CN104306152A - Three-cavity clamping type medicine bottle and injection device composite member thereof - Google Patents
Three-cavity clamping type medicine bottle and injection device composite member thereof Download PDFInfo
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- CN104306152A CN104306152A CN201410531322.9A CN201410531322A CN104306152A CN 104306152 A CN104306152 A CN 104306152A CN 201410531322 A CN201410531322 A CN 201410531322A CN 104306152 A CN104306152 A CN 104306152A
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Abstract
The invention relates to the field of medical apparatus and instruments and discloses a three-cavity clamping type medicine bottle and an injection device composite member thereof. The three-cavity clamping type medicine bottle comprises a bottle body, a front rubber plug, a front sealing cover, a rear piston and a rear sealing cover, wherein the front rubber plug and the front sealing cover are arranged on the front opening of the bottle body; the rear piston and the rear sealing cover are arranged in the rear opening of the bottle body; the bottle body is provided with a front cavity, a middle cavity and a rear cavity; the cross section of the front cavity is identical with the cross section of the rear cavity; the cross section shape of the middle cavity is respectively larger than the cross section shape of the front cavity and the cross section shape of the rear cavity; an isolation piston is arranged inside the rear cavity; an injection device comprises a push rod and a needle head, wherein the push rod is used for pushing the rear piston; the needle head is arranged on the front opening of the bottle body. According to the three-cavity clamping type medicine bottle and the injection device composite member thereof, the secondary pollution problem in the medicine preparation process and the injection process is systematically solved, the three-cavity clamping type medicine bottle and the injection device composite member thereof are not only suitable for urban hospitals and places with poor sanitary conditions, such as vast mountainous areas and countries, but also suitable for field, ships, battleground and disaster areas.
Description
Technical field
The present invention relates to medical instruments field, particularly a kind of three chamber cassette medical bottle and injection device molectrons thereof.
Background technology
As everyone knows, common medical bottle has ampoule bottle, cillin bottle, clamped bottle, precharging type syringe etc.
Ampoule bottle is the vial with flame sealing, be usually used in medicine and vaccine, the serum etc. of depositing injection, its cleaning, drying sterilizing and filling process maturation, sealing in fill adopts flame to heat the ampoule bottle cervical region of liquid drug, after it melts, by drawing seal technique, ampoule bottle is sealed.But because its sealing adopts flame heating, non-heat-resistant medicine can not be applicable to; On the other hand in potting process, exist and cause medicinal liquid chemical reaction due to high temperature thus affect the risk of drug quality.In use, need to cut bottleneck with emery wheel, free-handly to break into two with one's hands or ampoule bottle-neck opened by hard device, utilize the medicine in syringe pump ampoule bottle to inject, syringe directly contacts medicine.In formulation operations process as easy as rolling off a log cause sticking at bottle wall emery wheel end and chips of glass fall in medicine bottle, toxicity medicinal liquid and formulator's direct skin contact cause infection, ampoule bottle opening procedure herb liquid and contacting external air, there is secondary pollution problem, and its produce the dosage limited size of product.
Cillin bottle is gained the name because of the early stage penicillin of its splendid attire multiplex, and cillin bottle, also known as soda-lime glass injection bottle, is the ampoule of a kind of plug sealing.Have brown, the kind such as transparent, is generally glass material, and its neck part is comparatively thin, and the following thickness of bottleneck is consistent, and bottleneck is slightly coarser than bottleneck, is slightly narrower than body, can be used as iodine bottle, injection bottle, oral liquid bottle etc.When being used as injection bottle and using, similar with ampoule bottle, formulation operations process is loaded down with trivial details, need to utilize the medicine in syringe pump cillin bottle to inject, with in the pharmaceutical procedures in syringe pump cillin bottle, be difficult to sucking-off medicinal liquid owing to producing negative pressure in bottle, extracting force need be strengthened, allow medicinal liquid when producing negative pressure in needle tubing and stand upside down suck needle tubing, but extract to have instantaneously and can cause air intake needle tubing, there is secondary pollution problem.
