CN104224827A - Preparation method of composition for improving growth and development and assisting in memory improvement - Google Patents

Abstract

The invention relates to a preparation method of a composition for improving growth and development and assisting in memory improvement. In every 100 g of the composition, main materials include 7.5 g of lysine, 2 g of taurine, 23.2 mg of retinol, 44 mg of thiamine, 46 mg of cholecalciferol, 60 mu g of riboflavin, 1g of DHA, 12.5 mg of folate, 465 mg of zinc gluconate, 835 mg of ferrous gluconate, and 45 g of calcium carbonate; and in every 100 g of the composition, auxiliary materials include 11 g of milk powder, 12.3 g of sucrose, 5 g of yeast, 10 mg of lemon yellow, 2.5 g of a citric acid, 1 g of magnesium stearate, 0.25 g of stevioside, and the balance of starch. The preparation method comprises the following processing steps: A, weighting the raw materials according to a formula, respectively crushing the raw materials by using a universal crusher, and enabling the obtained materials to pass through an 80-mesh sieve to a crushed product for later use; B, mixing; C, preparing an adhesive; D, granulating; E, drying; F, straightening granules; and G, tabletting. The composition prepared by the preparation method disclosed by the invention can combine the nutritional values of the main raw materials well, and trace elements in the composition are unlikely to be destroyed by the outside, so that through granulating, the composition can be easily taken by children, the fishy smell in the DHA is masked more easily, and the composition is absorbed by gastrointestinal tracts more easily.

Description

A kind of preparation method of compositions improving growth promoter, auxiliary improvement of memory

Technical field

The present invention relates to the production method of Pharmaceutical composition, particularly a kind of preparation method of compositions improving growth promoter, auxiliary improvement of memory.

Background technology

Healthy and clever is the problem of the head of a family to special concern in child's growth and development process, and along with society, economic develop rapidly, the teen-age growth promoter of Chinese children and health level are greatly improved.Anthropometic increases significantly, 7 to 17 years old children and youth height average increasing amounts between 20 years, and male and female students reaches 6.9 centimetres and 5.5 centimetres respectively; Body weight increases more swift and violent, and male and female students reaches 6.6 kilograms and 4.5 kilograms respectively.Along with the raising of children and youth health circularity, " Semen Phaseoli radiati Germinatus " build obviously reduces, and outstanding behaviours is that growth amplitude is surged, and impels Development in Puberty and sexual development age constantly to shift to an earlier date.Expert thinks and the teen-age trophophase trend of Chinese children in speed, has exceeded the Acceleration of growth level that each developed country occurs after World War II.

Although present good trend generally, no matter still have indivedual children due to congenital factors or posteriori bad habit, cause the problem of growth retardation and memory ability deficiency, be to child, or be all very large puzzlement to family.

Summary of the invention

The object of the present invention is to provide a kind of preparation method of compositions improving growth promoter, auxiliary improvement of memory, it solves above-mentioned technical problem of the prior art, can be good at the nutritive value in conjunction with above-mentioned primary raw material, trace element wherein should not by external world, granulation can so that child takes, more easily cover the fishy smell in its DHA, more easily allow gastrointestinal tract.

For solving the problems of the technologies described above, the present invention is achieved in that

A kind of preparation method of compositions improving growth promoter, auxiliary improvement of memory, it is characterized in that: in the compositions of every 100 grams, major ingredient is lysine 7.5g, taurine 2g, retinol 23.2mg, thiamine 44mg, cholecalciferol 46mg, riboflavin 60ug, DHA 1g, folic acid 12.5mg, zinc gluconate 465 mg, Ferrous gluconate 835 mg, calcium carbonate 45g, in the compositions of every 100 grams, adjuvant is milk powder 11g, sucrose 12.3g, yeast 5g, lemon yellow 10mg, citric acid 2.5g, magnesium stearate 1g, stevioside 0.25g, starch surplus; Its step of preparation process is:

A takes lysine by formula ratio, taurine, retinol, thiamine, gallbladder calcium solidification alcohol, riboflavin, DHA, folic acid, zinc gluconate, Ferrous gluconate, calcium carbonate, yeast, starch, stevioside, milk powder, citric acid Universalpulverizer are pulverized clearly, cross 80 orders, for subsequent use;

B mixes: above-mentioned each fine powder is put abundant mix homogeneously in mixer;

C binding agent is prepared: be dissolved in by sucrose in suitable quantity of water, filters, obtains 60% syrup for subsequent use;

D granulates: lemon yellow is dissolved in suitable quantity of water, pours above-mentioned syrup mix homogeneously into, then mix with the mixed powder of supplementary material, make soft material, with the wet grain of granulation mechanism, crosses 18 mesh sieves;

E is dry: be spread out in dish by above-mentioned wet granular, oven drying; Note in dry run often turning over, prevent particle from caking, baking temperature 60 DEG C, drying time 4H;

F granulate: cross 16 mesh sieve granulate with pelletizing machine, add magnesium stearate lubricant, each dish granule mix homogeneously;

G tabletting: by the granule tabletting machine of mixing, the heavy 1.0g of every sheet.

