CN104173560A - Traditional Chinese medicine composition for preventing and treating salpingitis of laying hen and preparation method of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for preventing and treating salpingitis of laying hen and preparation method of traditional Chinese medicine composition Download PDFInfo
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- CN104173560A CN104173560A CN201410388046.5A CN201410388046A CN104173560A CN 104173560 A CN104173560 A CN 104173560A CN 201410388046 A CN201410388046 A CN 201410388046A CN 104173560 A CN104173560 A CN 104173560A
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Abstract
The invention relates to a traditional Chinese medicine composition for preventing and treating salpingitis of a laying hen. The traditional Chinese medicine composition is an oral solution prepared from codonopsis pilosula, rhizoma atractylodis macrocephalae, angelica sinensis, ligusticum wallichii, astragalus membranaceus, cortex acanthopanacis, radix rehmanniae preparata, cinnamon, peach kernel, flos carthami and agrimonia pilosa ledeb. The composition is prepared by the following steps: (1) grinding the traditional Chinese medicinal materials to 20-60 meshes, weighing according to the prescribed amount, and mixing in a three-dimensional manner to obtain traditional Chinese medicine powder; (2) putting the mixed traditional Chinese medicine powder into an extraction pot, adding 100-200 parts of water, and decocting for 2-12 hours; (3) filtering to remove decoction dregs, and keeping filtrate for later use; (4) putting the decoction dregs into the extraction pot once again, adding 100-200 parts of water, and decocting for 2-12 hours; (5) filtering to remove decoction dregs, and combining liquid and the first extracted liquid; (6) concentrating at 30-100 DEG C in reduced pressure until the volume of the concentrate is 10-50 percent of the original volume, filtering to remove dregs, and filling into bottles (250ml/bottle). The traditional Chinese medicine composition is capable of effectively preventing and treating salpingitis of the laying hen, has a cure rate of over 90 percent, and has the effects of nourishing qi and blood, activating blood circulation to remove stasis, astringing and stopping bleeding, and nourishing yin and warming kidney.
Description
Technical field
The invention belongs to herbal medicine formulation art, especially a kind of Chinese medicine composition of preventing and treating hens salpingitis and preparation method thereof.
Background technology
Salpingitis is chicken, and particularly a kind of commonly encountered diseases of laying hen, take fallopian tube inflammation clinically as feature, when serious, follicle distortion, congested, hemorrhage, is bronzing or taupe, even breaks, the egg yolk liquid breaking in abdominal cavity, taste stench, follicle shrinkage sometimes, shape is irregular, be golden yellow or brown, tarnish, when the state of an illness is slightly long, intestinal adhesion, fallopian tube has the cheesy thing of yellow-white.Cause of disease more complicated is to threaten one of poultry husbandry sound development frequently-occurring disease.
Cardinal symptom comprises 1 clinically, all are normal for chicken group outward appearance, but lays eggs without peak period.2, sick cockscomb is thick, scarlet, and abdominal part is sagging.3, the blister that differs in size in fallopian tube, large has more than 600 milliliter, and little has several milliliters. and hydrops is refrigerant, colourless, transparent, tasteless liquid. and some chicken salpingo is without hydrops, but has cecum or uterine tube stegnosis or without fallopian tube mouth.4, most of sick chicken follicular developments are normal. and the chicken intraperitoneal having has 6-7 ripe ovum, but there is no the fallopian tube of complete function, cannot lay eggs, and other organs are without extremely.Sick fowl main manifestations is that pain is uneasy, on its eggshell of the egg of output often with bloodstain.In fallopian tube, often discharge yellow, white pus sample secretions, pollute anus around and feather below, the difficulty of laying eggs.Along with the development of the state of an illness, sick fowl starts heating, and after heat is moved back, painful uneasy, stands transfixed to the ground, and two wings are sagging, and disorderly, some abdominal paries, by ground or lethargy, can cause peritonitis, or salpingorrhexis cause yolk peritonitis to feather pine when inflammation spreads to abdominal cavity.
