One is treated beriberi Chinese medicine composition and preparation method thereof
Technical field
The present invention relates to beriberi nursing practical technique field, especially one and treat beriberi Chinese medicineComposition and method of making the same.
Background technology
Beriberi is a kind of extremely common fungal infection dermatoses. In adult, the people of 70-80% has pinGas, just weight difference. Be everlasting and increase the weight of summer, alleviate winter, also has people not heal all the year round.Comprise: erosive beriberi, vesicle beriberi, keratinization type beriberi.
At present, a lot of for the medicine of beriberi, as ZUGUANG SAN and a large amount of Western medicine ointment,Traditional Chinese herbal decoction etc.; But beriberi is a kind of obstinate, communicable fungal infection venereal diseaseDisease, for the effect of its treatment, in the prior art, only just can carry out short to beriberiThe temporarily alleviation of property, and can not make beriberi be uprooted thoroughly, for the healing of beriberiRate is lower, efficient lower; Beriberi recurrence period is short, and often in six months, beriberi willOccur, certainly, this also with beriberi itself along with seasonal variations, and reflect cure rate situationDifference, therefore, also can draw, beriberi is a kind of situation about changing along with environmental change,Be exactly serious in summer, the effect alleviating winter, makes in prior art for this reason, a large amount ofMedicine be all difficult to obtain Utopian effect for the treatment of beriberi, beriberi worry is followedPeople.
Based on this, this researcher according to beriberi along with environmental change situation and of the prior artThe research of setting out of medicine treatment situation, by exploration and research for many years, for treating beri-beri protectsReason brought a kind of new selection scheme, make beriberi cure rate and efficient obtained largerThe raising of degree, and can alleviate for a long time the illness of beriberi.
Summary of the invention
The invention provides one and treat beriberi Chinese medicine composition, can make the cure rate of beriberiReach more than 75%, reach 100% for the efficient of remissive treatment of beriberi, promote beriberi to damageHinder living again of skin histology, the recurrence rate of lower beriberi.
And the present invention also provides the preparation method who treats beriberi Chinese medicine composition in this.
Specifically be achieved by the following technical programs:
One is treated beriberi Chinese medicine composition, and its raw material composition (weight portion) is pine needle 3-10Part, pine tar 3-7 part, acorn nut 2-9 part, oak leaf 3-8 part, thorn bretschneider pear root 3-9 part, golden cypress 3-5Part, Asiatic plantain 20-30 part, purslane 10-15 part, rhizoma atractylodis 6-9 part, Chinese gall 3-9 part, woodMelon 3-7 part, Radix Glycyrrhizae 4-8 part.
Described material composition (weight portion) is 5 parts, pine needle, 6 parts of pine tars, 7 parts of acorn nuts, rubber5 parts of leaves, 7 parts of bretschneider pear roots of thorn, 4 parts of golden cypresses, 27 parts of Asiatic plantains, 11 parts of purslanes, rhizoma atractylodis 7Part, 5 parts, Chinese gall, 5 parts of pawpaws, 5 parts, Radix Glycyrrhizae.
Described material composition (weight portion) is 8 parts, pine needle, 5 parts of pine tars, 8 parts of acorn nuts, rubber7 parts of leaves, 5 parts of bretschneider pear roots of thorn, 3 parts of golden cypresses, 23 parts of Asiatic plantains, 13 parts of purslanes, rhizoma atractylodis 8Part, 4 parts, Chinese gall, 6 parts of pawpaws, 7 parts, Radix Glycyrrhizae.
