CN104123752A - Human organ three dimensional (3D) modeling method capable of performing 3D printing - Google Patents
Human organ three dimensional (3D) modeling method capable of performing 3D printing Download PDFInfo
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Abstract
Disclosed is a human organ three dimensional (3D) modeling method capable of performing 3D printing. The human organ 3D modeling method capable of performing the 3D printing includes: obtaining a tissue and organ medical image; simultaneously generating axial two dimensional (2D) images, sagittal 2D images and coronal 2D images of three same organs in the axial direction, the sagittal direction and the coronal direction of the tissue and organ medical image; respectively and correspondingly performing axial surface image separation, sagittal axial surface image separation and coronal axial surface image separation on the above images; performing 3D fusion of the 2D images against an image separation result; judging whether the 3D fusion takes effect or not; extracting surface features of a 3D image in medical image processing software, adding an individual file which is generated into a model, and saving the individual file as an STL formatted file; performing smoothing and polishing processing on the surface of the model; generating a file which can be printed in 3D mode and performing the 3D printing; judging whether a model which is printed out is real or not. The model which is printed out by using the human organ 3D modeling method capable of performing the 3D printing is not only realistic in surface feature, but also has an internal structure completely consistent with the structure of a human body.
Description
Technical field
The present invention relates to a kind of three-dimensional modeling method.Particularly relate to a kind of three-dimensional modeling method that can carry out the human organ of 3D printing.
Background technology
The domestic 3D modeling of human organ the technology of printable one-tenth mock-up that not yet has this moulding.Substantially stop at three-dimensional reconstruction, and reconstruction technique also only limits to the reconstruction of profile, its inner structure cannot be surveyed, as the number of patent application human limb three-dimensional model building based on image outline that is 200410089299.9, it is to adopt revolving conic surface to set up human limb three-dimensional model, by the sets of line segments of articulation point and tie point, become the skeleton structure of casing play representative limbs, skin layer represents with revolving conic surface, and each limbs only need be adjusted two deformation parameters just can reflect the distortion of people's limb skin.It is a kind of modeling of the people's of only limiting to limbs profile.
Medical imaging technology by 2D to 3D even 4D develop, 3D/4D fetal ultrasound scanning is quite general, but 3D medical science modeling technique is also in the budding stage.Ye Youdui human tissue organ carries out three-dimensional imaging at present, but is only to rest on the software simulation stage.
Summary of the invention
Technical matters to be solved by this invention is that a kind of three-dimensional modeling method that can carry out the human organ of 3D printing that 3D human medical image is converted into mock-up is provided.
The technical solution adopted in the present invention is: a kind of three-dimensional modeling method that can carry out the human organ of 3D printing, comprises the steps:
1) obtain histoorgan medical image;
2) histoorgan medical image is generated in axial, sagittal and crown three directions simultaneously to axial X-Y scheme, sagittal X-Y scheme and the crown two dimensional image of three homologs;
3) to step 2) result carry out accordingly respectively axial vane surface separation of images, sagittal axial vane surface separation of images and crown axial vane surface separation of images;
4) to step 3) the separation of images result that the obtains three-dimensional of carrying out two dimensional image merges;
5) whether judgement fusion comes into force, and is to enter next step, otherwise turns back to step 3);
6) in Medical Image Processing software, 3-D view is carried out to 3-D view Surface characterization, generate independent file and join in model, and save as STL formatted file;
7) model surface is carried out to smoothing processing and polishing processing;
8) be generated as file that can 3 D-printing and carry out 3 D-printing;
9) whether the model that prints of judgement is true, is model generation, otherwise turns back to step 3).
Step 1) described histoorgan medical image is to adopt the mode of nuclear magnetic resonance or ultrasonic scanning obtain the image file of DICOM form and store.
Step 2) utilize Medical Image Processing software Simpleware or Amira or Mimics to complete.
Step 3) described separation of images is to carry out in Medical Image Processing software Simpleware or Amira or Mimics.
Step 4) described fusion is by step 3) three groups of image separate files obtaining import in computer aided design software Solidworks simultaneously and carry out manual amendment fusion, obtain model.