Clamped bottle bottleneck is equipped with plug and seals with aluminium lid, and afterbody rubber piston seals, and is similar to the glass syringe of prepackage medicinal liquid, is separately furnished with injection bilateral guide pin syringe needle and push rod.Use procedure guide pin syringe needle penetrates bottleneck plug, and, medicinal liquid injects human body under the pressure of piston on the rubber piston that push rod is put in bottle afterbody firmly.Because clamped bottle back piston is not by aluminium lid wiper seal, medicinal liquid expands and very easily makes piston come off when high temperature sterilize, genus cannot carry out terminal sterilization product.Clamped bottle use procedure medicinal liquid is any component contact with syringe not, secondary pollution problem when solving injection.But because clamped bottle is nonterminal sterilising prods, its afterbody rubber piston seals, and can slide again during use, and the reliable process causing it to seal requires height, production cost is large, and production dosage form selection is limited to.
Precharging type syringe be by direct for injectable drug fill in glass syringe, and glass syringe is provided with injection needle, syringe and medicinal liquid packing container are united two into one, direct injection during use, very easy to use and the shelf-life is the same with ampulla and cillin bottle.It has following very outstanding advantage: without cross infection when (1) uses, in ward, unclean air does not reach medicine, accomplishes safety injection; (2) doctors and nurses is extremely easy to use, without the need to taking out medicine, without the need to installing syringe needle, and direct injection, single use; (3) medicine makes full use of, noresidue medicinal liquid; (4) remote locations is applicable to self-injection.But precharging type syringe is equally applicable to nonterminal sterilising prods, as biological activity vaccine etc., and its packaging material price is high, is difficult to promote.
For a large amount of medicine, accumulating in its Production and Packaging in pharmaceutical factory, sale and the occupation mode of hospital do not have significant change, especially pharmaceutical packing determines hospital's occupation mode, and relate to ubiquity secondary pollution of making up a prescription, there is no desirable solution at present, the slitless connection of drug manufacture, ingredients and injection human body can not be realized yet.
Summary of the invention
The object of the invention is to propose a kind of three chamber cassette medical bottle and injection device molectrons thereof, sealing reliability and the terminal sterilization of medical bottle can be ensured, direct injection human body after can directly making up a prescription in medical bottle, realize the slitless connection of drug manufacture and injection human body, secondary pollution problem when avoiding injecting
In order to achieve the above object, the present invention is achieved by the following technical solutions.
(1) three chamber cassette medical bottles, is characterized in that, comprise bottle, are arranged on the front plug of bottle front port, front capping, and are arranged on back piston, the rear seal-cover of bottle rear port; Described bottle has front cavity, middle cavity and rear chamber, the cross section of described front cavity is identical with the cross section of rear chamber, the cross sectional shape of middle cavity is greater than the cross sectional shape of front cavity and the cross sectional shape of rear chamber respectively, wherein be provided with separator piston in rear chamber, the length of described separator piston is less than the length of described middle cavity.
Feature and further improvement of technique scheme are:
Described front cavity is water preparation chamber, and middle cavity is ingredients chamber, and rear chamber is powder chamber.
Described front cavity is powder chamber, and middle cavity is ingredients chamber, and rear chamber is water preparation chamber.
The outer bottom of described back piston is provided with the Gask-O-Seal with its disjunctor.
The sidewall of described middle cavity is provided with axial groove.
(2) a kind of three chamber cassette medical bottle and injection device molectrons thereof, it is characterized in that, described three chamber cassette medical bottles, comprise bottle, be arranged on the front plug of bottle front port, front capping, and be arranged on back piston, the rear seal-cover of bottle rear port; Described bottle has front cavity, middle cavity and rear chamber, and the cross section of described front cavity is identical with the cross section of rear chamber, and the cross sectional shape of middle cavity is greater than the cross sectional shape of front cavity and the cross sectional shape of rear chamber respectively, is wherein provided with separator piston in rear chamber;
Described injection device comprises the push rod for pushing described back piston, and is arranged on the syringe needle of described bottle front port.
Feature and further improvement of technique scheme are:
The outer bottom of described back piston is provided with the blind hole be connected with described push rod.
The outer bottom of described back piston is provided with the Gask-O-Seal with its disjunctor, described push rod is set with the annular blade for back piston described in cutting and separating and Gask-O-Seal.
Described syringe needle is provided with the cutting ferrule with the connection of described bottle front port.
Described syringe needle is double needle, and described double needle comprises for the outer syringe needle of muscle puncture with for syringe needle in the described front plug that punctures, and the entrance of described interior syringe needle is arranged on sidewall.
Of the present invention have outstanding substantive distinguishing features and significant progress.
