CN104224434A - Tumor therapeutic apparatus with precise temperature control - Google Patents
Tumor therapeutic apparatus with precise temperature control Download PDFInfo
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- CN104224434A CN104224434A CN201410558448.5A CN201410558448A CN104224434A CN 104224434 A CN104224434 A CN 104224434A CN 201410558448 A CN201410558448 A CN 201410558448A CN 104224434 A CN104224434 A CN 104224434A
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- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 90
- 230000001225 therapeutic effect Effects 0.000 title abstract description 5
- 238000010438 heat treatment Methods 0.000 claims abstract description 26
- 238000012545 processing Methods 0.000 claims abstract description 24
- 238000006243 chemical reaction Methods 0.000 claims abstract description 15
- 238000002560 therapeutic procedure Methods 0.000 claims description 35
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 29
- 229910052697 platinum Inorganic materials 0.000 claims description 15
- 239000004020 conductor Substances 0.000 claims description 12
- 238000010586 diagram Methods 0.000 description 8
- 238000000034 method Methods 0.000 description 7
- 239000000523 sample Substances 0.000 description 6
- 238000012544 monitoring process Methods 0.000 description 4
- 238000013461 design Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000002513 implantation Methods 0.000 description 3
- 238000000015 thermotherapy Methods 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000009529 body temperature measurement Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000001613 neoplastic effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 210000004881 tumor cell Anatomy 0.000 description 1
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- Thermotherapy And Cooling Therapy Devices (AREA)
Abstract
The invention relates to a tumor therapeutic apparatus with precise temperature control. The tumor therapeutic apparatus comprises a data processing control unit with a touch display screen, multiple A/D conversion circuit units, a PID temperature control system, multiple temperature measuring sensors (2) and multiple temperature-controllable heaters (1). The output ends of the temperature measuring sensors (2) are connected with the input end of the data processing control unit with the touch display screen through the A/D conversion circuit units respectively. The temperature measuring output ends of the temperature-controllable heaters (1) are connected with the input end of the PID temperature control system through the A/D conversion circuit units respectively. The tumor therapeutic apparatus with precise temperature control can completely kill tumor tissue under an ideal temperature, and due to the fact that the heating temperature can be precisely controlled, normal human biological tissue can not be hurt.
Description
Technical field
The present patent application is November 10 2010 applying date, and application number is: 201010537185.1, the divisional application of the application for a patent for invention that name is called " accurate temperature control tumor therapy instrument and control method thereof ".The present invention relates to a kind of apparats for treating tumor, especially relate to a kind of therapeutic instrument of thermally treating tumor.
Background technology
Medical circle is generally acknowledged: tumor cell will be dead when 42.5 DEG C of being heated to, and when normal tissue is heated to 45 DEG C-47 DEG C, just can lose function of organization.Therefore medical circle adopts neoplastic fevers therapy widely to use as a kind of method for the treatment of tumor.Therapeutic Method is ideally: should guarantee that whole tumor tissues is heated to 42.5 DEG C and keeps a period of time on the one hand; On the other hand, ensure that normal structure can not be heated to more than 45 DEG C, in order to avoid the normal function of injury human body.But apparats for treating tumor in the market does not have accurate thermometric and temperature controlling function.
Reverse temperature control combined probe type tumor thermal-therapeutic apparatus patent (application number 201010134281.1) is although disclose a kind of temperature control probe, and it exists following technological deficiency:
(1) although it is called " reverse temperature control combined probe type tumor thermal-therapeutic apparatus ", it disclose only the heating stylus of a kind of probe, and can not be referred to as tumor thermal-therapeutic apparatus.
(2) it is not owing to disclosing any attemperating unit, and thus cannot realize tumor tissues can be guaranteed to be in the temperature value of a setting or 42.5 DEG C always, and heating-up temperature is the basis of tumor thermotherapy accurately.As shown in Figure 1, tumor tissues heating process there will be temperature overshot effect, if adopt Artificial Control, will cause heating-up temperature fluctuating up and down in a big way at predetermined value or ideal value (42.5 DEG C), cannot equilibrium temperature.So will badly influence the effect for the treatment of, even can damage normal tissue and organ, the object of oncotherapy cannot be reached.