The advantage of the inventive method is:

1, preparation method of the present invention, can be good at the nutritive value in conjunction with above-mentioned primary raw material, and trace element wherein should not by external world, and granulation so that child takes, can more easily cover the fishy smell in its DHA, more easily allows gastrointestinal tract.

2, the product prepared by the inventive method has the effect improving growth promoter, auxiliary improvement of memory, is applicable to retarded growth, needs the children of Improving memory.

Detailed description of the invention

The invention discloses a kind of preparation method of compositions improving growth promoter, auxiliary improvement of memory, in the compositions of every 100 grams, major ingredient is lysine 7.5g, taurine 2g, retinol 23.2mg, thiamine 44mg, cholecalciferol 46mg, riboflavin 60ug, DHA 1g, folic acid 12.5mg, zinc gluconate 465 mg, Ferrous gluconate 835 mg, calcium carbonate 45g, and in the compositions of every 100 grams, adjuvant is milk powder 11g, sucrose 12.3g, yeast 5g, lemon yellow 10mg, citric acid 2.5g, magnesium stearate 1g, stevioside 0.25g, starch surplus; Its step of preparation process is:

A, to take lysine by formula ratio, taurine, retinol, thiamine, gallbladder calcium solidification alcohol, riboflavin, DHA, folic acid, zinc gluconate, Ferrous gluconate, calcium carbonate, yeast, starch, stevioside, milk powder, citric acid Universalpulverizer pulverize clearly, cross 80 orders, for subsequent use;

B, mixing: above-mentioned each fine powder is put abundant mix homogeneously in mixer;

C, binding agent are prepared: be dissolved in by sucrose in suitable quantity of water, filter, obtain 60% syrup for subsequent use;

D, granulation: lemon yellow is dissolved in suitable quantity of water, pour above-mentioned syrup mix homogeneously into, then mix with the mixed powder of supplementary material, make soft material, with the wet grain of granulation mechanism, crosses 18 mesh sieves;

E, drying: above-mentioned wet granular is spread out in dish, oven drying.Note in dry run often turning over, prevent particle from caking, baking temperature 60 DEG C, drying time 4H;

F, granulate: cross 16 mesh sieve granulate with pelletizing machine, add magnesium stearate lubricant, each dish granule mix homogeneously;

G, tabletting: by the granule tabletting machine of mixing, the heavy 1.0g of every sheet.

After above-mentioned steps terminates, can further include following steps:

H, inherent quality are examined entirely, qualified rear loading polyolefin plastics bottle.

I, external quality are examined entirely, qualified rear vanning (corrugated paper) warehouse-in.Put dry shady and cool place to preserve.

J, warehouse-in, put dry shady and cool place and preserve.

The cleanliness factor of K, 1 ~ 8 production environment is 100,000 grades.

Also it is significant to note that the quality examination of raw material in the present invention:

1, require that material quality is excellent, health, pesticide, chemical substance, poisonous metal and radioactive material contamination must not be subject to, must not containing harmful toxin.

2, raw and auxiliary material buying strict implement has key standard, should have the qualified certificate of the sanitary inspection in sourcing or the place of production.

3, the quality testing report of workshop examination & verification often kind of raw material, can be for the production of when confirming to meet quality standard.

Be only preferred embodiment of the present invention in sum, be not used for limiting practical range of the present invention.Namely all equivalences done according to the content of the present patent application the scope of the claims change and modify, and all should be technology category of the present invention.

Claims (1)

1. one kind is improved the preparation method of compositions of growth promoter, auxiliary improvement of memory, it is characterized in that: in the compositions of every 100 grams, major ingredient is lysine 7.5g, taurine 2g, retinol 23.2mg, thiamine 44mg, cholecalciferol 46mg, riboflavin 60ug, DHA 1g, folic acid 12.5mg, zinc gluconate 465 mg, Ferrous gluconate 835 mg, calcium carbonate 45g, in the compositions of every 100 grams, adjuvant is milk powder 11g, sucrose 12.3g, yeast 5g, lemon yellow 10mg, citric acid 2.5g, magnesium stearate 1g, stevioside 0.25g, starch surplus; Its step of preparation process is:

A takes lysine by formula ratio, taurine, retinol, thiamine, gallbladder calcium solidification alcohol, riboflavin, DHA, folic acid, zinc gluconate, Ferrous gluconate, calcium carbonate, yeast, starch, stevioside, milk powder, citric acid Universalpulverizer are pulverized clearly, cross 80 orders, for subsequent use;

B mixes: above-mentioned each fine powder is put abundant mix homogeneously in mixer;

C binding agent is prepared: be dissolved in by sucrose in suitable quantity of water, filters, obtains 60% syrup for subsequent use;

D granulates: lemon yellow is dissolved in suitable quantity of water, pours above-mentioned syrup mix homogeneously into, then mix with the mixed powder of supplementary material, make soft material, with the wet grain of granulation mechanism, crosses 18 mesh sieves;

E is dry: be spread out in dish by above-mentioned wet granular, oven drying; Note in dry run often turning over, prevent particle from caking, baking temperature 60 DEG C, drying time 4H;

F granulate: cross 16 mesh sieve granulate with pelletizing machine, add magnesium stearate lubricant, each dish granule mix homogeneously;

G tabletting: by the granule tabletting machine of mixing, the heavy 1.0g of every sheet.