At present treatment salpingitis mainly relies on heavy dose of antibiotic that uses, conventional as amoxicillin, ampicillin etc.But clinical therapeutic efficacy is not remarkable, especially substantially invalid to soft-shelled egg, Rhizoma Euonymus egg, can produce the risk of antibiotic remains in egg simultaneously.Therefore, develop a kind of medicine that can effectively prevent and treat hens salpingitis and become the task of top priority.
Summary of the invention
The problem to be solved in the present invention is: overcome the deficiencies in the prior art, a kind of good effect, no drug residue, safe and reliable laying hen Chinese medicine composition are provided.
Another technical problem that the present invention will solve is: a kind of Chinese medicine formula of preventing and treating hens salpingitis is provided.
Another technical problem that the present invention will solve is: the preparation method of above-mentioned laying hen with the oral liquid formulations of Chinese medicine composition is provided.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of Chinese medicine composition of preventing and treating hens salpingitis, is prepared from by the raw material of following mass fraction: Radix Codonopsis 10-20, Rhizoma Atractylodis Macrocephalae 10-20, Radix Angelicae Sinensis 20-30, Rhizoma Chuanxiong 10-20, Radix Astragali 10-20, Cortex Acanthopancis 10-20, Radix Rehmanniae Preparata 20-30, Cortex Cinnamomi 20-30, Semen Persicae 10-20, Flos Carthami 10-20, Herba Agrimoniae 10-20.
Further, the mass fraction of the optimum feed stock of this Chinese medicine composition is as follows:
Radix Codonopsis 20, the Rhizoma Atractylodis Macrocephalae 20, Radix Angelicae Sinensis 30, Rhizoma Chuanxiong 20, the Radix Astragali 20, Cortex Acanthopancis 15, Radix Rehmanniae Preparata 20, Cortex Cinnamomi 20, Semen Persicae 10, Flos Carthami 20, Herba Agrimoniae 20.
Further, this Chinese medicine composition is the various conventional extract oral medicine dosage form that contains or do not contain pharmaceutic adjuvant.
Further, described preparation can be oral liquid, and now the input amount of water is 200-400 part.
Further, the preparation method of the oral liquid formulations of said composition is: (1) is broken to 20-60 order by Chinese medicine powder, by formula ratio, takes, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder is put in extraction pot, added 100-200 times of water gaging and boil 2-12 hour; (3) remove by filter medicinal residues, gained filtrate is kept somewhere standby; (4) medicinal residues are put in extraction pot again, added 100-200 times of water gaging and boil 2-12 hour; (5) remove by filter medicinal residues, gained liquid and extracting liq merging for the first time; (6) 30-100 ℃ is evaporated to original volume 10%-50%, filter cleaner fill, every bottle of 250ml.
Advantage and good effect that the present invention has are:
(1) the present invention is according to tcm theory, and science compatibility has retained the combined effect of Chinese medicinal formulae determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, through clinical verification determined curative effect, is a kind of green veterinary drug of nuisanceless no drug residue.
(2) Chinese medicine composition provided by the present invention can effectively be prevented and treated hens salpingitis, to the cure rate of hens salpingitis, can reach more than 90%.This prescription has the effect of qi and blood tonifying, blood circulation promoting and blood stasis dispelling, astringing to arrest bleeding, YIN nourishing warming the kidney.Drug resistance and the residue problem of medicine in egg of chemicals have been avoided simultaneously.
(3) pharmacology of each raw material of Chinese medicine of the present invention is:
Radix Codonopsis: invigorating the spleen and replenishing QI, nourishing blood to promote the production of body fluid.
The Rhizoma Atractylodis Macrocephalae: invigorating the spleen and benefiting QI, dampness diuretic.
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation.
Rhizoma Chuanxiong: promoting flow of QI and blood.
The Radix Astragali: benefiting QI for strengthening the superficies, detoxification evacuation of pus, expelling pus and promoting granulation.
Cortex Acanthopancis: replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization.
Radix Rehmanniae Preparata: nourishing YIN and clearing away heat; Removing heat from blood is enriched blood.
Cortex Cinnamomi: mend fire supporing yang, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.
Semen Persicae: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.
Flos Carthami: the latus rectum of invigorating blood circulation, eliminating stasis to stop pain.
