CN104173938B - A kind of Chinese medicine preparation treating tethered cord syndrome - Google Patents

Abstract

The invention discloses a kind of Chinese medicine preparation treating tethered cord syndrome, it is made up according to certain weight proportion of Herba Taxilli, Cortex Acanthopanciss, the Cortex Eucommiae, Radix Dipsaci, Herba Epimedii, Fructus Corni, Rhizoma Curculiginises, Radix Morindae Officinaliss, Rhizoma Homalomenae, Folium Photiniae (Folium Photiniae serrulatae), Radix Aconiti Lateralis Preparata, Cortex Cinnamomi, Radix Clematidis, Radix Cynanchi Paniculati, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Rhizoma Corydalis, Radix Curcumae, Radix Glycyrrhizae Preparata, there is liver and kidney tonifying, strengthening the tendons and bones, expelling wind and removing dampness, promoting blood circulation to restore menstrual flow, effect of dispersing cold for relieving pain, being capable of effectively treatment tethered cord syndrome.

Description

A kind of Chinese medicine preparation treating tethered cord syndrome

Technical field

The present invention relates to a kind of Chinese medicine preparation is and in particular to a kind of Chinese medicine preparation treating tethered cord syndrome.

Background technology

Tethered cord syndrome (tethered cord syndrome, TCS) refers to make due to congenital or posteriori factor Spinal cord is subject to tractive, circular cone low level, causes spinal cord the pathological changes such as ischemia, anoxia, nervous tissue degeneration, under clinically occurring The syndrome of limb sensation, dyskinesia or the nervous lesion such as deformity, defecation obstacle.The cause of disease of tethered cord syndrome can It is divided into constitutional and Secondary cases.Western medical treatment is loosened using operation and is tied, and the focus such as disect a lipoma.Operative treatment is likely to be breached Mitigation symptoms and the double effectses preventing disease progression, but operation generally can not make fecal and urinary functionses obstacle, lower limb and foot Deformation is improved, and delayed ischemic neurological deficits also cannot be improved.Chinese medicine thinks, diseases of spinal cord is often human splenocyte Renal function congenital defect or posteriori virtual loss, the vim and vigour being led to are not enough, and brain is hollow, and muscle weakness, feel failure, muscles and bones Wither soft, the generation of all myopathy such as amyotrophy.The only resource of Chinese traditional treatment myopathy is exactly that beneficial essence adds marrow, Psoralen gives birth to marrow, adjusts Give sb. a hard time the congenital of body or the day after tomorrow not enough, bone and muscle strengthening tissue regeneration promoting marrow, strong flesh Sheng Litong nerve.Through retrieval China national Patent Office patent Data base finds the Chinese medicine preparation having invention to be treatment spondylitiss, such as：CN01128976, CN03146637 etc., these Chinese medicine systems Agent employs some wind-damp dispelling, invigorating the liver and kidney, and the Chinese medicine of bone and muscle strengthening is it is seen that herbal treatment has huge potential.The traditional Chinese medical science is that have The traditional medicine of thousand of years history, at present, in the treatment to diseases of spinal cord, all having doctor trained in Western medicine can not replace the traditional Chinese medical science Effect（The combination of the particularly traditional Chinese medical science and modern science and technology）It will be apparent that compensate for the deficiency of western medical treatment, treatment by Chinese herbs good effect And toxic and side effects are few, it is possible to decrease the incidence rate of complication, expense is low, for the treatment of this disease, plays an important role.

Content of the invention

The present invention is in order to solve the problems, such as above-mentioned it is therefore an objective to provide a kind of Chinese medicine preparation to be used for treating tethered cord syndrome Problem, this Chinese medicine preparation has a good effect for tethered cord syndrome, and cure rate is high, has no toxic side effect, taking convenience, valency The cheap feature of lattice, improves the quality of life of tethered cord syndrome, decreases misery.

Inventor is in clinical treatment practice for many years it was observed that tethered cord syndrome patient clinical condition in the treatment Shape with painful, through lot of experiments, Exploration and conclusion goes out a kind of new formula of the Chinese medicine preparation treating tethered cord syndrome repeatedly, It is not only able to solve the problems, such as preoperative tethered cord syndrome well, the complication occurring after simultaneously can also preventing operative treatment Problem, treating both the principal and secondary aspects of a disease, promotion functions recover, and it is painful to be that patient releases.

