CN104173519B - 一种治疗新生儿尿布皮炎的中药粉剂 - Google Patents
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Abstract
本发明公开了一种治疗新生儿尿布皮炎的中药粉剂。祖国医学认为尿布疹多因湿、热、毒所致，治宜清热解毒、燥湿化瘀、除腐生肌、消炎止痒。为此，本发明选择中药伤寒草、抱树莲、红毛走马胎、黄花母、算盘子根、水团花、菜豆树、黄葵、七星剑、绣线菊叶，制成粉剂敷于患部，经临床试验，总有效率93.3％，明显优于对照组的84.4％，而且无副作用。
Description
技术领域
本发明涉及一种中药组合物，尤其涉及一种治疗新生儿尿布皮炎的中药粉剂。
背景技术
新生儿尿布皮炎俗称新生儿红臀，是发生在新生儿臀部的凸面、肛门周围、阴囊(或阴唇)及股内侧等部位的局限性皮肤病，主要表现为肛门周围、会阴部皮肤发红，继而出现红斑、丘疹，以后融合成片，较重时发生表皮脱落或糜烂。新生儿常因红臀痒、痛、灼热的刺激而烦躁、哭闹、睡卧不安。红臀时若皮肤破损，细菌易繁殖造成局部感染，严重时引起败血症。因此，新生儿尿布皮炎重在预防，发现臀部发红、皮疹、糜烂时能及时有效的治疗。常用的治疗方法主要是扑爽身粉，而爽身粉中的滑石粉含有不可分离的铅，铅进入婴儿体内不能很快被排泄。当长期蓄积于人体时，就会危害神经、造血系统及消化系统，严重影响婴儿的智力和身体发育。当炎症较为严重时西医还会使用抗生素或抗真菌剂，这无疑对新生儿幼小的身体带来沉重的负担和不可避免的副作用。申请人利用中药制成粉剂敷于患处，不但可以消毒杀菌，还可以收敛皮肤粘膜及溃疡，使局部干燥、滑爽，治疗效果非常显著，且价格便宜，外用无毒副作用，操作简便，值得临床推广。
发明内容
本发明的目的是提供一种治疗新生儿尿布皮炎的中药粉剂。祖国医学认为尿布疹多因湿、热、毒所致，治宜清热解毒、燥湿化瘀、除腐生肌、消炎止痒。
本发明的目的是通过以下技术方案实现的，该治疗新生儿尿布皮炎的中药粉剂由以下重量份的中药制成：伤寒草5-9份、抱树莲5-7份、红毛走马胎3-6份、黄花母3-5份、算盘子根8-10份、水团花5-10份、菜豆树5-8份、黄葵3-5份、七星剑6-10份、绣线菊叶6-9份。
优选的，伤寒草7份、抱树莲6份、红毛走马胎5份、黄花母4份、算盘子根9份、水团花7份、菜豆树6份、黄葵4份、七星剑8份、绣线菊叶6.5份。
制备方法洗净烘干，用粉碎机粉碎成细小粉末(120目)。
方中：伤寒草清热除湿、解毒；抱树莲清热利湿、解毒杀虫；红毛走马胎清热利湿、活血化瘀；黄花母清热利湿、活血排脓；算盘子根清热利湿、凉血、解毒；水团花清热利湿、止血、生肌、消肿、定痛；菜豆树清热解毒、散瘀止痛；黄葵解毒消肿、排脓止痛；七星剑祛风止痒、攻毒、消疮肿；绣线菊叶去腐生肌、排脓消肿。
临床资料
1、一般资料 选择2010年1～12月我院新生儿尿布皮炎患儿90例。随机分为治疗组和对照组。治疗组男25例，女20例，皮损为单纯红斑23例，红斑伴轻度糜烂15例，伴大面积糜烂或溃疡7例。对照组男27例，女18例，皮损为单纯红斑22例，红斑伴有轻度糜烂15例，伴大面积糜烂或溃疡8例。2组年龄、性别、体质量、喂养方式及病情等方面比较差异无统计学意义(P＞0.05)，具有可比性。
2、诊断标准 (1)皮损初发为轻度潮红、肿胀、丘疹、水疱、糜烂、脓疱。(2)好发部位：接触尿布的部位，如臀部凸隆部、外阴部、下腹部和股内侧等。(3)多发于乳婴儿，冬重夏轻。
3、治疗及护理方法 ①对照组：应用传统的方法，温水洗净臀部，然后用吸水性强的软棉布轻轻拭干臀部的水分，敷上新生儿爽身粉。②治疗组：称取伤寒草7g、抱树莲6g、红毛走马胎5g、黄花母4g、算盘子根9g、水团花7g、菜豆树6g、黄葵4g、七星剑8g、绣线菊叶6.5g。洗净烘干，用粉碎机粉碎成细小粉末(120目)。常规洗干净臀部后拭干臀部，将药粉敷于患处，使患处皮肤裸露10分钟，保持干燥，5-7d为一个疗程。
