CN104172151A - Seal oil soft capsules containing coenzyme Q10 - Google Patents
Seal oil soft capsules containing coenzyme Q10 Download PDFInfo
- Publication number
- CN104172151A CN104172151A CN201410297589.6A CN201410297589A CN104172151A CN 104172151 A CN104172151 A CN 104172151A CN 201410297589 A CN201410297589 A CN 201410297589A CN 104172151 A CN104172151 A CN 104172151A
- Authority
- CN
- China
- Prior art keywords
- seal oil
- coenzyme
- dha
- soft capsules
- dpa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title claims abstract description 19
- 239000007901 soft capsule Substances 0.000 title claims abstract description 11
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 title abstract 5
- 235000017471 coenzyme Q10 Nutrition 0.000 title abstract 5
- 229940110767 coenzyme Q10 Drugs 0.000 title abstract 5
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 14
- 235000020673 eicosapentaenoic acid Nutrition 0.000 claims abstract description 12
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 7
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 7
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 7
- 229940046009 vitamin E Drugs 0.000 claims abstract description 7
- 239000011709 vitamin E Substances 0.000 claims abstract description 7
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 claims abstract description 6
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 claims abstract description 6
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N dodecahydrosqualene Natural products CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229940031439 squalene Drugs 0.000 claims abstract description 6
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 claims abstract description 6
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims abstract description 5
- 229960005135 eicosapentaenoic acid Drugs 0.000 claims abstract description 5
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims abstract description 5
- 239000002775 capsule Substances 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 239000002994 raw material Substances 0.000 claims description 3
- PIFPCDRPHCQLSJ-WYIJOVFWSA-N 4,8,12,15,19-Docosapentaenoic acid Chemical compound CC\C=C\CC\C=C\C\C=C\CC\C=C\CC\C=C\CCC(O)=O PIFPCDRPHCQLSJ-WYIJOVFWSA-N 0.000 claims description 2
- PIFPCDRPHCQLSJ-UHFFFAOYSA-N Clupanodonic acid Natural products CCC=CCCC=CCC=CCCC=CCCC=CCCC(O)=O PIFPCDRPHCQLSJ-UHFFFAOYSA-N 0.000 claims description 2
- 235000021290 n-3 DPA Nutrition 0.000 claims description 2
- YUFFSWGQGVEMMI-JLNKQSITSA-N (7Z,10Z,13Z,16Z,19Z)-docosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCCCC(O)=O YUFFSWGQGVEMMI-JLNKQSITSA-N 0.000 abstract description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract description 8
- 230000002526 effect on cardiovascular system Effects 0.000 abstract description 5
- 208000024172 Cardiovascular disease Diseases 0.000 abstract description 4
- 235000021294 Docosapentaenoic acid Nutrition 0.000 abstract description 4
- 108010010803 Gelatin Proteins 0.000 abstract description 4
- 208000026106 cerebrovascular disease Diseases 0.000 abstract description 4
- 229920000159 gelatin Polymers 0.000 abstract description 4
- 239000008273 gelatin Substances 0.000 abstract description 4
- 235000019322 gelatine Nutrition 0.000 abstract description 4
- 235000011852 gelatine desserts Nutrition 0.000 abstract description 4
- 235000011187 glycerol Nutrition 0.000 abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 4
- 239000000463 material Substances 0.000 abstract description 3
- 235000021122 unsaturated fatty acids Nutrition 0.000 abstract description 3
- 150000004670 unsaturated fatty acids Chemical class 0.000 abstract description 3
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 210000004413 cardiac myocyte Anatomy 0.000 abstract description 2
- 208000024891 symptom Diseases 0.000 abstract description 2
- MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 abstract 2
- 235000020669 docosahexaenoic acid Nutrition 0.000 abstract 2
- DVSZKTAMJJTWFG-SKCDLICFSA-N (2e,4e,6e,8e,10e,12e)-docosa-2,4,6,8,10,12-hexaenoic acid Chemical compound CCCCCCCCC\C=C\C=C\C=C\C=C\C=C\C=C\C(O)=O DVSZKTAMJJTWFG-SKCDLICFSA-N 0.000 abstract 1
- GZJLLYHBALOKEX-UHFFFAOYSA-N 6-Ketone, O18-Me-Ussuriedine Natural products CC=CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O GZJLLYHBALOKEX-UHFFFAOYSA-N 0.000 abstract 1
- 229940090949 docosahexaenoic acid Drugs 0.000 abstract 1
- KAUVQQXNCKESLC-UHFFFAOYSA-N docosahexaenoic acid (DHA) Natural products COC(=O)C(C)NOCC1=CC=CC=C1 KAUVQQXNCKESLC-UHFFFAOYSA-N 0.000 abstract 1
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 208000011775 arteriosclerosis disease Diseases 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 2
- 230000001093 anti-cancer Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 210000004165 myocardium Anatomy 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 208000024827 Alzheimer disease Diseases 0.000 description 1
- 206010008132 Cerebral thrombosis Diseases 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010061216 Infarction Diseases 0.000 description 1
