CN104127745A - Use of traditional Chinese medicinal preparation in treatment of scaly hand-foot fungus infection - Google Patents
Use of traditional Chinese medicinal preparation in treatment of scaly hand-foot fungus infection Download PDFInfo
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- CN104127745A CN104127745A CN201410333607.1A CN201410333607A CN104127745A CN 104127745 A CN104127745 A CN 104127745A CN 201410333607 A CN201410333607 A CN 201410333607A CN 104127745 A CN104127745 A CN 104127745A
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Abstract
The invention relates to a use of a traditional Chinese medicinal preparation in treatment of scaly hand-foot fungus infection. The traditional Chinese medicinal preparation is prepared by using the following raw medicines, by weight, 20-30 parts of Geranium wilfordii Maxim., 20-30 parts of coix seed, 5-10 parts of garlic, 30-40 parts of Cortex Magnoliae Officinalis, 30-40 parts of Artemisia argyi, 30-40 parts of loquat leaf, 20-30 parts of Sophora flavescens, 20-30 parts of Saxifraga stolonifera Curt., 10-20 parts of Herba Taraxaci, 10-20 parts of Radix Scutellariae and 10-20 arts of pomegranate rind. The traditional Chinese medicinal preparation has the following advantages: 1, the preparation can clear heat, detoxify, cool blood and invigorate blood circulation, improves the physical and chemical environment of infected positions, and has a substantial scaly hand-foot fungus infection treatment effect; 2, the preparation has a simple preparation method and a low cost; and 3, the preparation is prepared by pure traditional Chinese medicines, is an external preparation, and has no toxic side effects.
Description
Technical field
The present invention relates to the field of Chinese medicines, specifically, is a kind of purposes of Chinese medicine preparation treatment squama type brothers fungal infection.
Background technology
Brothers' fungal infection refers to that dermatophytes infringement refers between toe, toe, the caused infection of palm sole of the foot portion.In swimming pool and bathhouse, wear public slippers easy infection foot fungus, hands is often really rolled up and is infected and ill by foot.Pathogen is mainly trichophyton, alpha fungus and epidermophyton etc., and infection by Candida albicans is quite a few in recent years sees.
Primary disease is divided into four types by clinical manifestation: 1. immersion-type: skin whitening between common toe (finger), and rotten to the corn, dipping, clear-cut margin, removes the epidermis of dipping, leaves moist scarlet newborn skin.2. vesicle: vesicle appears in common vola or palm, and even several vesicles are fused into larger vesicle, clear border, skin is not red, and bleb is broken desquamation.3. squama type: mainly with desquamation, be main, have minority sailor tinea pedis bleb, the dry desquamation of bleb, clear border, inflammation is not obvious.4. incrassation type: common palm sole of the foot pachyderma, hydroa aestivale desquamation, enters winter skin cracking.Primary disease is more common in adult, often summer attack or increase the weight of.
The treatment of brothers' fungal infection be take external used medicine and oral drugs as main, and more is antimycotic chemicals on the market, and antibiotic side effect is larger, easily produces drug resistance, is more difficult to treatment after recurrence.Chinese medicine composition is safer, aspect treatment brothers fungal infection, is possessing larger potentiality.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of squama type brothers fungal infection.
The technical scheme that the present invention takes is: the purposes of a kind of Chinese medicine preparation in the medicine of preparation treatment squama type brothers fungal infection, described Chinese medicine preparation is made by the crude drug of following weight portion: Herba Erodii 20-30 part, Semen Coicis 20-30 part, Bulbus Allii 5-10 part, Cortex Magnoliae Officinalis 30-40 part, Folium Artemisiae Argyi 30-40 part, Folium Eriobotryae 30-40 part, Radix Sophorae Flavescentis 20-30 part, Herba Saxifragae 20-30 part, Herba Taraxaci 10-20 part, Radix Scutellariae 10-20 part, Pericarpium Granati 10-20 part.
Described Chinese medicine preparation is made by the crude drug of following weight portion: Herba Erodii 22-28 part, Semen Coicis 22-28 part, Bulbus Allii 6-9 part, Cortex Magnoliae Officinalis 33-37 part, Folium Artemisiae Argyi 33-37 part, Folium Eriobotryae 33-37 part, Radix Sophorae Flavescentis 22-28 part, Herba Saxifragae 22-28 part, Herba Taraxaci 12-18 part, Radix Scutellariae 12-18 part, Pericarpium Granati 12-18 part.
Described Chinese medicine preparation is made by the crude drug of following weight portion: 25 parts of Herba Erodiis, 25 parts of Semen Coicis, 8 parts, Bulbus Allii, 35 parts of Cortex Magnoliae Officinalis, 35 parts of Folium Artemisiae Argyis, 35 parts of Folium Eriobotryaes, 25 parts of Radix Sophorae Flavescentiss, 25 parts of Herba Saxifragaes, 15 parts of Herba Taraxacis, 15 parts of Radix Scutellariaes, 15 parts of Pericarpium Granatis.