Step 5) whether described fusion comes into force, and refers to that the model of fusion reflects real organ contours.
Step 7) described carries out smoothing processing and polishing processing to model surface, is in STL formatted file importing Auto CAD software, to carry out level and smooth and polishing.
Step 8) described 3 D-printing is to select precision from the three-dimensional printer of 30 microns~300 microns.
A kind of three-dimensional modeling method that can carry out the human organ of 3D printing of the present invention, to utilize medical science perspective imaging technology, human organ is carried out to two dimension successively to be scanned or 3-D scanning, again view data is integrated, not only surface characteristics is true to nature to adopt the model that method of the present invention prints, and its inner structure is also in full accord with organization of human body.It is different that its precision is looked the three-dimensional printer of employing, uses to take its precision of desktop level printer that the reproducible PLA rigid plastic of environmental protection is main printed material and can reach 100 microns.
Accompanying drawing explanation
Fig. 1 is a kind of figure of three-dimensional modeling method of the human organ that can carry out 3D printing.
Embodiment
Below in conjunction with embodiment and accompanying drawing, a kind of three-dimensional modeling method that can carry out the human organ of 3D printing of the present invention is described in detail.
As shown in Figure 1, a kind of three-dimensional modeling method that can carry out the human organ of 3D printing of the present invention, comprises the steps:
1) obtain histoorgan medical image,
Described histoorgan medical image is to adopt the mode of nuclear magnetic resonance or ultrasonic scanning obtain the image file of DICOM form and store; Wherein,
Nuclear magnetic resonance:
The Siemens 3T scanister of take is example, and Whole Body or single organ are carried out respectively to crown, sagittal, axial scan, and every layer of precision is 1.1 * 1.1mm, bed thickness 3mm, before layer and layer continuously every, obtain respectively the human organ image of three groups of different scanning modes, image is stored with DICOM form.The method does not have specific (special) requirements to nuclear magnetic resonance apparatus, as long as can obtain picture rich in detail in three directions.
Ultrasonic scanning:
The four-dimensional color ultrasound instrument of the Madison Multimedia Dynamic of take is example, and this instrument can carry out dynamic scan to human organ and fetus.After scanning completes, the mvl formatted file that scanning is generated imports Madison picture browsing software (3DXI PC Viewer) image is derived, and is stored as equally DICOM form, conveniently carries out next step image processing.
2) histoorgan medical image is utilized Medical Image Processing software Simpleware or Amira or Mimics in axial, sagittal and crown three directions, generate axial X-Y scheme, sagittal X-Y scheme and the crown two dimensional image of three homologs simultaneously;
3) to step 2) result carry out accordingly respectively axial vane surface separation of images, sagittal axial vane surface separation of images and crown axial vane surface separation of images, described separation of images is to carry out in Medical Image Processing software Simpleware or Amira or Mimics;
Specifically the image file of DICOM form is imported to the extraction of carrying out zone-by-zone analysis and organ edge in professional medical science image processing software Simpleware, this step is extremely important, and the quality of its last organ edge extracting directly has influence on the success or failure that three-dimensional organ of later stage is integrated.
4) to step 3) the separation of images result that the obtains three-dimensional of carrying out two dimensional image merges,
Described fusion is by step 3) three groups of image separate files obtaining import in computer aided design software Solidworks simultaneously and carry out manual amendment fusion, obtain model;
Specifically in axial, sagittal, crown three directions, generate the edge extracting figure (stl file form) of three homologs simultaneously, three groups of files are imported in computer aided design software (as Solidworks) simultaneously and merged, to guarantee that model can reflect real organ contours.
5) whether judgement fusion comes into force, and is to enter next step, otherwise turns back to step 3);
Whether described fusion comes into force, and refers to that the model of fusion reflects real organ contours, as differed too many with true organ.