Herba Agrimoniae: astringing to arrest bleeding.
Among formula, Radix Codonopsis, Radix Astragali invigorating the spleen and replenishing QI, the consolidating superficial resistance that nourishes blood, Papillary can make the complete foot of health QI and blood, effectively improves disease fowl body immunity, recovers human body immune system function, improves defending and fighting against diseases ability.Radix Angelicae Sinensis, Rhizoma Chuanxiong, Semen Persicae, Flos Carthami, Cortex Cinnamomi five kinds of Chinese medicine share can play promoting flow of QI and blood, the effect of the blood stasis dispelling of stimulating the menstrual flow.The diseases such as the laying hen follicle hyperemia causing for blood stasis due to qi deficiency, swelling have definite therapeutic effect.Herba Agrimoniae astringing to arrest bleeding can effectively treat fallopian tube and follicle is hemorrhage.Cortex Acanthopancis replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization.Effectively regulate sick fowl balance, appetite stimulator, promotes the rehabilitation of disease fowl.Radix Rehmanniae Preparata nourishing YIN and clearing away heat, improves estrogen secretion level, can accelerate the rehabilitation of disease fowl on the one hand, can improve the level of laying eggs on the other hand, extends laying period.Rhizoma Atractylodis Macrocephalae infiltration dampness removing can effectively be got rid of pus in follicle and fallopian tube.
The specific embodiment
Below by specific embodiment, the invention will be further described, and following examples are descriptive, is not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
Prevent and treat a Chinese medicine oral liquid for hens salpingitis, each raw material of Chinese medicine and weight thereof respectively: Radix Codonopsis 20, the Rhizoma Atractylodis Macrocephalae 20, Radix Angelicae Sinensis 30, Rhizoma Chuanxiong 20, the Radix Astragali 20, Cortex Acanthopancis 15, Radix Rehmanniae Preparata 20, Cortex Cinnamomi 20, Semen Persicae 10, Flos Carthami 20, Herba Agrimoniae 20.Its preparation method is: (1) is broken to 60 orders by Chinese medicine powder, by formula ratio, takes, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder is put in extraction pot, added 200 parts of decocting in water 10 hours; (3) remove by filter medicinal residues, gained filtrate is kept somewhere standby; (4) medicinal residues are put in extraction pot again, added 200 parts of decocting in water 10 hours; (5) remove by filter medicinal residues, gained liquid and extracting liq merging for the first time; (6) 65 ℃ are evaporated to original volume 30%, filter cleaner fill, every bottle of 250ml.
Embodiment 2
Prevent and treat a Chinese medicine oral liquid for hens salpingitis, each raw material of Chinese medicine and weight thereof respectively: Radix Codonopsis 10, the Rhizoma Atractylodis Macrocephalae 15, Radix Angelicae Sinensis 20, Rhizoma Chuanxiong 20, the Radix Astragali 15, Cortex Acanthopancis 10, Radix Rehmanniae Preparata 15, Cortex Cinnamomi 15, Semen Persicae 10, Flos Carthami 20, Herba Agrimoniae 20.Its preparation method is: (1) is broken to 60 orders by Chinese medicine powder, by formula ratio, takes, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder is put in extraction pot, added 150 parts of decocting in water 10 hours; (3) remove by filter medicinal residues, gained filtrate is kept somewhere standby; (4) medicinal residues are put in extraction pot again, added 150 parts of decocting in water 10 hours; (5) remove by filter medicinal residues, gained liquid and extracting liq merging for the first time; (6) 65 ℃ are evaporated to original volume 30%, filter cleaner fill, every bottle of 250ml.
Embodiment 3
Prevent and treat a Chinese medicine oral liquid for hens salpingitis, each raw material of Chinese medicine and weight thereof respectively: Radix Codonopsis 15, the Rhizoma Atractylodis Macrocephalae 20, Radix Angelicae Sinensis 15, Rhizoma Chuanxiong 10, the Radix Astragali 20, Cortex Acanthopancis 10, Radix Rehmanniae Preparata 20, Cortex Cinnamomi 10, Semen Persicae 15, Flos Carthami 20, Herba Agrimoniae 20.Its preparation method is: (1) is broken to 60 orders by Chinese medicine powder, by formula ratio, takes, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder is put in extraction pot, added 150 parts of decocting in water 10 hours; (3) remove by filter medicinal residues, gained filtrate is kept somewhere standby; (4) medicinal residues are put in extraction pot again, added 150 parts of decocting in water 10 hours; (5) remove by filter medicinal residues, gained liquid and extracting liq merging for the first time; (6) 65 ℃ are evaporated to original volume 30%, filter cleaner fill, every bottle of 250ml.