The present invention selects Herba Taxilli, Cortex Acanthopanciss, the Cortex Eucommiae, Radix Dipsaci, Herba Epimedii, Fructus Corni, Rhizoma Curculiginises, Radix Morindae Officinaliss, Rhizoma Homalomenae, stone Nanmu leaf, Radix Aconiti Lateralis Preparata, Cortex Cinnamomi, Radix Clematidis, Radix Cynanchi Paniculati, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Rhizoma Corydalis, Radix Curcumae, Radix Glycyrrhizae Preparata are combined so that medicine Can liver and kidney tonifying, strengthening the tendons and bones, expelling wind and removing dampness, promoting blood circulation to restore menstrual flow, dispersing cold for relieving pain.With Herba Taxilli, Cortex Acanthopanciss, invigorating the liver and kidney in side, Bone and muscle strengthening, muscle is moistened in blood-nourishing, and the Cortex Eucommiae and Radix Dipsaci mutual reinforcement between are use, channels sootheing and network vessel quickening, invigorating the kidney and strengthening the bones, Herba Epimedii kidney invigorating and YANG supporting, raising immunity Power, five is monarch drug altogether.And Herba Taxilli joins Radix Clematidis and share, one dissipates a benefit, and nourishing blood to expel wind is wet, and Radix Clematidis walk in keep, no Cause in excessively walking to alter；Fructus Corni, Radix Morindae Officinaliss help Cortex Eucommiae tonifying liver to support kidney and support marrow honor muscle, and bone and muscle strengthening；Rhizoma Curculiginises help Herba Epimedii warming YANG to mend Kidney, for the sexual impotence cold sperm of insufficiency of kidney-YANG, decline of the fire from the gate of life, and kidney deficiency waist knee impotence, muscles and bones cold type of pain.Radix Clematidis helps Herba Taxilli to mend Liver and kidney, bone and muscle strengthening, nourishing blood to restore normal menstruation, above several altogether be ministerial drug, Radix Salviae Miltiorrhizae, Radix Achyranthis Bidentatae, Rhizoma Corydalis, Radix Curcumae etc. be adjuvant drug, Radix Glycyrrhizae Preparata Coordinating the actions of various ingredients in a prescription, for making medicine.The effect of liver and kidney tonifying, strengthening the tendons and bones, expelling wind and removing dampness, promoting blood circulation to restore menstrual flow, dispersing cold for relieving pain played altogether by all medicines.Logical Crossing drug regimen makes each efficacy of drugs produce synergism such that it is able to effectively treatment tethered cord syndrome.

The effect of medicine in the present invention：

Wherein：

Herba Taxilli：For Loranthaceae plant Herba Taxilli Taxillus chinensis（DC.）The dry zone leaf of Danser Stem branch.Nature and flavor：Bitter, sweet, flat.Return liver and kidney channel.Effect：Invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit, muscle, here side are moistened in blood-nourishing In be monarch drug, Herba Taxilli can mutually promote with Radix Clematidis compatibility, and Radix Clematidis can walk 12 warps, is to be apt to one of the person of walking in dispel-wind drug, Energy wind-damp dispelling, the meridian dredging, it is apt to control numb limbs and tense tendons pain, the rheumatalgia effect is significant to lower limb, Herba Taxilli invigorating the liver and kidney, strong muscle Bone, muscle is moistened in blood-nourishing.Two medicines share, one dissipate one benefit, blood-nourishing blood wind-damp dispelling, and Radix Clematidis walk in keep, be not excessively to walk to alter, right Body void rheumatic arthralgia person is suitable for, and Radix Clematidis joins Herba Taxilli not only can make invigorating the liver and kidney, and the effect of bone and muscle strengthening increases, and also has simultaneously The effect of nourishing blood to restore normal menstruation.

Cortex Acanthopanciss：Root bark for the drying of Araliaceae machaka acanthopanax gracilistyluses.Nature and flavor：Pungent, bitter, temperature.Return liver, kidney Warp.Effect：Wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, blood circulation and promoting silt, control anemofrigid-damp arthralgia, muscles and bones contraction is anxious, lumbago, traumatic injury impairment caused by overstrain, clinical Upper for the disease such as deficiency of the liver and kindey, soreness of waist and knee joint, powerless, the children's walking retardation in children of the flaccidity of feet and knees and normal and medicine such as Radix Achyranthis Bidentatae, Fructus Chaenomeliss, Radix Dipsaci is same With.