- 201000001429 Intracranial Thrombosis Diseases 0.000 description 1
- 102000007330 LDL Lipoproteins Human genes 0.000 description 1
- 108010007622 LDL Lipoproteins Proteins 0.000 description 1
- 201000004681 Psoriasis Diseases 0.000 description 1
- 208000034189 Sclerosis Diseases 0.000 description 1
- 206010039966 Senile dementia Diseases 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 210000005013 brain tissue Anatomy 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000007574 infarction Effects 0.000 description 1
- 235000013622 meat product Nutrition 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 235000020660 omega-3 fatty acid Nutrition 0.000 description 1
- 230000019240 optic nerve development Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000004382 potting Methods 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 230000010349 pulsation Effects 0.000 description 1
- 206010039073 rheumatoid arthritis Diseases 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
- A23P10/35—Encapsulation of particles, e.g. foodstuff additives with oils, lipids, monoglycerides or diglycerides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Seal oil soft capsules containing coenzyme Q10 mainly comprise the following effective components: seal oil (containing eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), docosapentaenoic acid (DPA) and squalene), coenzyme Q10, and vitamin E. The main auxiliary materials of the seal oil soft capsules are water, glycerin and edible animal gelatin. The invention has the following beneficial effects: Omega-3 highly unsaturated fatty acids (EPA, DHA, DPA) and fat-soluble coenzyme Q10 are effectively combined and the above components furthermore cooperate with each other, so as to better prevent and improve cardiovascular and cerebrovascular diseases. Simultaneously, coenzyme Q10 provides more energy to cardiac muscle cells, so as to reinforce the function of heart and effectively improve the symptoms of cardiovascular and cerebrovascular diseases.
Description
(1) technical field
The present invention relates to a kind of soft capsule of fur seal, especially a kind of soft capsule of fur seal that contains Co-Q10, belongs to health food technology field.
(2) background technology
At present, along with improving constantly of living standard, people constantly increase the intake of higher fatty acid meat product, incident is the continuous rising of fat content in blood, and the diseases such as the arterial sclerosis causing thus, thrombus, coronary heart disease, affect and have endangered middle-aged and old Health and Living quality day by day.In order to prevent the generation of this type of disease, people start more edible seal oil series products, due to existing various seal oil series products ubiquities on market: active ingredient is simple, functional component content is low, functional component proportioning is unreasonable, cause that product function is single, the shortcoming of DeGrain, be difficult to play desirable prophylactic effect.
(3) summary of the invention
The present invention is in order to make up the deficiencies in the prior art, a kind of soft capsule of fur seal that contains Co-Q10 is provided, main active ingredient is: seal oil [contain EPA(eicosapentaenoic acid), DHA(DHA), DPA(clupanodonic acid), squalene], Co-Q10, vitamin E, major auxiliary burden is water, glycerine and edible animal gelatin.
EPA in seal oil: be commonly called as " blood vessel street cleaner ", there is the vascular sclerosis of preventing, cardiovascular and cerebrovascular embolism, reduce hypertension, high fat of blood and cholesterol, suppress the effects such as platelet aggregation.DHA: being commonly called as " docosapentaenoic acid ", is the necessary nutriment of brain tissue and optic nerve development and Function.Can be used for strengthening memory, promote infant's intellectual development and improve IQ, prevention and treatment senile dementia.DPA: the immunity that can promote and improve human body.To diabetes, rheumatoid arthritis, psoriasis, asthma, ulcer colo-enteritis etc. all has therapeutic action.Squalene: natural.Contribute to anti-cancer and anticancer and skin care to make it smooth and full of elasticity.
Co-Q10 is that prevention of arterial sclerosis forms the most effective anti-oxidant composition, can resist the oxidation effect of low-density lipoprotein in blood, reduce artery sclerosis and form, and be also prevention miocardial infarction and most important one defence line of cerebral thrombosis.Co-Q10 can not only be produced energy for cardiac muscle, also can stablize cardiac pulses and heart conducting system, lowers the risk of suffering from rhythm abnormality or palpitaition problem.Once cardiac muscle can be produced more multipotency, just can bring into play more powerful pulsation ability.Blood more circulates, and blood vessel has more flexible elasticity, makes the heart naturally also can be more healthy.
Vitamin E can protect highly unsaturated fatty acid (EPA, DHA, DPA) not oxidized, extends shelf life of products.
