CN104224232A - Ultrasonic harmonic imaging method and device - Google Patents
Ultrasonic harmonic imaging method and device Download PDFInfo
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- CN104224232A CN104224232A CN201410496619.6A CN201410496619A CN104224232A CN 104224232 A CN104224232 A CN 104224232A CN 201410496619 A CN201410496619 A CN 201410496619A CN 104224232 A CN104224232 A CN 104224232A
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Abstract
The invention discloses an ultrasonic harmonic imaging method and device. The method comprises the following steps: receiving an original signal; performing empirical mode decomposition on the original signal to obtain a plurality of intrinsic mode function components and a margin component; selecting a part or all of the intrinsic mode function components and adding to obtain a harmonic signal; de-enveloping the harmonic signal to obtain a harmonic image. The ultrasonic harmonic imaging method can obtain the harmonic image with an extremely high harmonic component, and can obviously improve the harmonic-fundamental wave proportion while the signal-to-noise ratio is greatly improved.
Description
Technical field
The present invention relates to medical ultrasound system, particularly relate to a kind of Ultrasound Harmonic Imaging method and device.
Background technology
For ultrasonic system, human body is a complicated medium.Different organs and tissue, comprising pathological tissue all has its specific acoustic impedance and attenuation characteristic.Inject in body when ultrasonic, by surface to deep when different the organizing, the difference in the difference on this acoustic impedance and decay makes sound wave occur different reflections and decay.This different reflection is exactly the basis forming ultrasonoscopy with decay.The echo that ultrasound scanner will receive, strong and weak according to echo, be presented at successively on shadow screen with the luminous point that light and shade is different, then can show the section ultrasonoscopy of human body.
And the different tissues of human body, organ is all nonrigid media, therefore, when reflective sound wave, while being launched by signal consistent for same tranmitting frequency, self is due to the vibration of sound wave, encourage and occur resonance, producing the harmonic components be in lower frequency range.This harmonic wave is utilized namely to be called as Ultrasound Harmonic Imaging to carry out imaging, contrast agent harmonic imaging when comprising tissue harmonic imaging and use contrast agent.Harmonic imaging is compared with common Fundamental Imaging, has imaging frequency high, and resolving power is high, and noise jamming is few, intrinsic signal noise ratio (snr) of image advantages of higher, and its value comes into one's own day by day.
In harmonic imaging, it is less that harmonic components compares ratio with first-harmonic composition, finds suitable method to there is huge challenge to the extraction carrying out harmonic wave.Traditional method all can not remove the first-harmonic composition in signal effectively as phase place reverse impulse imaging etc., often obtain the image that still first-harmonic and harmonic wave are obscured, make picture quality limited.
Summary of the invention
The object of the present invention is to provide a kind of Ultrasound Harmonic Imaging method and device.
One of for achieving the above object, an embodiment of the present invention provides a kind of Ultrasound Harmonic Imaging method, comprises step:
Receive primary signal;
Empirical mode decomposition is carried out to described primary signal, obtains several intrinsic mode function components and a surplus component;
Choose the wherein part or all of of several intrinsic mode function components described and be added, obtaining harmonic signal;
Solution envelope processing is carried out to described harmonic signal, obtains harmonic image.
As the further improvement of an embodiment of the present invention, described harmonic signal is added by the described intrinsic mode function component identical with the frequency of the harmonic components in described primary signal and obtains.
As the further improvement of an embodiment of the present invention, step " reception primary signal " is front also comprises step:
Launch the first impulse wave, receive and obtain the first pulse signal;
Launch the second impulse wave, receive and obtain the second pulse signal;
Described first pulse signal is added with described second pulse signal, obtains described primary signal.
As the further improvement of an embodiment of the present invention, described first pulse signal is identical with the size of described second pulse signal, and phase place is contrary.
As the further improvement of an embodiment of the present invention, described primary signal is radiofrequency signal.