Clinical trial
Experiment 1:
Breeding layer chicken field, Sichuan, 50000 of breeding stocks, 5000 of salpingitis morbidities.Clinical manifestation is fervescence, and spirit is depressed, and blood egg, appears in the difficulty of laying eggs, pain, and white pus shape pollutant appear around in anus.Clinical diagnosis is salpingitis.To wherein 3000 use the obtained products of embodiment 1.Every bottle is watered 150 kilograms, once a day, treats three days.Medication second day symptom obviously alleviates, and depletion of blood egg occurs, within the 3rd day, removes, and jumpbogroup is cured, and lays eggs normal, discontinues medication.Lay eggs two days later and return to normal level.Cure rate reaches 98.5%.Another 2000 are used amoxicillin to coordinate hemorrhage carbazochrome salicylate, treat five days.The 3rd day starts onset, and part laying hen still has blood egg, and within the 5th day, jumpbogroup is cured substantially, cure rate 85.2%.
Experimental results show that the treatment salpingitis medicine that amoxicillin that the obtained product curative effect of embodiment 1 is obviously better than commonly using is on the market main constituent.
Experiment 2:
Breeding layer chicken field, Jilin, northeast, 45000 of breeding stocks, 1500 of salpingitis morbidities.Clinical manifestation is the difficulty of laying eggs, pain, occurs blood egg, Rhizoma Euonymus, soft-shelled egg.Clinical diagnosis is salpingitis.Wherein 1000 are used the obtained product of embodiment 1.75 kilograms of every bottle of spice amounts, once a day, treat three days.Medication second day symptom obviously alleviates, basic depletion of blood egg, Rhizoma Euonymus egg and soft-shelled egg.The 3rd day, jumpbogroup was cured, and laid eggs normal.Cure rate reaches 98%.Another 500 are used antibiotics ampicillin to share carbazochrome salicylate, cod-liver oil, treat five days.Within the 3rd day, start onset, within the 5th day, jumpbogroup is cured, cure rate 73%.
Experimental results show that the treatment salpingitis medicine that ampicillin that the obtained product curative effect of embodiment 1 is obviously better than commonly using is on the market main constituent.
The above, be only preferred embodiments of the present invention, is illustrative rather than determinate, can list several embodiment according to limited range, therefore in the variation and the modification that do not depart under general plotting of the present invention, within should belonging to protection scope of the present invention.
Claims (9)
1. a Chinese medicine composition of preventing and treating hens salpingitis, is characterized in that: the raw material by following mass fraction is prepared from: Radix Codonopsis 10-20, Rhizoma Atractylodis Macrocephalae 10-20, Radix Angelicae Sinensis 20-30, Rhizoma Chuanxiong 10-20, Radix Astragali 10-20, Cortex Acanthopancis 10-20, Radix Rehmanniae Preparata 20-30, Cortex Cinnamomi 20-30, Semen Persicae 10-20, Flos Carthami 10-20, Herba Agrimoniae 10-20.
2. the Chinese medicine composition of control hens salpingitis according to claim 1, is characterized in that: the mass fraction of optimum feed stock is as follows:
Radix Codonopsis 20, the Rhizoma Atractylodis Macrocephalae 20, Radix Angelicae Sinensis 30, Rhizoma Chuanxiong 20, the Radix Astragali 20, Cortex Acanthopancis 15, Radix Rehmanniae Preparata 20, Cortex Cinnamomi 20, Semen Persicae 10, Flos Carthami 20, Herba Agrimoniae 20.
