CN104257773B - A kind of oral drugs treating ankylosing spondylitis - Google Patents

A kind of oral drugs treating ankylosing spondylitis Download PDF

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CN104257773B
CN104257773B CN201410569176.9A CN201410569176A CN104257773B CN 104257773 B CN104257773 B CN 104257773B CN 201410569176 A CN201410569176 A CN 201410569176A CN 104257773 B CN104257773 B CN 104257773B
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ankylosing spondylitis
oral drugs
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CN104257773A (en
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陈沂芳
孙乐津
陈翠平
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Abstract

The present invention relates to a kind of Chinese medicine and preparation method thereof, especially a kind of oral drugs treating ankylosing spondylitis. It is smalls altogether by Carapax Et Plastrum Testudinis (processed), Fructus Psoraleae, Herba Epimedii, Radix Achyranthis Bidentatae, Colla cornus cervi, Flos Carthami, Ramulus Euonymi, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Radix Gentianae Macrophyllae, Radix Glycyrrhizae Preparata, warm boiled water. This method feature includes: treating both the principal and secondary aspects of a disease, safety is high, side effect is little, curative effect is reliable, and patient is acceptant. These oral drugs give full play to the pharmacological action of various composition, serve the kidney invigorating and superintend and direct by force, and effect of the logical stagnation pain of blood stasis dispelling, treating both the principal and secondary aspects of a disease, good effect, instant effect, composition are few, preparation is simple.

