CN104306082B - Respiratory tract hot injury animal imitating experimental provision - Google Patents

Respiratory tract hot injury animal imitating experimental provision Download PDF

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Publication number
CN104306082B
CN104306082B CN201410652093.6A CN201410652093A CN104306082B CN 104306082 B CN104306082 B CN 104306082B CN 201410652093 A CN201410652093 A CN 201410652093A CN 104306082 B CN104306082 B CN 104306082B
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air
cabin
hot
valve
laboratory animal
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CN104306082A (en
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范维林
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Tianjin Hope Industry and Trade Co Ltd
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Tianjin Hope Industry and Trade Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61DVETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A61D7/04Devices for anaesthetising animals by gases or vapours; Inhaling devices

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
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  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Housing For Livestock And Birds (AREA)

Abstract

The invention provides a kind of respiratory tract hot injury animal imitating experimental provision, it is characterized in that: comprise one produce heated dry air or damp-heat air and driving pressure preheat cabin, preheat top, cabin and be connected to cabin Pressure gauge, cabin thermometer and cabin humidometer are to observe and to control the hot-air parameter that preheats in cabin, under pressure-driven, hot-air is transported to rapidly in respiratory airway by steam on-off valve and carries out respiratory tract hot injury simulation experiment on fixing stature by the be tightly connected laboratory animal of nasal mask of fixing headband, the air inlet mouth of pipe of respiratory airway and the mouth of pipe of giving vent to anger can maintain laboratory animal and breathe normally, the airway pressure gauge connected above respiratory airway, airway temperature table and air flue humidometer, real-time display laboratory animal is exhaled and hot-air parameter in cycle of air-breathing and respiratory airway.The invention has the beneficial effects as follows: this device can complete safely, accurately, easily and meet scientific xeothermic factor or damp and hot factor causes imbedibility hot injury simulation experiment.

Description

Respiratory tract hot injury animal imitating experimental provision
Technical field
The present invention relates to a kind of respiratory tract hot injury animal imitating experimental provision.
Background technology
Xeothermic factor and damp and hot factor cause respiratory system hot injury disease to be very general and that harm is serious problem.In Medical research, the respiratory system disease larger to mankind's hazardness will be prevented in advance, therefore the research of the aspects such as corresponding treatment and related pathologies pharmacology will be carried out, past major part experiment uses xeothermic and damp and hot scene and carries out, but because device structure more complicated method is clumsy again, so complicated operation is not easy to control, equipment runs the resource that needs and cost is higher is unfavorable for wide popularization and application, the requirement of the environmental simulation experiment of current scientific experiment in enormous quantities and more and more refinement can not be adapted to, have impact on the progress of this field scientific research to a certain extent, hinder the deep development of correlational study, in order to overcome above-mentioned difficulties, fundamentally solve above-mentioned Problems existing in research work, meet scientific research and carry out easy in testing in enormous quantities, fast, the needs of low cost standard test, research and develop and a kind ofly do not re-use traditional complex structure, method is clumsy, experimental provision costly has just become inevitable and exigence to the respiratory tract hot injury animal imitating experimental provision of field experimentation.
Summary of the invention
For solving the problem, the object of this invention is to provide a kind of respiratory tract hot injury animal imitating experimental provision, produce heated dry air or damp-heat air and driving pressure, under pressure-driven, heated dry air or damp-heat air are transported in respiratory airway rapidly by steam on-off valve and test to laboratory animal, can complete safely, accurately, easily and meet the simulation experiment that scientific xeothermic factor or damp and hot factor cause imbedibility hot injury.