The preparation method of Chinese medicine composition for this treatment beriberi, comprises the following steps:
(1) raw material processing: choose raw material according to said ratio part, and pine needle is placed in to boilerIn, be (1-3) according to material water weight ratio: (4-9) add clear water, then account for to adding in boilerThe salt of pine needle weight 1%, adjustment water temperature is 40-60 DEG C, after immersion treatment 20-30min, thenAdd successively wherein acorn nut, oak leaf, and water temperature is warming up to 90-100 DEG C, constant temperature soaks50-60min, more successively wherein every 5-7min add thorn bretschneider pear root, golden cypress, Asiatic plantain,Purslane, rhizoma atractylodis, Chinese gall, Radix Glycyrrhizae, pawpaw, pine tar, after to be added completing, takeProgramming rate is that 11-13 DEG C/min is warming up to 170-190 DEG C, and constant temperature decocts after 20-50min, thenAdd wherein the clarification limewash that accounts for Asiatic plantain weight 2-3%, continue constant temperature and decoct10-20min, then be cooled to 90-95 DEG C with 10 DEG C/min, constant temperature decocts 5-10min; Adjustment is fallenTemperature speed be 7 DEG C/min to be cooled to temperature be 50-70 DEG C, constant temperature decocts after 10min, is putIn cooler, be cooled to after 10-15 DEG C at 10-20s, obtain material liquid mixture stand-by;
(2) vacuum filtration: by step 1) material liquid mixture of finishing dealing with is placed in vacuum and isIn the vacuum filter of 0.02-0.08MPa, carry out filtration treatment, obtain filtrate and filter residue, stand-by;
(3) filtrate is concentrated: it is 40-60 DEG C that the filtrate that step 2 is processed to acquisition is placed in temperatureConcentrate, make filtrate be concentrated into three of stoste/for the moment, obtain concentrate, stand-by;
(4) filter residue is pulverized: by step 2) processing the filter residue obtaining, to be placed in temperature be 70-90 DEG CBaking box in, after baking 15-25min, then be placed in pulverizer, be ground into 80-100Order; Be placed on again temperature and be in the baking box of 40-70 DEG C, after baking 30-50min, then willIt is placed in pulverizer and is ground into after 180-210 order, obtains dregs of a decoction powder, stand-by;
(5) mix melt cinder: by step 3) concentrate and the step 4 that obtain) obtain dregs of a decoction powderEnd mixes, and adds the liquor potassic permanganate that accounts for dregs of a decoction powder weight 1-3%, simultaneouslyAdd the acetum that accounts for concentrate weight 5-7%, and to be placed on temperature be the environment of 2-5 DEG CIn, adopt after agitator stir process 1-3h, then 1000ml temperature is 20-25 DEG C whereinClear water, continues, after stir process 50-70min, to obtain turbid solution, stand-by;
(6) boil: by step 5) obtain turbid solution be placed in boiler, adopt temperature be50-80 DEG C of decoction, and be 30-70r/min stir process every 30min employing stirring speed10-15min, continues to decoct after 4-7h, obtains suspension, can obtain treatment beriberi Chinese medicineComposition.
The mass concentration of described liquor potassic permanganate is 14-18%.
The mass concentration of described liquor potassic permanganate is 16%.
Compared with prior art, technique effect of the present invention is embodied in:
1. by pine needle, pine tar, acorn nut, oak leaf, thorn bretschneider pear root, golden cypress, Asiatic plantain,The appropriate proportioning of purslane, rhizoma atractylodis, Chinese gall, pawpaw, licorice raw material, and in conjunction with this Chinese medicineIn composition preparation process, for the adding of the immersion of saline solution, clarification limewash, permanganic acidThe preparation of potassium solution, and each raw material is carried out to raw material processing, vacuum filtration, filtrate are concentrated, filterGround-slag is broken, slag liquid mixes, boils step, makes the drug effect of this treatment beriberi Chinese medicine compositionComposition is retained and removal accurately, makes the effective ingredient of each raw material that complicated microcosmic occurChange, and then improve beriberi the effective elements of the medicine, this medicine is not felt in the time for the treatment of beriberiStimulation, shouting pain, spread upon beriberi affected part, makes affected part refrigerant, can promote affected part blood flowLogical, reach the object of the lower bacterium of comprehensive removing, improve the cure rate of beriberi and efficient,Reduce the recurrence rate of beriberi.
2. the invention provides the cure rate that treatment beriberi Chinese medicine composition can make beriberiReach more than 75%, reach 100% for the remissive treatment of beriberi is efficient, make answering of beriberiThe rate of sending out maintains 11-13%, and then selects for the treatment field of beriberi provides a kind of new medicationSelect, people are reduced for treatment and the nursing cost of beriberi, effect is better.
3. treatment beriberi of the present invention can be alleviated beriberi for a long time with Chinese medicine compositionRecurrence, makes beriberi for a long time in nice and cool environment, exactly can be by the smearing of this medicine,Make the pin winter environment in simulation for a long time, and then the breeding of restriction beriberi fungi, pin reducedThe infected rate of gas, and then improved the cure rate of beriberi and efficient.
Detailed description of the invention
Below in conjunction with concrete embodiment, technical scheme of the present invention is done to further limitFixed, but claimed scope is not only confined to done description.
Embodiment 1
One is treated beriberi Chinese medicine composition, its raw material be pine needle 3g, pine tar 3g, acorn nut 2g,Oak leaf 3g, thorn bretschneider pear root 3g, golden cypress 3g, Asiatic plantain 20g, purslane 10g, rhizoma atractylodis 6g,Chinese gall 3g, pawpaw 3g, Radix Glycyrrhizae 4g.