Summary of the invention
The present invention devises a kind of accurate temperature control tumor therapy instrument, and its technical problem solved is:
(1) the hot mode apparats for treating tumor in existing clinical medicine field does not have the function of thermometric and temperature control.
(2) the hot mode apparats for treating tumor in existing clinical medicine field does not have the function of accurate temperature controlling.
(3) the probe heating stylus in reverse temperature control combined probe type tumor thermal-therapeutic apparatus patent application does not solve climate control issues.
In order to solve the technical problem of above-mentioned existence, present invention employs following scheme:
A kind of accurate temperature control tumor therapy instrument, comprise with the data processing control units of touch display screen, a plurality of A/D conversion circuit unit, PID temperature control system, a plurality of temperature transducer (2) and a plurality of temperature-controllable heater (1), the outfan of described a plurality of temperature transducer (2) is connected with the data processing control units input with touch screen respectively by A/D conversion circuit unit described in; The temperature survey outfan of a plurality of temperature-controllable heater (1) is connected with described PID temperature control system input respectively by A/D conversion circuit unit described in.
Further, described PID temperature control system comprises PID temperature control circuit unit and multiple solid-state relay, and the hot output terminal that adds of described PID control circuit unit is connected with the heating current input of temperature-controllable heater (1) described in each by described solid-state relay; The input of described PID temperature control circuit unit is connected by the temperature survey end of described A/D conversion circuit unit with each temperature-controllable heater (1).
Further, the described data processing control units with touch display screen is connected with an alarm unit.
Further, the described data processing control units with touch display screen is connected with described PID temperature control system, for setting and amendment pid parameter.
Further, described temperature transducer (2) comprises a platinum resistance (24), and described platinum resistance (24) connects temperature transducer positive wire (21), thermometric heat sensor working zero line (22) and thermometric heat sensor cathode conductor (23) at least respectively.
Further, described temperature-controllable heater (1) comprises heater (11) and temperature sensor (12), it is inner that described temperature sensor (12) is placed on heater (11), and described heater (11) two ends are connected with the positive wire (111) of temperature-controllable heater (1) heating current input and cathode conductor (112) respectively; Described temperature sensor (12) comprises a platinum resistance, and described platinum resistance connects temperature sensor positive wire (121), temperature sensor working zero line (122) and temperature sensor cathode conductor (123) at least respectively.
Control a method for accurate temperature control tumor therapy instrument, comprise the following steps:
First step: described a plurality of temperature-controllable heater (1) is implanted in tumor tissues (3) respectively, described a plurality of temperature transducer (2) is implanted in the region that described tumor tissues (3) has a common boundary with normal structure (4) respectively;
Second step: after opening accurate temperature control tumor therapy instrument power supply, described a plurality of temperature-controllable heater (1) is to described tumor tissues (3) continuous heating, and the temperature analog signal that a plurality of temperature transducer (2) and a plurality of temperature-controllable heater (1) gather is converted to digital signal by A/D converter and transfers to described PID temperature control circuit unit and the data processing control units with touch display screen; Described PID temperature control system and with the data processing control units of touch display screen by the heating and temperature control of each temperature-controllable heater (1) described in predetermined value or 42.5 DEG C;
Third step: after the measured temperature of a plurality of temperature transducers (2) being implanted in described tumor tissues (3) and described normal structure (4) juncture area also reaches predetermined value or 42.5 DEG C, the caloric value that all temperature-controllable heaters (1) export is only and maintains tumor tissues (3) and to be in needed for predetermined value or 42.5 DEG C and to continue one period of scheduled time for needed for tumor tissues (3).
Further, described alarm unit is when described accurate temperature control tumor therapy instrument work, Real-Time Monitoring is carried out to the temperature of each temperature-controllable heater (1), when the predetermined value set during the temperature signal that one or more described temperature-controllable heater (1) sends is higher than described data processing control units or 42.5 DEG C, will warning reminding doctor or patient, or when temperature-controllable heater or temperature transducer break down alarm.