For achieving the above object, technical scheme of the present invention is to provide a kind of respiratory tract hot injury animal imitating experimental provision, comprise one by high-temperature electric heat device, hot-water nozzle and add that air pipe produces hot-air and driving pressure preheat cabin, have three passages above cabin and respectively connected cabin Pressure gauge preheating, cabin thermometer and cabin humidometer, the control gas parameter preheated in cabin, cabin can be observed at any time and comprise pressure, temperature and humidity, namely preheat cabin can provide heated dry air to carry out breathing the experiment of xeothermic lesion mimic to respiratory airway, also vapours can be formed by spraying hot water on high-temperature heating sheet, reaching temperature required provides damp-heat air to carry out breathing the experiment of damp and hot lesion mimic with when pressure to respiratory airway, under controlling the control of the steam on-off valve of opening at any time or closing with manual pressure handle ball at one, by pressure-driven, heated dry air or damp-heat air are transported to rapidly the test also simultaneously carrying out simulated respiration road hot injury in respiratory airway to the laboratory animal be fixed on after nasal mask, laboratory animal is fixedly placed on a special fixing stature motionless with fixing body belt restraining, laboratory animal head has fixing headband to be connected by the face seal of nasal mask and laboratory animal not reveal gas, loudspeaker osculum one end of nasal mask and respiratory airway are tightly connected, remain normal by the air inlet mouth of pipe and the mouth of pipe of giving vent to anger time usual to breathe, the top of respiratory airway has three passages and respectively connected airway pressure gauge, airway temperature table and air flue humidometer, can show and understand laboratory animal in real time according to manometric height and change-over period to exhale and gas parameter in cycle of air-breathing and respiratory airway, can safety, accurately, complete easily and meet scientific xeothermic factor or damp and hot factor imbedibility hot injury simulation experiment.
The invention has the beneficial effects as follows: develop and a kind ofly do not re-use traditional complex structure, method is clumsy, experimental provision is costly to the respiratory tract hot injury animal imitating experimental provision of field experimentation, heated dry air or damp-heat air can be provided to carry out breathing the experiment of xeothermic lesion mimic, real-time display and understand laboratory animal and exhale and gas parameter in cycle of air-breathing and respiratory airway, can complete the xeothermic factor or damp and hot factor imbedibility hot injury simulation experiment that meet science safely, accurately, easily.
Accompanying drawing explanation
Accompanying drawing is the schematic diagram of structure of the present invention.
In figure:
1, pressure handle ball 2, valve body 3, O-ring seal 4, airway pressure gauge 5, airway temperature table 6, air flue humidometer
7, respiratory airway 8, fixing headband 9, fixing body band 10 laboratory animal 11, fixing stature 12, mask seal circle
13, nasal mask 14, piston seal mouth 15, the air inlet mouth of pipe 16, air-breathing one-way piston 17, the mouth of pipe of giving vent to anger
18, damping spring 19, expiration one-way piston 20, steam on-off valve 21, back-moving spring 22, outer valve circle
23, steam outlet tube 24, high-temperature electric heat device 25, high-temperature heating sheet 26, preheat cabin 27, temperature control electrical heating core
28, hot water 29, water heater 30, compressed gas source 31, thermal insulation layer 32, cabin Pressure gauge
33, cabin thermometer 34, cabin humidometer 35, hot water valve 36, High-pressure air valve 37, hot-water nozzle
38, air pipe 39, valve rod 40, hollow valve port is added.
Detailed description of the invention
By reference to the accompanying drawings and embodiment the present invention is illustrated.
As shown in drawings, the invention provides a kind of respiratory tract hot injury animal imitating experimental provision, comprise one by high-temperature electric heat device 24, hot-water nozzle 37 and add that air pipe 38 produces hot-air and driving pressure preheat cabin 26, preheating cabin 26 is seal hatchs that there is thermal insulation layer 31 outside made by insulation high-temperature-resistant material, the below of its inside is provided with high-temperature electric heat device 24 and heats to high-temperature heating sheet 25, above sealed compartment, have three passages respectively connected cabin Pressure gauge 32, cabin thermometer 33 and cabin humidometer 34, the control gas parameter preheated in cabin, cabin 26 can be observed at any time and comprise pressure, temperature and humidity, cabin internal upper part is provided with and adds air pipe 38 and be