6) in Medical Image Processing software, 3-D view is carried out to 3-D view Surface characterization, generate independent file and join in model, and save as STL formatted file;
7) model surface is carried out to smoothing processing and polishing processing,
Described carries out smoothing processing and polishing processing to model surface, is in STL formatted file importing Auto CAD software, to carry out level and smooth and polishing;
If model merges successfully, the now separation of organ completes substantially with structure, but some surface characteristics of organ still need to strengthen, and at this moment need to return in Medical Image Processing software image is carried out to detail extraction, such as the facial characteristics of fetus, generate independent file and join among model.Final mask saves as stl file form, imports and in Auto CAD software, carries out level and smooth and polish.
8) be generated as can 3 D-printing file: different depending on used three-dimensional printer, also different by the 3 D-printing file that stl file is converted.For example use MakerBot the 5th generation desktop printer, the 3 D-printing file layout of generation is .makerbot, and precision is 100 microns~300 microns;
9) whether the model that prints of judgement is true, is model generation, otherwise turns back to step 3).
The model printing should be three-dimensional lively, and smooth surface, can truly reflect the apperance of human organ, if do not meet this condition, should not return to step 3) again process.
Printer model needs propping material sometimes, and while removing propping material, care should be used to is careful, take and does not affect the outward appearance of model as main prerequisite.
Adopt a kind of three-dimensional modeling method that can carry out the human organ of 3D printing of the present invention to combine with 3D printer, simulated data is converted into 3D model, the fetus whole body generating or facial partial model can be used as neonate father and mother and leave another selection own and that household commemorates for, again because its data are all picked up from human body, the medical model generating is thus also more true to nature, and the improvement of medical lecture model is also had very great help.
Claims (8)
1. can carry out a three-dimensional modeling method for the human organ of 3D printing, it is characterized in that, comprise the steps:
1) obtain histoorgan medical image;
2) histoorgan medical image is generated in axial, sagittal and crown three directions simultaneously to axial X-Y scheme, sagittal X-Y scheme and the crown two dimensional image of three homologs;
3) to step 2) result carry out accordingly respectively axial vane surface separation of images, sagittal axial vane surface separation of images and crown axial vane surface separation of images;
4) to step 3) the separation of images result that the obtains three-dimensional of carrying out two dimensional image merges;
5) whether judgement fusion comes into force, and is to enter next step, otherwise turns back to step 3);
6) in Medical Image Processing software, 3-D view is carried out to 3-D view Surface characterization, generate independent file and join in model, and save as STL formatted file;
7) model surface is carried out to smoothing processing and polishing processing;
8) be generated as file that can 3 D-printing and carry out 3 D-printing;
9) whether the model that prints of judgement is true, is model generation, otherwise turns back to step 3).
2. a kind of three-dimensional modeling method that can carry out the human organ of 3D printing according to claim 1, it is characterized in that step 1) described histoorgan medical image is to adopt the mode of nuclear magnetic resonance or ultrasonic scanning to obtain image file the storage of DICOM form.
3. a kind of three-dimensional modeling method that can carry out the human organ of 3D printing according to claim 1, is characterized in that step 2) utilize Medical Image Processing software Simpleware or Amira or Mimics to complete.
4. a kind of three-dimensional modeling method that can carry out the human organ of 3D printing according to claim 1, is characterized in that step 3) described separation of images is to carry out in Medical Image Processing software Simpleware or Amira or Mimics.
5. a kind of three-dimensional modeling method that can carry out the human organ of 3D printing according to claim 1, it is characterized in that, step 4) described fusion is by step 3) three groups of image separate files obtaining import in computer aided design software Solidworks simultaneously and carry out manual amendment fusion, obtain model.
6. a kind of three-dimensional modeling method that can carry out the human organ of 3D printing according to claim 1, is characterized in that step 5) whether described fusion come into force, and refers to that the model of fusion reflects real organ contours.
7. a kind of three-dimensional modeling method that can carry out the human organ of 3D printing according to claim 1, it is characterized in that, step 7) described carries out smoothing processing and polishing processing to model surface, is in STL formatted file importing Auto CAD software, to carry out level and smooth and polishing.
8. a kind of three-dimensional modeling method that can carry out the human organ of 3D printing according to claim 1, is characterized in that step 8) described 3 D-printing is to select precision from the three-dimensional printer of 30 microns~300 microns.
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