CN104161617A - Novel condom and preparation method thereof - Google Patents

Novel condom and preparation method thereof Download PDF

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Publication number
CN104161617A
CN104161617A CN201410438404.9A CN201410438404A CN104161617A CN 104161617 A CN104161617 A CN 104161617A CN 201410438404 A CN201410438404 A CN 201410438404A CN 104161617 A CN104161617 A CN 104161617A
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China
Prior art keywords
condom
wax
nitroglycerin
layer
head end
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Pending
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CN201410438404.9A
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Chinese (zh)
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蔺新力
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Individual
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Individual
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Priority to CN201410438404.9A priority Critical patent/CN104161617A/en
Publication of CN104161617A publication Critical patent/CN104161617A/en
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Abstract

The invention relates to a novel condom and a preparation method of the novel condom. The condom is provided with a low-melting-point wax ball or wax layer, and active materials are contained inside the wax ball or wax layer. In the preparation process, the wax ball or wax layer is arranged at the head end of the inner surface of the elastic condom, furthermore, the condom is provided with a wax layer, and the condom can also contain a lubricant layer. The active materials comprise spermatocides like nonoxynol-9, vasodilator such as nicotinic acid, sildena majorfil and nitroglycerin, and male sensitivity reduction agents like benzocaine. The novel condom not only has the common functions of contraception and prevention of venereal disease inflection, but also can prevent and treat erection problems, including impotence, premature ejaculation, failure of hardness or insufficient hardness and the like.

Description

A kind of condom and preparation method thereof
Technical field
The present invention relates to a kind of condom that includes vasodilation or other activating agents.There is treatment male sexual disorder and increase the effects such as Male sexual ability.The present invention is except normal contraception and prevent spread of sexually transmitted diseases, can also prevent and treat erection problem, comprises sexual impotence, and premature ejaculation cannot be strong or strong deficiency etc.
Background technology
Erection problem is the more common problem that a male faces.The cause of this problem can be physiology aspect, may be also psychological aspects to a greater extent.But because reasons such as social customs, patient has a bone in the throat mostly, and does not think pathologic problems, so also do not seek regular medical treatment, do not help.However, this problem has serious impact to patient, causes great menticide, and hinders under many circumstances normal Process of Insemination, thereby must produce offspring with spermatozoa insemination method if needed.The 'Xiduofeng ' class medicines such as viagra can solve the problem of some patients were, but inapplicable to these class oral drugs of a lot of patients.A kind of more blanket, the method for local application will help a lot of this class patients.But the method for this class penis or glans penis local application is easy to import into the other side when sexual intercourse, cause the discomfort of the other side's health.The form that for example this class vasodilator of nitroglycerin is prepared into unguentum can be applied on penis and glans penis, helps to keep penis strong.But verified this type of medicine can be absorbed by vagina in sexual intercourse process, and the malaise symptoms such as cause that the other side has a headache.In this case, with a kind of, can, in contraception and preventive disease transmission, prevent that the non-purpose of local application from propagating and diffusion as the physical barriers of condom class.
Summary of the invention
The basic function of condom is that a kind of physical barriers is provided when sexual intercourse, to prevent body fluid, and the mutual exchange of seminal fluid and other materials.The object of this invention is to provide a kind of condom, in conventional condom inside, add effective ingredient.This effective ingredient can play treatment erection problem when application, remains strong, prevents premature ejaculation, improves life quality, reduces side effect, and strengthens the effects such as contraceptive effect.
The technical solution used in the present invention is: a kind of condom, comprise condom inner surface, and at the head end of condom inner surface, be provided with active agent layer, in described active agent layer, contain active component.
Above-mentioned condom, is provided with wax layer outward in active agent layer, and in described wax layer, containing native paraffin and molecular weight is that 400-1500 or fusing point are the Polyethylene Glycol of 25-40 ℃.
Above-mentioned condom, is provided with lubricant layer; In described lubricant layer, contain glycerol and propylene glycol.
