CN104147019B - 闭花木酮的o-(四氢吡咯基)乙基衍生物在制备预防或治疗胰腺纤维化药物中的应用 - Google Patents
闭花木酮的o-(四氢吡咯基)乙基衍生物在制备预防或治疗胰腺纤维化药物中的应用 Download PDFInfo
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- CN104147019B CN104147019B CN201410375246.7A CN201410375246A CN104147019B CN 104147019 B CN104147019 B CN 104147019B CN 201410375246 A CN201410375246 A CN 201410375246A CN 104147019 B CN104147019 B CN 104147019B
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- cleistanone
- ethyl derivative
- nafoxidine base
- pancreatic gland
- pharmaceutically acceptable
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- 229950002366 nafoxidine Drugs 0.000 title claims abstract description 37
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 title claims abstract description 36
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- PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical compound O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 claims description 5
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- JEYWNNAZDLFBFF-UHFFFAOYSA-N Nafoxidine Chemical compound C1CC2=CC(OC)=CC=C2C(C=2C=CC(OCCN3CCCC3)=CC=2)=C1C1=CC=CC=C1 JEYWNNAZDLFBFF-UHFFFAOYSA-N 0.000 abstract 3
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- IAZDPXIOMUYVGZ-WFGJKAKNSA-N Dimethyl sulfoxide Chemical compound [2H]C([2H])([2H])S(=O)C([2H])([2H])[2H] IAZDPXIOMUYVGZ-WFGJKAKNSA-N 0.000 description 8
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CN104758298A (zh) * | 2015-04-15 | 2015-07-08 | 南京大学 | 闭花木酮的o-(1h-四氮唑基)乙基衍生物在制备治疗或预防肾纤维化药物中的应用 |
CN104739846A (zh) * | 2015-04-15 | 2015-07-01 | 南京大学 | 闭花木酮的o-(1h-四氮唑基)乙基衍生物在制备预防或治疗胰腺纤维化药物中的应用 |
CN104825466A (zh) * | 2015-04-29 | 2015-08-12 | 南京广康协生物医药技术有限公司 | 闭花木酮的o-(苯并咪唑基)乙基衍生物在制备预防或治疗胰腺纤维化药物中的应用 |
CN104800213A (zh) * | 2015-05-12 | 2015-07-29 | 南京大学 | Daphmalenine A衍生物在制备预防或治疗胰腺纤维化药物中的应用 |
CN104922122A (zh) * | 2015-05-27 | 2015-09-23 | 南京广康协生物医药技术有限公司 | Daphmalenine A的O-(二乙胺基)乙基衍生物在制备预防或治疗胰腺纤维化药物中的应用 |
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CN102000086A (zh) * | 2006-03-06 | 2011-04-06 | 上海医药工业研究院 | 积雪酸在制备预防或治疗胰腺纤维化的药物中的应用 |
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