CN104069396A - Traditional Chinese medicine for treating chemoradiotherapy-induced leukopenia - Google Patents
Traditional Chinese medicine for treating chemoradiotherapy-induced leukopenia Download PDFInfo
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- CN104069396A CN104069396A CN201410291887.4A CN201410291887A CN104069396A CN 104069396 A CN104069396 A CN 104069396A CN 201410291887 A CN201410291887 A CN 201410291887A CN 104069396 A CN104069396 A CN 104069396A
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Abstract
The invention discloses a traditional Chinese medicine for treating chemoradiotherapy-induced leukopenia. The medicine is characterized by comprising the following raw medicines in parts by weight: 95-115 parts of epimedium herb, 60-80 parts of malaytea scurfpea fruit, 95-115 parts of wolfberry fruit, 60-80 parts of ginseng, 130-150 parts of astragalus, 60-80 parts of angelica sinensis, 200-220 parts of suberect spatholobus stem, 60-80 parts of liquorice and 74-94 parts of pangolin. Proven by hundreds of clinic applications, the traditional Chinese medicine is safe, convenient and easy in use, free of pain, toxicity or anaphylactic reaction and excellent in curative effect.
Description
Technical field
The invention belongs to Chinese medicine composition, relate to a kind of leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy.
Background technology
Chemotherapy is easy to cause leukopenia.When human body peripheral blood numeration of leukocyte continues lower than 4 × 10
9when/L, be called leukopenia.Its cause of disease has the secondary causes such as chemical, radioactivity, infectivity.This disease shows as: lusterless complexion or sallow, have a dizzy spell, weak, low grade fever night sweat, feel sick, inappetence, immunity of organisms lowly, easily catch a cold and bring out various diseases, has a strong impact on people's quality of life and health level.
Summary of the invention
The present invention is in order to make up the deficiencies in the prior art, the leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy that provide a kind of good effect, instant effect, has no side effect.
The present invention is achieved through the following technical solutions:
Leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy of the present invention, it is characterized in that: the crude drug that comprises following parts by weight: Herba Epimedii 95-115 part, Fructus Psoraleae 60-80 part, Fructus Lycii 95-115 part, Radix Ginseng 60-80 part, Radix Astragali 130-150 part, Radix Angelicae Sinensis 60-80 part, Caulis Spatholobi 200-220 part, Radix Glycyrrhizae 60-80 part, Squama Manis 74-94 part.
Leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy of the present invention, also comprises the crude drug of following parts by weight: Rhizoma Polygonati 116-136 part, Colla Corii Asini 74-94 part, Radix Achyranthis Bidentatae 74-94 part, Placenta Hominis 74-94 part, Fructus Hordei Germinatus 95-115 part, Poria 95-115 part.
Leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy of the present invention, comprises the crude drug of following parts by weight: 105 parts of Herba Epimedii, 70 parts of Fructus Psoraleaes, 105 parts of Fructus Lycii, 70 parts of Radix Ginsengs, 140 parts of the Radixs Astragali, 70 parts of Radix Angelicae Sinensis, 210 parts of Caulis Spatholobis, 70 parts, Radix Glycyrrhizae, 84 parts of Squama Maniss.
Leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy of the present invention, also comprises the crude drug of following parts by weight: 126 parts of Rhizoma Polygonatis, 84 parts, Colla Corii Asini, 84 parts of Radix Achyranthis Bidentataes, 84 parts of Placenta Hominiss, 105 parts, Fructus Hordei Germinatus, 105 parts of Poria.
Radix Ginseng, the Radix Astragali, Rhizoma Polygonati, Colla Corii Asini, Placenta Hominis strongly invigorating primordial QI in formula, invigorating the spleen to benefit the lung, promotes the production of body fluid and nourishes blood, and benefit is defended consolidating superficial resistance, calms the nerves and has deficiency of both the splenic and pulmonary QI for tumor patient more, and hinder in gas Tianjin two, the card of sapping one's vitality, the first righting therefore what is called is got rid of evils; Fructus Psoraleae, Herba Epimedii, Fructus Lycii, Radix Achyranthis Bidentatae warming the kidney to activate YANG, strengthening the tendons and bones, nourishing kidney lung moistening, tonifying liver improving eyesight, kidney governing bones marrow, bone marrow hematogenesis, liver storing blood, therefore four have the constitutional function of good hemopoietic; The promoting the circulation of blood of enriching blood of Caulis Spatholobi, Radix Angelicae Sinensis, invigorates blood circulation, pain relieving, and intestine moistening function is improved tumor patient anemia, leukopenia, blood viscosity is high, cancer pain and being hard and dry, thus improve patient's diet, enhancing immunity, reduces the generation of complication, eliminates misery and stress that tumor is brought; The Squama Manis Xiao Disorder antitumor of invigorating blood circulation is strengthened antitumor action in the situation that ensureing healthy energy; Fructus Hordei Germinatus, the spleen invigorating of Poria stomach function regulating, appetite strengthening.
