CN104271152B - 拔出牙齿的方法 - Google Patents

拔出牙齿的方法 Download PDF

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Publication number
CN104271152B
CN104271152B CN201380023125.XA CN201380023125A CN104271152B CN 104271152 B CN104271152 B CN 104271152B CN 201380023125 A CN201380023125 A CN 201380023125A CN 104271152 B CN104271152 B CN 104271152B
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China
Prior art keywords
tooth
collagenase
another embodiment
composition
extraction
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CN201380023125.XA
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English (en)
Chinese (zh)
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CN104271152A (zh
Inventor
凯伦·玛丽恩卡卡尔曼尼
叶夫根尼·维恩伯格
约瑟夫·加夫尼
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PROTEOLEASE Ltd
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PROTEOLEASE Ltd
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Publication of CN104271152A publication Critical patent/CN104271152A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00Dental auxiliary appliances
    • A61C19/06Implements for therapeutic treatment
    • A61C19/063Medicament applicators for teeth or gums, e.g. treatment with fluorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24Metalloendopeptidases (3.4.24)
    • C12Y304/24003Microbial collagenase (3.4.24.3)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C3/00Dental tools or instruments
    • A61C3/14Dentists' forceps or the like for extracting teeth
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24Metalloendopeptidases (3.4.24)
    • C12Y304/24007Interstitial collagenase (3.4.24.7), i.e. matrix metalloprotease 1 or MMP1
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04CROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS
    • F04C2270/00Control; Monitoring or safety arrangements
    • F04C2270/04Force
    • F04C2270/041Controlled or regulated

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dentistry (AREA)
  • Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN201380023125.XA 2012-05-01 2013-05-01 拔出牙齿的方法 Active CN104271152B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261640743P 2012-05-01 2012-05-01
US61/640,743 2012-05-01
PCT/IL2013/050367 WO2013164822A1 (en) 2012-05-01 2013-05-01 Methods for extracting a tooth

Publications (2)

Publication Number Publication Date
CN104271152A CN104271152A (zh) 2015-01-07
CN104271152B true CN104271152B (zh) 2016-08-17

Family

ID=49514270

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380023125.XA Active CN104271152B (zh) 2012-05-01 2013-05-01 拔出牙齿的方法

Country Status (10)

Country Link
US (1) US10016492B2 (enExample)
EP (1) EP2844276B1 (enExample)
JP (1) JP2015521169A (enExample)
CN (1) CN104271152B (enExample)
AU (1) AU2013255400A1 (enExample)
BR (1) BR112014027347A2 (enExample)
CA (1) CA2872227A1 (enExample)
IL (1) IL235435B (enExample)
IN (1) IN2014MN02422A (enExample)
WO (1) WO2013164822A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015140802A2 (en) 2014-03-20 2015-09-24 Technion Research & Development Foundation Limited Delivery system comprising a proteolytic enzyme or effector thereof for use in a method for oral treatment and uses thereof
KR101551344B1 (ko) 2014-04-14 2015-09-08 한국기계연구원 치아 발치 방향 도출 시스템 및 이를 이용한 발치 방향 도출 방법
US11033357B1 (en) * 2020-11-12 2021-06-15 King Abdulaziz University Methods for tooth extraction using a thermoelectric device
EP4448752A4 (en) * 2021-12-14 2025-06-18 Ramot at Tel-Aviv University Ltd. Modified recombinant collagenase, compositions comprising the same and uses thereof in dental related procedures

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3719367A1 (de) * 1987-06-10 1988-12-29 Duncker Martin Dr Verwendung von den stoffwechsel und/oder die struktureigenschaften von kollagen beeinflussenden wirksubstanzen in der kieferorthopaedie
WO2004041106A1 (en) * 2002-11-01 2004-05-21 Bas Medical, Inc. Methods and systems for enabling and stabilizing tooth movement

Family Cites Families (20)