This accurate temperature control tumor therapy instrument and control method thereof, compared with traditional thermotherapy apparats for treating tumor, have following beneficial effect:
(1) the present invention is owing to disclosing a kind of accurate temperature control tumor therapy instrument, this accurate temperature control tumor therapy instrument is fully killed tumor tissues under can be implemented in desirable temperature, simultaneously because temperature can accurately control thus also ensure to injure normal human biological tissue.
(2) the present invention is owing to being provided with PID temperature control system, and this PID temperature control system can guarantee that tumor tissues is heated to predetermined value or 42.5 DEG C by heater, avoids the phenomenon that in heating process, temperature fluctuation range is large simultaneously, achieves the object of accurate temperature controlling.
(3) the present invention is owing to being placed in the inside of heater by temperature sensor, the design of this structure can make temperature sensor more can react the real time temperature of heater really, Pt100 platinum resistance has well stable temperature resistance characteristic as temperature sensor simultaneously, therefore can realize heating and temperature control accurately.
(4) the present invention is owing to being provided with an alarm unit, and alarm unit, when accurate temperature control tumor therapy instrument works, carries out Real-Time Monitoring to the duty of each temperature-controllable heater, further ensures the safety in utilization of accurate temperature control tumor therapy instrument.
(5) the present invention is owing to adopting the data processing control units with touch display screen, makes the setting of accurate temperature control tumor therapy instrument running parameter (comprising time, temperature etc.) and the adjustment of pid control parameter, is accomplished by touch manner.The duty of all temperature transducers and temperature-controllable heater, shows all on a display screen simultaneously, and simple to operate, directly perceived.
Accompanying drawing explanation
Fig. 1 is the functional arrangement that tumor tissues heating process there will be overshoot effect;
Fig. 2 is the structural representation of temperature-controllable heater in the present invention;
Fig. 3 is the structural representation of temperature transducer in the present invention;
Fig. 4 is temperature-controllable heater and the first implantation schematic diagram of temperature transducer in the present invention;
Fig. 5 is temperature-controllable heater and temperature transducer the second implantation schematic diagram in the present invention;
Fig. 6 is temperature-controllable heater and the third implantation schematic diagram of temperature transducer in the present invention;
Fig. 7 is accurate temperature control tumor therapy instrument parts of the present invention composition schematic diagram;
Fig. 8 is temperature control procedure function schematic diagram in tumor tissues heating process in the present invention.
Description of reference numerals:
1-temperature-controllable heater; 11-heater; 111-positive wire; 112-cathode conductor; 12-temperature sensor; 121-temperature sensor positive wire; 122-temperature sensor working zero line; 123-temperature sensor cathode conductor;
2-temperature transducer; 21-temperature transducer positive wire; 22-thermometric heat sensor working zero line; 23-thermometric heat sensor cathode conductor; 24-platinum resistance;
3-tumor tissues; 4-normal structure.
Detailed description of the invention
Below in conjunction with Fig. 2 to Fig. 8, the present invention will be further described:
As shown in Figure 2, temperature-controllable heater 1 comprises heater 11 and temperature sensor 12, and it is inner that temperature sensor 12 is placed in heater 11; Heater 11 two ends are connected with the positive wire 111 of temperature-controllable heater 1 heating current input and cathode conductor 112 respectively; Temperature sensor 12 comprises a platinum resistance, and platinum resistance connects temperature sensor positive wire 121, temperature sensor working zero line 122 and temperature sensor cathode conductor 123 at least respectively.Temperature sensor adopts the object of three line connected modes, is to eliminate temperature-controllable heater to be connected the thermometric error that wire introduces with PID temperature control circuit unit, to ensure the control accuracy of heating-up temperature.PID temperature control is exactly that the control modes such as comprehensive ratio, integration, differential control heating process, to reach the heating process needed for treatment.
As shown in Figure 3, temperature transducer 2 comprises a platinum resistance 24, and platinum resistance 24 connects temperature transducer positive wire 21, thermometric heat sensor working zero line 22 and thermometric heat sensor cathode conductor 23 at least respectively.Temperature transducer adopts three line connected modes, is to be connected the thermometric error that wire introduces with the DATA REASONING control unit with touch display screen, to ensure temperature measurement accuracy to eliminate temperature transducer.
