CN104288534A - External compound oil for treating sciatica and preparation method thereof - Google Patents
External compound oil for treating sciatica and preparation method thereof Download PDFInfo
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- CN104288534A CN104288534A CN201410501828.5A CN201410501828A CN104288534A CN 104288534 A CN104288534 A CN 104288534A CN 201410501828 A CN201410501828 A CN 201410501828A CN 104288534 A CN104288534 A CN 104288534A
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- 208000008765 Sciatica Diseases 0.000 title claims abstract description 18
- 150000001875 compounds Chemical class 0.000 title claims abstract description 16
- 238000002360 preparation method Methods 0.000 title abstract description 7
- 239000000843 powder Substances 0.000 claims abstract description 24
- 239000003921 oil Substances 0.000 claims abstract description 15
- 235000019198 oils Nutrition 0.000 claims abstract description 15
- 239000004006 olive oil Substances 0.000 claims abstract description 13
- 235000008390 olive oil Nutrition 0.000 claims abstract description 13
- 239000003814 drug Substances 0.000 claims abstract description 11
- 229940079593 drug Drugs 0.000 claims abstract description 7
- 239000000203 mixture Substances 0.000 claims abstract description 7
- 238000001816 cooling Methods 0.000 claims abstract description 6
- 238000010992 reflux Methods 0.000 claims abstract description 6
- 238000003756 stirring Methods 0.000 claims abstract description 6
- 238000001291 vacuum drying Methods 0.000 claims abstract description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 6
- 241001077909 Sigesbeckia Species 0.000 claims description 7
- 238000013019 agitation Methods 0.000 claims description 5
- 239000000284 extract Substances 0.000 claims description 5
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- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 2
- 238000000034 method Methods 0.000 claims description 2
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- 235000001863 Anredera cordifolia Nutrition 0.000 abstract 2
- 241000782568 Aristolochia tuberosa Species 0.000 abstract 2
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- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
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- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
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- 206010047642 Vitiligo Diseases 0.000 description 1
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- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 description 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 description 1
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- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
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- 230000008676 import Effects 0.000 description 1
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- XMBWDFGMSWQBCA-UHFFFAOYSA-M iodide Chemical compound [I-] XMBWDFGMSWQBCA-UHFFFAOYSA-M 0.000 description 1
- 229940006461 iodide ion Drugs 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
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- KQQKGWQCNNTQJW-UHFFFAOYSA-N linolenic acid Natural products CC=CCCC=CCC=CCCCCCCCC(O)=O KQQKGWQCNNTQJW-UHFFFAOYSA-N 0.000 description 1
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- 231100000862 numbness Toxicity 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 235000021313 oleic acid Nutrition 0.000 description 1
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- 230000003204 osmotic effect Effects 0.000 description 1
- 208000035824 paresthesia Diseases 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
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- 235000015961 tonic Nutrition 0.000 description 1
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- 229940046010 vitamin k Drugs 0.000 description 1
- 239000009157 yaotongning Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8988—Gastrodia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides external compound oil for treating sciatica and a preparation method thereof. The external compound oil for treating sciatica is prepared from the following raw material medicines: 11 parts of gastrodia elata, 16 parts of aristolochia tuberosa, 23 parts of herba siegesbeckiae, 14 parts of Chinese holly leaf, 8 parts of pleione, 13 parts of yam rhizome, 8 parts of anredera cordifolia, 36 parts of olive oil and 24 parts of emu oil. The preparation method comprises the following steps: A. taking aristolochia tuberosa, herba siegesbeckiae, Chinese holly leaf, pleione, yam rhizome and anredera cordifolia, adding pure water being 7 times of the weight of the raw material medicines to perform reflux extraction for 4 times and 3 hours each time, mixing the decoction, filtering, concentrating the decoction to obtain extractum with relative density of 1.20-1.35 (60 DEG C), vacuum-drying the extractum, and preparing the extractum into 300mesh powder; B. preparing the gastrodia elata into 300-400mesh powder; C. adding the olive oil and the emu oil in a stirrer to be stirred uniformly; D. adding the powder in step A, the powder in step B and the mixture in step C into an ultrasonic stirrer, ultrasonically stirring for 1-1.5 hours at 60-65 DEG C, and cooling to obtain the external compound oil.