One of for achieving the above object, an embodiment of the present invention provides a kind of Ultrasound Harmonic Imaging device, comprises receiver module, decomposing module, selection module and image-forming module, and receiver module is for receiving the primary signal of returning from the internal feedback of examiner's body; Decomposing module is used for carrying out empirical mode decomposition to described primary signal, obtains several intrinsic mode function components and a surplus component; Select module for choosing the wherein part or all of of several intrinsic mode function components described and being added, obtain harmonic signal; Image-forming module is used for carrying out solution envelope processing to described harmonic signal, obtains harmonic image.
As the further improvement of an embodiment of the present invention, described harmonic signal is added by the described intrinsic mode function component identical with the frequency of the harmonic components in described primary signal and obtains.
As the further improvement of an embodiment of the present invention, described imaging device also comprises transmitter module, involves examiner described in the second pulse arrival for launching the first pulse successively; Wherein, when described transmitter module launches described first impulse wave, described receiver module receives described first impulse wave and obtains the first pulse signal, when described transmitter module launches described second impulse wave, described receiver module receives described second impulse wave and obtains the second pulse signal, and described first pulse signal and described second pulse signal are added and obtain described primary signal by described receiver module.
As the further improvement of an embodiment of the present invention, described first pulse signal is identical with the size of described second pulse signal, and phase place is contrary.
As the further improvement of an embodiment of the present invention, described primary signal is radiofrequency signal.
Compared with prior art, Ultrasound Harmonic Imaging method of the present invention can obtain the high harmonic image of harmonic components, while signal to noise ratio increases substantially, can significantly improve " harmonic wave-first-harmonic " ratio.
Accompanying drawing explanation
Fig. 1 is the Ultrasound Harmonic Imaging method flow diagram of an embodiment of the present invention.
Fig. 2 is a kind of Ultrasound Harmonic Imaging device frame schematic diagram of an embodiment of the present invention.
Detailed description of the invention
Describe the present invention below with reference to detailed description of the invention shown in the drawings.But these embodiments do not limit the present invention, the structure that those of ordinary skill in the art makes according to these embodiments, method or conversion functionally are all included in protection scope of the present invention.
As shown in Figure 1, be the Ultrasound Harmonic Imaging method flow diagram of an embodiment of the present invention, comprise the following steps:
S1: receive primary signal;
S2: carry out empirical mode decomposition (Emprical Mode Decompostion, EMD) to described primary signal, obtains several intrinsic mode functions (Intrinsic mode function, IMF) component and a surplus component;
S3: choose the wherein part or all of of several intrinsic mode function components described and be added, obtaining harmonic signal;
S4: solution envelope processing is carried out to described harmonic signal, obtains harmonic image.
Wherein, described harmonic signal is added by the described intrinsic mode function component identical with the frequency of the harmonic components in described primary signal and obtains, and namely can choose several intrinsic mode function components identical with harmonic components frequency as the component finally forming harmonic image according to the situation analysis of the harmonic components in actual primary signal.Primary signal can be obtained by phase place reverse impulse imaging mode, namely before step S1, also step is comprised: launch the first pulse arrival examiner, first impulse wave by examiner's body surface to deep through different tissues, then to feed back, receive and obtain the first pulse signal; Then launch the second pulse arrival examiner, the second impulse wave by examiner's body surface to deep through different tissues, then to feed back, receive and obtain the second pulse signal.It is the impulse wave launched successively that first pulse involves the second impulse wave, and is launch the second impulse wave again after the first impulse wave receives, and the first pulse involves identical sized by the second impulse wave, that phase place is contrary impulse wave.Then, the first pulse signal received and the second pulse signal are added, the primary signal described in step S1 can be obtained.First pulse signal and the second pulse signal all comprise fundamental signal and harmonic signal, size is identical in theory for the fundamental signal of the first pulse signal and the fundamental signal of the second pulse signal, phase place is contrary, fundamental signal can be made to offset when the first pulse signal and the second pulse signal are added, and harmonic signal can superpose, but in practical situation, be added in the primary signal obtained and still comprise fundamental signal, and the ratio of harmonic signal is lower, therefore, receive the primary signal obtained and also need further process, namely continue to perform step S1-S4 as above.The primary signal of present embodiment is not limited only to be obtained by above-mentioned phase place reverse impulse imaging mode, also can be other arbitrary signal, described primary signal can be radiofrequency signal, can receive and obtain some groups of radiofrequency signals, carrying out above-mentioned steps S1-S4 to often organizing radiofrequency signal again, finally can obtain new harmonic image.The pulse signal that same phase reverse impulse imaging mode obtains directly carries out separating the image that obtains of envelope processing and compares, harmonic image signal to noise ratio after use experience mode decomposition and radiography tissue contrast all have significantly improving of statistical significance, the new Ultrasound Harmonic Imaging method that present embodiment proposes can be stablized and effectively extract the harmonic components in primary signal, obtains the real harmonic image with high s/n ratio and tissue contrast contrast.