The Cortex Eucommiae：Dry bark for Eucommiaceae plant Cortex Eucommiae Eucommia ulmoides Oliv..Nature and flavor：Sweet, temperature.Return Liver and kidney channel.Effect：Liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, strengthen meridian and miscarriage prevention.

Radix Dipsaci：Root for Dipsacaceae herbaceos perennial Radix Dipsaci.Nature and flavor：Bitter；Pungent；Tepor.Return liver warp；Kidney channel. Effect：Invigorating the liver and kidney；Bone and muscle strengthening；Blood circulation regulating；Only metrorrhagia, all energy invigorating the liver and kidney of the Cortex Eucommiae and Radix Dipsaci, bone and muscle strengthening, for treating Liver and kidney not Foot, muscles and bones be not good for and arthromyodynia with the passing of time, Chang Xiangxu is use, but the simultaneous sexual impotence controlling insufficiency of kidney-YANG of the Cortex Eucommiae, frequent micturition etc., and Radix Dipsaci Injured can be continued, for traumatic injury, bruise and fracture etc. again.

Herba Epimedii：For Berberidaceae plant Herba Epimedii Epimedium brevicornum Maxim., Epimedium sagittatum Epimedium sagittatum （Sieb.et Zucc.）Maxim., E. Pubescens Epimedium pubescens Maxim., Epimedium wushanense Epimedium wushanense T.S.Ying or Herba Epimedii Epimedium koreanum The dry aerial parts of Nakai.Nature and flavor：Acrid, sweet, warm.Return liver and kidney channel.Effect：Kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.Herba Epimedii Extracting solution has Andrin-like action, can improve body's immunity, particularly kidney deficiency human immunity function is lowly had and changes Kind effect；There is significant inhibitory action in Herba Epimedii decoct test tube to polioviruses, in medicine and viruses contact 1 hour Interior, that is, show deactivation, other enterovirus also can be suppressed；Staphylococcus albus, staphylococcus aureuses are had significant Bacteriostasis, have slight inhibitory action to Nai Shi micrococcus catarrhalises, Diplococcus pneumoniae, hemophilus influenza.《This warp》：Main impotence is exhausted Wound, pains in the penis.Diuresis, physical strength profiting, Qiang Zhi.

Fructus Corni：For being dried to of Cornaceae plant Fructus Corni Cornus officinalis Sieb. et Zucc. Ripe sarcocarp.Nature and flavor：Sour, puckery, tepor.Return liver and kidney channel.Effect：Liver and kidney tonifying, essence astringing and desertion stemming.Clinically cure mainly and have a dizzy spell, ear Deaf tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding, Fructus Corni tepor is not dry, mend and not high, Can flat nourishing YIN sun, foster marrow honor muscle, commonly use by controlling deficiency of the liver and kindey, such as with the plain void of Liver and kidney, the feeling for author, Fructus Corni of soreness of waist flaccidity of the lower limbs The normal and medicine such as the Cortex Eucommiae, Radix Achyranthis Bidentatae is same to be used, with invigorating the liver and kidney, foster marrow honor muscle, and bone and muscle strengthening.

Rhizoma Curculiginises：Dry rhizome for amrallid Rhizoma Curculiginises Curculigo orchioides Gaertn..Nature and flavor：It is pungent, Heat；Poisonous.Return kidney,liver,spleen warp.Effect：Kidney-replenishing, bone and muscle strengthening, dispelling cold and dampness.Rhizoma Curculiginises aqueous extract has the work of excited sexual function With.Rhizoma Curculiginises play the role of to strengthen immunologic function.Herba Epimedii is pungent sweet warm in nature, and the property of warm-dryness syndrome is stronger, mends the fire of influencial family, and wind-damp dispelling is dredged Network effect is prominent, is longer than treatment rheumatic arthralgia, numb limbs and tense tendons etc., and Rhizoma Curculiginises are hot poisonous, and warm waist and knee, dispelling cold and dampness effect are prominent.Celestial Thatch and Herba Epimedii mutual reinforcement between are to use temperature male wind-supplying kidney, for the sexual impotence cold sperm of insufficiency of kidney-YANG, decline of the fire from the gate of life, and kidney deficiency waist knee impotence, Muscles and bones cold type of pain.