Description
Technical field
The invention belongs to technical field of medicine preparation, be specially a kind of external compound oil for the treatment of sciatica and preparation method thereof.
Background technology
Sciatica refers to along sciatic nerve distributed areas, based on the radiated pain outside outside, instep on rear side of buttocks, thigh, after shank.And sciatica early symptom generally shows as lower limb pain, numbness etc.Sciatica is many with one-sided morbidity, mainly betides adult male, and onset mostly is acute or subacute.Onset is different with cause of disease difference.Modal prolapse of lumbar intervertebral disc, is everlasting firmly, bends over or under the inducement such as aggravating activities, acute or subacute onset.Minority is chronic onset.Pain often from waist after side buttocks, thigh, popliteal nest, little leg outer side and foot radiate, in burning sample or cutting pains, cough and firmly time pain can aggravate, night is more very.Sciatica is the syndrome based on sciatic nerve pathway and distributed areas pain.
Western medicine: analgesic, vitamin B complex, short distance corticosteroid hormone is oral can favourablely be recovered.Chinese medicine: external use plaster, the pure Traditional Chinese medicine external medicinal such as pasting at all times as Venenum apis has good therapeutic effect to sciatica.Physical therapy: acute stage can use ultrashort wave therapy, the treatments such as erythema dose ultraviolet radiation.Chronic phase, can import with short wave therapy unidirectional current iodide ion.
Summary of the invention
The object of this invention is to provide a kind of external compound oil for the treatment of sciatica and preparation method thereof.
The present invention treats the external compound oil of sciatica; Be made up of the crude drug of following parts by weight: 10 ~ 12 parts, Rhizoma Gastrodiae, back of the body Serpentis raw 15 ~ 19 Fen, Herba Siegesbeckiaes 18 ~ 25 parts, Folium Mahoniae 12 ~ 15 parts, Aspidlsiraelatior 8 ~ 10 parts of, Rhizoma Dioscoreae Septemlobae 12 ~ 15 parts, Bulbilus boussingaultiae pseudobaselloidis 8 ~ 10 parts, 35 ~ 40 parts, olive oil, fat of Oromaius norvaehollandeae 22 ~ 28 parts.
As optimization, this external compound oil, is made up of the crude drug of following parts by weight: 11 parts, Rhizoma Gastrodiae, back of the body Serpentis raw 16 Fen, Herba Siegesbeckiaes 23 parts, Folium Mahoniae 14 parts, Aspidlsiraelatior 8 parts of, Rhizoma Dioscoreae Septemlobae 13 parts, Bulbilus boussingaultiae pseudobaselloidis 8 parts, 36 parts, olive oil, fat of Oromaius norvaehollandeae 24 parts.
Prepare the method for this external compound oil, comprise the following steps:
A, get back of the body Serpentis Sheng, Herba Siegesbeckiae, Folium Mahoniae, Aspidlsiraelatior, Rhizoma Dioscoreae Septemlobae, the Bulbilus boussingaultiae pseudobaselloidis of described parts by weight, add the pure water reflux, extract, 4 times of 7 times of weight, each 3 hours, collecting decoction, filter, be condensed into the extractum of 1.20 ~ 1.35 (60 ° of C), after vacuum drying, make 300 order powder;
B, the Rhizoma Gastrodiae getting described parts by weight make 300 ~ 400 order powder;
C, the olive oil getting described parts by weight, fat of Oromaius norvaehollandeae add in blender and stir;
D, by the mixture in the powder in steps A, the powder in step B, step C, join in ultrasonic stirrer, under 60 ~ 65 DEG C of conditions, ultrasonic agitation 1 ~ 1.5 hour, cooling.