Its preparation method, comprises the following steps:
(1) raw material processing: choose raw material according to said ratio part, and pine needle is placed in to boilerIn, be that 1:4 adds clear water according to material water weight ratio, then account for pine needle weight 1% to adding in boilerSalt, adjust water temperature be 40 DEG C, after immersion treatment 20min, then add successively wherein rubberSon, oak leaf, and water temperature is warming up to 90 DEG C, constant temperature soaks 50min, more successively whereinAdd thorn bretschneider pear root, golden cypress, Asiatic plantain, purslane, rhizoma atractylodis, Chinese gall, sweet every 5minGrass, pawpaw, pine tar, after to be added completing, taking programming rate is that 11 DEG C/min is warming up to170 DEG C, constant temperature decocts after 20min, then adds wherein the clarification stone that accounts for Asiatic plantain weight 2%Buck, continues constant temperature and decocts 10min, then be cooled to 90 DEG C with 10 DEG C/min, and constant temperature decocts 5min;Adjusting cooling rate and be 7 DEG C/min, to be cooled to temperature be 50 DEG C, and constant temperature decocts after 10min, by itBe placed in cooler, be cooled to after 10 DEG C at 10s, obtain material liquid mixture stand-by;
(2) vacuum filtration: by step 1) material liquid mixture of finishing dealing with is placed in vacuum and isIn the vacuum filter of 0.02MPa, carry out filtration treatment, obtain filtrate and filter residue, stand-by;
(3) filtrate is concentrated: the filtrate that step 2 is processed to acquisition is placed in temperature and is 40 DEG C and carries outConcentrated, make filtrate be concentrated into three of stoste/for the moment, obtain concentrate, stand-by;
(4) filter residue is pulverized: by step 2) processing the filter residue obtaining, to be placed in temperature be the baking of 70 DEG CIn baking box, after baking 15min, then be placed in pulverizer, be ground into 80 orders; Again by itBe placed in temperature and be the baking box of 40 DEG C, after baking 30min, then be placed on powder in pulverizerBe broken into after 180 orders, obtain dregs of a decoction powder, stand-by;
(5) mix melt cinder: by step 3) concentrate and the step 4 that obtain) obtain dregs of a decoction powderEnd mixes, and adds the liquor potassic permanganate that accounts for dregs of a decoction powder weight 1%, Gao MengThe mass concentration of acid potassium solution is 16%. Add the acetum that accounts for concentrate weight 5% simultaneously,And to be placed on temperature be in the environment of 2 DEG C, adopt after agitator stir process 1h, then to itMiddle 1000ml temperature is the clear water of 20 DEG C, continues, after stir process 50min, to obtain turbid solution,Stand-by;
(6) boil: by step 5) obtain turbid solution be placed in boiler, adopt temperature be 50 DEG CDecoct, and be 30r/min stir process 10min every 30min employing stirring speed, continueDecoct after 4h, obtain suspension, can obtain treatment beriberi Chinese medicine composition.
Embodiment 2
One is treated beriberi Chinese medicine composition, and its raw material is pine needle 10g, pine tar 7g, acorn nut9g, oak leaf 8g, thorn bretschneider pear root 9g, golden cypress 5g, Asiatic plantain 30g, purslane 15g, rhizoma atractylodis9g, Chinese gall 9g, pawpaw 7g, Radix Glycyrrhizae 8g.
