CN104143283A - Gram-negative bacterium peptidoglycan structural model teaching tool - Google Patents

Gram-negative bacterium peptidoglycan structural model teaching tool Download PDF

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Publication number
CN104143283A
CN104143283A CN201410372693.7A CN201410372693A CN104143283A CN 104143283 A CN104143283 A CN 104143283A CN 201410372693 A CN201410372693 A CN 201410372693A CN 104143283 A CN104143283 A CN 104143283A
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CN
China
Prior art keywords
spheroid
gram
pearl shape
balls
shape string
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Pending
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CN201410372693.7A
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Chinese (zh)
Inventor
邓超
齐丹
蔡宇婷
沈丹
王阳阳
徐晓宇
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Jiangnan University
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Jiangnan University
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Publication date
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Priority to CN201410372693.7A priority Critical patent/CN104143283A/en
Publication of CN104143283A publication Critical patent/CN104143283A/en
Pending legal-status Critical Current

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Abstract

The invention relates to a gram-negative bacterium peptidoglycan structural model teaching tool. The gram-negative bacterium peptidoglycan structural model teaching tool comprises balls representing different amino sugars, and connecting rods representing glucosidic bonds. The balls comprise the first balls and the second balls. The first balls and the second balls are arranged in a vertical column at intervals. The first balls are connected with the second balls through the connecting rods. Bead strings are arranged below the second balls. Each bead string comprises four beads, wherein the third bead is connected with the fourth bead of the bead string below the second ball in the adjacent column. The model teaching tool is of a three-dimensional structure. The teaching tool is simple in structure and convenient to dismount. The structure of the gram-negative bacterium peptidoglycan can be reflected more visually, and students can understand and memorize the knowledge well.