As shown in Figure 4, multiple temperature-controllable heater 1 and multiple temperature transducer 2 the first distribution schematic diagram on tumor tissues 3 and normal structure 4.Wherein, multiple temperature transducer 2 is distributed in region that tumor tissues 3 and normal structure 4 have a common boundary and is positioned at normal structure 4.Distribution like this can determine heating-up temperature and the heated condition of tumor tissues 3 accurately by temperature transducer 2.
As shown in Figure 5, multiple temperature-controllable heater 1 and the second distribution schematic diagram of multiple temperature transducer 2 on tumor tissues 3 and normal structure 4.Wherein, multiple temperature transducer 2 is distributed in region that tumor tissues 3 and normal structure 4 have a common boundary and is positioned at tumor tissues 3.Distribution like this also can determine heating-up temperature and the heated condition of tumor tissues 3 accurately by temperature transducer 2.
As shown in Figure 6, multiple temperature-controllable heater 1 and the second distribution schematic diagram of multiple temperature transducer 2 on tumor tissues 3 and normal structure 4.Wherein, multiple temperature transducer 2 is distributed on the region that tumor tissues 3 and normal structure 4 have a common boundary.Distribution like this also can determine heating-up temperature and the heated condition of tumor tissues 3 accurately by temperature transducer 2.
As described in Figure 7, a kind of accurate temperature control tumor therapy instrument, comprises with the data processing control units of touch display screen, a plurality of A/D conversion circuit unit, PID temperature control system, a plurality of temperature transducer 2 and a plurality of temperature-controllable heater 1; The outfan of a plurality of temperature transducer 2 is connected with the data processing control units input with touch screen respectively by an A/D conversion circuit unit; The temperature survey outfan of a plurality of temperature-controllable heater 1 is connected with PID temperature control system input respectively by an A/D conversion circuit unit.
PID temperature control system comprises PID temperature control circuit unit and multiple solid-state relay, and the hot output terminal that adds of PID control circuit unit is connected with the heating current input of each temperature-controllable heater 1 by solid-state relay; The input of PID temperature control circuit unit is connected with the temperature survey end of each temperature-controllable heater 1 by A/D conversion circuit unit.
Data processing control units with touch display screen is connected with an alarm unit.
Data processing control units with touch display screen is connected with described PID temperature control circuit unit, for setting and amendment pid parameter.
The parameter of required setting during accurate temperature control tumor therapy instrument work, is set by touch display screen.The Temperature numerical of accurate temperature control tumor therapy instrument, time service numerical value, pid parameter and other correlation values, touch display screen shows.
The operation principle of this accurate temperature control tumor therapy instrument is as follows:
First step: a plurality of temperature-controllable heater 1 is implanted in tumor tissues 3 respectively, a plurality of temperature transducer 2 is implanted in the region that described tumor tissues 3 has a common boundary with normal structure 4 respectively;
Second step: after opening accurate temperature control tumor therapy instrument power supply, tumor tissues 3 continuous heating given by a plurality of temperature-controllable heater 1, and the temperature analog signal that a plurality of temperature transducer 2 and a plurality of temperature-controllable heater 1 gather is converted to digital signal by A/D converter and transfers to PID temperature control circuit unit and the data processing control units with touch display screen; PID temperature control circuit unit and with the data processing control units of touch display screen by the heating and temperature control of each temperature-controllable heater 1 in predetermined value or 42.5 DEG C;
Third step: after the measuring tempeature value of a plurality of temperature transducers 2 being implanted in tumor tissues 3 and normal structure 4 juncture area also reaches predetermined value or 42.5 DEG C, the caloric value that all temperature-controllable heater 1 exports is only and maintains tumor tissues 3 and be in needed for predetermined value or 42.5 DEG C, and continues one period of scheduled time for needed for tumor tissues 3.
In addition, described alarm unit is when described accurate temperature control tumor therapy instrument work, Real-Time Monitoring is carried out to the temperature of each temperature-controllable heater 1, when the predetermined value set during the temperature signal that one or more described temperature-controllable heater 1 sends is higher than described data processing control units or 42.5 DEG C, will warning reminding doctor or patient, or when temperature-controllable heater or temperature transducer break down alarm.
