CN104116982B - 含有甲砜霉素的药物组合物 - Google Patents
含有甲砜霉素的药物组合物 Download PDFInfo
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- CN104116982B CN104116982B CN201410377863.0A CN201410377863A CN104116982B CN 104116982 B CN104116982 B CN 104116982B CN 201410377863 A CN201410377863 A CN 201410377863A CN 104116982 B CN104116982 B CN 104116982B
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- parts
- radix
- cough
- herba
- thiamphenicol
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- OTVAEFIXJLOWRX-NXEZZACHSA-N Thiamphenicol Chemical compound CS(=O)(=O)C1=CC=C([C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl)C=C1 OTVAEFIXJLOWRX-NXEZZACHSA-N 0.000 title claims abstract description 28
- 229960003053 Thiamphenicol Drugs 0.000 title claims abstract description 28
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 12
- 206010011224 Cough Diseases 0.000 claims abstract description 59
- 239000003814 drug Substances 0.000 claims abstract description 37
- 239000000203 mixture Substances 0.000 claims abstract description 18
- 229940079593 drugs Drugs 0.000 claims abstract description 13
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 8
- 241000628997 Flos Species 0.000 claims abstract description 7
- 239000002994 raw material Substances 0.000 claims description 4
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- 206010061245 Internal injury Diseases 0.000 description 4
- RAHZWNYVWXNFOC-UHFFFAOYSA-N sulphur dioxide Chemical compound O=S=O RAHZWNYVWXNFOC-UHFFFAOYSA-N 0.000 description 4
- 201000010874 syndrome Diseases 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- WIIZWVCIJKGZOK-RKDXNWHRSA-N Chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 description 3
- 229940097572 Chloromycetin Drugs 0.000 description 3
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
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- 238000002360 preparation method Methods 0.000 description 3
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- 210000000582 Semen Anatomy 0.000 description 2
- 210000000952 Spleen Anatomy 0.000 description 2
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- 230000000844 anti-bacterial Effects 0.000 description 2
- 230000003115 biocidal Effects 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 238000003304 gavage Methods 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- 235000012239 silicon dioxide Nutrition 0.000 description 2
- 239000002893 slag Substances 0.000 description 2
- 102000019632 Acyl transferases Human genes 0.000 description 1
- 108091022082 Acyl transferases Proteins 0.000 description 1
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 241000606124 Bacteroides fragilis Species 0.000 description 1
- 206010061695 Biliary tract infection Diseases 0.000 description 1
- DBAKFASWICGISY-BTJKTKAUSA-N Chlorpheniramine maleate Chemical compound OC(=O)\C=C/C(O)=O.C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 DBAKFASWICGISY-BTJKTKAUSA-N 0.000 description 1
- 229960003782 Dextromethorphan Hydrobromide Drugs 0.000 description 1
- STTADZBLEUMJRG-IKNOHUQMSA-N Dextromethorphan hydrobromide monohydrate Chemical compound O.Br.C([C@@H]12)CCC[C@]11CCN(C)[C@H]2CC2=CC=C(OC)C=C21 STTADZBLEUMJRG-IKNOHUQMSA-N 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 229940023064 Escherichia coli Drugs 0.000 description 1
- 241000192125 Firmicutes Species 0.000 description 1
- 239000009636 Huang Qi Substances 0.000 description 1
- 208000006572 Human Influenza Diseases 0.000 description 1
- 208000008454 Hyperhidrosis Diseases 0.000 description 1
- 206010022000 Influenza Diseases 0.000 description 1
- 229940045505 Klebsiella pneumoniae Drugs 0.000 description 1
- 241000588747 Klebsiella pneumoniae Species 0.000 description 1
- 229940052778 Neisseria meningitidis Drugs 0.000 description 1
- 241000588650 Neisseria meningitidis Species 0.000 description 1
- 208000007944 Nodular Nonsuppurative Panniculitis Diseases 0.000 description 1
- 206010033546 Pallor Diseases 0.000 description 1
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- 235000004348 Perilla frutescens Nutrition 0.000 description 1
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- 229940055033 Proteus mirabilis Drugs 0.000 description 1
- 241000588770 Proteus mirabilis Species 0.000 description 1
- 235000009827 Prunus armeniaca Nutrition 0.000 description 1
- 240000005204 Prunus armeniaca Species 0.000 description 1
- 229960003908 Pseudoephedrine Drugs 0.000 description 1
- KWGRBVOPPLSCSI-WCBMZHEXSA-N Pseudoephedrine Chemical compound CN[C@@H](C)[C@@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WCBMZHEXSA-N 0.000 description 1