communicated to High-pressure air valve 36 and compressed gas source 30 by preheating cabin 26 sidewall, in cabin, bottom is provided with hot-water nozzle 37 and is communicated to hot water valve 35 and water heater 29 by preheating cabin 26 sidewall by sealing pipeline, water heater 29 is also communicated with compressed gas source 30, water heater 29 is the sealing hot water tanks made by the high pressure resistant sturdy material of high-temperature insulation, container bottom has temperature control electrical heating core 27 to feed water at any time Automatic-heating, be heated to uniform temperature automatically to stop ensureing that water temperature within the specific limits, water heater 29 top has an aperture and is connected to compressed gas source 30 by sealing pipeline, water heater 29 inside sealed can be kept to have certain pressure, water heater 29 is positioned at horizontal plane and has an aperture below, hot-water nozzle 37 is communicated to by sealing pipeline and hot water valve 35, when hot water valve 35 is opened, hot water 28 is sprayed water to the high-temperature heating sheet 25 preheated in cabin 26 by hot-water nozzle 37 under pressure-driven, form vapours for experimental applications, in cabin, middle part is provided with steam outlet tube 23 and is communicated to steam on-off valve 20 by preheating cabin 26 sidewall, namely preheat cabin 26 can provide heated dry air to carry out breathing the experiment of xeothermic lesion mimic to respiratory airway 7, also vapours can be formed by spraying hot water 28 on high-temperature heating sheet, reaching temperature required provides damp-heat air to carry out breathing the experiment of damp and hot lesion mimic with when pressure to respiratory airway 7, respiratory airway 7 is the straight-through pipelines exported by multiple difference made by insulation high-temperature-resistant material, the radial hole of its one end and steam on-off valve 20 is tightly connected, the other end is directly connected to nasal mask 13 can supply breathing gas or hot-air to laboratory animal 10, the below of respiratory airway 7 has two passages and respectively connected the air inlet mouth of pipe 15 and the mouth of pipe 17 of giving vent to anger, give the air that laboratory animal 10 provides eupnea used at any time, steam on-off valve 20 is the valve bodies 2 with the manual sealing of steam on-off function made by insulation high-temperature-resistant material, its outside has outer valve circle 22 to be an open column shape structure, an overall through thicker axial hole in the middle of valve circle 22 axle center outside, axial hole inner wall smooth closely cooperates installation valve rod 39, axial hole upper inside wall have an O-ring seal 3 closely cooperate valve rod 39 ensure sealing air tight, valve circle 22 waist intermediate lateral has the radial hole that vertically runs through axial hole outside, radial hole is while be communicated to by steam outlet tube 23 and preheat in cabin 26, radial hole another side is communicated to the nasal mask 13 of laboratory animal 10 by respiratory airway 7, valve rod 39 smooth outer surface is trapped among in outer valve circle 22 by sealed packet, valve rod 39 is provided with back-moving spring 21 below and keeps valve rod 39 to be usually positioned at by the state of jack-up, valve rod 39 intermediate lateral have one with the hollow valve port 40 of the isodiametric circle of steam outlet tube 23, hollow valve port 40 when valve rod 39 is positioned at the position by jack-up usually on valve rod 39 misplaces with the radial hole of outer valve circle 22 waist intermediate lateral, valve rod 39 is blocked in and plays insulating effect in the middle of radial hole and make steam obstructed, when pressing the pressure handle ball 1 being positioned at valve rod 39 top, valve rod 39 is moved down into the radial hole position consistency that bottom makes hollow valve port on valve rod 39 40 and outer valve circle 22 waist intermediate lateral, being communicated with steam on-off valve 20 makes steam circulate, under controlling the control of the steam on-off valve 20 of opening at any time or closing with manual pressure handle ball 1 at one, by pressure-driven, heated dry air or damp-heat air are transported to rapidly the test also simultaneously carrying out simulated respiration road hot injury in respiratory airway 7 to the laboratory animal 10 be fixed on after nasal mask 13, nasal mask 13 is the vent hoods of the bell mouth shape made by high-temperature flexible insulant, its shape experimentally animal 10 face shape and designing, its loudspeaker osculum one end is a ventilation connector be tightly connected with respiratory airway 7, its loudspeaker great Kou one end is the soft limit of circle conformed to laboratory animal 10 face shape, the soft limit of circle has mask seal circle 12 to ensure, and nasal mask 13 is connected with the nasal seal of laboratory animal 10, on the soft limit