As shown in Figure 8, owing to being provided with PID temperature control system, this PID temperature-controlling system can guarantee that tumor tissues is heated to predetermined value or 42.5 DEG C by heater, avoids the phenomenon that in heating process, temperature fluctuation range is large simultaneously, achieves the object of accurate temperature controlling.
This accurate temperature control tumor therapy instrument and control method thereof compared with traditional thermotherapy apparats for treating tumor, have following beneficial effect with thermometric heating sensor:
(1) the present invention is owing to disclosing a kind of accurate temperature control tumor therapy instrument, this accurate temperature control tumor therapy instrument is fully killed tumor tissues under can be implemented in desirable temperature, simultaneously because temperature can accurately control thus also ensure to injure normal human biological tissue.
(2) the present invention is owing to being provided with PID temperature control circuit unit, and this PID control temperature unit can guarantee that tumor tissues is heated to predetermined value or 42.5 DEG C by heater, avoids the phenomenon that in heating process, temperature fluctuation range is large simultaneously, achieves the object of accurate temperature controlling.
(3) the present invention is due to by the inside of temperature sensor as heater, the design of this structure can make temperature sensor more can react the real time temperature of heater really, Pt100 platinum resistance has well stable temperature resistance characteristic as temperature sensor simultaneously, therefore can realize heating and temperature control accurately.
(4) the present invention is owing to being provided with an alarm unit, and alarm unit, when accurate temperature control tumor therapy instrument works, carries out Real-Time Monitoring to the duty of each temperature-controllable heater, further ensures the safety in utilization of accurate temperature control tumor therapy instrument.
(5) the present invention is owing to adopting the data processing control units with touch display screen, makes the setting of accurate temperature control tumor therapy instrument running parameter (comprising time, temperature etc.) and the adjustment of pid control parameter, is accomplished by touch manner.The duty of all temperature transducers and temperature-controllable heater, shows all on a display screen simultaneously, and simple to operate, directly perceived.
Above by reference to the accompanying drawings to invention has been exemplary description; obvious realization of the present invention is not subject to the restrictions described above; as long as have employed the various improvement that method of the present invention is conceived and technical scheme is carried out; or design of the present invention and technical scheme directly applied to other occasion, all in protection scope of the present invention without to improve.
Claims (6)
1. an accurate temperature control tumor therapy instrument, comprise with the data processing control units of touch display screen, a plurality of A/D conversion circuit unit, PID temperature control system, a plurality of temperature transducer (2) and a plurality of temperature-controllable heater (1), it is characterized in that: the outfan of described a plurality of temperature transducer (2) is connected with the data processing control units input with touch screen respectively by A/D conversion circuit unit described in; The temperature survey outfan of a plurality of temperature-controllable heater (1) is connected with described PID temperature control system input respectively by A/D conversion circuit unit described in; Be implanted in tumor tissues (3) respectively by described a plurality of temperature-controllable heater (1), described a plurality of temperature transducer (2) is implanted in the region that described tumor tissues (3) has a common boundary with normal structure (4) respectively; After opening accurate temperature control tumor therapy instrument power supply, described a plurality of temperature-controllable heater (1) is to described tumor tissues (3) continuous heating, and the temperature analog signal that a plurality of temperature transducer (2) and a plurality of temperature-controllable heater (1) gather is converted to digital signal by A/D converter and transfers to the described data processing control units with touch display screen and PID temperature control system; Described PID temperature control system and with the data processing control units of touch display screen by the heating and temperature control of each temperature-controllable heater (1) described predetermined value or 42.5 DEG C; After the measuring tempeature value of a plurality of temperature transducers (2) being implanted in described tumor tissues (3) and described normal structure (4) juncture area also reaches predetermined value or 42.5 DEG C, the caloric value that all temperature-controllable heaters (1) export is only and maintains tumor tissues (3) and to be in needed for predetermined value or 42.5 DEG C and to continue one period of scheduled time for needed for treatment tumor tissues (3).