在治疗的过程中，加强基础护理，保持臀部清洁、干燥，擦洗时动作应轻柔，便后一定用温水洗净、擦干。
4、疗效标准 治疗1个疗程后进行评价。治愈：病损处皮肤完全恢复正常，无糜烂及渗出；显效：用药后病损皮肤愈合50％以上或糜烂、渗出消失；有效：病损皮肤愈合25％以上或糜烂、渗出明显减少；无效：病变范围及程度无明显减轻或加重。治愈、显效加有效为总有效。
5、治疗结果 两组患者治疗一个疗程后统计疗效，治疗组45例患者，其中治愈15例(33.3％)，显效18例(40％)，有效9例(20％)，无效3例(6.7％)，总有效率93.3％。对照组45例患者，其中治愈9例(20％)，显效11例(24.4％)，有效18例(40％)，无效7例(15.6％)，总有效率84.4％。所有患者在治疗前后，呼吸、心率、脉率、血压，血，尿，粪常规，肝肾功能及心电图均无明显异常变化，观察期间均未出现不良反应。
具体实施方式
实施例一：称取伤寒草7g、抱树莲6g、红毛走马胎5g、黄花母4g、算盘子根9g、水团花7g、菜豆树6g、黄葵4g、七星剑8g、绣线菊叶6.5g，将上述中药材洗净烘干，用粉碎机粉碎成细小粉末(120目)。
实施例二：称取伤寒草9g、抱树莲5g、红毛走马胎6g、黄花母5g、算盘子根10g、水团花5g、菜豆树8g、黄葵3g、七星剑10g、绣线菊叶9g，将上述中药材洗净烘干，用粉碎机粉碎成细小粉末(120目)。
实施例三：称取伤寒草5g、抱树莲7g、红毛走马胎3g、黄花母3g、算盘子根8g、水团花10g、菜豆树5g、黄葵5g、七星剑6g、绣线菊叶6g，将上述中药材洗净烘干，用粉碎机粉碎成细小粉末(120目)。
Claims (2)
1.一种治疗新生儿尿布皮炎的中药粉剂，其特征在于该中药粉剂由以下重量份的中药制成：伤寒草5-9份、抱树莲5-7份、红毛走马胎3-6份、黄花母3-5份、算盘子根8-10份、水团花5-10份、菜豆树5-8份、黄葵3-5份、七星剑6-10份、绣线菊叶6-9份。
2.如权利要求1所述的一种治疗新生儿尿布皮炎的中药粉剂，其特征在于该中药粉剂由以下重量份的中药制成：伤寒草7份、抱树莲6份、红毛走马胎5份、黄花母4份、算盘子根9份、水团花7份、菜豆树6份、黄葵4份、七星剑8份、绣线菊叶6.5份。
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| CN103393813A (zh) * | 2013-07-31 | 2013-11-20 | 成都泓泰生物制品有限公司 | 治疗烧伤烫伤兼治化脓性感染、开放性外伤的纯中药制剂 |
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| CN103041173A (zh) * | 2012-12-31 | 2013-04-17 | 青岛华仁信息技术开发有限公司 | 一种治疗皮炎、湿疹的中药外用制剂及其制备方法 |
| CN103393813A (zh) * | 2013-07-31 | 2013-11-20 | 成都泓泰生物制品有限公司 | 治疗烧伤烫伤兼治化脓性感染、开放性外伤的纯中药制剂 |
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| 自拟解毒方治疗新生儿尿布皮炎38例;韩蕾等;《中国中医急症》;20050531;第14卷(第05期);第461页 * |
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