of circle, nasal mask 13 is fixedly secured the head in laboratory animal 10 by fixing headband 8 in addition, laboratory animal 10 is fixedly placed in and a special fixing stature 11 retrains motionless with fixing body band 9, laboratory animal 10 head has fixing headband 8 to be connected by the face seal of nasal mask 13 and laboratory animal 10 not reveal gas, loudspeaker osculum one end and the respiratory airway 7 of nasal mask 13 are tightly connected, normal breathing is maintained by the air inlet mouth of pipe 15 and the mouth of pipe 17 of giving vent to anger time usual, the air inlet mouth of pipe 15 is the air-valve devices controlling one-way air inlet, the sealing of its one end is fixed on the tube wall of respiratory airway 7, near the inside of respiratory airway 7 one end, the air-breathing one-way piston 16 with damping spring 18 is installed, when presenting normal pressure in respiratory airway 7 in usual situation, damping spring 18 push-tight air-breathing from inside to outside one-way piston 16 and piston seal mouth 14 close contact, keep gas circuit sealing state of isolation, also be like this when laboratory animal 10 is exhaled or steam connects in experimentation, under reverse situation, negative pressure state is rendered as in respiratory airway 7 when laboratory animal 10 air-breathing, damping spring 18 is disengaged with piston seal mouth 14 by gas negative pressure compression air-breathing one-way piston 16, gas circuit is kept to open air-suction state, outside air provides ozone to supply laboratory animal 10 eupnea to respiratory airway 7, the mouth of pipe 17 of giving vent to anger also is a control unidirectional air-valve device of giving vent to anger contrary with the air inlet mouth of pipe 15 direction, the sealing of its one end is fixed on the tube wall of respiratory airway 7, near the inside of respiratory airway 7 one sections, piston seal mouth 14 is installed, in usual situation, respiratory airway 7 is interior without pressure or when presenting negative pressure, with expiration one-way piston 19 ecto-entad push-tight and piston seal mouth 14 close contact of damping spring 18, keep gas circuit sealing state of isolation, under reverse situation, barotropic state is rendered as in respiratory airway 7 when laboratory animal 10 expired gas, damping spring 18 is compressed by gas positive pressure, expiration one-way piston 19 and piston seal mouth 14 disengage, gas circuit is kept to open exhaust condition, ensure that laboratory animal 7 breath is got rid of in time, also be like this when laboratory animal 10 is exhaled or steam connects in experimentation, the top of respiratory airway 7 has three passages and respectively connected airway pressure gauge 4, airway temperature table 5 and air flue humidometer 6, can show and understand laboratory animal 10 in real time according to manometric height and change-over period to exhale and gas parameter in cycle of air-breathing and respiratory airway 7, the xeothermic factor or damp and hot factor imbedibility hot injury simulation experiment that meet science can be completed safely, accurately, easily.
Embodiment:
First water heater 29 li is loaded hot water 28 before using, then the temperature control electrical heating core 27 of the container bottom of water heater 29 feeds water Automatic-heating at any time, is heated to uniform temperature and automatically stops ensureing that water temperature within the specific limits, the high-temperature electric heat device 24 preheating the below of inside, cabin 26 heats to high-temperature heating sheet 25, ensures that valve rod 39 is positioned at by the position of jack-up, and the hollow valve port 40 now on valve rod 39 misplaces with the radial hole of outer valve circle 22 waist intermediate lateral, get out laboratory animal, select suitable nasal mask 13, its shape is the face shape of experimentally animal 10 and designs, its loudspeaker osculum one end is a ventilation connector be tightly connected with respiratory airway 7, its loudspeaker great Kou one end is the soft limit of circle conformed to laboratory animal 10 face shape, the soft limit of circle has mask seal circle 12 to ensure, and nasal mask 13 is connected with the nasal seal of laboratory animal 10, and on the soft limit of circle, nasal mask 13 is fixedly secured the head in laboratory animal 10 by fixing headband 8 in addition, again laboratory animal 10 is fixedly placed in and a special fixing stature 11 retrains motionless with fixing body band 9, two passages had in the below of respiratory airway 7 respectively connected the air inlet mouth of pipe 15 and the mouth of pipe 17 of giving vent to anger, the air providing eupnea used at any time laboratory animal 10, ensures laboratory animal eupnea, when needs do xeothermic injury experiment, open High-pressure air valve 36, the heated dry air that compressed gas source 30 produces and driving pressure enter preheat cabin 26 by adding air pipe 38, and heated dry