2. accurate temperature control tumor therapy instrument according to claim 1, it is characterized in that: described PID temperature control system comprises PID temperature control circuit unit and multiple solid-state relay, the hot output terminal that adds of described PID temperature control circuit unit is connected with the heating current input of temperature-controllable heater (1) described in each by described solid-state relay; The input of described PID temperature control circuit unit is connected by the temperature survey end of described A/D conversion circuit unit with each temperature-controllable heater (1).
3. accurate temperature control tumor therapy instrument according to claim 1, is characterized in that: the described data processing control units with touch display screen is connected with an alarm unit.
4. accurate temperature control tumor therapy instrument according to claim 3, is characterized in that: the described data processing control units with touch display screen is connected with described PID temperature control system, for setting and amendment pid parameter.
5. accurate temperature control tumor therapy instrument according to claim 1, it is characterized in that: described temperature transducer (2) comprises a platinum resistance (24), described platinum resistance (24) connects temperature transducer positive wire (21), thermometric heat sensor working zero line (22) and thermometric heat sensor cathode conductor (23) at least respectively.
6. according to claim 1 to 5 accurate temperature control tumor therapy instrument described in any one, it is characterized in that: described temperature-controllable heater (1) comprises heater (11) and temperature sensor (12), it is inner that described temperature sensor (12) is placed in heater (11); Described heater (11) two ends are connected with the positive wire (111) of temperature-controllable heater (1) heating current input and cathode conductor (112) respectively; Described temperature sensor (12) comprises a platinum resistance, and described platinum resistance connects temperature sensor positive wire (121), temperature sensor working zero line (122) and temperature sensor cathode conductor (123) at least respectively.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410558448.5A CN104224434B (en) | 2010-11-10 | 2010-11-10 | Accurate temperature control tumor therapy instrument |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410558448.5A CN104224434B (en) | 2010-11-10 | 2010-11-10 | Accurate temperature control tumor therapy instrument |
| CN2010105371851A CN101972188A (en) | 2010-11-10 | 2010-11-10 | Precise temperature-controlling tumor therapeutic apparatus and control method thereof |
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| CN2010105371851A Division CN101972188A (en) | 2010-11-10 | 2010-11-10 | Precise temperature-controlling tumor therapeutic apparatus and control method thereof |
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| CN104224434B CN104224434B (en) | 2016-09-14 |
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| JP4263406B2 (en) * | 1999-09-13 | 2009-05-13 | サントル ナショナル ドゥ ラ ルシュルシュ シャンティフィク（セ・エヌ・エル・エス） | Apparatus for heat treatment of biological tissue and use thereof |
| CN101972188A (en) * | 2010-11-10 | 2011-02-16 | 韩俊江 | Precise temperature-controlling tumor therapeutic apparatus and control method thereof |
| CN201855332U (en) * | 2010-11-10 | 2011-06-08 | 韩俊江 | Accurate temperature control tumor therapy instrument |
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2010
- 2010-11-10 CN CN201410558448.5A patent/CN104224434B/en not_active Expired - Fee Related
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2295470Y (en) * | 1996-03-11 | 1998-10-28 | 川北医学院附属医院 | Warming therapeutical instrument for rectum |
| CN2320224Y (en) * | 1997-11-14 | 1999-05-26 | 董信 | Portable body cavity heating therapeutic equipment |
| JP4263406B2 (en) * | 1999-09-13 | 2009-05-13 | サントル ナショナル ドゥ ラ ルシュルシュ シャンティフィク（セ・エヌ・エル・エス） | Apparatus for heat treatment of biological tissue and use thereof |
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| CN1868415A (en) * | 2006-06-30 | 2006-11-29 | 南京福中信息产业集团有限公司 | Cold circulation microwave tumor therapeutic apparatus |
| US20080281322A1 (en) * | 2007-05-11 | 2008-11-13 | Ablation Frontiers, Inc. | RF Energy Delivery System and Method |
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Effective date of registration: 20170718 Address after: 100058, No. 2, gate 3, building 20, East Hospital, No. 242 Che Zhuang West Road, Beijing, Haidian District Co-patentee after: Qiang Li Qiang Patentee after: Han Junjiang Address before: Jiangdong District 315040 Zhejiang city of Ningbo Province Ning Chuan Road No. 292 gold homes 4 Room 606 No. 18 Patentee before: Yu Li |
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