Beneficial effect of the present invention is: 1, the invention provides a kind of Chinese medicine preparation, this Chinese medicine preparation possesses heat-clearing and toxic substances removing, and removing heat from blood and promoting blood circulation improves the effects such as affected part physicochemical environment, and opponent's Foot fungus infection has significant therapeutic effect.2, preparation method is simple, and cost is low.3, by pure Chinese medicine, made, and be external, have no side effect.
The specific embodiment
Below in conjunction with embodiment, the present invention is further illustrated.
embodiment 1
get by weight 25 parts of Herba Erodiis, 25 parts of Semen Coicis, 8 parts, Bulbus Allii, 35 parts of Cortex Magnoliae Officinalis, 35 parts of Folium Artemisiae Argyis, 35 parts of Folium Eriobotryaes, 25 parts of Radix Sophorae Flavescentiss, 25 parts of Herba Saxifragaes, 15 parts of Herba Taraxacis, 15 parts of Radix Scutellariaes, 15 parts of Pericarpium Granatis, pulverize, cross 80 mesh sieves, fine powder, in fine powder, add the water of 8 times of volumes to decoct, during interval Jia Shui, decoct altogether 6 hours, making last decoction liquor volume is 8 times that primary fine powder body amasss, and filtering residue, obtains preparation.
embodiment 2
Get by weight 30 parts of Herba Erodiis, 20 parts of Semen Coicis, 10 parts, Bulbus Allii, 30 parts of Cortex Magnoliae Officinalis, 40 parts of Folium Artemisiae Argyis, 30 parts of Folium Eriobotryaes, 30 parts of Radix Sophorae Flavescentiss, 20 parts of Herba Saxifragaes, 20 parts of Herba Taraxacis, 10 parts of Radix Scutellariaes, 20 parts of Pericarpium Granatis, pulverize, cross 80 mesh sieves, fine powder, in fine powder, add the water of 7 times of volumes to decoct, during interval Jia Shui, decoct altogether 6 hours, making last decoction liquor volume is 7 times that primary fine powder body amasss, and filtering residue, obtains preparation.
embodiment 3
Get by weight 20 parts of Herba Erodiis, 30 parts of Semen Coicis, 5 parts, Bulbus Allii, 40 parts of Cortex Magnoliae Officinalis, 30 parts of Folium Artemisiae Argyis, 40 parts of Folium Eriobotryaes, 20 parts of Radix Sophorae Flavescentiss, 30 parts of Herba Saxifragaes, 10 parts of Herba Taraxacis, 20 parts of Radix Scutellariaes, 10 parts of Pericarpium Granatis, pulverize, cross 80 mesh sieves, fine powder, in fine powder, add the water of 10 times of volumes to decoct, during interval Jia Shui, decoct altogether 6 hours, making last decoction liquor volume is 10 times that primary fine powder body amasss, and filtering residue, obtains preparation.
embodiment 4
Get by weight 28 parts of Herba Erodiis, 22 parts of Semen Coicis, 9 parts, Bulbus Allii, 33 parts of Cortex Magnoliae Officinalis, 37 parts of Folium Artemisiae Argyis, 33 parts of Folium Eriobotryaes, 28 parts of Radix Sophorae Flavescentiss, 22 parts of Herba Saxifragaes, 18 parts of Herba Taraxacis, 12 parts of Radix Scutellariaes, 18 parts of Pericarpium Granatis, pulverize, cross 80 mesh sieves, fine powder, in fine powder, add the water of 5 times of volumes to decoct, during interval Jia Shui, decoct altogether 6 hours, making last decoction liquor volume is 5 times that primary fine powder body amasss, and filtering residue, obtains preparation.
embodiment 5
Get by weight 22 parts of Herba Erodiis, 28 parts of Semen Coicis, 6 parts, Bulbus Allii, 37 parts of Cortex Magnoliae Officinalis, 33 parts of Folium Artemisiae Argyis, 37 parts of Folium Eriobotryaes, 22 parts of Radix Sophorae Flavescentiss, 28 parts of Herba Saxifragaes, 12 parts of Herba Taraxacis, 18 parts of Radix Scutellariaes, 12 parts of Pericarpium Granatis, pulverize, cross 80 mesh sieves, fine powder, in fine powder, add the water of 5 times of volumes to decoct, during interval Jia Shui, decoct altogether 6 hours, making last decoction liquor volume is 5 times that primary fine powder body amasss, and filtering residue, obtains preparation.
embodiment 6
Get by weight 25 parts of Herba Erodiis, 25 parts of Semen Coicis, 8 parts, Bulbus Allii, 35 parts of Cortex Magnoliae Officinalis, 35 parts of Folium Artemisiae Argyis, 37 parts of Folium Eriobotryaes, 22 parts of Radix Sophorae Flavescentiss, 28 parts of Herba Saxifragaes, 12 parts of Herba Taraxacis, 18 parts of Radix Scutellariaes, 12 parts of Pericarpium Granatis, pulverize, cross 80 mesh sieves, fine powder, in fine powder, add the water of 6 times of volumes to decoct, during interval Jia Shui, decoct altogether 6 hours, making last decoction liquor volume is 6 times that primary fine powder body amasss, and filtering residue, obtains preparation.
embodiment 7
1, physical data
Select age bracket 60 of the squama type brothers fungal infection patients of 18 years old to 69 years old, course of disease 1.5-12, symptom is: take desquamation as main, has minority sailor tinea pedis bleb, the dry desquamation of bleb, clear border, inflammation is not obvious.Be divided at random treatment group and matched group, each 30 examples.The data there was no significant differences such as two groups of sexes, age, have comparability.