Its preparation method, comprises the following steps:
(1) raw material processing: choose raw material according to said ratio part, and pine needle is placed in to boilerIn, be that 1:3 adds clear water according to material water weight ratio, then account for pine needle weight 1% to adding in boilerSalt, adjust water temperature be 60 DEG C, after immersion treatment 30min, then add successively wherein rubberSon, oak leaf, and water temperature is warming up to 100 DEG C, constant temperature soaks 60min, more successively whereinAdd thorn bretschneider pear root, golden cypress, Asiatic plantain, purslane, rhizoma atractylodis, Chinese gall, sweet every 7minGrass, pawpaw, pine tar, after to be added completing, taking programming rate is that 13 DEG C/min is warming up to190 DEG C, constant temperature decocts after 50min, then adds wherein the clarification stone that accounts for Asiatic plantain weight 3%Buck, continues constant temperature and decocts 20min, then be cooled to 95 DEG C with 10 DEG C/min, and constant temperature decocts10min; Adjusting cooling rate and be 7 DEG C/min, to be cooled to temperature be 70 DEG C, and constant temperature decocts 10minAfter, be placed in cooler, be cooled to after 15 DEG C at 20s, obtain material liquid mixture stand-by;
(2) vacuum filtration: by step 1) material liquid mixture of finishing dealing with is placed in vacuum and isIn the vacuum filter of 0.08MPa, carry out filtration treatment, obtain filtrate and filter residue, stand-by;
(3) filtrate is concentrated: the filtrate that step 2 is processed to acquisition is placed in temperature and is 60 DEG C and carries outConcentrated, make filtrate be concentrated into three of stoste/for the moment, obtain concentrate, stand-by;
(4) filter residue is pulverized: by step 2) processing the filter residue obtaining, to be placed in temperature be the baking of 90 DEG CIn baking box, after baking 25min, then be placed in pulverizer, be ground into 100 orders; Again by itBe placed in temperature and be the baking box of 70 DEG C, after baking 50min, then be placed on powder in pulverizerBe broken into after 210 orders, obtain dregs of a decoction powder, stand-by;
(5) mix melt cinder: by step 3) concentrate and the step 4 that obtain) obtain dregs of a decoction powderEnd mixes, and adds the liquor potassic permanganate that accounts for dregs of a decoction powder weight 3%, Gao MengThe mass concentration of acid potassium solution is 18%. Add the acetum that accounts for concentrate weight 7% simultaneously,And to be placed on temperature be in the environment of 5 DEG C, adopt after agitator stir process 3h, then to itMiddle 1000ml temperature is the clear water of 25 DEG C, continues, after stir process 70min, to obtain turbid solution,Stand-by;
(6) boil: by step 5) obtain turbid solution be placed in boiler, adopt temperature be 80 DEG CDecoct, and be 70r/min stir process 15min every 30min employing stirring speed, continueDecoct after 7h, obtain suspension, can obtain treatment beriberi Chinese medicine composition.
Embodiment 3
One is treated beriberi Chinese medicine composition, its raw material be pine needle 5g, pine tar 6g, acorn nut 7g,Oak leaf 5g, thorn bretschneider pear root 7g, golden cypress 4g, Asiatic plantain 27g, purslane 11g, rhizoma atractylodis 7g,Chinese gall 5g, pawpaw 5g, Radix Glycyrrhizae 5g.
Its preparation method, comprises the following steps:
(1) raw material processing: choose raw material according to said ratio part, and pine needle is placed in to boilerIn, be that 2:5 adds clear water according to material water weight ratio, then account for pine needle weight 1% to adding in boilerSalt, adjust water temperature be 50 DEG C, after immersion treatment 25min, then add successively wherein rubberSon, oak leaf, and water temperature is warming up to 95 DEG C, constant temperature soaks 55min, more successively whereinAdd thorn bretschneider pear root, golden cypress, Asiatic plantain, purslane, rhizoma atractylodis, Chinese gall, sweet every 6minGrass, pawpaw, pine tar, after to be added completing, taking programming rate is that 12 DEG C/min is warming up to180 DEG C, constant temperature decocts after 35min, then adds wherein the clarification stone that accounts for Asiatic plantain weight 2.5%Buck, continues constant temperature and decocts 15min, then be cooled to 93 DEG C with 10 DEG C/min, and constant temperature decocts 8min;Adjusting cooling rate and be 7 DEG C/min, to be cooled to temperature be 60 DEG C, and constant temperature decocts after 10min, by itBe placed in cooler, be cooled to after 13 DEG C at 15s, obtain material liquid mixture stand-by;
(2) vacuum filtration: by step 1) material liquid mixture of finishing dealing with is placed in vacuum and isIn the vacuum filter of 0.05MPa, carry out filtration treatment, obtain filtrate and filter residue, stand-by;
(3) filtrate is concentrated: the filtrate that step 2 is processed to acquisition is placed in temperature and is 50 DEG C and carries outConcentrated, make filtrate be concentrated into three of stoste/for the moment, obtain concentrate, stand-by;
(4) filter residue is pulverized: by step 2) processing the filter residue obtaining, to be placed in temperature be the baking of 80 DEG CIn baking box, after baking 20min, then be placed in pulverizer, be ground into 90 orders; Again by itBe placed in temperature and be the baking box of 55 DEG C, after baking 40min, then be placed on powder in pulverizerBe broken into after 195 orders, obtain dregs of a decoction powder, stand-by;
(5) mix melt cinder: by step 3) concentrate and the step 4 that obtain) obtain dregs of a decoction powderEnd mixes, and adds the liquor potassic permanganate that accounts for dregs of a decoction powder weight 2%, Gao MengThe mass concentration of acid potassium solution is 14%. Add the acetum that accounts for concentrate weight 6% simultaneously,And to be placed on temperature be in the environment of 3 DEG C, adopt after agitator stir process 2h, then to itMiddle 1000ml temperature is the clear water of 23 DEG C, continues, after stir process 60min, to obtain turbid solution,Stand-by;
(6) boil: by step 5) obtain turbid solution be placed in boiler, adopt temperature be 65 DEG CDecoct, and be 50r/min stir process 11min every 30min employing stirring speed, continueDecoct after 5h, obtain suspension, can obtain treatment beriberi Chinese medicine composition.