Radix Morindae Officinaliss：Root for dicotyledon medicine Maguireothamnus speciosus Radix Morindae Officinaliss.Nature and flavor：Pungent, sweet；Tepor.Return kidney channel, liver Warp.Effect：Reinforcing the kidney and supporting YANG, expelling wind and removing dampness, strengthening the tendons and bones.Often join Cortex Eucommiae etc. for the muscles and bones impotence of deficiency of the liver and kindey, lumbocrural pain, Or rheumatism lingering arthralgia and the deficient person of Liver and kidney, often join Radix Achyranthis Bidentatae etc.；This product can YANG invigorating benefit essence and bone and muscle strengthening, and can pungent-warm and remove wind Wet, therefore deficiency of the liver and kindey has rheumatism concurrently and lumbocrural pain person, use the most suitable.

Rhizoma Homalomenae：For Araeceae flat silk taro platymiscium Rhizoma Homalomenae Homalomena occulta（Lour.）Schott's Dry rhizome.Nature and flavor：Hardship, pungent, temperature.Return liver and kidney channel.Effect：Wind-damp dispelling, muscle reinforcing and bone strengthening, promoting blood circulation and stopping pain.

Folium Photiniae (Folium Photiniae serrulatae)：Leaf for rosaceous plant Chinese photinia PhotiniaserrulataLindl..Nature and flavor：Pungent, bitter, put down；Have little Poison.Return liver and kidney channel.Effect：Wind-dispelling, dredging collateral, kidney tonifying.

Radix Aconiti Lateralis Preparata：Processed goods for the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx. Aconitum carmichaeli Debx..Nature and flavor： Pungent, sweet, hot greatly；Poisonous.GUIXIN, kidney, spleen channel.Effect：Recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, dispelling cold and removing dampness.

Cortex Cinnamomi：Dry bark for canella Cortex Cinnamomi Cinnamomum cassia Presl.Nature and flavor：Pungent, sweet, greatly Heat.Return kidney, spleen, the heart, Liver Channel.Effect：Mends fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.

Radix Clematidis：Root and rhizome is dried for ranunculaceae plant Radix Clematidis, Clematis hexapetala or northeast clematis.Nature and flavor： Pungent, salty, temperature, poisonous.Return bladder warp.Effect：Expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, dissolving phlegm water, dissipate the hypochondriac lump.For rheumatic arthralgia, limbs Numb, joint stuffiness.All rheumatic arthralgia, apathy, no matter all available up and down, it is rheumatic arthralgia key medicine,《Medicineization justice》In Cloud：Radix Clematidis, property is suddenly anxious, is apt to walk and does not keep, the logical twelve channels and collateralses of a surname.Cure mainly wind, wet, expectorant is stopped up in stagnant meridians, cause into gout and walk through bone Section pain, or swollen or numb.Modern study confirms, Radix Clematidis contains Anemonin and Radix Pulsatillae alcohol, Saponin etc., has analgesia, resists Diuresis.Vinegar immersion has certain emollescence to fish bony spur, and makes local of flaccid muscles, promotes bony spur to come off.Decoct has bright Aobvious antibacterial action, all has to Gram-positive and negative bacterium, mycete compared with high inhibition effect, is equivalent to disappearing of Western medicine in this disease Scorching medicine, and antibacterial will not be made to produce drug resistance.

Radix Cynanchi Paniculati：For trailing plants section Cynanchum plant Radix Cynanchi Paniculati Cynanchum paniculatum（Bge.）Kitag. Root and rhizome is dried.Nature and flavor：Pungent, temperature.Return liver, stomach.Effect：Wind-dispelling removing dampness, antalgesic-antipruritic.

Radix Salviae Miltiorrhizae：For dicotyledon Labiatae, root and rhizome is dried.Nature and flavor：Hardship, is slightly cold, nontoxic.GUIXIN, Liver Channel.Work( Effect：Promoting blood circulation to restore menstrual flow, evacuation of pus granulation promoting, special regulating menstruation arteries and veins, reason iliacus is ached, and tissue regeneration promoting blood removes stagnant blood.

Radix Achyranthis Bidentatae：For amaranthaceous plant Radix Achyranthis Achyranthes aspera L. or Radix Achyranthis Bidentatae A. bidentata Blume （Wild species）Root.Nature and flavor：Picric acid, puts down.Enter the heart, liver, large intestine three warp.Effect：Promoting blood circulation to remove blood stasis, damp eliminating diuresis, heat-clearing and toxic substances removing.