air is for the xeothermic lesion mimic experimental applications of respiratory tract, when needs do damp and hot injury experiment, open hot water valve 35 simultaneously, water heater 29 is positioned at horizontal plane an aperture below, hot-water nozzle 37 is communicated to by sealing pipeline and hot water valve 35, at this moment hot water 28 is sprayed water to the high-temperature heating sheet 25 preheated in cabin 26 by hot-water nozzle 37 under pressure-driven, and reaching temperature required provides damp-heat air to carry out breathing the experiment of damp and hot lesion mimic with when pressure to respiratory airway 7, the top preheating cabin 26 has three passages and respectively connected cabin Pressure gauge 32, cabin thermometer 33 and cabin humidometer 34, can observe the control gas parameter preheated in cabin, cabin 26 at any time and comprise pressure, temperature and humidity, under the control of the steam on-off valve 20 controlling to open at any time or close with manual pressure handle ball 1, by pressure-driven, heated dry air or damp-heat air are transported to rapidly the test carrying out simulated respiration road hot injury in respiratory airway 7 to the laboratory animal 10 be fixed on after nasal mask 13, when pressing the pressure handle ball 1 of valve rod 39 top being positioned at steam on-off valve 20, valve rod 39 is moved down into the radial hole position consistency that bottom makes hollow valve port on valve rod 39 40 and outer valve circle 22 waist intermediate lateral, be communicated with steam on-off valve 20 and make to preheat heated dry air in cabin, cabin 26 or damp-heat air is passed to respiratory airway 7 by the steam outlet tube 23 preheating cabin 26 sidewall under pressure-driven, the radial hole of its one end and steam on-off valve 20 is tightly connected, the other end is directly connected to nasal mask 13 can supply breathing gas or hot-air to laboratory animal 10, the below of respiratory airway 7 has two passages and respectively connected the air inlet mouth of pipe 15 and the mouth of pipe 17 of giving vent to anger, give the air that laboratory animal 10 provides eupnea used at any time, the air inlet mouth of pipe 15 is provided with the air-breathing one-way piston 16 with damping spring 18 near the inside of respiratory airway 7 one end, when presenting normal pressure in respiratory airway 7 in usual situation, damping spring 18 push-tight air-breathing from inside to outside one-way piston 16 and piston seal mouth 14 close contact, keep gas circuit sealing state of isolation, also be like this when laboratory animal 10 is exhaled or steam connects in experimentation, under reverse situation, negative pressure state is rendered as in respiratory airway 7 when laboratory animal 10 air-breathing, damping spring 18 is disengaged with piston seal mouth 14 by gas negative pressure compression air-breathing one-way piston 16, gas circuit is kept to open air-suction state, outside air provides ozone to supply laboratory animal 10 eupnea to respiratory airway 7, the mouth of pipe 17 of giving vent to anger is control unidirectional air-valve devices of giving vent to anger contrary with the air inlet mouth of pipe 15 direction, along with the expiration one-way piston 19 of damping spring 18 with the close contact of piston seal mouth 14 or disengage, keep gas circuit sealing state of isolation or gas circuit to open exhaust condition, ensure that the expiration of laboratory animal 10 in experimentation or steam are connected, the top of respiratory airway 7 has three passages and respectively connected airway pressure gauge 4, airway temperature table 5 and air flue humidometer 6, can show and understand laboratory animal 10 in real time according to manometric height and change-over period to exhale and gas parameter in cycle of air-breathing and respiratory airway 7, safety, complete the xeothermic factor that meets science or damp and hot factor imbedibility hot injury simulation experiment accurately, easily.After having tested, the pressure handle ball 1 of pull-up valve rod 39 top makes it reset, hollow valve port 40 on valve rod 39 misplaces with the radial hole of outer valve circle 22 waist intermediate lateral, valve rod 39 is blocked in and plays insulating effect in the middle of radial hole and make heated dry air or damp-heat air can not lead to respiratory airway 7, cut off water heater 29, compressed gas source 30, the power supply of high-temperature electric heat device, close High-pressure air valve 36 and hot water valve 35, untie the fixing body band 9 of laboratory animal 10, laboratory animal 10 is taken off from special fixing stature 11, untie the fixing headband 8 in nasal mask 13, the head of nasal mask 13 from laboratory animal 10 is taken, clean up nasal mask 13 in order to reusing from now on, the scientific research doing next step through the laboratory animal 10 of respiratory tract hot injury animal imitating experiment is analyzed and is used.