Description

A kind of gram-negative bacteria peptide glycan structural model teaching aid
Technical field
The present invention relates to a kind of model teaching aid, relate in particular to a kind of Grain-negative bacterium peptide glycan structural model teaching aid.
Background technology
Gram-negative bacteria cell wall is thinner, about 10-15nm, and in cell membrane, peptide glycan content is few, only has 1-2 layer, and every layer thickness is 1nm, accounts for 10% of dry cell weight.Gram-negative bacteria peptide glycan You Ν ?acetylglucosamine, Ν ?the macromolecule complex that is polymerized of the subunit that forms of acetylmuramic acid and a few amino acids short peptide chain, peptidoglycan monomer You Ν ?acetylglucosamine, Ν ?acetylmuramic acid, tetrapeptide side chain form.In order to allow student strengthen understanding and the memory to gram-negative bacteria peptide glycan structure and to distinguish this structure and the difference of gram positive bacteria cell membrane, rely on merely floor map or teaching courseware to satisfy the demand.
Summary of the invention
The object of the invention is cannot know the structure of showing gram-negative bacteria peptide glycan in order to overcome floor map, be convenient to student simultaneously and understand and remember, a kind of dismountable gram-negative bacteria peptide glycan structural model teaching aid is provided.
The present invention adopts following technical scheme: a kind of gram-negative bacteria peptide glycan structural model teaching aid, comprise the spheroid that represents different amino sugars, and represent the connecting link of glycosidic bond, described spheroid comprises the first spheroid and the second spheroid, it is perpendicular row that described the first spheroid and the second spheroid are spaced, the first spheroid is connected by connecting link with the second spheroid, and described the second spheroid below is provided with pearl shape string.One side level connection joint of the 3rd ball in described pearl shape string has the 4th ball of the pearl shape string of the second spheroid below in adjacent row; Described the first spheroid, the second spheroid, connecting link and pearl shape string form 3-D solid structure.
Further, described the first spheroid and the second spheroid left and right sides are provided with round jack.
Further, described pearl shape string comprises four balls.
Further, the downside of described the second spheroid has jack.
Further, on four balls in described pearl shape string, be respectively equipped with the through hole running through, four balls in described pearl shape string connect by hub rod, and described hub rod upper end is connected in the jack of the second spheroid downside.
Further, the 3rd ball one side in described pearl shape string has hole clipping, and the 4th ball side in adjacent pearl shape string has hub rod, and the 4th ball of described pearl shape string is connected in by hub rod in the hole clipping of the 3rd ball of adjacent pearl shape string.
In superincumbent technical scheme, the first spheroid represent Ν ?acetylglucosamine, the second spheroid represent Ν ?acetylmuramic acid, connecting link representative connect Ν ?acetylglucosamine He Ν ?β-1.4 glycosidic bond of acetylmuramic acid, pearl shape string represents tetrapeptide side chain, wherein the first ball represents that L – alanine, the second ball represent that D – glutamic acid, the 3rd ball represent that diaminopimelic acid, the 4th ball represent D – alanine.
Gram-negative bacteria peptide glycan structural model teaching aid structure provided by the invention is simple, for convenience detach, can clearer displaying gram-negative bacteria peptide glycan structure.
Brief description of the drawings
Fig. 1 is structural representation of the present invention.
Fig. 2 is the schematic diagram of disassembling of the present invention
Reference numeral: the hub rod 5-1 of the first spheroid 1, the second spheroid 2, connecting link 3, pearl shape string 4, the first spheroid and the second round jack 1-1 in the spheroid left and right sides, the second spheroid downside jack 2-1, the hub rod 3-1 that is connected four balls, the 3rd ball one side hole clipping 4-1, the 4th ball one side.
Embodiment
Below in conjunction with accompanying drawing, the invention will be further described.
As Fig. 1, shown in Fig. 2, a kind of gram-negative bacteria peptide glycan structural model teaching aid, comprise the spheroid that represents different amino sugars, and represent the connecting link of glycosidic bond, wherein, the first spheroid 1 is red, the second spheroid 2 is yellow, the first spheroid 1 and the second spheroid 2 are spaced, the first spheroid and the second spheroid left and right sides are provided with round jack 1-1, centre connects by black plastic connecting link 3, the downside of described the second spheroid 2 has jack 2-1, the second spheroid 2 belows are provided with pearl shape string 4, pearl shape string 4 comprises four spheroids, four spheroid middle parts have through hole, four spheroids connect by hub rod 3-1, the upper end of hub rod is connected in the jack of the second spheroid, in described pearl shape string 4, a side of the 3rd ball has hole clipping 4-1, the 4th ball side in adjacent pearl shape string 4 has hub rod 5-1, the 4th ball of described pearl shape string 4 is connected in by hub rod 5-1 in the hole clipping of the 3rd ball of adjacent pearl shape string 4, described the first spheroid 1, the second spheroid 2, connecting link 3 and pearl shape string 4 have formed 3-D solid structure.
The first spheroid represent Ν ?acetylglucosamine, the second spheroid represent Ν ?acetylmuramic acid, connecting link representative connect Ν ?acetylglucosamine He Ν ?β-1.4 glycosidic bond of acetylmuramic acid, pearl shape string represents tetrapeptide side chain, and four spheroids represent L – alanine, D – glutamic acid, diaminopimelic acid and D – alanine successively from top to bottom.

Claims (7)