Wherein, three chamber cassette medical bottles comprise bottle, are arranged on the front plug of bottle front port, front capping, and are arranged on back piston, the rear seal-cover of bottle rear port; Such structure can realize terminal sterilization.
Wherein, bottle has front cavity, middle cavity and rear chamber, and the cross section of described front cavity is identical with the cross section of rear chamber, and the cross sectional shape of middle cavity is greater than the cross sectional shape of front cavity and the cross sectional shape of rear chamber respectively, is wherein provided with separator piston in rear chamber; Middle cavity is ingredients chamber, and front cavity and rear chamber are water preparation chamber or powder chamber.Such structure creates condition for realizing ingredients in bottle.
Wherein, injection device comprises the push rod for pushing described back piston, and is arranged on the syringe needle of described bottle front port.Injection device coordinates three chamber cassette medical bottles, can realize pigment preparation in bottle.
Present invention achieves 〝 sterilizing, namely join, directly note 〞 tri-functions, solve the world-famous puzzle in this medicine injection agent field.Thus thoroughly achieve: " from pharmaceutical production/GMP ~ medicine sales/GSP ~ to hospital's ingredients room water/whole industrial chain of powder preparation ~ human injection seamless/aseptic docking ", the track that injection medicine is run in whole industrial chain realizes: " totally-enclosed, aseptic greatly, seamless/aseptic docking " process.
This product is the medicine injection agent product of novel concept.Pharmaceuticals industry possess first " totally-enclosed, aseptic greatly, pollution-free, instant-matching type, direct-filling type, seamless (aseptic) docking " novel concept.It makes drug injection there occurs the property changed improvement.
It completes terminal sterilization (ingredients chamber) medicine in pharmaceutical factory, gnotobasis is not needed to make up a prescription during use, be can direct injection 〝 sterilizing, namely join, directly note the positive die pressing product of 〞/without negative pressure (needle tubing suction produces negative pressure), non-secondary pollution.Thorough solution and secondary pollution when having stopped drug injection (suction of traditional formulations process needle tubing produces negative pressure and sucks the pollution risk of air, plastics needle tubing/can not the risk of toxic residue of high temperature sterilize/chemosterilization) problem.
The present invention need not, by means of common needles, not need gnotobasis to make up a prescription, can directly in bottle pigment prepare and inject in human body, decrease secondary pollution problem of making up a prescription, achieve drug manufacture and injection human body slitless connection.
Accompanying drawing explanation
Below in conjunction with the drawings and specific embodiments, the present invention is described in further details.
Fig. 1 is the structural representation of a kind of three chamber cassette medical bottles of the present invention and injection device molectron thereof;
Fig. 2 (a), Fig. 2 (b), Fig. 2 (c), Fig. 2 (d) are respectively different middle chamber cross sectional shape schematic diagram;
Fig. 3 (a), Fig. 3 (b), Fig. 3 (c), Fig. 3 (d) are respectively the cooperation schematic diagram of different back piston and push rod;
Fig. 4 is the structural representation of syringe needle;
Fig. 5 is the using state schematic diagram of three chamber cassette medical bottles of the present invention and injection device molectron thereof.
In figure: 1, bottle; 2, front capping; 3, front plug; 4, back piston; 5, Gask-O-Seal; 6, rear seal-cover; 7, separator piston; 8, front chamber; 9, middle chamber; 10, rear chamber; 11, blind hole; 12, push rod; 13, annular blade; 14, syringe needle; 15, cutting ferrule; 16, the entrance of interior syringe needle.
Detailed description of the invention
With reference to Fig. 1, be a kind of three chamber cassette medical bottle and injection device molectrons thereof of the present invention.
Wherein, three chamber cassette medical bottles, comprise bottle 1, are arranged on the front plug 3 of bottle 1 front port, front capping 2, and are arranged on back piston 4, the rear seal-cover 6 of bottle 1 rear port.
Bottle 1 has front cavity 8, middle cavity 9 and rear chamber 10, the cross section of front cavity 8 is identical with the cross section of rear chamber 10, the cross sectional shape of middle cavity 9 is greater than the cross sectional shape of front cavity 8 and the cross sectional shape of rear chamber 10 respectively, wherein be provided with separator piston 7 in rear chamber, and require that the length of separator piston 7 is less than the length of middle cavity.Like this, middle cavity 9 is ingredients chamber, and front cavity 8 and rear chamber 10 are respectively water preparation chamber or powder chamber.Middle cavity 9 is as ingredients chamber, and object is separator piston 7 when being arranged in cavity 9, can make to be communicated with front cavity 8 and rear chamber 10, to reach the abundant mixing of water preparation and powder.