Claims (8)

1. a respiratory tract hot injury animal imitating experimental provision, it is characterized in that: comprise one by high-temperature electric heat device (24), hot-water nozzle (37) and add that air pipe (38) produces hot-air and driving pressure preheat cabin (26), have three passages in the top preheating cabin (26) and respectively connected cabin Pressure gauge (32), cabin thermometer (33) and cabin humidometer (34), the gas parameter that control preheats in cabin (26) cabin can be observed at any time and comprise pressure, temperature and humidity, preheat cabin (26) interior bottom hot-water nozzle (37) is installed is communicated to hot water valve (35) and water heater (29) by preheating cabin (26) sidewall by sealing pipeline, preheating cabin (26) can either provide heated dry air to carry out breathing the experiment of xeothermic lesion mimic to respiratory airway (7), also vapours can be formed by spraying hot water (28) on high-temperature heating sheet, reaching temperature required provides damp-heat air to carry out breathing the experiment of damp and hot lesion mimic with when pressure to respiratory airway (7), under the control of a steam on-off valve (20) of opening at any time with the control of manual pressure handle ball (1) or closing, by pressure-driven, heated dry air or damp-heat air are transported to rapidly the test also simultaneously carrying out simulated respiration road hot injury in respiratory airway (7) to the laboratory animal (10) be fixed on after nasal mask (13), laboratory animal (10) is fixedly placed in that a special fixing stature (11) is upper to be retrained motionless with fixing body band (9), laboratory animal (10) head has fixing headband (8) to be connected by the face seal of nasal mask (13) and laboratory animal (10) not reveal gas, loudspeaker osculum one end and the respiratory airway (7) of nasal mask (13) are tightly connected, maintained by the air inlet mouth of pipe (15) and the mouth of pipe of giving vent to anger (17) time usual and breathe normally, the top of respiratory airway (7) has three passages and respectively connected airway pressure gauge (4), airway temperature table (5) and air flue humidometer (6), can show and understand laboratory animal (10) in real time according to manometric height and change-over period to exhale and gas parameter in cycle of air-breathing and respiratory airway (7), can safety, accurately, complete easily and meet scientific xeothermic factor or damp and hot factor imbedibility hot injury simulation experiment.
2. a kind of respiratory tract hot injury animal imitating experimental provision according to claim 1, it is characterized in that: described in preheat cabin (26) be the seal hatch that there are thermal insulation layer (31) outside made by insulation high-temperature-resistant material, the below of its inside is provided with high-temperature electric heat device (24) and heats to high-temperature heating sheet (25), above sealed compartment, have three passages respectively connected cabin Pressure gauge (32), cabin thermometer (33) and cabin humidometer (34), the gas parameter of control cabinet indoor can be observed at any time, cabin internal upper part is provided with and adds air pipe (38) and be communicated to High-pressure air valve (36) and compressed gas source (30) by preheating cabin (26) sidewall, in cabin, bottom is provided with hot-water nozzle (37) and is communicated to hot water valve (35) and water heater (29) by preheating cabin (26) sidewall by sealing pipeline, water heater (29) is also communicated with compressed gas source (30), in cabin, middle part is provided with steam outlet tube (23) and is communicated to steam on-off valve (20) by preheating cabin (26) sidewall.
3. a kind of respiratory tract hot injury animal imitating experimental provision according to claim 1, it is characterized in that: described steam on-off valve (20) is the valve body (2) with the manual sealing of steam on-off function made by insulation high-temperature-resistant material, its outside has outer valve circle (22) to be an open column shape structure, an overall through thicker axial hole in the middle of valve circle (22) axle center outside, axial hole inner wall smooth closely cooperates installation valve rod (39), axial hole upper inside wall have an O-ring seal (3) closely cooperate valve rod (39) ensure sealing air tight, valve circle (22) waist intermediate lateral has the radial hole that vertically runs through axial hole outside, radial hole is while be communicated to preheated in cabin (26) by steam outlet tube (23), radial hole another side is communicated to the nasal mask (13) of laboratory animal (10) by respiratory airway (7), valve rod (39) smooth outer surface is trapped among in outer valve circle (22) by sealed packet, valve rod (39) is provided with back-moving spring (21) below and keeps valve rod (39) to be usually positioned at by the state of jack-up, valve rod (39) intermediate lateral have one with the hollow valve port (40) of steam outlet tube (23) isodiametric circle, hollow valve port (40) when valve rod (39) is positioned at the position by jack-up usually on valve rod (39) misplaces with the radial hole of outer valve circle (22) waist intermediate lateral, valve rod (39) is blocked in and plays insulating effect in the middle of radial hole and make steam obstructed, when pressing pressure handle ball (1) that is positioned at valve rod (39) top, valve rod (39) is moved down into the radial hole position consistency that bottom makes the hollow valve port (40) on valve rod (39) and outer valve circle (22) waist intermediate lateral, being communicated with steam on-off valve (20) makes steam circulate.