2, test method
2.1 Therapeutic Method
Treatment group is used the preparation of embodiment 1 preparation to soak ill brothers 30 minutes every day, after slightly wipe away dry.10 days course for the treatment of.Treat 4 courses for the treatment of.
The preparation that matched group is prepared in order to lower Chinese crude drug soaks ill brothers: 25 parts of Herba Erodiis, 25 parts of Pericarpium Citri Reticulataes, 8 parts, Bulbus Allii, 35 parts of Cortex Magnoliae Officinalis, 35 parts of Folium Artemisiae Argyis, 35 parts of Folium Eriobotryaes, 25 parts of Radix Sophorae Flavescentiss, 25 parts of Herba Saxifragaes, 15 parts of Herba Taraxacis, 15 parts of Radix Scutellariaes, formulation preparation method is with embodiment 1.The same treatment group of Therapeutic Method.
2.2 observation item
Before and after treatment, squama decortication, sailor's tinea pedis bleb situation are observed, and observed epidermis fungal culture situation.
3, criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, forms without squama, and without tinea bleb, epidermis fungal culture is negative, has no recurrence in half a year.Take a turn for the better: clinical symptoms significantly alleviates, and squama and tinea bleb obviously reduce, and epidermis fungal culture is positive.Invalid: clinical symptoms is without being clearly better or increasing the weight of, and epidermis fungal culture is positive.
4, therapeutic outcome
The results are shown in Table 1.Result shows, Chinese medicine preparation opponent Foot fungus infection of the present invention has definite curative effect, and effect is better than the Chinese medicine preparation (P<0.05) of matched group, shows that its compatibility is precise and appropriate, and curative effect is very significant.
Table 1 liang group curative effect comparison
| ? | Number of cases | Effective | Effectively | Invalid | Total effective rate |
| Test group | 30 | 21 | 8 | 1 | 96.67% |
| Matched group | 30 | 11 | 12 | 5 | 76.67% |
Claims (3)
1. the Chinese medicine preparation purposes in the medicine of preparation treatment squama type brothers fungal infection, it is characterized in that, described Chinese medicine preparation is made by the crude drug of following weight portion: Herba Erodii 20-30 part, Semen Coicis 20-30 part, Bulbus Allii 5-10 part, Cortex Magnoliae Officinalis 30-40 part, Folium Artemisiae Argyi 30-40 part, Folium Eriobotryae 30-40 part, Radix Sophorae Flavescentis 20-30 part, Herba Saxifragae 20-30 part, Herba Taraxaci 10-20 part, Radix Scutellariae 10-20 part, Pericarpium Granati 10-20 part.
2. purposes according to claim 1, it is characterized in that, described Chinese medicine preparation is made by the crude drug of following weight portion: Herba Erodii 22-28 part, Semen Coicis 22-28 part, Bulbus Allii 6-9 part, Cortex Magnoliae Officinalis 33-37 part, Folium Artemisiae Argyi 33-37 part, Folium Eriobotryae 33-37 part, Radix Sophorae Flavescentis 22-28 part, Herba Saxifragae 22-28 part, Herba Taraxaci 12-18 part, Radix Scutellariae 12-18 part, Pericarpium Granati 12-18 part.
3. purposes according to claim 2, it is characterized in that, described Chinese medicine preparation is made by the crude drug of following weight portion: 25 parts of Herba Erodiis, 25 parts of Semen Coicis, 8 parts, Bulbus Allii, 35 parts of Cortex Magnoliae Officinalis, 35 parts of Folium Artemisiae Argyis, 35 parts of Folium Eriobotryaes, 25 parts of Radix Sophorae Flavescentiss, 25 parts of Herba Saxifragaes, 15 parts of Herba Taraxacis, 15 parts of Radix Scutellariaes, 15 parts of Pericarpium Granatis.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410333607.1A CN104127745A (en) | 2014-07-15 | 2014-07-15 | Use of traditional Chinese medicinal preparation in treatment of scaly hand-foot fungus infection |
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| CN201410333607.1A CN104127745A (en) | 2014-07-15 | 2014-07-15 | Use of traditional Chinese medicinal preparation in treatment of scaly hand-foot fungus infection |
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- 2014-07-15 CN CN201410333607.1A patent/CN104127745A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 蔡德海 等: "中草药抗真菌研究十年回顾", 《河北医学》 * |
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