Description

A kind of oral drugs treating ankylosing spondylitis
Technical field
The present invention relates to a kind of extract oral medicine, especially a kind of oral drugs treating ankylosing spondylitis.
Background technology
Ankylosing spondylitis belongs to the categories such as Chinese medicine " numbness ", " rheumatism involving the bone ", " BI-syndrome involved the kidney ", " governor vessel sick ", is a kind of aggressive inflammation, morbidity slowly, state of an illness length and rise and fall, often involve bones of the body bone joint. The traditional Chinese medical science thinks that its pathogenesis is kidney yang deficiency, and the governor vessel stasis of blood is stagnant. Control suitable warming the kidney to activate YANG, superintend and direct by force dredging collateral. Current pathogeny is unclear, but generally believes there is height correlation with heredity, wound, inhabitation humidity and intestinal infection. The medicine universality of existing treatment ankylosing spondylitis is poor, often specific crowd is had certain curative effect, and other crowd then DeGrain is even completely ineffective. Chinese patent 2012102752259 discloses one " treatment ankylosing spondylitis medicine for external use and preparation method thereof ", by Radix Dipsaci, Rhizoma Cibotii, Herba Epimedii, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, Ramulus Cinnamomi, Rhizoma Drynariae, raw Radix Rehmanniae Preparata, the red Radix Paeoniae Alba, Semen Coicis, Herba Lycopodii, Bombyx Batryticatus, Qiang's Radix Angelicae Pubescentis, Radix Saposhnikoviae, Radix Achyranthis Bidentatae reasonable compatibility, special preparation method is adopted the mixing of each components in certain proportion to be prepared, this medication effect is pretty good, but composition is more, process for preparation is loaded down with trivial details, takes effect slow.
Summary of the invention
It is an object of the invention to provide a kind for the treatment of both the principal and secondary aspects of a disease, good effect, instant effect, composition is few, prepare the simple oral drugs treating ankylosing spondylitis.
The oral drugs for the treatment of ankylosing spondylitis of the present invention, are made up of the composition of following parts by weight: Carapax Et Plastrum Testudinis (processed) 10-15, Fructus Psoraleae 15-20, Herba Epimedii 10-15, Radix Achyranthis Bidentatae 15-20, Colla cornus cervi 9-12, Flos Carthami 10-12, Ramulus Euonymi 15-20, Radix Angelicae Sinensis 12-14, Radix Paeoniae Rubra 15-20, Radix Gentianae Macrophyllae 6-8, Radix Glycyrrhizae Preparata 6-8.
Wherein also has the composition of following parts by weight: sodium chloride particle 2-5.
As a further improvement on the present invention, the oral drugs of described treatment ankylosing spondylitis are made up of the composition of following parts by weight: Carapax Et Plastrum Testudinis (processed) 10, Fructus Psoraleae 15, Herba Epimedii 10, Radix Achyranthis Bidentatae 15, Colla cornus cervi 9, Flos Carthami 10, Ramulus Euonymi 15, Radix Angelicae Sinensis 12, Radix Paeoniae Rubra 15, Radix Gentianae Macrophyllae 6, Radix Glycyrrhizae Preparata 6, sodium chloride particle 2.
As a further improvement on the present invention, the oral drugs of described treatment ankylosing spondylitis are made up of the composition of following parts by weight: Carapax Et Plastrum Testudinis (processed) 15, Fructus Psoraleae 20, Herba Epimedii 15, Radix Achyranthis Bidentatae 20, Colla cornus cervi 12, Flos Carthami 12, Ramulus Euonymi 20, Radix Angelicae Sinensis 14, Radix Paeoniae Rubra 20, Radix Gentianae Macrophyllae 8, Radix Glycyrrhizae Preparata 8, sodium chloride particle 5.
As a further improvement on the present invention, the oral drugs of described treatment ankylosing spondylitis are made up of the composition of following parts by weight: Carapax Et Plastrum Testudinis (processed) 12, Fructus Psoraleae 18, Herba Epimedii 13, Radix Achyranthis Bidentatae 18, Colla cornus cervi 10, Flos Carthami 11, Ramulus Euonymi 18, Radix Angelicae Sinensis 12, Radix Paeoniae Rubra 17, Radix Gentianae Macrophyllae 7, Radix Glycyrrhizae Preparata 7, sodium chloride particle 3.
Carapax Et Plastrum Testudinis (processed): Carapax et Plastrum Testudinis refers to raw tortoise plastron, cleans for crude drug and dries, smash the person of being used as medicine to pieces. Clean Carapax et Plastrum Testudinis sheet sand parching to brown, immerses while hot in vinegar, dries, after rinsing with clear water, the person of being used as medicine and be Carapax Et Plastrum Testudinis (processed), be again vinegar Carapax et Plastrum Testudinis. There is effect of nourishing kidney YANG hyperactivity suppressing, replenishing kidney and strengthening bone, reinforcing the heart of nourishing blood. Cure mainly: hyperactivity of YANG due to deficiency of YIN, yin asthenia generating intrinsic heat, stirring-up of pathogenic wind in the interior resulting from deficiency, the atrophic debility of bones of suffering from a deficiency of the kidney, infantile metopism. deficiency of YIN-blood, palpitation with fear insomnia, forgetful.
Fructus Psoraleae: have another name called Fructus Psoraleae, the solid fat of mother-in-law, recklessly Semen Allii Tuberosi. Belong to Rosales, the annual upright draft of pulse family. Seed is used as medicine, and has the function of kidney invigorating and YANG supporting, spleen reinforcing stomach invigorating, and can control the dermatosiss such as psoriasis.
Herba Epimedii: for the dried leaves of Berberidaceae plant Herba Epimedii, Epimedium sagittatum, E. Pubescens or Herba Epimedii. Summer, autumn stem and leaf luxuriant time tap, remove stem, thick stalk and impurity, dry or dry in the shade. Chinese medicine thinks Herba Epimedii acrid-sweet flavor, temperature have effect of kidney invigorating and YANG supporting, expelling wind and removing dampness. Herba Epimedii stem and leaf contains icariine and volatile oil. Verified, Herba Epimedii has the effect of androgen sample, and its effect is better than Gecko and Hippocampus. Meanwhile, Herba Epimedii can also suppress vasomotor center, expands peripheral vessels, makes blood pressure drops, and can antitussive, eliminate the phlegm, relieving asthma, poliovirus, Staphylococcus albus, staphylococcus aureus etc. are also had significant inhibitory action.
Radix Achyranthis Bidentatae: also known as Radix Achyranthis Bidentatae, gains the name because originating in celebrating mansion, historical bosom. Dry root for amaranthaceous plant Radix Achyranthis Bidentatae. For conventional dispel-wind drug and blood circulation and stasis-eliminating medicine. Its bitter in the mouth; Acid; Property is put down. Cure mainly soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood, dysmenorrhea, puerperal abdominal pain due to blood stasis, note of the ancient Chinese abdominal mass, retention of placenta, pyretic stranguria, stranguria with blood, traumatic injury, carbuncle malignant boil, laryngopharynx swelling and pain etc.
Colla cornus cervi: inspissate the solid gum of contracting for Cornu Cervi decocting. Function: warming and recuperating the kidney-YANG, benefit essence are enriched blood, stopped blooding. Suitable in kidney yang deficiency, damage of essence blood deficiency, asthenia is won thin, and the multiple disease of losing blood of deficient cold type.