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Publication number Priority date Publication date Assignee Title
US5139944A (en) 1985-08-10 1992-08-18 Biophram (Uk) Limited Collagen-specific enzyme with platelet aggregation inhibition properties
US5709873A (en) 1988-02-26 1998-01-20 Niels Bukh A/S Method of treating conditions of teeth and their supporting tissue
US7947270B2 (en) 1992-05-22 2011-05-24 Arcimboldo Ab Removing dental plaque with krill enzymes
US6379654B1 (en) 2000-10-27 2002-04-30 Colgate Palmolive Company Oral composition providing enhanced tooth stain removal
US20050186526A1 (en) * 2002-11-01 2005-08-25 Bas Medical, Inc. Methods and systems for enabling and stabilizing tooth movement
EP1600141B1 (en) * 2004-05-24 2013-04-17 3M Deutschland GmbH Collagenolytic active enzyme containing compositions for the treatment of dental caries
US7811560B2 (en) 2006-01-30 2010-10-12 Auxilium Us Holdings, Llc Compositions and methods for treating collagen-mediated diseases
EP1844727A1 (en) * 2006-04-12 2007-10-17 3M Innovative Properties Company Dental instrument for removing solely unremineralisable carious dentin
US8454362B2 (en) * 2006-10-16 2013-06-04 Natural Dental Implants Ag Customized dental prosthesis for periodontal- or osseointegration, and related systems and methods
WO2008100833A2 (en) * 2007-02-13 2008-08-21 Auxilium International Holdings, Inc. Production of recombinant collagenases colg and colh in escherichia coli
US20090098509A1 (en) * 2007-10-15 2009-04-16 Arthur Kitchings Weathers Dental tooth extraction implement and method thereof
US20090181342A1 (en) * 2008-01-15 2009-07-16 Hua-Hong Chien Tooth Extration Assisting Device
US20100061972A1 (en) 2008-08-19 2010-03-11 Auxilium US Holdings,LLC Method of Treating Peyronie's Disease
US20120045816A1 (en) 2008-09-09 2012-02-23 Sialix, Inc. Novel Glycosylated Polypeptides
US20130166040A1 (en) * 2010-06-24 2013-06-27 The Board Of Trustee Of The University Of Illinois Reagents and methods for preparing teeth for implantation
AU2011322482B2 (en) 2010-10-30 2017-03-23 Oxford University Innovation Limited Treatment for Dupuytren's disease
WO2012125948A1 (en) 2011-03-16 2012-09-20 Biospecifics Technologies Corp. Compositions and methods for producing clostridial collagenases
PT3581199T (pt) 2011-10-21 2023-08-31 Endo Global Ventures Métodos de tratamento ou redução de paniculopatia edematosa fibroesclerótica
EP2852403B1 (en) * 2012-04-30 2018-03-07 Elastomics AB Methods for modification of tissues
WO2015140802A2 (en) * 2014-03-20 2015-09-24 Technion Research & Development Foundation Limited Delivery system comprising a proteolytic enzyme or effector thereof for use in a method for oral treatment and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3719367A1 (de) * 1987-06-10 1988-12-29 Duncker Martin Dr Verwendung von den stoffwechsel und/oder die struktureigenschaften von kollagen beeinflussenden wirksubstanzen in der kieferorthopaedie
WO2004041106A1 (en) * 2002-11-01 2004-05-21 Bas Medical, Inc. Methods and systems for enabling and stabilizing tooth movement

Also Published As

Publication number Publication date
WO2013164822A1 (en) 2013-11-07
IL235435B (en) 2018-10-31
EP2844276A1 (en) 2015-03-11
US20150050617A1 (en) 2015-02-19
EP2844276B1 (en) 2019-10-02
US10016492B2 (en) 2018-07-10
JP2015521169A (ja) 2015-07-27
AU2013255400A1 (en) 2014-12-04
EP2844276A4 (en) 2015-12-16
IN2014MN02422A (enExample) 2015-08-14
BR112014027347A2 (pt) 2017-06-27
CN104271152A (zh) 2015-01-07
CA2872227A1 (en) 2013-11-07

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