In certain embodiments, the present invention makes wax pearl or wax layer by active component, and in the preparation wax pearl or wax is placed on to the head end of condom inner surface, obtains active agent layer.This active agent layer can prevent that when storage and transport condom active component runs off or the outside of " pollution " condom, the danger of effective ingredient horizontal transmission while having avoided using.In condom application process, due to the effects such as hotness lubricant of body temperature and condom inside, wax layer dissolves, and makes active component in glans penis and fully effect and/or the absorption of penis part, reaches the therapeutic effect of expection.
In certain embodiments, active component can comprise spermicide as N-9, to strengthen contraceptive effect, and still can play contraceptive efficacy in the situation that Contraceptive barrier destroys.
In certain embodiments, active component can comprise " erection agent " or vasodilation as nitroglycerin, nicotinic acid, 'Xiduofeng ' (sildenafil) class medicine or L-arginine.This active component can stimulate and maintain erection, thereby and the hardness of strengthening erection penis prevent in sexual intercourse process that condom comes off and cause contraceptive failure and strengthen both sides' sexual intercourse pleasant sensation.
In certain embodiments, active component can comprise male's desensitization agent as benzocaine (benzocaine) etc.Benzocaine can reduce the sensitivity of penis when sexual intercourse, thereby prevents premature ejaculation.
In certain embodiments, the nitroglycerin in active component can be adsorbed on lactose fine grained or powder, is then prepared into a kind of compositions that comprises lanoline and vaseline oil.In this dosage form, nitroglycerin is the effective ingredient that stimulates and keep erection, and lactose powder absorption nitroglycerin prevents its volatilization, and lanoline and vaseline oil are the reinforcing agents that nitroglycerin active component skin absorbs.
Nitroglycerin is to treat the anginal long-range history that has, and effectiveness is remarkable, the medicine that price is cheap.This effectiveness derives from its vasodilative function.According to same principle, nitroglycerin by epithelium by penis local absorption after, can promote and keep the expansion of penis vessel, thereby cause and to maintain penis strong.So the combination dosage forms of nitroglycerin and lanoline and vaseline can effectively be treated erection problem disease.
Nitroglycerin itself is a kind of explosibility thing.In the present invention, in dosage form, first-selection is adsorbed in nitroglycerin on a kind of stabilizing agent.After this kind of stabilizing agent absorption nitroglycerin, be prepared to imperceptible granule, this micron particles can infiltrate easily and in skin, reach local drug effect.First-selected stabilizing agent is lactose.The percentage by weight that nitroglycerin can be prepared into 4-25% is adsorbed on lactose, the percentage by weight as 10%.
Lanoline is applied to lubricant or emollient cream conventionally, and the skin that can strengthen nitroglycerin at this absorbs.Lanoline, for a long time for cosmetics, has proved safe and reliable.In this invention, apply pharmaceutical grade lanoline.
In certain embodiments, can be by active fraction preparation in low melt wax pearl or wax layer.Wax pearl or wax layer can comprise take Polyethylene Glycol as basic wax, and in this wax, the molecular weight of Polyethylene Glycol is selected between 25 ℃-40 ℃ according to fusing point.One of illustration alternative is application nature Cera Flava solidified liquid.The fusing point of this type of Cera Flava can add the Polyethylene Glycol of suitable molecular weight to reduce in liquid condition.The described wax pearl containing activating agent or the head end that wax layer can be prepared in condom inner surface.
In further embodiments, the invention provides the method for coating hotness lubricant in the interior surface layers of condom.Hotness lubricant can comprise glycerol and anhydrous or containing the polypropylene glycol of a small amount of water.When thering is a small amount of moisture content that the condom of anhydrous hotness lubricant and skin of penis produce and contact, due to glycerol and polypropylene glycol exothermic dissolution, lubricant heats up, and can help low melt wax pearl or wax layer to dissolve and discharge effective ingredient, make skin pore expand simultaneously, contribute to the absorption of effective ingredient.
