CN104274148A - Imaging system - Google Patents

Imaging system Download PDF

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Publication number
CN104274148A
CN104274148A CN201410508158.XA CN201410508158A CN104274148A CN 104274148 A CN104274148 A CN 104274148A CN 201410508158 A CN201410508158 A CN 201410508158A CN 104274148 A CN104274148 A CN 104274148A
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CN
China
Prior art keywords
optical filter
imaging system
light source
optical
sensitive detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410508158.XA
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Chinese (zh)
Inventor
詹诗杰
周仪光
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ANHUI ZHONGKE MEDICAL IMAGING TECHNOLOGY Co Ltd
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ANHUI ZHONGKE MEDICAL IMAGING TECHNOLOGY Co Ltd
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Publication date
Application filed by ANHUI ZHONGKE MEDICAL IMAGING TECHNOLOGY Co Ltd filed Critical ANHUI ZHONGKE MEDICAL IMAGING TECHNOLOGY Co Ltd
Priority to CN201410508158.XA priority Critical patent/CN104274148A/en
Publication of CN104274148A publication Critical patent/CN104274148A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/045Control thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0638Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/06Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
    • A61B1/0646Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements with illumination filters

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endoscopes (AREA)

Abstract

The invention discloses an imaging system. The imaging system comprises an endoscope unit, a control unit and an image processing unit. The endoscope unit is used for acquiring optical signals and comprises a front end portion and a cavity portion, a light source lens and an objective lens are embedded onto the front end portion, a light source, an optical filter and a detection device are arranged in the cavity portion, optical signals sent by the light source includes near infrared light and illumination light, and the light source lens, the objective lens, the optical filter and the detection device are arranged sequentially in the transmission direction of the optical signals sent by the light source. The optical filter comprises a first optical filter and a second optical filter; the detection device comprises a visible light detection device matched with the first optical filter and a fluorescence detection device matched with the second optical filter. The control unit is connected with the endoscope unit through optical cables and electric cables and used for adjusting the distance between the objective lens and the detection device; the image processing unit is connected with the endoscope unit through optical cables and used for processing the optical signals received by the detection device.