In prescription of the present invention, the raw heat-clearing and toxic substances removing of back of the body Serpentis, suppressing the hyperactive liver to relieve the wind syndrome, cough-relieving, hemostasis, improving eyesight removing nebula.Rhizoma Gastrodiae endogenous wind stopping, arresting convulsion; Control dizzy pupil, wind syndrome of head is had a headache, numb limbs and tense tendons, hemiplegia, aphasia, pediatric epilepsy scared wind symptom.Herba Siegesbeckiae wind-damp dispelling, the meridian dredging, heat-clearing and toxic substances removing, blood pressure lowering; For rheumatic arthralgia, numb limbs and tense tendons; Apoplexy, hands and feet caused by paralysis; Carbuncle sore tumefacting virus, eczema pruritus; Hypertension.Folium Mahoniae clearind deficient heat, liver and kidney tonifying, wind-damp dispelling; Main hectic fever due to deficiency of YIN; Cough spitting of blood; Have a dizzy spell; Soreness of the waist and knees; Rheumatic arthralgia; Vitiligo.Aspidlsiraelatior energy promoting blood circulation to remove blood stasis, tonify deficiency cough-relieving; Contribute to controlling traumatic injury, bones and muscles pain due to rheumatism, lumbago, cough due to deficiency of the lung, spitting of blood effect.Rhizoma Dioscoreae Septemlobae dispels the wind, dampness removing; Dispelling the wind and dampness pathogens insensitive impediment, lumbocrural pain, dysuria, stranguria with turbid discharge, seminal emission, damp and hot sore.The micro-hardship of Bulbilus boussingaultiae pseudobaselloidis, warm in nature, strengthening by means of tonics, scattered silt pain relieving, except wind damp eliminating, reduce blood fat, blood pressure, enrich blood and invigorate blood circulation.Olive oil is rich in abundant monounsaturated fatty acid, i.e. oleic acid and linoleic acid, linolenic acid, also has vitamin A, vitamin B, vitamin D, vitamin E, vitamin K and polyphenoils etc.Fat of Oromaius norvaehollandeae has percdation ability, can heal burn, otch, erythra and other dermatosis; Fat of Oromaius norvaehollandeae can also have analgesic effect to myalgia; Therapeutical effect is had to injured, the arthritis that cause due to sports.
The external compound oil of this treatment sciatica, matrix oil is made up of olive oil and fat of Oromaius norvaehollandeae compound, has good analgesia and osmotic effect; The multiple active drug composition contained, dispelling wind and removing obstruction in the collateral, scattered silt pain relieving, damp eliminating of invigorating blood circulation, is used for the treatment of sciatica remarkably productive, safe and effective.
Detailed description of the invention
The invention will be further described for embodiment plan given below; but can not be interpreted as it is limiting the scope of the invention; those skilled in the art to nonessential improvement and adjustment more of the present invention, still belong to protection scope of the present invention according to content of the present invention.
Embodiment 1,
A, get back of the body Serpentis raw 16 Ke, Herba Siegesbeckiaes 23 grams, Folium Mahoniae 14 grams, Aspidlsiraelatior 8 grams of, Rhizoma Dioscoreae Septemlobae 13 grams, Bulbilus boussingaultiae pseudobaselloidis 8 grams, add the pure water reflux, extract, 4 times of 7 times of weight, each 3 hours, collecting decoction, filter, be condensed into the extractum of 1.20 ~ 1.35 (60 ° of C), after vacuum drying, make 300 order powder;
B, get Rhizoma Gastrodiae 11 and restrain into 300 ~ 400 order powder;
C, get 36 grams, olive oil, fat of Oromaius norvaehollandeae 24 grams adds in blender and stirs;
D, by the mixture in the powder in steps A, the powder in step B, step C, join in ultrasonic stirrer, under 60 ~ 65 DEG C of conditions, ultrasonic agitation 1 ~ 1.5 hour, cooling.
Embodiment 2,
A, get back of the body Serpentis raw 19 Ke, Herba Siegesbeckiaes 25 grams, Folium Mahoniae 15 grams, Aspidlsiraelatior 10 grams of, Rhizoma Dioscoreae Septemlobae 15 grams, Bulbilus boussingaultiae pseudobaselloidis 10 grams, add the pure water reflux, extract, 4 times of 7 times of weight, each 3 hours, collecting decoction, filter, be condensed into the extractum of 1.20 ~ 1.35 (60 ° of C), after vacuum drying, make 300 order powder;
B, get Rhizoma Gastrodiae 12 and restrain into 300 ~ 400 order powder;
C, get 40 grams, olive oil, fat of Oromaius norvaehollandeae 28 grams adds in blender and stirs;
D, by the mixture in the powder in steps A, the powder in step B, step C, join in ultrasonic stirrer, under 60 ~ 65 DEG C of conditions, ultrasonic agitation 1 ~ 1.5 hour, cooling.