In further embodiments, the invention provides a kind of method of preparing condom.The method comprises the following step: the low melt wax liquid that contains active component that a kind of molten state is provided; A condom is provided; The wax drop of certain volume is entered to the head end of condom inner surface, form wax pearl; The wax pearl allowing at the inner head end of condom is in cold curing, and forming active agent layer is wax pearl form; Or the wax drop of certain volume is entered to the head end of condom inner surface, form wax layer; Allow wax layer at the inner head end of condom in cold curing, forming active agent layer is wax layer form, to prepared condom package.The preparation method of molten state wax liquid is for mixing to form uniform liquid solution by low melt wax liquid with the activating agent of low melting point more.Alternative or additional scheme is for to add low melt wax liquid by the activating agent of water-soluble fine powdered.
Further in certain embodiments, the invention provides the method that another kind is prepared condom.The method comprises the following step: a condom is provided; Active component in certain liq or pulverulence is applied to or is fixed on to the head end of condom inside, form active agent layer; The low melt wax drop of the molten state of certain volume is entered on the active agent layer of condom inner surface head end, form wax layer; Allow wax layer at the inner head end of condom in cold curing; To prepared condom package.
Further in certain embodiments, the invention provides the method that another kind is prepared condom.The method comprises further provides hotness lubricant to the described condom that contains low melt wax pearl or wax layer and activating agent.Concrete grammar comprises the following step: the low melt wax liquid that contains activating agent that a kind of molten state is provided; A condom is provided; The wax drop of certain volume is entered to the head end of condom inner surface; Allow wax liquid at the inner head end of condom in cold curing; Hotness lubricant is smeared or sprayed in condom inside; To prepared condom package.
Further in certain embodiments, the present invention also provides another kind to prepare the method for condom.Concrete grammar comprises the following step: a condom is provided; To at the active component of certain liq or pulverulence, put into the head end of condom inside, form active agent layer; The low melt wax drop of the molten state of certain volume is entered on the active agent layer of condom inner surface head end, allow wax liquid at the inner head end of condom in cold curing, form coating of wax layer; On wax layer, smear or spray into hotness lubricant, form lubricant layer, to prepared condom package.
Described " low melting point " refers to a kind of material, and as wax or other suitable carriers, this carrier is softening or fusing under the body temperature of approximately 37 ℃.In one embodiment, described low melt wax pearl or wax layer be softening or fusing under body temperature, discharges active substance simultaneously.In another embodiment, described wax or other suitable carriers approximately 25 ℃ to 40 ℃ between fusing.
Term used " erection agent " and " vasodilation " refer to a class active substance, this class material can make vasodilation, is increased to the blood circulation of organ, increases nitric oxide level, produce heat or cause the sense of breaking out of a kind of hotness or libido, and can slow down or therapeutic is reacted obstacle.This type of material should be easier absorbs not and other composition generation side reactions by skin.Other compositions refer to that carrier mass used in the present invention is as wax, Polyethylene Glycol, and glycerol, polypropylene glycol, and other prepare the composition of condom.
Described wax pearl or wax layer can comprise synthetic or natural wax.Native paraffin generally can comprise montan wax, Brazil wax, Cera Flava, candelilla, wax palm palmitic acid etc.Synthetic wax generally comprises the polyethylene of Polyethylene Glycol or polyethylene and modification, the polypropylene of polypropylene and modification etc.If the fusing point of wax used is higher than the scope of 25 ℃ to 40 ℃, can be by this wax fusing, then add the wax of low melting point of fusing as the Polyethylene Glycol of suitable molecular weight, after mixing, solidify to reach fusing point at 25 ℃ of low melt waxes to 40 ℃ of scopes again.