Description

Imaging system
Technical field
The present invention relates to image imaging field, particularly, relate to a kind of imaging system.
Background technology
Molecular imaging is the frontier combined with imaging in vivo by molecular biology occurred in recent years, and it can make cell function visual, and non-invasively can follow the tracks of molecular process in biological living inside.This technology can also improve clinical treatment by optimizing the clinical front of novel drugs with clinical trial, this will due to its in early days and diagnose accurately and bring very large economic impact, that can predict Molecular imaging techniques develops the major transformation that may cause clinical treatment rapidly.
In the art, the system of being carried out imaging by endoscope is always all relatively backward, usually by simple CCD camera, capture is carried out to inside, in the process of capture, owing to requiring higher to the definition of internal image, need very high focusing precision, and existing endoscope carries out imaging to picture generally all can not well focus on, so designing a kind of endoscopic imaging system that can precisely focus on becomes a kind of urgent problem.
Summary of the invention
The object of this invention is to provide a kind of imaging system and formation method, this imaging system and formation method overcome endoscope and carry out to picture the problem that imaging generally all can not well focus on, and provide a kind of imaging system that can focus on very well.
To achieve these goals, the invention provides a kind of imaging system, this imaging system comprises: endoscopic unit, described endoscopic unit is for gathering optical signal, this endoscopic unit comprises leading section and cavity portion, described leading section is embedded with light source eyeglass and object lens, the inside of described cavity portion is provided with light source, optical filter and sensitive detection parts, the optical signal that described light source sends comprises near infrared light and illumination light, the transmission direction of the optical signal sent at described light source is disposed with: described light source eyeglass, described object lens, described optical filter and described sensitive detection parts, described optical filter comprises first optical filter and the second optical filter that can switch, described sensitive detection parts comprise: the visible-light detector part matched with described first optical filter and the fluorescence detection device matched with described second optical filter,
Control unit, is connected to described endoscopic unit by optical cable and cable, is configured to control described endoscopic unit and adjusts distance between described object lens and described sensitive detection parts;
Graphics processing unit, is connected to described endoscopic unit by optical cable, is configured to the optical signal processing the acceptance of described sensitive detection parts.
Preferably, described control unit comprises: analysis processor and the actuator be connected with described analysis processor, described analysis processor is configured to be connected to described endoscopic unit to judge whether accurate focusing according to described optical signal, when accurately not focusing, within the scope of predeterminable range, described analysis processor controls described actuator and adjusts distance between described object lens and described sensitive detection parts.
Preferably, described actuator comprises: motor and driver, and described motor is configured to adjust distance between described object lens and described sensitive detection parts in response to the control of described analysis processor to drive described driver.
Preferably, described graphics processing unit comprises that the fluoroscopic image that sets gradually strengthens module, fluoroscopic image adds pseudo-colours module, image co-registration module and display apparatus module.
Preferably, described fluorescence detection device is: fluorescence camera;
Described visible-light detector part is: CCD camera.
Preferably, the outer surface of described optical cable and cable is enclosed with flexible pipe.
By above-mentioned embodiment, imaging system of the present invention overcomes the problem that endoscopic unit can not well focus on picture imaging, and this kind of endoscopic unit can gather white light and fluorescence, and can change by switching first optical filter and the second optical filter the kind gathered.
Other features and advantages of the present invention are described in detail in detailed description of the invention part subsequently.
Accompanying drawing explanation
Accompanying drawing is used to provide a further understanding of the present invention, and forms a part for description, is used from explanation the present invention, but is not construed as limiting the invention with detailed description of the invention one below.In the accompanying drawings:
Fig. 1 is the FB(flow block) of the imaging system that a kind of detailed description of the invention of the present invention is described; And
Fig. 2 is the three-dimensional structure diagram of the endoscopic unit that a kind of detailed description of the invention of the present invention is described.
Description of reference numerals
1 leading section 2 cavity portion
11 light source eyeglass 12 object lens
21 light source 211 first optical filters
212 second optical filter 22 sensitive detection parts.
Detailed description of the invention
Below in conjunction with accompanying drawing, the specific embodiment of the present invention is described in detail.Should be understood that, detailed description of the invention described herein, only for instruction and explanation of the present invention, is not limited to the present invention.
In the detailed description of the invention of a kind of imaging system of the present invention, this imaging system comprises: endoscopic unit, described endoscopic unit is for gathering optical signal, this endoscopic unit comprises leading section 1 and cavity portion 2, leading section 1 is embedded with light source eyeglass 11 and object lens 12, the inside of cavity portion 2 is provided with light source 21, optical filter and sensitive detection parts 22, the optical signal that light source 21 sends comprises near infrared light and illumination light, the transmission direction of the optical signal sent at light source 21 is disposed with: light source eyeglass 11, object lens 12, optical filter and sensitive detection parts 22; Optical filter comprises first optical filter 211 and second optical filter 212 that can switch; Sensitive detection parts 22 comprise: the visible-light detector part 22 matched with the first optical filter 211 and the fluorescence detection device 22 matched with the second optical filter 212;
Control unit, is connected to endoscopic unit by optical cable and cable, is configured to control described endoscopic unit and adjusts distance between described object lens 12 and described sensitive detection parts 22;
Graphics processing unit, is connected to endoscopic unit by optical cable, is configured to the optical signal processing sensitive detection parts 22 acceptance.
Be connected by slidably connector between described object lens 12 with described sensitive detection parts 22, described object lens 12 can slide with the relative position of described sensitive detection parts 22, and can do relative motion between object lens 12 and sensitive detection parts 22 and move toward one another etc.By above-mentioned embodiment, near infrared light and illumination light all send and pass light source eyeglass 11 by endoscopic unit of the present invention from the cavity portion 2 of endoscopic unit to be irradiated in being penetrated on the surface of object, the light be reflected back is received by object lens 12, optical filter and sensitive detection parts 22, thus realizes gathering white light and fluoroscopic image; When this imaging system uses, light source eyeglass 11 can play the effect of protection to light source 21; Control unit had not only connected endoscopic unit by optical cable but also by cable, and control unit receives optical signal and control signal makes endoscopic unit to focus on.
Endoscopic unit below in conjunction with accompanying drawing 1 and accompanying drawing 2 is further detailed the present invention, and in the present invention, imaging system can be good at focusing on and can realize the fusion display of white light and fluoroscopic image.
In the detailed description of the invention of a kind of imaging system of the present invention, control unit can comprise: analysis processor and the actuator be connected with analysis processor, analysis processor is configured to be connected to endoscopic unit to judge whether accurate focusing according to optical signal, when accurately not focusing, within the scope of predeterminable range, described actuator adjusts the distance between described object lens 12 and described sensitive detection parts 22.
In this kind of preferred implementation, in order to determine that best focusing realizes the accurate focusing of endoscopic unit, actuator can comprise: motor and driver, motor is configured to adjust distance between described object lens 12 and described sensitive detection parts 22 in response to the control of described analysis processor to drive described driver, wherein, driver can be an automaton, automatically controls focal length and aims at, this kind of alignment does not need manually to operate, and actuator can realize automatic calibration.
In this kind of preferred implementation, in order to realize the fusion of fluoroscopic image and White-light image and strengthen and by image display over the display, graphics processing unit comprises that the fluoroscopic image that sets gradually strengthens module, fluoroscopic image adds pseudo-colours module, image co-registration module and display apparatus module.
In this kind of embodiment, fluorescence detection device 22 is: fluorescence camera, and this kind of camera can realize the collection to fluoroscopic image, and visible-light detector part 22 is: CCD camera, and this kind of camera can realize the collection to White-light image.
In this kind of embodiment, the outer surface of optical cable and cable is enclosed with flexible pipe, by above-mentioned embodiment, plays the effect of protection reinforcing to optical cable and cable.
In sum, near infrared light and illumination light all send and pass light source eyeglass 11 by endoscopic unit of the present invention from the cavity portion 2 of endoscopic unit to be irradiated in being penetrated on the surface of object, the light be reflected back is received by object lens 12, optical filter and sensitive detection parts 22, thus realizes gathering white light and fluoroscopic image; When this imaging system uses, light source eyeglass 11 can play the effect of protection to light source 21; Control unit had not only connected endoscopic unit by optical cable but also by cable, control unit receives optical signal and control signal makes endoscopic unit to focus on, can determine that best focusing realizes the accurate focusing of endoscopic unit by analysis processor and the actuator be connected with analysis processor, by graphics processing unit, the fusion of fluoroscopic image and White-light image be strengthened and by the image display after strengthening over the display.
Below the preferred embodiment of the present invention is described in detail by reference to the accompanying drawings; but; the present invention is not limited to the detail in above-mentioned embodiment; within the scope of technical conceive of the present invention; can carry out multiple simple variant to technical scheme of the present invention, these simple variant all belong to protection scope of the present invention.
It should be noted that in addition, each concrete technical characteristic described in above-mentioned detailed description of the invention, in reconcilable situation, can be combined by any suitable mode, in order to avoid unnecessary repetition, the present invention illustrates no longer separately to various possible compound mode.
In addition, also can carry out combination in any between various different embodiment of the present invention, as long as it is without prejudice to thought of the present invention, it should be considered as content disclosed in this invention equally.

