CN104306530A - Traditional Chinese medicine used for treating prolapse of lumbar intervertebral disc - Google Patents
Traditional Chinese medicine used for treating prolapse of lumbar intervertebral disc Download PDFInfo
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- CN104306530A CN104306530A CN201410479448.6A CN201410479448A CN104306530A CN 104306530 A CN104306530 A CN 104306530A CN 201410479448 A CN201410479448 A CN 201410479448A CN 104306530 A CN104306530 A CN 104306530A
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- 239000003814 drug Substances 0.000 title claims abstract description 25
- 208000012287 Prolapse Diseases 0.000 title claims abstract description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 7
- 241000903946 Clematidis Species 0.000 claims abstract description 5
- 241000173529 Aconitum napellus Species 0.000 abstract 1
- 241000382455 Angelica sinensis Species 0.000 abstract 1
- 241000758794 Asarum Species 0.000 abstract 1
- 241000123589 Dipsacus Species 0.000 abstract 1
- 241001116742 Drynaria Species 0.000 abstract 1
- 241001071795 Gentiana Species 0.000 abstract 1
- 244000018716 Impatiens biflora Species 0.000 abstract 1
- 235000015912 Impatiens biflora Nutrition 0.000 abstract 1
- 241000195954 Lycopodium clavatum Species 0.000 abstract 1
- 241000405911 Rehmannia glutinosa Species 0.000 abstract 1
- 235000017276 Salvia Nutrition 0.000 abstract 1
- 240000007164 Salvia officinalis Species 0.000 abstract 1
- 240000001638 Scurrula parasitica Species 0.000 abstract 1
- 235000005155 Tanacetum balsamita Nutrition 0.000 abstract 1
- 210000001015 abdomen Anatomy 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 5
- 208000002193 Pain Diseases 0.000 description 4
- 230000001737 promoting effect Effects 0.000 description 4
- 208000008035 Back Pain Diseases 0.000 description 3
- 208000008930 Low Back Pain Diseases 0.000 description 3
- 230000003203 everyday effect Effects 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 206010022562 Intermittent claudication Diseases 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 210000003414 extremity Anatomy 0.000 description 2
- 208000021156 intermittent vascular claudication Diseases 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 210000003141 lower extremity Anatomy 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 210000002435 tendon Anatomy 0.000 description 2
- 238000010792 warming Methods 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000005713 exacerbation Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 210000000278 spinal cord Anatomy 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
- A61K36/126—Drynaria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
- A61K36/268—Asarum (wild ginger)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/716—Clematis (leather flower)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Alternative & Traditional Medicine (AREA)
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- Medical Informatics (AREA)
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Abstract
The invention relates to a traditional Chinese medicine used for treating prolapse of the lumbar intervertebral disc. The traditional Chinese medicine is prepared by rehmannia glutinosa, dipsacus roots, drynaria rhizome, loranthus parasiticus, herba epimedii, radix clematidis, large-leaved gentian, radix stephaniae tetrandrae, garden balsam stems, lycopodium clavatum, radix aconiti preparata, prepared kusnezoff monkshood roots, asarum, angelica sinensis, roots of red-rooted salvia and caulis spatholobi. In the first dose, 700 milliliters of water is added into the traditional Chinese medicine to be decocted into 200 milliliters; in the second dose, 500 milliliters of water is added into the traditional Chinese medicine to be decocted into 200 milliliters; the traditional Chinese medicine is taken two times each day in the morning and at night with an empty belly.
Description
Technical field:
The present invention relates to a kind of Chinese medicine (belonging to technical field of Chinese medicines), particularly relate to a kind of Chinese medicine being used for the treatment of prolapse of lumbar intervertebral disc.
Background technology:
After prolapse of lumbar intervertebral disc refers to lumbar intervertebral disc generation degeneration, because certain reason (damage, overwork etc.) causes annulus fibrosus portion or all breaks, together with vertebral pulp in the lump outwards bulging, pressuring neural root or spinal cord cause the disease of lumbago and a series of nervous symptoms.Pain, particularly root pain are the cardinal symptom of prolapse of lumbar intervertebral disc, apply conventional orthopaedics analgesic often invalid, and for sharp ache or heavier early-stage cases, manipulation is difficult to tolerance more, and some even causes exacerbation of symptoms.
Summary of the invention:
The present invention is a kind of instant effect, good effect, Chinese medicine preparation without any side effects.
Medicine of the present invention is that raw material is prepared from by the Chinese medicine of following weight:
12 parts, Radix Rehmanniae Preparata, Radix Dipsaci 9 parts, Rhizoma Drynariae 12 parts, Herba Taxilli 9 parts, Herba Epimedii 12 parts, Radix Clematidis 9 parts, Radix Gentianae Macrophyllae 9 parts, Radix Stephaniae Tetrandrae 9 parts, Herba speranskiae tuberculatae 12 parts, Herba Lycopodii 12 parts, Radix Aconiti Preparata 6 parts, Radix Aconiti Kusnezoffii Preparata 6 parts, Herba Asari 3 parts, Radix Angelicae Sinensis 15 parts, Radix Salviae Miltiorrhizae 15 parts, Caulis Spatholobi 15 parts, every part are 1 gram.
Can any one made on pharmaceutics take said medicine orally dosage form, the preferred dosage form of the present invention is decoction.
The concrete preparation method of medicine of the present invention said medicine first dose is added water 700 milliliters to decoct to 200 milliliters, and second dose adds water 500 milliliters and decoct to 200 milliliters.
Using method is the decoction oral that will decoct, every day twice, sooner or later empty clothes.