Rhizoma Corydalis：Dry tuber for papaveraceae plant corydalis Corydalis yanhusuo W. T. Wang.Property Taste：Bitter, pungent, temperature；Return liver, the heart, stomach.Effect：Promoting blood circulation to remove blood stasis, promoting the circulation of QI to relieve pain, there are analgesia, calmness, syngignoscism.

Radix Curcumae：For zingiberaceous plant RADIX CURCUMAE Curcuma wenyujin Y. H. Chen et C. Ling, Rhizoma Curcumae Longae Curcuma longa L., Guangxi zedoary Curcuma kwangsiensis S. G. Lee et C. F. Liang or fluffy cowherb The dried root of art Curcuma phaeocaulis Val..Nature and flavor：Pungent, bitter, tremble with fear.Return liver, the heart, lung meridian.Effect：Circulation of qi promoting The stasis of blood, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice, removing heat from blood removing blood stasis with potent drugs.

Radix Glycyrrhizae Preparata：For dicotyledon pulse family Leguminosae Radix Glycyrrhizae Glycyrrhiza uralensisFisch., swollen Fruit Radix Glycyrrhizae G. inflataBat., or the root and rhizome of Glycyrrhiza glabra L. G. glabraL..Nature and flavor：Sweet, put down.Enter spleen, stomach, lung Warp.Effect：Benefiting qi and nourishing yin, activate yang multiple arteries and veins.

Medicine material consumption of the present invention is groped to summarize to draw, each raw material dosage is following in a large number through inventor Weight portion scope all has preferable curative effect：Herba Taxilli 15-25 part, Cortex Acanthopanciss 10-20 part, Cortex Eucommiae 15-25 part, Radix Dipsaci 15-25 Part, Herba Epimedii 15-25 part, Fructus Corni 10-20 part, Rhizoma Curculiginises 13-23 part, Radix Morindae Officinaliss 13-23 part, Rhizoma Homalomenae 10-20 part, Folium Photiniae (Folium Photiniae serrulatae) 10-20 part, Radix Aconiti Lateralis Preparata 7-17 part, Cortex Cinnamomi 4-14 part, Radix Clematidis 15-25 part, Radix Cynanchi Paniculati 13-23 part, Radix Salviae Miltiorrhizae 19-29 part, Radix Achyranthis Bidentatae 13-23 part, Rhizoma Corydalis 13-23 part, Radix Curcumae 10-20 part, Radix Glycyrrhizae Preparata 4-14 part.

Wherein it is preferably：20 parts of Herba Taxilli, 15 parts of Cortex Acanthopanciss, 20 parts of the Cortex Eucommiae, 20 parts of Radix Dipsaci, 20 parts of Herba Epimedii, Fructus Corni 15 parts, 18 parts of Rhizoma Curculiginises, 18 parts of Radix Morindae Officinaliss, 15 parts of Rhizoma Homalomenae, 15 parts of Folium Photiniae (Folium Photiniae serrulatae), 12 parts of Radix Aconiti Lateralis Preparata, 9 parts of Cortex Cinnamomi, 20 parts of Radix Clematidis, slowly 18 parts of long minister in ancient times, 24 parts of Radix Salviae Miltiorrhizae, 18 parts of Radix Achyranthis Bidentatae, 18 parts of Rhizoma Corydalis, 15 parts of Radix Curcumae, 9 parts of Radix Glycyrrhizae Preparata.

Medicine of the present invention can adopt the conventional fabrication process of Chinese medicine preparation, can be made into described on any pharmaceuticss Dosage form, such as pill, powder, tablet, capsule, granule, syrup, oral liquid etc..For example these crude drug can be ground into Powder, granularity is 80-120 mesh, gained fine powder input hybrid medicine blender is fully mixed, makes powder warm water and take after mixing it with water. Decocting can be used, through filtering to get filtrate, add preservative to make oral liquid；Decoction can also directly be taken if necessary.Acceptable Using its volatile oil of distillation extraction or its active component, various medically acceptable carriers can be added, make suitable, convenient Dosage form.

Medicine of the present invention has liver and kidney tonifying, strengthening the tendons and bones, expelling wind and removing dampness, promoting blood circulation to restore menstrual flow, effect of dispersing cold for relieving pain, and treats Imitate, cure rate is high, has no toxic side effect, taking convenience is cheap, directly enhances the life of tethered cord syndrome patient Quality, decreases stress and misery.According to clinical 200 patient view statistics, total using one course for the treatment of of medicine of the present invention Effective percentage 90%, two course for the treatment of total effective rates 98%.