1. a gram-negative bacteria peptide glycan structural model teaching aid, it is characterized in that: comprise the spheroid that represents different amino sugars, and represent the connecting link of glycosidic bond, described spheroid comprises the first spheroid (1) and the second spheroid (2), described the first spheroid (1) and the second spheroid (2) are spaced, the first spheroid (1) is connected by connecting link (3) with the second spheroid (2), described the second spheroid (2) below is provided with pearl shape string (4), the 3rd ball in described pearl shape string (4) is connected with the 4th ball of the pearl shape string of the second spheroid (2) below in adjacent row, described the first spheroid (1), the second spheroid (2), connecting link (3) and pearl shape string (4) form 3-D solid structure.
2. a kind of gram-negative bacteria peptide glycan structural model teaching aid as claimed in claim 1, is characterized in that: described the first spheroid and the second spheroid left and right sides are provided with round jack (1-1).
3. a kind of gram-negative bacteria peptide glycan structural model teaching aid as claimed in claim 1, is characterized in that: described pearl shape string (4) comprises four balls.
4. a kind of gram-negative bacteria peptide glycan structural model teaching aid as claimed in claim 1, is characterized in that: the downside of described the second spheroid (2) has jack (2-1).
5. a kind of gram-negative bacteria peptide glycan structural model teaching aid as claimed in claim 1, it is characterized in that: on four balls in described pearl shape string (4), be respectively equipped with the through hole running through, four balls of described pearl shape string (4) connect by hub rod (3-1), and described hub rod upper end is connected in the jack of the second spheroid (2) downside.
6. a kind of gram-negative bacteria peptide glycan structural model teaching aid as claimed in claim 1, it is characterized in that: the 3rd ball one side in described pearl shape string (4) has hole clipping (4-1), the 4th ball side in adjacent pearl shape string (4) has hub rod (5-1), and the 4th ball of described pearl shape string (4) is connected in by hub rod (5-1) in the hole clipping of the 3rd ball of adjacent pearl shape string (4).
7. a kind of gram-negative bacteria peptide glycan structural model teaching aid as claimed in claim 1, it is characterized in that: described the first spheroid (1) represent Ν ?acetylglucosamine, the second spheroid (2) represent Ν ?acetylmuramic acid, connecting link (3) representative connect Ν ?acetylglucosamine He Ν ?β-1.4 glycosidic bond of acetylmuramic acid, pearl shape string (4) represents tetrapeptide side chain, and four spheroids represent L – alanine, D – glutamic acid, diaminopimelic acid and D – alanine successively from top to bottom.
CN201410372693.7A 2014-07-31 2014-07-31 Gram-negative bacterium peptidoglycan structural model teaching tool Pending CN104143283A (en)

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CN201410372693.7A CN104143283A (en) 2014-07-31 2014-07-31 Gram-negative bacterium peptidoglycan structural model teaching tool

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201196848Y (en) * 2008-03-14 2009-02-18 范瑛琳 DNA double helix demonstration teaching aid
WO2010043046A1 (en) * 2008-10-16 2010-04-22 Mcmaster University Peptide inhibitors of type iii secretion
JP4690630B2 (en) * 2002-05-02 2011-06-01 独立行政法人科学技術振興機構 MD-2 gene modified model non-human animal
CN102831814A (en) * 2012-09-06 2012-12-19 苏州大学 Model teaching aid of endotoxin of cell walls of gram-negative bacteria
US8440423B2 (en) * 2007-02-05 2013-05-14 U.S. Department Of Energy Bioremediation of nanomaterials
CN103198744A (en) * 2013-04-28 2013-07-10 苏州大学 Gram positive bacteria cell wall model teaching aid
CN204010479U (en) * 2014-07-31 2014-12-10 江南大学 A kind of gram-negative bacteria peptide glycan structural model teaching aid

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4690630B2 (en) * 2002-05-02 2011-06-01 独立行政法人科学技術振興機構 MD-2 gene modified model non-human animal
US8440423B2 (en) * 2007-02-05 2013-05-14 U.S. Department Of Energy Bioremediation of nanomaterials
CN201196848Y (en) * 2008-03-14 2009-02-18 范瑛琳 DNA double helix demonstration teaching aid
WO2010043046A1 (en) * 2008-10-16 2010-04-22 Mcmaster University Peptide inhibitors of type iii secretion
CN102831814A (en) * 2012-09-06 2012-12-19 苏州大学 Model teaching aid of endotoxin of cell walls of gram-negative bacteria
CN103198744A (en) * 2013-04-28 2013-07-10 苏州大学 Gram positive bacteria cell wall model teaching aid
CN204010479U (en) * 2014-07-31 2014-12-10 江南大学 A kind of gram-negative bacteria peptide glycan structural model teaching aid

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Title
谢国武: "《免疫学基础与病原生物学》", 31 January 2013, article ""免疫学基础与病原生物学"" *

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Application publication date: 20141112