Described wax pearl or wax layer can comprise Polyethylene Glycol (PEG).A kind of illustrative PEG is the PEG600 with 20-25 ℃ of fusing point.Another kind of possible PEG is the PEG1500 with 44-48 ℃ of fusing point.This wax can mix with other low melt waxes to form wax pearl or the wax layer of suitable fusing point.So in one or more embodiment, described wax pearl or wax layer have total molecular weight (or 600 to 1300, or 800-1100) in approximately 400 to 1500 scope, have fusing point between 25 ℃ to 40 ℃ (even 36 ℃ to 39 ℃) simultaneously.Another PEG that is suitable for applying in the low melt wax of this patent is that fusing point is the PEG1000 of 38 ℃.Take Polyethylene Glycol as a basic wax, and it contains PEG-6 and PEG-32 that molecular weight is 470-530g/mol, also can apply in the present invention.In some compositions containing PEG-wax and active component of the present invention, when the dampness producing with skin contacts, can in contact site, improve Yue Wenduda 5-7 ℃ because of fusing heating.This kind of intensification effect can skin expansion pore, enhanced activity composition osmotic absorption.
In one or more embodiment, nitroglycerin used in a condom (10% is adsorbed in lactose powder) is about 50-150 milligram, first-selected 100 milligrams.Wax pearl or wax layer can reach 1 gram or more.
In description herein, term used " condom " refers to that condom includes active material and comprises that spermicide is as N-9, vasodilation is as nicotinic acid, 'Xiduofeng ' (sildenafil) and nitroglycerin, and male's desensitization agent is as benzocaine (benzocaine) etc.These activating agents can mix with low melt wax pearl or wax layer, or are protected by low melt wax pearl or wax layer, are prepared into condom.Described condom also can contain hotness lubricant layer.
In description herein, term used " activating agent ", " active substance ", " active material ", " effectively agent ", " active substance ", and " effectively material " be general, it includes but not limited to: spermicide is as N-9, and vasodilation is as nicotinic acid, 'Xiduofeng ' (sildenafil) and nitroglycerin, and male's desensitization agent is as benzocaine (benzocaine) etc.
Although the present invention describes in different embodiment, the description of these different embodiment need to be interpreted as to be illustration of the present invention, and the explanation to principle of the present invention and application, rather than invention is limited in described embodiment.Those skilled in the art of the invention be it is evident that and can under the prerequisite that does not depart from aim of the present invention and scope, to method of the present invention, carry out various modifications and changes.Therefore, the present invention includes modifications and changes and the equivalents thereof within the scope of accessory claim.
Accompanying drawing explanation
Fig. 1 is the first version of condom of the present invention.
Fig. 2 is the second version of condom of the present invention.
Fig. 3 is the third version of condom of the present invention.
Fig. 4 is the 4th kind of version of condom of the present invention.
The specific embodiment
The following example furnishes an example but does not limit the present invention.Claim of the present invention is embodied by claims.Following example is usingd nitroglycerin as main active in addition.Other active component, comprise that spermicide is as N-9, vasodilation is as nicotinic acid (niacin usp), 'Xiduofeng ' (sildenafil) class medicine and L-arginine, and male's desensitization agent as benzocaine (benzocaine) etc. all can be part or all of replacement example in nitroglycerin, to form the different illustrations of difference in functionality.
Embodiment 1:
A kind of condom for the treatment of male sexual disorder.Described condom preparation method is: the PEG-600 of the native paraffin of approximately 400 milligrams and approximately 600 milligrams is mixed, heat to obtain wax liquid (during heating, temperature is higher than fusing point 1-10 ℃); Nitroglycerin-the lactose powder of approximately 200 milligrams (by weight percentage 10% nitroglycerin being made with 90% lactose powder mixing) is mixed homogeneously with the wax liquid of fusing, obtain blended wax liquid; Blended wax drop is entered to the head end of condom (1) inner surface, blended wax liquid at room temperature solidifies, and forms the active agent layer (2) of wax pearl form, to prepared condom package.Its structure as shown in Figure 1.
Embodiment 2:
A kind of condom for the treatment of male sexual disorder.Described condom preparation method is: the PEG-800 of the native paraffin of approximately 200 milligrams and approximately 400 milligrams is mixed, heat to obtain wax liquid; Nitroglycerin-the lactose powder of 100 milligrams (by weight percentage 10% nitroglycerin being made with 90% lactose powder mixing) and the lanoline (pharmaceutical grade) of 100 milligrams are mixed homogeneously with the wax liquid of fusing, obtain blended wax liquid; Blended wax drop is entered to the head end of condom (1) inner surface, blended wax liquid at room temperature solidifies, and forms the active agent layer (2) of wax layer form, to prepared condom package.Its structure as shown in Figure 2.