Specific embodiment

Embodiment one, 15 parts of Herba Taxilli, 10 parts of Cortex Acanthopanciss, 15 parts of the Cortex Eucommiae, 15 parts of Radix Dipsaci, 15 parts of Herba Epimedii, Fructus Corni 10 Part, 13 parts of Rhizoma Curculiginises, 13 parts of Radix Morindae Officinaliss, 10 parts of Rhizoma Homalomenae, 10 parts of Folium Photiniae (Folium Photiniae serrulatae), 7 parts of Radix Aconiti Lateralis Preparata, 4 parts of Cortex Cinnamomi, 15 parts of Radix Clematidis, Xu are long 13 parts of minister in ancient times, 19 parts of Radix Salviae Miltiorrhizae, 13 parts of Radix Achyranthis Bidentatae, 13 parts of Rhizoma Corydalis, 10 parts of Radix Curcumae, 4 parts of Radix Glycyrrhizae Preparata.

Embodiment two, 20 parts of Herba Taxilli, 15 parts of Cortex Acanthopanciss, 20 parts of the Cortex Eucommiae, 20 parts of Radix Dipsaci, 20 parts of Herba Epimedii, Fructus Corni 15 Part, 18 parts of Rhizoma Curculiginises, 18 parts of Radix Morindae Officinaliss, 15 parts of Rhizoma Homalomenae, 15 parts of Folium Photiniae (Folium Photiniae serrulatae), 12 parts of Radix Aconiti Lateralis Preparata, 9 parts of Cortex Cinnamomi, 20 parts of Radix Clematidis, Xu are long 18 parts of minister in ancient times, 24 parts of Radix Salviae Miltiorrhizae, 18 parts of Radix Achyranthis Bidentatae, 18 parts of Rhizoma Corydalis, 15 parts of Radix Curcumae, 9 parts of Radix Glycyrrhizae Preparata.

Embodiment three, 25 parts of Herba Taxilli, 20 parts of Cortex Acanthopanciss, 25 parts of the Cortex Eucommiae, 25 parts of Radix Dipsaci, 25 parts of Herba Epimedii, Fructus Corni 20 Part, 23 parts of Rhizoma Curculiginises, 23 parts of Radix Morindae Officinaliss, 20 parts of Rhizoma Homalomenae, 20 parts of Folium Photiniae (Folium Photiniae serrulatae), 17 parts of Radix Aconiti Lateralis Preparata, 14 parts of Cortex Cinnamomi, 25 parts of Radix Clematidis, slowly 23 parts of long minister in ancient times, 29 parts of Radix Salviae Miltiorrhizae, 23 parts of Radix Achyranthis Bidentatae, 23 parts of Rhizoma Corydalis, 20 parts of Radix Curcumae, 14 parts of Radix Glycyrrhizae Preparata.

Clinical statisticses data that patient use of the present invention medicine is presented herein below：

First, physical data

In January, 2012 in May, 2013 accepts out-patient totally 400 for medical treatment, and patient is randomly divided into observation group and matched group, Wherein male 196, women 204, M-F 0.96:1, max age 62 years old, minimal ages 3 years old, 33 years old mean age, The shortest course of disease is 6 months, and the longest course of disease is 3.5 years, average course of disease 2.0 years, the items base such as two groups of patient ages, sex, courses of disease This data is essentially identical, no significant difference（P ＞ 0.05）.

2nd, diagnosis basis：

1st, pain dimensions are extensively it is impossible to be explained with single nervous lesion；

2nd, adult has obvious inducement before symptom；

3rd, often urinary tract infection in bladder and rectal dysfunction；

4th, sensorimotor obstacle progressive increases；

5th, there are different congenital malformations, or once had lumbosacral region history of operation；

6、MRI（Nuclear magnetic resonance, NMR）And (or) CT spinal canal myelography finds that the position of medullary cone exception and (or) filum terminale increase slightly.

3rd, Therapeutic Method：

1st, observation group, according to Medications Example two of the present invention, weighs crude drug（One daily dose）, filter and remove residue after decocting, early Evening services once, decoction being taken warmly.It is within 30th a course for the treatment of.

2nd, matched group is according to the optimal weight treating the medicine of proliferation arthritis of spine and preparation method thereof in CN01128976 Powder after amount proportioning preparation, one every time, sooner or later service once, be within 30th a course for the treatment of.