Claims (6)

1. an imaging system, it is characterized in that, this imaging system comprises: endoscopic unit, described endoscopic unit is for gathering optical signal, this endoscopic unit comprises leading section (1) and cavity portion (2), described leading section (1) is embedded with light source eyeglass (11) and object lens (12), the inside of described cavity portion (2) is provided with light source (21), optical filter and sensitive detection parts (22), the optical signal that described light source (21) sends comprises near infrared light and illumination light, the transmission direction of the optical signal sent at described light source (21) is disposed with: described light source eyeglass (11), described object lens (12), described optical filter and described sensitive detection parts (22), described optical filter comprises first optical filter (211) and the second optical filter (212) that can switch, described sensitive detection parts (22) comprising: the visible-light detector part (22) matched with described first optical filter (211) and the fluorescence detection device (22) matched with described second optical filter (212),
Control unit, is connected to described endoscopic unit by optical cable and cable, is configured to control described endoscopic unit and adjusts distance between described object lens (12) and described sensitive detection parts (22);
Graphics processing unit, is connected to described endoscopic unit by optical cable, is configured to process the optical signal that described sensitive detection parts (22) accept.
2. imaging system according to claim 1, it is characterized in that, described control unit comprises: analysis processor and the actuator be connected with described analysis processor, described analysis processor is configured to be connected to described endoscopic unit to judge whether accurate focusing according to described optical signal, when accurately not focusing, within the scope of predeterminable range, described analysis processor controls described actuator and adjusts distance between described object lens (12) and described sensitive detection parts (22).
3. imaging system according to claim 2, it is characterized in that, described actuator comprises: motor and driver, and described motor is configured to adjust distance between described object lens (12) and described sensitive detection parts (22) in response to the control of described analysis processor to drive described driver.
4. imaging system according to claim 2, is characterized in that, described graphics processing unit comprises that the fluoroscopic image that sets gradually strengthens module, fluoroscopic image adds pseudo-colours module, image co-registration module and display apparatus module.
5. imaging system according to claim 1, is characterized in that, described fluorescence detection device (22) is: fluorescence camera;
Described visible-light detector part (22) is: CCD camera.
6. imaging system according to claim 1, is characterized in that, the outer surface of described optical cable and cable is enclosed with flexible pipe.
CN201410508158.XA 2014-09-28 2014-09-28 Imaging system Pending CN104274148A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105049689A (en) * 2015-06-30 2015-11-11 广东实联医疗器械有限公司 Image processing enhancing, video recording and display circuit for medical endoscope
CN108040243A (en) * 2017-12-04 2018-05-15 南京航空航天大学 Multispectral 3-D visual endoscope device and image interfusion method
CN109662695A (en) * 2019-01-16 2019-04-23 北京数字精准医疗科技有限公司 Fluorescent molecules imaging system, device, method and storage medium
CN110772208A (en) * 2019-10-31 2020-02-11 深圳开立生物医疗科技股份有限公司 Method, device and equipment for acquiring fluorescence image and endoscope system
WO2021051222A1 (en) * 2019-09-16 2021-03-25 北京数字精准医疗科技有限公司 Endoscope system, mixed light source, video acquisition device and image processor
CN115153399A (en) * 2022-09-05 2022-10-11 浙江华诺康科技有限公司 Endoscope system