In order to better achieve the above object, the present embodiment, for the cross sectional shape of middle cavity 9, gives usual form as Fig. 2 (a); And preferred form is as Fig. 2 (b), Fig. 2 (c), Fig. 2 (d), wherein the sidewall of cavity is respectively arranged with the well-mixed axial groove that, two, three promote water preparation and powder.
Wherein, injection device comprises the push rod 12 for pushing back piston 4, and is arranged on the syringe needle 14 of bottle 1 front port.
Back piston 4 specifically contacts connected mode with push rod 12 to be had multiple, as shown in Fig. 3 (a), 3 (b), Fig. 3 (c), Fig. 3 (d); Wherein, preferred embodiment is as shown in Fig. 3 (a), and the outer bottom of back piston 4 is provided with the blind hole 11 be connected with push rod 12; Or as shown in Fig. 3 (b), the outer bottom of back piston 4 is provided with the Gask-O-Seal 5 with its disjunctor, push rod 12 is set with the annular blade 13 for cutting and separating back piston 4 and Gask-O-Seal 5.
Syringe needle 14 is double needle, syringe needle 14 is provided with the cutting ferrule 15 with the connection of bottle front port.Wherein, double needle comprises for the outer syringe needle of muscle puncture with for syringe needle in the described front plug that punctures, and the entrance 16 of interior syringe needle is arranged on sidewall, as shown in Figure 4
With reference to Fig. 4, use procedure of the present invention is described.In drug packaging process, front cavity 8 is powder chamber, and middle cavity 9 is ingredients chamber, and rear chamber 10 is water preparation chamber.Also can front cavity 8 be water preparation chamber, middle cavity 9 is ingredients chamber, rear chamber is 10 powder chambeies, at this moment it should be noted that the useful load of water preparation needs to limit, during to ensure pushing separator piston 7, the gas compression volume of front cavity 8 and middle cavity 9 is not less than the own vol of separator piston 7, so that separator piston 7 can be pushed in middle cavity 9.
During use, utilize push rod 12 directly to promote back piston 4, now separator piston 7 is also promoted indirectly, until when separator piston 7 can be pressed in middle cavity 9, front cavity 8, middle cavity 9, rear chamber 10 are communicated with, and water preparation and powder mixing; Promote back piston 4 and separator piston 7 more simultaneously, can intramuscular injection be completed.
Technique scheme of the present invention, successfully solve the secondary pollution problem of the process of making up a prescription and injection process, be not only applicable to policlinic, be also applicable to the place of the sanitary condition differences such as extensive mountain area, rural area, field, naval vessel and battlefield, disaster area can also be applicable to.
Although be below described embodiment of the present invention by reference to the accompanying drawings, the present invention is not limited to above-mentioned specific embodiments, and above-mentioned specific embodiments is only schematic, guiding, instead of restrictive.Those of ordinary skill in the art is under the enlightenment of this description, and when not departing from the scope that the claims in the present invention are protected, can also make a variety of forms, these all belong to the row of the present invention's protection.
Claims (10)
1. three chamber cassette medical bottles, is characterized in that, comprise bottle, are arranged on the front plug of bottle front port, front capping, and are arranged on back piston, the rear seal-cover of bottle rear port; Described bottle has front cavity, middle cavity and rear chamber, and the cross section of described front cavity is identical with the cross section of rear chamber, and the cross sectional shape of middle cavity is greater than the cross sectional shape of front cavity and the cross sectional shape of rear chamber respectively, is wherein provided with separator piston in rear chamber.
2. three chamber cassette medical bottles according to claim 1, it is characterized in that, described front cavity is water preparation chamber, and middle cavity is ingredients chamber, and rear chamber is powder chamber.
3. three chamber cassette medical bottles according to claim 1, it is characterized in that, described front cavity is powder chamber, and middle cavity is ingredients chamber, and rear chamber is water preparation chamber.
4. three chamber cassette medical bottles according to claim 1, is characterized in that, the outer bottom of described back piston is provided with the Gask-O-Seal with its disjunctor.
5. three chamber cassette medical bottles according to claim 1, it is characterized in that, the sidewall of described middle cavity is provided with axial groove.