Poria: i.e. Poria, promoting diuresis to eliminate damp pathogen, invigorating middle warmer spleen invigorating, mind tranquilizing and the heart calming.
Rhizoma Polygonati: there is spleen reinforcing, the effect of the lung moistening and production of body fluid promoting.
Herba Epimedii: kidney invigorating and YANG supporting, expelling wind and removing dampness.Control sexual impotence erectile problem, apoplectic dyscinesia, dribbling urination, muscles and bones contraction is anxious, cough, optic atrohic blindness after being ill, toothache caused by fire of deficiency type, hemiplegia, weakness of the waist and knees, rheumatic arthralgia, extremity are meciless.
Fructus Psoraleae: kidney invigorating and YANG supporting, controlling nocturnal emission with astringent drugs reducing urination, lumbago due to renal deficiency, frequent micturition, bed-wetting, kidney leaks, warming spleen and stopping diarrha, helping inspiration to relieve asthma.
Caulis Spatholobi: the promoting the circulation of blood of enriching blood, the meridian dredging.
Preparation method of the present invention:
1. impurity in above-mentioned formula material is removed in roguing, will eluriate if desired, removes earth.
2. invade bubble and can adopt the containers such as ceramic cylinder, rustless steel, invade bubble with cold water, do not have crude drug to be advisable.Invading the bubble time should be no less than 30 minutes.
3. decoct first invading after the Radix Ginseng pannikin soaking decocts 20 minutes, again other is invaded to the raw material soaking together with the Radix Ginseng being decocted first, put into boiling machine and decoct, the decocting that adds for the first time 8 times boils 2 hours, the decocting that adds for the second time 6 times boils 1.5 hours, after decocting, the medicinal liquid of twice is filtered and is merged.
4. sterilizing medicinal liquid is through decocting, and most of harmful bacteria to be to kill, be to ensure product long storage time, and with after the fill of polyethylene Chinese medicine bag, Killing germs by microwave 1 minute immediately while hot.Obtain the product that " rises plain soup medicinal liquid " safely and effectively of the present invention.
Usage and dosage: oral, every day twice, sooner or later respectively once, within seven days, take potion, surrounding is a course for the treatment of.
This product possesses following advantage:
1. raw material source is abundant, and cheap, small investment of production equipment, is easily accepted by extensive patients.
2. through the clinical practice of hundreds of example, this Chinese medicine uses safety, convenience, Yi Hang, no pain, avirulence, splendid without anaphylaxis, curative effect.
3. the plain soup that rises of the present invention, can be alone in the time for the treatment of leukopenia, also can combine other shengbai drugs use simultaneously, all reaches good effect.And this product can also reduce the inhibition of chemicotherapy to bone marrow, also can improve immunity of organisms, strengthen the effects such as treatment curative effect.
4. the reimbursement ratio of Chinese herbal medicine in community-sponsored medical insurance is higher, has also just greatly alleviated the financial difficulties of tumor patient, also can make major contribution for Chinese Chinese medicine.
5. cure rate is up to 90% in clinical practice for medicinal liquid of the present invention, and most of patient can alonely rise plain soup and just can reach prevention and treat leukopenic effect.Finally reach and allow patient reduce the financial burden, improve body resistivity, reduce patient's misery, allow patient complete smoothly planned therapeutic scheme.
Detailed description of the invention
Embodiment 1
Leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy of the present invention, comprises the crude drug of following parts by weight: Herba Epimedii 105g, Fructus Psoraleae 70 g, Fructus Lycii 105g, Radix Ginseng 70g, Radix Astragali 140g, Radix Angelicae Sinensis 70g, Caulis Spatholobi 210g, Radix Glycyrrhizae 70g, Squama Manis 84g.
Preparation method of the present invention:
1. impurity in above-mentioned formula material is removed in roguing, will eluriate if desired, removes earth.
2. invade bubble and can adopt the containers such as ceramic cylinder, rustless steel, invade bubble with cold water, do not have crude drug to be advisable.Invading the bubble time should be no less than 30 minutes.
3. decoct first invading after the Radix Ginseng pannikin soaking decocts 20 minutes, again other is invaded to the raw material soaking together with the Radix Ginseng being decocted first, put into boiling machine and decoct, the decocting that adds for the first time 8 times boils 2 hours, the decocting that adds for the second time 6 times boils 1.5 hours, after decocting, the medicinal liquid of twice is filtered and is merged.