Flos Carthami: call red blue flower, thorn Flos Carthami, Compositae, Flos Carthami platymiscium, dry tubular flower, have special fragrance, mildly bitter flavor. Can stimulate the menstrual flow, invigorate blood circulation.
Ramulus Euonymi: make again winged euonymus, ghost arrow, June insult, four sides cutting edge of a knife or a sword, castor dustpan bavin, four rib trees, Gallus jabouillei strip, on four sides halberd, JIANZHONGXIAO, anaesthetic. The branch of tool fin or aliform appurtenance for Celastraceae plant winged euonymus. The whole year can adopt, and after extracting branch, removes twig and leaf, dries. Or collect its fin, dry. Removing blood stasis is had to stimulate the menstrual flow; Removing toxic substances and promoting subsidence of swelling; Effect of parasite killing.
Radix Angelicae Sinensis: call dry return, the Qin which, western Radix Angelicae Sinensis, Min Radix Angelicae Sinensis, Radix Angelicae Sinensis, Radix Angelicae Sinensis body, contain that Radix Angelicae Sinensis, Radix Angelicae Sinensis be bent, Radix Angelicae Gigatis, it is herbaceos perennial, and its root can be used as medicine, and is one of the most frequently used Chinese medicine.Benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation. For blood deficiency, shallow complexion, dizziness cardiopalmus.
Radix Paeoniae Rubra: for the dry root of ranunculaceae plant Radix Paeoniae. Radix Paeoniae opens red colored person, for Radix Paeoniae Rubra. Abnormal smells from the patient hardship is put down, nontoxic. Curing mainly pathogen stomachache, except arthralgia due to stagnation of blood, broken heavily fortified point is long-pending, and cold and heat are sick tired, pain relieving, diuresis, QI invigorating.
Radix Gentianae Macrophyllae: another name: gentiana macrophylla, Gentiana macrophylla Pall., RADIX GENTIANAE MACROPHYLLAE. Herbaceos perennial, root is used as medicine, and is one of principal agents of disease such as treatment rheumatic arthritis, tuberculosis, hectic fever, jaundice.
Radix Glycyrrhizae Preparata: be leguminous plant, Radix Glycyrrhizae Preparata is the Radix Glycyrrhizae baked with honey, is commonly called as the process of preparing Chinese medicine, it is simply that put by Mel in pot and be smelt middle honey, uses slow fire instead and adds Radix Glycyrrhizae sheet and stir uniformly, puts barn or taking-up when baking oven is dried to tack-free, cools. Zhigancao decoction has benefiting qi and nourishing yin, and activate yang multiple arteries and veins therapeutic efficiency.
Sodium chloride: outward appearance is white crystalline, its source mainly in the seawater, is the main component of Sal. Sodium chloride is that people institute is indispensable. In adult body, the total amount of contained sodium ion is about 60 grams, and wherein 80% is present in extracellular fluid, namely in blood plasma and intercellular fluid. Chloride ion is also primarily present in extracellular fluid. The physiological function of sodium ion and chloride ion mainly has: maintain the osmotic pressure of extracellular fluid; Participate in the adjustment of internal acid-base balance; Chloride ion participates in the generation of gastric acid in vivo, additionally, sodium chloride also has effect on the NE maintaining N&M.
Above-mentioned various compositions are organically combined by the oral drugs of this treatment ankylosing spondylitis, give full play to the pharmacological action of various composition, serve the kidney invigorating and superintend and direct by force, effect of the logical stagnation pain of blood stasis dispelling, the method treating both the principal and secondary aspects of a disease, good effect, instant effect, composition are few, preparation is simple. Selecting for 100 example ages in 12-70 year patient clinical contrast test, one course for the treatment of of medication, effective is 75 examples, is effectively 25 examples; After two courses for the treatment of of medication, effective is 95 examples, is effectively 5 examples.
Detailed description of the invention
Embodiment 1:
A kind of oral drugs treating ankylosing spondylitis of the present invention, are made up of the composition of following parts by weight: Carapax Et Plastrum Testudinis (processed) 10, Fructus Psoraleae 15, Herba Epimedii 10, Radix Achyranthis Bidentatae 15, Colla cornus cervi 9, Flos Carthami 10, Ramulus Euonymi 15, Radix Angelicae Sinensis 12, Radix Paeoniae Rubra 15, Radix Gentianae Macrophyllae 6, Radix Glycyrrhizae Preparata 6.
It is smalls altogether by above-mentioned each composition, each consumption 6-8 gram, about 50 100 milliliters of warm boiled waters, every day 2 times. It within 30 days, it is a course for the treatment of.
Certain man, 42 years old, instrument workman. Suffer from ankylosing spondylitis 11 years, since idiopathy, take the anti-inflammatory analgesic medicine such as nonsteroidal, sulfasalazine and Chinese medicine always, though non-intermittent treatment, but still lumbar and back pain, morning is stiff, night stands up difficulty, movable function is limited can not adhere to that work is examined. In addition patient is with neck stiffness, and thorax tension force is limited, and low grade fever shape is thin, and soreness of the waist and knees is had a dizzy spell, Hiccough and deaf, aversion to cold and cold limbs, pale complexion, the slightly red white and thin fur of the little matter of tongue, deep-thready pulse. Tcm diagnosis is deficiency of the liver and kidney ankylosing spondylitis, adopts the oral drugs for the treatment of ankylosing spondylitis of the present invention, and after taking two courses for the treatment of continuously, all diseases are taken a turn for the better, and can adhere to working work. It is advised to continue to take medicine to attack solid curative effect.
Embodiment 2:
A kind of oral drugs treating ankylosing spondylitis of the present invention, are made up of the composition of following parts by weight: Carapax Et Plastrum Testudinis (processed) 10, Fructus Psoraleae 15, Herba Epimedii 10, Radix Achyranthis Bidentatae 15, Colla cornus cervi 9, Flos Carthami 10, Ramulus Euonymi 15, Radix Angelicae Sinensis 12, Radix Paeoniae Rubra 15, Radix Gentianae Macrophyllae 6, Radix Glycyrrhizae Preparata 6, sodium chloride particle 2.
Instructions of taking is with embodiment 1.
Embodiment 3:
A kind of oral drugs treating ankylosing spondylitis of the present invention, are made up of the composition of following parts by weight: Carapax Et Plastrum Testudinis (processed) 15, Fructus Psoraleae 20, Herba Epimedii 15, Radix Achyranthis Bidentatae 20, Colla cornus cervi 12, Flos Carthami 12, Ramulus Euonymi 20, Radix Angelicae Sinensis 14, Radix Paeoniae Rubra 20, Radix Gentianae Macrophyllae 8, Radix Glycyrrhizae Preparata 8, sodium chloride particle 5.
Instructions of taking is with embodiment 1.
Embodiment 4:
A kind of oral drugs treating ankylosing spondylitis of the present invention, are made up of the composition of following parts by weight: Carapax Et Plastrum Testudinis (processed) 12, Fructus Psoraleae 18, Herba Epimedii 13, Radix Achyranthis Bidentatae 18, Colla cornus cervi 10, Flos Carthami 11, Ramulus Euonymi 18, Radix Angelicae Sinensis 12, Radix Paeoniae Rubra 17, Radix Gentianae Macrophyllae 7, Radix Glycyrrhizae Preparata 7, sodium chloride particle 3.