Embodiment 3,
A, get back of the body Serpentis raw 15 Ke, Herba Siegesbeckiaes 18 grams, Folium Mahoniae 12 grams, Aspidlsiraelatior 8 grams of, Rhizoma Dioscoreae Septemlobae 12 grams, Bulbilus boussingaultiae pseudobaselloidis 8 grams, add the pure water reflux, extract, 4 times of 7 times of weight, each 3 hours, collecting decoction, filter, be condensed into the extractum of 1.20 ~ 1.35 (60 ° of C), after vacuum drying, make 300 order powder;
B, get Rhizoma Gastrodiae 10 and restrain into 300 ~ 400 order powder;
C, get 35 grams, olive oil, fat of Oromaius norvaehollandeae 22 grams adds in blender and stirs;
D, by the mixture in the powder in steps A, the powder in step B, step C, join in ultrasonic stirrer, under 60 ~ 65 DEG C of conditions, ultrasonic agitation 1 ~ 1.5 hour, cooling.
Pertinent clinical data is as follows:
Physical data: observe case 164 example, man 94 example, female 70 example; Max age 63 years old, minimum 18 years old, average (39 ± 5.73) year; The shortest person of the course of disease 1 week, the longest 29 a, average (8 ± 3.46) a.The case sciatica patient meeting diagnostic criteria is divided into 4 groups at random, often organizes 41 people, three treatment groups and a matched group.
Diagnostic criteria: diagnostic criteria with the classical symptom of sciatica and sign for foundation.(1) sciatic nerve distributed areas pain or radiated pain; (2) have and subtract pain posture (crouch when sleeping to strong side, to suffer from knee joint micro-in the wrong, when standing, centre of body weight shifts to strong side) or limitation of activity; (3) pressure pain point tenderness and dragging pain is had; (4) suffer from lower limb paraesthesia, muscular strength goes down and tendon reflex weakens or disappears; (5) straight-leg raising test, strengthens test positive; (6) auxiliary lumbosacral spine x line (sheet) shows that lumbar lateral curvature or physiologic radian diminish or disappear, narrowing of intervertebral space, and CT/MRI checks, gets rid of the factor such as intervertebral disk hernia and tumor.
Therapeutic Method: treatment group: adopt the embodiment of the present invention 1, embodiment 2, embodiment 3 to treat the external compound oil of sciatica respectively, be applied to Tiaokou cave, Xuanzhong cave, HUANTIAO acupoint, point bl 36, every day 4 times.Matched group: YAOTONGNING JIAONANG (Chengde JingFuKang pharmacy Group Co., Ltd's production) is oral, each 3, every day 2 times.2 groups was all 1 course for the treatment of with 30 d.2 groups all coordinate acupuncture and moxibustion therapy, and acupuncture and moxibustion therapy was 1 course for the treatment of with 15 d.
Curative effect determinate standard: cure: lumbago and skelalgia and related symptoms disappear completely or close to disappearing, positive sign is turned out cloudy, and can recover original work, function, quality of life, symptom, somatic feature score improve in 90%, 3 months without recurrence; Effective: lumbago and skelalgia symptom partial disappearance, sign alleviates, and function, quality of life, symptom, somatic feature score improve 70% ~ 89%; , can resume work; Take a turn for the better: lumbago and skelalgia symptom partial disappearance, still has positive sign, function, quality of life, symptom, somatic feature score improve 50% ~ 69%, and can be engaged in lighter work, counterweight physical work has impact; Invalid: after treatment, function, quality of life, symptom, sign are not improved or alleviate, and even increase the weight of, symptom integral improves <50%, can not participate in normal work.Efficacy result is in table 1.