4. sterilizing medicinal liquid is through decocting, and most of harmful bacteria to be to kill, be to ensure product long storage time, and with after the fill of polyethylene Chinese medicine bag, Killing germs by microwave 1 minute immediately while hot.Obtain the product that " rises plain soup medicinal liquid " safely and effectively of the present invention.
Usage and dosage: oral, every day twice, sooner or later respectively once, within seven days, take potion, surrounding is a course for the treatment of.
Embodiment 2
Leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy of the present invention, comprises the crude drug of following parts by weight: Herba Epimedii 95g, Fructus Psoraleae 60 g, Fructus Lycii 95g, Radix Ginseng 60g, Radix Astragali 130g, Radix Angelicae Sinensis 60g, Caulis Spatholobi 200g, Radix Glycyrrhizae 60g, Squama Manis 74g.
All the other are identical with embodiment 1.
Embodiment 3
Leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy of the present invention, comprises the crude drug of following parts by weight: Herba Epimedii 115g, Fructus Psoraleae 80 g, Fructus Lycii 115g, Radix Ginseng 80g, Radix Astragali 150g, Radix Angelicae Sinensis 80g, Caulis Spatholobi 220g, Radix Glycyrrhizae 80g, Squama Manis 94g.
All the other are identical with embodiment 1.
Embodiment 4 clinical verifications
Summary of Clinical Research: the present invention is through carrying out clinical observation treatment to 200 routine patients, wherein male's 120 examples, women's 80 examples, age 18 was to 70 years old, be the leukopenia that chemotherapy causes, show as lusterless complexion or sallow, have a dizzy spell, weak, low grade fever night sweat, feel sick, inappetence, immunity of organisms be low inferior.
(1) Therapeutic Method:
The medicine of oral embodiment 1,2 or 3, every day twice, sooner or later respectively once, takes said medicine for seven days, and surrounding is a course for the treatment of.
(2) efficacy assessment standard:
Cure: the sings and symptomses such as weak, dizzy, inappetence disappear completely, it is normal that functional activity recovers, and it is normal that Index for examination recovers.
Effective: clinical symptoms is clearly better or part disappears, and Index for examination slightly take a favorable turn.
Invalid: clinical symptoms sign is without improvement.
(3) therapeutic effect:
Clinical cure 180 examples, account for 90%; Effective 20 examples, account for 10%; Invalid 0 example; Total effective rate 100%.
Embodiment 5
Leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy of the present invention, comprises the crude drug of following weight: Herba Epimedii 105g, Fructus Psoraleae 70 g, Fructus Lycii 105g, Radix Ginseng 70g, Radix Astragali 140g, Radix Angelicae Sinensis 70g, Caulis Spatholobi 210g, Radix Glycyrrhizae 70g, Squama Manis 84g, Rhizoma Polygonati 126g, Colla Corii Asini 84g, Radix Achyranthis Bidentatae 84g, Placenta Hominis 84g, Fructus Hordei Germinatus 105g, Poria 105g.
All the other are identical with embodiment 1.
Embodiment 6
Leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy of the present invention, comprises the crude drug of following parts by weight: Herba Epimedii 95g, Fructus Psoraleae 60 g, Fructus Lycii 95g, Radix Ginseng 60g, Radix Astragali 130g, Radix Angelicae Sinensis 60g, Caulis Spatholobi 200g, Radix Glycyrrhizae 60g, Squama Manis 74g, Rhizoma Polygonati 116g, Colla Corii Asini 74g, Radix Achyranthis Bidentatae 74g, Placenta Hominis 74g, Fructus Hordei Germinatus 95g, Poria 95g.
All the other are identical with embodiment 1.
Embodiment 7
Leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy of the present invention, comprises the crude drug of following parts by weight: Herba Epimedii 115g, Fructus Psoraleae 80 g, Fructus Lycii 115g, Radix Ginseng 80g, Radix Astragali 150g, Radix Angelicae Sinensis 80g, Caulis Spatholobi 220g, Radix Glycyrrhizae 80g, Squama Manis 94g, Rhizoma Polygonati 136g, Colla Corii Asini 94g, Radix Achyranthis Bidentatae 94g, Placenta Hominis 94g, Fructus Hordei Germinatus 115g, Poria 115g.
All the other are identical with embodiment 1.