3. the Chinese medicine composition of control hens salpingitis according to claim 1 and 2, is characterized in that: this Chinese medicine composition is the various conventional extract oral medicine dosage form that contains or do not contain pharmaceutic adjuvant.
4. the Chinese medicine composition of control hens salpingitis according to claim 3, is characterized in that: described preparation can be oral liquid, and now the input amount of water is 200-400 part.
5. a method of preparing the Chinese medicine composition of control hens salpingitis as claimed in claim 4, is characterized in that: preparation method is: (1) is broken to certain order number by Chinese medicine powder, by formula ratio, takes, and three-dimensional hybrid obtains Chinese medicine powder; (2) mixed Chinese medicine powder, water are put in extraction pot, decocting in water extracts certain hour; (3) filter and collect filtrate; (4) medicinal residues, water are put in extraction pot again, decocting in water extracts certain hour; (5) filter and collect filtrate, gained liquid and extracting liq merging for the first time; (6) be evaporated at a certain temperature certain volume, fill, gets product.
6. the preparation method of the Chinese medicine composition of control hens salpingitis according to claim 5, is characterized in that: described pulverizing order number is 20-60 order.
7. the preparation method of the Chinese medicine composition of control hens salpingitis according to claim 5, is characterized in that: twice decocting in water extraction time is 2-12 hour.
8. the preparation method of the Chinese medicine composition of control hens salpingitis according to claim 5, is characterized in that: described concentrating under reduced pressure temperature is 30-100 ℃.
9. the preparation method of the Chinese medicine composition of control hens salpingitis according to claim 5, is characterized in that: described concentrating under reduced pressure volume is original volume 10%-50%.
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104489406A (en) * | 2014-12-29 | 2015-04-08 | 济南和美华饲料有限公司 | Premixed feed for promoting body growth of laying hen in brooding later period |
| CN106306545A (en) * | 2016-08-30 | 2017-01-11 | 广西园丰牧业有限公司 | Feed for treating chicken salpingitis |
| CN109528965A (en) * | 2019-01-23 | 2019-03-29 | 河南焱地农牧科技有限公司 | Ensure the novel traditional Chinese medicine for livestock preparation and preparation method thereof of birds genital tract health |
| CN110946983A (en) * | 2020-01-08 | 2020-04-03 | 河南大德广动物药业有限公司 | A Chinese medicinal composition for treating salpingitis of egg-laying fowl, and its preparation method |
| CN111990533A (en) * | 2020-09-21 | 2020-11-27 | 天津纳尔生物科技有限公司 | Fermented eucommia ulmoides leaf extract and application thereof in preparation of chicken feed |
| CN115227761A (en) * | 2022-07-28 | 2022-10-25 | 郑佰有 | Traditional Chinese medicine composition for treating chicken hydrosalpinx disease and preparation method thereof |
-
2014
- 2014-08-05 CN CN201410388046.5A patent/CN104173560A/en active Pending
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| 刘玉成: "《赐嗣：不孕症诊疗理论与实践》", 31 August 2007, 军事医学科学出版社 * |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104489406A (en) * | 2014-12-29 | 2015-04-08 | 济南和美华饲料有限公司 | Premixed feed for promoting body growth of laying hen in brooding later period |
| CN106306545A (en) * | 2016-08-30 | 2017-01-11 | 广西园丰牧业有限公司 | Feed for treating chicken salpingitis |
| CN109528965A (en) * | 2019-01-23 | 2019-03-29 | 河南焱地农牧科技有限公司 | Ensure the novel traditional Chinese medicine for livestock preparation and preparation method thereof of birds genital tract health |
| CN110946983A (en) * | 2020-01-08 | 2020-04-03 | 河南大德广动物药业有限公司 | A Chinese medicinal composition for treating salpingitis of egg-laying fowl, and its preparation method |
| CN111990533A (en) * | 2020-09-21 | 2020-11-27 | 天津纳尔生物科技有限公司 | Fermented eucommia ulmoides leaf extract and application thereof in preparation of chicken feed |
| CN115227761A (en) * | 2022-07-28 | 2022-10-25 | 郑佰有 | Traditional Chinese medicine composition for treating chicken hydrosalpinx disease and preparation method thereof |
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Application publication date: 20141203 |