Statistical analysis: adopt SPSS 18.0 statistics software processes, measurement data mean ± standard deviation (x ± s) represents, adopts t inspection; The comparison of enumeration data rate adopts x
2inspection.Difference has statistical significance (P<0.05).
Claims (3)
1. treat the external compound oil of sciatica for one kind; It is characterized in that by the crude drug of following parts by weight: 10 ~ 12 parts, Rhizoma Gastrodiae, raw 15 ~ 19 Fen, Herba Siegesbeckiaes 18 ~ 25 parts of back of the body Serpentis, Folium Mahoniae 12 ~ 15 parts, Aspidlsiraelatior 8 ~ 10 parts of, Rhizoma Dioscoreae Septemlobae 12 ~ 15 parts, Bulbilus boussingaultiae pseudobaselloidis 8 ~ 10 parts, 35 ~ 40 parts, olive oil, fat of Oromaius norvaehollandeae 22 ~ 28 parts are made.
2. external compound oil according to claim 1, it is characterized in that being made up of the crude drug of following parts by weight: 11 parts, Rhizoma Gastrodiae, back of the body Serpentis raw 16 Fen, Herba Siegesbeckiaes 23 parts, Folium Mahoniae 14 parts, Aspidlsiraelatior 8 parts of, Rhizoma Dioscoreae Septemlobae 13 parts, Bulbilus boussingaultiae pseudobaselloidis 8 parts, 36 parts, olive oil, fat of Oromaius norvaehollandeae 24 parts.
3. prepare a method for external compound oil described in any one of claim 1 ~ 2, it is characterized in that comprising the following steps:
A, get back of the body Serpentis Sheng, Herba Siegesbeckiae, Folium Mahoniae, Aspidlsiraelatior, Rhizoma Dioscoreae Septemlobae, the Bulbilus boussingaultiae pseudobaselloidis of described parts by weight, add the pure water reflux, extract, 4 times of 7 times of weight, each 3 hours, collecting decoction, filter, be condensed into the extractum of 1.20 ~ 1.35 (60 ° of C), after vacuum drying, make 300 order powder;
B, the Rhizoma Gastrodiae getting described parts by weight make 300 ~ 400 order powder;
C, the olive oil getting described parts by weight, fat of Oromaius norvaehollandeae add in blender and stir;
D, by the mixture in the powder in steps A, the powder in step B, step C, join in ultrasonic stirrer, under 60 ~ 65 DEG C of conditions, ultrasonic agitation 1 ~ 1.5 hour, cooling.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101670033A (en) * | 2009-09-30 | 2010-03-17 | 李炳华 | Ointment for curing protrusion of lumbar vertebral disc, sciatica, pain of neck, shoulder and legs, rheumatoid arthritis and hyperosteogeny |
| WO2012075447A2 (en) * | 2010-12-03 | 2012-06-07 | Warsaw Orthopedic, Inc. | Compositions and methods for delivering clonidine and bupivacaine to a target tissue site |
| CN103040977A (en) * | 2013-01-09 | 2013-04-17 | 上海浦东高星生物技术研究所 | Chinese patent drug for treating sciatica |
-
2014
- 2014-09-27 CN CN201410501828.5A patent/CN104288534A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101670033A (en) * | 2009-09-30 | 2010-03-17 | 李炳华 | Ointment for curing protrusion of lumbar vertebral disc, sciatica, pain of neck, shoulder and legs, rheumatoid arthritis and hyperosteogeny |
| WO2012075447A2 (en) * | 2010-12-03 | 2012-06-07 | Warsaw Orthopedic, Inc. | Compositions and methods for delivering clonidine and bupivacaine to a target tissue site |
| CN103040977A (en) * | 2013-01-09 | 2013-04-17 | 上海浦东高星生物技术研究所 | Chinese patent drug for treating sciatica |
Non-Patent Citations (4)
| Title |
|---|
| 屠佑堂: "《中医实用诊疗大全：全2册（上册）》", 31 March 2013 * |
| 朱成全等: "《防治"四高"药膳大全》", 28 February 2014 * |
| 柴瑞霁: "中医治疗坐骨神经痛临床进展", 《黑龙江中医药》 * |
| 江西药科学校革命委员会: "《草药手册》", 31 January 1970 * |
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