Embodiment 3:
A kind of condom for the treatment of male sexual disorder.Described condom preparation method is: the PEG-1000 of the native paraffin of approximately 100 milligrams and approximately 500 milligrams is mixed, heat to obtain wax liquid; Nitroglycerin-the lactose powder of 100 milligrams (by weight percentage 10% nitroglycerin is mixed and made with lactose powder) and the glycerol of 100 milligrams are mixed homogeneously with the wax liquid of fusing, obtain blended wax liquid; Blended wax drop is entered to the head end of condom inner surface, blended wax liquid at room temperature solidifies, and forms active agent layer, to prepared condom package.
Embodiment 4:
A kind of condom for the treatment of male sexual disorder.Described condom preparation method is: the PEG-600 of the native paraffin of approximately 300 milligrams and 300 milligrams is mixed, heat to obtain wax liquid; Nitroglycerin-the lactose powder of 100 milligrams (by weight percentage 10% nitroglycerin is mixed and made with lactose powder), the lanoline (pharmaceutical grade) of 100 milligrams and the glycerol of 100 milligrams are mixed homogeneously with the wax liquid of fusing, obtain blended wax liquid; Blended wax drop is entered to the head end of condom inner surface, blended wax liquid at room temperature solidifies, and forms active agent layer, to prepared condom package.
Embodiment 5:
A kind of condom for the treatment of male sexual disorder.Described condom preparation method is: the PEG-600 of the native paraffin of approximately 500 milligrams and approximately 300 milligrams is mixed, heat to obtain wax liquid; Nitroglycerin-the lactose powder of 200 milligrams (by weight percentage 10% nitroglycerin is mixed and made with lactose powder) is mixed homogeneously with the wax liquid of fusing, obtain blended wax liquid; Blended wax drop is entered to the head end of condom inner surface, blended wax liquid at room temperature solidifies, and forms active agent layer; By the mixed with propylene glycol of the glycerol of anhydrous 100 milligrams and 100 milligrams and spread upon the surface of active agent layer, form lubricant layer; To prepared condom package.
Embodiment 6:
A kind of condom for the treatment of male sexual disorder.Described condom preparation method is: the PEG-800 of the native paraffin of approximately 400 milligrams and approximately 400 milligrams is mixed, heat to obtain wax liquid; Nitroglycerin-the lactose powder of 100 milligrams (by weight percentage 10% nitroglycerin is mixed and made with lactose powder) is mixed homogeneously with the wax liquid of fusing, obtain blended wax liquid; Blended wax drop is entered to the head end of condom inner surface, blended wax liquid at room temperature solidifies, and forms active agent layer; By the mixed with propylene glycol of the glycerol of anhydrous 100 milligrams and 100 milligrams and spread upon the surface of active agent layer, form lubricant layer; To prepared condom package.
Embodiment 7:
A kind of condom for the treatment of male sexual disorder.Described condom preparation method is: the dehydrated alcohol mixed dissolution by the nitroglycerin-lactose powder of approximately 200 milligrams (by weight percentage 10% nitroglycerin is mixed and made with 90% lactose powder) with 200 milligrams, then mixed liquor is splashed into the head end of condom (1) inner surface, after ethanol evaporation, on the head end of condom inner surface, form the film that contains nitroglycerin, be active agent layer (2); The PEG-600 of the native paraffin of approximately 300 milligrams and 300 milligrams is mixed, heat to obtain wax liquid; Wax drop is entered to the head end of condom inner surface and covers in active agent layer, and wax liquid at room temperature solidifies, and forms wax layer (3); To prepared condom package.Its structure as shown in Figure 3.