4th, efficacy assessment standard：

1st, cure：Limb activity is normal, fleshiness, and nervous system and lab testing are normal.

2nd, take a turn for the better：Limbs impotence weak takes a turn for the better, and symptom is improved, and nervous system and lab testing are normal.

3rd, do not heal：Limbs flaccidity is soft no to be improved.

5th, observation group's result statistics

Matched group result counts

Wherein：Total effective rate=cure rate+improvement rate

Take the situation of effect comparison of two groups of patients of two courses for the treatment of

It can be found that observation group, apparently higher than matched group, thus illustrates by contrasting the treatment total effective rate of two groups of patients, Chinese medicine of the present invention has good clinical effectiveness in treatment tethered cord syndrome, can effectively improve the cure rate for the treatment of, is worth Clinical practice is promoted.

Model case and curative effect：

Case one, patient Wei, man, at 9 years old age, to examine mother and to state lumbosacral region skin abnormality after birth, recent months Sensation child's walking is abnormal, and examining inspection and stating lower limb has pain, and lower limb power is weak, and with dysuria, MIR checks display spinal cord position Put and move down, circular cone deforms, give after patient takes embodiment one course for the treatment of of one treatment by Chinese herbs, limb activity is normal, and pain disappears, Urinate smooth, symptom disappears, cure.

Case two, patient Zhang, female, at 4 years old age, household carrys out diagnosis and treatment because discovery right side limbs are stiff and treats, and checks row Walk in dragging step shape, the right side, fully with landing, checks through MIR：Conus medullarises low level, lobe, waist 4 sacrum 3 vertebral body spina bifida.Diagnosis For tethered cord syndrome, after carrying out Release of Tethered Cord, give after patient takes embodiment two courses for the treatment of of two treatments by Chinese herbs, Limb activity is normal, and symptom disappears, and cures.

Case three, patient Liu, man, at 54 years old age, to examine and to state no obvious cause and left lower extremity walking disorder, heel Dare not land, conscious lower-left myasthenia of limbs, once in a while with urinary incontinence, MIR checks and is diagnosed as tethered cord syndrome, carries out spinal cord After tying lysis, give after patient takes embodiment two courses for the treatment of of three treatments by Chinese herbs, limb activity is normal, can normally arrange Urine, symptom disappears, and cures.

Claims (2)

1. a kind of Chinese medicine preparation treating tethered cord syndrome is it is characterised in that this Chinese medicine preparation is by following weight portion Medicine is made：Herba Taxilli 15-25 part, Cortex Acanthopanciss 10-20 part, Cortex Eucommiae 15-25 part, Radix Dipsaci 15-25 part, Herba Epimedii 15-25 part, mountain Fructus Evodiae 10-20 part, Rhizoma Curculiginises 13-23 part, Radix Morindae Officinaliss 13-23 part, Rhizoma Homalomenae 10-20 part, Folium Photiniae (Folium Photiniae serrulatae) 10-20 part, Radix Aconiti Lateralis Preparata 7-17 part, Cortex Cinnamomi 4-14 part, Radix Clematidis 15-25 part, Radix Cynanchi Paniculati 13-23 part, Radix Salviae Miltiorrhizae 19-29 part, Radix Achyranthis Bidentatae 13-23 part, Rhizoma Corydalis 13-23 Part, Radix Curcumae 10-20 part, Radix Glycyrrhizae Preparata 4-14 part.

2. the Chinese medicine preparation for the treatment of tethered cord syndrome according to claim 1 is it is characterised in that by following weight portion Medicine make：20 parts of Herba Taxilli, 15 parts of Cortex Acanthopanciss, 20 parts of the Cortex Eucommiae, 20 parts of Radix Dipsaci, 20 parts of Herba Epimedii, 15 parts of Fructus Corni, Rhizoma Curculiginises 18 parts, 18 parts of Radix Morindae Officinaliss, 15 parts of Rhizoma Homalomenae, 15 parts of Folium Photiniae (Folium Photiniae serrulatae), 12 parts of Radix Aconiti Lateralis Preparata, 9 parts of Cortex Cinnamomi, 20 parts of Radix Clematidis, 18 parts of Radix Cynanchi Paniculati, 24 parts of Radix Salviae Miltiorrhizae, 18 parts of Radix Achyranthis Bidentatae, 18 parts of Rhizoma Corydalis, 15 parts of Radix Curcumae, 9 parts of Radix Glycyrrhizae Preparata.