The traditional Chinese medical science thinks that treatment prolapse of lumbar intervertebral disc should with liver and kidney tonifying, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, promoting the flow of QI in the collateral by warming the meridian for Therapeutic Principle.Radix Rehmanniae Preparata, Radix Dipsaci, Rhizoma Drynariae, Herba Taxilli, Herba Epimedii liver and kidney tonifying in side; Radix Clematidis, Radix Gentianae Macrophyllae, Radix Stephaniae Tetrandrae, Herba speranskiae tuberculatae expelling wind and removing dampness; Radix Angelicae Sinensis, Radix Salviae Miltiorrhizae, Caulis Spatholobi blood circulation promoting and blood stasis dispelling; Herba Lycopodii, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Herba Asari promoting the flow of QI in the collateral by warming the meridian.Said medicine compatibility uses, synergism, thus the object reaching treatment.
Curative effect of medication of the present invention is good, instant effect, taking convenience, have no side effect, and has good therapeutic effect to prolapse of lumbar intervertebral disc.
For proving clinical efficacy and the safety of invention medicine further, 63 routine patients are selected to observe medicine of the present invention.In 63 routine patients, within one month, be a course for the treatment of, one the course for the treatment of cured person 25 example, two the course for the treatment of cured person 15 example, two courses for the treatment of above cured person 21 example, invalid 2 examples, all use medicine of the present invention to treat, every day twice, sooner or later empty clothes.
Criterion of therapeutical effect: effective: lumbago, lower limb radiating pain or numb limbs and tense tendons and intermittent claudication symptom disappear; Effective: lumbago, lower limb radiating pain or numb limbs and tense tendons and intermittent claudication symptom are extenuated or disappear; Invalid: without significant change before and after treatment.
Rear statistical result treated by table 1
| Patient | Number of cases | Effective (%) | Effectively (%) | Invalid (%) | Total effective rate (%) |
| One the course for the treatment of cured person | 25 | 20(80) | 5(20) | 0(0) | 25(100) |
| Two the course for the treatment of cured person | 15 | 13(86.6) | 2(13.4) | 0(0) | 15(100) |
| Two the course for the treatment of above cured person | 23 | 6(26.1) | 15(65.2) | 2(8.7) | 21(91.3) |
| Amount to | 63 | 39(61.9) | 22(34.9) | 2(3.2) | 61(96.8) |
Detailed description of the invention:
12 parts, Radix Rehmanniae Preparata, Radix Dipsaci 9 parts, Rhizoma Drynariae 12 parts, Herba Taxilli 9 parts, Herba Epimedii 12 parts, Radix Clematidis 9 parts, Radix Gentianae Macrophyllae 9 parts, Radix Stephaniae Tetrandrae 9 parts, Herba speranskiae tuberculatae 12 parts, Herba Lycopodii 12 parts, Radix Aconiti Preparata 6 parts, Radix Aconiti Kusnezoffii Preparata 6 parts, Herba Asari 3 parts, Radix Angelicae Sinensis 15 parts, Radix Salviae Miltiorrhizae 15 parts, Caulis Spatholobi 15 parts, every part are 1 gram.
Decoct into decoction after said medicine being mixed, first dose adds water 700 milliliters and decocts to 200 milliliters, and second dose adds water 500 milliliters and decoct to 200 milliliters, every day twice, sooner or later empty clothes.
Claims (2)
1. being used for the treatment of a Chinese medicine for prolapse of lumbar intervertebral disc, is be made up of the medicine of following weight:
12 parts, Radix Rehmanniae Preparata, Radix Dipsaci 9 parts, Rhizoma Drynariae 12 parts, Herba Taxilli 9 parts, Herba Epimedii 12 parts, Radix Clematidis 9 parts, Radix Gentianae Macrophyllae 9 parts, Radix Stephaniae Tetrandrae 9 parts, Herba speranskiae tuberculatae 12 parts, Herba Lycopodii 12 parts, Radix Aconiti Preparata 6 parts, Radix Aconiti Kusnezoffii Preparata 6 parts, Herba Asari 3 parts, Radix Angelicae Sinensis 15 parts, Radix Salviae Miltiorrhizae 15 parts, Caulis Spatholobi 15 parts, every part are 1 gram.
2. a kind of Chinese medicine being used for the treatment of prolapse of lumbar intervertebral disc according to claim 1, is characterized in that described medicine with being decocted in water for oral dose into decoction oral.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410479448.6A CN104306530A (en) | 2014-09-09 | 2014-09-09 | Traditional Chinese medicine used for treating prolapse of lumbar intervertebral disc |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410479448.6A CN104306530A (en) | 2014-09-09 | 2014-09-09 | Traditional Chinese medicine used for treating prolapse of lumbar intervertebral disc |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104306530A true CN104306530A (en) | 2015-01-28 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410479448.6A Pending CN104306530A (en) | 2014-09-09 | 2014-09-09 | Traditional Chinese medicine used for treating prolapse of lumbar intervertebral disc |
Country Status (1)
| Country | Link |
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| CN (1) | CN104306530A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105943972A (en) * | 2016-06-27 | 2016-09-21 | 沙蕊 | Traditional Chinese medicine composition for treating low back pain after minimally invasive surgery of protrusion of lumbar intervertebral disc |
-
2014
- 2014-09-09 CN CN201410479448.6A patent/CN104306530A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105943972A (en) * | 2016-06-27 | 2016-09-21 | 沙蕊 | Traditional Chinese medicine composition for treating low back pain after minimally invasive surgery of protrusion of lumbar intervertebral disc |
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Application publication date: 20150128 |