Claims (4)

1. the oral drugs treating ankylosing spondylitis, it is characterised in that be made up of the composition of following parts by weight: Carapax Et Plastrum Testudinis (processed) 10-15, Fructus Psoraleae 15-20, Herba Epimedii 10-15, Radix Achyranthis Bidentatae 15-20, Colla cornus cervi 9-12, Flos Carthami 10-12, Ramulus Euonymi 15-20, Radix Angelicae Sinensis 12-14, Radix Paeoniae Rubra 15-20, Radix Gentianae Macrophyllae 6-8, Radix Glycyrrhizae Preparata 6-8, sodium chloride particle 2-5.
2. a kind of oral drugs treating ankylosing spondylitis according to claim 1, it is characterised in that be made up of the composition of following parts by weight: Carapax Et Plastrum Testudinis (processed) 10, Fructus Psoraleae 15, Herba Epimedii 10, Radix Achyranthis Bidentatae 15, Colla cornus cervi 9, Flos Carthami 10, Ramulus Euonymi 15, Radix Angelicae Sinensis 12, Radix Paeoniae Rubra 15, Radix Gentianae Macrophyllae 6, Radix Glycyrrhizae Preparata 6, sodium chloride particle 2.
3. a kind of oral drugs treating ankylosing spondylitis according to claim 1, it is characterised in that be made up of the composition of following parts by weight: Carapax Et Plastrum Testudinis (processed) 15, Fructus Psoraleae 20, Herba Epimedii 15, Radix Achyranthis Bidentatae 20, Colla cornus cervi 12, Flos Carthami 12, Ramulus Euonymi 20, Radix Angelicae Sinensis 14, Radix Paeoniae Rubra 20, Radix Gentianae Macrophyllae 8, Radix Glycyrrhizae Preparata 8, sodium chloride particle 5.
4. a kind of oral drugs treating ankylosing spondylitis according to claim 1, it is characterised in that be made up of the composition of following parts by weight: Carapax Et Plastrum Testudinis (processed) 12, Fructus Psoraleae 18, Herba Epimedii 13, Radix Achyranthis Bidentatae 18, Colla cornus cervi 10, Flos Carthami 11, Ramulus Euonymi 18, Radix Angelicae Sinensis 12, Radix Paeoniae Rubra 17, Radix Gentianae Macrophyllae 7, Radix Glycyrrhizae Preparata 7, sodium chloride particle 3.
CN201410569176.9A 2014-10-23 2014-10-23 A kind of oral drugs treating ankylosing spondylitis Expired - Fee Related CN104257773B (en)

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