The Ultrasound Harmonic Imaging method of an embodiment of the present invention is just described in detail in detail with a concrete example below.Described method comprises:
First, phase place reverse impulse imaging mode is utilized to obtain primary signal s (t);
Then, carry out empirical mode decomposition to described primary signal s (t), empirical mode decomposition is the intrinsic mode function selecting limited quantity according to data itself adaptively, decomposes primary signal.With traditional Fourier transformation, wavelet transformation is different, this method is determine based on the wave characteristic of signal self for the decomposition of signal, effectively avoid the linear base that presets for the impact of signal decomposition, and the intrinsic mode function IMF obtained generally can be mapped with certain influence factor.This has with regard to making the analysis of empirical mode decomposition method in nonlinear and nonstationary process the advantage that can not be substituted.The detailed process of empirical mode decomposition is as follows:
(1) find out local maximum and the local minimum of primary signal s (t), utilize cubic spline curve that described maximum and minimum are connected to form coenvelope line T (t) and lower envelope D (t) respectively;
(2) average envelope m is calculated
1t (), namely calculates the average of coenvelope line T (t) and lower envelope line D (t), m
1t ()=[T (t)-D (t)], by average envelope m
1t () is removed and is obtained a new function k from primary signal s (t)
1(t), new function k
1t () is expressed as k
1(t)=s (t)-m
1(t);
(3) this new function k is checked
1t whether () be intrinsic mode function, namely checks new function k
1t whether () meet two conditions simultaneously: 1, new function k
1t the number of () zero crossing is equal with the number of extreme point, or number difference is no more than one; 2. the average envelope value determined by coenvelope line and lower envelope line at its random time point is zero; If new function k
1t () meets above two conditions, then new function k
1t () is intrinsic mode function, i.e. IMF, if new function k
1t () is discontented is enough to two conditions, then make s (t)=k
1t (), is about to new function k now
1t () regards primary signal as, repeat above-mentioned empirical mode decomposition step, i.e. k
2(t)=k
1(t)-m
2(t), wherein m
2t () is k
1t the coenvelope line of () and the meansigma methods of lower envelope line, repeat above-mentioned empirical mode decomposition step, until the new function k obtained
nt () meets two conditions of intrinsic mode function, now namely obtain first intrinsic mode function component IMF
1, by first intrinsic mode function component IMF
1be expressed as c
1=k
n(t);
(4) from primary signal, described intrinsic mode function component IMF is removed
1, obtain a surplus component r
1(t), surplus component r
1(t)=s (t)-c
1, to surplus component r
1t () performs above-mentioned empirical mode decomposition step, obtain second intrinsic mode function component IMF
2, i.e. c
2, surplus component r now
2(t)=r
1(t)-c
2, repeat above-mentioned empirical mode decomposition step, until certain surplus component r
n(t) or certain intrinsic mode function component c
nbe less than a default value interested or surplus component r
nwhen () is for monotonic function t, empirical mode decomposition procedure ends, now, primary signal s (t) can be represented as:
Namely primary signal s (t) is broken down into a series of intrinsic mode function component c
jwith a surplus component r
n(t).Empirical mode decomposition process is exactly directly from primary signal, extract the component relevant to certain time scale, after extracted representation in components is become intrinsic mode function, they all have good Hilbert transform character, thus, just can calculate its instantaneous frequency further, so just can to any time localization in time domain.