The invention has the beneficial effects as follows, this soft capsule of fur seal effectively combines ω-3 highly unsaturated fatty acid (EPA, DHA, DPA) and fat-soluble Co-Q10, between composition, further acts synergistically, and can better improve and prevent cardiovascular and cerebrovascular disease.Co-Q10, for cardiac muscle cell provides more multipotency, strengthens cardiac function simultaneously, can rapidly, effectively improve cardiovascular and cerebrovascular disease symptom.
(4) specific embodiment
1, preparation content: raw material seal oil, Co-Q10, vitamin E is admixed together according to certain formula, stir, the mass percent of content functional component net content is: EPA:10~15%, DHA:20~25%, DPA:10 ~ 15%, Co-Q10: 5~10%, squalene 4 ~ 8%, the vitamin E that all the other compositions are 1% and other the non-functional component in seal oil.
2, make capsule body material: take edible gelatin, glycerine and pure water as utricule raw material, glycerine and pure water are proportionally injected in glue pot, and heating is stirred to 75 ℃ of left and right, then adds gelatin, continue to stir final vacuum deaeration in 20~30 minutes, make and obtain envelop materials.
3, the content preparing and capsule body are passed through to pelleting, moulding, wash ball, are dried, make finished product soft capsule of fur seal.
Claims (2)
1. a soft capsule of fur seal that contains Co-Q10, is characterized in that: the mass percent of capsule 's content raw material be seal oil [contain EPA(eicosapentaenoic acid), DHA(DHA), DPA(clupanodonic acid), squalene]: 90~95%, Co-Q10: 5~10%, vitamin E: 1%.
2. a kind of soft capsule of fur seal that contains Co-Q10 according to claim 1, it is characterized in that: capsule 's content functional component mass percent is EPA:10~15%, DHA:20~25%, DPA:10 ~ 15%, Co-Q10: 5~10%, squalene 4 ~ 8% the vitamin E that all the other compositions are 1% and other the non-functional component in seal oil.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410297589.6A CN104172151A (en) | 2014-06-29 | 2014-06-29 | Seal oil soft capsules containing coenzyme Q10 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410297589.6A CN104172151A (en) | 2014-06-29 | 2014-06-29 | Seal oil soft capsules containing coenzyme Q10 |
Publications (1)
Publication Number | Publication Date |
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CN104172151A true CN104172151A (en) | 2014-12-03 |
Family
ID=51953717
Family Applications (1)
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CN201410297589.6A Pending CN104172151A (en) | 2014-06-29 | 2014-06-29 | Seal oil soft capsules containing coenzyme Q10 |
Country Status (1)
Country | Link |
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CN (1) | CN104172151A (en) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002188096A (en) * | 2000-10-12 | 2002-07-05 | Kanegafuchi Chem Ind Co Ltd | New glyceride, method for producing the same and its use |
CN1518989A (en) * | 2003-01-21 | 2004-08-11 | 刘 威 | Soft capsule of fur seal and application in preparing health products for regulating blood fat |
CN102551041A (en) * | 2010-12-08 | 2012-07-11 | 浙江金诺康生物制药有限公司 | Refined seal oil, seal oil soft capsules and application of seal oil soft capsules in preparing health products for improving chemical liver injury |
CN102726736A (en) * | 2011-04-01 | 2012-10-17 | 陕西省功能食品生产力促进中心有限公司 | Health food capable of resisting oxidation and reducing blood fat and preparation method thereof |
CN103006636A (en) * | 2012-11-23 | 2013-04-03 | 西安泰科迈医药科技有限公司 | Medicinal composition for reinforcing immunity and resisting oxidation and capsule preparation method thereof |
-
2014
- 2014-06-29 CN CN201410297589.6A patent/CN104172151A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002188096A (en) * | 2000-10-12 | 2002-07-05 | Kanegafuchi Chem Ind Co Ltd | New glyceride, method for producing the same and its use |
CN1518989A (en) * | 2003-01-21 | 2004-08-11 | 刘 威 | Soft capsule of fur seal and application in preparing health products for regulating blood fat |
CN102551041A (en) * | 2010-12-08 | 2012-07-11 | 浙江金诺康生物制药有限公司 | Refined seal oil, seal oil soft capsules and application of seal oil soft capsules in preparing health products for improving chemical liver injury |
CN102726736A (en) * | 2011-04-01 | 2012-10-17 | 陕西省功能食品生产力促进中心有限公司 | Health food capable of resisting oxidation and reducing blood fat and preparation method thereof |
CN103006636A (en) * | 2012-11-23 | 2013-04-03 | 西安泰科迈医药科技有限公司 | Medicinal composition for reinforcing immunity and resisting oxidation and capsule preparation method thereof |
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Application publication date: 20141203 |