Embodiment 4
One is treated beriberi Chinese medicine composition, its raw material be pine needle 8g, pine tar 5g, acorn nut 8g,Oak leaf 7g, thorn bretschneider pear root 5g, golden cypress 3g, Asiatic plantain 23g, purslane 13g, rhizoma atractylodis 8g,Chinese gall 4g, pawpaw 6g, Radix Glycyrrhizae 7g.
The preparation method of Chinese medicine composition for this treatment beriberi, comprises the following steps:
(1) raw material processing: choose raw material according to said ratio part, and pine needle is placed in to boilerIn, be that 2:7 adds clear water according to material water weight ratio, then account for pine needle weight 1% to adding in boilerSalt, adjust water temperature be 55 DEG C, after immersion treatment 27min, then add successively wherein rubberSon, oak leaf, and water temperature is warming up to 93 DEG C, constant temperature soaks 52min, more successively whereinAdd thorn bretschneider pear root, golden cypress, Asiatic plantain, purslane, rhizoma atractylodis, Chinese gall, sweet every 7minGrass, pawpaw, pine tar, after to be added completing, taking programming rate is that 13 DEG C/min is warming up to185 DEG C, constant temperature decocts after 40min, then adds wherein the clarification stone that accounts for Asiatic plantain weight 3%Buck, continues constant temperature and decocts 17min, then be cooled to 94 DEG C with 10 DEG C/min, and constant temperature decocts 9min;Adjusting cooling rate and be 7 DEG C/min, to be cooled to temperature be 65 DEG C, and constant temperature decocts after 10min, by itBe placed in cooler, be cooled to after 11 DEG C at 17s, obtain material liquid mixture stand-by;
(2) vacuum filtration: by step 1) material liquid mixture of finishing dealing with is placed in vacuum and isIn the vacuum filter of 0.07MPa, carry out filtration treatment, obtain filtrate and filter residue, stand-by;
(3) filtrate is concentrated: the filtrate that step 2 is processed to acquisition is placed in temperature and is 45 DEG C and carries outConcentrated, make filtrate be concentrated into three of stoste/for the moment, obtain concentrate, stand-by;
(4) filter residue is pulverized: by step 2) processing the filter residue obtaining, to be placed in temperature be the baking of 75 DEG CIn baking box, after baking 19min, then be placed in pulverizer, be ground into 85 orders; Again by itBe placed in temperature and be the baking box of 50 DEG C, after baking 45min, then be placed on powder in pulverizerBe broken into after 190 orders, obtain dregs of a decoction powder, stand-by;
(5) mix melt cinder: by step 3) concentrate and the step 4 that obtain) obtain dregs of a decoction powderEnd mixes, and adds the liquor potassic permanganate that accounts for dregs of a decoction powder weight 3%, Gao MengThe mass concentration of acid potassium solution is 16%. Add the acetum that accounts for concentrate weight 6% simultaneously,And to be placed on temperature be in the environment of 3 DEG C, adopt after agitator stir process 2h, then to itMiddle 1000ml temperature is the clear water of 24 DEG C, continues, after stir process 65min, to obtain turbid solution,Stand-by;
(6) boil: by step 5) obtain turbid solution be placed in boiler, adopt temperature be 75 DEG CDecoct, and be 65r/min stir process 11min every 30min employing stirring speed, continueDecoct after 5.5h, obtain suspension, can obtain treatment beriberi Chinese medicine composition.
It is important to point out at this, above embodiment only limits to technical scheme of the present invention to doFurther understanding and explanation, is not to further restriction of the present invention, art technologyPersonnel on this basis, the non-outstanding essential characteristics of making and the improvement of non-marked improvement,All belong to protection category of the present invention.