Embodiment 8 clinical verifications
Summary of Clinical Research: the present invention is through carrying out clinical observation treatment to 200 routine patients, wherein male's 120 examples, women's 80 examples, age 18 was to 70 years old, be the leukopenia that chemotherapy causes, show as lusterless complexion or sallow, have a dizzy spell, weak, low grade fever night sweat, feel sick, inappetence, immunity of organisms be low inferior.
(4) Therapeutic Method:
Medicine described in oral embodiment 5,6 or 7, every day twice, sooner or later respectively once, and seven days complete said medicine, surrounding is a course for the treatment of.
(5) efficacy assessment standard:
Cure: the sings and symptomses such as weak, dizzy, inappetence disappear completely, it is normal that functional activity recovers, and it is normal that Index for examination recovers.
Effective: clinical symptoms is clearly better or part disappears, and Index for examination slightly take a favorable turn.
Invalid: clinical symptoms sign is without improvement.
(6) therapeutic effect:
Clinical cure 184 examples, account for 92%; Effective 16 examples, account for 8%; Invalid 0 example; Total effective rate 100%.
Model case:
Case one: Liu so-and-so, man, 63 years old, in JIUYUE, 2006 is suffered from pulmonary carcinoma, during with 2 cycle of GP scheme chemotherapy, occurs the bone marrow depression of II degree, gives after colony stimulating factor treatment after leukocyte rises to normally, giving the oral plain soup treatment that rises,, not there is not bone marrow depression in patient's 6 end cycles.
Case two: king so-and-so, man, 53 years old, suffer from pulmonary carcinoma in August, 2009, give to rise plain soup prevention leukopenia with NP scheme chemotherapy simultaneously, result patient is until there is not bone marrow depression in end of chemotherapy yet, and chemotherapeutic efficacy obviously increases.
Case three: Liu so-and-so; female, 43 years old, suffered from breast cancer in March, 2010; after row operative treatment; row surrounding phase TP scheme adjuvant chemotherapy again, therefore scheme bone marrow depression is heavier, rises plain soup therefore chemotherapeutic period is taken; patient is to end of chemotherapy; there is not bone marrow depression, protected body damage, alleviated financial burden yet.
Claims (4)
1. specially control leukopenic Chinese medicine of caused by radiotherapy and chemotherapy for one kind, it is characterized in that: the crude drug that comprises following parts by weight: Herba Epimedii 95-115 part, Fructus Psoraleae 60-80 part, Fructus Lycii 95-115 part, Radix Ginseng 60-80 part, Radix Astragali 130-150 part, Radix Angelicae Sinensis 60-80 part, Caulis Spatholobi 200-220 part, Radix Glycyrrhizae 60-80 part, Squama Manis 74-94 part.
2. leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy according to claim 1, is characterized in that: the crude drug that also comprises following parts by weight: Rhizoma Polygonati 116-136 part, Colla Corii Asini 74-94 part, Radix Achyranthis Bidentatae 74-94 part, Placenta Hominis 74-94 part, Fructus Hordei Germinatus 95-115 part, Poria 95-115 part.
3. leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy according to claim 1, it is characterized in that: the crude drug that comprises following parts by weight: 105 parts of Herba Epimedii, 70 parts of Fructus Psoraleaes, 105 parts of Fructus Lycii, 70 parts of Radix Ginsengs, 140 parts of the Radixs Astragali, 70 parts of Radix Angelicae Sinensis, 210 parts of Caulis Spatholobis, 70 parts, Radix Glycyrrhizae, 84 parts of Squama Maniss.
4. according to the leukopenic Chinese medicine of specially controlling caused by radiotherapy and chemotherapy described in claim 2 or 3, it is characterized in that: the crude drug that also comprises following parts by weight: 126 parts of Rhizoma Polygonatis, 84 parts, Colla Corii Asini, 84 parts of Radix Achyranthis Bidentataes, 84 parts of Placenta Hominiss, 105 parts, Fructus Hordei Germinatus, 105 parts of Poria.
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| CN104784608A (en) * | 2015-04-20 | 2015-07-22 | 王志海 | Preparation method of medicine for relieving toxic or side effects after tumor chemotherapy |
| CN113684109A (en) * | 2021-09-13 | 2021-11-23 | 天马（安徽）国药科技股份有限公司 | Formula and preparation method of ginseng, epimedium and dogwood health wine |
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| CN104784608A (en) * | 2015-04-20 | 2015-07-22 | 王志海 | Preparation method of medicine for relieving toxic or side effects after tumor chemotherapy |
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Address after: 274300 Zhengda hospital, Shun teachers Road, Heze, Shandong, Shanxian County Applicant after: Wang Zaifeng Address before: 250000, Ji'nan, Shandong West Industrial and Commercial Road Flyover District No. 2 Applicant before: Wang Zaifeng |
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