- 229960003447 Pseudoephedrine Hydrochloride Drugs 0.000 description 1
- 206010057190 Respiratory tract infection Diseases 0.000 description 1
- 210000003705 Ribosomes Anatomy 0.000 description 1
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 description 1
- 241000607768 Shigella Species 0.000 description 1
- 206010040550 Shigella infection Diseases 0.000 description 1
- 229940076185 Staphylococcus aureus Drugs 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 229940031000 Streptococcus pneumoniae Drugs 0.000 description 1
- 241000193998 Streptococcus pneumoniae Species 0.000 description 1
- 241000193996 Streptococcus pyogenes Species 0.000 description 1
- 241001312524 Streptococcus viridans Species 0.000 description 1
- 229920001949 Transfer RNA Polymers 0.000 description 1
- 108020004566 Transfer RNA Proteins 0.000 description 1
- 206010046577 Urinary tract infection Diseases 0.000 description 1
- 206010047883 Weber-Christian disease Diseases 0.000 description 1
- 201000005661 acute cystitis Diseases 0.000 description 1
- 230000000240 adjuvant Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 125000000266 alpha-aminoacyl group Chemical group 0.000 description 1
- 230000000845 anti-microbial Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- -1 calls thiomycin Chemical compound 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000005260 corrosion Methods 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 238000003748 differential diagnosis Methods 0.000 description 1
- 201000009910 diseases by infectious agent Diseases 0.000 description 1
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- 238000002651 drug therapy Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000002949 hemolytic Effects 0.000 description 1
- 230000037315 hyperhidrosis Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 239000008876 liujunzi Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 210000000056 organs Anatomy 0.000 description 1
- 244000052769 pathogens Species 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- BALXUFOVQVENIU-KXNXZCPBSA-N pseudoephedrine hydrochloride Chemical compound [H+].[Cl-].CN[C@@H](C)[C@@H](O)C1=CC=CC=C1 BALXUFOVQVENIU-KXNXZCPBSA-N 0.000 description 1
- 230000000306 recurrent Effects 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 230000001502 supplementation Effects 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000002194 synthesizing Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 239000000273 veterinary drug Substances 0.000 description 1
Abstract
Description
Claims (1)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201410377863.0A CN104116982B (zh) | 2014-08-01 | 含有甲砜霉素的药物组合物 |
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CN201410377863.0A CN104116982B (zh) | 2014-08-01 | 含有甲砜霉素的药物组合物 |
Publications (2)
Publication Number | Publication Date |
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CN104116982A CN104116982A (zh) | 2014-10-29 |
CN104116982B true CN104116982B (zh) | 2017-01-04 |
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103394004A (zh) * | 2013-08-03 | 2013-11-20 | 赵彦琦 | 一种治疗咳嗽的中药组合物 |
CN103393944A (zh) * | 2013-08-03 | 2013-11-20 | 赵彦琦 | 治疗咳嗽的中药 |
CN103432491A (zh) * | 2013-08-08 | 2013-12-11 | 海安常大技术转移中心有限公司 | 药物组合物 |
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103394004A (zh) * | 2013-08-03 | 2013-11-20 | 赵彦琦 | 一种治疗咳嗽的中药组合物 |
CN103393944A (zh) * | 2013-08-03 | 2013-11-20 | 赵彦琦 | 治疗咳嗽的中药 |
CN103432491A (zh) * | 2013-08-08 | 2013-12-11 | 海安常大技术转移中心有限公司 | 药物组合物 |
Non-Patent Citations (1)
Title |
---|
不明原因慢性咳嗽中医临床研究近况;叶发期;《辽宁中医药大学学报》;20100930;第12卷(第09期);第206-208页 * |
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PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
CB03 | Change of inventor or designer information |
Inventor after: Jiao Yunjuan Inventor after: Shi Qi Inventor after: Song Ying Inventor after: Zhang Jie Inventor after: Liu Boyu Inventor after: Wu Wenjie Inventor before: Huang Xiangbin Inventor before: Li Zhizheng Inventor before: Zhou Dai Inventor before: Xie Panjin |
|
TA01 | Transfer of patent application right |
Effective date of registration: 20160923 Address after: Xinxiang City, Henan province 453003 Jinsui Road No. 601, Xinxiang Medical University Applicant after: Xinxiang Medical College Address before: The new Chengdu high tech Zone of Sichuan province 611731 City Road No. 22 Applicant before: Sichuan Xingkerong Pharmaceutical Co., Ltd. |
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GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170104 Termination date: 20170801 |