6. three chamber cassette medical bottle and injection device molectrons thereof, is characterized in that,
Described three chamber cassette medical bottles, comprise bottle, are arranged on the front plug of bottle front port, front capping, and be arranged on back piston, the rear seal-cover of bottle rear port; Described bottle has front cavity, middle cavity and rear chamber, and the cross section of described front cavity is identical with the cross section of rear chamber, and the cross sectional shape of middle cavity is greater than the cross sectional shape of front cavity and the cross sectional shape of rear chamber respectively, is wherein provided with separator piston in rear chamber;
Described injection device comprises the push rod for pushing described back piston, and is arranged on the syringe needle of described bottle front port.
7. three chamber cassette medical bottle and injection device molectrons thereof according to claim 6, is characterized in that, the outer bottom of described back piston is provided with the blind hole be connected with described push rod.
8. three chamber cassette medical bottle and injection device molectrons thereof according to claim 6, it is characterized in that, the outer bottom of described back piston is provided with the Gask-O-Seal with its disjunctor, described push rod is set with the annular blade for piston described in cutting and separating and Gask-O-Seal.
9. three chamber cassette medical bottle and injection device molectrons thereof according to claim 6, is characterized in that, described syringe needle are provided with the cutting ferrule with the connection of described bottle front port.
10. three chamber cassette medical bottle and injection device molectrons thereof according to claim 6, it is characterized in that, described syringe needle is double needle, and described double needle comprises for the outer syringe needle of muscle puncture with for syringe needle in the described front plug that punctures, and the entrance of described interior syringe needle is arranged on sidewall.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410531322.9A CN104306152A (en) | 2014-10-10 | 2014-10-10 | Three-cavity clamping type medicine bottle and injection device composite member thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410531322.9A CN104306152A (en) | 2014-10-10 | 2014-10-10 | Three-cavity clamping type medicine bottle and injection device composite member thereof |
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| CN104306152A true CN104306152A (en) | 2015-01-28 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410531322.9A Pending CN104306152A (en) | 2014-10-10 | 2014-10-10 | Three-cavity clamping type medicine bottle and injection device composite member thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109328109A (en) * | 2017-01-03 | 2019-02-12 | 伊鲁米那股份有限公司 | Sample tube with integral type mixing stopper head |
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|---|---|---|---|---|
| CN1225574A (en) * | 1996-06-04 | 1999-08-11 | Delab公司 | Method for preparing injectable prepn.and device for implementing same |
| CN101090745A (en) * | 2004-10-25 | 2007-12-19 | 制药咨询有限及两合继承公司 | Method and devices for lyophilizing, reconstituting, and administering a reconstituted agent |
| CN101811605A (en) * | 2010-02-25 | 2010-08-25 | 丁国成 | Syringe type quantitative packaging system |
| CN103505366A (en) * | 2013-10-10 | 2014-01-15 | 丁一玲 | Back pressure type medical bottle and composite element of dispensing device and injection device thereof |
| CN203436632U (en) * | 2013-08-08 | 2014-02-19 | 丁一玲 | Assembling unit of injection device and seeding bottles |
-
2014
- 2014-10-10 CN CN201410531322.9A patent/CN104306152A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1225574A (en) * | 1996-06-04 | 1999-08-11 | Delab公司 | Method for preparing injectable prepn.and device for implementing same |
| CN101090745A (en) * | 2004-10-25 | 2007-12-19 | 制药咨询有限及两合继承公司 | Method and devices for lyophilizing, reconstituting, and administering a reconstituted agent |
| CN101811605A (en) * | 2010-02-25 | 2010-08-25 | 丁国成 | Syringe type quantitative packaging system |
| CN203436632U (en) * | 2013-08-08 | 2014-02-19 | 丁一玲 | Assembling unit of injection device and seeding bottles |
| CN103505366A (en) * | 2013-10-10 | 2014-01-15 | 丁一玲 | Back pressure type medical bottle and composite element of dispensing device and injection device thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109328109A (en) * | 2017-01-03 | 2019-02-12 | 伊鲁米那股份有限公司 | Sample tube with integral type mixing stopper head |
| JP2020504000A (en) * | 2017-01-03 | 2020-02-06 | イラミーナ インコーポレーテッド | Sample tube with integrated mixing plunger head |
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Application publication date: 20150128 |
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