Embodiment 8:
A kind of condom for the treatment of male sexual disorder.Described condom preparation method is: the dehydrated alcohol mixed dissolution by the nitroglycerin-lactose powder of 200 milligrams (by weight percentage 10% nitroglycerin is mixed and made with lactose powder) with 200 milligrams, then mixed liquor is splashed into the head end of condom (1) inner surface, after ethanol evaporation, on the head end of condom inner surface, form the film that contains nitroglycerin, be active agent layer (2); The PEG600 of the native paraffin of approximately 300 milligrams and approximately 300 milligrams is mixed, heat to obtain wax liquid, wax drop is entered to the head end of condom inner surface and covers in active agent layer, wax liquid at room temperature solidifies, and forms wax layer (3); By the mixed with propylene glycol of the glycerol of anhydrous 100 milligrams and 100 milligrams and spread upon on wax layer, form lubricating layer (4); To prepared condom package.Its structure as shown in Figure 4.
Embodiment 9:
A kind of condom for the treatment of male sexual disorder.Described condom preparation method is: the dehydrated alcohol mixed dissolution by the nitroglycerin-lactose powder of 200 milligrams (by weight percentage 10% nitroglycerin is mixed and made with lactose powder) with 200 milligrams, then mixed liquor is splashed into the head end of condom inner surface, after ethanol evaporation, on the head end of condom inner surface, forming the film that contains nitroglycerin, is active agent layer; The PEG800 of the native paraffin of approximately 200 milligrams and approximately 400 milligrams is mixed, heat to obtain wax liquid, wax drop is entered to the head end of condom inner surface and covers in active agent layer, wax liquid at room temperature solidifies, and forms wax layer; The Herba Menthae alcohol radical of the glycerol of anhydrous 100 milligrams, the propylene glycol of 100 milligrams and 10 milligrams is strengthened to mix lubricant and spread upon the surface of wax layer, form lubricant layer; To prepared condom package.
Embodiment 10:
A kind of condom for the treatment of male sexual disorder.Described condom preparation method is: the dehydrated alcohol mixed dissolution by the nitroglycerin-lactose powder of 200 milligrams (by weight percentage 10% nitroglycerin is mixed and made with lactose powder) with 200 milligrams, then mixed liquor is splashed into the head end of condom inner surface, after ethanol evaporation, on the head end of condom inner surface, forming the film that contains nitroglycerin, is active agent layer; The PEG800 of the native paraffin of approximately 200 milligrams and approximately 400 milligrams is mixed, heat to obtain wax liquid, wax drop is entered to the head end of condom inner surface and covers in active agent layer, wax liquid at room temperature solidifies, and forms wax layer; The surface of the Aloe gel of the glycerol of anhydrous 100 milligrams, the propylene glycol of 100 milligrams and 10 milligrams being mixed and spreads upon to wax layer, forms lubricant layer; To prepared condom package.

Claims (10)

1. a condom, comprises condom inner surface, it is characterized in that: the head end at condom inner surface is provided with active agent layer, in described active agent layer, contains active component.
2. condom as claimed in claim 1, is characterized in that: in active agent layer, be provided with wax layer outward, in described wax layer, containing native paraffin and molecular weight is that 400-1500 or fusing point are the Polyethylene Glycol of 25-40 ℃.
3. condom as claimed in claim 1 or 2, is characterized in that: be provided with lubricant layer; Described lubricant layer comprises glycerol and propylene glycol.
4. condom as claimed in claim 1, is characterized in that: described active component is vasodilation, spermicide and/or male's desensitization agent.
5. condom as claimed in claim 4, is characterized in that: described vasodilation is nitroglycerin, nicotinic acid, 'Xiduofeng ' class medicine or L-arginine; Described spermicide is N-9; Described male's desensitization agent is benzocaine.
6. condom as claimed in claim 5, is characterized in that: described active component is nitroglycerin.
7. condom as claimed in claim 6, is characterized in that: by weight percentage the nitroglycerin of 4-25% is adsorbed on the stabilizing agent of solid state powder or fine particulate, described stabilizing agent comprises lactose.
