relieving cough and asthma.For lymphadenectasis, acute hepatitis, chronic hepatitis, hepatosplenomegaly, stomachache, cough, asthma; Rhizoma seu Herba Elatostematis stewardii can control traumatic injury, has curing rheumatism, restores menstrual flow and invigorates blood circulation, effect of detoxicating, relieving inflammation, and three tastes are monarch drug altogether; Rhizoma Belamcandae energy heat-clearing and toxic substances removing, eliminating stagnation antiinflammatory, reducing swelling and alleviating pain, relieving cough and resolving phlegm, be used for the treatment of tonsillitis and lumbago; Radix Linderae Chunii heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.For furuncle toxic swelling, jaundice due to damp-heat, the diseases such as dysuria, two tastes help monarch, are ministerial drug altogether; Assistant is with Herba abutili indici heat clearing away, and dampness removing, has one's ideas straightened out, and invigorates blood circulation.Control and have loose bowels, gonorrhea, Hiccough and deaf, hernia, carbuncle, urticaria; Cutter ash tree hemostasia and promoting granulation, and liver spleen.Main traumatic hemorrhage, spits blood, spitting of blood, furuncle, infantile malnutrition; Caulis Lonicerae has heat-clearing and toxic substances removing, the curative effect of dispelling wind dredging collateral.Can be used for epidemic febrile disease heating, sore and toxic, toxic-heat and blood stasis, beriberoid pyretic arthralgia; Radix Arnebiae (Radix Lithospermi) removing heat from blood, invigorates blood circulation, heat clearing away, removing toxic substances.Control warm macule, jaundice due to damp-heat, purpura, tell, be defeated in battle, hematuria, stranguria with turbid discharge, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer; Herba Veronicae Persicae expelling wind and removing dampness, strong waist, preventing the attack (or recurrence) of malaria.Cure mainly rheumatic arthralgia, lumbago due to renal deficiency, outer malaria; Flos Inulae sending down the abnormal ascending QI, expectorant, row water, preventing or arresting vomiting.For cough due to wind and cold, phlegm retention stores knot, chest and diaphragm feeling of fullness, dyspnea and cough with excessive sputum, vomiting eructation, epigastric oppression and rigidity; Fructus Citri has depressed liver-energy dispersing and QI regulating, and the chest stuffiness relieving reduces phlegm, dehumidifying and in, cure mainly distending pain in the chest and hypochondrium, cough with copious phlegm, gastral cavity abdomen painful abdominal mass pain, dyspepsia vomiting; Fructus Toosendan has soothing liver-QI promoting the circulation of QI to relieve pain, the drug effect of anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation; Herba Scutellariae Barbatae has removing pathogenic heat from blood and toxic substance from the body, eliminating stasis to stop pain, effect of detumescence and clearing away heat-damp and promoting diuresis; The effects such as Folium Pyrrosiae has relieving stranguria by diuresis, lung heat clearing expels the heat-evil.Can clearing away damp-heat, diuresis be led to beautiful jade, are controlled knife injury, scald, de-power is deficient; Herba Pyrolae wind-damp dispelling, bone and muscle strengthening, hemostasis.For rheumatic arthralgia, weakness of the waist and knees, menorrhagia, chronic cough due to asthenia of viscera; Rhizoma Curculiginis the kidney warming sun is strong, dispels cold-damp.Main sexual impotence cold sperm, urinary incontinence, coldness and pain in the epigastrium, soreness of waist and knee joint, muscles and bones is weak, lower limb contracture, climacteric syndrome; Herba Pothi Chinensis expelling wind and removing dampness, promoting blood circulation to remove blood stasis, removing food stagnancy, cough-relieving.For traumatic injury, advanced schistosomiasis hepatosplenomegaly, rheumatic arthritis; Fructus Tribuli suppressing the hyperactive liver resolving depression, promoting blood circulation by removing wind, improving eyesight, antipruritic.Dizzy for having a headache, distending pain in the chest and hypochondrium, breast closes acute mastitis, cataract, rubella pruritus, altogether for making medicine.
The each raw material of the present invention also can the embodiment that mixes of ratio (weight portion) listed by according to the form below realize, and its processing method is identical with embodiment one.
The clinical trial carried out below in conjunction with my institute is done further the present invention, is described in detail:
1, case selection: accept out-patient 100 example for medical treatment, give Drug therapy of the present invention, less than 40 years old 16 example, 40-49 year 39 examples, 50-59 year 28 examples, more than 60 years old 17 is routine.
2, Therapeutic Method:
Every day 1 dose point sooner or later 2 times oral, treat six months altogether.
3, diagnostic criteria:
All cases all determines diagnosis by goiter clinical manifestation diagnostic criteria.
4, efficacy evaluation: cure: clinical symptom disappearance, thyroid size is normal, within 3 months, has no recurrence.Effective: clinical symptom disappearance, Thyroid Tumors obviously reduces.Invalid: Thyroid Tumors has no significant change.
5, therapeutic effect: use this Chinese medicine to treat 100 examples altogether, cure 85 examples, effective 8 examples, invalid 7 examples, effective percentage is 93%, and inefficiency is 7%.
Model case:
Hu, man, 35 years old.Thyromegaly is more than 1 year, time have pharyngeal blocking to feel.Ultrasound diagnosis: bilateral thyroid is the even enlargement of moderate, about 5cm × 3cm × 2cm is inside shown in there is the strong echo of plaque-like, and matter is owed all, and isthmus is slightly shown in broadening.Diagnosis: bilateral thyromegaly.Take the present embodiment one side medicine one month, symptom obviously alleviates, and continues to take 2 months, and the disappearance of all diseases is fully recovered, and follows up a case by regular visits to and does not recur so far again.
Zhao, female, 26 years old.Occur acataposis, feel suffocated, be goiter after diagnosing, take the present embodiment one side medicine and fully recover after 2 months, drug withdrawal is not recurred so far.
Deng, man, 61 years old.Appearance is stridulated, and veins of upper extremity is congested, is goiter after diagnosing, takes the present embodiment one side medicine immediately and fully recover after 5 months, and drug withdrawal after continuing to take medicine 1 month, does not recur so far.

