CN104302313B - 作为整体有机体的疟疾疫苗平台的啮齿动物疟原虫寄生生物 - Google Patents

作为整体有机体的疟疾疫苗平台的啮齿动物疟原虫寄生生物 Download PDF

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Publication number
CN104302313B
CN104302313B CN201380020546.7A CN201380020546A CN104302313B CN 104302313 B CN104302313 B CN 104302313B CN 201380020546 A CN201380020546 A CN 201380020546A CN 104302313 B CN104302313 B CN 104302313B
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CN
China
Prior art keywords
plasmodium
rodent
human
malaria
infected
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201380020546.7A
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English (en)
Chinese (zh)
Other versions
CN104302313A (zh
Inventor
鲁伊·米格尔·普鲁登西奥·皮尼亚泰利
玛丽亚·曼妞尔·迪亚斯·达·莫塔
安东尼奥·曼妞尔·巴尔贝罗·曼德斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Instituto de Medicina Molecular Joao Lobo Antunes
Original Assignee
Instituto de Medicina Molecular Joao Lobo Antunes
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201380020546.7A 2012-04-17 2013-04-17 作为整体有机体的疟疾疫苗平台的啮齿动物疟原虫寄生生物 Expired - Fee Related CN104302313B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PT106262 2012-04-17
PT10626212 2012-04-17
PCT/IB2013/053050 WO2013156949A1 (en) 2012-04-17 2013-04-17 Rodent plasmodium parasites as platforms for a whole-organism malaria vaccine

Publications (2)

Publication Number Publication Date
CN104302313A CN104302313A (zh) 2015-01-21
CN104302313B true CN104302313B (zh) 2018-01-26

Family

ID=48539330

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380020546.7A Expired - Fee Related CN104302313B (zh) 2012-04-17 2013-04-17 作为整体有机体的疟疾疫苗平台的啮齿动物疟原虫寄生生物

Country Status (10)

Country Link
US (1) US9655957B2 (cg-RX-API-DMAC7.html)
EP (1) EP2838554B1 (cg-RX-API-DMAC7.html)
JP (1) JP6096884B2 (cg-RX-API-DMAC7.html)
CN (1) CN104302313B (cg-RX-API-DMAC7.html)
AU (1) AU2013250814B2 (cg-RX-API-DMAC7.html)
BR (1) BR112014025823A8 (cg-RX-API-DMAC7.html)
IN (1) IN2014MN02275A (cg-RX-API-DMAC7.html)
PT (1) PT2838554T (cg-RX-API-DMAC7.html)
WO (1) WO2013156949A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201408440B (cg-RX-API-DMAC7.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104771752B (zh) * 2015-04-21 2018-01-05 中国人民解放军第三军医大学 疟疾红内期灭活全虫疫苗的新用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005063991A2 (en) * 2003-12-19 2005-07-14 Seattle Biomedical Research Institute Live genetically attenuated malaria vaccine
US7722860B2 (en) * 2004-12-03 2010-05-25 Seattle Biomedical Research Institute Live genetically engineered protozoan vaccine
FR2978048B1 (fr) * 2011-07-20 2014-10-10 Univ Paris Curie Composition vaccinale contre le paludisme

Also Published As

Publication number Publication date
US20150071966A1 (en) 2015-03-12
PT2838554T (pt) 2018-11-23
AU2013250814B2 (en) 2017-03-02
EP2838554B1 (en) 2018-08-22
EP2838554A1 (en) 2015-02-25
HK1206243A1 (en) 2016-01-08
ZA201408440B (en) 2015-12-23
BR112014025823A2 (cg-RX-API-DMAC7.html) 2017-06-20
AU2013250814A1 (en) 2014-12-04
JP6096884B2 (ja) 2017-03-15
CN104302313A (zh) 2015-01-21
JP2015514745A (ja) 2015-05-21
US9655957B2 (en) 2017-05-23
BR112014025823A8 (pt) 2017-07-25
IN2014MN02275A (cg-RX-API-DMAC7.html) 2015-08-07
WO2013156949A1 (en) 2013-10-24

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