8. a preparation method for condom, is characterized in that method is as follows: by native paraffin and molecular weight, be that 400-1500 or fusing point are that the Polyethylene Glycol heat fused of 25-40 ℃ obtains wax liquid; Nitroglycerin-lactose powder is mixed homogeneously with wax liquid, obtain blended wax liquid; Blended wax drop is entered to the head end of condom inner surface, blended wax liquid solidifies under room temperature, in the head end formation active agent layer of condom inner surface; To prepared condom package; Described nitroglycerin-lactose powder is to contain by weight percentage the nitroglycerin of 4-25%.
9. a preparation method for condom, is characterized in that method is as follows: by native paraffin and molecular weight, be that 400-1500 or fusing point are that the Polyethylene Glycol heat fused of 25-40 ℃ obtains wax liquid; Nitroglycerin-lactose powder is mixed homogeneously with wax liquid, obtain blended wax liquid; Blended wax drop is entered to the head end of condom inner surface; Blended wax liquid solidifies under room temperature, in the head end formation active agent layer of condom inner surface; By glycerol and mixed with propylene glycol and spread upon outside active agent layer, form lubricant; To prepared condom package; Described nitroglycerin-lactose powder is to contain by weight percentage the nitroglycerin of 4-25%.
10. the preparation method of a condom, it is characterized in that method is as follows: by nitroglycerin-lactose powder and dehydrated alcohol mixed dissolution, obtain mixed liquor, mixed liquor is splashed into the head end of condom inner surface, evaporation dehydrated alcohol makes nitroglycerin-lactose powder form the membranaceous head end that invests condom inner surface, forms active agent layer; By native paraffin and molecular weight, be that 400-1500 or fusing point are the Polyethylene Glycol heat fused of 25-40 ℃, obtain wax liquid, wax drop is entered to the head end of condom inner surface and covers active agent layer, wax liquid at room temperature solidifies, and obtains wax layer; By glycerol, propylene glycol and Aloe gel mix homogeneously, and spread upon the surface of wax layer, obtain lubricant layer; To prepared condom package; Described nitroglycerin-lactose powder is to contain by weight percentage the nitroglycerin of 4-25%.
CN201410438404.9A 2014-08-29 2014-08-29 Novel condom and preparation method thereof Pending CN104161617A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022155962A1 (en) * 2021-01-25 2022-07-28 优印(上海)信息科技有限公司 New cbd condom

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4829991A (en) * 1987-01-06 1989-05-16 Medical Engineering Corp. Method and device for stimulating an erection
CN1292691A (en) * 1998-01-30 2001-04-25 富图拉医药有限公司 Preparation for treatment of erectile dysfunction
CN1498096A (en) * 2001-03-30 2004-05-19 ��ͼ��ҽҩ��չ���޹�˾ Condom with erectogenic composition
WO2010014863A1 (en) * 2008-07-31 2010-02-04 Ansell Healthcare Products Llc Condom with coating having capsules
CN101868200A (en) * 2007-10-26 2010-10-20 安塞尔保健产品有限责任公司 Condom with multi-functional coatings
CN102083395A (en) * 2008-04-29 2011-06-01 安塞尔保健产品有限责任公司 Condom with localized active agent

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4829991A (en) * 1987-01-06 1989-05-16 Medical Engineering Corp. Method and device for stimulating an erection
CN1292691A (en) * 1998-01-30 2001-04-25 富图拉医药有限公司 Preparation for treatment of erectile dysfunction
CN1498096A (en) * 2001-03-30 2004-05-19 ��ͼ��ҽҩ��չ���޹�˾ Condom with erectogenic composition
CN101868200A (en) * 2007-10-26 2010-10-20 安塞尔保健产品有限责任公司 Condom with multi-functional coatings
CN102083395A (en) * 2008-04-29 2011-06-01 安塞尔保健产品有限责任公司 Condom with localized active agent
WO2010014863A1 (en) * 2008-07-31 2010-02-04 Ansell Healthcare Products Llc Condom with coating having capsules

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022155962A1 (en) * 2021-01-25 2022-07-28 优印(上海)信息科技有限公司 New cbd condom

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Application publication date: 20141126