Then, choose the wherein part or all of of several intrinsic mode function components described and be added, obtain harmonic signal, described harmonic signal is added by the described intrinsic mode function component identical with the frequency of the harmonic components in described primary signal and obtains, and namely can choose several intrinsic mode function components identical with harmonic components frequency as the component finally forming harmonic image according to the situation analysis of the harmonic components in actual primary signal.
Finally, solution envelope processing is carried out to described harmonic signal, obtains harmonic image.The pulse signal that same phase reverse impulse imaging mode obtains directly carries out separating the image that obtains of envelope processing and compares, signal noise ratio (snr) of image after use experience mode decomposition and radiography tissue contrast all have significantly improving of statistical significance, the new Ultrasound Harmonic Imaging method that present embodiment proposes can be stablized and effectively extract the harmonic components in primary signal, obtains the real harmonic image with high s/n ratio and tissue contrast contrast.
Present embodiment adopts empirical mode decomposition method, the primary signal collected is decomposed, some the intrinsic mode function components corresponding to harmonic components then can be found from a series of intrinsic mode functions after decomposition, and remove the irrelevant component of same harmonic components, carry out follow-up operation again, finally just can obtain the high harmonic image of harmonic components, compare with traditional method, present embodiment is while signal to noise ratio increases substantially, " harmonic wave-first-harmonic " ratio can be significantly improved, height " radiography-tissue " contrast (Contrast to Tissue ratio such as in contrast agent imaging, CTR).The Ultrasound Harmonic Imaging method good stability that present embodiment proposes, imaging results is reliable, and printenv selection etc., can use in the middle of all harmonic imaging application in contrast agent imaging comprised.The empirical mode decomposition that present embodiment uses is a kind of nonlinear data processing method, is decomposed signal by the wave characteristic of signal itself, effectively avoids the linear base that presets for the impact of signal decomposition.
As shown in Figure 2, be a kind of Ultrasound Harmonic Imaging device that an embodiment of the present invention provides, described device comprises: receiver module 100, decomposing module 200, selection module 300 and image-forming module 400.Receiver module 100 is for receiving the primary signal of returning from the internal feedback of examiner's body; Decomposing module 200, for carrying out empirical mode decomposition to described primary signal, obtains several intrinsic mode function components and a surplus component; Select module 300 for choosing the wherein part or all of of several intrinsic mode function components described and being added, obtain harmonic signal; Image-forming module 400, for carrying out solution envelope processing to described harmonic signal, obtains harmonic image.
Wherein, described harmonic signal is added by the described intrinsic mode function component identical with the frequency of the harmonic components in described primary signal and obtains, and namely can choose several intrinsic mode function components identical with harmonic components frequency as the component finally forming harmonic image according to the situation analysis of the harmonic components in actual primary signal.Described device also comprises transmitter module, involves examiner described in the second pulse arrival for launching the first pulse successively.Wherein, when described transmitter module launches described first impulse wave, described receiver module 100 receives described first impulse wave and obtains the first pulse signal, when described transmitter module launches described second impulse wave, described receiver module 100 receives described second impulse wave and obtains the second pulse signal.It is the impulse wave launched successively that first pulse involves the second impulse wave, and is launch the second impulse wave again after the first impulse wave receives, and the first pulse involves identical sized by the second impulse wave, that phase place is contrary impulse wave.The first pulse signal of receiving and the second pulse signal are added by receiver module 100, can obtain primary signal, but not as limit, such as, can comprise computing module, are added for the first pulse signal that will receive and the second pulse signal.First pulse signal and the second pulse signal all comprise fundamental signal and harmonic signal, size is identical in theory for the fundamental signal of the first pulse signal and the fundamental signal of the second pulse signal, phase place is contrary, fundamental signal can be made to offset when the first pulse signal and the second pulse signal are added, and harmonic signal can superpose, but in practical situation, be added in the primary signal obtained and still comprise fundamental signal, and the ratio of harmonic signal is lower, therefore, receive the primary signal obtained and also need further process.The primary signal of present embodiment is not limited only to be obtained by above-mentioned phase place reverse impulse imaging mode, also can be other arbitrary signal, described primary signal can be radiofrequency signal, can receive and obtain some groups of radiofrequency signals, carry out empirical mode decomposition to often organizing radiofrequency signal and separate envelope etc. again, finally can obtain new harmonic image.The pulse signal that same phase reverse impulse imaging mode obtains directly carries out separating the image that obtains of envelope processing and compares, harmonic image signal to noise ratio after use experience mode decomposition and radiography tissue contrast all have significantly improving of statistical significance, the new Ultrasound Harmonic Imaging method that present embodiment proposes can be stablized and effectively extract the harmonic components in primary signal, obtains the real harmonic image with high s/n ratio and tissue contrast contrast.