4. a kind of respiratory tract hot injury animal imitating experimental provision according to claim 1, it is characterized in that: described respiratory airway (7) is the straight-through pipeline having multiple difference to export made by insulation high-temperature-resistant material, the radial hole of its one end and steam on-off valve (20) is tightly connected, the other end is directly connected to nasal mask (13) can to laboratory animal (10) supply breathing gas or hot-air, the below of respiratory airway (7) has two passages and respectively connected the air inlet mouth of pipe (15) and the mouth of pipe of giving vent to anger (17), give the air that laboratory animal (10) provides eupnea used at any time.
5. a kind of respiratory tract hot injury animal imitating experimental provision according to claim 1, it is characterized in that: described water heater (29) is the sealing hot water tank made by the high pressure resistant sturdy material of high-temperature insulation, container bottom has temperature control electrical heating core (27) to feed water at any time Automatic-heating, be heated to uniform temperature automatically to stop ensureing that water temperature within the specific limits, water heater (29) top has an aperture and is connected to compressed gas source (30) by sealing pipeline, water heater (29) inside sealed can be kept to have certain pressure, water heater (29) is positioned at horizontal plane and has an aperture below, hot-water nozzle (37) is communicated to by sealing pipeline and hot water valve (35), when hot water valve (35) is opened, hot water (28) is sprayed water to the high-temperature heating sheet (25) preheated in cabin (26) by hot-water nozzle (37) under pressure-driven, form vapours for experimental applications.
6. a kind of respiratory tract hot injury animal imitating experimental provision according to claim 1, it is characterized in that: described nasal mask (13) is the vent hood of the bell mouth shape made by high-temperature flexible insulant, its shape experimentally animal (10) face shape and designing, its loudspeaker osculum one end is a ventilation connector be tightly connected with respiratory airway (7), its loudspeaker great Kou one end is the soft limit of circle conformed to laboratory animal (10) face shape, nasal mask (13) is connected with the nasal seal of laboratory animal (10) the soft limit of circle to have mask seal circle (12) ensure, on the soft limit of circle, nasal mask (13) is fixedly secured the head in laboratory animal (10) by fixing headband (8) in addition.
7. a kind of respiratory tract hot injury animal imitating experimental provision according to claim 1, it is characterized in that: the described air inlet mouth of pipe (15) is an air-valve device controlling one-way air inlet, the sealing of its one end is fixed on the tube wall of respiratory airway (7), near the inside of respiratory airway (7) one end, the air-breathing one-way piston (16) with damping spring (18) is installed, when presenting normal pressure in respiratory airway (7) in usual situation, damping spring (18) push-tight air-breathing from inside to outside one-way piston (16) and piston seal mouth (14) close contact, keep gas circuit sealing state of isolation, also be like this when laboratory animal (10) is exhaled or steam connects in experimentation, under reverse situation, negative pressure state is rendered as in respiratory airway (7) when laboratory animal (10) air-breathing, damping spring (18) is disengaged by gas negative pressure compression air-breathing one-way piston (16) and piston seal mouth (14), gas circuit is kept to open air-suction state, outside air provides ozone to supply laboratory animal (10) eupnea to respiratory airway (7).
8. a kind of respiratory tract hot injury animal imitating experimental provision according to claim 1, it is characterized in that: described in the mouth of pipe (17) of giving vent to anger also be a control unidirectional air-valve device of giving vent to anger contrary with the air inlet mouth of pipe (15) direction, the sealing of its one end is fixed on the tube wall of respiratory airway (7), near the inside of respiratory airway (7) sections, piston seal mouth (14) is installed, in usual situation, respiratory airway (7) is interior without pressure or when presenting negative pressure, expiration one-way piston (19) ecto-entad with damping spring (18) advances and piston seal mouth (14) close contact, keep gas circuit sealing state of isolation, under reverse situation, barotropic state is rendered as in respiratory airway (7) when laboratory animal (10) expired gas, damping spring (18) is compressed by gas positive pressure, expiration one-way piston (19) and piston seal mouth (14) disengage, gas circuit is kept to open exhaust condition, ensure that laboratory animal (10) breath is got rid of in time, also be like this when laboratory animal (10) is exhaled or steam connects in experimentation.
CN201410652093.6A 2014-11-17 2014-11-17 Respiratory tract hot injury animal imitating experimental provision Expired - Fee Related CN104306082B (en)

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