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US20110028790A1 (en) * 2004-09-24 2011-02-03 Vivid Medical, Inc. Disposable endoscopic access device and portable display
US20110228064A1 (en) * 2010-03-18 2011-09-22 Olympus Corporation Endoscope system, imaging apparatus, and control method
CN102984989A (en) * 2010-08-30 2013-03-20 奥林巴斯医疗株式会社 Endoscope
CN202960439U (en) * 2012-08-01 2013-06-05 深圳市雷迈科技有限公司 Multi-purpose light source for medical endoscope
CN103654700A (en) * 2013-12-31 2014-03-26 中国人民武装警察部队总医院 Fluorescent endoscope imaging system and method

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Publication number Priority date Publication date Assignee Title
CN1415267A (en) * 2001-10-18 2003-05-07 韩国电工技术研究院 Fluorescent endoscope device and method for imaging in body tissue by utilizing sucn devoce
US20040225222A1 (en) * 2003-05-08 2004-11-11 Haishan Zeng Real-time contemporaneous multimodal imaging and spectroscopy uses thereof
US20110028790A1 (en) * 2004-09-24 2011-02-03 Vivid Medical, Inc. Disposable endoscopic access device and portable display
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CN101943796A (en) * 2010-08-26 2011-01-12 杨晓峰 Multi-spectrum endoscopic optics switching system
CN102984989A (en) * 2010-08-30 2013-03-20 奥林巴斯医疗株式会社 Endoscope
CN202960439U (en) * 2012-08-01 2013-06-05 深圳市雷迈科技有限公司 Multi-purpose light source for medical endoscope
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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105049689A (en) * 2015-06-30 2015-11-11 广东实联医疗器械有限公司 Image processing enhancing, video recording and display circuit for medical endoscope
CN105049689B (en) * 2015-06-30 2016-05-18 广东实联医疗器械有限公司 A kind of image of medical endoscope is processed enhancing, video record and display circuit
CN108040243A (en) * 2017-12-04 2018-05-15 南京航空航天大学 Multispectral 3-D visual endoscope device and image interfusion method
CN109662695A (en) * 2019-01-16 2019-04-23 北京数字精准医疗科技有限公司 Fluorescent molecules imaging system, device, method and storage medium
WO2021051222A1 (en) * 2019-09-16 2021-03-25 北京数字精准医疗科技有限公司 Endoscope system, mixed light source, video acquisition device and image processor
CN110772208A (en) * 2019-10-31 2020-02-11 深圳开立生物医疗科技股份有限公司 Method, device and equipment for acquiring fluorescence image and endoscope system
CN110772208B (en) * 2019-10-31 2022-04-15 深圳开立生物医疗科技股份有限公司 Method, device and equipment for acquiring fluorescence image and endoscope system
CN115153399A (en) * 2022-09-05 2022-10-11 浙江华诺康科技有限公司 Endoscope system
CN115153399B (en) * 2022-09-05 2022-12-09 浙江华诺康科技有限公司 Endoscope system

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Application publication date: 20150114