Those skilled in the art can be well understood to, and for convenience and simplicity of description, the specific works process of the module of foregoing description, with reference to the corresponding process in preceding method embodiment, can not repeat them here.
Be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, technical scheme in each embodiment also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.
A series of detailed description listed is above only illustrating for feasibility embodiment of the present invention; they are also not used to limit the scope of the invention, all do not depart from the skill of the present invention equivalent implementations done of spirit or change all should be included within protection scope of the present invention.
Claims (10)
1. a Ultrasound Harmonic Imaging method, is characterized in that comprising step:
Receive primary signal;
Empirical mode decomposition is carried out to described primary signal, obtains several intrinsic mode function components and a surplus component;
Choose the wherein part or all of of several intrinsic mode function components described and be added, obtaining harmonic signal;
Solution envelope processing is carried out to described harmonic signal, obtains harmonic image.
2. Ultrasound Harmonic Imaging method as claimed in claim 1, it is characterized in that, described harmonic signal is added by the described intrinsic mode function component identical with the frequency of the harmonic components in described primary signal and obtains.
3. Ultrasound Harmonic Imaging method as claimed in claim 1, is characterized in that, also comprises step step " reception primary signal " is front:
Launch the first impulse wave, receive and obtain the first pulse signal;
Launch the second impulse wave, receive and obtain the second pulse signal;
Described first pulse signal is added with described second pulse signal, obtains described primary signal.
4. Ultrasound Harmonic Imaging method as claimed in claim 3, it is characterized in that, described first pulse signal is identical with the size of described second pulse signal, and phase place is contrary.
5. Ultrasound Harmonic Imaging method as claimed in claim 1, it is characterized in that, described primary signal is radiofrequency signal.
6. a Ultrasound Harmonic Imaging device, is characterized in that comprising:
Receiver module, for receiving the primary signal of returning from the internal feedback of examiner's body;
Decomposing module, for carrying out empirical mode decomposition to described primary signal, obtains several intrinsic mode function components and a surplus component;
Select module, for choosing the wherein part or all of of several intrinsic mode function components described and being added, obtain harmonic signal; And
Image-forming module, for carrying out solution envelope processing to described harmonic signal, obtains harmonic image.
7. Ultrasound Harmonic Imaging device as claimed in claim 6, it is characterized in that, described harmonic signal is added by the described intrinsic mode function component identical with the frequency of the harmonic components in described primary signal and obtains.
8. Ultrasound Harmonic Imaging device as claimed in claim 6, it is characterized in that, described imaging device also comprises:
Transmitter module, involves examiner described in the second pulse arrival for launching the first pulse successively;
Wherein, when described transmitter module launches described first impulse wave, described receiver module receives described first impulse wave and obtains the first pulse signal, when described transmitter module launches described second impulse wave, described receiver module receives described second impulse wave and obtains the second pulse signal, and described first pulse signal and described second pulse signal are added and obtain described primary signal by described receiver module.
9. Ultrasound Harmonic Imaging device as claimed in claim 7, it is characterized in that, described first pulse signal is identical with the size of described second pulse signal, and phase place is contrary.
10. Ultrasound Harmonic Imaging device as claimed in claim 6, it is characterized in that, described primary signal is radiofrequency signal.
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Application publication date: 20141224 |