Claims (1)

1. one kind is used for the treatment of the Chinese medicine of thyromegaly, it is characterized in that being made up of the crude drug of following weight portion, Rhizoma Dioscoreae Bulbiferae 15 ~ 20, mouse muscle 10 ~ 15, Rhizoma seu Herba Elatostematis stewardii 8 ~ 12, Rhizoma Belamcandae 10 ~ 12, Radix Linderae Chunii 10 ~ 15, Herba abutili indici 6 ~ 10, cutter ash tree 20 ~ 25, Caulis Lonicerae 6 ~ 8, Radix Arnebiae (Radix Lithospermi) 10 ~ 12, Herba Veronicae Persicae 12 ~ 15, Flos Inulae 15 ~ 20, Fructus Citri 8 ~ 10, Fructus Toosendan 12 ~ 16, Herba Scutellariae Barbatae 6 ~ 10, Folium Pyrrosiae 15 ~ 20, Herba Pyrolae 16 ~ 18, Rhizoma Curculiginis 12 ~ 16, Herba Pothi Chinensis 3 ~ 5, Fructus Tribuli 3 ~ 5, above-mentioned 19 taste crude drug are soaked in water, to remove slag after decocting to obtain filtrate.
CN201410553305.5A 2014-10-09 2014-10-09 Traditional Chinese medicine for treating thyroid enlargement Pending CN104306635A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101049425A (en) * 2007-05-11 2007-10-10 张来祥 Precious medicines of dispersing accumulation of pathogen for treating breast-dripping wet
CN101152299A (en) * 2007-09-17 2008-04-02 尹克华 Traditional Chinese medicine for treating goiter and tumor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101049425A (en) * 2007-05-11 2007-10-10 张来祥 Precious medicines of dispersing accumulation of pathogen for treating breast-dripping wet
CN101152299A (en) * 2007-09-17 2008-04-02 尹克华 Traditional Chinese medicine for treating goiter and tumor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
高汉森等: "《甲亢中医疗法》", 30 September 2004 *

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